PANDEMIC - N 09 ISSUE - Know Science

 
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PANDEMIC - N 09 ISSUE - Know Science
21st PANDEMIC                   CENTURY

                                                                           PANDEMOS

 ISSUE
 N°09
Published
Published on August
             on     2020, Toronto, 2020,
                    September      CA www.knowscience.org/pandemos-news/
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PANDEMIC - N 09 ISSUE - Know Science
WHO ARE WE?
     As part of the University of Toronto’s
                                                                                                               @PANDEMOSNEWS
     COVID-19 engagement project, Pandemos
     is a team of undergrad students from across
     Canada and America in an initiative aimed
     at combating untrue information regarding
     the COVID-19 pandemic. We have two main                                                                   PANDEMOS
     goals - distribute true information on a reg-
     ular basis and answer public questions. Pri-
     marily, we provide people with the latest ac-
                                                                                                               HTTPS://KNOWSCIENCE.
     curate information on the pandemic, spread                                                                ORG/PANDEMOS-HOME/
     of the virus, control methods, impacts on
     life, advances in the academic field and var-
     ious news stories through our Social media,
     upcoming website, and our newsletter. Our
     second goal is to provide a platform from
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     The public sends in questions and we reply
     with answers verified by our team of subject
     matter experts via our social media/website/
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       Disclaimer: The views and information presented in this newsletter, the Pandemos website or Pandemos associated social media is
       not intended to be medical advice. We aim simply to disperse information as it becomes available in today’s ever-changing situation.

01
PANDEMIC - N 09 ISSUE - Know Science
CONTENTS
        03
     Meet The Team

        05
   Meet The Sponsors

        06
    Authored Article

        09
  Academic Research

        13
     News Update

        16
  Statistics and Trends

                          02
PANDEMIC - N 09 ISSUE - Know Science
MEET
        THE TEAM
     Chirag                                     hana

                     Chopra                                   sharifi
       PROJ EC T L E A D E R                     R E S E A RCH E R
       U N I V E RS I T Y O F TO RO N TO ‘ 22    U N I V E RS I T Y O F TO RO N TO ‘ 2 3
       LI FE SCI E N CE S                        LI FE SCI E N CE S

     Chinmayi                                   tanin

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      E D I TO R                                 R E S E A RCH E R
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      MEDICAL HUMANITIES                         LI FE SCI E N CE S

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      U N I V E RS I T Y O F TO RO N TO ‘ 24     U N I V E RS I T Y O F TO RO N TO ‘ 2 3
      SOCI A L SCI E N CE S                      I R , ECO N O M I C S & PU B LI C PO LI C Y

03
PANDEMIC - N 09 ISSUE - Know Science
PANDEMIC - N 09 ISSUE - Know Science
MEET THE
         SPONSORS
                      F U N D I N G

                                      U N I V E RS I T Y
                                      O F TO RO N TO

          MA R K E T I N G

     PROS PEC T I V E M E D I C A L                        K N OW
     PRO FE SS I O N A L S                                 SCI E N CE

05
PANDEMIC - N 09 ISSUE - Know Science
AUTHORED
 ARTICLE
 hana sharifi
                06
PANDEMIC - N 09 ISSUE - Know Science
DO MASKS IMPEDE CHILDREN’S
                      DEVELOPMENT?

     A
               nyone who has had to wear a       protocol have been getting questions
               mask for any purpose--wheth-      from concerned parents about whether
               er it be a student going back     masks – on children or their caregivers
     to school, a worker required to wear        – may interfere with various aspects of
     one in the workplace, or even a grocery     a child’s development, including speech,
     shopper running errands--knows that         language, and social interaction.
     it’s far from being easy. Thoughts be-
     come clouded, senses become impeded,        Dr. Kang Lee, a professor of applied
     breathing is more difficult, and you keep    psychology and human development at
     jabbing the straw into your mask when       the University of Toronto, who studies the
     you go to take a drink. All you want to     development of facial recognition skills in
     do is rip the mask of your face and take    children, validated the fears of parents by
     a deep breath of fresh air.                 acknowledging the problems that masks
                                                 may pose for children interacting with
     Though wearing masks can be very            classmates or teachers. In his research,
     uncomfortable, the evidence doesn’t lie     he has discovered that children under the
     – face coverings are a proven, effective    age of 12 may have difficulty recognizing
     way to prevent the spread of COVID-19.      people wearing masks since they often
     Beyond preventing the transmittance of      focus on individual features. Additionally,
     respiratory droplets from person to per-    they may struggle with emotional recog-
     son, another benefit of wearing masks        nition, since a lot of emotional informa-
     is that they may prevent people from        tion is displayed through the movement
     touching their mouths and faces with        of facial musculature, and they may also
     contaminated hands, another common          have problems with speech recognition
     way through which COVID-19 can be           because a lot of information (i.e. lip-read-
     spread.                                     ing) is communicated visually.

     Despite these facts, a new concern re-      David Lewkowicz, a senior scientist at
     garding masks has emerged from par-         the Haskins Laboratories and the Yale
     ents and families as their children begin   Child Study Center, has studied lip-read-
     to return to school and childcare. Pedi-    ing in babies in his research. He has
     atrician colleagues who are helping to      discovered that around the ages of 6 to
     develop guidelines on proper masking        8 months, babies begin concentrating on

07
PANDEMIC - N 09 ISSUE - Know Science
speakers’ mouths, rather than eyes, to          SOURCES:
gather visual cues in addition to auditory.
                                                https://www.nytimes.com/2020/09/14/
“Masks are not a great thing for commu-         well/family/Masks-child-development.
nication in young kinds,” Dr. Lewkowicz         html

acknowledges. However, he is hopeful
                                                https://www.healthychildren.org/English/
that children will still be able to thrive by
                                                health-issues/conditions/COVID-19/Pag-
utilizing more creative methods of com-
                                                es/Mask-Mythbusters.aspx
munication, such as through hand ges-
tures and body language. In fact, finding        https://www.aappublications.org/
new ways to communicate may offer a             news/2020/08/13/covid19facecover-
unique opportunity for children to learn        ings081320
and adapt. Techniques that children with
autism already use may prove to be par-         https://www.sciencedirect.com/science/
                                                article/abs/pii/S0022096501926396
ticularly useful, including paying atten-
tion to the tone of voice, gestures, overall
body language, reading people’s eyes
and eyebrows, and recognizing repeti-
tive hairstyles and clothing choices of the
people they interact with.

Eva Chen, a developmental psycholo-
gist who is an associate professor at the
Hong Kong University of Science and
Technology, also points out that there
is no evidence suggesting that children
of countries in Asia, who routinely wear
masks in times of illness or air pollution,
grow up any worse at recognizing faces
or emotions.

“Kids are very, very adaptive, more adap-
tive than we are – they should learn very
quickly,” Dr. Lee said. “I don’t think par-
ents should be too worried.”

                                                                                           08
PANDEMIC - N 09 ISSUE - Know Science
ACADEMIC
     RESEARCH
     CHINMAYI BALUSU

09
the disease” in order to “identify possible
FROM SARS TO                                    preventive and therapeutic strategies”
COVID-19: WHAT WE                               for young patient populations.
HAVE LEARNED ABOUT
CHILDREN INFECTED                               COVID-19, Virology
                                                and Geroscience: A
WITH COVID-19
       Authors: Meng-Yao Zhou, Xiao-            Perspective - Aging
          Li Xie, Yong-Gang Peng, et al         and COVID-19
            https://www.ncbi.nlm.nih.gov/pmc/
                                                              Authors: Camille Vellas, P.
                       articles/PMC7204709/          Delobel, P. De Souto Barreto, et al
      Younger     children    have     been                 https://www.ncbi.nlm.nih.gov/pmc/
found to be equally susceptible to                                     articles/PMC7301052/

COVID-19 as many older adults. Recent                 Older adults have been reported
COVID-19 literature focusing on the             to   be   much        more   susceptible   to
impact of COVID-19 on children has              COVID-19 since the beginning of the
detailed how newborns with COVID-19             pandemic. In this article, the authors
positive mothers as well as children who        address the importance of geroscience
experience gastrointestinal symptoms            (“an interdisciplinary field that seeks
at the start of the illness may be likely to    to understand the links of biological
have severe complications. It’s difficult        mechanisms of aging with biological
to   draw   concrete    conclusions     and     mechanisms       of    disease     and   body
recommendations, however, since there           functions [...] to ultimately find potential
is currently limited pediatric patient data     interventions and promote health in older
related to COVID-19. The authors draw           adults”) as an approach understanding,
on SARS findings that illustrate details         addressing, and preventing COVID-19’s
about the transmission of the virus in          damaging effects to elderly citizens. It
children as well as risk factors linked         is important to address that COVID-19
with neutrophils and various cells in           does not affect all older adults in the
children’s bodies. However, not all of the      same way, and the aging population
predicted parallels between SARS and            is   “heterogeneous.”        The    outcomes
COVID-19 prove relevant. For example,           of COVID-19 are also dependent on
SARS-CoV-2 has higher transmission,             comorbidities such as obesity, diabetes,
possibly because pulmonary guidelines           cardiovascular, and hypertension, which
are differing and asymptomatic children         can differ from elder to elder. The condition
are more commonly overlooked. This              of “frailty” also needs to be taken into
article illustrates the need for “[defining]     account, and this may originate from
the clinical characteristics and severity of    immunosenescence and inflammaging

                                                                                                10
during aging processes. This can then             exact potential link between neurological
     potentially cause chronic inflammation             and respiratory effects are, especially
     as well as other predisposing conditions          considering that the researchers have
     that can affect how SARS-CoV-2 can                only conducted studies analyzing SARS-
     lead to serious COVID-19 complications.           CoV and not SARS-CoV-2 to date in this
                                                       vein--while the predicted parallels may
     THE NEUROINVASIVE                                 definitely carry weight, it is not clearly
     POTENTIAL OF SARS-                                defined if this is actually how SARS-
     COV2 MAY PLAY A ROLE                              CoV-2 interacts with the nervous system.
     IN THE RESPIRATORY
     FAILURE OF COVID-19
     PATIENTS
            Authors: Yan-Chao Li, Wan-Zhu
              Bai, and Tsutomu Hashikawa
              https://www.ncbi.nlm.nih.gov/pmc/arti-
                                 cles/PMC7228394/

            Scientists from Norman Bethune
     College of Medicine, China Academy
     of Chinese Medical Science, and the                THINGS MUST NOT
     RIKEN Brain Science Institute report              FALL APART: THE
     that understanding the “neuroinvasion”
                                                       RIPPLE EFFECTS
     SARS-CoV-2 initiates may potentially
     have     “guiding       significance”        in
                                                       OF THE COVID-19
     understanding the respiratory failure             PANDEMIC ON
     that the virus causes. The scientists took        CHILDREN IN SUB-
     into account similarities between SARS-
                                                       SAHARAN AFRICA
     CoV and SARS-CoV-2 and found it likely
                                                                      Authors: Modupe Coker,
     that the current virus may potentially
                                                       Morenike Folayan, Ian Michelow, et al
     enter the central nervous system (which                 https://www.nature.com/articles/s41390-
                                                                                       020-01174-y
     includes the brain and spinal cord)
                                                             Historically,   children    in   sub-
     through peripheral nerve terminals and
                                                       Saharan Africa have been greatly at
     then affect a synapse-connected route);
                                                       risk for facing the “disproportionate
     other earlier studies also suggested the
                                                       burden of communicable and non-
     possible entry point through olfactory
                                                       communicable diseases globally.” The
     nerves    and     passing     through      the
                                                       COVID-19 pandemic doesn’t change
     thalamus and brainstem in the brain.
                                                       that: there is very little study on how
     However, it remains unclear what the

11
the current pandemic has affected sub-
Saharan African children under the
age of 19 years old. In this narrative
review, researchers address the gaps
in   pediatric   disease    research    and
lack of SARS-CoV-2 co-infections/co-
morbidities in children in sub-Saharan
Africa. The authors providing extensive
statistics on undernutrition, malaria,
vaccine-preventable        diseases    (such
as   diarrhea    and   pneumonia),      HIV,
tuberculosis, and sickle cell disease;
additionally, the impact of domestic,
family, and sexual violence and loss
of social preventions on children is
detailed (for instance, “Kenya reported
a 34% rise in domestic violence, while
in South Africa, there was a 37% spike
in gender-based violence complaints in
the first week of a total lockdown”). In
conclusion, they address that while the
COVID-19 has greatly exacerbated poor
conditions for children in sub-Saharan
Africa, this is also the time for change to
be accelerated through “targeted [and]
comprehensive/cross-cutting action.”

                                               12
NEWS UPDATE

     JOSHUA CHONG
13
CANADIAN GOVERN-                              more Canadians who are suffering” and
                                              has no plan to address the mounting
MENT CHARTS PATH                              deficit. The Bloc Quebecois said they will
FORWARD IN THRONE                             not support the speech unless the gov-

SPEECH                                        ernment agrees to at least $28 billion
                                              in health transfer to provinces. Jagmeet
      A month after hitting the reset
                                              Singh, the leader of the NDP, did not in-
button by proroguing parliament, Prime
                                              dicate if his party will support or reject
Minister Justin Trudeau’s government
                                              the speech, but highlight that he wants
outlined their priorities for the next ses-
                                              to see greater support for worker in the
sion of parliament in a throne speech
                                              form of paid sick leave and an extension
delivered by Governor General Julie Pay-
                                              of the Canada Emergency Response
ette on September 23. The plan focused
                                              Benefit.
heavily on the COVID-19 pandemic and
outlines the establishment of a Test-
ing Assistance Response Team that             TORONTO DISTRICT
will identify surges for testing demand
across the country. The speech also dou-
                                              SCHOOL BOARD FACING
bled down on the government’s pledge          STAFFING CHALLENGES
to implement universal pharmacare. In
                                              AS CLASSES RESUME
response to the impact of the pandem-
                                                    The Toronto District School Board
ic in long-term care homes, Trudeau’s
                                              (TDSB), the largest school district in
Liberals promised to create nationwide
                                              Canada, is facing multiple hurdles as it
standards for long-term care. In addi-
                                              tries to adapt to the pandemic learning
tion, the Canada Emergency Wage Sub-
                                              environment. Nearly two weeks after
sidy will be extended until next summer.
                                              classes resumed, the board hired an
Despite calls from premiers, the gov-
                                              additional 350 teachers as it tries to
ernment did not indicate in the throne
                                              mitigate staff shortages. According to
speech that it will increase health trans-
                                              TDSB spokesperson Ryan Bird, demand
fers to the provinces. Following debate,
                                              for the school board’s online learning
the throne speech will be voted on in
                                              option increased from 56 000 to 78 000
parliament. The minority Liberals need
                                              in a matter of weeks. He indicated that
the support of either the Conservative,
                                              in all, the TDSB needs approximately
Bloc Quebecois, or NDP in order to avoid
                                              500 additional teachers. When students
the toppling of government and a fall
                                              opting for online learning logged in for the
election. The Conservatives rejected the
                                              first time in mid-September, thousands
speech and indicated that they will vote
                                              were not assigned a teacher and are
against it, saying that it “leaves behind
                                              expected to learn independently until one

                                                                                             14
is assigned. In late September, the school     been met with mixed responses from
     board allowed students and parents to          politicians and those in the healthcare
     opt for either in person or online learning.   sector. Dr. Anthony Fauci, America’s top
     Currently, 60 000 elementary students          infectious disease specialist, said, “The
     and 18 000 secondary students signed           idea of 200,000 deaths is really very
     up for the online program. The TDSB            sobering, in some respects stunning.”
     was also been notified of issues with           President Donald Trump, however, said
     Brightspace, the online platform used          at a rally on September 21 that the
     for virtual programming, after several         pandemic “affects virtually nobody”.
     students were unable to log in. The board
     said it has deployed additional technical
     resources to mitigate the problem.             SOURCES:
                                                    https://www.theglobeandmail.com/pol-
                                                    itics/article-pandemic-throne-speech-tru-
                                                    deau-explainer/
     U.S. COVID-19 DEATH
                                                    https://www.cp24.com/tdsb-hires-350-
     TOLL OFFICALLY                                 teachers-as-it-scrambles-to-fill-class-
     SURPASSES 200 000,                             rooms-for-virtual-school-1.5115065

     JUST EIGHT MONTHS
                                                    https://www.cbc.ca/news/world/
     AFTER THE START OF                             us-200k-coronavirus-sum-
     THE PANDEMIC                                   mary-1.5733956
           Merely eight months since the
     start of the pandemic, the U.S. officially
     surpassed 200 000 deaths due to
     COVID-19 on September 22. The grim
     milestone, announced by Johns Hopkins,
     is the highest in the world, though the
     real death toll in the country is predicted
     to be much higher. On average, 770
     individuals die from the virus each day in
     the U.S. According to projections by the
     University of Washington, the death toll
     could double to 400 000 before the end of
     the year, due to reopening policies across
     the country. The staggering number has

15
STATISTICS
& TRENDS

TANIN KHORRAMI
      TAJ
                 16
ARE CANADIANS FACING A SECOND
                       WAVE?

     A
              s we approach mid-September,         In the United States, state-level reports
              it has been reported by Public       are the best publicly available data on
              Health officials that there has       child COVID-19 cases. The American
     been a rapid increase in new COVID-19         Academy of Pediatrics and the Chil-
     cases in provinces across Canada. In          dren’s Hospital Association have collab-
     recent weeks alone, Ontario reported          orated to collect and share data from
     its highest single-day increase in new        states on child COVID-19 cases, and
     confirmed cases of COVID-19 since early        on August 27, the health department
     June, with 401 confirmed cases as more         websites of 49 states provided data on
     than 35,800 tests were completed. The         reported COVID-19 cases, distributed
     Ontario Health Minister, Christine Elliott,   by age. Although children represent just
     declared that 67% of recent cases have        9.5% of all cases in these states, over
     been found in people under the age of         476,000 children have tested positive
     40. Moreover, with an increased number        for the virus since the beginning of the
     of cases in those who are 20 to 39 years      pandemic. However, COVID-19-asso-
     of age, even though this group makes up       ciated hospitalization and death are
     only 14% of the province’s population.        uncommon in children. It appears that
                                                   severe illness due to COVID-19 is rare
     With that in mind, as daily case counts       among children.
     increase at an alarming rate, does this
     mean that a second wave of the pan-           Additionally, provinces have now start-
     demic will soon be declared?                  ed to take regional base measures in an
     Canada’s top Public Health official, Dr.       attempt to slow down the spread of the
     Theresa Tam, said that it is indeed too       virus.
     early to declare a second wave, howev-
     er, with cases on a rise, it increases the    Toronto, Ottawa, and Peel region cut
     likelihood of losing the ability to keep      down the limit of 25 people for indoor
     COVID-19 cases at manageable levels.          gatherings to 10 and dropped outdoor
     She also mentions that as Canadians,          gatherings from 100 to 25.
     now is the time to redouble our effort
     with personal precautions that will slow      Quebec has also announced that police
     down the spread of COVID-19.                  officers will be visiting over 1,000 bars,
                                                   restaurants and other establishments

17
with alcohol permits to ensure that           elbow or sleeve, not your hands.
rules are being respected.
                                             • Wear cloth face-covering in a public
The figures below demonstrate the rise         setting to cover your mouth and
in confirmed cases in Canada, as of            nose, to protect yourself and those
September 18th, 2020.                         around you.

Furthermore regarding current                • Wear reusable or disposable gloves
trends, here are some precautions to          for routine cleaning and disinfection.
keep in mind:
                                             • Clean surfaces using soap and
 • Wash your hands regularly with             water, to reduce the number of
   soap and water for at least 20             germs, dirt and impurities on the
   seconds. However, If soap and water        surface. Then use disinfectant, to kill
   are not in sight, use a hand sanitizer     off any germs on the surface.
   with at least 60% alcohol.
                                             • In case someone in the household is
 • When coughing or sneezing, cover           sick, if it is possible, keep a separate
   your nose and mouth with a tissue to       bedroom and bathroom for the
   throw away after use. If a tissue isn’t    person who is sick.
   available, cough or sneeze into your

                                                                                         18
Figure 1: The following map indicates the total cases of COVID-19 in Canada, as
     of September 18th, 2020.
     Source: https://www.canada.ca/en/public-health/services/diseases/2019-novel-corona-
     virus-infection.html#a1

19
Figure 2: As of September 18th, 2020, this data indicates the cumulative total of
COVID-19 cases across Canada, and how the graph seems to be on a rise.
Source: https://www.macleans.ca/society/health/coronavirus-in-canada-these-charts-
show-how-our-fight-to-flatten-the-curve-is-going/

                                                                                     20
SOURCES:
     https://globalnews.ca/news/7343465/
     ontario-coronavirus-cases-septem-
     ber-18-covid19/

     https://globalnews.ca/news/7344377/
     coronavirus-canada-second-wave-2/
     https://www.cbc.ca/news/canada/
     toronto/covid-19-ontario-cases-da-
     ta-1.5726687

     https://globalnews.ca/news/7343422/
     quebec-coronavirus-measures-guil-
     bault/

     https://www.cdc.gov/coronavi-
     rus/2019-ncov/prevent-getting-sick/dis-
     infecting-your-home.html

21
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