Our Guide: How a Trusted Hemp Cannabinoid Partner Can Strengthen Your Business
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Our Guide: How a Trusted Hemp Cannabinoid Partner Can Strengthen Your Business
Introduction
Deciding which hemp cannabinoid manufacturer to partner with is one of the most significant decisions that
a business owner of a hemp consumer brand will ever make. From the top down, each decision that hemp
cannabinoid manufacturers and suppliers make will ultimately reflect on your business. After all, you’re selling
these products with CBD, CBG or CBN to your customers, and they’re trusting you with their wellness. It’s
essential to make sure that every step of the process — from farming to manufacturing — is current with licenses,
certifications, and that third-party lab testing is completed. But even more importantly, the manufacturer you
choose must deliver on the science of its product, the scale in their offering, and innovation. Are they looking
beyond the current market trends? These are the cornerstones of what makes up Folium Biosciences, and we
believe these are vital questions you should be asking any potential partner.
A manufacturer’s reputation depends on its compliance with federal law, the use of best farming practices, and
transparency with seed-to-sale cycle tracking. We’ll discuss the characteristics of good hemp oil manufacturers,
Certificates of Analysis (COAs) data you should be looking for, and how Folium Biosciences can help your
company become one of the top consumer hemp cannabinoid brands in the market!
Truth in HempTM
How to Choose a Hemp-Derived
Cannabinoid Manufacturer
When starting Folium Biosciences, our mission was to help people live healthier and happier lives – a goal you
can’t accomplish with subpar hemp cannabinoid suppliers. Beyond being a trusted source for raw ingredients
and white-labeled finished goods, we also pride ourselves on being a partner from ideation to formulation.
In other words, we have a depth of expertise that allows us to help our customers answer the question, “Is
this possible?” and explore even the most ambitious and creative ideas. We understand these compounds’
intricacies at an unparalleled level, empowering us to help our customers create custom formulations and
establish themselves as leaders in their sector.
With these partnership thoughts in mind, here are the top things to look for in an
hemp manufacturer.
1
Product Quality
There are various factors to consider when it comes to CBD, CBG, or CBN, but
our number one priority is product quality. What you typically see on the market
these days are three main varieties, broad spectrum, full spectrum CBD, and CBD
isolate. Which do you think sounds like a better-quality product? If you said broad
or full spectrum, you’d be right. In a broad and full spectrum product, like those from
Folium Biosciences, CBD’s efficacy is amplified. By using these types of products,
you’re getting all the benefits of hemp as nature intended.
Our unique cannabinoid profile is reflected in our Broad Spectrum 0.0% THC hemp
oil containing all the naturally occurring cannabinoids and terpenes intrinsic to our
genetics. We guarantee 80% or more active CBD in our 0.0% THC-free hemp oil
and over 30 terpenes, among other beneficial molecules.
Isolate, on the other hand, is just as it sounds, isolating only one of those cannabinoids
and removing it from all other components. CBD isolate is CBD in its purest form and
is typically ground and sold as a powder. While CBD isolates might be an efficient
product and sound like the way to go, you’re not getting the best quality or benefits
as you would from a full or broad spectrum solution with all the molecules working
together.
If you want to be the “go-to” for CBD, make
sure you’re partnering with a manufacturer
that produces broad or full spectrum products
because not all hemp is created equal.
2
“Knowing how the hemp is sourced
defines the plant and gives excellent
information on the hemp oil supplier’s
ethical practices. ”
3
How and Where Are They Farming?
Once you have a potential supplier in mind, look at where they sourced their hemp.
Ask questions like:
• Is it grown sustainably using organic practices?
• Are crops grown in accordance with the highest cultivation standard?
• Is this a U.S. farm or cultivated overseas?
• Do they breed high strains of hemp in compliance with USDA and the state
agricultural department?
• Has the soil been tested?
• Are they properly rotating crops?
• Do they have oversight on the farms? Or, do they just purchase biomass off the market?
Knowing how the hemp is sourced defines the plant and gives excellent information on the hemp oil supplier’s
ethical practices. Even state-of-the-art equipment can’t make up for cutting corners with harvests made from
inorganic farm practices.
Here’s how Folium delivers the farmers and harvest you’ll need
• We have been headquartered in La Junta, Colorado, since 2015.
• Our proprietary high cannabidiol CBD / low THC cultivar provides us with a competitive advantage
in the global hemp-derived phytocannabinoid industry.
• Our non-GMO hemp genetics are grown 100% in the USA.
• Folium’s products contain a phytocannabinoid- and terpenoid-rich strain.
• We use sustainable farming practices.
• We also work with the Environmental Protection Agency and the State of Colorado to improve
soil and water quality.
• The integrity of our farming practices is underscored by our perfect track record with the
Colorado Department of Agriculture. Folium has never failed a compliance test. Our fields have
never “run hot” with a THC content of greater than 0.3%.
• We utilize advanced harvesting techniques for maximum efficiency.
• We harvest and extract the complete plant for our staple ingredient, Broad-Spectrum CBD Oil
(0.0% THC).
• We support local farmers and economies.
4
Cycle Tracking – from Seed to Sale
Every minute of a hemp plant’s life cycle denotes critical moments in CBD production. Plants are tested
continuously until they reach the desired maturity of the richest cannabinoid and terpene profile.
That’s why we closely track and monitor our hemp starting in the ground with the soil and the seed
Our tracking system follows the plant through these stages:
• Propagation and Seed Creation
• Cultivation
• Harvest
• Extraction
• Purification
• Distribution
• Sales
These tracking systems often contain a combination of written records and software in a single database
that can be used by cultivators, processors, manufacturers, transporters, and others involved throughout the
process that provides a thorough history of the product. Bottom line, traceability is KEY!
5
The more you know about the plants
used to make your product, the more
targeted approach you can take in
creating products and marketing
them.
6
The Right Licenses and
Certifications
While CBD has been largely unregulated thus far, there are specific regulatory licenses and proper manufacturing
certifications that the best hemp manufacturers will carry. Only the top CBD companies align with these types
of manufacturing facilities. We’re no exception!
Regulatory licenses and certificates will vary from state to state. Trusted hemp manufacturers should be clear
about the regulatory licenses they carry.
A few licenses and certificates to keep an eye out for, which Folium has obtained,
include:
• Good Manufacturing Practices (GMP) Compliant
• FDA Registered Facility
• EU Pharmaceutical Manufacturing Licensing
• ISO Certified Clean Rooms for Processing
• Kosher Certified
• Halal Certified
These regulatory licenses and certificates mean that the equipment is in process preventative control. Passing
a government inspection confirms that all products made answer customers’ and stakeholders’ needs, while
meeting statutory and regulatory requirements related to CBD. From a state, federal, and even worldwide
perspective, we at Folium Biosciences transparently follow all regulatory guidelines.
7
Certificates of Analysis (COAs)
Each CBD oil batch should be consistent. COAs ensure this quality.
These documents provide a thorough breakdown of what is in the
hemp extract they’ll be supplying.
Common inclusions on COAs are:
• Phytocannabinoids (CBD, THC, CBDa, CBN, etc.)
• Terpenes
• Microbiologicals – including mold
• Mycotoxins
• Pesticides
• Heavy Metals
• Solvent
Not only do COAs create transparency, but they also ensure that the product contains exactly what it claims.
A 2017 study found that almost 70% of CBD products sold online aren’t labeled correctly, having considerably
less or more CBD than advertised. Hemp manufacturers should offer the most recent COAs of all products
provided.
As you can see above, COAs are critical, but here are a few other factors that you’ll want to observe. Is the
manufacturer monitoring, measuring, and collecting data daily? Are their ingredients and products fully
traceable? Do they implement out-of-spec investigations if there is a discrepancy? Is the manufacturer
following best practices and staying up-to-date with all regulations? Can they offer that value? And what
are they researching in terms of product development? At Folium Biosciences, we have invested in a full
infrastructure that supports our science, scale, and innovation. It demands and delivers transparency, quality,
and a unique refinement in cutting-edge offerings.
8Ask About the Facility
Because our industry has been so unregulated, it means that oil can be extracted pretty much anywhere, and
no one would know the difference. When researching hemp cannabinoid manufacturers, make sure that the
product they’re offering is made in a legitimate manufacturing facility rather than in someone’s garage or shed.
Folium’s facility can’t be beaten. This summer, we announced the completion of our 110,000-square-foot Pueblo
West build-out. This FDA-registered, state-of-the-art facility is the world’s largest cannabinoid extraction and
purification facility, and it will produce up to 15,000 kg of 0.0% THC broad spectrum CBD oil each month.
Answering the accelerating demand for safe, high-quality CBD product manufacturers worldwide, our plant
has dedicated production lines to meet CBD regulatory requirements in the U.S., EU, Japan, and South Korea.
Most importantly, our facility was purposely built for extraction, purification, and formulation of cannabinoids
and terpenes utilizing our exclusive CO2 technology that delivers the finest hemp-derived, non-psychoactive
cannabinoid products on Earth.
9A Word on the Benefits of Bulk
Material
The ways to take advantage of CBD are nearly endless, but getting started means you will need the right
expertise and experience to build from. The longevity of Folium’s genetic R&D program, for example, and the
resources that our company invests in maintaining the genetic purity of our plants all the way through to our
raw ingredients is a significant competitive advantage.
Folium Biosciences’ CBD oil is one of the few on the planet that can truly be claimed as broad spectrum. We
preserve all present minor cannabinoids and naturally occurring terpenes during our extraction process. Our
bulk ingredients are ideal for formulation and will help create a unique product in the marketplace. Thanks to
our proprietary extraction and purification process, these components together carry a synergistic effect into
any manufactured goods.
Folium Biosciences’ CBD oil is one of the few on the planet that can truly be
claimed as broad spectrum.
10Defining the Difference
There is a big difference between hemp cannabinoid manufacturers and CBD
consumer goods businesses. If you’re looking to purchase CBD oil products
wholesale or for a private label, you are a CBD company. You are looking for a
trusted hemp-derived cannabinoid manufacturer that can help you realize your
company’s strategic goals.
Hemp cannabinoid manufacturers are the ones
that have the technology necessary to extract
CBD oil and utilize all the beneficial molecules
of the entire hemp plant. Depending on the
manufacturing facility, they can run multiple
operations. Understanding these differences is
essential for running your business.
11“Understanding their technology and
extraction methods is vital for your
bottom line, as these resources will
impact the type of products you sell
and how much the CBD oil will cost.”
12More on Manufacturing
Before you get too far into vetting potential hemp cannabinoid manufacturers, figure out what
type of cannabinoid oil products you want to sell. Then determine if their manufacturing facility
can accommodate your requests.
For instance, some companies specialize in full spectrum hemp extracts. That’s where all
cannabinoids remain in the formula, including THC.
Other manufacturing facilities are capable of removing THC. 0.0% THC products, like Folium
Biosciences’, are considered broad spectrum. Broad spectrum CBD oil requires cutting-edge
technology that selectively removes THC.
As previously mentioned, Folium uses supercritical CO2 for extraction
to efficiently produce large quantities of oil, giving us unparalleled
scalability. We utilize liquid chromatography in our purification
process, which gently removes THC while leaving the
broad spectrum profile of non-psychoactive
phytocannabinoids, terpenes, and synergistic
compounds intact.
13Is a CBD Company Different Than a
Supplier?
If you are selling CBD, you are a CBD company. Therefore, some of the largest hemp manufacturers in the world
are also the top CBD companies. However, some hemp manufacturers provide top CBD companies with the
phytocannabinoids necessary to make their own unique product line.
Being this type of CBD company still offers a great experience. That’s why you might be better suited to join
a Wholesale or White Label Program. Within this type of program, hemp suppliers give you the products you
need to run your own CBD business.
You use their products and resources, but it’s your brand name on
the bottle. Your CBD company is free to market what you receive
from your hemp suppliers however you please!
144 Reasons to Choose Folium Biosciences
as Your CBD Supplier – and Your
Hemp Manufacturer
When choosing the right CBD supplier, remember, not all hemp is created equal. It’s a difficult decision, and we
get it. But that’s why Folium Biosciences is here to make your decision a no-brainer.
1. Quality
At Folium, we carefully cultivate and control our broad spectrum CBD at every stage in the growing and
manufacturing cycle – from seed to processing to raw material and finished product manufacturing. Our team
understands the science of superior cannabinoid production at an incredibly in-depth and expert level. Very
few companies have the big-picture perspective, total oversight, and level of transparency across the system
that we do.
Our vertically integrated approach also translates into consistency. The fact that Folium puts out so much raw
material so quickly and incredibly consistently is a huge differentiator for our customers who are introducing
their own product lines.
Folium’s quality is a unique practice:
• World’s first hemp company to be issued Certificate of Free Sale and a Manufactured Food
Establishment License by the Colorado Department of Public Health & Environment
• Setting the industry standard for analytical test methodology
• Full suite of testing at every step of vertical integration process, including biomass, oil, and
finished goods
• Passing all third-party audits by clients
154 Reasons to Choose Folium Biosciences
as Your CBD Supplier – and Your
Hemp Manufacturer (Continued)
2. Science
For Folium, the difference starts in the ground. We began our breeding and growing sciences with a singular,
proprietary hemp strain. Since then, Folium’s hemp strains have evolved significantly by introducing other
genetics from a wide range of diverse hemp strains. This approach strengthens our proprietary strains by
keeping the genetics robust and healthy.
• Patented and proprietary extraction and purification processes
• Leading clinical trials with folium biosciences products
• Folium Biosciences clinical incubator
• Team of FDA investigators answering the critical questions for the next evolution in
cannabinoids
At Folium, we believe in the power of cannabinoids and actively proving the benefits for the entire industry to
prosper.
3. Innovation
When it comes to quality, from seed to sale, Folium never stops working to deliver the world’s most advanced
0.0% THC Broad Spectrum CBD today and making critical investments in innovation to deliver the ground-
breaking hemp-based products of tomorrow. Your customers want a go-to hemp product for every part of their
day, and with a Folium partnership, they will find it.
The Best in Bulk: Our dedicated R&D team offers customize bulk ingredient solutions tailor-made for every
end use.
164 Reasons to Choose Folium Bioscienc-
es as Your CBD Supplier – and Your
Hemp Manufacturer (Continued)
Broad Spectrum CBD Oil (0.0% THC)
Our Broad Spectrum CBD Oil (0.0% THC) contains naturally occurring cannabinoids and terpenes found in
our hemp genetics. With more than 80% CBD, the 0.0% THC oil uses the intrinsic synergistic properties of our
unique cultivar. The extraction and purification process uses a proprietary technology that preserves terpenes
and plant lipids, while eliminating unwanted Δ9-THC, waxes, and chlorophyll. A rigorous quality control and
testing regimen are followed to ensure that critical attributes such as taste, color, potency, and purity consistently
meet cGMP and customer requirements. We can dilute our standard oil to your desired potency.
Full Spectrum CBD Oil
Our Full Spectrum CBD Oil is made with naturally occurring cannabinoids and terpenes found in our hemp
genetics.
Water-Soluble Liquid
Our Water-Soluble Liquid (WSL) formulation is developed through our proprietary emulsion technology.
Available in 35% CBD and designated for use in cosmetic products, Folium’s proprietary water-soluble
liquid is a finely engineered formula that uses optimized composition and a unique manufacturing process.
174 Reasons to Choose Folium Bioscienc-
es as Your CBD Supplier – and Your
Hemp Manufacturer (Continued)
Water-Soluble Powder
Our Water-Soluble Powder (WSP) formulation is developed through our proprietary emulsion technology.
Available in 20% CBD and designated for use in foods that need uniform dispersibility in a hydrophilic medium,
such as ready-to-drink beverages. This formulation has been designed for immediate dissolution in water
before use and for the manufacturing of semisolid and solid products.
Hydro PCR
Our Hydro PCR formulation is developed through our proprietary emulsion technology. It is available in 4%
CBD and designated for use in topicals and cosmeceutical applications. It is made with Broad Spectrum CBD
Oil that is rich in phytocannabinoids and contains reduced amounts of natural surfactants. The manufacturing
process uses technology that incorporates our Broad Spectrum CBD Oil (0.0% THC ) into nano-emulsions
with a droplet size ofFolium Biosciences is unlocking the full
potential of hemp and is committed
to delivering highly refined 0.0% THC
Broad Spectrum Oil with transparency,
excellence, and expertise you won’t
find anywhere else in the market.
19Ready to Partner?
The best part of partnering with Folium Biosciences is that the hard part is done. We have all of our licenses
and certificates in line, our COAs are on hand for the ultimate transparency, and we are seasoned experts with
our full seed-to-sale cycle. Now the fun is up to you. Have you been dreaming up a possible new formulation?
Want to see your brand on something already done? Then let’s get started. With Folium Biosciences as your
CBD supplier, get ready to become an industry leader. Now it’s time to make that vision happen.
Contact your Folium representative or get in touch with one of our specialists by
calling 719-574-2159 or by emailing Hello@FoliumBiosciences.com.
20615 Wooten Road, Suite 110, Colorado Springs, CO 80915
FoliumBiosciences.com
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