Advanced International Breast Cancer Course - 14th MEET THE PROFESSOR PADUA, SEPTEMBER 20th-22nd, 2018 - Istituto Oncologico ...
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SECTION OF ONCOLOGY 14th MEET THE PROFESSOR Advanced International Breast Cancer Course PADUA, SEPTEMBER 20th-22nd, 2018 Directors Pier Franco Conte, Gabriel N. Hortobagyi
Aims Breast cancer represents the front runner in cancer research in many aspects. First, this is a common, chronic and lethal disease where medical interventions are successfully inducing a continuous decline in mortality in spite of increasing incidence. Second, biology drives the entire diagnostic-therapeutic work up of these patients. For these reasons, nowadays, a breast multidisciplinary team should also include pathologists, molecular biologists, oncogeneticists besides the “classic” clinical specialties. Finally, many highly effective interventions are available for each step of the diagnostic and therapeutic work-up of these patients. The increased complexity of the disease, the availability of multiple effective choices and the high expectations of our patients are raising the bar of clinical excellence in this field. With this goal in mind, the Programme of this international Conference includes lectures on molecular characterization, updated treatments of early and advanced disease, management of difficult cases and hereditary syndromes. Clinical case discussions and debates are planned to allow a continuous and fruitful exchange of experiences and opinions between speakers and participants. This 14th Breast Cancer Conference includes a highly qualified international faculty, but will maintain its characteristics of a friendly forum where opinion leaders and attendees will exchange experiences and share the most exiting advances. In order to reward scientific excellence and to foster international cooperation, the International Scientific Committee of the 14th AIBCC will award the 8th International Prize for Breast Cancer Research to a scientist who has published a breakthrough paper in the previous year. For the first time, we also welcome the presentation of posters from the participants and the best poster will be awarded during the Award Cerimomy. We welcome medical oncologists, pathologists, breast surgeons, radiation oncologists and basic scientists to listen to breast cancer leaders and to exchange experiences in a friendly atmosphere. Addressed to Gynaecologists and obstetrics, medical oncologists, pathologists, radiologists, radiation oncologists, surgeons. Biologists and nurses. Pharmacists. It won’t be possible to give credits to physicians specialized in different fields.
Programme
Thursday, September 20th
8.30 Registration
9.15 Introduction to the Conference
Pier Franco Conte, Gabriel N. Hortobagyi
SESSION I - EVOLUTION IN BREAST CANCER PREVENTION
Chairmen: Francesca Caumo, Stefania Zovato
9.30 Population screening vs risk-adapted surveillance
Sylvia Heywang – Kobrunner
9.50 harmacological prevention: how and whom?
P
Elefterios Mamounas
A look
10.10 into the future: multigene panels
Gabriel N. Hortobagyi
10.30 Q&A
10.45 Coffee break
ESSION II - LOCOREGIONAL TREATMENT
S
Chairmen: Jacek Jassem, Gabriel N. Hortobagyi
11.15 volution in surgical management of the axilla
E
Viviana E. Galimberti
11.45 o margins still matter for in situ and invasive lesions?
D
Elefterios Mamounas
12.15 adiation therapy: what is the real target to aim at
R
Philip Poortmans
12.45 Q&A
13.00 Lunch
ultidisciplinary Tumor Board 1 – Locoregional treatment
M
14.00
Chairman: Jacek Jassem
Panelists: Maia Dzhugashvili, Hesham Elghazaly,
Viviana E. Galimberti, Philip Poortmans
Case 1: Locoregional relapse (questions: locoregional treatment with
or without radiosensitisers e.g drugs, hyperthermia, EF? “Adjuvant”
systemic treatment?) – Laura Martella
Case 2: Breast cancer in a patient previously treated with RT for
Hodgkin disease (questions: locoregional treatment? contralateral
mastectomy?) – Tania Saibene
Case 3: Healthy patient with familial history asking for risk-reducing
mastectomy – Silvia Michieletto
Concluding comments – Jacek Jassem
SESSION III – SUPPORTIVE AND COMPLEMENTARY THERAPIES
Chairmen: Pier Franco Conte, Stefania Migliuolo
15.00 iet: myths and facts
D
Mariateresa Nardi
15.20 Complementary therapies
Claudia Bozza
15.40 Scalp cooling
Laura Marchioro
16.00 Q&A
16.20 Coffee break
SESSION IV – LONG TERM CONSEQUENCES OF SYSTEMIC TREATMENTS
Chairmen: Hesham Elghazaly, Valentina Guarneri
16.40 Gynecologic
Marco Gambacciani
17.00 ardiovascular and metabolic
C
Giuseppe Curigliano
17.20 Bone health
Ingo Diel
17.40 Q&A
18.00 AdjournFriday, September 21st
8.00 Poster display
SESSION V – PATHOLOGY, GENOMICS & MOLECULAR BIOLOGY
Chairman: Enrico Orvieto
9.00 ER2 testing guidelines: new ASCO/CAP 2018
H
Giuseppe Viale
9.20 olecular stratification of HER2+ and TNBC
M
Aleix Prat
9.40 L obular breast cancer: a separate entity?
Caterina Marchiò
10.00 Q&A
10.20 Coffee Break
SESSION VI – NEW PATHWAYS AND NEW DRUGS
Chairmen: Sybille Loibl, Aleix Prat
10.50 Insights in resistance to CDK4/6 inhibitors
Stephen Johnston
11.10 Targeting the immune system: hopes and hypes
Peter Schmid
11.30 ombining radiotherapy and immunotherapy
C
Emanuela Romano
11.50 ARPi and other promising agents
P
Gabriel N. Hortobagyi
12.10 Q&A
12.30 LunchSESSION VII – SYSTEMIC TREATMENTS FOR EARLY BREAST CANCER
Chairmen: Stephen Johnston, Gabriel N. Hortobagyi
14.00 xtended adjuvant endocrine therapy: why? for whom? with what?
E
Michael Gnant
14.30 isk adapted adjuvant treatment for HER2+ disease
R
Pier Franco Conte
15.00 ost promising ongoing trials in early disease
M
Hope Rugo
15.30 Q&A
ultidisciplinary Tumor Board 2 – Early breast cancer:
M
16.00
challenging cases for pathologists and clinicians
Chairman: Giuseppe Viale
Panelists: Giulia Valeria Bianchi, Maria Vittoria Dieci, Miguel Martin,
Hope Rugo
Case 1: Rare histologies (pleomorphic lobular carcinoma, low aggressive
triple negative histologies, micropapillary) – Vassilena Tsvetkova
Case 2: HER2+ (de-escalated treatments for HER2+ disease)
Giulia Tasca
Case 3: Management of non pCR after neoadjuvant chemotherapy
Carlo Alberto Giorgi
Concluding comments - Maria Vittoria Dieci
17.00 Adjourn
17.30 Ceremony for the presentation of the University of Padua Award
for Advances in Breast Cancer 2018 and best poster award
17.45 Lecture of the Awardee
18.15 Cocktail
19.30 Adjourn
he Ceremony and the cocktail will take place in Palazzo Bo,
T
Via VIII Febbraio 2, PaduaSaturday, September 22nd
SESSION VIII – Advanced Breast Cancer
Chairmen: Pier Franco Conte, Stephen Johnston
9.00 ew therapeutic algorithms
N
HR+ disease - Sibylle Loibl
HER2+ disease - Valentina Guarneri
TN disease - Miguel Martin
10.30 Q&A
10.40 Coffee break
11.00 Do elderly patients require special management?
Matti Aapro
ultidisciplinary Tumor Board 3 – Management of Advanced
M
11.20
Breast Cancer
Chairman: Sandra Swain
Panelists: Giulia Valeria Bianchi, Jacek Jassem, Philip Poortmans,
Hope Rugo
Case 1: Bone disease – Zora Baretta
Case 2: Brain mets – Gaia Griguolo
Case 3: Fulminat visceral disease – Luisa Carbognin
Case 4: Oligometastatic disease – Giacomo Pelizzari
Concluding comments – Sandra Swain
12.45 Adjourn and final evaluation questionnaireDirectors
Pier Franco Conte Gabriel N. Hortobagyi
Division of Medical Oncology 2 Department of Breast Medical Oncology
Istituto Oncologico Veneto IRCCS The University of Texas
Department of Surgery, Oncology MD Anderson Cancer Center
and Gastroenterology Houston (USA)
University of Padua (I)
Scientific Committee
Hesham Elghazaly Miguel Martin
Department of Clinical Oncology and nuclear Medical Oncology Service
medicine Hospital Universitario Gregorio Marañon
University of Ainshams Madrid (E)
Cairo (EG)
Stefania Migliuolo
Valentina Guarneri Europa Donna Italia
Division of Medical Oncology 2 Milan (I)
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology Fedro Alessandro Peccatori
and Gastroenterology Department of Medical Oncology
University of Padua (I) European Institute of Oncology (IEO)
Milan (I)
Jacek Jassem
Department of Oncology and Radiotherapy Philip Poortmans
Medical University of Gdansk (PL) President of ECCO
Department of Radiation Oncology
Stephen Johnston Institut Curie
NIHR Biomedical Research Centre for Cancer Paris (F)
Royal Marsden NHS Foundation
Trust & Institute of Cancer Research Aleix Prat
London (UK) Medical Oncology Department
Hospital Clinic
Sibylle Loibl Barcellona (E)
German Breast Group
Department of Medicine and Research
University of Frankfurt (D)Speakers & Chairmen
Matti S. Aapro Viviana E. Galimberti
Multidisciplinary Oncology Institute Unit of Molecular Senology
Clinique De Genolier European Institute of Oncology
Genolier (CH) Milan (I)
Zora Baretta Marco Gambacciani
Medical Oncology Unit AULS 8 Obstetrics & Gynecology Unit
Berica Distretto Ovest S. Chiara Hospital
Arzignano (I) Pisa (I)
Giulia Valeria Bianchi Carlo Alberto Giorgi
Medical Oncology Unit 1 Division of Medical Oncology 2
IRCCS Istituto Nazionale Tumori Istituto Oncologico Veneto IRCCS
Milan (I) Department of Surgery, Oncology and
Gastroenterology
Claudia Bozza University of Padua (I)
Department of Oncology
ASUIUD Michael Gnant
Udine Department of Surgery
Medical University
Luisa Carbognin Wien (A)
Medical Oncology Unit
G.B. Rossi Hospital Gaia Griguolo
Verona (I) Division of Medical Oncology 2
Istituto Oncologico Veneto IRCCS
Francesca Caumo Department of Surgery, Oncology and
Radiology Unit Gastroenterology
Istituto Oncologico Veneto IRCCS University of Padua (I)
University of Padua (I)
Sylvia H. Heywang-Köbrunner
Giuseppe Curigliano Head of Breast Diagnostics
Department of Oncology Munchen (D)
European Institute of Oncology
University of Milan (I) Eleuterios Mamounas
MD Anderson Cancer Center Orlando
Maria Vittoria Dieci Comprehensive Breast Program
Division of Medical Oncology 2 Orlando (F)
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and Caterina Marchiò
Gastroenterology Pathology Unit
University of Padua (I) Candiolo Cancer Institute IRCCS
Candiolo (I)
Ingo Diel
Gynaecology Unit Laura Marchioro
Praxisklinik am Rosengarten Division of Medical Oncology 2
Mannheim (D) Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and
Maia Dzhugashvili Gastroenterology
Department of Radiation Oncology University of Padua (I)
Instituto Madrileño de Oncología (Grupo IMO)
Murcia (E)Laura Martella Sandra Swain M.
Medical Oncology Research Development
“S. Anna” Hospital Georgetown University Medical Center
Cona, Ferrara (I) Washington (USA)
Silvia Michieletto Giulia Tasca
Breast Surgery Division of Medical Oncology 2
Istituto Oncologico Veneto IRCCS Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and Department of Surgery, Oncology and
Gastroenterology Gastroenterology
University of Padua (I) University of Padua (I)
Mariateresa Nardi VassilenaTsvetkova
Clinical nutrition and dietetics Division of Medical Oncology 2
Istituto Oncologico Veneto Istituto Oncologico Veneto IRCCS
Padova (I) Department of Surgery, Oncology and
Gastroenterology
Enrico Orvieto University of Padua (I)
General Pathology and Cytopatology Unit
Department of Medicine-DIMED Giuseppe Viale
University of Padua (I) Department of Pathology
European Institute of Oncology
Giacomo Pelizzari University of Milan (I)
Medical Oncology
Oncology Center Stefania Zovato
Aviano (I) Familial Cancer Clinic (Unità tumori ereditari)
Istituto Oncologico Veneto IRCCS
Emanuela Romano Department of Surgery, Oncology and
Cancer Immunotherapy Center Gastroenterology
Institut Curie Padova
Paris (F)
Hope Rugo
UCSF Carol Franc Buck Breast Care Center
Breast Oncology Clinical Trials Program
San Francisco (USA)
Tania Saibene
Breast Surgery
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and
Gastroenterology
University of Padua (I)
Peter Schmid
Centre for Experimental Cancer Medicine Bart
Cancer
Institute Queen Mary University
London (UK)Award, Poster Session & Fellowships UNIVERSITY OF PADUA AWARD FOR ADVANCES IN BREAST CANCER 2018 The Scientific Committee will select young researchers (< 40 years from any country) who have published in an international peer-reviewed journal, as the principal author, a manuscript reporting important clinical or biological advances in breast cancer. Prof. Conte and Prof. Hortobagyi will select the final winner which will be invited to present his/her study during the annual Conference. POSTER SESSION Participants can send one or more abstracts. The form (available on the web site: https://meettheprofessor.accmed.org) should be filled out by following specific guidelines: • Use the capitol letter for the title • Indicate each author’s affiliation (that should include institution, department and town) • Underline the designated presenting author’s name. • Use font Times New Roman 10, single line spacing. Abstracts will be selected by the Scientific Committee and will be shown during the poster session on September 22nd from 8 am. Poster size: 70 (wide) x 100 (high). People sending the selected abstracts will have free registration, dinners and accommodation as well as a reimbursement of travel expenses (max of travel reimbursement € 200,00 for Italian participants and € 300,00 for European and worldwide participants). Abstracts should be sent within July 1st. A confirmation will be sent by email within July 20th. FELLOWSHIPS Some fellowship (for under 40) will be awarded which will include registration and 3 Hotel nights. Those interested should send the registration form together with a short CV and a motivation letter within July 1st. The organizing secretariat will confirm the award of the fellowship within July 20th and it will proceed with the organization of logistics.
Under 35
Free admission is available for 3 people “under 35”. Registration forms will be
accepted on a first-come, first-served basis until spaces will be full.
The Organization Secretariat will confirm the registration by email.
Un’azione sostenibile a favore della formazione
Iscrizione gratuita per i medici UNDER 35 fino a esaurimento posti
CME
Based on Italian regulations, Accademia Nazionale di Medicina (provider n. 31)
will assign to the activity CME (31-228175): 11,2 CME points.
The credit certification is subject to:
• Professions/specializations should correspond to those which have been
accredited for CME;
• 90% attendance to the meeting;
• Completion of the meeting evaluation form;
• Completion of the final questionnarie (at least 75% of correct answers).
We would like to remind you to participants that only 1/3 of CME credits acquired
during the years 2017/2019 can come from a sponsorship.
Official Language
The official language of the Meeting is English. No simultaneous translation will
be provided.Registration The registration fee are: - € 250,00 - € 150,00 for graduate students - € 150,00 for nurses They include the conference bag and all coffee breaks and lunches. They do not include Hotel accomodation, dinners and travel expenses. To register, please send: • registration form duly filled out (even when sponsored by a Pharmaceutical Company) • privacy statement and consent to the use of personal data (as in the back of the form) • payment to Accademia Nazionale di Medicina - Galleria Ugo Bassi 2, 40121 Bologna (fax 0039 51 0569162 – e.mail: info.bologna@accmed.org), within August 25th, 2018. Online registration is possible on the website http://meettheprofessor.accmed.org. By submitting the form and the payment, your registration is completed with the exception of specific decisions of the Meeting Secretariat. Incomplete registration will NOT be admitted. The registration will be confirmed by e-mail, please put your e-mail address on the registration form. CANCELLATION • If the participants minimum number is not reached, Accademia Nazionale di Medicina will advise by a written communication and proceed with the total refund of the fee. • In order to cancel please give advise with a written communication to Accademia Nazionale di Medicina within 10 days from the beginning. A 70% of the registration fee will be returned. Any cancellation after that deadline will not be reimbursed. Meeting Venue Centro Congressi Papa Luciani Via Forcellini 170/A Padua How to reach the meeting venue: Radio taxi: 049 651333 The Congress Centre Papa Luciani has a large and free parking.
With the patronage of
INSTITUTIONS
Comune di Padova
SCIENTIFIC SOCIETIESWith the unconditional contribution of SILVER SPONSOR BRONZE SPONSOR CONTRIBUTORS › AMGEN › CLOVIS ONCOLOGY IT › GENOMIC HEALTH INTERNATIONAL › IPSEN › TAKEDA
Sponsored by
ACCADEMIA NAZIONALE
DI MEDICINA
www.accmed.org
General Manager: Stefania Ledda
Organizing Partner
Forum Service
Via Martin Piaggio 17/6
16122 Genova
Information:
http://meettheprofessor.accmed.org
Ph. +3951 0569163 – 6360080
Fax +3951 0569162
info.bologna@accmed.org
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