Flu (Influenza) and Pneumonia Immunization Vaccines
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Flu (Influenza) and Pneumonia Immunization Vaccines Policy Number: PG0196 ADVANTAGE | ELITE | HMO Last Review: 10/01/2021 INDIVIDUAL MARKETPLACE | PROMEDICA MEDICARE PLAN | PPO GUIDELINES This policy does not certify benefits or authorization of benefits, which is designated by each individual policyholder terms, conditions, exclusions and limitations contract. It does not constitute a contract or guarantee regarding coverage or reimbursement/payment. Self-Insured group specific policy will supersede this general policy when group supplementary plan document or individual plan decision directs otherwise. Paramount applies coding edits to all medical claims through coding logic software to evaluate the accuracy and adherence to accepted national standards. This medical policy is solely for guiding medical necessity and explaining correct procedure reporting used to assist in making coverage decisions and administering benefits. SCOPE X Professional _ Facility DESCRIPTION The flu is a contagious respiratory illness caused by influenza viruses that infect the nose, throat, and lungs. It can cause mild to severe illness, and at times can lead to death. Vaccination to prevent influenza is particularly important for persons who are at increased risk for severe illness and complications from influenza and for influenza-related outpatient, emergency department, or hospital visits. The best way to prevent the flu is by getting a flu vaccine each year. Pneumonia vaccine is an infection of the lung, and can be caused by nearly any class of organism known to cause human infections, bacteria, viruses, fungi and parasites. Vaccines prevent disease in the people who receive them and protect those who are exposed to unvaccinated individuals. Immunization, also known as vaccination, is a means of triggering acquired immunity against certain infectious diseases. This is a specialized form of immunity that provides long-lasting protection against specific antigens, such as certain diseases. Small doses of an antigen (such as dead or weakened live viruses) are given to activate the body’s immune system. Persons who receive the vaccine will be immune only to those strains of the virus from which the vaccine was prepared. Vaccinations/immunizations are covered when recommended by the Centers for Disease Control and Prevention (CDC) and the American Academy of Pediatrics (AAP) and when US Food and Drug Administration (FDA) guidelines are met. The Advisory Committee on Immunization Practices (ACIP) of the Centers of Disease Control and Prevention (CDC) web site contains the most current information regarding the use of vaccines and immunizations in the United States, including both recommendations/schedules and precautions. ACIP Recommendations: http://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/index.html POLICY Flu and Pneumonia Immunization Vaccines do not require prior authorization. Vaccination Products Pending FDA Approval are non-covered, including but not limited to 90666, 90667, & 90668. PG0196 – 10/01/2021
Code 90664 (pandemic vaccine) is non-covered for HMO, PPO, Individual Marketplace, & Elite/ProMedica Medicare Plan. HMO, PPO, Individual Marketplace members must receive the vaccine from participating providers. Advantage and Elite/ProMedica Medicare Plan members may receive their vaccines from a non- participating provider. COVERAGE CRITERIA HMO, PPO, Individual Marketplace, Elite/ProMedica Medicare Plan, Advantage Paramount covers certain services under the Preventive Care Services benefit. The standard influenza and pneumococcal vaccines are provided to all members without a co-pay. Paramount members may receive influenza and pneumococcal vaccines from any provider that participates with Paramount and who provides influenza and pneumococcal vaccines as covered in full. Covered Flu & Pneumonia Codes by Product Line The following codes are covered without a copay when: PRODUCT Provided as the ONLY service or with only a preventive service. Administered in the office of a participating PCP or Specialist, or at a participating pharmacy location. 90460, 90461, 90471, 90472, 90473, 90474, 90630, 90653, HMO, PPO, Individual 90654, 90655, 90656, 90657, 90658, 90660, 90661, 90662, Marketplace 90670, 90672, 90673, 90674, 90677, 90682, 90685, 90686, 90687, 90688, 90689, 90694, 90732, 90756 G0008, G0009, Q2034, Q2035, Q2036, Q2037, Q2038, Q2039, 90460, 90461, 90473, 90474, 90630, 90653, 90654, 90655, 90656, 90657, 90658, 90660, 90661, 90662, 90670, 90671, 90672, 90673, 90674, 90677, 90682, 90685, 90686, 90687, 90688, 90689, 90694, 90732, 90756 90460, 90471, 90472, 90473, 90474, 90630, 90653, 90654, 90656, 90658, 90660, 90662, 90670, 90672, 90673, 90674, 90682, 90685, 90686, 90687, 90688, 90694, 90732, 90756, Q2034, Q2035, Q2039 (Advantage administration codes are listed for billing/reporting purposes only and do not imply payment.) Routine immunizations with a U.S. Food and Drug Administration (FDA) licensed vaccine are covered as medically necessary when used in accordance with a recommendation by the Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP). Coverage criteria are adjusted when national guidelines are revised to address new vaccines or changes in PG0196 – 10/01/2021
vaccine indications, or when the CDC makes recommendations for changes in administration schedules related to national vaccine shortages. Influenza and Pneumonia Immunizations are a covered preventive benefit, both for adults and for children Influenza Vaccination Standard or preservative-free trivalent or quadrivalent injectable influenza vaccines are considered medically necessary according to the recommendations of the Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP). Routine annual influenza vaccination is recommended for all persons aged 6 months and older who do not have contraindications. Routine annual influenza vaccination is recommended for health care personnel, caregivers and persons who live with those who are at increased risk for medical complications attributed to severe influenza. Vaccination to prevent influenza is particularly important for persons who are at increased risk for severe illness and complications from influenza and for influenza-related outpatient, emergency department, or hospital visits. o All children aged 6 through 59 months; o All persons aged 50 years and older; o Adults and children who have chronic pulmonary (including asthma), cardiovascular (excluding isolated hypertension), renal, hepatic, neurologic, hematologic, or metabolic disorders (including diabetes mellitus); o Persons who are immunocompromised due to any cause (including but not limited to immunosuppression caused by medications or HIV infection); o Women who are or will be pregnant during the influenza season; o Children and adolescents (aged 6 months through 18 years) who are receiving aspirin- or salicylate- containing medications and who might be at risk for experiencing Reye syndrome after influenza virus infection; o Residents of nursing homes and other long-term care facilities; o American Indians/Alaska Natives; and o Persons who are extremely obese (body mass index ≥40 for adults). 90660 and 90672 (Intranasal flu vaccinations) are covered for aged 2 through 49 years of age if a flu shot is not the preferred option. 90662, high dose flu vaccine (Fluzone) is covered for members 65 and over only. Pneumococcal Vaccination Pneumococcal vaccines are considered medically necessary according to the recommendations of the Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP). 13-valent pneumococcal conjugate vaccine (PCV13, Prevnar13®) 23-valent pneumococcal polysaccharide vaccine (PPSV23, Pneumovax®23) 13-valent pneumococcal polysaccharide-protein conjugate vaccine (PCV13) or 23-valent pneumococcal polysaccharide vaccine (PPSV23) is considered medically necessary and, therefore, covered for the following individuals: Children Routine childhood PCV13 vaccination at ages 2 months, 4 months, 6 months, and 12 months through 15 months. The first dose of PCV13 is covered as early as 6 weeks of age. Catch-up PCV13 vaccination for under-vaccinated healthy children up to 5 years of age at subsequent visits. Adults PG0196 – 10/01/2021
Standard 23-valent pneumococcal polysaccharide vaccine (PPV23, e.g., Pneumovax, Pnu-immune) is considered medically necessary for all individuals aged 65 years or older. Vaccination considered covered for members with high-risk conditions with PCV13 and PPSV23: Children o For children 2 years through 18 years of age with any of the following conditions: chronic heart disease (particularly cyanotic congenital heart disease and cardiac failure); chronic lung disease (including asthma if treated with high-dose corticosteroid therapy); diabetes mellitus; cerebrospinal fluid leak; cochlear implant; sickle cell disease and other hemoglobinopathies; anatomic or functional asplenia; HIV infection; chronic renal failure; nephrotic syndrome; diseases associated with immunosuppressive drugs or radiation therapy, including malignant neoplasms, leukemias, lymphomas, and Hodgkin disease; solid organ transplantation; acquired or congenital immunodeficiency; multiple myeloma. o For children aged 6 through 18 years with alcoholism or chronic liver disease. Adults o Adults aged 19 or older with immunocompromising conditions, (e.g., congenital or acquired immunodeficiency disorders [including B- and T-lymphocyte deficiency, complement deficiencies, phagocytic disorders], HIV infection, anatomical or functional asplenia [including sickle cell disease and other hemoglobinopathies], chronic renal failure, leukemia, lymphoma, Hodgkin disease, generalized malignancy, iatrogenic immunosuppression [e.g. drug or radiation therapy], solid organ transplant, multiple myeloma, and nephrotic syndrome), cerebrospinal fluid leak, or cochlear implant. o Adults aged 19 years through 64 years with chronic medical conditions (e.g. chronic heart disease (excluding hypertension), chronic lung disease, chronic liver disease, diabetes mellitus), alcoholism, or who smokes cigarettes. PCV13 and PPSV23, when indicated, will be covered for members whose pneumococcal vaccination history is incomplete or unknown. Adults 65 years or older who have not previously received the PCV13 vaccine when indicated by shared clinical decision-making. If PPSV23 was administered prior to age 65 years, adults 65 years or older for a routine dose of PPSV23 at least 5 years after the previous PPSV23 dose. After heptavalent pneumococcal conjugate vaccine (PCV7) in Alaska Native or American Indian children aged 24 through 59 months who are living in areas where the risk of invasive pneumococcal disease is increased. Alaska Native and American Indian persons aged 50 to 64 years who are living in areas where the risk of invasive pneumococcal disease is increased, when recommended by public health authorities Routine re-vaccination is not recommended by the CDC for pneumococcal vaccines. In accordance with the CDC’s recommendations, re-vaccination is considered medically necessary only for the following groups: Persons aged 65 years or older if they received vaccine 5 or more years previously and was less than 65 years of age at the time of vaccination; Persons aged 2 to 64 years with the following conditions in which the second dose of PPSV23 is given at least 5 years after the first dose of PPSV23: o Anatomic or functional asplenia; o Chronic renal failure or nephrotic syndrome; o Congenital or acquired immunodeficiency (including HIV infection); o Generalized and metastatic malignancies; o Hodgkin disease; o Iatrogenic immunosuppression, including radiation therapy; PG0196 – 10/01/2021
o Leukemia or lymphoma; o Multiple myeloma; o Sickle cell disease or other hemoglobinopathies; o Solid organ transplant; o Sickle cell disease or other hemoglobinopathies. In addition, re-vaccination with the 23-valent pneumococcal polysaccharide vaccine is considered medically necessary for high-risk individuals who received the 14-valent polysaccharide vaccine, which was in use prior to 1983. Pneumococcal 13-valent Conjugate Vaccine (PCV13, Prevnar 13) Note: In 2010, heptavalent pneumococcal conjugate vaccine (PCV7, e.g., Prevnar, Prevenar) was replaced by PCV13 (e.g., Prevnar 13). The use of 13-valent pneumococcal conjugate vaccine (PCV 13; Prevnar 13 is considered in series with PPSV23 (e.g. Pneumovax) medically necessary for adults aged 19 years or older (including those aged 65 years and older) with immunocompromising conditions, CSF leaks, or cochlear implants. The use of a dose of PCV13 (e.g., Prevnar 13) is considered followed by a dose of PPSV23 (e.g., Pneumovax) medically necessary for adults aged 65 years and older who want to receive PCV13 and do not have an immunocompromising condition, cerebrospinal fluid leak, or cochlear implant and have not previously received PCV13. Note: if member already received PPSV23, a dose of PCV13 may be given at least one year after they received the most recent dose. Pneumococcal 13-valent conjugate vaccine (PCV13) is considered experimental and investigational for other groups because its effectiveness for groups other than the ones listed above has not been established. CDC recommends some adults receive up to 3 doses of PPSV23 in a lifetime. Adults who have functional or anatomic asplenia or immunocompromising conditions should receive two doses of PPSV23, given 5 years apart, before age 65 years. Those adults should then receive a third dose of PPSV23 at or after 65 years, as long as it has been at least 5 years since the most recent dose. CDC recommends all adults receive 1 dose of PCV13, if indicated and if they have not received PCV13 previously (including childhood series). For most people, this will be as part of the routine recommendation to administer PCV13 to all adults 65 years of age or older. However, if an adult received a dose of PCV13 prior to turning 65 years of age (due to a medical indication), they do not also need to receive a dose of PCV13 when they turn 65. Note Codes may not be all inclusive as the American Medical Association (AMA) and Centers for Medicare and Medicaid Services (CMS) code updates and FDA approvals may occur more frequently than policy updates. Vaccines and immunizations for the sole purpose of travel outside of the continental United States are not covered. Paramount does not reimburse for vaccines that are available free from the state. Paramount does not reimburse for vaccines that are not FDA-approved Definitions Immunity – is protection from an infectious disease Immunization – is an inoculation against a vaccine preventable disease Vaccination – the act of introducing a vaccine into the body to produce immunity to a specific disease PG0196 – 10/01/2021
Vaccine – a preparation of a weakened or dead pathogen that stimulates a person’s immune system to produce immunity to a specific disease, protecting the person from that disease. Vaccines are usually administered through needle injections, but can also be administered by mouth or sprayed into the nose CODING/BILLING INFORMATION The inclusion or exclusion of a code in this section does not necessarily indicate coverage. Codes referenced in this clinical policy are for informational purposes only. Codes that are covered may have selection criteria that must be met. Payment for supplies may be included in payment for other services rendered. CPT CODES BRAND NAME 90460 Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; first or only component of each vaccine or toxoid administered 90461 Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional; each additional vaccine or toxoid administered (List separately in addition to code for primary procedure.) 90471 Immunization administration, one vaccine 90472 Immunization administration, each additional vaccine 90473 Immunization administration by intranasal or oral route; one vaccine 90474 Immunization administration by intranasal or oral route; each additional vaccine 90630 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, Fluzone Quad Intradermal for intradermal use 90653 Influenza virus vaccine, inactivated (IIV), subunit, adjuvant, for Fluad intramuscular use 90654 Influenza virus vaccine, split virus, preservative free, for intradermal use Fluzone 90655 Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.25 Afluria mL dosage, for intramuscular use 90656 Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 Afluria, Fluvirin, Fluarix mL dosage, for intramuscular use 90657 Influenza virus vaccine, trivalent (IIV3), split virus, 0.25 mL dosage, for Afluria, Flulaval, Fluvirin intramuscular use 90658 Influenza virus vaccine, trivalent (IIV3), split virus, 0.5 mL dosage, for Afluria, FluLaval, Fluvirin intramuscular use 90660 Influenza virus vaccine, trivalent, live, for intranasal use FluMist 90661 Influenza virus vaccine trivalent (ccIIV3), derived from cell cultures, Flucelvax subunit, preservative and antibiotic free, 0.5 mL dosage, for intramuscular use 90662 Influenza virus vaccine (IIV), split virus, preservative free, enhanced Fluzone High-Dose immunogenicity via increased antigen content, for intramuscular 90664 Influenza virus vaccine, live (LAIV), pandemic formulation, for intranasal Novel influenza – H1N1-09 use nasal 90670 Pneumococcal conjugate vaccine, 13 valent (PCV13), for intramuscular Prevnar 13 use 90671 Pneumococcal conjugate vaccine, 15 valent (PCV15), for intramuscular Vaxneuvance use (Effective 7/1/2021) 90672 Influenza virus vaccine, quadrivalent, live (LAIV4), for intranasal use FluMist 90673 Influenza virus vaccine, trivalent, derived from recombinant DNA (RIV3), Flublok hemagglutin (HA) protein only, preservative and antibiotic free, for intramuscular use 90674 Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, Flucelvax subunit, preservative and antibiotic free, 0.5 mL dosage, for PG0196 – 10/01/2021
intramuscular use (Effective 07/01/2016) 90677 Pneumococcal conjugate vaccine, 20 valent (PCV20), for intramuscular Prevnar 20 use (Effective 7/1/2021) 90682 Influenza virus vaccine, quadrivalent (RIV4), derived from recombinant Flublok DNA, hemagglutinin (HA) protein only, preservative and antibiotic free, for intramuscular use 90685 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, Fluzone 0.25 mL dosage, for intramuscular use 90686 Influenza virus vaccine, quadrivalent (IIV4), split virus, preservative free, Afluria, Fluarix, Fluzone, 0.5 mL dosage, for intramuscular use Flulaval 90687 Influenza virus vaccine, quadrivalent (IIV4), split virus, 0.25 mL dosage, Fluzone for intramuscular use 90688 Influenza virus vaccine, quadrivalent (IIV4), split virus, 0.5 mL dosage, Afluria, FluLaval, Fluzone for intramuscular use 90689 Influenza virus vaccine quadrivalent (IIV4), inactivated, adjuvanted, preservative free, 0.25 mL dosage, for intramuscular use (Effective 01/01/19) 90694 Influenza virus vaccine, quadrivalent (aIIV4), inactivated, adjuvanted, Fluad Quadrivalent preservative free, 0.5 mL dosage, for intramuscular use 90732 Pneumococcal polysaccharide vaccine, 23-valent (PPSV23), adult or Pneumovax 23 immunosuppressed patient dosage, when administered to individuals 2 years or older, for subcutaneous or intramuscular use 90756 Influenza virus vaccine, quadrivalent (ccIIV4), derived from cell cultures, Flucelvax subunit, antibiotic free, 0.5mL dosage, for intramuscular use HCPCS CODES G0008 Administration of influenza virus vaccine G0009 Administration of pneumococcal vaccine Q2034 Influenza virus vaccine, split virus, for intramuscular use (Agriflu) Agriflu Q2035 Influenza virus vaccine, split virus, when administered to individual 3 Afluria years of age and older, for intramuscular use (Afluria) Q2036 Influenza virus vaccine, split virus, when administered to individuals 3 Flulaval years of age and older, for intramuscular use (Flulaval) Q2037 Influenza virus vaccine, split virus, when administered to individuals 3 Fluvirin years of age and older, for intramuscular use (Fluvirin) Q2038 Influenza virus vaccine, split virus, when administered to individuals 3 Fluzone years of age and older, for intramuscular use (Fluzone) Q2039 Influenza virus vaccine, split virus, when administered to individuals 3 years of age and older, for intramuscular use (not otherwise specified) Vaccination Products Pending FDA Approval - Non-Reimbursable CPT Codes 90666 Influenza virus vaccine (IIV), pandemic formulation, split virus, preservative free, for intramuscular use 90667 Influenza virus vaccine (IIV), pandemic formulation, split virus, adjuvant, for intramuscular use 90668 Influenza virus vaccine (IIV), pandemic formulation, split virus, for intramuscular use Paramount reserves the right to review and revise our policies periodically when necessary. When there is an update, we will publish the most current policy to https://www.paramounthealthcare.com/services/providers/medical-policies/ . REVISION HISTORY EXPLANATION PG0196 – 10/01/2021
ORIGINAL EFFECTIVE DATE: 01/15/2009 Date Explanation & Changes 09/01/09 Updated to include H1N1 vaccine 07/01/10 New vaccines 01/01/11 New codes 01/01/12 Procedure code 90663 was deleted. Procedure code 90654 was added 01/01/13 Procedure codes 90672, 90685, 90686, 90687, 90688, Q2034 were added Procedure code 90686 received FDA approval 12/12. Removed from Exception. 06/13/13 Medical Policy Reimbursement Committee reviewed 6/13 Added procedure codes 90673 & Q2033 as FDA approved 1/16/13. (Note procedure code 90661 FDA approved 11/12) 08/07/13 Separated codes in the FDA pending state, 90653, 90666, 90667, 90668, 90687, 90688 Policy reviewed and updated to reflect most current clinical evidence Added Advantage vaccine administration denial 10/08/13 Approved by Medical Policy Steering Committee as revised 03/26/15 Codes 90687 & 90688 now FDA approved Added codes G0008 & G0009 Added effective 1/1/15 new FDA approved code 90630 as covered 07/14/15 Removed effective 12/31/13 deleted code Q2033 Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee Per the Medicare Tactical Team’s review and determination, procedures G0008 and G0009 03/25/16 are now non-covered for HMO and PPO and procedures 90471 and 90472 are now non- covered for Elite Code 90460 is covered for Advantage now per ODM Appendix DD 05/10/16 Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee Added effective 7/1/16 new code 90674 as covered for all product lines per administrative 10/13/16 direction Updated effective 1/1/17 revised codes 90655-90658, 90661, 90685-90688 Added effective 1/1/17 new code 90682 as pending FDA approval non-covered 11/08/16 Code 90653 now FDA approved and covered for all product lines Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee Code 90682 is now FDA approved and covered for all product lines Added effective 01/01/18 new code 90756 as covered for all product lines 01/09/18 Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee Fluzone high-dose (90662) vaccine is now covered for Advantage effective 11/01/2018 per ODM guidelines Added effective 01/01/19 new code 90689 as covered for all product lines Code 90664 (pandemic vaccine) is non-covered for HMO, PPO, Individual Marketplace, & 11/13/18: Elite Removed effective 12/31/15 deleted code 90669 Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee New code 90689 effective 01/01/19 is non-covered for Advantage per ODM guidelines 01/08/19 Policy reviewed and updated to reflect most current clinical evidence per Medical Policy Steering Committee Added procedure code 90694 to the medical policy coverage Elite and Commercial product 8/4/2020 lines Note: procedure 90694 is listed on the medical policy PG0137 Preventive Services 12/16/2020 Medical policy placed on the new Paramount Medical Policy Format PG0196 – 10/01/2021
Added procedures 90662 (10/01/2020), 90694 (01/01/2021), Q2034 (07/01/2012), Q2035 (01/01/2020), Q2039 (08/01/2017) to the Advantage coverage per ODM List of vaccines, toxoids, and other provider-administered injectable pharmaceuticals provided as practitioner services and referenced in rule 5160-4-12, revised 3/18/2021 05/04/2021 Deleted procedures 90655 (04/01/2007), 90657 (07/01/2008), 90664 (01/01/2011), to the Advantage coverage per ODM List of vaccines, toxoids, and other provider-administered injectable pharmaceuticals provided as practitioner services and referenced in rule 5160-4- 12, revised 3/18/2021 Added procedure 90658 to the Elite coverage - covered as a Part B benefit Policy reviewed and updated to reflect most current clinical evidence per Industry Standards 10/01/2021 Added procedure codes 90671 and 90677 to the Elite/ProMedica Medicare Plan and HMO, PPO, Individual Marketplace product lines, effective 7/1/2021 REFERENCES/RESOURCES Centers for Medicare and Medicaid Services, CMS Manual System and other CMS publications and services Ohio Department of Medicaid American Medical Association, Current Procedural Terminology (CPT®) and associated publications and services Centers for Medicare and Medicaid Services, Healthcare Common Procedure Coding System, HCPCS Release and Code Sets U.S. Preventive Services Task Force, http://www.uspreventiveservicestaskforce.org/ Industry Standard Review Hayes, Inc. Industry Standard Review CDC http://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/index.html PG0196 – 10/01/2021
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