PANDEMIC - N 09 ISSUE - Know Science
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21st PANDEMIC CENTURY PANDEMOS ISSUE N°09 Published Published on August on 2020, Toronto, 2020, September CA www.knowscience.org/pandemos-news/ Toronto, CA www.knowscience.org/pandemos-news/
WHO ARE WE? As part of the University of Toronto’s @PANDEMOSNEWS COVID-19 engagement project, Pandemos is a team of undergrad students from across Canada and America in an initiative aimed at combating untrue information regarding the COVID-19 pandemic. We have two main PANDEMOS goals - distribute true information on a reg- ular basis and answer public questions. Pri- marily, we provide people with the latest ac- HTTPS://KNOWSCIENCE. curate information on the pandemic, spread ORG/PANDEMOS-HOME/ of the virus, control methods, impacts on life, advances in the academic field and var- ious news stories through our Social media, upcoming website, and our newsletter. Our second goal is to provide a platform from which we can connect the public to experts. This is in the form of a Public Q&A portion of our social media, website and newsletter. The public sends in questions and we reply with answers verified by our team of subject matter experts via our social media/website/ newsletter outlets. Disclaimer: The views and information presented in this newsletter, the Pandemos website or Pandemos associated social media is not intended to be medical advice. We aim simply to disperse information as it becomes available in today’s ever-changing situation. 01
CONTENTS 03 Meet The Team 05 Meet The Sponsors 06 Authored Article 09 Academic Research 13 News Update 16 Statistics and Trends 02
MEET THE TEAM Chirag hana Chopra sharifi PROJ EC T L E A D E R R E S E A RCH E R U N I V E RS I T Y O F TO RO N TO ‘ 22 U N I V E RS I T Y O F TO RO N TO ‘ 2 3 LI FE SCI E N CE S LI FE SCI E N CE S Chinmayi tanin Balusu khorrami taj E D I TO R R E S E A RCH E R CO LU M B I A U N I V E RS I T Y ‘ 2 3 M CM A S T E R U N I V E RS I T Y ‘ 2 3 MEDICAL HUMANITIES LI FE SCI E N CE S joshua Paranjay chong Sahanii R E S E A RCH E R MARKETING U N I V E RS I T Y O F TO RO N TO ‘ 24 U N I V E RS I T Y O F TO RO N TO ‘ 2 3 SOCI A L SCI E N CE S I R , ECO N O M I C S & PU B LI C PO LI C Y 03
MEET THE SPONSORS F U N D I N G U N I V E RS I T Y O F TO RO N TO MA R K E T I N G PROS PEC T I V E M E D I C A L K N OW PRO FE SS I O N A L S SCI E N CE 05
DO MASKS IMPEDE CHILDREN’S DEVELOPMENT? A nyone who has had to wear a protocol have been getting questions mask for any purpose--wheth- from concerned parents about whether er it be a student going back masks – on children or their caregivers to school, a worker required to wear – may interfere with various aspects of one in the workplace, or even a grocery a child’s development, including speech, shopper running errands--knows that language, and social interaction. it’s far from being easy. Thoughts be- come clouded, senses become impeded, Dr. Kang Lee, a professor of applied breathing is more difficult, and you keep psychology and human development at jabbing the straw into your mask when the University of Toronto, who studies the you go to take a drink. All you want to development of facial recognition skills in do is rip the mask of your face and take children, validated the fears of parents by a deep breath of fresh air. acknowledging the problems that masks may pose for children interacting with Though wearing masks can be very classmates or teachers. In his research, uncomfortable, the evidence doesn’t lie he has discovered that children under the – face coverings are a proven, effective age of 12 may have difficulty recognizing way to prevent the spread of COVID-19. people wearing masks since they often Beyond preventing the transmittance of focus on individual features. Additionally, respiratory droplets from person to per- they may struggle with emotional recog- son, another benefit of wearing masks nition, since a lot of emotional informa- is that they may prevent people from tion is displayed through the movement touching their mouths and faces with of facial musculature, and they may also contaminated hands, another common have problems with speech recognition way through which COVID-19 can be because a lot of information (i.e. lip-read- spread. ing) is communicated visually. Despite these facts, a new concern re- David Lewkowicz, a senior scientist at garding masks has emerged from par- the Haskins Laboratories and the Yale ents and families as their children begin Child Study Center, has studied lip-read- to return to school and childcare. Pedi- ing in babies in his research. He has atrician colleagues who are helping to discovered that around the ages of 6 to develop guidelines on proper masking 8 months, babies begin concentrating on 07
speakers’ mouths, rather than eyes, to SOURCES: gather visual cues in addition to auditory. https://www.nytimes.com/2020/09/14/ “Masks are not a great thing for commu- well/family/Masks-child-development. nication in young kinds,” Dr. Lewkowicz html acknowledges. However, he is hopeful https://www.healthychildren.org/English/ that children will still be able to thrive by health-issues/conditions/COVID-19/Pag- utilizing more creative methods of com- es/Mask-Mythbusters.aspx munication, such as through hand ges- tures and body language. In fact, finding https://www.aappublications.org/ new ways to communicate may offer a news/2020/08/13/covid19facecover- unique opportunity for children to learn ings081320 and adapt. Techniques that children with autism already use may prove to be par- https://www.sciencedirect.com/science/ article/abs/pii/S0022096501926396 ticularly useful, including paying atten- tion to the tone of voice, gestures, overall body language, reading people’s eyes and eyebrows, and recognizing repeti- tive hairstyles and clothing choices of the people they interact with. Eva Chen, a developmental psycholo- gist who is an associate professor at the Hong Kong University of Science and Technology, also points out that there is no evidence suggesting that children of countries in Asia, who routinely wear masks in times of illness or air pollution, grow up any worse at recognizing faces or emotions. “Kids are very, very adaptive, more adap- tive than we are – they should learn very quickly,” Dr. Lee said. “I don’t think par- ents should be too worried.” 08
the disease” in order to “identify possible FROM SARS TO preventive and therapeutic strategies” COVID-19: WHAT WE for young patient populations. HAVE LEARNED ABOUT CHILDREN INFECTED COVID-19, Virology and Geroscience: A WITH COVID-19 Authors: Meng-Yao Zhou, Xiao- Perspective - Aging Li Xie, Yong-Gang Peng, et al and COVID-19 https://www.ncbi.nlm.nih.gov/pmc/ Authors: Camille Vellas, P. articles/PMC7204709/ Delobel, P. De Souto Barreto, et al Younger children have been https://www.ncbi.nlm.nih.gov/pmc/ found to be equally susceptible to articles/PMC7301052/ COVID-19 as many older adults. Recent Older adults have been reported COVID-19 literature focusing on the to be much more susceptible to impact of COVID-19 on children has COVID-19 since the beginning of the detailed how newborns with COVID-19 pandemic. In this article, the authors positive mothers as well as children who address the importance of geroscience experience gastrointestinal symptoms (“an interdisciplinary field that seeks at the start of the illness may be likely to to understand the links of biological have severe complications. It’s difficult mechanisms of aging with biological to draw concrete conclusions and mechanisms of disease and body recommendations, however, since there functions [...] to ultimately find potential is currently limited pediatric patient data interventions and promote health in older related to COVID-19. The authors draw adults”) as an approach understanding, on SARS findings that illustrate details addressing, and preventing COVID-19’s about the transmission of the virus in damaging effects to elderly citizens. It children as well as risk factors linked is important to address that COVID-19 with neutrophils and various cells in does not affect all older adults in the children’s bodies. However, not all of the same way, and the aging population predicted parallels between SARS and is “heterogeneous.” The outcomes COVID-19 prove relevant. For example, of COVID-19 are also dependent on SARS-CoV-2 has higher transmission, comorbidities such as obesity, diabetes, possibly because pulmonary guidelines cardiovascular, and hypertension, which are differing and asymptomatic children can differ from elder to elder. The condition are more commonly overlooked. This of “frailty” also needs to be taken into article illustrates the need for “[defining] account, and this may originate from the clinical characteristics and severity of immunosenescence and inflammaging 10
during aging processes. This can then exact potential link between neurological potentially cause chronic inflammation and respiratory effects are, especially as well as other predisposing conditions considering that the researchers have that can affect how SARS-CoV-2 can only conducted studies analyzing SARS- lead to serious COVID-19 complications. CoV and not SARS-CoV-2 to date in this vein--while the predicted parallels may THE NEUROINVASIVE definitely carry weight, it is not clearly POTENTIAL OF SARS- defined if this is actually how SARS- COV2 MAY PLAY A ROLE CoV-2 interacts with the nervous system. IN THE RESPIRATORY FAILURE OF COVID-19 PATIENTS Authors: Yan-Chao Li, Wan-Zhu Bai, and Tsutomu Hashikawa https://www.ncbi.nlm.nih.gov/pmc/arti- cles/PMC7228394/ Scientists from Norman Bethune College of Medicine, China Academy of Chinese Medical Science, and the THINGS MUST NOT RIKEN Brain Science Institute report FALL APART: THE that understanding the “neuroinvasion” RIPPLE EFFECTS SARS-CoV-2 initiates may potentially have “guiding significance” in OF THE COVID-19 understanding the respiratory failure PANDEMIC ON that the virus causes. The scientists took CHILDREN IN SUB- into account similarities between SARS- SAHARAN AFRICA CoV and SARS-CoV-2 and found it likely Authors: Modupe Coker, that the current virus may potentially Morenike Folayan, Ian Michelow, et al enter the central nervous system (which https://www.nature.com/articles/s41390- 020-01174-y includes the brain and spinal cord) Historically, children in sub- through peripheral nerve terminals and Saharan Africa have been greatly at then affect a synapse-connected route); risk for facing the “disproportionate other earlier studies also suggested the burden of communicable and non- possible entry point through olfactory communicable diseases globally.” The nerves and passing through the COVID-19 pandemic doesn’t change thalamus and brainstem in the brain. that: there is very little study on how However, it remains unclear what the 11
the current pandemic has affected sub- Saharan African children under the age of 19 years old. In this narrative review, researchers address the gaps in pediatric disease research and lack of SARS-CoV-2 co-infections/co- morbidities in children in sub-Saharan Africa. The authors providing extensive statistics on undernutrition, malaria, vaccine-preventable diseases (such as diarrhea and pneumonia), HIV, tuberculosis, and sickle cell disease; additionally, the impact of domestic, family, and sexual violence and loss of social preventions on children is detailed (for instance, “Kenya reported a 34% rise in domestic violence, while in South Africa, there was a 37% spike in gender-based violence complaints in the first week of a total lockdown”). In conclusion, they address that while the COVID-19 has greatly exacerbated poor conditions for children in sub-Saharan Africa, this is also the time for change to be accelerated through “targeted [and] comprehensive/cross-cutting action.” 12
NEWS UPDATE JOSHUA CHONG 13
CANADIAN GOVERN- more Canadians who are suffering” and has no plan to address the mounting MENT CHARTS PATH deficit. The Bloc Quebecois said they will FORWARD IN THRONE not support the speech unless the gov- SPEECH ernment agrees to at least $28 billion in health transfer to provinces. Jagmeet A month after hitting the reset Singh, the leader of the NDP, did not in- button by proroguing parliament, Prime dicate if his party will support or reject Minister Justin Trudeau’s government the speech, but highlight that he wants outlined their priorities for the next ses- to see greater support for worker in the sion of parliament in a throne speech form of paid sick leave and an extension delivered by Governor General Julie Pay- of the Canada Emergency Response ette on September 23. The plan focused Benefit. heavily on the COVID-19 pandemic and outlines the establishment of a Test- ing Assistance Response Team that TORONTO DISTRICT will identify surges for testing demand across the country. The speech also dou- SCHOOL BOARD FACING bled down on the government’s pledge STAFFING CHALLENGES to implement universal pharmacare. In AS CLASSES RESUME response to the impact of the pandem- The Toronto District School Board ic in long-term care homes, Trudeau’s (TDSB), the largest school district in Liberals promised to create nationwide Canada, is facing multiple hurdles as it standards for long-term care. In addi- tries to adapt to the pandemic learning tion, the Canada Emergency Wage Sub- environment. Nearly two weeks after sidy will be extended until next summer. classes resumed, the board hired an Despite calls from premiers, the gov- additional 350 teachers as it tries to ernment did not indicate in the throne mitigate staff shortages. According to speech that it will increase health trans- TDSB spokesperson Ryan Bird, demand fers to the provinces. Following debate, for the school board’s online learning the throne speech will be voted on in option increased from 56 000 to 78 000 parliament. The minority Liberals need in a matter of weeks. He indicated that the support of either the Conservative, in all, the TDSB needs approximately Bloc Quebecois, or NDP in order to avoid 500 additional teachers. When students the toppling of government and a fall opting for online learning logged in for the election. The Conservatives rejected the first time in mid-September, thousands speech and indicated that they will vote were not assigned a teacher and are against it, saying that it “leaves behind expected to learn independently until one 14
is assigned. In late September, the school been met with mixed responses from board allowed students and parents to politicians and those in the healthcare opt for either in person or online learning. sector. Dr. Anthony Fauci, America’s top Currently, 60 000 elementary students infectious disease specialist, said, “The and 18 000 secondary students signed idea of 200,000 deaths is really very up for the online program. The TDSB sobering, in some respects stunning.” was also been notified of issues with President Donald Trump, however, said Brightspace, the online platform used at a rally on September 21 that the for virtual programming, after several pandemic “affects virtually nobody”. students were unable to log in. The board said it has deployed additional technical resources to mitigate the problem. SOURCES: https://www.theglobeandmail.com/pol- itics/article-pandemic-throne-speech-tru- deau-explainer/ U.S. COVID-19 DEATH https://www.cp24.com/tdsb-hires-350- TOLL OFFICALLY teachers-as-it-scrambles-to-fill-class- SURPASSES 200 000, rooms-for-virtual-school-1.5115065 JUST EIGHT MONTHS https://www.cbc.ca/news/world/ AFTER THE START OF us-200k-coronavirus-sum- THE PANDEMIC mary-1.5733956 Merely eight months since the start of the pandemic, the U.S. officially surpassed 200 000 deaths due to COVID-19 on September 22. The grim milestone, announced by Johns Hopkins, is the highest in the world, though the real death toll in the country is predicted to be much higher. On average, 770 individuals die from the virus each day in the U.S. According to projections by the University of Washington, the death toll could double to 400 000 before the end of the year, due to reopening policies across the country. The staggering number has 15
STATISTICS & TRENDS TANIN KHORRAMI TAJ 16
ARE CANADIANS FACING A SECOND WAVE? A s we approach mid-September, In the United States, state-level reports it has been reported by Public are the best publicly available data on Health officials that there has child COVID-19 cases. The American been a rapid increase in new COVID-19 Academy of Pediatrics and the Chil- cases in provinces across Canada. In dren’s Hospital Association have collab- recent weeks alone, Ontario reported orated to collect and share data from its highest single-day increase in new states on child COVID-19 cases, and confirmed cases of COVID-19 since early on August 27, the health department June, with 401 confirmed cases as more websites of 49 states provided data on than 35,800 tests were completed. The reported COVID-19 cases, distributed Ontario Health Minister, Christine Elliott, by age. Although children represent just declared that 67% of recent cases have 9.5% of all cases in these states, over been found in people under the age of 476,000 children have tested positive 40. Moreover, with an increased number for the virus since the beginning of the of cases in those who are 20 to 39 years pandemic. However, COVID-19-asso- of age, even though this group makes up ciated hospitalization and death are only 14% of the province’s population. uncommon in children. It appears that severe illness due to COVID-19 is rare With that in mind, as daily case counts among children. increase at an alarming rate, does this mean that a second wave of the pan- Additionally, provinces have now start- demic will soon be declared? ed to take regional base measures in an Canada’s top Public Health official, Dr. attempt to slow down the spread of the Theresa Tam, said that it is indeed too virus. early to declare a second wave, howev- er, with cases on a rise, it increases the Toronto, Ottawa, and Peel region cut likelihood of losing the ability to keep down the limit of 25 people for indoor COVID-19 cases at manageable levels. gatherings to 10 and dropped outdoor She also mentions that as Canadians, gatherings from 100 to 25. now is the time to redouble our effort with personal precautions that will slow Quebec has also announced that police down the spread of COVID-19. officers will be visiting over 1,000 bars, restaurants and other establishments 17
with alcohol permits to ensure that elbow or sleeve, not your hands. rules are being respected. • Wear cloth face-covering in a public The figures below demonstrate the rise setting to cover your mouth and in confirmed cases in Canada, as of nose, to protect yourself and those September 18th, 2020. around you. Furthermore regarding current • Wear reusable or disposable gloves trends, here are some precautions to for routine cleaning and disinfection. keep in mind: • Clean surfaces using soap and • Wash your hands regularly with water, to reduce the number of soap and water for at least 20 germs, dirt and impurities on the seconds. However, If soap and water surface. Then use disinfectant, to kill are not in sight, use a hand sanitizer off any germs on the surface. with at least 60% alcohol. • In case someone in the household is • When coughing or sneezing, cover sick, if it is possible, keep a separate your nose and mouth with a tissue to bedroom and bathroom for the throw away after use. If a tissue isn’t person who is sick. available, cough or sneeze into your 18
Figure 1: The following map indicates the total cases of COVID-19 in Canada, as of September 18th, 2020. Source: https://www.canada.ca/en/public-health/services/diseases/2019-novel-corona- virus-infection.html#a1 19
Figure 2: As of September 18th, 2020, this data indicates the cumulative total of COVID-19 cases across Canada, and how the graph seems to be on a rise. Source: https://www.macleans.ca/society/health/coronavirus-in-canada-these-charts- show-how-our-fight-to-flatten-the-curve-is-going/ 20
SOURCES: https://globalnews.ca/news/7343465/ ontario-coronavirus-cases-septem- ber-18-covid19/ https://globalnews.ca/news/7344377/ coronavirus-canada-second-wave-2/ https://www.cbc.ca/news/canada/ toronto/covid-19-ontario-cases-da- ta-1.5726687 https://globalnews.ca/news/7343422/ quebec-coronavirus-measures-guil- bault/ https://www.cdc.gov/coronavi- rus/2019-ncov/prevent-getting-sick/dis- infecting-your-home.html 21
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