MEDICAL MATTERS Advancing Cancer Research

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MEDICAL MATTERS Advancing Cancer Research
MEDICAL
  L ANE COUNTY MEDICAL SOCIETY | APRIL 2023

                                              MATTERS

Advancing
Cancer
Research
Dr. Sharman’s work
with the US Oncology
Network puts Eugene
on the national map for
cancer research.

                                              REGISTER NOW
                                              LCMS 66th Annual
                                               Golf Tournament
                                                  June 17th
MEDICAL MATTERS Advancing Cancer Research
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MEDICAL MATTERS Advancing Cancer Research
THIS ISSUE

Contents
L ANE COUNT Y MEDIC AL SOCIET Y                             |    A PRIL 2023

         9
                                                           CANCER CONTROL MONTH

   GOLF
TOURNAMENT
Dr. Paul Chavin shares
                                      11
                                       WVCI
                                                                      12
                                                                      EUGENE
                                                                                                       14
                                                                                                      MEMBER
his vision and fundraising
                                                                      GASTRO                          PROFILE
                               Willamette Valley Cancer
goals for the upcoming         Institute and Research           Dr. Nathan Holman               Dr. Sharman shares how
66th Annual LCMS Golf          Center stresses the              emphasizes the increased        his interest in cellular
Tournament.                    connection between               risks for colon cancer and      biology led to his work as
                               preventive care and early        encourages screenings at        an oncologist.
                               detection with overall           45 instead of 50 years old.
                               treatment.

      19 20 23 25
          OSW                            PH                       ADVERTISER                          PWP
                                                                  SPOTLIGHT                        DONATIONS
Dr. Christine Kollmorgen       PeaceHealth talks about
states the importance of       new treatments for                                               Thank you to everyone
                                                                The Adrienne St. Clair
follow-up appointments         prostate cancer.                                                 who donated to the
                                                                Group shares about
to prevent and monitor                                                                          Physician Wellness
                                                                their knowledge and
potential side effects after                                                                    Program in 2022 and
                                                                connections when it comes
surgery.                                                                                        celebrated the 10-
                                                                to local real estate.
                                                                                                year anniversary of the
                                                                                                program.

                                                                                              MEDICA L M ATTERS | A PRIL 2023 3
MEDICAL MATTERS Advancing Cancer Research
MEDICAL             MATTERS
                                                                 Lane County Medical Society
                                                                    Executive Committee
                                                                           President
                                                                     Benjamin Vazquez, MD
                                                                          Past President
                                                                       Kevin Modeste, MD
                                                                     Vice President/Secretary
                                                                        Leslie Pelinka, MD
                                                                           Treasurer
                                                                       Bryan McVay, MD
                                                                      Executive Director
                                                                       Shondra Holliday
                                                                             Editor
                                                                      Kianna Cabuco, MBA

                                                                     Advertising Inquiries
                                                                     info@lcmedsociety.com
                                                                     Membership Inquiries
                                                                     Trina@lcmedsociety.com

                                                                 Lane County Medical Society
                                                                         PO BOX 7192
                                                                      Springfield, OR 97475
                                                                     Phone: 541-686-0995
                                                                       Fax: 541-687-1554
                                                                     info@lcmedsociety.com
                                                                     www.lcmedsociety.com

                                                                 LCMS Physician
                 i       ster                                    Wellness Program
             Reg   !
               Now
                                                                 Confidential Counseling
                                                                 Cascade Health or
                                                                 24-hour support line
                                         THE 66TH ANNUAL
                                                                 541-345-2800
                                     LCMS GOLF                   Stress Reduction Workshops
                                                                 Amy Trezona, RN
                                    TOURNAMENT                   541-912-0216
                                                                 Executive/Life Coaching
                                           JUNE 17, 2023         Shannon O’Leary
                                    EMERALD VALLEY GOLF COURSE   541-255-2669
                                                                 Karen McGovern
                                                                 920-903-0323
                                                                 Joseph Arpaia, MD
                                                                 541-912-1534
                                                                 Lifestyle Medicine
                                                                 Joseph Sage, MD
                                                                 541-600-2492

4 MEDICA L M ATTERS | A PRIL 2023
MEDICAL MATTERS Advancing Cancer Research
COMMITTEES UPDATE

LCMS Committees: Let’s Ideate
   Ideation is the process of forming ideas from conception to implementation. Ideation is expressed via graphical, written, or verbal
methods, and arises from past or present knowledge, influences, opinions, experiences, and personal convictions.
   The role of the LCMS Board is of utmost importance for the organization, but much of the work is done at the committee level.
For those interested in getting involved, but unsure if serving on the board is the right fit, committees offer an opportunity to make a
difference in the organization, in healthcare, or in the community through LCMS partnerships. Committees thrive when comprised of a
variety of individuals with a diversity of skills and expertise. Whether it’s financial prowess, affinity for wellness, passion for social causes,
event planning experience, or fundraising connections, there is something for everyone.
   The first committee meetings took place in March and each group spent time ideating about goals, establishing action items, and
identifying future projects or programs. Still in early stages, we’d welcome additional input or participation from LCMS members or the
community, but we’re off to a great start! The following information is not intended to be a complete list, but rather a glimpse into the
focus and direction of each committee.

   Community Health Committee                        Physician Wellness Program                       Membership & Events Committee
   Mission: Establish meaningful                     (PWP) Committee                                  Mission: Maintain a strong, robust
   connections and leverage the                      Mission: Evaluate program to                     organization and offer valuable
   collective power, influence, and                  ensure the highest quality and most              membership benefits.
   voice of LCMS to collaborate with                 diverse services offered to Lane                 Goals: Review benefits of
   community organizations with                      County physicians.                               membership and host (or co-host)
   similar goals. Maintain a focus on                Goals: Determine effective ways to               educational events on relevant
   education, all-inclusive outreach,                share program information, ensure                healthcare topics, social events
   and prevention.                                   availability of inclusive services,              aimed at creating connections, and
   Vision: Increase visibility of LCMS               confirm new provider vetting                     community collaborations to build
   in community events and activities.               process, and regularly monitor                   recognition of the Society.
   Goals: Work closely with other                    quality measures of services                     LCMS Events: See current events
   public health efforts by appointing               provided.                                        below. Other events are still in the
   liaisons and create a list of                     Ideas so far:                                    planning stage, so watch for updates
   connections and resources.                        • Review current providers for                   in upcoming communications.
   Ideas so far:                                       areas of expertise to determine                • May – Wellness Month (see insert
   • Increase awareness on the health                  potential gaps                                   for details)
      effects of alcohol                             • Work closely with PWP providers                • June 14th – “Nine & Wine” Social
   • Arrange YMCA “hard-hat” tour                      to establish program effectiveness               Event at Top Golf (all golfing is
      (Scheduled for April 20th)                     • Review PWP brochure to                           virtual for non-golfers!)
   • Provide opportunities for                         determine needed updates                       • June 17th – Charity Golf
      connections to social causes                   • Find “Champions” to serve as                     Tournament (benefitting Veterans
   • Engage community medical                          ambassadors for the program                      Legacy)
      leaders of tribes and immigrants               • Choose representatives to serve                • July 15th – Vineyard Event
   • Hold informational pop-up tents                   on the Foundation Board to best                • November 8th – Winter Social
      at the Saturday Market                           communicate the work of the                    • September 2024 – Biennial
   • Offer support/endorsements to                     PWP committee                                    Physician Wellness Program
      community projects with similar                • Solicit personal stories aimed at                Fundraising Gala
      missions and values                              normalizing conversations about
   • Survey LCMS membership to                         struggles and triumphs, including
      determine community health                       quotes from those utilizing
      priorities                                       services (can remain anonymous)

MISSING SOMETHING? Let us know! Or, better yet, consider joining a committee.
    It’s the perfect opportunity to help our leaders further the mission, connect with colleagues, and find strength and clarity in the work
of the organization. Committees typically meet every other month (2023 dates are listed on the LCMS website, www.lcmedsociety.com).
We’d welcome feedback and additional suggestions. It’s as simple as a phone call to 541-686-0995 or email to info@lcmedsociety.com.

                                                                                                              MEDICA L M ATTERS | A PRIL 2023 5
MEDICAL MATTERS Advancing Cancer Research
Your automotive future
has arrived in Eugene
E X P L O R E O U R A L L- E L E C T R I C E Q L I N E U P
MEDICAL MATTERS Advancing Cancer Research
NEWS

Chart Notes
“Right now,             Register Now! 66th                                                          UPCOMING
there are               Annual LCMS                                                                 EVENTS
over 4,000
medicines               Golf Tournament                                                             OMA Day at the
                                                                                                    Capitol is Monday,

being                   June 17th                                                                   April 17th. You must
                                                                                                    be an Oregon Medical
                                                                                                    Association member
developed               Grab some friends and
                        colleagues, and register
                                                           Graduate a few days before for
                                                           anyone that wants to join in on
                                                                                                    to attend. Learn more,

for cancer
                                                                                                    register, or join today
                        now for this year’s LCMS           the fun without spending a full          at theOMA.org.
                        Charity Golf Tournament
treatment.
                                                           day on the course.
                        benefitting Veterans Legacy                                                 Space is limited
                                                           So form a team for a day of              for a hard hat
What we are             at Emerald Valley golf
                        course on June 17th.
                                                           fun and prizes or come by the
                                                           social to connect with peers as
                                                                                                    tour of the new
                                                                                                    Eugene Family
seeing now,             Last year, we were able to raise   we head into summer.                     YMCA facility on
                        over $10,000 for Veterans
in terms                Legacy and Camp Alma. This
                                                           For more information about
                                                           Veterans Legacy, visit www.
                                                                                                    April 20th. Only 15
                                                                                                    spots are available. If
of cancer               year, the “Chair’s Choice” is
                        to once again support our
                                                           veteranslegacyoregon.
                                                           org or contact us at info@
                                                                                                    interested, email info@
                                                                                                    lcmedsociety.com to
research, is            veterans. Alongside the normal
                        golf tournament, LCMS will
                                                           lcmedsociety.com if you’re               add your name to
                                                                                                    the list.
                                                           interested in a tour of the
completely              be fundraising for Veterans
                        Legacy with the goal of
                                                           grounds.                                 LCMS would like
different               topping last year’s numbers.       All members are welcome
                                                           to both events, so sign up
                                                                                                    to thank our annual
                                                                                                    event sponsors
from what we            We’ll also be hosting a “Nine &
                        Wine” social at Top Golf at the
                                                           today!                                   and publication
                                                                                                    advertisers. As a
saw even five                                                                                       show of appreciation,
                                                                                                    we invite our
years ago...In                                                                                      past, present, and
                                                                                                    prospective advertisers
many cases,                                                                                         and sponsors to join

we may have                                                                                         us for a chance to
                                                                                                    mingle and connect
a therapy that                                                                                      on April 13th. This will
                                                                                                    also be an opportunity
is specific to                                                                                      to see what we have
                                                                                                    planned for the rest of
an individual’s                                                                                     2023 and how to get
                                                                                                    involved. For more
cancer.”                                                                                            information, email
                                                                                                    info@lcmedsociety.
– DR. JEFF SHARMAN                                                                                  com.
ON CANCER RESEARCH
& RESOURCES
FOR MORE, SEE PAGE 14

                                                                                             MEDICA L M ATTERS | A PRIL 2023 7
MEDICAL MATTERS Advancing Cancer Research
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8 MEDICA L M ATTERS | A PRIL 2023
MEDICAL MATTERS Advancing Cancer Research
COMMUNITY

66th Annual
LCMS Golf Tournament
   As we get ready for this year’s golf          forever, and I knew he ran Veterans             you hit the ball 100 yards and you have a
tournament, LCMS is also planning a pre-         Legacy and Camp Alma. I also knew it            player on your team that hits it 200, you
tournament social for golfers, non-golfers,      had little formal support. Being an ex-         play from the 200 yard spot. It also means
new members, and those simply wishing to         Navy man, I am very partial to veterans,        when you have the best ball on the green
connect. We’ll be in the Top Golf suite at       so I felt this was ideal. The second idea       you have four chances to make the putt.
the Graduate a few days before for a “Nine       was to invite more women and younger            This allows players at all levels to join in
& Wine” get together. (Get it? “Nine” like       docs to create another opportunity for          on the fun. The club pro at Emerald Valley
9 holes, a half round of golf! We’re quite       socializing and relay that this event is open   will help with handicaps and scoring,
clever.) This is also an opportunity to learn    to ALL members.                                 and the funds raised will go again to
more about Veterans Legacy and socialize                                                         Veterans Legacy with the goal to surpass

                                                    “As doctors, it is
with peers as we move into summer. Keep an                                                       last year’s donations.
eye out for the chance to RSVP!                                                                     At Camp Alma, Vets are given the

And now, a message from the 66th                   second nature to                              chance to put their lives back together and
                                                                                                 readjust to civilian life, which is not always
Annual Golf Tournament chairman,
Dr. Paul Chavin:                                     help others. It’s                           an easy or smooth transition. Considering
                                                                                                 our freedom and wonderful lives are
    Some might call it serendipity, but I           just who we are.                             made possible by the soldiers, sailors, and

                                                   So uncover those
would be the first to say I became chairman                                                      marines that protect us, we should do our
of the golf committee mostly by accident.                                                        best to help them when they come home.
I had one of those memorable days where
golfers – if lucky, play better than their            golf clubs and                                If you have a chance to Camp Alma,
                                                                                                 take it. See for yourself the difference
handicap would indicate. Putts seemed
to magically find their way into the hole.
                                                     pull together a                             Veterans Legacy is making and how much
                                                                                                 there is still left to do. As doctors, it is
So after that very lucky day on the golf
course, I won a bunch of money and the
                                                  team. Let’s make it                            second nature to help others. It’s just who
                                                                                                 we are. So uncover those golf clubs and
honor to chair the golf tournament the                  happen.”                                 pull together a team. Let’s make it happen.
following year. Then, Covid hit!
    The year when Covid was in full bloom,                                                       Birdies forever,
no events were happening including the              Shondra Holliday and the staff did                 Paul Chavin
golf tournament. The following year, it was      all the heavy lifting, including securing
up to me to restart planning of the 65th         sponsors, food, and prizes for the event.
annual tournament. I pulled together a           They were integral in making the golf
committee of eight guys and one gal.             tournament a successful event.
Among the suggestions was to run it like            At the end of the day, we had happy
it has always been. I felt I was just not into   players and were able to raise $10,000
running a “good old boys” tournament             dollars for Veterans Legacy.
again, and the suggestion had surfaced for          This year, we are hoping to make it
a possible fundraiser. I was thrilled with       even better. We will be back at Emerald
the idea and even had an idea in mind of         Valley Golf Course in Creswell on June
who we might support.                            17th. The format will be a team event
    Dr. John Lebow and I have been friends       with the best ball format. That means if

                                                                                                           MEDICA L M ATTERS | A PRIL 2023 9
MEDICAL MATTERS Advancing Cancer Research
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 10 MEDICA L M ATTERS | A PRIL 2023
CANCER CONTROL

Taking Preventive Measures
BY WILLAMETTE VALLEY CANCER                        available preventive options (Samimi and           the best course of treatment.5 Treatments
INSTITUTE AND RESEARCH CENTER                      others, 2019).3                                    may include active surveillance, surgery,
                                                                                                      chemotherapy,          targeted      therapy,
   April is National Cancer Control                Early Detection                                    hormone therapy, immunotherapy, stem
Month. Originally instituted by President             Skin cancer, cervical cancer, and               cell or bone marrow transplant, and/or
Franklin D. Roosevelt in 1943, each                colorectal cancer are the most preventable         radiation therapy. Except for transplants,
year the sitting president has made an             types of cancer. In addition to education          which require extended hospital stays,
annual proclamation and renewed the                on prevention strategies, such as limiting         all these therapies are available through
Nation’s commitment to reduce the                  UV, vaccinations, and healthy nutrition,           Willamette Valley Cancer Institute and
incidence, morbidity, and mortality of             regular screening should be emphasized             Research Center or our Oregon Cancer
cancer and to improve the quality of life          to find lesions or abnormal cells before           Alliance partners in Lane County.
of cancer patients.                                they become malignant.                                 In fact, radiation therapy at WVCI has
   We’ve come a long way since 1943,                  “…With proper vaccination and                   recently been enhanced with the addition
cancer incidence and death rates have              screening for HPV, in theory, no woman             of a Varian TrueBeam linear accelerator.
been on a slow, steady decline in Oregon           should lose her life to cervical cancer in         The TrueBeam joins WVCI’s Halcyon in
and across the country for decades. But            the US.” – Dr. Charles K. Anderson, MD             the suite of radiotherapy tools available to
according to the Oregon Health Authority,             That leaves 50% (or more) of cancers            treat cancer.
malignant neoplasms continue to be the             that are not preventable. Non-modifiable               “We’re well positioned to give the
leading cause of death in Lane County              risk factors include age, gender, race/            best types of [radiotherapy] treatments
(and all of Oregon), followed closely by           ethnicity, and family history/genetics.            currently available in North America to
heart disease, then COVID-19, which was a          Reducing morbidity and mortality for               our patients.” – Adil Akhtar, Chief Medical
distant third. This year there are expected        these cancer cases begins with education           Physicist, WVCI
to be 26,030 new cases of cancer in Oregon         about risk factors, common symptoms,                   The      TrueBeam       has    RapidArc
from among our patients, neighbors,                and the appropriate cancer screening               technology that delivers 3-D sculpted
colleagues, friends, and family members.1          recommendations.                                   beams, which match the shape of tumors
   Cancer Control Month is a good                     Studies show that some screening tests          from every angle. Its sophisticated
time for each of us, as part of a larger           that detect abnormalities before they are          motion management targets tumors with
healthcare community, to review our part           clinically apparent improve mortality              accuracy measured in sub-millimeters.
in the prevention, early detection, and            rates, while others do not.4 According             This precision makes it especially useful
treatment of cancer.                               to the NCI, expert groups generally                for treating all types of cancer, including
                                                   recommend regular screening for the                some of the most common such as
Prevention
                                                   following cancer types: breast, cervical,          prostate, breast, and rectal cancer.6
   According to the World Health                   colorectal, and lung (high risk only).                 The speed of imaging, higher intensity
Organization, 30-50% of all cancer                                                                    doses, and extreme accuracy ensures
cases are linked to modifiable risk                Diagnosis & Treatment                              patients get exactly what they need, where
factors. Prevention is still the most cost-           When cancer is detected by screening            they need it, with less time on the table and
effective, long-term strategy for the              or suspected due to presentation of                fewer treatments. What was unimaginable
control of cancer. 2                               signs/symptoms,      diagnostic      testing       15-20 years ago, is now becoming standard
   Primary care physicians have a                  and interpretation by a pathologist and            care for improving clinical outcomes and
critical role in delivering preventive             a radiologist is critical for diagnosis,           quality of life for patients with cancer. u
healthcare services. Studies have found            staging, and to help inform clinical
that the most important factor that                decisions by oncologists. Based on this            For more information about cancer
predicts cancer prevention uptake is               information and working in conjunction             treatments and related topics, visit
physician recommendation, which is                 with surgeons, gastroenterologists, and            www.oregoncancer.com.
dependent on physician familiarity with            pulmonologists, a joint decision is made on
1. “Cancer Facts & Statistics” American Cancer Society, Web. https://cancerstatisticscenter.cancer.org/#!/state/Oregon, accessed 3/9/2023
2. “Preventing Cancer” World Health Organization, Web. https://www.who.int/activities/preventing-cancer, accessed 3/9/2023
3. “Cancer Prevention in Primary Care: Perception of Importance…https://www.amjmed.com/article/S0002-9343(19)31095-2/fulltext, accessed 3/9/2023
4. “Cancer Screening Overview (PDQ) – Health Professional Version”, National Cancer Institute. Web. https://www.cancer.gov/about-cancer/screening/hp-
screening-overview-pdq, accessed 3/10/2023
5. “What Cancer Screening Tests Check for Cancer?”, National Cancer Institute. Web. https://www.cancer.gov/about-cancer/screening/screening-
tests#recommended-cancer-screening-tests, accessed 3/10/2023
6. “TrueBeam”, Varian, Web. https://www.varian.com/products/radiotherapy/treatment-delivery/truebeam, accessed 3/10/2023
                                                                                                                MEDICA L M ATTERS | A PRIL 2023 11
CANCER CONTROL

45 is the New 50!
BY NATHAN HOLMAN, MD
EUGENE GASTROENTEROLOGY CONS.
                                                percent decline in colonoscopy screening.
                                                This, in turn, resulted in a 32 percent              “Colon cancer
   Cancer kills around 600,000 people
                                                decline in new colon cancer diagnoses.
                                                Throughout 2020, the overall number
                                                                                                screening has been
annually in the United States. Of all
malignancies, colon cancer is the third
                                                of colonoscopies performed declined            shown to reduce the
                                                                                                 risk of developing
                                                by around 25 percent in comparison to
most common cancer diagnosed among              2019. While this number did improve
both men and women. The American
Cancer Society currently estimates that
                                                in 2021, overall colon cancer screening
                                                was still roughly 3.4 percent down from         colon cancer by up
there will be roughly 153,000 new cases
of colorectal cancer diagnosed in 2023.
                                                the years leading up to the pandemic.
                                                Epidemiologic models predict that by the
                                                                                                   to 90 percent in
Colon cancer prevention has faced new
challenges in recent years, with the
                                                year 2040 there will be an extra 4000 to
                                                7000 colorectal cancer deaths related to
                                                                                                     some studies.”
COVID-19 pandemic having brought                delays in screening during the pandemic.      is owed to the fact that a colonoscopy
about a substantial decline in routine              Another challenge facing colon cancer     has the ability to view the entire colon
screenings. There has also been increasing      prevention as of late has been the alarming   while also allowing for detection and
evidence that colon cancer is on the rise       increase in colon cancer incidence among      removal of precancerous polyps. The
among the younger population, leading to        younger people. Recent studies show an        American Society for Gastrointestinal
updated colon cancer screening guidelines       uptick in colon cancer incidence of 2%        Endoscopy (ASGE) has stated that it
in 2021. March was Colon Cancer                 per year among patients under 50. The         is also the only test that is suitable for
Awareness Month, and it is important to         American Cancer Society has reported          individuals who have risk factors such as
discuss these recent challenges as well         that people born in 1990 have double the      family history of colon cancer. There are
as changes surrounding colon cancer             risk of colon cancer and quadruple the risk   also stool based testing options, though
prevention. It is also essential to highlight   of rectal cancer compared to those born in    these require more frequent checks than
the excellent methods available for             1950. Research is still ongoing as to why     a high-quality colonoscopy. A FIT test
reducing one’s chance of succumbing to a        this may be, though there is some evidence    (fecal immunochemical test) detects
largely preventable disease.                    that suggests environmental factors           microscopic amounts of blood in the stool
   Colon cancer screening has been shown        such as obesity, poor diet, and sedentary     and should be undertaken annually. The
to reduce the risk of developing colon          behavior play a role. In response to this     Cologuard test is another stool-based test,
cancer by up to 90 percent in some studies.     data, multiple societies, including the       which detects both microscopic blood as
In spite of a clear benefit, the CDC reports    American Cancer Society as well as US         well as DNA cancer markers, and it must
that only around 70 percent of eligible         Preventive Services Task Force, are now       be done every three years. While both can
adults are up to date with their screening.     recommending colon cancer screening           offer some protection as they can detect
At the start of the COVID-19 pandemic,          start at 45 instead of 50. This is quite a    anywhere from 79-92 percent of cancers,
the Centers for Medicare and Medicaid           monumental change and bears repeating:        they are only able to detect a fraction of
Services recommended all non-urgent             45 IS THE NEW 50. Help us spread              precancerous polyps when compared
procedures be delayed, resulting in a 90        the word!                                     with colonoscopy.
                                                    With these challenges in mind, it is          As the US Preventive Service Task
“Recent studies                                 clear that colon cancer screening will        Force has noted, “the best screening test

show an uptick                                  require a stronger emphasis moving
                                                forward. There are a variety of screening
                                                                                              is the one that gets done.” This is certainly
                                                                                              true, as any test is better than no test,

in colon cancer                                 tests that can be done, though current data
                                                suggests that a high-quality colonoscopy
                                                                                              though it is worth keeping in mind that
                                                                                              the colonoscopy is currently our best tool
incidence of 2% per                             is the best available method. This test is
                                                associated with the highest number of
                                                                                              to detect and prevent colon cancer. Talk to
                                                                                              your patients about getting screened, and
year among patients                             colon cancer cases avoided, assuming          help save lives by spreading the news that

under 50.”
                                                one gets testing at regular 10-year           when it comes to colon cancer screening,
                                                intervals. The high quality of this exam      45 IS THE NEW 50! #45isthenew50 u

12 MEDICA L M ATTERS | A PRIL 2023
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                                                    MEDICA L M ATTERS | A PRIL 2023 13
MEMBER PROFILE

   Advancing
    Cancer
   Research
         Dr. Sharman’s early interest in cellular
          biology has led to the development of
            multiple cancer treatment drugs.

I
                                  BY ALAN SYLVESTRE
                         FOR LANE COUNTY MEDICAL SOCIETY

              n recent years, medical discovery continues to achieve new milestones.
              Physicians have access to new information parallel to advancing technology
              and innovation.
                 For Dr. Jeff Sharman, Director of Research at Willamette Valley Cancer
              Institute and Research Center, and Medical Director of Hematology
              Research for the US Oncology Network, he has seen a drastic change in the
              biologic understanding of cancer and an explosion of novel technologies to
              treat the disease.
                 “For many years, we had limited knowledge of what caused cancer to
              grow,” Sharman says.
   “Furthermore, the tools we had to treat it were very rudimentary and non-specific.”
   Now, he says the dynamics of an oncologist’s ability to treat cancer has shifted with the
growing advances in medicine.
   “Right now, there are over 4,000 medicines being developed for cancer treatment,”
Sharman says. “What we are seeing now, in terms of cancer research, is completely different
from what we saw even five years ago,” he says. “Take non-small cell lung cancer as an
example. We used to divide it into three different diseases: adenocarcinoma, squamous cell
carcinoma, and large cell carcinoma. Now, we recognize that there may be 10-20 important
molecular drivers that can vary from one cancer to the next. We can identify each of those

                                                         MEDICA L M ATTERS | A PRIL 2023 15
MEMBER PROFILE

                                                                                             he discovered his specialty.
“Knowing, appreciating, and                                                                      “It was within my first year of medical

understanding what happens at the
                                                                                             school that I knew I wanted to be an
                                                                                             oncologist,” Sharman says. “I really fell in

cellular level is what oncologists manage                                                    love with immunology as a subject matter,
                                                                                             such as lymphomas and leukemias are
on a daily basis.”                                                                           cancers of the immune system. At that
                                                                                             point, it became clear that I wanted to
                                                                                             specialize in blood cancers.”
drivers at the DNA and protein level. In       be present and be there for them.”
                                                                                                 Over the span of his career, Sharman
many cases, we may have a therapy that is         Especially with a terminal diagnosis,
                                                                                             has helped develop multiple cancer
specific to an individual’s cancer.”           he believes the most important thing
                                                                                             drugs, and his research has provided the
    Having the knowledge of how a disease      someone can do is provide time.
                                                                                             Willamette Valley Cancer Institute access
works at a molecular level has allowed            “Time is one of the things you can’t get
                                                                                             to new areas of cancer studies that include
oncologists to cure forms of cancer that       back later,” Sharman says. “So be kind, be
                                                                                             immunotherapy, targeted therapy, and
once weren’t possible.                         supportive, and just be there.”
                                                                                             personalized medicine.
    “Five years ago, I would not have said        He understands the challenging task of
                                                                                                 His current work as the medical
you could cure anyone with metastatic          being present while dealing with potential
                                                                                             director of hematology research for The
melanoma, but now we can,” Sharman             emotional and physical hardships.
                                                                                             US Oncology Network has helped put
says. “Now, approximately 10 to 15 percent        “Nobody wants to face an illness,”
                                                                                             Eugene on the national map in terms of
of patients with a metastatic disease can be   Sharman says. “But if we can use it to
                                                                                             cancer research.
cured. And we hope to move that number         pause and evaluate the relationships we
                                                                                                 “We have been able to lead multiple
higher as tools emerge that are going to let   have, it can actually be an opportunity.
                                                                                             global phase three trials from here in
us do that.”                                   That’s not to dismiss, in any way, the
                                                                                             Eugene,” Sharman says.
                                               hardships associated with cancer.”
Be Present                                                                                       During his time in Eugene, he has
                                               Science & Cells                               published over 90 papers including three
    Although medical breakthroughs are
                                                                                             in the New England Journal of Medicine
arriving at rapid rates, Sharman says that         Science was always a field that excited
                                                                                             and a first author manuscript published
the majority of patients diagnosed with        Sharman.
                                                                                             in The Lancet.
metastatic cancer will not be cured.               “My undergraduate studies were
                                                                                                 Currently, the US Oncology Network is
    “It can be tricky in this new era to       in biochemistry and cellular biology,”
                                                                                             merging with the Sarah Cannon Research
carefully navigate patient expectations        Sharman says. “I was always fascinated
                                                                                             Institute to become the largest cancer
where there is so much optimism, yet           by the chemistry of how things worked in
                                                                                             research program in the world.
the journey remains frightening and            living systems. And cellular biology is the
                                                                                                 “One in five US patients treated for
uncertain for the patient. It is so            study of what turns cells on and off.”
                                                                                             cancer will receive their care through the
important to be present for the patients           Originally having no interest in
                                                                                             combined organization,” Sharman says,
where they are emotionally,” Sharman           medical school, Sharman says his studies
                                                                                             “which gives us an unprecedented level of
says. “One strategy might not work             in cellular biology created the foundation
                                                                                             access to research.”
on every patient since every cancer            for his work as an oncologist.
                                                                                                 In his role leading the blood cancer
diagnosis is unique. It’s important to             “Knowing,        appreciating,     and
                                                                                             research program, Sharman will help
keep a patient informed of their status        understanding what happens at the
                                                                                             identify promising new therapies and
as it evolves.”                                cellular level is what oncologists manage
                                                                                             bring them to patients in Eugene.
    And what happens when that status          on a daily basis,” he says. “I don’t take
                                                                                                 Sharman has focused a lot of his
matures into a terminal diagnosis?             out livers, or transplant hearts, or fix
                                                                                             research on medications that impact
    Sharman says over his years as an          bones because that’s not my skill set.
                                                                                             B-cell receptor signaling.
oncologist, he has one piece of advice he      But when it comes to understanding
                                                                                                 “B-cells give rise to the majority of
gives to family members and friends.           molecular switches and the interactions
                                                                                             lymphomas and leukemias,” he says. “As a
    “I think it’s important to be present      of the immune system, to me, that
                                                                                             fellow, I had the idea that interfering with
and be there with your loved one,”             is really interesting.”
                                                                                             that signaling might prove to be of benefit
Sharman says. “Oftentimes, people want             After his undergraduate graduation, he
                                                                                             for patients with those cancers.”
to try and solve problems that might not       says it became apparent to him to pursue
                                                                                                 Fast forward 15 years, and the
exist. Ultimately, it’s important to simply    medical school, and it wasn’t long before

16 MEDICA L M ATTERS | A PRIL 2023
MEMBER PROFILE

therapies that emerged from that idea       it’s because of the culture, or the type of     know of them.”
have revolutionized the management of       physicians who want to work in Eugene,              Staying connected to other specialists
chronic lymphocytic leukemia and several    there’s a level of medical sophistication       is a perk of the region’s medical community
types of lymphoma.                          that exceeds similar communities in             that he enjoys. The sense of community
    “B-cell receptor signaling inhibitors   terms of our average demographic.”              and collaboration across specialties and
like ibrutinib and acalabrutinib have           Having practiced in Lane County since       organizations provides a network that
transformed the management of this          2005, Sharman says there’s no reason he         helps him provide the best care he can
disease. When I started at WVCI, all        would ever leave because patients don’t         for his patients.
we had was chemotherapy for these           have to travel far to receive great care.           “I can’t tell you how many times I’ve
patients. Now we don’t use chemotherapy         “The skills of the subspecialists we can    been in a room with a patient, and I
at all,” Sharman says. “Targeted            leverage is surprising and refreshing,” he      know they’ve seen another doctor and
agents     have    completely    replaced   says. “I have a great deal of trust in all of   there’s something important about that
traditional treatments.”                    my colleagues to provide high-quality care      visit that I need to know,” Sharman says.
    The story of these molecules recently   for our patients.”                              “Sometimes, I can just call them when I’m
was published in a novel entitled For           Sharman attributes some of the              in the exam room because I have them
Blood and Money by Nathan Vardi.            strength of the medical community to            on speed dial, and we can talk out their
Sharman is included as a character          organizations like LCMS that support            oncological situation right there.”
in the novel.                               local physicians.                                   Lane County provides a balanced
                                                “LCMS represents a communication            combination         of     knowledge   and
A Strong Medical Community                  vehicle across specialties,” Sharman says.      accessibility.
  “The medical community in Lane            “It helps me stay connected to other                “It’s the perfect size of a medical
County is unusually robust for a            physicians in the area. It’s a small enough     community because it’s not too big,
community of this size,” Sharman says.      community where I might not know every          and it’s not too small,” Sharman says.
“And what I mean by that, is whether        doctor on an individual basis, but we           “It’s just right.” u

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                                                                                                                       EUGENE MAGAZINE | FA L L 2021   31
CANCER CONTROL

Damage Control:
Lymphedema Prevention
After Breast Cancer Treatment
BY CHRISTINE KOLLMORGEN, MD                    collateral damage.                             planning, and sentinel lymph node biopsy.
OREGON SURGICAL WELLNESS                           Because of stories like Alison’s, it is    Finally, the importance of robust follow-
                                               important that our medical community           up cannot be stressed enough. Meticulous
   Prior to her breast cancer diagnosis in     stays up-to-date by offering patients state-   post treatment history taking, and physical
2017, Alison (name has been changed to         of-the-art and innovative solutions. Some      exams are highly recommended for early
protect her identity) was considered by        life-saving treatments will occasionally       detection. Working closely with regional
her friends and family to be ‘exceptionally    cause collateral damage. Lymphedema,           physical therapists and integrative
strong and healthy for her age’. She           a well-known side effect of surgery and        providers who specialize in lymphedema
practiced yoga, walked daily, and was a        oncologic treatments to the breast and         treatment and prevention can also make a
full-time hairdresser in addition to co-       under arm, can be a source of discomfort       big difference.
owning a small sustainable farm with her       and in some cases significant disability.         Taking these strategies to another level,
husband. She even ran a farmers’ market        The common symptoms include; swelling          the teams at Oregon Surgical Wellness
stand on seasonal weekends. Her plan was       of part or all of the arm, back, and chest     and Pacific Integrative Oncology are
to work “forever,” as she loved being active   wall, a feeling of heaviness or tightness,     working collaboratively to double down
and engaged in her community. She chose        restricted range of motion, recurring          on lymphedema prevention. With a grant
to have a bilateral mastectomy without         infections or hardening and thickening         from the OHSU Knight Cancer Institute
reconstruction – so she could get back to                                                     Community Partnership Program, “The

                                                  “No one stressed
her regular life quickly. Three sentinel                                                      Feasibility of a Remote Lymphedema
lymph nodes were taken on the side with                                                       Prevention Program for Newly Diagnosed
the cancer, and she went on to receive
chemotherapy and radiation treatments.             that I should be                           Breast Cancer Patients Undergoing
                                                                                              Surgery” is a pilot program that aims to
Routine follow up appointments
with her oncologists, surgeon, and
                                                  on the lookout for                          find out if a “change in knowledge” about

                                                    lymphedema.”
                                                                                              lymphedema prevention will improve
PCP were scheduled.                                                                           patient satisfaction and speed access to
   Looking back, she says, “NO ONE                                                            lymphedema care. The goal is to recruit
stressed that I should be on the lookout       of the skin.                                   50 patients who have had or will be having
for lymphedema.”                                   While lymphedema is often diagnosed        axillary lymph node surgery for this
   It was during these follow up visits        by a clinician, proactive care is better       important study. If you or your patients
that she mentioned pain and heaviness          than reactive care if we know our patients     are interested in this prevention course
in her right arm. These symptoms               are at risk. Taking steps to decrease          scan the QR code below. With collective
progressed over the next two years, and        the incidence of this condition are very       commitment to lymphedema prevention,
her lymphedema, formally diagnosed             important if we want patients to achieve       the hope is that stories like Alison’s
in 2019, became so severe that she was         optimal quality of life. While there are no    will be rare, and that collateral damage
deemed ‘permanently disabled’. She had         guarantees we can prevent lymphedema           from cancer treatments will be more
to quit her job and was no longer able         altogether, there are dramatic benefits to     manag eable
to engage in the farm stand work that          early detection as this chronic condition      and         less
brought such purpose to her life. To this      is more manageable when detected early.        severe. u
day, despite active compression, self-         Strategies to improve post treatment
treatments at home, and physical therapy,      quality of life include: ample patient
her symptoms remain a constant battle          education, the use modern scientifically
to control. While she is grateful to have      proven surgical techniques like axillary       Scan the QR
survived her cancer, she is frustrated and     reverse mapping (ARM) which reduces            code to access
disappointed to be left with debilitating      the risk by up to 15%, careful surgical        the course.

                                                                                                      MEDICA L M ATTERS | A PRIL 2023 19
CANCER CONTROL

New Cancer Treatments
in the Region
BY SHERRI BURI McDONALD                       Portland to offer it.”                         nuclear technologist Toni Bamford. It
COMMUNICATIONS SPECIALIST                        Referrals for Pluvicto™ treatment           claimed her mother’s life 20 years ago.
PEACEHEALTH
                                              generally come from oncologists or                 “When you see someone go through
                                              urologists. A PET scan confirms the            this, you want to do everything you can to
    Prostate cancer is the second most
                                              disease, then six treatments are given         try to help others who are going through
common cancer among men in the United
                                              six weeks apart. Pluvicto™ is delivered        it,” Bamford says.
States, just behind skin cancer.
                                              through an IV and each infusion                    When Bamford heard that Lutathera®
    This year, 288,000 new cases will be
                                              generally takes less than 10 minutes.          was available, she and fellow technologist
diagnosed and nearly 35,000 people will
                                              Each appointment is longer than that,          Erica Bennett made it their mission to
die from prostate cancer, the American
                                              however, to allow time for questions and       bring it to their community. It took them
Cancer Society estimates. So when new
                                              for monitoring after the infusion.             and their fellow nuclear technologists
treatments become available, they are
                                                                                             about a year.
sure to generate interest.
                                                 “When you see
                                                                                                 They researched state and federal
    That is the case with Pluvicto™, a new
                                                                                             radiation safety requirements. They
treatment for a specific type of prostate
cancer. Pluvicto™ binds a therapeutic         someone go through                             followed the process to amend the
                                                                                             hospital’s radiation license. They worked
                                               [a cancer diagnosis
radioactive particle to a carrier compound.
                                                                                             with the manufacturer to set up a
It targets a protein found on most prostate
                                                                                             treatment area and learned how to safely
cancer cells, delivering a high dose of
radiation to diseased cells and steering         and treatment],                             dispose of the waste. They also figured
                                                                                             out how to get referrals and bill for
clear of healthy ones.
    In early July, the nuclear medicine
                                                  you want to do                             the treatment.

team at PeaceHealth Sacred Heart
Medical Center at RiverBend in Springfield
                                               everything you can                                By the time the FDA gave Pluvicto™
                                                                                             the green light, everything was already

treated their first patient with Pluvicto™,   to try to help others                          in place.
                                                                                                 “The day it was approved, we were
soon after it received FDA approval.
Today, the team is treating 20 patients,          who are going                              ready,” Bamford says.
                                                                                                 “Theranostics in nuclear medicine –
some from as far away as California and
eastern Oregon.
                                                   through it.”                              using one radioactive drug to diagnose and
                                                                                             a second one to treat – holds great promise
    The team’s ability to treat more
                                                                                             in cancer care,” Dohrman says. “Our team
patients is only limited by the supply
                                                 PeaceHealth Sacred Heart Medical            looks forward to the development and
of Pluvicto™.
                                              Center at RiverBend was able to quickly        approval of additional treatments for
    “Pluvicto™ has the potential to
                                              start offering Pluvicto™ because the           other types of cancer. We understand that
extend the lives of people who have tried
                                              nuclear medicine team had already laid         therapies for brain cancer and kidney
other treatments for this specific type of
                                              the groundwork to offer Lutathera®,            cancer are in the pipeline.” u
prostate cancer,” says Dr. John Dohrman,
                                              a different treatment by the same
medical director of the 10-member
                                              manufacturer for a certain type of             For more information or questions about
nuclear medicine team. “We’re proud to
                                              neuroendocrine cancer.                         the treatments at PeaceHealth Sacred
be among the first nonuniversity hospitals
                                                 Neuroendocrine cancer affects far           Heart Medical Center at RiverBend, call
in the country to offer this therapy and to
                                              fewer people than prostate cancer, but it      541-222-2729.
be the only Oregon hospital outside of
                                              played a big role in the life of PeaceHealth

20 MEDICA L M ATTERS | A PRIL 2023
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24 MEDICA L M ATTERS | A PRIL 2023
2022
PHYSICIAN WELLNESS
PROGRAM DONATIONS
$5000 & more                       Up to $500                        Up to $100
William Flanary                                                      Nicholas & Rachael Wolfgang
                                   Bob Stephenson
                                   Karthik Mahadevan                 Amy King
Up to $2500                        Margaret Pattison                 Jodi Paoli
                                   Alice & Daniel Horrell            Leita Dzubay
Jim & Sylvia Emory
                                   Charlotte Ransom                  Paul Rockey
Joseph Arpaia
                                   Donald Garbett                    Amit Kainth
Brooke & Christopher Kyle
                                   Peter Karth                       Claire Murphy
                                   Thomas & Amy Trezona              Colette Khan
Up to $2000                        Denis McCarthy                    Dan Bowers
Andrew McIvor                      Lauren Herbert                    Naomi Light
Brittany & Marius Pakalniskis      Duc Vo                            Mark Lyon
Richard & Lori Beyerlein           Charles Stanton & Julie Gemmell   Thomas Seddon
Kimberly Ruscher & Kevin Modeste   Richard Padgett                   Randy Lewis
Audrey Garrett & Craig Seidman     Jessica Versage                   William Miller
                                   Lorne Bigley & Beth Moore         Thomas Harburg
                                                                     Bryan & Pamela Andresen
Up to $1000                        Lee & Mary Jean Michels
                                   Eric Spencer
Kathleen Cordes                    Paul Chavin
Garret & Angela Zallen             Marc & Tina Schnapper
Gary Josephsen
Joseph Sage
                                   Diane Baird
                                   Jocelyn Park
                                                                     THANK YOU!
Benjamin Vazquez                   Troy Richey                       2022 celebrated the 10-year
Kathleen Yang                      James McGovern                    anniversary of the LCMS
Healther Campion                                                     Physician Wellness Program and
Mark Mildren                       Up to $250                        our first PWP Fundraising Gala
                                                                     that raised over $50,000 to help
Lucas & Ashlene Korcek
Carmina Angeles                    Leslie Pelinka                    sustain the program. We're proud
Jonathan Sherman                   Shannon O'Leary                   to share that on top of
Katie Swank & Geoffrey Gil         Judith Sabah                      counseling services, the PWP also
Shelli Flynn                       Joy Pendowski                     offers executive and lifestyle
Sandra Rood                        Tamara Barstow                    coaching, stress reduction
Allan Hunter                       Laura Sanderson                   workshops, and more with
Luci Kovacevik                     Rechelle Asirot                   various providers allowing
William MacMaster                  John Lundeen                      members to find a good match.
Mark Hereema                       Amandajo Sanders                  We look forward to the
Glenn Buchanan                     John Lebow                        continued expansion of PWP
John & Leslie Polansky             Misty Carlson                     services offered in 2023 and
                                   Michelle Taube                     partnerships with our physician
                                   Fay Sunada                        community to keep this program
                                   Frances Munkenbeck                growing. For more information
                  SCAN TO          John Perkins                      about the PWP, visit
                  DONATE           Jenna Godfrey                     www.lcmedsociety.com/pwp.
NEWS

Announcements
New Members                      April 17th. Join the Oregon
                                 Medical Association in Salem
                                                                     Get ready for the LCMS
                                                                     Wellness Month challenges
                                                                                                        Notes
Jaime Fair, MD                   to connect with political leaders   in May. It’ll kick off with an     2023 Directories are here!
Internal Medicine                about upcoming legislation          Outdoor Group hike May             All preorders have been
McKenzie-Willamette MC           that could impact healthcare.       6th with LCMS president,           delivered. If your office would
1460 G Street                    Attendees must be OMA               Dr. Benjamin Vazquez, and          like to order one, contact info@
Springfield 97477                members. Learn more, register,      continue throughout the            lcmedsociety.com.
P: 541-726-4400                  or join today at theOMA.org.        month with a few community
F: 541-744-8441                  Join us for a hard hat tour
                                                                     connections. Join in for a hike,   Interested in joining an
                                 of the new Eugene Family
                                                                     yoga, spin, and more. See insert   LCMS Committee to make
Stephen Peirce, MD               YMCA facility on April
                                                                     for details.                       a bigger impact? Options
Physical Medicine & Rehab        20th. Space is limited to the                                          include Community Health,
Pacific Sports & Spine                                               HIV Alliance Big Night             PWP, and Membership
                                 first 15 registrants. Email info@   2023 fundraiser is set for
217 Division Ave                 lcmedsociety.com to add your                                           & Events. Email info@
Eugene 97404                                                         May 19th from 5:30-8:00pm          lcmedsociety.com for more
                                 name to the list.                   at the Farmer’s Market
P: 541-780-6654                                                                                         information or to apply.
F: 541-780-6645                  The Youth Leadership                Pavilion. For more information
                                 Committee at Positive               or to purchase tickets, visit
Rishi Vora, DO
Physical Medicine & Rehab
                                 Community Kitchen
                                 is hosting their annual
                                                                     www.hivalliance.org/event/big-
                                                                     night.
                                                                                                           Classified
Pacific Sports & Spine           fundraiser themed
                                                                     Sign up now for the
                                                                                                           Advertising
217 Division Ave                 “After School Snacks: A
Eugene 97404                     Cookoff for a Cause” April          66th Annual LCMS Golf                 CUSTOM
P: 541-780-6654                  25th from 6-8pm at the              Tournament. This year, we’ll          SUNRIVER HOME:
F: 541-780-6645                  Farmer’s Market Pavilion            be fundraising for Veterans           3 BR, 3 BA, den with
                                 in downtown Eugene.                 Legacy and Camp Alma with             Q futon + sleep/play
Events                           There will also be a raffle, live   the goal of beating last year’s
                                                                     donation of over $10,000. Grab
                                                                                                           loft. Sleeps 6. 4 flat
                                 music, and more. For tickets                                              screen TVs, 2 DVD
The Knight Campus                and information, visit www.         your foursome and register            players, Wi-Fi, new gas
presents Precision Medicine      positivecommunitykitchen.org.       today. All members welcome!           cooktop, gas barbeque,
for Better Bones with                                                                                      fireplace, bikes, 2 car
Dr. Danielle Benoit on                                                                                     garage, hot tub, private
Tuesday, April 11th from                                                                                   setting by Nat’l forest.
6:30-8:00pm at the John                                                                                    $325 + cleaning. No
G. Shedd Institute for the
Arts. This event is free and              Physician Wellness                                               smoking. Call Carol
                                                                                                           Berkman – cell: 541-
open to the public. Register
at accelerate.uoregon.edu/                 Program (PWP)                                                   953-5430.
                                                                                                           FREELANCE
science-knight-out.
                                                                                                           WRITERS NEEDED:
The Women Physicians                     Free & Confidential Help is Available                             LCMS is looking
                                                                                                           for freelance writers
Group will gather on April                    Through Cascade Health                                       to connect with
12th from 5:30-7:30pm
at KidsFirst. For more                       To schedule an                                                members, community
information, contact Shannon            appointment or access the                                          organizations, and
O’Leary at catalystbcandc@                                                                                 more. Pay starts at
gmail.com.
                                          24-hour support line,                                            $100/article based on

OMA Day at the Capitol
                                        Call 541-345-2800                                                  specifications. Email
                                                                                                           info@lcmedsociety.com.
is scheduled for Monday,

26 MEDICA L M ATTERS | A PRIL 2023
MEDICAL
                                            Postage         PRSRT STD      NONPROF
                                PLACE     Required.         US POSTAGE      US POS
                                         Post Office
                                STAMP   will not deliver
                                                                PAID            PAI
                      MATTERS    HERE   without proper      EUGENE, OR       EUGEN
                                           postage.        Permit
                                                           Permit No.
                                                                  No.921
                                                                      17    Permit N
Lane County Medical Society
        PO Box 7192
    Springfield, OR 97475

     Change Service Requested

       April 2023
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