MRSA and Staph Infection Research
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MRSA and Staph Infection Research This product is for sale ONLY outside the USA for the treatment of MRSA. The FDA has not yet released a monograph authorizing products to be sold in the USA with claims regarding the treatment of MRSA. © Phillips Company 2010 MRSA Page 1
Contents Purpose ....................................................................................................................................................... 4 Foreward .................................................................................................................................................... 4 Tetracycline-ABC is not marketed as a treatment for MRSA or staph infections in the USA; only outside the USA ................................................................................................................................... 4 Section 1 ............................................................................................. 4 Introduction....................................................................................... 4 Tetracycline-ABC is more effective against MRSA and staph than against any other bacteria for which TABC has been tested .............................................................................................................. 5 Tetracycline-ABC attributes ..................................................................................................................... 5 Section 2 ............................................................................................. 6 Pam’s MRSA (head and neck) treated successfully ....................... 6 Pam used Tetracycline-ABC to treat a staph infection on the neck, scalp and side of face .................. 7 © Phillips Company 2010 Improvement noted; bumps/lesions less prominent and less red (less inflammed) ................................ 8 Successful MRSA treatment ................................................................................................................... 11 Section 3 ........................................................................................... 12 Tanya’s MRSA lesions treated successfully .................................. 12 Before TABC use .................................................................................................................................... 13 Before and after photographs ........................................................ 13 Day 7 ........................................................................................................................................................ 13 Day 20 (AFTER) ...................................................................................................................................... 13 Tanya’s medical history included MRSA infections in August, 2010. ................................................... 14 Tanya developed new skin infections (January, 2011) before using TABC .......................................... 16 Report received from Tanya on Day 3 (1/13/2011) ................................................................................ 27 Report received from Tanya on Day 4 (1/14/2011) ................................................................................ 27 Tanya’s diet and medication report on Day 4: ....................................................................................... 32 Tanya’s diet .............................................................................................................................................. 32 Tanya’s food supplement program .......................................................................................................... 32 Tanya’s medication (as of Day 4) ............................................................................................................ 32 Tanya also used Tetracycline-ABC on a cold sore ................................................................................ 32 Before TABC use .................................................................................................................................... 39 Day 7 ........................................................................................................................................................ 39 Day 10 -- Tanya’s report from the clinic ................................................................................................. 45 Section 3 ........................................................................................... 46 Tanya -- Can systemic MRSA be cured with a topical medicine? 46 Offer to extend Tanya’s field test ........................................................................................................... 47 Tanya’s decision: Extend the field test .................................................................................................. 49 MRSA Page 2
Consultation with Tanya’s health care provider, 1/20/2011. .................................................................. 50 Test plan to treat systemic MRSA using a topical mediction ................................................................ 50 Protocol details -- Systemic MRSA treatment began 1/21/2011 .......................................................... 52 Report from Tanya on the first day of the systemic MRSA treatment (1/21/2011) ............................. 52 Before TABC use .................................................................................................................................... 59 Day 7 ........................................................................................................................................................ 59 Day 13 ...................................................................................................................................................... 59 Answers from Tanya about SYSTEMIC MRSA treatment (Day 14) .................................................. 60 Tanya’s blood was culture-tested and showed no detectable level of MRSA after 10 days of TABC topical treatment ................................................................................................................................ 67 Treatment timeline and tentative conclusions ........................................................................................ 68 Before TABC use .................................................................................................................................... 72 Before and after photographs ........................................................ 72 Day 7 ........................................................................................................................................................ 72 Day 20 (AFTER) ...................................................................................................................................... 72 Tanya’s case -- summary and tentative conclusions .............................................................................. 73 Section 4 ........................................................................................... 74 © Phillips Company 2010 Lawrence -- Can presumed systemic MRSA be cured with a topi- cal medicine? ............................................................................... 74 Can presumed systemic Lyme disease be cured with a topical medicine? ..................................................................................... 74 Lawrence (Tanya’s husband) was treated with TABC for topical MRSA infections ............................ 75 Lawrence had Lyme Disease .................................................................................................................. 75 Report about LP’s lesion; from Lawrence’s wife ................................................................................... 77 Treatment timeline and tentative conclusion .......................................................................................... 83 Assessment of Lawrence by a microbiologist ........................................................................................ 84 Lawrence had Lyme Disease .................................................................................................................. 84 Lawrence’s case -- summary and tentative conclusions ........................................................................ 85 MRSA Page 3
Section 1 Introduction Purpose The purpose of this document is to report research results. Foreward Before reading this document, please read the parent document: www.PhillipsCompany.4T.com/CC.pdf Think of the field tests reported here as informal (not clinical) tests. These tests were carried out under informal conditions. © Phillips Company 2010 The ingredients in our tetracycline products include ONLY ingredients that can be ob- tained over the counter (OTC) without a perscription. In some cases (reported in this document), discoveries were made. This often happens when someone is given a medication without formal directions for use, except that it should be used only on the skin. Occasionally, the benefit of the remedy is found to be useful for conditions not previously anticipated. The TABC formulations used in these tests were made available to the users at no cost. No product was offered for sale. No product was sold during these evaluations. We appreciate any feedback. Contact hp@valliant.net via email. Tetracycline-ABC is not marketed as a treatment for MRSA or staph infections in the USA; only outside the USA The reason for this is that the FDA has NOT approved tetracycline or Tetracycline-ABC for sale as a treatment for MRSA or staph infections. Nothing in this document (or any document or web site sponsored by Phillips Company) shall be interpreted as claiming or implying that our products are for sale in the USA for use as treatments for MRSA or staph infections. The only way that any Phillips Company products, including Tetracycline-ABC, can be used for treatment of MRSA or staph infections is if a physician elects to do that, based on NO marketing or sales of our products for that purpose in the USA. MRSA Page 4
Tetracycline-ABC is more effective against MRSA and staph than against any other bacteria for which TABC has been tested Best © Phillips Company 2010 For MRSA and staph bacteria, the TABC kills the bacteria over an area (ZOI) which is 22 to 23 times larger than the area (ZOA) where the TABC is applied. This AMPLIFIED BIO- LOGICAL COVERAGE is desired because this special formulation carries the tetracycline deep into the skin when it is rubbed in. Tetracycline-ABC attributes √ Tetracycline-ABC is a very broad-spectrum topical antibiotic. It is an effective bacterial agent for every harmful bacteria for which test data has been acquired during all tests and evaluations. √ TABC is “skin colored” and is transparent when applied to the skin. The color is yellow-orange which blends well into the color of the skin -- and it absorbs readily into theskin. Minor precaution is needed to prevent staining of clothing if the area is not ban- daged. MRSA Page 5
Section 2 © Phillips Company 2010 Pam’s MRSA (head and neck) treated successfully Note: Confidential and personal information was redacted before public access to this report was enabled. MRSA Page 6
Pam used Tetracycline-ABC to treat a staph infection on the neck, scalp and side of face Pam, a 60-year-old female, turned to Before Tetracycline-ABC after using other antibiotics (1/6/2011) unsuccessfully. Before using TABC, her physician perscribed clindimycin, doxycycline, keflex and other medications, but © Phillips Company 2010 the staph infection persisted. The diagnosis of her condition was “staph infection.” The diagnosis was not explained as a MRSA Before infection, although a MRSA infection is suspected because the condition was resistant to other perscribed antibiotics. The magnified view at the right shows the lesions on her scalp. Because the condition involved both the scalp and the neck, allergies to soaps and shampoos were ruled out as the cause. MRSA Page 7
Improvement noted; bumps/lesions less prominent and less red (less inflammed) Day 4 Day 4 © Phillips Company 2010 Day 4 MRSA Page 8
Pam’s skin condition extended from her scalp Before down to her neck. (1/6/2011) This is a “difficult-to- cure” condition. A physician’s diagnosis was a bacterial infection. MRSA infection is suspected because the condition was resistant to other perscribed antibiotics. © Phillips Company 2010 The magnified view below shows the lesions on her neck. Before (1/6/2011) MRSA Page 9
Report from Pam: “I am on my 3rd day of Tetracycline-ABC use. Day 3 The good news is that my face has cleared significantly. My scalp 1/17/2011 too. However, I am still having a few new breakouts and I have run out of the Tetracycline-ABC. The improvement on my face is just terrific! I feel that this will do the job!!!! It is such a relief. I was very scared. Thank you so much. Blessings, Pam” Day 3 © Phillips Company 2010 1/17/2011 MRSA Page 10
Successful MRSA treatment Day 4 Day 4 Day 4 © Phillips Company 2010 Day 4 Report received on DAY-10, 1/24/2011: When I treated the bumps in a clustered area, and then stopped, I broke out along the outer perimeter of the area. This time when I received the second shipment of TABC, I treated my entire scalp. That seems to have calmed things down. No new outbreaks in the past 24 hours, since I treated my entire scalp. The TABC treatment is also drying up the few outbreaks on my face as well. MRSA Page 11
© Phillips Company 2010 Section 3 Tanya’s MRSA lesions treated successfully Note: Confidential and personal information was redacted before public access to this report was enabled. MRSA Page 12
Before and after photographs Before TABC use Day 7 Day 20 (AFTER) Day 20 Ear Day 0 Day 7 Ear Ear Day 7 Chest Day 20; Chest; same as Day 0 Day-7; totally clear. Chest © Phillips Company 2010 Day 20 Day 7 Day 0 Hip Hip Hip Day 0 Day 20 Day 7 Lower Lower Lower spine spine spine Day 7 Day 0 Day 20 Front Front Front MRSA Page 13
Tanya’s medical history included MRSA infections in August, 2010. Tanya began using TABC on January 10, 2011. These photos document the medical history of her MRSA infection and surgery 4 months before she began using TABC. “Dr. Phillips, for your records, here is the only picture I BEFORE have of pre-surgery MRSA, taken the (Photo taken August 2010) day before I went to the clinic for culture tests and 2 clindamycin (300mg each) shots. I think this © Phillips Company 2010 is a picture of pretty classic MRSA pre- sentation. The boils started out as just a pimple around a hair follicle. Thought your test results would be more 'complete' with this 'before' picture. Thanks, Tanya” BEFORE Tanya’s report dated 1/10/2011: “I had MRSA surgery which was performed August 24, 2010. This site reactivated (became inflamed/infected) just 2 weeks ago.” MRSA Page 14
Dr. Phillips, here is a picture taken 12.25.10, front sore along a 17 year old surgery scar line, (the original surgery was for a fibroid removal, it was on a stalk, was removed thru this scar, when the surgeon stitched it closed, she caught the abdominal wall lining in with the skin. 6 months later I had 'hernia' surgery to correct it -- Oregon health plan. The sore started with just a pimple-like eruption. it started on 11.7.10, and grew to this size by Dec. 25, 2010. I hope this helps your field study be more complete. Thanks, Tanya BEFORE TABC use © Phillips Company 2010 BEFORE TABC use This photograph was taken 3 weeks before Tanya began using TABC. MRSA Page 15
Tanya developed new skin infections (January, 2011) before using TABC Tanya: “Here is a picture that I BEFORE took last Saturday (January 1, TABC 2000) as the MRSA rash was (1/1/2011) worsening and starting to weep really bad. This photo was taken before I was given clindamycin shots and capsules.” © Phillips Company 2010 BEFORE The magnified photo at the left shows TABC the “cluster” nature of the bumps and lesions. This is characteristic of a (1/1/2011) bacterial infection that results from enhanced bacterial growth following a quorum-sensing event. Treatment successful at decreasing the bacteria concentration (colony-forming unit concentration) can often lead to a smoother (less clustering) appearance, followed by resolution of the condition. MRSA Page 16
Before starting the use of TABC. Photo taken Saturday (January 1, 2010) © Phillips Company 2010 BEFORE TABC (1/1/2011) The “weeping” nature of Tanya’s skin lesions is often associated with minor lesions, as shown circled in the magnified photo. MRSA Page 17
Tanya had been a MRSA patient for several months before she began using TABC. The red (inflamed) area around the surgical site suggests a lingering infection; probably MRSA. This type of infection, because of the previous surgery, is an indication that the MRSA infection is deep; not just on the surface of the skin. Left hip from MRSA scar, where the surgeon 'cored' me Aug. 25, 2010. BEFORE she © Phillips Company 2010 began using TABC. This photo was taken on 1/7/2011. BEFORE TABC (1/7/2011) MRSA Page 18
BEFORE she began using TABC. This photo was taken on 1/7/2011. © Phillips Company 2010 BEFORE Tanya: “I had two MRSA scars from my TABC surgery which was (1/7/2011) performed August 24, 2010. These sites reactivated (became inflamed/infected) just 2 weeks ago. One scar is small (at top), other scar is on right side, about 3" lower.” Note the open lesion (circled). MRSA Page 19
BEFORE she began using TABC. This photo (Jan 1) can be compared to the Photo was taken on 1/1/2011. photos below (Jan 7) to show how the lesions became more inflamed and began weeping over a 1- week period of time. © Phillips Company 2010 1 week Tanya: “ About 2 weeks ago before this photograph was taken, it started to weep.” “I taped the open lesion with a cotton guaze pad and used white paper tape to cover it. Where the white paper tape was, every hair follicle got red and then the follicles started to weep.” BEFORE TABC (1/7/2011) MRSA Page 20
BEFORE she began using TABC. This photo was taken on 1/7/2011. © Phillips Company 2010 BEFORE TABC (1/7/2011) Tanya: “This rash, on my chest, began as one red pimple, beginning January 3, 2011; and has advanced to this rash in one week.” MRSA Page 21
Physician’s decision: Tanya received Tetracycline-ABC and began using it on January 10, 2011 (Day 1). On that day she was also seen by her physician. The patient and the physician, by mutual agreement, suspended other treatments and prescribed standard tetracycline to be taken orally, 4 times each day. The purpose of this was to combine the TOPICAL treatment (Tetracyline-ABC) with ORAL treatment, with the hope of fighting the MRSA with a combined effect. The following photographs were taken AFTER Tanya began using TABC Day 2 Day 2 © Phillips Company 2010 (1/12/2011) Report received from Tanya on Day 2: “Here's my left ear, 40 hours after the first use of TABC; after a total of 8 applications of Tetracycline -ABC.” MRSA Page 22
Dr. Phillips, Here’s a photo of my chest. Notice how much the rash had spread by Day 2 Monday, the individual blisters that formed on each (1/12/2011) hair follicle are drying up and stopped weeping. The little crust tops are coming off. The redness has faded considerably. Thanks so much for sending the medicine. I had been on clindamycin for 6 days, and the sores were not responding, in fact my chest and ear rashed out while I was taking the clindamycin. © Phillips Company 2010 The Dr. K.C. prescribed oral tetracycline, 500mg. 4X daily, for 10 days. I’ve taken 8 doses of that as prescribed. unfortuneately, my outer vulva is starting to exhibit Day 2 and feel like candida infection is taking root, just (1/12/2011) like last time in Sept. —I stopped all the herbs I was taking for that and for the hot flashes/night sweats. I hate the fluconazole that he prescribed for the candida. After tomorrow, I may cut back the oral dose of tetracycline to 3X day. I feel really grogged out and hate the candida I feel coming on. In my opinion, taking internal antibiotics for a skin condition is about the goofiest way to treat it! If you’ve used TABC for toe fungus, could I put some on my outer vulva, to treat the candida patches (fungus)? With gratitude, Tanya MRSA Page 23
Dr. Phillips, Here is base of my spine, 40 hrs. later, and after 8 applictions of Day 2 TABC. The weeping has stopped, thickened skin has (1/12/2011) started to crust and come off as dry flakey skin. Also please note, I’ve been applying the TABC to the purple spots, as well. I can’t be sure but I think they are lightening a little too. Those purple spots were from the original infection in August. I had put tea-tree oil on them in September and they © Phillips Company 2010 lightened a little, but not like the past 40 hrs. Tanya Day 2 (1/12/2011) MRSA Page 24
Day 2 Dr. Phillips, this is my left hip. (1/12/2011) The red circle has faded a little, the blistering rash has subsided, old crusty skin has flaked away, looks better, after 40 hrs. and 8 applications of TABC. Tanya © Phillips Company 2010 Day 2 (1/12/2011) MRSA Page 25
Dr. Phillips, here’s my front side, after 40 hrs. and 8 Day 2 applications of TABC. The rash is subsiding, little (1/12/2011) blisters are drying up, notice where old scar line is, can see the purpleness of the MRSA. Above the scar line, the skin is crusty and starting to flake away. I think this one spot is still the worst, because it was so large, initially. The sore above my lip, below nose, has crusted also. When the PA saw that one on Monday, he thought it looked ‘herpetic’ —which i have had herpes sores before, and I was upset 3 days before the sore errupted. (usually that’s how it works for me...) regardless, I’ve put © Phillips Company 2010 the TABC on it and it dried up the blisters. For the record, I had impetigo (on my lips) when I was 4 yrs old; I know that’s a staff infection too, Tanya Day 2 (1/12/2011) MRSA Page 26
Report received from Tanya on Day 3 (1/13/2011) Dr. Phillips, My progress is continuing. I sure appreciate the improvements I am experiencing. Thanks, Tanya Report received from Tanya on Day 4 (1/14/2011) Dr. Phillips, As you know, I recieved the first medicine on Monday p.m. and applied 2x that evening. Today would be day 4, and I have applied the tetracycaline ABC 18 times prior to these photos. I am keeping a log of when I apply the topical medicine and when I take the oral tetracycaline as well, I can set this up on a chart or timetable for you, if that would help your test results. The left ear was the most recent sore to errupt. As you can see from this © Phillips Company 2010 photograph, it is still alittle crusty, but healthy pink skin is showing through. The pain has subsided; the weeping has stopped; the swelling has gone down, and I can wear my glasses again! That is greatly helping my attitude to improve. Thanks, Tanya Day 4 MRSA Page 27
Dr. Phillips, Here is my left hip. It is Left hip obvious that although there is Day 4 alittle crusty skin flaking off, it is greatly improved. The skin around the scar has l i g h t e n e d considerably; the center of the scar has lost its angry redness, and the blistering has © Phillips Company 2010 a l m o s t disappeared. It is looking better. Thanks, Tanya Day 4 MRSA Page 28
Dr. Phillips, Here is the sore on the base of my spine. I hope this isn't too close. The redness has faded; the blistering has gone, and new pink skin is showing. The crusty skin has flaked off. Note the large MRSA surgery scar (from the surgery last year). It had a bump raised in it's left center when we started Tetracycline-ABC on Monday. Today, the bump has shrunk by half (half the original size). Although it is still there, it has gone from the size of a bean to the size of a small pea. The weeping has stopped. I can feel the bump is less sensitive, because this when I awakened this morning, I was lying on my back -- I haven't done that for 6 months! That bump inside the scar tissue area had pressed on the base of my spine and that made it uncomfortable for me to lean back in a chair or car seat; or to lie flat on back. Thanks, Tanya © Phillips Company 2010 Base of spine Day 4 MRSA Page 29
Dr. Phillips, Here is a photo of the MRSA lesion on my Chest chest. This rash and the blistering spots were the Day 4 second-to-last erruption. As you can see, it is fading considerably. Although one can still see the individual hair follicle blister sites, the blisters are gone, the blisters have stopped weeping and the crusty little tops have all come off. It looks much better and it © Phillips Company 2010 doesn’t hurt at all today. Thanks, Tanya Chest Day 4 MRSA Page 30
Dr. Phillips, Here is my front sore on the old scar line. That Day 4 scar is easier to see today. One can see the MRSA sore where it popped up on one end of the scar line. The redness has lightened, there is still some crusty spots, but the outlying blisters have healed considerably. The angry redness has turned to a lighter pink color. The skin is smoother, softer; not thick and leathery feeling like it was on Monday. The © Phillips Company 2010 weeping has stopped and I am pleased with the results. In gratitude and Light! Tanya Day 4 MRSA Page 31
Tanya’s diet and medication report on Day 4: Tanya’s diet I am still on this strict diet: organic food only, herb tea, oatmeal or cream of rice each morning, fresh garden salad for lunch, and bean, split pea, lentil, or brown rice soup for supper. My only snack food is unsweetened yogurt with cashews or almonds, and ground golden flax meal. Tanya’s food supplement program “I have been taking 3 capsules (40 billion colony forming units per capsule, of Probioitics), every night, usually at 1 a.m., 3a.m. and 5 a.m., dividing a liter of water with doseages. This is to help prevent the candida from taking root. I am trying to take the Probiotics capsules © Phillips Company 2010 as far as possible (time separation) from the oral antibiotics, in the night, with plenty of water to help keep that darn candida from rooting in. Last September when I was previously on Clindamycin antibioitics, I had candida VERY BAD...even though I wasn’t eating/drinking any sugar, cafeine, gluten, or alcohol.” Tanya’s medication (as of Day 4) “I am still taking oral tetracycline, but today I only took 3 doses instead of 4 doses daily. I had been on Clindamycine for 6 days before Monday, then switched to Tetracycline, oral 4X daily. Candida was visiting my outter vulva, so I cut back on the oral dose, from 4X to 3X per day. That makes me having been on oral antibiotics for 10 days total.” Tanya also used Tetracycline-ABC on a cold sore Cold sore Report from Tanya on Day 4: “If Tetracycline-ABC works on herpetic sores, like the one I have on my upper lip (under nose area), perhaps the TABC works because herpes is a virus, hiding in a bacteria... That sore on my upper lip/below nose area, has crusted, peeled and almost faded. If it is a herpes sore, for me they have a life span of about 10 days, going thru the blister, drying up, cracking and healing process. This sore has crusted, dried, and new supple skin is already showing through after using Tetracycline-ABC for only 4 days. MRSA Page 32
Dr. Phillips, This is 'Day 7', left ear. I didn’t want to run out of the Tetracycaline-ABC, so I reduced the # of applications from 5 applications/day (Friday, January 14th) to 4 applications/ day (Saturday, January 15th) to 3 applications/day (Sunday, January 16th). These photographs were taken at noon, after just 1 application this morning. I am amazed at the healing process! This morning when I awakened, I felt different. It is difficult to describe being sick with MRSA for 6 months, and then feeling not so sick. It is like I have to learn how to live again; learn to look ahead and live life like I did before contracting MRSA. I have been so ill for so long that it seems foreign to feel normal again. I am still taking 3 oral tetracycaline doses per day. Thanks, Tanya © Phillips Company 2010 Day 7 1/17/2011 MRSA Page 33
Dr. Phillips, Here is pic of my left Day 7 hip, Day '7'. Please note how the red circle has diminished in size, and 1/17/2011 the color of the circle of inflamation is fading. The surgical scar at the center of the circle is not so tough and leathery. The skin on the scar tissue has started to flake off and is a bit itchy, like new 'good' skin is growing underneath. Almost all the blistering and bumps have gone. The skin looks like its really improving. Thanks, Tanya © Phillips Company 2010 Day 7 1/17/2011 MRSA Page 34
Dr. Phillips, Here is the photograph of the base of my spine, 'Day 7'. By my estimation, this is after 29 applications of Tetracycaline-ABC. Although the MRSA scars are still red and skin is flaking from them, the surrounding skin is healing well. the blisters, bumps, and angry red skin has faded. The largest MRSA scar, at bottom of the photograph, had a bean- sized bump in its center when began treatment. As of today (Day 7) that bump has shrunk from bean sized, to pea sized and perhaps even smaller. I can almost lay on my back comfortably for the first time in 6 months. I was unable to ride in a car seat or drive, because I couldn't scoot back in the seat, now I am gingerly sitting back in a normal sitting position! Scars from previous surgeries Day 7 1/17/2011 © Phillips Company 2010 Planned experiment: One of the worst concerns for any MRSA patient is "will the bad sores come back?" If you compare this photograph with my original “BEFORE” photograph from August 24th, 2010, you will see many small purple spots on my bottom. When I get more Tetracycaline-ABC (shipment expected tomorrow), I plan to put the TABC liquid on the many small purple spots you can see here. To me, these seem to perhaps represent the areas that could be future bad spots (MRSA infections). I plan to see if the TABC might be effective at fading them away as well. Thanks, Tanya MRSA Page 35
Dr. Phillips, This is the photograph of my chest on Day'7'. As you can Day 7 see, the MRSA rash has almost completely faded away. 1/17/2011 Thanks, Tanya © Phillips Company 2010 Day 7 1/17/2011 MRSA Page 36
Dr. Phillips, Here is the photograph of the MRSA lesions on my lower abdomen, Day '7'. This is the bad spot that wasn't even an issue at the time of my original MRSA infectons last year, nor was this area infected with MRSA at the time of the original GYN surgery years ago. The bad spot became infected with MRSA around mid-October, 2010. By that time, I had been sleeping and lying on my stomach for almost 3 months because of the infection on my lower spine. I was having bad night sweats and hot flashes. © Phillips Company 2010 The area on my chest and this area (lower abdomen) were probably not getting adequate air. These 2 areas were sweaty, because the weather was very humid and muggy and hot at that time of year where I live. I think the hot/humid skin was one reason why I developed these bad spots on my chest and on my lower abdomen. The old scar line had always been an unusual spot, with abnormal sensations -- and the thread (suture), used by the surgeon kept coming to the surface through little pimples. This happened for years after the surgery, along the 17-year-old surgery scar. MRSA Page 37
As you can see, the blistering is healing, and the skin has taken on a pale, better color. Some skin is still flaking off and this spot seems to be the slowest one to come around. Day 7 (1/17/2011) Please see note below. © Phillips Company 2010 Before I began using TABC, this spot was so big and scary. Now this spot looks better and feels better "underneath it". Thanks, Tanya Note: The scar line is shown as a dotted line. This scar, from a surgery 17 years earlier, became MRSA infected recently, and was the most-seriously infected lesion, compared to other lesions at other body locations being treated simultaneously. MRSA Page 38
Before TABC use Day 7 Day 0 Day 7 Ear Ear Day 7 Day 0 Chest Chest © Phillips Company 2010 Day 7 Day 0 Hip Hip Day 0 Day 7 Lower Lower spine spine Day 7 Day 0 Front Front MRSA Page 39
Dr. Phillips, Today, my left ear was itching after my shower. I thought it was itching because it was healing and new skin was Day 9 growing underneath. Where I might have scrubbed it a little too zealously, I noticed 1/19/2011 three blisters in the shell of my ear. They itched and unconsciously, I touched them and they popped, oozing a little fluid and light colored blood. Thanks, Tanya Note: Release of liquid is believed to be a good step in the healing process. © Phillips Company 2010 Day 9 1/19/2011 MRSA Page 40
Dr. Phillips, There are no blisters or bumps. This Day 9 looks much better than it looked on 1/19/2011 previous days. The color is returning to normal. The skin still has a few flakes, but the little blisters are drying up nicely. Thanks, Tanya © Phillips Company 2010 Day 9 1/19/2011 MRSA Page 41
Dr. Phillips, This is photograph of my left hip where a MRSA infection resulted in a previous Day 9 surgery and a scar. It is alittle itchy today as well, but I dont 1/19/2011 see any blistering coming up, nor any bumps. The angry red circle has faded but still evident. Did I ever mention that this MRSA wound was the deepest, although it wasnt the largest? Thanks Tanya © Phillips Company 2010 Previous surgery and Day 9 a scar 1/19/2011 MRSA Page 42
Dr. Phillips, Here is a photograph of where the lesions were, on my chest, I can longer Day 9 see any rash, blisters, bumps, or evidence of the infection that was so prominent 9 days 1/19/2011 ago. This could be the last photograph that I will send of this area, unless you need it. Thanks, Tanya © Phillips Company 2010 Day 9 (1/19/2011) No evidence of infection. Appears to be totally healed. MRSA Page 43
Dr. Phillips, This is the photograph of the area at the base of my spine. Day 9 There is a little purple bump, in center of the scar from a previous surgery. This was a 1/19/2011 surgical treatment for MRSA several months before I began using TABC. This spot has scabbed over since yesterday. It is probably much the same as the ones on my left ear. © Phillips Company 2010 Day 9 1/19/2011 MRSA Page 44
Day 10 -- Tanya’s report from the clinic Today, I went to the clinic. Dr. KC saw me and was very excitied and encouraged by my MRSA healing progress. He was excited by how the blistering rash had healed. He had a student in the office with him. I showed them the BEFORE pictures, and then showed them my healing sores; They both were amazed. He read the email you had sent to me, about the request for blood tests for furthering the field test. That's when he decided to call you and make sure he got the right one. He wrote up the script for the blood culture test, which the clinic couldn’t provide. He took the urine CFU test, as it only cost $2 at the clinic. I had printed off 4 pages from the 50 page online pdf document (the intro page, 2 graphs, and the list of bacteria kill ratios) hoping to spark his interest. He said I didnt have to continue with the oral tetracycaline. I went to the local hospital and they drew the blood for the culture tests. They said it would take 48 hrs for results, so I will return on Monday to pick up the records. The nurse at the clinic who took my temperature via my left ear remembered how bad it had © Phillips Company 2010 looked when she had seen it previously, on Monday, January 10th. She was so happy to hear how well the topical TABC worked. The nurse who drew the blood was interested in what the blood was for, and she became very interested when I explained. It’s no wonder, because there are so many people in this county who have MRSA. I am feeling so much better! There is hope in my heart that there will be life after MRSA! Thanks so much. I really appreciate it! Tanya MRSA Page 45
Section 3 Tanya -- Can systemic MRSA be cured with a topical medicine? © Phillips Company 2010 Topical MRSA is a skin infection. Systemic MRSA is when MRSA bacteria is in the blood stream, affecting the entire body. This is the first attempt to treat presumed systemic MRSA with a topical medicine. The results shown here are very encouraging. Note: Confidential and personal information was redacted before public access to this report was enabled. MRSA Page 46
Offer to extend Tanya’s field test Tanya -- If you would like to extend the current field test, we can try using TABC to drive the MRSA totally out of your body. On 1/17/2011 1:21 PM, Tanya wrote: > One of the worst concerns for any MRSA patient is "will the bad sores come © Phillips Company 2010 back?" if you compare my original photograph from aug. 24, 2010, you will see many small purple spots on my bottom. When I get more tetracycline -ABC, I plan to put the liquid on the many small purple spots you can see here. To me, these represent the sores that could be future bad spots. I'd like to see if the TABC would be effective at fading them away as well. > Thanks, Tanya You are right, to expect problems in the future. I suspect you have what is called "systemic MRSA" which means that it is probably in your entire system ( in your bloodstream), where it can live for weeks or months before it causes other infections -- probably starting with another round of skin infections. When that happens, those new sores can be treated with TABC, and you should expect similar results. But, there is another option if you want to extend the ongoing field test. The option is for us to try using TABC to drive the MRSA totally out of your body. This would involve two blood tests (to be done by your physician) and the use of TABC topically (no shots; no pills). If you want to do this, please let me know so we can make a plan for that. MRSA Page 47
The way it is now, in the medical world: Modern medicine has a difficult time treating and curing MRSA. (You already know that.) In the USA, more people die each year from MRSA infections than the number of people who die from AIDS each year. (You probably know that, too.) Our field tests continue to show that we have an effective MRSA treatment, using TABC. In fact, we have never seen a failure of our field testing of TABC. But the medical professionals don't yet know very much about TABC -- it is a new drug that seems much better than any drug currently in use, and side effects are almost non-existent for most people. If you ask your physician to cure you of SYSTEMIC MRSA, you will probably be hospitalized and given VANCOMYCIN with an IV tube in your arm. VANCOMYCIN is the strongest and © Phillips Company 2010 most effective drug currently being used by modern medicine, but it is effective (successful) only about 40% of the time, and it often causes first-stage kidney failure... (THAT is the reason why most physicians reserve the use of VANCOMYCIN for use as the drug of last resort, when MRSA infection becomes a life-or-death matter.) I think we have a good chance of curing you of MRSA throughout your system, including your bloodstream, by applying TABC to your skin -- no VANCOMYCIN, no bad side effects, no shots and no pills. Here is how we would do that: 1. You would ask your physician to do a blood test and ask for a MRSA CULTURE TEST to be done by the lab. Ask for a CFU count to be provided by the lab to your physician. This establishes whether you have MRSA bacteria in your blood. I'm almost certain that test will be "positive" saying that you have MRSA in your blood. 2. We will supply you with TABC for continuing use, much like you have been using it, but we recommend that you use TABC on your neck and your wrists. These are places where blood vessels are near the surface of the skin. We expect TABC, using TRANSDERMAL delivery, to fight the bacteria in your blood vessels. This is because we believe TABC has a higher transdermal efficiency than any other antibiotic in the world. 3. After using TABC on your neck and wrists for 2 or 3 weeks, you will ask your physician to REPEAT the blood test. This would be an identical blood test (identical to MRSA Page 48
what was done in Step 1 above). Your physician would order a MRSA CULTURE TEST to be done by the lab. Ask for a CFU count to be provided by the lab to your physician. This establishes whether you have MRSA bacteria in your blood. We believe there is a good chance that the test will show that you NO LONGER HAVE MRSA IN YOUR BLOOD. Please let me know if you would like to extend the ongoing field test with the goal of getting the MRSA out of your body completely. If this extended field test is successful, you should then be MRSA-free. If you choose to end the field test when the skin lesions are healed, we will be pleased to do that because you have been an EXCELLENT field test subject and your feedback comments and photos are so good that your case will be studied by physicians for years to come. So, the choice (whether to extend the field test) is totally your choice. If you want to extend the field test, the first blood test should be done very soon -- in the next 2 or 3 days if you can get an appointment with your physician. The reason is that we © Phillips Company 2010 want the first blood test results only 2 or 3 days after all the open lesions have stopped weeping. I think we are already at that stage, so "the sooner the better" is my recommendation for the first blood test. Please let me know.... Kind regards, Howard Tanya’s decision: Extend the field test Dr. Phillips, Yes! I would gratefully agree to extend the field test! I'd jump at the chance to get rid of this darn MRSA. I already have a doctor's apt scheduled for day after tomorrow, Thursday @ 10.30 a.m. I will phone the clinic tomorrow to make sure they can accomadate the MRSA blood culture test. I will ask for a CFU count. I look forward to this opportunity and am agreeable to using the TABC for another 2-3 weeks. Thanks so much. So far, this has been a blessing and a miracle for me. Tanya MRSA Page 49
Consultation with Tanya’s health care provider, 1/20/2011. Notes by HP: I received a phone call from Dr. KC’s assistant and then spoke with Dr. KC. He wanted to discuss the kind of test that would be best. We talked about that, so that he could order a test that would be best, in his thinking, for getting a quantitative measure of MRSA bacteria in Tanya’s system. He considered both urine and blood tests, and decided on blood tests. He scheduled another appointment with Tanya two weeks from now, and will repeat the test at that time to evaluate progress toward our goal of driving the MRSA CFU count to zero. Other items of interest from Dr. KC during the phone call: n “Previously a skin culture was done. She had definitely had a MRSA infection © Phillips Company 2010 for some time.” n “I had treated her with clindamycin and over several months she would get a little better and then worse.” n “I see some real progress. She is very much better now.” Test plan to treat systemic MRSA using a topical mediction How do topical MRSA infections become systemic MRSA infections? MRSA infections may penetrate through the skin into the soft tissues beneath, and when this occurs, the infection can become very dangerous. If the bacteria stays in the lower layers of skin and connective tissue, it can cause an itchy red rash that spreads called cellulitis; if it seeps into the lower connective tissues called the fascia it can cause a “flesh eating” disease known as necrotizing fasciitis. The bacteria can also penetrate and colonize soft tissues and cause life-threatening organ damage, or they can escape on to into the bloodstream and cause widespread infection. This condition is called systemic MRSA. (Ref: http://www.healia.com/healthguide/guides/mrsa-and-other-staph- infections/what-are-the-symptoms-of-a-staph-infection ) MRSA Page 50
Symptoms of internal or systemic MRSA infection may include multiple skin rashes and other symptoms. Life-threatening internal MRSA infections can occur in the bones, joints, heart valves, lungs, and in the bloodstream. Infection of bone causes osteomyelitis, joint infections cause a painful arthritis, infection of the heart valves causes endocarditis, and lung infection tends to lead to pneumonia. When bacteria infect the blood it is called bacteremia and this may lead to septic shock, which is fatal in about half of cases. Tanya’s case was believed to be SYSTEMIC MRSA. The goal was to drive the MRSA out of her system. This means that the goal was to drive MRSA out of her bloodstream. The test plan adopted to do this was: Diagnosis before the use of TABC: “Previously a skin culture was done. She definitely has had a MRSA infection for some time,” according to her health care © Phillips Company 2010 provider. Phase 1: Treatment of her multi-location skin lesions -- Tanya’s lesions were treated with TABC for almost 2 weeks during which some TABC was introduced into her bloodstream and her lymphatic Ref: http://www.merckmanuals.com/home/sec18/ch201/ch201b.html fluids because some of her lesions were weeping at the time of TABC application to the lesions. Blood test #1: This test was carried out to determine how much MRSA was still present in her system. Phase 2: TABC topical treatment with the goal of driving bacteria out of her system. TABC is to be frequently applied to her skin in spots where blood vessels are near the surface of the skin, including the underarm side of the wrists, underarms (armpit area), the back of knees, the sides of the neck and the back of hands. The TABC will be “rubbed in” frequently, but especially right after a shower/bath, when the skin is red because of the dilated blood vessels. Blood test: This test will be carried out to determine how much BACTERIA can be found in her system, after approximately 2 weeks of TABC topical treatment. MRSA Page 51
Protocol details -- Systemic MRSA treatment began 1/21/2011 Tanya -- I recommend you begin the new procedure today, so we can have a FULL 2 WEEKS of treatment between the blood test today and the blood test planned for two weeks from now. TABC is to be frequently applied to your skin in spots where blood vessels are near the surface of the skin, including the underarm side of the wrists, underarms (armpit area), the back of knees, the sides of the neck and the back of hands. The TABC should be “rubbed in” frequently, but especially right after a shower/bath, when the skin is red because of the dilated blood vessels. How to do it: Each application of TABC requires ONLY A FEW DROPS for each location. For application in the underarm area, I would think about 4 or 5 drops of TABC would be enough. If you rub it in for about 20 seconds, it should all be gone. If any TABC remains after rubbing it in for 20 seconds, that means too much TABC was used. You can apply it frequently -- perhaps 4 times daily if that is convenient for you to do. © Phillips Company 2010 The goal is to "keep it on the skin," which can only be done with frequent re-application of the TABC. You can decide what is convenient for you to do, because there is no overdose issue with TABC. Look for this side effect: If we are really fortunate, we will get enough TABC in your bloodstream to kill all the MRSA bacteria. There is one thing to "watch for." About 15 or 20 minutes after you have applied the TABC, try to be aware of a mild taste in your mouth. The taste might remind you a bit of mild garlic, or perhaps a metallic taste. If you sense this it will be very mild and not easy to notice unless you are "looking for it." That probably will NOT be noticed, but if it is, please write down the timing of the taste, because that is very good information to have. We would LIKE for this sensation to occur with you, but I suspect it will not be noticed. The reason we WANT this sensation is that, if it should occur, it tells us that we really ARE getting good transfer of the tetracycline from the surface of the skin into the blood vessels. Kind regards, Howard Phillips Report from Tanya on the first day of the systemic MRSA treatment (1/21/2011) Dr. Phillips, I started the new protocol for the extended field study last night. I want to be sure I am applying the TABC correctly. I am continuing to apply the TABC to my MRSA sores. In MRSA Page 52
addition, I am putting 4 drops on; per location: behind both knees, in both armpits, on both inside wrists, and both sides of my neck, on each side of neck, near my windpipe (carodid artery location). I am applying the TABC at times when it is applied to the MRSA sores; at 8 a.m., noon, after each shower, (approximately 4 p.m.), after supper and half hour before bed. I have already 'tasted' that metallic taste in my mouth on the 2nd and 3rd days of application to my MRSA sores, when I was applying it most heavily. I tasted it (mild taste) this morning, also. I am a super taster, and although noticeable, it is not unpleasant, easy to accept, if the end result is successfully ridding MRSA from my blood. I am feeling so much better, that I have gotten back into life again. Before MRSA, I was a public-service writer. I have started writing again, and that is one of my favorite things to do! Thanks! Tanya © Phillips Company 2010 P.S. Medical history note: I have had hyperhydrosis since I was 5 yrs. old. I'm a sweaty person. I am also going through the menopause night sweats and hot flashes. Phillips Company note (1/21/2011) Tanya reported that she had “'tasted' a metallic taste on the 2nd and 3rd days of application to my MRSA sores, when I was applying it most heavily. I tasted it (mild taste) this morning, also.” 1. The taste is a very good indicator that the TABC is getting into the bloodstream. 2. Tanya’s report means that SOME TABC entered her bloodstream during the Phase-1 treatments, via the vascular fluid (weeping) that was present during Phase 1. Although this could have reduced the MRSA in her blood, we believe that was probably NOT sufficient to drive all the MRSA bacteria out of her system. Therefore, we recommended that she continue with the systemic MRSA treatment. No overdose issue is believed to be associated with the additional TABC treatments. MRSA Page 53
Dr. Phillips, All of the lesions and ulcers look better. They all have better color, and they have all improved. This one is is a photograph of my left ear. One can still see the little sore that came up 3 days ago, but it is healing nicely. Thanks, Tanya © Phillips Company 2010 Day 13 1/23/2011 Day 13 1/23/2011 MRSA Page 54
Dr. Phillips, here is photograph of the lesion on my left hip. The Day 13 previously-red color ring around this MRSA scar has 1/23/2011 faded and the skin has come back softer and supple. The little blisters are all gone and the skin has almost stopped flaking. The skin and underlying tissue around the scar tissue feels normal; not lealthery like scar tissue feels. Thanks, Tanya © Phillips Company 2010 Day 13 1/23/2011 MRSA Page 55
Dr. Phillips, Here is pic of base of spine with 2 MRSA Day 13 scars (from previous surgeries). One can see the 1/23/2011 lower scar/sore still has one little red spot. Yesterday that spot was itchy, so I put a drop of topical benedryl on it an hour before my shower, and it stopped itching. Then after my shower, I reapplied the TABC, and it hasn’t been itchy since. © Phillips Company 2010 Day 13 1/23/2011 MRSA Page 56
Note that the area of redness has faded away. The skin is growing back nice and pink, healthy looking. It is no longer tough or leathery; it is soft and normal feeling to the touch. It has stopped flaking. Please note also that some of the other little purple spots on left have faded as well. To the right of the larger MRSA scar, the skin still MRSA surgery was performed looks like it is healing from the blistering that was August 24, 2010 (this photo), near there 2 weeks ago. Considering how badly infected the base of the spine this area was, and considering that I coundn't lie flat on my back two weeks ago, this spot is healing back magnificently. Thanks, Tanya Day 13 © Phillips Company 2010 1/23/2011 (this pho- tograph) Tanya’s report dated 1/10/2011: “I had MRSA surgery which was performed August 24, 2010. This site reactivated (became inflamed/infected) just 2 weeks ago, before I began using TABC.” MRSA Page 57
Dr. Phillips, Here is an updated photograph of the location of the ulcer/ Day 13 lesion in front. This is the location where the largest ulcer was located. Although it 1/23/2011 was an open sore and weeping before I began using TABC, this ulcer has healed nicely. The blisters are gone, the skin has stopped flaking, and the dark angry red color has faded away. One can see where the blisters were; the skin is still in that location is still healing. The old scarline is designated by a white dashed line in the photograph below. Where the largest sore was (on the old surgery scarline), the skin is still purple colored; but it is softer to the touch, not stiff and hard skin like it was before I began using TABC. New skin is showing on the left end of the old scar, where the MRSA sore was worst. © Phillips Company 2010 Although the whole area has a kind of wrinkly appearance, it is still healing and new skin is coming in. It is soft, not rough; it is supple, not leathery. Thanks, I greatly appreciate how the healing is progressing. Tanya Day 13 1/23/2011 MRSA Page 58
Before TABC use Day 7 Day 13 Day 0 Day 7 Ear Ear Day 7 Day 13 Day 0 Chest Ear Chest Chest appeared healed by Day 13. No photo taken. © Phillips Company 2010 Day 7 Day13 Day 0 Hip Hip Hip Day 0 Day 7 Day13 Lower Lower Lower spine spine spine Day 7 Day 0 Front Front Day13 Front MRSA Page 59
Answers from Tanya about SYSTEMIC MRSA treatment (Day 14) a. Any occurance of tasting the “metallic/garlic” taste? Usually, Larry and I agree, we taste a garlic or metalic taste in our mouth when we apply TABC on an empty stomach, between meals. Larry says he tastes it especially after his hot shower in the afternoon before supper. I noticed it after applying TABC and exercising (brisk walking), before supper. Not too unpleasant, Not a deterent, just noticing it. If we eat and then apply TABC, we dont notice it. b. General feeling — feel good? © Phillips Company 2010 Yes we are both feeling happier, have a better attitude and feel like a weight has lifted from our shoulders. TABC has eased the MRSA burden on us—that dreaded feeling of “when will this come back” has faded away more every day. c. Good energy? Yes we both have better energy, Larry has gone out golfing twice in the past 2 weeks, and has enjoyed good satmina for his round, and gotten good scores. I used to go to bed between 8-9 p.m. Now I can stay up later, 10-10:30 p.m. I have been sleeping deeper and feel more rested when I awaken. d. Any appetite changes? Yes, I have been waking up hungry since about Day-4 (1.14.11) of the field test. That’s a good thing, because I had lost a lot of weight from the surgery, from having a cold and from using antibioitics over an extended period of time. I weighed 108 pounds, on Thursday (1.20.11) at the clinic using their scale. That’s a gain of 4 pounds since October 11, 2011. My apetite has improved, and I feel like baking again. I worked in a Menonite nursing home when I was young, (my dad’s family are Menonites) and they can cook! Now I am converting their recipes to gluten free (GF) organic recipes and I am really enjoying it! I made GF corn muffins on the 18th, and yesterday, the 23rd, I made a tasty GF apple-date-oat-spice cake that was delicious! MRSA Page 60
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