IMMUNOLOGY2021TM VIRTUAL - CALL FOR ABSTRACTS
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CALL FOR ABSTRACTS VIRTUAL IMMUNOLOGY2021 TM More science, more time, your way AAI ANNUAL MEETING | MAY 10–15, 2021 A FULLY ONLINE EXPERIENCE WWW.IMMUNOLOGY2021.ORG 1 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
PRESIDENTS’ PROGRAMS
Due to the cancellation of IMMUNOLOGY2020TM, both
Dr. Ting and Dr. Boss will have a president’s program at
Virtual IMMUNOLOGY2021TM.
2021 AAI President’s Address
The All-Encompassing Importance of
Innate Immunity
Jenny P. Ting, Univ. of North Carolina, Chapel Hill
AAI President (2020–2021)
Introduction
Jeffrey A. Frelinger, Univ. of Arizona and Univ. of North
Jenny P. Ting
Carolina, Chapel Hill
2021 AAI President’s Symposium
The Impact of Immunology on Health and
Diseases: As Far as the Eye Can See
Chair
Jenny P. Ting, Univ. of North Carolina, Chapel Hill
AAI President (2020–2021)
Speakers
Etty (Tika) N. Benveniste, Univ. of Alabama,
Birmingham Etty (Tika) N. Benveniste Mary N. Carrington
Neutrophil involvement in autoimmune
neuroinflammation
Mary N. Carrington, NCI, NIH
The impact of immunogenetic variation on functional
characteristics of the immune response
Blossom A. Damania, Univ. of North Carolina, Chapel Hill
Modulation of host immunity by human herpesviruses
Laurie H. Glimcher, Dana Farber Cancer Inst.
Blossom A. Damania Laurie H. Glimcher
Stressed out: a novel approach to cancer immunotherapy
2 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
PRESIDENTS’ PROGRAMS
2020 AAI President’s Address
The Regulation of Immunity
Presentation of AAI Lifetime Achievement Award to
Marc K. Jenkins
Jeremy M. Boss, Emory Univ. Sch. of Med.
AAI President (2019–2020)
Introduction
Peter E. Jensen, Univ. of Utah
2020 AAI President’s Symposium
Genes and Genomes in Healthy and Jeremy M. Boss
Autoimmune Lymphocytes
Presentation of AAI Excellence in Mentoring Award to
Jeffrey A. Bluestone
Chair
Jeremy M. Boss, Emory Univ. Sch. of Med.
AAI President (2019–2020)
Speakers
Michael S. Krangel, Duke Univ. Med. Ctr.
RAG expression and TCR repertoire formation in double
positive thymocytes
Michael S. Krangel Frances E. Lund
Frances E. Lund, Univ. of Alabama, Birmingham
Inflammatory cytokine-mediated control of effector
memory B cell development and function
Eugene M. Oltz, The Ohio State Univ. Col. of Med.
Wiring schemes for innate and adaptive
lymphoid cells
Max D. Cooper, Emory Univ. Sch. of Med.
The evolution of T and B cells
Eugene M. Oltz Max D. Cooper
3 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
DISTINGUISHED LECTURES
The 2021 Distinguished Lectures Program is dedicated to the memory of Dr. Wendy Havran. Dr. Havran was selected
as a Distinguished Lecturer for IMMUNOLOGY2020TM but she unfortunately died after a brief illness in January 2020.
A tribute to her exemplary service to AAI, and to her life and work, may be read at www.aai.org/tribute.
Michael P. Cancro Dario A. A. Vignali Donna L. Farber
Univ. of Pennsylvania Perelman Univ. of Pittsburgh Sch. of Med. Columbia Univ. Med. Ctr.
Sch. of Med. Immune inhibitory mechanisms Human immunity in space and time
A tale of two subsets: rethinking B cell in cancer
selection, homeostasis, and memory
CAREER AWARDS
Each year AAI recognizes the extraordinary professional achievements and career promise of its members. The following
are the recipients of the 2020 AAI Career Awards being presented at Virtual IMMUNOLOGY2021TM.
AAI Lifetime AAI Distinguished AAI Excellence in
Achievement Award Service Award Mentoring Award
Presented prior to Dr. Boss’s Presented at the Presented prior to Dr. Boss’s
President’s Address Business Meeting President’s Symposium
Recognizes a member for a Recognizes a member for outstanding Recognizes a member for exemplary
career of extraordinary scientific service to the AAI community and the career contributions to a future
achievement and exceptional field of immunology generation of scientists
leadership and service to AAI
Marc K. Jenkins Juan Carlos Zúñiga-Pflücker Jeffrey A. Bluestone
Univ. of Minnesota Ctr. Univ. of Toronto and Sunnybrook Univ. of California, San Francisco,
for Immunology Res. Inst., Canada and Sonoma Biotherapeutics
4 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
AAI-BD Biosciences Investigator AAI-BioLegend Herzenberg
Award Presentation and Lecture Award Presentation and Lecture
Recognizes an early-career investigator who has made Recognizes an individual who has made exemplary
outstanding contributions to the field of immunology research contributions to the field of B cell biology
Erika L. Pearce Susan K. Pierce
Max Planck Inst. of Immunobiology and NIAID, NIH
Epigenetics, Germany; Bloomberg-Kimmel Inst. Regulators and influencers of B cell affinity
for Cancer Immunotherapy, Johns Hopkins Univ.
(as of January 1, 2021)
Metabolic regulation of T cell function
AAI-Thermo Fisher Meritorious Career AAI-Steinman Award for Human
Award Presentation and Lecture Immunology Research
Recognizes a mid-career scientist for outstanding Presentation and Lecture
research contributions to the field of immunology Recognizes an individual who has made significant
contributions to the understanding of immune
Alexander Y. Rudensky
processes underlying human disease pathogenesis,
HHMI, Mem. Sloan Kettering Cancer Ctr.,
prevention, and therapies
Rockefeller Univ., and Weill Cornell Med.
The virtue of restraint in adaptive immunity Michael J. Lenardo
NIAID, NIH
Identification of novel gene defects leads to precision
therapies for congenital immune diseases
5 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
MAJOR SYMPOSIA
Major Symposium A Major Symposium C
Modern World Influences of the Immunological Angle of the Brain and its Diseases
Microbiome and their Consequences for Chairs
Immune-Mediated Diseases Jonathan Kipnis, Washington Univ., St. Louis
Chairs Zsuzsanna Fabry, Univ. of Wisconsin Sch. of Med.
Cathryn Nagler, Univ. of Chicago
Speakers
Barbara Rehermann, NIDDK, NIH
Zsuzsanna Fabry, Univ. of Wisconsin Sch. of Med.
Speakers Dendritic cells link neuroinflammation and
Barbara Rehermann, NIDDK, NIH lymphangiogenesis in the brain
Natural vs. laboratory world: wild mouse microbiota Antoine Louveau, Lerner Res. Inst.
improve host fitness and preclinical models Regulation of brain maturation by the meningeal
Noah Palm, Yale Univ. lymphatic vasculature
Illuminating the ‘dark matter’ of the bioactive Isaac M. Chiu, Harvard Univ.
microbiota metabolome Role of neuro-immune interactions in bacterial host defense
June L. Round, Univ. of Utah Ashley Moseman, Duke Univ. Sch. of Med.
Microbe-immune interactions prevent obesity Coordinating CNS host defense following olfactory
Cathryn Nagler, Univ. of Chicago neuroinvasion
Intestinal bacteria regulate allergic responses to food Stanley Perlman, Univ. of Iowa
Neil Surana, Duke Univ. Coronavirus infections of the CNS and immunological
Microbiome engineering to treat inflammatory diseases responses
Beth Stevens, Boston Children’s Hosp.
Major Symposium B Mapping microglia states to function in health and disease
Host Immunity to Intracellular Pathogens
Chairs Major Symposium D
Phillip A. Scott, Univ. of Pennsylvania Sch. of Vet. Med Innate Immunity: The Good, The Bad, The Ugly
Shabaana Khader, Washington Univ., St. Louis Chairs
Speakers Clara Abraham, Yale Univ.
Phillip A. Scott, Univ. of Pennsylvania Sch. of Vet. Med. Katherine A. Fitzgerald, Univ. of Massachusetts Med. Sch.
Pathways promoting pathology: how CD8+ T cell cytolysis Speakers
influences disease outcome in cutaneous leishmaniasis Clara Abraham, Yale Univ.
Shabaana A. Khader, Washington Univ., St. Louis Modulation of innate immune responses by disease-
Role of innate lymphoid cells in tuberculosis associated genes
John T. Harty, Univ. of Iowa Katherine A. Fitzgerald, Univ. of Massachusetts Med. Sch.
T cell immunity in tissues Regulation of inflammation by nucleic acid-binding proteins
Manuela Raffatellu, Univ. of California, San Diego Daniel B. Stetson, Univ. of Washington
Mucosal immunity to Salmonella Innate immune detection of intracellular DNA
Melissa B. Lodoen, Univ. of California, Irvine Raphaela T. Goldbach-Mansky, NIAID, NIH
Innate immunity and pathogenesis in the vasculature Innate immune dysregulation in autoinflammatory diseases
during Toxoplasma gondii infection Gregory F. Sonnenberg, Weill Cornell Med.
Maziar Divangahi, McGill Univ., Canada Immune regulation of intestinal health
Hematopoietic stem cells: the target for vaccine or pathogen Kodi S. Ravichandran, Univ. of Virginia
Soothing messages on the way out: apoptotic cell
communication with the neighborhood
6 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
Major Symposium E Major Symposium G
Molecular Mechanisms of Tumor Immunity B Lineage Signals in Protective vs. Maladaptive
Chairs Antibody Responses
Thomas F. Gajewski, Univ. of Chicago Chairs
Lisa H. Butterfield, Parker Inst. for Cancer Mark R. Boothby, Vanderbilt Univ. Med. Ctr.
Immunotherapy Roberta Pelanda, Univ. of Colorado, Denver
Speakers Speakers
Thomas F. Gajewski, Univ. of Chicago Roberta Pelanda, Univ. of Colorado, Denver
Mechanisms of cancer immunotherapy efficacy vs. Molecular control of central B cell tolerance: is it one for all?
resistance Julie Zikherman, Univ. of California, San Francisco
Lisa H. Butterfield, Parker Inst. for Cancer Negative feedback regulation of normal and
Immunotherapy autoimmune B cell responses.
Cancer vaccines and what does and doesn’t matter João P. Pereira, Yale Univ.
Weiping Zou, Univ. of Michigan B cell circuits in homeostasis and disease
Metabolic impact on cancer immunity and therapy Pamela L. Schwartzberg, NIAID, NIH
Jennifer A. Wargo, Univ. of Texas MD Anderson Modulation of B cell responses by PI3K-delta
Cancer Ctr. Mark R. Boothby, Vanderbilt Univ. Med. Ctr.
The role of the microbiome in response and toxicity to therapy Imag(in)ing a fusion of nutrients, metabolism, and
Arlene H. Sharpe, Harvard Med. Sch. function as B cells effect antibody responses
Discovery of new immuno-oncology targets leveraging Michel C. Nussenzweig, HHMI, Rockefeller Univ.
CRISPR Human antibody responses to viral pathogens
Major Symposium F Major Symposium H
Engineering Immunity Stromal Cells Underpinning Immune Cell
Chairs Development and Function
Dennis Burton, Scripps Res. Chairs
Benjamin A. Youngblood, St. Jude Children’s Res. Hosp. Susan R. Schwab, New York Univ. Grossman Sch. of Med.
Speakers Juan Carlos Zúñiga-Pflücker, Univ. of Toronto and
Dennis Burton, Scripps Res. Sunnybrook Res. Inst., Canada
Neutralizing antibodies, neutralization, and vaccines Speakers
Laura M. Walker, Adimab, LLC Juan Carlos Zúñiga-Pflücker, Univ. of Toronto and
Broad and potent neutralizing antibodies to combat Sunnybrook Res. Inst., Canada
viral threats Thymus stromal cells are plastic
Darrell J. Irvine, MIT Mark S. Anderson, Univ. of California, San Francisco
The impact of vaccine kinetics on humoral immunity Maintenance of immune tolerance by thymic stromal cells
Alexander Marson, Univ. of California, San Francisco Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland
Reprogramming human T cells with CRISPR Fibroblastic reticular cells: subsets and functions
Benjamin A. Youngblood, St. Jude Children’s Res. Hosp. Susan R. Schwab, New York Univ. Grossman Sch. of Med.
Epigenetic reprogramming of CD8+ T cell differentiation Exit strategies: S1P and immune cell migration
potential Theresa T.-S. Lu, Hosp. for Special Surgery Res. Inst.
Anjana Rao, La Jolla Inst. for Immunology Langerhans cells and stromal regulation in lupus
Transcriptional and epigenetic regulation in anti-tumor Melody A. Swartz, Univ. of Chicago
responses Antigen presentation by lymphatic endothelial cells and
T cell memory
All session information is subject to change.
7 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
SPECIAL SESSIONS
Anthony S. Fauci Linda J. Saif De’Broski R. Herbert
COVID-19 and the Science of Pandemics— AAI Vanguard Lecture
Lessons Learned Presented by an AAI member selected by the Minority
Co-Chairs Affairs Committee for their scientific achievement and
David Masopust, Univ. of Minnesota, AAI Program exemplary career success.
Committee Chair
M. Michele Hogan, Executive Director, AAI Chair
Tonya J. Webb, Univ. of Maryland Sch. of Med., AAI
Speakers Minority Affairs Committee Chair
Anthony S. Fauci, Director, NIAID, NIH
Linda J. Saif, Distinguished University Professor, Speaker
The Ohio State Univ. De’Broski R. Herbert, Univ. of Pennsylvania Sch. of
Vet. Med.
IL-33 regulates the balance between inflammation
and immunosuppression
GUEST SESSIONS
(Past Participants)
American Society for Reproductive Immunology (ASRI) Japanese Society for Immunology (JSI)
The American Society of Transplantation (AST) Korean Association of Immunologists (KAI) and
The American Society of Tropical Medicine and Hygiene The Association of Korean Immunologist in America
(ASTMH) (AKIA)
Australasian Society for Immunology (ASI) National Institute of Allergy and Infectious Diseases
(NIAID, NIH)
Canadian Society for Immunology (CSI)
National Institute of Environmental Health Sciences
Center for Scientific Review (CSR, NIH)
(NIEHS, NIH)
Chinese Society for Immunology (CSI)
National Institute on Aging (NIA, NIH)
Chinese Society of Immunology, Taiwan (CSIT)
The Obesity Society (TOS)
European Federation of Immunological Societies (EFIS)
Society for Immunotherapy of Cancer (SITC)
German Society for Immunology (DGfI)
Society for Leukocyte Biology (SLB)
International Complement Society (ICS)
Society for Mucosal Immunology (SMI)
The International Cytokine and Interferon Society (ICIS)
Society for Natural Immunity (SNI)
International Society of Developmental and
Comparative Immunology (ISDCI)
8 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
COMMITTEE-SPONSORED SESSIONS AND EVENTS
AAI Committees host symposia, workshops, lectures, and events that address the most recent advances in their
specialty areas of immunology research, as well as issues in public policy and career development.
Clinical Immunology Committee Minority Affairs Committee
Transforming the Study of Human Disease through Chair: Tonya J. Webb, Univ. of Maryland Sch. of Med.
Systems Immunology • Panel Discussion: Minority Scientists’ Experiences:
Chair: Jennifer Anolik, Univ. of Rochester Med. Ctr. Challenging and Overcoming Barriers to Enhancing
Diversity and Career Advancement
Committee on Public Affairs
The U.S. COVID-19 Response: Successes, Failures, and • Careers Roundtables
Ongoing Challenges • AAI Vanguard Lecture
Chair: Ross M. Kedl, Univ. of Colorado Anschutz Sch. of Med. Program Committee
Committee on the Status of Women and Back to School: A Review of Four Fast-Moving Fields
Education Committee Chairs: David Masopust, Univ. of Minnesota; and
Careers in Science Roundtables Kimberly S. Schluns, Univ. of Texas MD Anderson
Chair: Laura A. Solt, Scripps Res. Cancer Ctr.
Education Committee Publications Committee
• Careers in Biotech Panel Discussion How to Write a Scientific Paper, Respond to Reviews, and
Chair: H. Kiyomi Komori, Arena Pharmaceuticals Disseminate Your Findings
Chair: Eugene M. Oltz, The Ohio State Univ. Col. of Med.,
• Immunology Teaching Interest Group
Editor-in-Chief, The Journal of Immunology
Chairs: Edith Porter, California State Univ., Los
Angeles, and Michelle A. Swanson-Mungerson, Veterinary Immunology Committee
Chicago Col. of Osteopathic Med., Midwestern Univ. Zoonotic Pandemics—Immune Factors Contributing to
Pathogenesis and Protection
Chair: Crystal L. Loving, Natl. Animal Dis. Ctr., ARS, USDA
For session details and presentations, visit www.IMMUNOLOGY2021.org/scientific-program.
CAREER DEVELOPMENT OPPORTUNITIES
In addition to committee-sponsored sessions, Virtual IMMUNOLOGY2021™ will provide the following career
development programs. AAI will also sponsor a Jobs Board during the meeting.
How to Convert Your CV into a Résumé NIH Grants Workshop: Demystifying the
Speaker: Derek Haseltine, Career Development Ctr., Grant Application Submission, Review,
Baylor Col. of Med.; Hertz Foundation (as of January 2021) and Funding Processes
Chair: Tina McIntyre, CSR, NIH
Interviewing for a Job
Speaker: Derek Haseltine, Career Development Ctr., How to Have a Successful Postdoctoral Experience
Baylor Col. of Med.; Hertz Foundation (as of January 2021) Speaker: Lori Conlan, Office of Postdoctoral Services, NIH
9 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORG
ABSTRACTS BLOCK SYMPOSIA
AAI invites the submission of abstracts that report • Outstanding abstracts will be programmed for oral
unpublished data from research developments in all presentation in Block Symposia. (Assigned times will
areas of immunology. Abstracts are welcome from be provided with acceptance notifications.)
scientists in all sectors—academia, government, • First authors will be required to upload their
and industry. To submit an abstract, please go to presentations. (Further instructions will be provided
www.IMMUNOLOGY2021.org/abstracts. with acceptance notifications.)
• All accepted abstracts will be presented in virtual • Authors presenting in Block Symposia must also
poster sessions. present a poster in a designated poster session.
• Authors will be present to discuss research results
during assigned poster times. These times will be
unopposed by other sessions.
POSTERS
• First authors of abstracts must register for the meeting • Posters will be available for viewing throughout
in order to present their work. (Details to follow with the meeting.
acceptance notifications.) • All poster presenters will be required to upload a PDF
• Submitting an abstract is not the same as of their poster. (Further instructions will be provided
registering for the meeting. To register, please with acceptance notifications.)
visit www.IMMUNOLOGY2021.org/registration • All poster presenters will be required to pre-record
by April 20, 2021. and upload a short presentation of their poster. This
should act like a guided presentation for attendees
Abstract Submission . . . . . . . . . . . . . . . . . Now Open as they view a poster. (Further instructions will be
Abstract Submission Closes . . . . . . . . .January 26, 2021 provided with acceptance notifications.)
• All poster presenters will be required to be
Abstract Submission Fees
available for a live Q&A session during an assigned
AAI Member $80 Nonmember $115 time. (Assigned times will be provided with
Abstract submission fees are non-refundable. Please note acceptance notifications.)
that registration fees are additional.
Please note: AAI cannot prevent screenshots of
posters or the photography/recording of poster
IMPORTANT presentations in a virtual environment.
For submission guidelines and details
TRAINEE
on abstract topic categories, visit
www.IMMUNOLOGY2021.org/abstracts.
ABSTRACT AWARDS
Hundreds of AAI members are eligible to receive
Trainee Abstract Awards each year! To be eligible for
these awards, individuals must be members of AAI
PUBLICATION OF ABSTRACTS at the time of abstract submission. Details about
Virtual IMMUNOLOGY2021™ awards can be found
All successfully presented abstracts at www.aai.org/Awards. Join AAI or renew your
will be published in a supplement to membership and submit your abstract by
January 26, 2021.
The Journal of Immunology.
To renew or become an AAI member, visit
www.aai.org/membership/join.
10 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORGVIRTUAL VIRTUAL
EXHIBIT HALL EXHIBITOR WORKSHOPS
Leading scientific companies and organizations will Take advantage of the knowledge-building opportunities
showcase their products and services. Attendees will presented in Virtual Exhibitor Workshops. These
be able to visit booths and learn more through product workshops explore the newest technologies, products,
videos and resources, engage through Live Chat and/or and services through presentations, demonstrations,
scheduled appointments, and attend workshops. and discussions.
Plan which exhibits you wish to visit and learn more by Workshops are planned and conducted by exhibitors.
viewing the interactive Virtual Exhibit Hall at These sessions do not constitute endorsement of any
www.IMMUNOLOGY2021.org/exhibitors. product or service by AAI.
Virtual Exhibit Hall Hours
Please note that all times listed are U.S. Eastern Time.
MEET THE EXHIBITORS ONLINE!
Tuesday, May 11
10:30 AM–8:00 PM Visit www.IMMUNOLOGY2021.org/exhibitors
(Unopposed) 7:00 PM–8:00 PM
to learn about all the exciting new
Wednesday, May 12 products and services you will see at
9:00 AM–6:30 PM Virtual IMMUNOLOGY2021™.
(Unopposed) 9:00 AM–10:00 AM
Thursday, May 13
JOBS BOARD
10:30 AM–8:00 PM
(Unopposed) 7:00 PM–8:00 PM
Friday, May 14 Post Online
9:00 AM–6:30 PM
(Unopposed) 9:00 AM–10:00 AM AAI offers career services to job seekers and employers
through the Jobs Board—free for registrants and exhibitors.
Saturday, May 15
10:30 AM–5:30 PM Jobs Board submission information will be available
(Unopposed) 1:00 PM–2:00 PM online in February 2021.
11 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORGREGISTRATION
Registration Now Open
Early Registration Deadline: April 20, 2021
The registration fee covers access to all scientific events, posters, exhibits, social events, and archived scientific
program. Visit www.IMMUNOLOGY2021.org/registration for complete details.
EARLY REGISTRATION REGULAR REGISTRATION
REGISTRATION CATEGORIES AND FEES
December 1–April 20 After April 20
Regular, Associate,
$395 $495
and Postdoc
Emeritus $250 $250
MEMBERS*
Young Professionals $150 $175
Graduate Student $80 $115
Undergrad Student $55 $75
egular, Associate,
R
$595 $695
NONMEMBERS* and Postdoc
Take advantage of Young Professionals $250** $450**
reduced rates by Graduate Student $225** $450**
becoming a member
Undergrad Student $225** $450**
or renewing before
registering. High School Teacher $55**
High School Student $55**
There is a special registration rate for scientists from developing countries. Please contact meetings@aai.org to register.
$75 up until No refunds after
Cancellation Fee
April 20, 2021 April 20, 2021
*Registrants must be a member at the time of IMPORTANT DATES
registration to qualify for the lowest rates. Registrants
AND DEADLINES
who renew or become members after registering for
the meeting will not be refunded the difference in
rates. Visit www.aai.org/membership to join or direct Abstract Submission
inquiries to members@aai.org. Abstract Submission Now Open
**Contact meetings@aai.org to register. Abstract Submission Closes January 26, 2021
Trainee Abstract Awards
JOIN US ONLINE MAY 10–15, 2021, Application cycle Now Open
FOR MORE SCIENCE, MORE Application deadline January 26, 2021
TIME, YOUR WAY! Registration
Registration Now Open
Visit www.IMMUNOLOGY2021.org Early Registration Discount Ends April 20, 2021
to view the full program.
12 • CALL FOR ABSTRACTS WWW.IMMUNOLOGY2021.ORGYou can also read
