Investor Presentation January - March 2021 - Smith+Nephew

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Investor Presentation January - March 2021 - Smith+Nephew
Investor Presentation
January – March 2021
Investor Presentation January - March 2021 - Smith+Nephew
Forward looking statements and non-IFRS measures

This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth
and trading profit margins, market trends and our product pipeline are forward-looking statements. Phrases such as "aim", "plan", "intend", "anticipate",
"well-placed", "believe", "estimate", "expect", "target", "consider" and similar expressions are generally intended to identify forward-looking statements.
Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially
from what is expressed or implied by the statements. For Smith+Nephew, these factors include: risks related to the impact of COVID-19, such as the depth
and longevity of its impact, government actions and other restrictive measures taken in response, material delays and cancellations of elective procedures,
reduced procedure capacity at medical facilities, restricted access for sales representatives to medical facilities, or our ability to execute business continuity
plans as a result of COVID-19; economic and financial conditions in the markets we serve, especially those affecting health care providers, payers and
customers (including, without limitation, as a result of COVID-19); price levels for established and innovative medical devices; developments in medical
technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls or other problems with quality
management systems or failure to comply with related regulations; litigation relating to patent or other claims; legal compliance risks and related
investigative, remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers (including, without limitation, as a
result of COVID-19); competition for qualified personnel; strategic actions, including acquisitions and dispositions, our success in performing due diligence,
valuing and integrating acquired businesses; disruption that may result from transactions or other changes we make in our business plans or organisation to
adapt to market developments; relationships with healthcare professionals; reliance on information technology and cybersecurity; and numerous other
matters that affect us or our markets, including those of a political, economic, business, competitive or reputational nature. Please refer to the documents
that Smith+Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including
Smith+Nephew's most recent annual report on Form 20-F, for a discussion of certain of these factors. Any forward-looking statement is based on information
available to Smith+Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith+Nephew are qualified by
this caution. Smith+Nephew does not undertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances or
in Smith+Nephew's expectations. The terms ‘Group’ and ‘Smith+Nephew’ are used for convenience to refer to Smith & Nephew plc and its consolidated
subsidiaries, unless the context requires otherwise.

Certain items included in ‘trading results’, such as trading profit, trading profit margin, tax rate on trading results, trading cash flow, trading profit to cash
conversion ratio, EPSA, leverage ratio, and underlying growth are non-IFRS financial measures. The non-IFRS financial measures in this announcement are
explained and reconciled to the most directly comparable financial measure prepared in accordance with IFRS in our Fourth Quarter and Full Year 2020
Results announcement dated 18 February 2021.                                                                                                                     2
Investor Presentation January - March 2021 - Smith+Nephew
Our history
                                                                                                                                          1914
                                       1856                                              1896                                Days after the outbreak of WW1,
                               Thomas James Smith                                 Horatio Nelson Smith                       we received an order to provide
                           opened a chemist shop in Hull,                        entered into apartnership                      surgical and field dressing
    1856                   UK and develops a new method                            with his uncleforming                           supplies to French                                                             From 50
Smith+Nephew                   for refining cod liver oil                           TJ Smith & Nephew                             army within 5 months                                                            To1200
 established                                                                                                                                                                         During WW1, staff grew
                                                  1986                                                                                                                                  from 50 to 1,200
                               Key acquisitions of Richards Medical Company
                               in Memphis, specialists in orthopaedic products                                                                                       1937
                                  and DYONICS, an arthroscopy specialists                                                                                     We were listed on the
                                              based in Andover                                                                                               London stock exchange
                                                                                                                 1953                                                                                 1928
                                                                                                   We developed a special low-temperatureplaster                                                  We produced an
                        1995                                                                       for the Everest climbers on the 1953 expedition.                                             experimental bandage
                       Acquired                                                                It enabled them to send back their camera films, sealed                                            ElastoplastTM
               Acufex Microsurgical Inc,                                                       and airtight!. This same research led to the development
              making us a market leader in                                                                  of importantindustrial products
              arthroscopic surgical devices
                                                                         1999                                                                                                            2001
                                                        We were listed on the New York Stock                                                                                OXINIUM , a new material that
                                                                                                                                                                                     ◊

                                                      Exchange and in 2001 became a constituent                                                                          improves performance and increases
                                                          member of the UK FTSE-100 index                                                                                     the service life of total joint
                                                                                                                                                                         replacement systems, firstintroduced

                        2014                                                                 2013                                            2011
               Acquired Arthrocare Corp.                                JOURNEY II BCS sets a new standard inknee
                                                                                     ◊                                       PICO , the first pocket-sized, single-use
                                                                                                                                  ◊

                 to expand our sports                                        implant performance,designed                      system, revolutionizes the negative
                   medicine portfolio                                         to empower patients to return                      pressure wound therapymarket
                                                                                   to an activelifestyle
                                                        17,500+                                                                                                                                 Over
                                                                                                                                                                                                100
                                                                                                                                                                                                                Today
                        2019                                              2020                                                                                                                                  and growing
            Expanding in technologies of the                   We are proud of what we do                     We exist to restore people’s bodies and their self-belief
            future, investing inOrthopaedics,                and value our 17,500 employees                     by using technologies to take the limits off living.
               Biologics and Digital Surgery.                    who make thispossible                                 We call this purpose “LifeUnlimited”

 ◊Trademark of Smith & Nephew, ©2020 Smith & Nephew                                                                                                                                                                           3
100                     FTSE 100
                        A constituent of the UK’s
                        FTSE 100, with ADRs
                                                    Shares
                                                    S+N has a progressive
                                                    dividend policy, and has
Smith+Nephew is a
                        traded on the New York      paid a dividend every
portfolio medical
                        Stock Exchange              year since 1937
technology business
that has been trading
for over 160 years,
and operates in more
than 100 countries      $4.6bn                      ~18,000
                        Annual sales in 2020        We have around 18,000
                        were $4.6 billion           employees globally

                                                                               4
A portfolio medical technology business

        ALLEVYN◊ LIFE                                                                      PICO◊
        Advanced Foam             Advanced                      Advanced        Negative Pressure
        Wound Dressings           Wound Care                    Wound Devices     Wound Therapy

                                                                                JOURNEY◊ II BCS
        Collagenase            Advanced                                              Bi-Cruciate
        SANTYL◊ Ointment       Wound                                                  Stabilised
        Enzymatic debrider     Bioactives                            Knees         Knee System

                                 ENT              $4.6bn
                               Arthroscopic      Revenues                                 OR3O◊
                                                                                    Dual Mobility
        COBLATION◊             Enabling                (2020)         Hips
        Wand                   Technologies

                                                                                    EVOS◊ SMALL
        REGENETEN◊             Sports Medicine                                     Plating System
        Bioinductive Implant
                               Joint Repair      Other Recon    Trauma
                                                 CORI◊
                                                 Surgical
                                                 System
                                                                                                    5
Leading positions in attractive markets

               Hip & Knee Implants                                                            Sports Medicine                                            Advanced Wound Management

                   $12.6bn market                                                             $4.6bn market                                                            $9.1bn market
            +2% 2017-19 average growth                                                +5% 2017-19 average growth                                                   +5% 2017-19 average growth
                -15% 2020 growth                                                          -12% 2020 growth                                                              -3% 2020 growth

                  Others                                                                 Others                                                                                         3M
                   15%                                                                    17%                                                                                          19%
                                                   Zimmer
   Smith+                                          Biomet
   Nephew                                           33%                                                                                                      Others
                                                                                Stryker                                       Arthrex
    11%                                                                                                                                                       51%
                                                                                 11%                                           33%                                                           Smith+
                                                                                                                                                                                             Nephew
                                                                                                                                                                                              14%
                                                                                    DePuy
                                                                                    Mitek 1                              Smith+                                                         Molnlycke
           DePuy                                                                                                                                                                           9%
                                                                                     13%                                 Nephew
          Synthes 1                           Stryker                                                                                                                             Convatec
            19%                                22%                                                                        26%
                                                                                                                                                                                    7%

                       #4 position                                                                #2 position                                                            #2 position

Data used in 2020 estimates generated by Smith+Nephew is based on publicly available sources and internal analysis and represents an indication of market shares
1 A division of Johnson & Johnson.                                                                                                                                                                    6
Our performance

                                     Revenue                                                           Trading profit                   Trading cash conversion
                $4,560m                           -12.1%*                               $683m                         15.0% margin   101%

                                                   5138                                                               1169                                         101%
                                        4904                                                                   1123
                              4765                                                        1020      1048                                     90%     85%
                   4669                                                                                                                                     83%
                                                             4560                                                                     75%
                                                                                                                             683

                   2016       2017      2018       2019      2020                         2016      2017       2018   2019   2020     2016   2017    2018   2019   2020

                Adjusted earnings per share (EPSA)                                                 Dividend per share                               Net debt
                64.6¢                                                                  37.5¢                                         $1,926m**
                                                                                                               36.0   37.5   37.5
                                       100.9      102.2                                              35.0
                              94.5                                                        30.8                                                                     1926
                   82.6
                                                                                                                                      1550                  1600
                                                             64.6                                                                            1281
                                                                                                                                                     1104

                   2016      2017       2018      2019       2020                         2016      2017       2018   2019   2020     2016   2017    2018   2019   2020

* Underlying growth percentage after adjusting for the effect of currency translation, acquisitions and disposals.
** 2020 net debt includes lease liabilities.                                                                                                                              7
Priorities for 2021

Footer                8
Priorities for 2021 – Strategy and COVID

           Return to top-line growth and
     1
           recapture momentum

           Drive further operational
     2
           improvement

           Continue to respond effectively
     3
           to COVID

                                             9
Return to top-line growth and recapture momentum

     What we have achieved                       Driving sustainable revenue growth

                                   Maximising portfolio potential
                                   • Driving higher return from portfolio and growing recent launches
 Clear strategy for growth
                                   • Continuing to drive commercial excellence across franchises
 •    New commercial model
 •    New commercial leadership
 •    Portfolio enhanced through   Delivering value of the acquired assets
      M&A                          • Driving synergistic growth in Trauma & Extremities, Joint Repair, ENT and
                                     Bioactives
                                   • Adding further value-creating opportunities focused on high growth
 Investment in innovation
                                     segments
 •    Step up in R&D investment

                                   Launching expanded pipeline of innovation
 New Leadership Team
                                   • High cadence of product launches across the franchises
                                   • Further increase in R&D investment

                                                                                                                 10
Delivering pipeline of innovation
Key late stage projects

                                                               Recently launched
                                                                                                                                     Key 2021 projects*
                                                                growth drivers

                                                              OR3O Dual mobility                                Porous Knee system               Porous offering for Knee portfolio
                                     Hip & Knee
                                     implants                 HARMONY Modular Trays                             New Hip & Knee instruments       Streamlined instrument set for THA and TKA

                                                                                                                ARIA Home PT                     Remote physical therapy module
                                     Robotics & digital       CORI TKA
 Orthopaedics                        surgery                  Hip 7 Navigation on Kick
                                                                                                                RI.HIP Navigation on CORI        Navigation assisted Hip procedures
                                                                                                                CORI Tensioner                   Tissue balancing for robotic-assisted TKA

                                                                                                                EVOS Large Frag/Periprosthetic   Broadening EVOS trauma plate portfolio
                                     Trauma &
                                     Extremities                                                                Digital Taylor Spatial Frame     Increased efficiency in External fixation

                                     Sports Medicine          HEALICOIL Knotless PEEK                           FASTFIX FLEX                     Next generation meniscal repair
                                     Joint Repair             Hip Capsular Blades/Hip Pack                      REGENETEN Expansion              Product and region expansion
 Sports
                                     Arthroscopic Enabling
 Medicine &                          Technologies
                                                              INTELLIO Connected Tower                          DOUBLEFLO                        Arthroscopic tower fluid management

 ENT                                                          HALO WEREWOLF ENT Wand
                                     ENT
                                                              TULA

                                    Advanced Wound
                                                              Clinical Decision Support
                                    Care
 Advanced                                                                                                       GRAFIX, PL XC & PL CORE          Lyopreserved biotissue
                                    Advanced Wound
 Wound                              Bioactives
                                                                                                                STRAVIX, PL & MESHED             Lyopreserved biotissue
 Management                                                                                                     PICO PROTECT                     Next generation single-use NPWT
                                    Advanced Wound            PICO Region and Indication
                                    Devices                   Expansion                                         LEAF 2.0                         Next generation Patient monitoring system

Blue indicates products from recent acquisitions
*All innovation launches coming after completing relevant regulatory review, clearance and approval processes
                                                                                                                                                                                              11
Demonstrated launch excellence
Growth inflections from new products in recent years
                         US Hips growth vs peers                                                         Sports Medicine Joint Repair
                                                                                                              quarterly growth
                                                                                                                                                       14.0%
                                               9.8%
     3.9%                                                 4.4%
                                                                                                              REGENETEN
                   -5.4%                                                                                   acquired end 2017
                                                                                                                                     8%
  OR3O launch
                              -28.9%                                                                            6%
    Q4 2019

                                                                    OR3O Dual Mobility                                                                              REGENETEN
                                                                                                                                                                    Bioinductive Implant

     Q4 2019        Q1 2020        Q2 2020     Q3 2020    Q4 2020                              Q1 2017    Q3 2017   Q1 2018    Q3 2018   Q1 2019   Q3 2019

                   AET quarterly growth                                                                       PICO annual sales
                                      FLOW 90
                                   launch Q2 2019
                                                         5.1%
                                   LENS 4K launch
                                      Q3 2019                       FLOW 90 Wand
                                                0.8%

                         -1.1%
   -2%                               -2.1%

                -4%
                                                                    LENS 4K
                                                                                                                                                                       PICO 7 sNPWT
  Q3 2018      Q4 2018   Q1 2019     Q2 2019   Q3 2019   Q4 2019    Surgical Imaging System   2011           2013             2015          2017             2019

                                                                                                                                                                                           12
Drive further operational improvement
Operations transformation and process efficiencies

                                   •   Continuing manufacturing network optimisation
   Operations transformation       •   Outsourcing of warehousing and distribution
                                   •   Process transformation, with Lean deployment and greater automation

                                   •   Simplify end-to-end processes
   Process efficiencies            •   Improve commercial execution and product launches
                                   •   Invest in IT and Digital solutions

                     •    Five year operations efficiency plan, with work started in late 2019
                     •    Targeting c.$200m of annualised cost savings
                     •    Restructuring costs of c.$350m in total, by end of 2023

                                                                                                             13
Continue to respond effectively to COVID

           Customers                       Employees                   Cost control

  •   Support customers in         •   Flexible and updated      •   Control discretionary
      person and remotely              working environments          costs while COVID
                                                                     outbreak continues
  •   Transform medical            •   COVID secure sites with
      education, with new online       deployment of social
      platform in 2021                 distancing technology

                                                                                             14
2021 outlook

•   COVID-19 impact expected to continue into H1 2021, timing of
    recovery unclear

•   We expect substantial underlying revenue growth compared to
    2020, with faster recovery in Established Markets
     − Hips to continue to outperform Knees
     − Sports Medicine & ENT to rebound strongly
     − AWM growth trajectory to improve

•   Trading margin elements compared to 2019:
     − Ongoing COVID-19 impact on gross margin
     − Dilution from investment in R&D (c.100bps), M&A (c.150bps)
     − FX headwind (c.100bps)

•   Tax rate on trading results in the range of 18-19%

                                                                    15
Sustainability targets

               People                                   Planet                                Products

Creating a lasting positive impact       A medical technology business            Innovating sustainably
on our communities                       with a positive impact
                                                                                  By 2022, include sustainability review
Between 2020 and 2030, contribute        Achieve an 80% absolute reduction in     in New Product Development phase
1 million volunteer hours to the         total life cycle greenhouse gas          reviews for all new products and
communities in which we live and         emissions by 2050, beginning by          product acquisitions.
work.                                    implementing 100% renewable              By 2025, incorporate at least 30%
                                         electricity (e.g. solar or wind) plans   post-consumer recycled content into
Empower and promote the inclusion
                                         at our facilities in Memphis (US) and    all packaging materials.
of all.
                                         Malaysia by 2022, and at all of our
                                         strategic manufacturing facilities by    By 2025, complete supply chain
                                         2025.                                    assessment of all suppliers and
 To check our progress, please view                                               subsequent tier levels to assure
 the Annual Sustainability Report on     Achieve zero waste to landfill at        compliance with our sustainability
      Smith+Nephew’s website.            our facilities in Memphis (US) and       requirements.
                                         Malaysia by 2025 and at all of our
   www.smith-nephew.com/sustainability   strategic manufacturing facilities by
                                         2030.

                                                                                                                        16
Financials

             17
Q4 revenue:
$1,326m, -7.1% underlying, -5.8% reported

                           Revenue split                                          Product franchise growth

           Emerging Markets
               $212m
                                                                Orthopaedics                                             -10.2%
                                                                Knees                                                  -16.2%
                                               US
                                             $689m              Hips                                                               -0.5%

             Other                                              Other Recon                          -45.6%
     Established Markets                                        Trauma                                                             -1.3%
            $425m

                                                                Sports Medicine, ENT                                            -5.2%

                     Geographical growth                        Sports Medicine Joint Repair                                       -0.3%
                                                                Arthroscopic Enabling Technologies                              -5.0%
                 -7.1%              Global
                                                                ENT                                           -33.1%

                                                                Advanced Wound Management                                       -4.4%
                      -4.9%         US                          AWC                                                               -2.1%
                                                                AWB                                                        -9.9%
                   -6.2%            Other Established Markets
                                                                AWD                                                                        +0.2%

 -14.9%                             Emerging Markets

                                                                                                                                                   18
FY revenue:
$4,560m, -12.1% underlying, -11.2% reported

                               Revenue split                                          Product franchise growth

               Emerging Markets
                   $771m
                                                                    Orthopaedics                                       -14.0%
                                                                    Knees                                         -21.0%
                                                     US
                                                  $2,339m           Hips                                                            -7.4%

                 Other                                              Other Recon                             -26.1%
         Established Markets                                        Trauma                                                            -5.1%
              $1,450m

                                                                    Sports Medicine, ENT                                   -13.0%

                         Geographical growth                        Sports Medicine Joint Repair                              -10.2%
                                                                    Arthroscopic Enabling Technologies                      -12.4%
         -12.1%                         Global
                                                                    ENT                                  -29.7%

                                                                    Advanced Wound Management                                   -8.1%
              -10.1%                    US                          AWC                                                             -7.5%
                                                                    AWB                                                      -10.5%
         -12.3%                         Other Established Markets
                                                                    AWD                                                                -4.8%

-16.8%                                  Emerging Markets

                                                                                                                                               19
2020 quarterly underlying sales development by region

                                                    Other established
                     US                                                                   Emerging markets
                                                        markets

   •   Limited restrictions on elective        •   Overall performance stable from    •   Continued strong end-user
       surgery reintroduced in some                Q3, with mixed trends by market        demand in China
       states
                                               •   UK and Japan strengthened;         •   Latin America and India remain
   •   Patient cancellations due to positive       France and Italy slowed                under significant restrictions,
       COVID tests and staff shortages                                                    some improvement in South
       also affected surgery volumes           •   New restrictions in some markets       Africa
                                                   into 2021

                                                                                                                            20
Full year revenue by franchise

                                     2020    2019    Reported   Underlying
                                      $m      $m      growth     growth
        Group                        4,560   5,138   (11.2%)    (12.1%)

         Orthopaedics                1,917   2,222   (13.7%)     (14.0%)
         Sports Medicine & ENT       1,333   1,536   (13.2%)     (13.0%)
         Advanced Wound Management   1,310   1,380   (5.1%)      (8.1%)

                                                                             21
Full year trading income statement

                                              2020      2019      Reported   Underlying
                                               $m        $m        growth     growth
       Revenue                                4,560     5,138     (11.2%)    (12.1%)
       Cost of goods sold                     (1,375)   (1,326)
       Gross profit                           3,185     3,812     (16.4%)
       Gross profit margin                    69.9%     74.2%

       Selling, general and admin             (2,223)   (2,375)
       Research and development               (279)     (268)
       Trading profit                          683      1,169     (41.6%)
       Trading profit margin                  15.0%     22.8%

       IFRS operating profit                   295       815      (63.8%)
       IFRS operating profit margin           6.5%      15.9%

       Adjusted earnings per share ("EPSA")   64.6¢     102.2¢    (36.8%)
       Earnings per share ("EPS")             51.3¢     68.6¢     (25.2%)
       Dividend per share                     37.5¢     37.5¢        -

                                                                                          22
Trading profit margin

                        23
Full year free cash flow

                                                       2020    2019
                                                        $m      $m
         Trading profit                                683     1,169

         Share based payment                            26      32
         Depreciation and amortisation                 397     368
         Lease liability repayments                    (55)    (46)
         Capital expenditure                           (443)   (408)
         Movements in working capital and other         82     (145)
         Trading cash flow                             690     970
         Trading cash conversion                       101%    83%

         Restructuring, acquisition, legal and other   (216)   (54)
         Net interest paid                             (59)    (52)
         Taxation refunded/(paid)                       22     (150)
         Free cash flow                                437     714

                                                                       24
Net debt and capital allocation

  *Net debt includes lease liabilities
                                         25
Appendices

             26
Technical guidance

                                                                                  February 2021

        Foreign exchange and acquisitions
        Translational FX impact on revenue growth(1)                                  2.8%
        Acquisition impact on revenue growth                                          1.7%
        Non-trading items
        Restructuring costs                                                        $140-150m
        Acquisition and integration costs                                           $35-45m
        European Medical Device Regulation (MDR) compliance costs                    c. $60m
        Other
        Amortisation of acquisition intangibles                                    $170-180m
        Income from associates                                                       c. $5m
        Net interest(2)                                                             $75-80m
        Other finance costs                                                          c. $15m
        Tax rate on trading result                                                  18-19%

        (1) Based on the foreign exchange rates prevailing on 5th February 2021
        (2) Includes interest associated with IFRS 16 Leases

                                                                                                  27
Franchise revenue analysis
                                                                                    2019                                                                              2020
                                                                                                                 Full                                                                                     Full
                                                        Q1            Q2            Q3             Q4                            Q1            Q2             Q3            Q4           Full Year
                                                                                                                 Year                                                                                     Year
                                                      Growth        Growth        Growth         Growth                        Growth        Growth         Growth        Growth         Revenue
                                                                                                                Growth                                                                                   Growth
                                                        %             %             %              %                             %             %              %             %               $m
                                                                                                                  %                                                                                        %
 Orthopaedics                                           3.9           3.6            3.4           5.1            4.0           (8.3)        (34.0)          (2.8)        (10.2)          1,917          (14.0)
 Knee Implants                                          4.1            4.3           4.6            4.7            4.4          (10.6)        (46.9)         (9.5)         (16.2)           822          (21.0)
 Hip Implants                                           2.4            2.9           2.6            0.7            2.1          (8.6)         (26.9)           7.1          (0.5)           567          (7.4)
 Other Reconstruction                                   6.9            3.5           1.5           31.6           12.6           19.4         (51.5)         (3.1)         (45.6)            68          (26.1)
 Trauma                                                 4.8            2.8           2.2            7.0            4.3          (7.1)         (11.1)         (1.4)          (1.3)           460          (5.1)
 Sports Medicine & ENT                                  5.3           5.6            6.9          10.1            7.0           (9.5)        (33.3)          (4.5)         (5.2)          1,333          (13.0)
 Sports Medicine Joint Repair                          11.0           11.9          12.2           14.0           12.3          (7.1)         (32.0)         (2.7)          (0.3)           710          (10.2)
 Arthroscopic Enabling
                                                       (1.1)         (2.1)           0.8            5.1            0.8          (11.2)        (32.1)         (1.6)          (5.0)           517          (12.4)
 Technologies
 ENT                                                    4.2            6.3           5.3           10.7            6.7          (15.2)        (44.0)        (24.8)         (33.1)           106          (29.7)
 Advanced Wound Management                              4.1           1.2            2.1           1.9            2.2           (4.0)        (17.6)          (6.1)         (4.4)          1,310          (8.1)
 Advanced Wound Care                                    2.4          (1.3)          (2.3)           0.4          (0.2)          (6.7)         (14.6)         (6.9)          (2.1)           647          (7.5)
 Advanced Wound Bioactives                             (0.7)         (1.9)           2.8          (1.9)          (0.4)          (8.6)         (18.7)         (4.5)          (9.9)           431          (10.5)
 Advanced Wound Devices                                16.6           16.3          15.4           15.4           15.9           13.0         (23.7)         (6.9)           0.2            232          (4.8)
 Total                                                  4.4           3.5            4.0           5.6            4.4           (7.6)        (29.3)          (4.2)         (7.1)          4,560          (12.1)

All revenue growth rates are on an underlying basis and without adjustment for number of selling days.
                                                                                                                                                                                                                  28
The 2019 growth rates for the Advanced Wound Care, Advanced Wound Bioactives and Advanced Wound Devices franchises have been re-presented in order to present consistent analysis to the 2020 results.
There has been no change in growth for the Advanced Wound Management franchise or the total Group in any period for 2019.
Regional revenue analysis

                                                                              2019                                                            2020
                                                Q1              Q2             Q3             Q4        Full Year     Q1       Q2       Q3        Q4     Full Year   Full Year
                                              Growth          Growth         Growth         Growth       Growth     Growth   Growth   Growth    Growth   Revenue      Growth
                                                %               %              %              %            %          %        %        %         %         $m          %
  US                                             4.0            2.3            2.7            4.2         3.3       (4.7)    (31.8)    0.9       (4.9)    2,339       (10.1)
  Other Established Markets(1)                  (0.1)          (1.3)          (0.3)           2.4         0.2       (6.3)    (30.8)   (6.2)      (6.2)    1,450       (12.3)
  Established Markets                            2.2            0.9            1.5            3.5         2.1       (5.4)    (31.4)   (1.8)     (5.4)     3,789      (11.0)

  Emerging Markets                              15.3           16.2           16.0           16.6        16.1       (17.9)   (20.2)   (14.5)    (14.9)     771       (16.8)
  Total                                          4.4            3.5            4.0            5.6         4.4       (7.6)    (29.3)   (4.2)     (7.1)     4,560      (12.1)

(1) Other Established Markets’ are Australia, Canada, Europe, Japan and New Zealand.
All revenue growth rates are on an underlying basis and without adjustment for number of selling days

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Trading days per quarter

                   Q1      Q2   Q3   Q4   Full year

         2019      63      63   63   62     251
         2020      62      63   63   64     252
         2021      64      64   63   60     251
         2022      63      64   63   60     250

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