UNIFIED COVID-19 ALGORITHMS - LAST UPDATED: JUNE 21, 2021

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UNIFIED COVID-19 ALGORITHMS - LAST UPDATED: JUNE 21, 2021
UNIFIED COVID-19
 ALGORITHMS
    LAST UPDATED: JUNE 21, 2021
DISCLAIMER
The current algorithms are based on the best evidence available in scientific literature at the
time of its formulation. However, these algorithms are not a comprehensive guide to all
practice questions and management options on COVID-19. This is not meant to restrict the
practitioner in using sound clinical judgement and sharing the decision with the patient, and
from considering other management options according to the patient’s particular needs and
preferences. The algorithms can serve to inform policy, but are not meant to serve as a basis
for approving or denying financial coverage or insurance claims merely because of
nonconformance with recommendations. Neither are the recommendations supposed to be
considered as legal rules for dictating certain modes of action to the exclusion of others.

                                                                                                  2
BACKGROUND
The Unified COVID-19 Algorithms is an ongoing collaboration between volunteer facilitators,
technical specialists and algorithm constructors, contributors and reviewers from different medical
organizations, and coordinated with the DOH Disease Prevention and Control Bureau. This release
reflects evidence and policy updates, as well as medical community consensus since the call of the
Health Professionals’ Alliance Against COVID-19 to re-strategize the country’s response against
COVID-19.

Each algorithm was reviewed by subject matter experts, stakeholders, as well as end- users. With
the Philippine context in perspective, the algorithms provide clear guidelines for COVID-19
management from both the community and hospital levels. Algorithms reinforce the Philippine
COVID-19 Living Recommendations. The development process was guided by evidence-based,
patient-centered, and equity-driven principles.

Work on the first version of the Unified Algorithms was started as early as March 2020 with a small
team of volunteer algorithm constructors and five core medical societies, facilitated by volunteers
from the Asia-Pacific Center for Evidence-Based Healthcare (APCEBH), Alliance for Improving
Health Outcomes (AIHO), and Kalusugan ng Mag-Ina (KMI). The first version was hosted by the
Philippine Society for Microbiology and Infectious Diseases (PSMID). With continued support from
PSMID, this expansion was carried out by the HPAAC Steering Committee through its network of
volunteers and the leadership of various medical professional societies.

These algorithms are subject to change as evidence emerges and guidelines are updated.
Recommendations on patient care are not absolute. Final decisions remain under the discretion of
the healthcare provider.

As the unified algorithms are utilized, end-users are enjoined to provide feedback as to their
experience with use of the algorithms in the field through: secretariat@psmid.org and
hpaac.org.ph/contact or secretariat@hpaac.org.ph.

                                                                                                  3
DEVELOPED BY
Philippine Society of Microbiology and Infectious Diseases
Philippine College of Physicians
Philippine Society of Public Health Physicians
Philippine Society of General Internal Medicine
Philippine College of Emergency Medicine
Philippine College of Occupational Medicine
Philippine Society of Hospice and Palliative Medicine
Philippine College of Chest Physicians
Philippine Society of Newborn Medicine
Philippine Academy of Pediatric Pulmonologists
Philippine Hospital Infection Control Society
Asia Pacific Center for Evidence Based Healthcare
Alliance for Improving Health Outcomes
Kalusugan ng Mag-Ina
Healthcare Professionals Alliance Against COVID-19

                                                             4
ALGORITHM CONSTRUCTORS
Dr. Alberto E. Antonio, Jr.
Dr. Fae Princess Bermudez
Dr. Johannes Paolo B. Cerrado
Dr. Alexander Leandro B. Dela Fuente
Dr. Ronna Cheska V. De Leon-Yao
Dr. Enrico Ian L. Deliso
Dr. Zashka Alexis M. Gomez
Dr. John Michael B. Hega
Dr. Sarah Reem D. Hesham Mohamed Hagag
Dr. Jan Derek D. Junio
Dr. Richard Raymund R. Ragasa
Dr. Sitti Khadija U. Salabi
Dr. Philine Aurea Grace S. Salvador
Dr. Justin Alan A. Yao
Intern Lara Mara Marielle L. Castillo
Intern Patricia S. Sy

                                         5
STEERING COMMITTEE
Dr. Marissa M. Alejandria
Dr. Maaliddin B. Biruar
Dr. Romelei S. Camiling-Alfonso
Dr. Antonio Miguel L. Dans
Dr. Pauline F. Convocar
Dr. Anna Sofia Victoria S. Fajardo
Dr. Rodney M. Jimenez
Dr. Mario M. Panaligan
Dr. Aileen T. Riel-Espina
Dr. Maria Asuncion A. Silvestre

                                     6
CONTRIBUTORS
Dr. Cybele Lara R. Abad          Dr. Maria Margarita Ballon-Malabanan
Dr. Dennis James E. Absin        Dr. Wendel Marcelo
Dr. Roselle S. Andres            Dr. Faith Joan Mesa-Gaerlan
Dr. Ann Joan D. Bandonill        Dr. Katerina Nono-Abiertas
Dr. Jubert Benedicto             Dr. Arabelle Colleen Ofina
Dr. Regina Berba                 Dr. Phil M. Pangilinan
Dr. Donna Isabel S. Capili       Dr. Michal Emy Pasaporte-Hafalla
Dr. Criselda Isable C. Cenizal   Dr. Djhoanna A. Pedro
Dr. Rumalie A. Corvera           Dr. Rommel B. Punongbayan
Dr. Marilen Evangeline M. Cruz   Dr. Josephine S. Raymundo
Dr. Luningnging P. Cubero        Dr. Neil P. Rodrigo
Dr. Guinevere Dy-Agra            Dr. Generoso Roberto
Dr. Barbara Amity Flores         Dr. Arthur Dessi E. Roman
Dr. Karin Estepa-Garcia          Dr. Rachel Rosario
Dr. Lester Sam A. Geroy          Dr. Evalyn A. Roxas
Dr. Elaisa M. Hasse              Dr. Rowena Samares
Dr. Mari Joanne Joson            Dr. Richard Henry S. Santos
Dr. Melissa M. Juico             Dr. Gerard Danielle K. Sio
Dr. Felix F. Labanda, Jr.        Dr. Rojim Sorrosa
Dr. Margaret Leachon             Dr. Arnold P. Tabun, Jr.
Dr. Aurora Gloria I. Libadia     Dr. Jeanne V. Tiangha-Gonzales
Dr. Dax Ronald O. Librado        Dr. Patrick Joseph G. Tiglao
Dr. Bryan Albert T. Lim          Dr. Ma. Esterlita V. Uy
Dr. April Llaneta                Dr. Ivan N. Villespin
Dr. Leslie Ann Luces

                                                                        7
NAVIGATION TABLE FOR COVID-19 (See Figure 1 for Instructions)

COVID-19 Classification                                                                      Triage and            Management              Discharge and
                                                                                              Testing                                      Reintegration
Asymptomatic patients                                                                        Figure A1              Figure A2                Figure A3
- No symptom but travels from or lives in areas with community transmission

COVID-19 Contacts                                                                            Figure B1              Figure B2                Figure B3
- Close contacts1 of confirmed, probable or suspected cases;

Mild COVID-19 (suspected2 or confirmed)                                                      Figure C1              Figure C2                Figure C3
- Symptoms present, with no risk factors3 and no signs of pneumonia

Moderate COVID-19 (suspected2 or confirmed)                                                  Figure D1              Figure D2                Figure D3
- Symptoms present plus risk factors3 , OR signs of pneumonia4

Severe COVID-19 (suspected2 or confirmed)                                                    Figure E1              Figure E2                Figure E3
- Symptoms present plus signs of respiratory failure5

Critical COVID-19 (suspected2 or confirmed)                                                  Figure F1              Figure F2                Figure F3
- Symptoms present plus deteriorating vital signs6

Other Algorithms

Emergency Department and Transport                                                                                  Figure G1-5

Pregnancy (H1), Labor (H2) and Newborn (H3)                                                 Figure H1                Figure H2                Figure H3

Use of Personal Protective Equipment (PPE)                                                                             Figure J

Advanced Care Planning                                                                                                Figure K

End-of-life Care                                                                                                      Figure L

Post-mortem Care                                                                                       Post-Mortem Care Guidelines

                                                                          FOOTNOTES
1 Close Contact - failed in two or more of the following exposures to a probable or confirmed case in the past 14 days: poorly ventilated indoor area,
distance < 1 meter, unprotected/no PPE, exposure >15 mins. Examples: living with or caring for a COVID-19 patient

2   COVID-19 Suspect - A person who meets the clinical AND epidemiological criteria:
     Clinical Criteria (symptoms):
      - Acute onset of fever AND cough; OR
      - Acute onset of ANY THREE OR MORE of the following signs or symptoms: Fever, cough, general weakness/fatigue, headache, myalgia, sore throat,
         coryza, dyspnea, anorexia/nausea/vomiting1, diarrhea, altered mental status
     Epidemiological Criteria
      - Residing or working in an area with high risk of transmission of virus: closed residential settings, humanitarian settings such as camp and camp-like
         settings for displaced persons; anytime within the 14 days prior to symptom onset; or
      - Residing or travel to an area with community transmission anytime within the 14 days prior to symptom onset; or
      - Working in any health care setting, including within health facilities or within the community; any time within the 14 days prior of symptom onset

3 Risk factors: age > 60 OR comorbid conditions like chronic lung disease, chronic heart disease, hypertension, chronic kidney disease, chronic neurological
conditions, diabetes, problems with the spleen, weakened immune system such as HIVm AUDS or medicines (steroid, chemotherapy), morbid obesity (BMI >
40)

4 Signs of pneumonia: difficulty of breathing, crackles on PE, Xray findings.

5 Respiratory failure: difficulty of breathing OR O2 saturation < 94 OR RR > 30

6 Hypotension, shock, diminished sensorium, ARDS, sepsis, or end organ failure
INSTRUCTIONS
HOW TO READ THE ALGORITHMS
                                     Return to Navigation

              The clinical algorithm (flow chart) is a text format that is specially suited for
representing a sequence of clinical decisions which are intended to improve and
standardize decisions in delivery of medical care. For the purpose of clarity, a typical
clinical algorithm is depicted with basic symbols that represent clinical steps in decision-
making:

              Clinical State       Decision    Y         Action            Connection
                   Box               Box                  Box                 Box

                                        N

1.   The rectangle with rounded edges depicts the current clinical state of an individual
     patient;
2.   The hexagon is decision box which contains a question answerable by yes or no; one
     arrow going to the right signifies “yes”, and one arrow going downwards signifies
     “no”;
3.   The rectangle with sharp edges depicts the action to be done; and
4.   The oval depicts connection to another algorithm in a different page.

            Note that the following algorithms are adapted from multiple guidelines as
released by the World Health Organization, Department of Health, and other societies.
This document was also reviewed by different experts with the end-goal of having a
summarized and comprehensive compilation of guidelines that will aid in management of
COVID-19 patients by healthcare workers from both the community and hospital levels.

             Lastly, while these patient-centered algorithms intend to summarize and
simplify recommendations, these may be subject to change as evidence emerges and
guidelines are updated. Any recommendations on patient care are not absolute. Final
decisions remain under the discretion of the healthcare provider.

                                              1
PART A
ASYMPTOMATIC PATIENTS
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                        10
Figure A1 – Asymptomatic COVID-19 (Triage and Evaluation)

                                                                       Return to Navigation

                       1
ASYMPTOMATIC
  patient for
   COVID-19
   clearance

                   2
 Presents with             Y
 a positive RT-
  PCR result?

          N
                   3
   Exposure by
  close contact        Y
  with a known
      case?

          N
                   4
                                                            5
  Exposure by              Y       See Figure B2
   travel from
                                  Management of
  area of high
 transmission?                       Contacts

          N
                   6                                    7                                8                            9                                10
   Exposure by
                                  Fulfills any of the                   Are there                 Enough human
  residence in a                                                                             Y                            Y
                           Y               ff?                  Y   sufficient RT-PCR              resources for              RT-PCR on Day 5-7
    community                                                                                                                  after exposure
                                    - elderly >60                   tests to cover for           additional contact
     with high
                                 - with comorbidity                  symptomatics?                    tracing?
  transmission?
          N                                N                                  N                             N
                           11                                                                                                                     12                                13

Adhere to minimum                                                                                                                                             ASYMPTOMATIC
                                                                                                                                 Positive RT-          Y
   public health                                                                                                                                                Confirmed
                                                                                                                                 PCR result?
    standards                                                                                                                                                    COVID-19

                                                                                                                                        N
                                                                                                                                                        14                               15
                                                                                                                               Complete 14-day                Ensure that contact
                                                                                                                              quarantine from last             tracing has been
                                                                                                                                day of exposure                  initiated thru
                                                                                                                                    (Day 0)                  BHERTS/ CESU/MESU

                                                                                                                                                                                    16
                                                                                                                                                               See Figure A2
                                                                                                                                                              Management of
                                                                                                                                                              Asymptomatic
                                                                                                                                                                   Cases
Figure A2 – Asymptomatic COVID-19 (Management)

                                                                                             Return to Navigation

                            1

     From Figure A1

                            2

    ASYMPTOMATIC
      Confirmed
       COVID-19

                                3
     Ensure contact
    tracing initiated
    through BHERT/
      CESU/MESU/
       employer

                        4                                5                           6                        7
         Available                   Can adequately
    separate room in        Y          monitor and           Y   Does the patient        Y
      the household                   treat patient’s            prefer to stay in            Isolate at Home a
     and with proper                clinical evolution              at home?
     air ventilation?                    at home?

             N                             N                               N         8                            9                          10                          11
                                                                                                                                                                    d
                                                                                                                            Identify close         Begin Monitoring
                                                                 Isolate at LIGTAS             Quarantine c the               contacts.                 of cases:
                                                                  COVID Center b               entire household              Refer to B1:         (Day 0 = date sample
                                                                                                                           Contacts Triage               taken)

                                                                                                                                                                         12                     13

                                                                                                                                                                                 Reclassify.
                                                                                                                                                      Patient with        Y
                                                                                                                                                                e              See Navigation
                                                                                                                                                     symptoms ?
                                                                                                                                                                                   Table
                                                                 FOOTNOTES

a
 Self-isolate at Home - Patient in home isolation must stay separate from other household members who are also in home                                        N
                                                                                                                                                                          14
quarantine. Caregivers must wear mask properly when attending to patient, observe hand hygiene, and limit duration of
                                                                                                                                                                                                15
contact. If there is no separate CR for the patient, disinfect touched surfaces and ventilate the room (e.g. exhaust, open
doors and windows) after every use.                                                                                                                                             See Figure A3
                                                                                                                                                   End monitoring and
                                                                                                                                                                                Discharge and
                                                                                                                                                     home isolation
b                                                                                                                                                                               Reintegration
  LIGTAS COVID Center - Contacts shall be provided with individual isolation rooms, separate from those who are
symptomatic. In community-based isolation, special consideration must be afforded to individuals requiring assistance with
activities of daily living e.g. elderly living alone, young children, persons with disabilities, mothers with young infants, etc.
c
    Home Quarantine - All members of the household must strictly stay at home per LGU protocol.
d Monitoring by Barangay Health Emergency Response Team (BHERT) for isolation:
-     Accomplish a Case Investigation Form (CIF) by BHERT and/or Primary Care Provider.
-     Ensure daily monitoring throughout the duration of isolation and household quarantine.
-     Facilitate home care and social safety nets as needed.
e COVID-19 common signs and symptoms – fever, cough, general weakness/fatigue, headache, myalgia, sore throat, coryza,
dyspnea, anorexia, nausea, vomiting, diarrhea, altered mental status, anosmia, ageusia/dysgeusia

                                                                                                                                                                                                     12
Figure A3 – Asymptomatic COVID-19 (Discharge and Reintegration)

                                                                     Return to Navigation

                          1

 From Figure A2

                      2

ASYMPTOMATIC
  Confirmed
   COVID-19

                              3
 Complete 10-day
isolation from day
that patient tested
      positive

                      4

 Is the patient           Y
    immuno-
               a
Compromised ?

         N
                      5                             6                           7                          8                              9

  Is the patient                                                                             Repeat
   a healthcare               Y       RT-PCR test       Y      Do RT-PCR                                       Y    Refer to Infectious
                                       available?                                            RT-PCR
     worker?                                                                                                        Disease specialist
                                                                                            Positive?

         N                                  N                                                    N             10                         11                          12
                                                                                                                      Recovered                                  c
                                                                                                                                               May return to work .
                                                                                          Discharge from       Y    ASYMPTOMATIC
                                                                                                                                                 No further tests
                                                                                            isolation b               Confirmed
                                                                                                                                                    necessary
                                                                                                                       COVID-19

                                                FOOTNOTES
        a
          Immunocompromised individuals are patients
        • On chemotherapy for cancer
        • Untreated HIV infection with CD4 T-lymphocyte count
PART B
CONTACTS
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                        14
Figure B1 – Contacts (Triage and Evaluation)

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                      1
                  a
CLOSE CONTACT
 of a Probable or
Confirmed COVID-
 19 patient in the
   past 14 days

                      2

Ensure that BHERT/
   CESU/MESU/
   Employer are
    informed

                      3                             4                              5                                   6
    Fulfils ANY                     Are there
                                                               Enough human
     of the ff:       Y        sufficient RT-PCR        Y                              Y   Option to test IF RT-
                                                                resources for
- Elderly (>60 y/o)             kits to cover for                                          PCR is accessible and
                                                              additional contact
- with comorbidity                 contacts &                                              affordable at Day 5-7
                                                                   tracing?
                               asymptomatics?

            N                             N                             N

                                                                                                                   7                            8
                                                                                                                           ASYMPTOMATIC
                                                                                             Positive RT-PCR       Y
                                                                                                                             Confirmed
                                                                                               result Test?
                                                                                                                              COVID-19

                                                                                                      N
                                                                                                                   9                       10
                                                                                            Recommend 14-                   Refer to A2:
                                                                                             day quarantine                Management of
                                                                                            from last day of               Asymptomatic
                                                                                            exposure (Day 0)                   Case

                                                                                                                   11
                                                                                                  Refer to
                                                                                                 Figure B2:
                                                                                               Management
                             FOOTNOTE                                                           of Contacts

        a
          Close Contact: failed in two or more of the
        following exposures to a probable or confirmed case
        in the past 14 days: poorly ventilated indoor area,
        distance < 1 meter, unprotected/no PPE, exposure
        >15 mins. Examples: living with or caring for a
        COVID-19 patient

                                                                                                                                                    15
Figure B2 – Contacts (Management)

                                                         Return to Navigation

                        1
 From Figure A1
       OR
    Figure B1

                        2

  Exposure by
    travel or
 Close Contact

                    3                            4                           5                                 6
     Available               Can adequately
separate room in        Y      monitor and           Y   Does the patient        Y     Quarantine at
  the household               treat patient’s            prefer to stay in                      a
                                                                                         Home
 and with proper            clinical evolution              at home?
 air ventilation?                at home?

           N                       N                                N
                                                                             7
                                                                                                           8                          9                  10
                                                                                         COVID-19                                          Reclassify.
                                                           Quarantine at                                    Y
                                                                                       common signs                   Suspect                 See
                                                           LIGTAS COVID
                                                                     b                     and                       COVID-19              Navigation
                                                              Center
                                                                                       symptoms? d                                           Table

                                                                                                  N        11
                                                                                          Complete
                                                                                       recommended
                                                                                         quarantine
                                                                                           period

                                                                                        Refer to Figure
                                                                                                          12
                                                                                        B3: Discharge
                                                                                              and
                                                                                         reintegration
                                                                                          of contacts

                                                                  FOOTNOTES
       a
        Self-quarantine at Home - Members of the same household who have been exposed must strictly separate from non-
       exposed members and stay at home per LGU protocol. If there is no separate CR for the patient, disinfect touched
       surfaces and ventilate the room (e.g. exhaust, open doors and windows) after every use.
       b LIGTAs COVID Center – Contacts shall be provided with individual quarantine rooms separate from those who are
       symptomatic. In community-based quarantine, special consideration must be attributed to individuals requiring assistance
       with activities of daily living (e.g., elderly living alone, young children, persons with disabilities, mothers of young infants)
       c
           Monitoring by Barangay Health Emergency Response Team (BHERT) for quarantine:
       -    Accomplish a Case Investigation Form (CIF) by BHERT and/or Primary Care Provider.
       -    Ensure daily monitoring throughout the duration of isolation and household quarantine.
       -    Facilitate home care and social safety nets as needed.
       d
        COVID-19 common signs and symptoms – fever, cough, general weakness/fatigue, headache, myalgia, sore throat, coryza,
       dyspnea, anorexia, nausea, vomiting, diarrhea, altered mental status, anosmia, ageusia/dysgeusia

                                                                                                                                                              16
Figure B3 – Contacts (Discharge and Reintegration)

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                                                       1

                                From Figure B2

                                                     2

                                 Close Contact
                               under quarantine

                                                   3

                              End monitoring and
                               home quarantine
                                 after 14 days

                                                     4

                             Discharge; No further
                               testing necessary;
                             May return to worka

                                       FOOTNOTE

   a RT-PCR tests, rapid antibody tests, and rapid antigen tests are NOT
   recommended for work clearance.

   Refer to workplace guidelines
   1. DOLE-DTI Joint Memorandum Circular 20-04-A (August 15, 2020)
   2. DOH Workplace Handbook as of September 30, 2020

                                                                           17
PART C
MILD COVID-19
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                         18
1                                   Figure C1 – Mild Covid-19 (Triage and Evaluation)
           MILD
         Suspect a
         COVID-19
                                                                                           Return to Navigation
                               2
        Isolate and
     facilitate testing.
           Inform
                      b
     close contacts .

                           3                                   4
        RT-PCR test
       available in a
                               Y
         nationally                     Do RT-PCR test
         accredited
        laboratory?

                 N         5                                  6                             7

      Rapid antigen            Y                               Y                                   Y
      test available?                  Do Rapid Ag Test                      Positive?

                N                                                                  N        8
                                                                             Previous
                                                                                   b
                                                                           contact or                Y
                                                                           linked to a
                                                                                   c
                                                                            cluster of
                                                                               cases

                                                                                    N       9
                                                                              Recent
                                                                           anosmia or
                                                                             ageusia
                                                                                                   Y
                                                                             without
                                                                            identified
                                                                              cause?
                                                                                   N          10                               11                        12                       13                               14
                                                                          IF chest imaging
                                                                                                   Y       RT-PCR/Antigen       Y    Repeat RT-PCR/                  Positive                     MILD
                                                                           was done, are                                                                                               Y
                                                                                                          test available and          Antigen Test;                                             Confirmed
                                                                       findingsd suggestive                                                                      RT-PCR/Antigen
                                                                                                               feasible?            Maintain isolation            test results?                 COVID-19
                                                                            of COVID-19?

                                                                                   N            15                    N                                                    N      16                          17
                                                                                                                                                                                           Ensure that contact
                                                                          Non-COVID ARI                                                                               MILD
                                                                                                                                                                                            tracing has been
                                                                           (Usual Care)                                                                             Probable
                                                                                                                                                                                              initiated thru
                                                                                                                                                                    COVID-19
                                                                                                                                                                                               CESU/MESU

                                                                                                                                                                                                             18
                                                                                                                                                                                              See Figure C2
                                                                                                     FOOTNOTES
a Suspect                                                                                                                                                                                   for Management
                                                                                                                                                                                                 of Mild
I. A person who meets the clinical AND epidemiological criteria:
1. Clinical criteria:
• Acute onset of fever AND cough; OR                                                                        b
• Acute onset of ANY THREE OR MORE of the following signs or symptoms: fever, cough,                         Close Contact
     general weakness/fatigue, headache, myalgia, sore throat, coryza, dyspnea,                             •  Failed in two or more of the following exposures to a probable or confirmed case in the past 14 days:
     anorexia/nausea/vomiting, diarrhea, altered mental status.                                                poorly ventilated indoor area, distance < 1 meter, unprotected/no PPE, exposure >15 mins
AND                                                                                                         • Examples: living with or caring for a COVID-19 patient
2. Epidemiological criteria:                                                                                c
• Residing or working in an area with a high risk of transmission of the virus: for example,                 A cluster is a group of symptomatic individuals linked by time, geographic location and common exposures,
     closed residential settings and humanitarian settings, such as camp and camp-like settings for         containing at least one RT-PCR confirmed case OR at least two epidemiologically linked, symptomatic
     displaced persons, anytime within 14 days prior to symptom onset; OR                                   {meeting clinical criteria in footnote b) persons with positive Rapid Antigen Test.
• Residing in or travel to an area with community transmission anytime within 14 days prior to              d Typical chest imaging findings of COVID-19:
     symptom onset; OR
• Working in a health setting, including within health facilities and within households, anytime            1. Chest radiography - hazy opacities, often rounded in morphology, with peripheral and lower lung
     within 14 days prior to symptom onset.                                                                 distribution;
                                                                                                            2. Chest CT - multiple bilateral ground glass opacities, often rounded in morphology, with peripheral and
II. A patient with severe acute respiratory illness (SARI: acute respiratory infection with history of      lower lung distribution;
fever or measured fever of > 38 degree Celsius; and cough; with onset within the last 10 days; and          3. Lung ultrasound - thickened pleural lines, B lines, consolidative patterns with or without air
which requires hospitalization)                                                                             bronchograms.                                                                                                19
Figure C2 – Mild Covid-19 (Management)

                  1                                    2                        Return to Navigation
                                      MILD
                                   Probable or
From Figure C1
                                   Confirmed
                                    COVID-19

                                                       3
                              Ensure that contact
                               tracing has been
                                 initiated thru
                              BHERTs/CESU/MESU
                                   /Employer

                                                       4                             5                                     6                               7
                                     Available                    Can adequately
                                  separate room                     monitor and                           Does the
                                      in the               Y       treat patient’s       Y              patient prefer         Y                      a
                                                                                                                                    Isolate at Home
                                  household and                        clinical                          to stay in at
                                  with proper air                   evolution at                           home?
                                   ventilation?                        home?
                                          N                                N                                    N
                                                                                                                               8                            9

                                                                                                                                               c
                                                                                                       Isolate at LIGTAS            Quarantine the
                                                                                                                      b             entire household
                                                                                                        COVID Center

                                                                                                                                                           10
                                                                                                                                      Identify close
                                                                                                                                        contacts .
                                                                                                                                       Refer to B1:
                                                                                                                                     Contacts Triage

                                                 FOOTNOTES
   a Self-isolate at Home - Patient in home isolation must stay separate from other household                                                               11
   members who are also in home quarantine. Caregivers must wear mask properly when attending to                                                       d
                                                                                                                                   Begin Monitoring
   patient, observe hand hygiene, and limit duration of contact. If there is no separate CR for the
                                                                                                                                        of cases
   patient, disinfect touched surfaces and ventilate the room (e.g. exhaust, open doors and windows)
   after every use.
   b
     LIGTAS COVID Center - In community-based isolation, special consideration must be afforded to
   individuals requiring assistance with activities of daily living e.g. elderly living alone, young
   children, persons with disabilities, mothers with young infants, etc.                                                                                    12
                                                                                                                                   Provide symptomatic
   c Home Quarantine - All members of the household must strictly stay at home per LGU protocol.                                      treatment. No
                                                                                                                                    antibiotic needed.
   d                                                                                                                                 No prophylaxis.
       Monitoring by Barangay Health Emergency Response Team (BHERT) for isolation:
   -    Accomplish a Case Investigation Form (CIF) by BHERT and/or Primary Care Provider.
   -    Ensure daily monitoring throughout the duration of isolation and household quarantine.
   -    Facilitate home care and social safety nets as needed.
                                                                                                                                                           13                           14
   e
     Improvement of clinical status:
   - No fever for at least 24 hours without antipyretics                                                                             Worsening signs           Y   Reclassify. Return
   - Respiratory symptoms reduced significantly                                                                                      and symptoms?                   to navigation
   - CXR shows significant improvement if available                                                                                                                      table

                                                                                                                                               N
                                                                                                                                                                                        16
                                                                                                                                                            15
                                                                                                                                                                        Refer to
                                                                                                                                      Improvement                      Figure C3
                                                                                                                                    of Clinical Statuse                Discharge
Figure C3 – Mild Covid-19 (Discharge and Reintegration)

                                                         Return to Navigation

                                                                                                             FOOTNOTES
                         1
                                                                      a
                                                                        Improvement of clinical status
                                                                      • No fever or use of antipyretic for at least 3 days
From Figure C2                                                        • Respiratory symptoms reduced significantly
                                                                      • CXR (if available) shows significant improvement
                                                                      b Immunocompromised individuals are patients
                                                                      • On chemotherapy for cancer
                         2                                            • Untreated HIV infection with CD4 T-lymphocyte count
PART D
MODERATE COVID-19
 Return to Navigation

                        22
Figure D1 – Moderate COVID-19 (Triage and Evaluation)

                                                                                            Return to Navigation

                            1
     MODERATE                                                                                                                                                           FOOTNOTES
      Suspect a                                                                                                                      a Risk Factors: age > 60 OR any comorbid conditions as listed below:
     COVID-19
                                                                                                                                     chronic lung disease, chronic heart disease or hypertension
                                                                                                                                     chronic kidney disease, chronic liver disease, chronic neurological conditions
                                                                                                                                     diabetes, problems with the spleen, morbid obesity (BMI > 40)
                        2                                3                             4                                             weakened immune system such as HIV or AIDS, or medicines such as steroid
                                Recommend admit                                                                                      tablets or chemotherapy
                                                               HESU to inform
 With pneumonia
                            Y        patient. b                                                                                      b
                                                             CESU/MESU so that                                                         Administer acute care for the patient while considering admission and service
or other indications            Inform and prepare
                                                             contact tracing can                                                     capability. Service capability as basis for admission can depend on multiple
   for admission?                    patient for
                                                               be anticipated.                                                       factors including: (1) best clinical judgement of the health provider (2)
                                transport (Figure G)
                                                                                                                                     appropriateness of health care facility (3) geographical
            N                                                                                                                        access to the next higher level facility (4) patient context.
                            5                            6                         7                                                 c
                                                                                                                                      Close Contact: Failed in two or more of the following exposures to a probable
                                Isolate and facilitate        RT-PCR available                                                       or confirmed case in the past 14 days: poorly ventilated indoor area, distance < 1
       May opt                                                                         Y
                                       testing.                in a nationally                                                       meter, unprotected/no PPE, exposure >15 mins
    NOT to admit
                                    Inform close                 accredited                                                          Examples: living with or caring for a COVID-19 patient
(e.g. during a surge)                                            laboratory?
                                      contacts.
                                                                                                                                     d
                                                                                                                                       A cluster is a group of symptomatic individuals linked by time, geographic
                                                                       N                                         9                   location and common exposures, containing at least one RT-PCR confirmed case
                                                                                   8                                                 OR at least two epidemiologically linked, symptomatic {meeting clinical criteria in
                                                                                                                                     footnote b) persons with positive Rapid Antigen Test.

                                                             Rapid Antigen test        Y                                             e
                                                                                                                                       Typical chest imaging findings of COVID-19:
                                                                 available?                       Do Test
                                                                                                                                     1. Chest radiography - hazy opacities, often rounded in morphology, with
                                                                                                                                     peripheral and lower lung distribution;
                                                                                                                                     2. Chest CT - multiple bilateral ground glass opacities, often rounded in
                                                                       N                                                             morphology, with peripheral and lower lung distribution;
                                                                                                                 10                  3. Lung ultrasound - thickened pleural lines, B lines, consolidative patterns with
                                                                                                                                     or without air bronchograms.

                                                                                                 Positive
                                                                                                                      Y
                                                                                                 result?

                                                                                                       N
                                                                                                                 11
                                                                                                 Previous
                                                                                               contactc or            Y
                                                                                               linked to a
                                                                                                       d
                                                                                               cluster of
                                                                                                  cases?

                                                                                                        N        12

                                                                                                Recent
                                                                                           anosmia or ageusia         Y
                                                                                                without
                                                                                            identified cause?

                                                                                                       N
                                                                                                                 13                        14                         15                           16                         17
                                                                                              IF chest imaging                                       Repeat RT-PCR/
                                                                                               was done, are          Y    RT-PCR/Antigen       Y     Antigen Test;
                                                                                                                                                                                    Positive
                                                                                                                                                                                                        Y
                                                                                                                                                                                                               MODERATE
                                                                                                    e                     test available and                                    RT-PCR/Antigen                 Confirmed
                                                                                           findings suggestive                                          Maintain
                                                                                                                               feasible?                                         test results?                 COVID-19
                                                                                                of COVID-19?                                            isolation

                                                                                                       N         18                  N                                                    N         19                       20

                                                                                                                                                                                                            Ensure that contact
                                                                                              Non-COVID ARI                                                                       MODERATE
                                                                                                                                                                                                             tracing has been
                                                                                               (Usual Care)                                                                        Probable
                                                                                                                                                                                                               initiated thru
                                                                                                                                                                                  COVID-19                  HESU/CESU/MESU

                                                                                                                                                                                                                             21
                                                                                                                                                                                                              See Figure D2.1
                                                                                                                                                                                                             for Management
                                                                                                                                                                                                            of Moderate Cases
Figure D2.1 – Moderate COVID-19 (Outpatient Management)

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                           1

    From Figure D1

                                                                                                                                                    FOOTNOTES
                           2                                                                            a
                                                                                                          Administer acute care for the patient while considering admission and service
     MODERATE                                                                                           capability. Service capability as basis for admission can depend on multiple factors including: (1)
    Confirmed or                                                                                        best clinical judgement of the health provider (2) appropriateness of health care facility (3)
      Probable                                                                                          geographical access to the next higher level facility (4) patient context.
     COVID-19                                                                                           b
                                                                                                         Isolate at home Patient in home isolation must stay separate from other household members
                                                                                                        who are also in home quarantine. Caregivers must wear mask properly when attending to
                         3                                                                              patient, observe hand hygiene, and limit duration of contact. If there is no separate CR for the
                                                             4                          5               patient, disinfect touched surfaces and ventilate the room (e.g. exhaust, open doors and
                                      MODERATE
       Was the                                                                                          windows) after every use.
                                     Confirmed or                  See Figure D2.2 for
       patient                 Y                                 Inpatient Management                   c
                                       Probable                                                           LIGTAS COVID Center - In community-based isolation, special consideration must be afforded
                  a                    COVID-19                    of Moderate Cases
      admitted?                                                                                         to individuals requiring assistance with activities of daily living e.g. elderly living alone, young
                                      (Inpatient)                                                       children, persons with disabilities, mothers with young infants, etc.
             N                                                                                          d
                           6                                                                              Home Quarantine - All members of the household must strictly stay at home per LGU
                                                                                                        protocol.
     MODERATE
Confirmed or Probable                                                                                   e
                                                                                                          Monitoring by Barangay Health Emergency Response Team (BHERT) for isolation
      COVID-19                                                                                          - Accomplish a Case Investigation Form (CIF) (by BHERT and/or Primary Care Provider
     (Outpatient)                                                                                       - Ensure daily monitoring throughout the duration of quarantine
                                                                                                        - Facilitate home care and basic needs
                           7                                                                            f
                                                                                                          Improvement of clinical status:
    Ensure contact                                                                                      - No fever for at least 24 hours without antipyretics
   tracing initiated                                                                                    - Respiratory symptoms reduced significantly
   through BHERT/                                                                                       - CXR shows significant improvement if available
     CESU/MESU/
      employer

                       8                                 9                              10                             11

   Available separate               Can adequately
                               Y                             Y     Does the patient
 room in the household             monitor and treat
                                                                    prefer to stay
                                                                                            Y    Isolate at home
                                                                                                                   b
    and with proper                 patient’s clinical
     air ventilation?                                                 at home?
                                   evolution at home?

             N                               N                               N              12                                                                                            15
                                                                                                                       13                           14
                                                                                                                                   Identify close
                                                                    Isolate in LIGTAS             Quarantine the                     contacts .                                     e
                                                                                                                                                                Begin Monitoring
                                                                     COVID Centerc               entire householdd                  Refer to B1:                     of cases
                                                                                                                                  Contacts Triage

                                                                                                                                                                                          16

                                                                                                                                                                Provide symptomatic
                                                                                                                                                                   treatment. No
                                                                                                                                                                 antibiotic needed.
                                                                                                                                                                  No prophylaxis.

                                                                                                                                                                                         17
                                                                                                                                                                                                                        18

                                                                                                                                                                                              Y    Reclassify patient.
                                                                                                                                                                Patient worsening?
                                                                                                                                                                                                  See Navigation Table

                                                                                                                                                                            N
                                                                                                                                                                                          19                            20
                                                                                                                                                                                                    See Figure D3 for
                                                                                                                                                                    Improvement                      Discharge and
                                                                                                                                                                                     f
                                                                                                                                                                  of Clinical Status                Reintegration of
                                                                                                                                                                                                    Moderate Cases
Figure D2.2 – Moderate COVID-19 (Inpatient Management)

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                                      1
                                                                                    FOOTNOTES
           From Figure D2.1                                a Informed consent is needed BEFORE using COVID-19
                                                           investigational drugs and interventions in trials or
                                                           compassionate use.

                                      2                    b
                                                            Investigational Drugs For Moderate COVID-19 – Individual
               MODERATE                                    hospitals will have lists of trials they are involved in.
              Confirmed or
                                                           c Improvement of clinical status:
                Probable
                COVID-19                                   - Afebrile for at least 24 hours without antipyretics
               (Inpatient)                                 - Respiratory symptoms reduced significantly
                                                           - CXR shows significant improvement if available

                                  3
               Consider
             Advance Care
           Planning (Figure K)

                                          4

                Continue
            supportive therapy

                                          5

          Consider participation
                                a,b
            in a clinical trial

                                      6
                 Consider
           compassionate use
            of investigational
                       a,b
                 Drugs

                                      7                              8

                                          Y    Reclassify patient.
           Patient worsening?
                                              See Navigation Table

                       N
                                      9                              10
                                                 See Figure D3 for
             Improvement of                       Discharge and
              Clinical Statusc                    Reintegration
                                                of Moderate Cases
Figure D3 – Moderate COVID-19 (Discharge and Reintegration)

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                         1
                                                                                                                FOOTNOTES
From Figure D2.1
       OR                                                                a Improvement of clinical status
   Figure D2.2                                                           • No fever or use of antipyretic for at least 3 days
                                                                         • Respiratory symptoms reduced significantly
                                                                         • CXR (if available) shows significant improvement
                         2                                               b
                                                                           Immunocompromised individuals are patients
   Improving                                                             • On chemotherapy for cancer
  MODERATE                                                               • Untreated HIV infection with CD4 T-lymphocyte count
PART E
SEVERE COVID-19
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                         27
1
                                         Figure E1 – Severe COVID-19 (Triage and Evaluation)
     SEVERE
     Suspect
    COVID-19
                                                                       Return to Navigation

                        2
                                                                                                                                   FOOTNOTES
                    a
Stabilize patient                                                                        a
                                                                                           Administer acute care for the patient while considering admission and service
                                                                                         capability. Service capability as basis for admission can depend on multiple factors including:
                                                                                         (1) Best clinical judgement of the health provider
                                                                                         (2) Appropriateness of health care facility
                        3                                                                (3) Geographical access to the next higher level facility
  See Figure K                                                                           (4) Patient context
      for                                                                                b Close contact: A person who failed in two or more of the following exposures to a probable or
 Advance Care
   Planning                                                                              confirmed case:
                                                                                         - Poorly ventilated indoor area
                                                                                         - Distance less than 1 meter
                                             5                                           - Unprotected/no PPE
                        4   COVID-19 test                                                - Exposure >15 mins
  See Figure G
  Emergency
                            available in a       Y                                       c
                              nationally                                                   A cluster is a group of symptomatic individuals linked by time, geographic location and common
 Department &                                                                            exposures, containing at least one RT-PCR confirmed case OR at least two epidemiologically
                             accredited
   Transport                                                                             linked, symptomatic {meeting clinical criteria in footnote b) persons with positive Rapid Antigen
                             laboratory?
                                                                                         Test.
                                     N                                          7
                                             6                                           d
                                                                                          Typical chest imaging findings of COVID-19:
                                                                                         -  Chest radiography – hazy opacities, often rounded in morphology, with peripheral and lower
                            Rapid Ag test        Y                                          lung distribution
                             available?                    Do Test                       - Chest CT – multiple bilateral ground glass opacities, often rounded in morphology, with
                                                                                            peripheral and lower lung distribution;
                                                                                         - Lung ultrasound – thickened pleural lines, B lines, consolidative patterns with or without air
                                                                                            bronchograms.
                                    N
                                                                            8

                                                           Positive             Y
                                                           result?

                                                                 N
                                                                            9
                                                           Previous
                                                                 b
                                                         contact or             Y
                                                         linked to a
                                                                 c
                                                          cluster of
                                                            cases?

                                                                N
                                                                           10
                                                          Recent
                                                     anosmia or ageusia         Y
                                                          without
                                                      identified cause?

                                                                N
                                                                           11                            12                         13                       14                                 15

                                                        IF chest imaging
                                                                                Y    RT-PCR/Antigen       Y    Repeat RT-PCR/                   Positive                    SEVERE
                                                         was done, are
                                                              d                     test available and          Antigen Test;
                                                                                                                                                                  Y
                                                     findings suggestive                                                                    RT-PCR/Antigen                 Confirmed
                                                          of COVID-19?                   feasible?            Maintain isolation             test results?                 COVID-19

                                                                N                                                                                     N
                                                                           16                   N                                                            17                                 18
                                                                                                                                                                       Ensure that contact
                                                                                                                                                SEVERE
                                                        Non-COVID ARI                                                                                                   tracing has been
                                                                                                                                               Probable
                                                         (Usual Care)                                                                                                     initiated thru
                                                                                                                                               COVID-19
                                                                                                                                                                       HESU/CESU/MESU

                                                                                                                                                                                           19
                                                                                                                                                                         See Figure E2
                                                                                                                                                                       for Management
                                                                                                                                                                           of Severe
1
                                             Figure E2 – Severe COVID-19 (Management)
    From Figure E1

                                                             Return to Navigation
                             2
      SEVERE
Suspect, Probable or
    Confirmed
     COVID-19

                             3
      Refer to
                                                                                      FOOTNOTES
 Pulmonologist and
 Infectious Disease                                  a
                                                      Informed consent is needed BEFORE using COVID-19 investigational
      Specialist                                     drugs and interventions in trials or compassionate use.
                                                     b Investigational drugs for Severe COVID-19
                             4                       - Individual hospitals will have lists of trials they are involved in.
 Secure Advanced                                     c Improvement of clinical status
   Care Planning
                                                     -   No fever or use of antipyretic for at least 24 hours
   (See Figure K)                                    -   Respiratory symptoms reduced significantly
                                                     -   CXR (if available) shows significant improvement

                             5

 Confirm Advanced
     Directives

                             6

   Give LMWH as
thromboprophylaxis

                             7

Give Dexamethasone
  6 mg IV x 10 days

                             8
Consider participation
  in clinical trial OR
 compassionate use
  of investigational
              a, b
       Drugs

                         9                      10                          11                                      12
                                                                                         Not recommended
                             Y                           Patient is on
                                 Does patient    Y                               Y       to start Remdesivir
     SpO2 < 94%                                            invasive
                                  require O2                                             (Remdesivir can be
     at room air?                                         mechanical
                                   support?                                          continued if initiated prior
                                                          ventilation?
                                                                                       to invasive ventilation)

             N                           N                       N
                                                                             13

                                                     Consider addition of
                                                         Remdesivir
                                                        in treatment

                                                                                                              14                                  15                         16
                                                                                                                   Y     Consider reclassifying          See Navigation
                                                                                           Deteriorating
                                                                                           clinical status?                  as CRITICAL                      Table
                                                                                                                               COVID-19

                                                                                                     N                                            17                         18
                                                                                                                           Improvement of                 See Figure E3
                                                                                                                                            c          Discharge of Severe
                                                                                                                            Clinical Status                 COVID-19
Figure E3 – Severe COVID-19 (Discharge and Reintegration)

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                                                                                                           FOOTNOTES
                                                                  a
                         1                                            Improvement of clinical status
                                                                  •     No fever or use of antipyretic for at least 3 days
                                                                  •     Respiratory symptoms reduced significantly
 From Figure E2                                                   •     CXR (if available) shows significant improvement
                                                                  b Immunocompromised individuals are patients:
                                                                  •       On chemotherapy for cancer
                                                                  •       With untreated HIV infection with CD4 T-lymphocyte count
PART F
CRITICAL COVID-19
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                         31
Figure F1 – Critical COVID-19 (Triage and Evaluation)

                       1
                                                                                         Return to Navigation
     CRITICAL
                                                                                                                                                                         FOOTNOTES
      Suspect
     COVID-19                                                                                                                   a
                                                      3                                                                           Administer acute care for the patient while considering admission and service
                                                                                                                                capability. Service capability as basis for admission can depend on multiple factors
                                                                                                                                including: (1) best clinical judgement of the health provider (2) appropriateness of health
                       2                                                        4                                5              care facility (3) geographical access to the next higher level facility (4) patient context.
                               Cardiopulmonary                                                                                  b
                                                                                                                                  RT-PCR
Patient gasping, not       Y      (CP) Arrest,
    breathing or               COVID-19 Suspect           Is the patient in a        Y     See Figure F2.1                      - Nasopharyngeal swab, saliva drool/spit samples can be used
                                                               hospital?                 for Advanced ACLS                      c Rapid Antigen Test
  without pulse?                 until proven
                                   otherwise                                                                                    - Sample collected should be via nasopharyngeal swab
                                                                                                                                - Should not be used in settings with an expected low prevalence of disease, and for
           N                                                         N                                                          populations with no known exposure
                           6                      7                                                                  8          d Close Contact: Two or more of the following exposures to a probable or confirmed case
                 a              See Figure G2
 Stabilize patient                                                                          See Figure G1                       in the past 14 days: poorly ventilated indoor area, distance < 1 meter, unprotected/no PPE,
                                 Emergency
    Prepare for                                                                           for Out of Hospital                   exposure >15 mins
                                and Transport
transport if needed                                                                         Cardiac Arrest                      Examples: living with or caring for a COVID-19 patient
                                 Algorithms
                                                                                                                                e
                                                                                                                                 A cluster is a group of symptomatic individuals linked by time, geographic location and
                                                                                                                                common exposures, containing at least one RT-PCR confirmed case OR at least two
                                                                                    10                                          epidemiologically linked, symptomatic persons with positive Rapid Antigen Test.
                                                  9
                                  See Figure K            COVID-19 RT-PCR                                                       f Typical chest imaging findings of COVID-19:
                               for Advance Care
                                                                                     Y
                                                          test available and                                                    1. Chest radiography - hazy opacities, often rounded in morphology, with peripheral and
                                    Planning                            b                                                       lower lung distribution;
                                                             feasible?
                                                                                                                                2. Chest CT - multiple bilateral ground glass opacities, often rounded in morphology, with
                                                                                                                                peripheral and lower lung distribution;
                                                                     N          11                              12              3. Lung ultrasound - thickened pleural lines, B lines, consolidative patterns with or without
                                                                                                                                air bronchograms.
                                                                                              Do test;
                                                            Rapid Antigen
                                                                                     Y   Maintain isolation
                                                          test available and
                                                                                          of symptomatic
                                                               feasible c
                                                                                               patient

                                                                     N                                           13
                                                                                           Positive RT-
                                                                                         PCR/Antigen Test
                                                                                                                 Y
                                                                                             results?

                                                                                                    N            14
                                                                                          Close Contact d
                                                                                           or linked to a        Y
                                                                                             COVID-19
                                                                                             clustere?

                                                                                                    N            15
                                                                                            With recent
                                                                                            anosmia or
                                                                                                                 Y
                                                                                           ageusia in the
                                                                                         absence of other
                                                                                         identified cause?
                                                                                                    N           16                        17                             18                        19                           20
                                                                                             IF chest
                                                                                          imaging done,                   RT-PCR/Antigen       Y     Repeat RT-PCR/                   Positive                    CRITICAL
                                                                                                                 Y                                                                                      Y
                                                                                             findings                    test available and           Antigen Test;               RT-PCR/Antigen                 Confirmed
                                                                                                     f
                                                                                          suggestive of                       feasible?             Maintain isolation             test results?                 COVID-19
                                                                                            COVID-19?
                                                                                                    N                                N                                                      N
                                                                                                              21                                                                                   22                           23
                                                                                                                                                                                                             Ensure that contact
                                                                                                                                                                                     CRITICAL
                                                                                            NON-COVID                                                                                                         tracing has been
                                                                                            (Usual Care)                                                                             Probable
                                                                                                                                                                                                                initiated thru
                                                                                                                                                                                     COVID-19
                                                                                                                                                                                                                 CESU/MESU

                                                                                                                                                                                                                                24
                                                                                                                                                                                                                 See Figure F2
                                                                                                                                                                                                             for Management of
                                                                                                                                                                                                                   CRITICAL

                                                                                                                                                                                                        16
Figure F2 – Critical COVID-19 (Management)

                    1                                   Return to Navigation

 From Figure F1

                                                                                                                FOOTNOTES

                                                                          a The advance directive should always be reviewed with the family.
                    2
                                                                          See Figure K for Advance Care Planning
    CRITICAL
Suspect, Probable                                                         Guidelines on Advance Directives (DNR)
  or Confirmed
    COVID-19                                                              1. Medical team may withhold CPR on critically ill patients with NO reasonable
                                                                          chance of recovery (i.e., ARDS secondary to high-risk pneumonia and
                                                                          unresponsive to treatment, refractory septic shock, multi-organ failure)

                    3                                                     2. Free and informed decision for DNR made by competent patient through an
                                                                          advanced directive should be followed
Secure Advanced
   Directives                                                             3. Without advanced directive, the free and informed decision of proxy of an
    (Figure K)                                                            incompetent patient should be followed

                                                                          4. Without patient’s or proxy’s decision, the medical team can decide based on
                    4                                                     futility, the best interest of patient, and scarcity of resources

Confirm Advance                                                           5.Efforts to provide spiritual care and counseling to the patient and family must
  Directive as                                                            be done
             a
  Necessary                                                               b
                                                                              Improvement of clinical status
                                                                          -     No fever or use of antipyretic for at least 24 hours
                                                                          -     Respiratory symptoms reduced significantly
                    5                           6                         -     CXR (if available) shows significant improvement

  Patient not                   See Figure F2.1
  breathing or
                        Y   for Advanced Cardiac
 without pulse?               Life Support (ACLS)

         N
                                                    7                              8
                              Patient develops
                                                              See Figure F2.2
                             respiratory distress        Y   for Management
                                AND unstable
                                                                  of ARDS
                                 vital signs?

                                        N                                         9                                    10

                                                             Patient develops                   See Figure F2.3
                                                                                       Y          for Sepsis
                                                                 sepsis or
                                                              septic shock?                      Management

                                                                      N
                                                                                                                      11                             12

                                                                                                 Irreversible               Y     See Figure L for
                                                                                              respiratory failure?                End of Life Care

                                                                                                          N
                                                                                                                      13                             14

                                                                                               Patient expired?
                                                                                                                           Y     See Figure M for
                                                                                                                                Post Mortem Care

                                                                                                          N           15
                                                                                                                                                     16

                                                                                                                                    Refer to
                                                                                                 Improvement
                                                                                                                  b                 Figure F3
                                                                                               of clinical status
                                                                                                                                  for discharge
Figure F2.1 – Critical COVID-19 (Advanced Cardiac Life Support or ACLS)
                             1

   From Figure F2                                                                        Return to Navigation

                                                                                                                                                         FOOTNOTES
                             2
                                                                                                             a
                                                                                                               The advance directive should always be reviewed with the family. See Figure K for
    CRITICAL
 COVID-19 Patient                                                                                            Advance Care Planning
    in Arrest                                                                                                Guidelines on Advance Directives (DNR)
                                                                                                             1. Medical team may withhold CPR on critically ill patients with NO reasonable chance of
                                                                                                             recovery (i.e., ARDS secondary to high-risk pneumonia and unresponsive to treatment,
                             3                                                                               refractory septic shock, multi-organ failure)
                                                                                                             2. Free and informed decision for DNR made by competent patient through an advanced
                                                                                                             directive should be followed
      Advance                    Y
                    a                                                                                        3. Without advanced directive, the free and informed decision of proxy of an incompetent
directive available                                                                                          patient should be followed
                                                                                                             4. Without patient’s or proxy’s decision, the medical team can decide based on futility, the
                                                                                                             best interest of patient, and scarcity of resources
            N                                                                                                5.Efforts to provide spiritual care and counseling to the patient and family must be done
                         4                               5
                                                                                                             b The medical team becomes decision maker in the absence of proxy
  Proxy decision                          Does the               Y
                                 Y
                     b                 directive favor                                                       c
maker is available                                                                                             Early Intubation
                                       resuscitation?
                                                                                                             Do early intubation with most experienced person with the use of video-guided
                                                                                                             laryngoscope. Can start bag-mask ventilation with HEPA filter.

             N                                  N                                                            d Hands-only CPR
                         6                               7
                                                                                                             Chest compressions only. Consider use of mechanical compressor if available to eliminate
                                        Consider                                                             need for manual compressions. Cover patient's mouth and nose with cloth/barrier. Limit
                             Y          Do-Not-                                                              number of team to limit exposure. Continue CPR on the following mechanical ventilator
Recovery unlikely?
                                       Resuscitate                                                           settings: mechanical ventilator at FiO2 100%, back-up rate 12/min. Avoid bag-mask
                                         (DNR)                                                               ventilation (BMV).

            N
                                                             8
                                          Provide
                                     postmortem care
                                     and bereavement
                                         support

                                                                                         9                           10

                                                                     Initiate CPR with         On mechanical              Y
                                                                        proper PPE              ventilator?

                                                                                                       N
                                                                                                                     11                                 12                         13

                                                                                                                                                    c         Continue CPR on
                                                                                              Early intubation            Y   Do early intubation               mechanical
                                                                                                  possible?                     with proper PPE                ventilator a, d

                                                                                                       N
                                                                                                                      14                                                          15                              16

                                                                                                                                                                 Return of                     Continue
                                                                                                                 d                                                                 Y         supportive or
                                                                                             Do hands only CPR                                                 spontaneous
                                                                                                                                                                circulation?                  critical care

                                                                                                                                                                      N
                                                                                                                                                                                  17                              18
                                                                                                                                                                  Provide                       Reassess.
                                                                                                                                                             postmortem care                 See Figure F2
                                                                                                                                                             and bereavement                Management of
                                                                                                                                                                 support                   Critical of Patients

                                                                                                                                                                                 19
                                                                                                                                                                                                      34
                                                                                                                                                              See Figure M for
                                                                                                                                                             Post Mortem Care
Figure F2.2 – Critical COVID-19 (Management of Acute Respiratory Distress Syndrome or CARDS)

                                                                           Return to Navigation

                                                                                                               FOOTNOTES

                                                          a                                                      d Intensive pulmonary care bundle
                                                            Oxygen support therapy
                                                          Oxygen support is delivered via face mask or non-         1. Airborne precautions should be followed
                                                          rebreather mask with hepa filter.                         • Bag-mask ventilation is not recommended, unless with hepa filter.
                                                          May use high flow nasal cannula at 40-60 L/min                 Place patient on 6L oxygen support via nasal cannula for pre-oxygenation.
                                                          overlapped with a face mask and non-invasive              • Avoid disconnecting patient from the ventilator
                                                          positive pressure ventilation in a single negative        • Nebulization is not recommended. Use metered dose inhalers.
                                                          pressure room. Maintain O2St >92%                         • Use in-line catheters for suctioning.
                        1                                                                                           •     Endotracheal intubation should be performed by a trained provider using
                                                          b                                                              the proper PPE. One-time intubation only using rapid sequence intubation
                                                            ROX Index (SpO2/FiO2)/RR
   From Figure F2                                         Perform intubation if the ROX index are less than              is ideal. Use video laryngoscope if available.
                                                          these values at the hours of checking                     2. ICU admission
                                                          2 hours - < 2.8                                           3. Conservative fluid management
                                                          6 hours - < 3.47                                          4. Give empiric antimicrobials, guided by the guidelines on Community-
                                                          12 hours - < 3.85                                              Acquired Pneumonia, only if highly suspecting bacterial co-infection.
                            2                                                                                       5. Consider neuromuscular blockade in intubated patient with moderate-
      CRITICAL                                            c                                                              severe ARDS.
                                                            Intubation
  COVID-19 Patient                                        Intubate with most experienced person with the            6. Give anticoagulation therapy.
  with respiratory                                        use of video-guided laryngoscope. Can start bag-          7. Give dexamethasone 6 mg/day for 10 days
    distress and                                          mask ventilation with HEPA filter.                        8. Refer to pulmonologist or intensivist
 unstable vital signs                                                                                               9. Initiate recruitment maneuvers and lung protection strategies
                                                                                                                    • Tidal volume 6-8mL/kg of predicted body weight
                                                                                                                    • Plateau pressure 30                                                                                                      • Consider extracorporeal life support
                                                                                                                    10. Consider investigational drugs for Critical COVID-19
                                                                                                                    • Informed consent is needed BEFORE using COVID-19 investigational drugs
                                                                                                                         and interventions in trials or compassionate use.
            N
                        4
     Peripheral
      capillary
                                Y
  oxygen saturation
Figure F2.3 – Critical COVID-19 (Management of Sepsis)

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                         1

 See Figure F2

                             2

COVID-19 Patient
 with suspected
     sepsis

                         3                            4

                     a           Y
  qSOFA > 2?                            Sepsis

         N
                         5                            6                             7                                  8
                                        Systemic                                           Consider referral to
                 b               Y   Inflammatory             Standard care for
   SIRS> 2?                                                                                  intensive care
                                       Response                   sepsis c                      specialist
                                       Syndrome

             N
                         9
                                                                                                                  10
                                                                                                Reassess.
                                                                                             See Figure F2
 Sepsis not likely
                                                                                            Management of
                                                                                           Critical of Patients

                                                              FOOTNOTES

         a
           qSOFA Variables
         -Respiratory rate >22 breaths/min
         -Altered mentation
         -Systolic blood pressure 38°C or 90 beats/min
         3.Respiratory rate >20 breaths/min, or paCO2 12,000 or 20% immature (band) forms
         c
           Standard of care for sepsis: (Intensive Care for Severe Sepsis and Septic Shock)
         1. Admit patient to the ICU.
         2. Give antimicrobials within 1 hour of initial patient assessment. Follow current Guidelines for Diagnosis and
               Treatment of CAP in Adults.
         3. Blood cultures ideally should be collected prior to antimicrobial treatment, but should not delay administration of
               antimicrobials.
         4. Early effective fluid resuscitation needed
               • Administer at least 30 mL/kg of isotonic crystalloid in adults in the first 3 hours.
               • Monitor for volume overload during resuscitation.
         5. Apply vasopressors when shock persists in the for of norepinephrine, vasopressin, or dobutamine (if with signs of
               poor perfusion and cardiac dysfunction.
         6. Maintain initial BP target as MAP > or = to 65 mmHg.
         7. Insert central venous catheters. If not available, vasopressors may be given through peripheral IV access with the
               use of a large vein.

                                                                                                                                  36
Figure F3 – Critical COVID-19 (Discharge and Reintegration)

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                         1
                                                                                                    FOOTNOTES

 See Figure F2                                                    a
                                                                    Improvement of clinical status
                                                                  • No fever or use of antipyretic for at least 3 days
                                                                  • Respiratory symptoms reduced significantly
                                                                  • CXR (if available) shows significant improvement
                         2                                        b Immunocompromised individuals are patients
   Improving                                                      • On chemotherapy for cancer
    CRITICAL                                                      • Untreated HIV infection with CD4 T-lymphocyte count
PART G
EMERGENCY DEPARTMENT
AND TRANSPORT
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                        38
Figure G1 – Management of Out-of-Hospital Cardiac Arrest (OHCA) in Adults

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                                           1

                    From Figure F1

                                          2                           3
                        CHECK
                  own safety prior to            See Figure J1 PPE
                 attending to patient.
                      Wear PPE.

                                                                      4
                                                    RECHECK
                                                  that patient is
                                               unconscious with no
                                                                  a
                                                normal breathing .

                                                                      5                            6
                                                      CALL
                                                                                  COVER
                                               Medical help or EMS              c
                                                                           Cover patient’s mouth
                                                 for Telephone-
                                                              b            and nose with mask or
                                                Assisted CPR if
                                                                                   cloth
                                                    available

                                                                                                   7                       8                                  9
                                                                                 COMPRESS                                             CONNECT.
                                                                                                           Automated           Y
                                                                            Start hands-only CPR                                    Attach AED and
                                                                                                           Defibrillator
                                                                            until EMS or medical                                     follow voice
                                                                                help arrivesd
                                                                                                            present?                   prompte.

                                                                                                                    N
                                                                                                                                                              10
                                                     FOOTNOTES                                                                       Continue CPR.
                                                                                                                                    Prepare for rapid
                                                                                                                                       transport 10
5C's of Out-of-Hospital Cardiac Arrest (Check, Call, Cover, Compress, Connect).

aCHECK for personal safety, safety of the environment and patient's status.
Abnormal Breathing- No breathing or agonal, gasping without pulse.                                                                                       11                             12
                                                                                                                                       Is Return of                 See Figure G4 .
b   CALL EMS for Telephone-Assisted CPR and follow instructions                                                                       Spontaneous             Y      Management
                                                                                                                                        Circulation                    of COVID
c   COVER the patient's mouth with mask if available or cloth and cover yourself with a mask                                            achieved?                  Patient in transit
dDo the following:
1. Place the victim flat on his back on the floor.
                                                                                                                                                N       13                              14
2. Kneel by the victim’s side.                                                                                                          Is Direct
3. Put the heel of your hand on the center of the victim’s chest.                                                                       Medical               Y     See Figure M for
4. Put your other hand on top of that hand.                                                                                             Oversight                  Post Mortem Care
5. With your arms straight, COMPRESS as hard as you can with the heels of your hands. Do it 10 times at the rate                       availablef?
of 100-120 compressions per minute. Keep going, push hard and fast and count out loud to10 over and over
again. II will stay on the phone. Keep doing it until help/dispatched ambulance arrives.
Call may be re-attempted to known institutional or local government unit emergency operations center hotlines or
follow-up with the person asked to do so; until help arrives.                                                                                                 15
                                                                                                                                      Coordinate with
e   CONNECT AED and follow voice prompt                                                                                             institutional or LGU
                                                                                                                                   Command Center for
fDirect Medical Oversight a physician overseeing the emergency medical services and Follow institutional                            transfer to hospital
protocol or local EMS Protocol
Figure G2 –Primary Transport to a Healthcare Facility*

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                                                      1

                               Patient for
                              transport to
                            healthcare facility

                                                  2                              3                                 4

                                                                  Is direct                  Call for medical
                                Is patient
                                                          Y       medical              Y     supervision and
                               unstable on
                                                                supervision                initiate patient care
                                  scene?
                                                                availablea?                    as instructed

                                       N                               N
                                                                                              Coordinate with
                                                                                                                   5                               6
                                                                                            institutional or LGU
                                                                                           Command Center for           Coordinate with
                                                                                                          b                               c
                                                                                             destination and            receiving facility
                                                                                           ambulance/transport

                                                                                                                                                   7
                                                                                                                       Transport patient via
                                                                                                                          a COVID-ready
                                                                                                                        ambulance/vehicle
                                                                                                                       with IPCd measures
                                      FOOTNOTES

* Primary transport also known as pre-hospital transport: Transfer of a patient from
the site of an emergency (e.g., public place, residence or workplace) to a healthcare                                                          8
facility.                                                                                                                 See Figure G4
                                                                                                                          Management
a                                                                                                                            of COVID
  Medical supervision may be thru the patient’s primary care physician or a formal
institutional medical director who gives instructions for initial patient care while                                     Patient in transit
waiting and preparing for the medical transport to a health facility
b
 Receiving health facility equipped with appropriate resources, specialties, capacity
and availability to receive and treat patient.
c
  Confirm that receiving facility is ready for patient's arrival and patient's transfer
location. Communicate patient updates and management steps taken to facilitate
event-free transport. Provide estimated time of arrival (ETA) for ambulance at sending
facility.
d
  Satisfy following criteria: (1.) Isolate the ambulance driver from the patient
compartment and keep pass-through doors and windows tightly shut; (2.) Use vehicles
that have isolated driver and patient compartments that can provide separate
ventilation to each area.(3.) If 1 and 2 are not met, all windows are kept open to
ensure adequate airflow.
Figure G3 – Secondary Transport (Inter-Facility Transport) *

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                                                                1

                                       Patient for
                                      transport to
                                   appropriate facility

                                                            2

                                        Is patient
                                         clinically                 Y
                                        stable for
                                                  a
                                       transport ?

                                               N                3                                4                              5                           6
                                        Continue
                                     management at                        Coordinate with                              c                     e
                                                                                                         Communicate with            Arrange patient
                                   current facility until               institutional or LGU                                d
                                                                                                          receiving facility             transport
                                    patient stabilizes                   Command Centerb
                                   (See Fig C2 and D2)

                                                                                                                                                            7

                                                       FOOTNOTES                                                                    Transport patient to
                                                                                                                                       a COVID-ready
*Secondary transport also known as inter-facility transfer is any transfer, after initial assessment and                            ambulance with IPCf
stabilization, from and to a health care facility (Level 1, 2 or 3 non-COVID hospitals to COVID-19 hospitals, TTMF                       measures
and LIGTAS centers).
a Reassess patient if clinically stable and safe for transport. Transport only clinically stable patient with stable vital                                 8
signs. This also includes transport of stable high risk patients who require advanced airway but secured
                                                                                                                                    Healthcare worker
(intubated, on ventilator) and patients on vasoactive medication drips.
                                                                                                                                      team endorse
                                                                                                                                        patient to
b Coordinate with One COVID Referral Center or local government unit Emergency Operations Centers                                   transporting team

                                                                                                                                                            9
c
  Confirm that receiving facility is ready for patient's arrival and patient's transfer location. Communicate patient
updates and management steps taken to facilitate event-free transport. Provide estimated time of arrival (ETA)
for ambulance at sending facility.                                                                                                   Transporting team
                                                                                                                                      receives patient
d
 Receiving health facility equipped with appropriate resources, specialties, capacity and availability to receive
and treat patient.

e                                                                                                                                                          10
  Ensure that destination facility can be reached timely and safely. Communicate directly with an accepting                            See Figure G4
provider and check that patient's needs match the available services in the destination facilities:                                    Management
(a.) Admit Moderate (>60 years old) to Severe Suspect, Probable or Confirmed COVID-19 to Level 3 COVID                                    of COVID
Hospital. Admit Moderate (
Figure G4 – Management of Patient in Transit
                       1

    Patient for
            a
                                                                                        Return to Navigation
  transport to
appropriate facility                                                                                                                             FOOTNOTES

                                                                                   a All patients transported by an appropriate transport vehicle (Advanced Life Support or Basic Life Support that is either
                       2                                                           institution or LGU-based) accompanied by a team of healthcare workers from residence or any referring point of care to a
                                                                                   designated facility and vice versa.
 Check own safety                                                                  b
                                                                                     Re-assess every 15 minute for initially stable patients; every 5 minutes for severe/critical patients. If no pulse and no breathing,
 See Figure J1 for                                                                 follow BLS/ACLS Protocols with medical supeervision.
    proper PPE
                                                                                   C
                                                                                     The ABCDE (Airway, Breathing, Circulation, Disability, Exposure) approach also known as Primary Survey is a systematic way of
                                                                                   assessing a patient for emergency conditions; this is to ensure that life-threatening conditions are recognized early. The ABCDE
                           3                                                       approach ensures rapid assessment of the patient’s condition and that critical interventions are first done before transport
          b                                                                        d
 Re-assess with                                                                     If conversant, airway is patent. If altered mentation, may not be able to protect the airway and may be at risk for choking or
                                                                                   obstructing airway. Presence of snoring, stridor (high-pitched wheezing sound)
ABCDE c approach
 (Primary Survey)                                                                  e
                                                                                      Jaw thrust technique if trauma is suspected. Provide mask; If choking, do Heimlich maneuver; Suction secretions with viral
                                                                                   filter. Put oropharyngeal airway if without gag reflex.

                       4                                                           f
                                                                                     Look for signs of difficulty in breathing or cyanosis. Look, listen and feel to see if the patient is breathing. Assess if the breathing
                                                                                   is very fast, very slow or very shallow. Look for increased work of breathing - accessory muscle work, chest indrawing, nasal
      Is the                                                                       flaring, abnormal chest wall movement. Listen for abnormal breath sounds. Check for oxygen saturation if available.
     AIRWAY
                       Y
           d                                                                       g
     patent ?                                                                       Give oxygen titrated accordingly if warranted 92%
           N           5                             6                             h
                                                                                     Look, listen and feel for signs of poor perfusion/shock : cool, moist extremities, delayed capillary refill (CRT>2 secs);
                                                                                   diaphoresis; low blood pressure, increased work of breathing, increased heart rate; or faint/absent pulses. Look for
Open airway using                                                                  external active bleeding.
                                  Is the patient         Y
 head-tilt chin-lift
                                   BREATHING                                       i
  maneuver if no                              f                                     Start IV line if not yet inserted. Provide IV crystalloid at 10cc/kg then reassess, or start intravenous hydration with direct medical
                                    normally?
history of traumae                                                                 supervision. If you cannot start an IV line, consider nasogastric tube or Intraosseous line. Warm the patient. Stop external
                                                                                   bleeding (if present) with direct pressure.
                                          N              7                         j
                                                                                    Check for altered mental state using AVPU or GCS scale : check general response to stimulus if Alert, responds to Verbal
                                                                                   stimulus, responds to Painful stimulus or Unresponsive and check eyes, motor and verbal response using Glasgow Coma Scale.
                               Provide oxygenation                                 Check pupil. Check motor strength and sensation. Check capillary blood glucose.
                                 and ventilation g
                                                                                   k
                                                                                    Hypoglycemia with CBG of < 80 mg/dl or with altered mental status, Call for Direct Medical Supervision to give glucose : 50-
                                                                                   100 ml (1-2 amps) of D50water then recheck for improvement of sensorium and glucose level. Hyperglycemia: Call for Direct
                                                                                   Medical Supervision If entertaining Diabetic Ketoacidosis, treat with IV fluid hydration. Start at 2 liters of crystalloid solution for
                                                     8                             adults and 20cc/kg hydration for pediatrics. If extremely ill, transfer with no delay to a facility with intensive care facility. Fever
                                   Is the airway                                   with Altered Sensorium: Call for Direct Medical Oversight (EMS)/Supervision, give with Paracetamol.
                                  and breathing          Y                                                                     l
                                                                                                                                Examine the entire body for hidden injuries, rashes, bites, lesions. Respect the
                                       status
                                                                                                                               patient’s modesty. Remove constricting clothing/jewelry. Check for temperature.
                                    improved?
                                                                                                                               Cover the patient to prevent hypothermia; spray with cool water mist, fan and give IV
                                                                                                                               fluids for severe hyperthermia.
                                         N           9                             10
                                                                                                                               m
                                                               Does the patient                                                   SAMPLE history is the mnemonic used for targeted history-taking for Signs and
                               See Algorithm F2.2               have adequate          Y                                       Symptoms, Allergies, Medications, Last meal/oral intake and Events surrounding
                                    for ARDS                  CIRCULATION and                                                  injury/illness. Secondary Survey is the head-to-foot assessment or physical examination
                                                                          h                                                    of the patient and to be initiated only when all life-threatening conditions in the
                                                                 perfusion ?
                                                                                                                               Primary Survey are addressed. Reevaluation should be done every 15 minutes and
                                                                                                                               emergency interventions in transit should be seamless with continuous coordination
                                                                           N           11                           12         with the medical oversight until arrival at the appropriate receiving facility for handover.
                                                             Provide appropriate                 Does the patient
                                                               circulation and                     have intact
                                                                  perfusion                      DISABILITY and
                                                                             i                                  j
                                                                management                       mental status?

                                                                                                           N           13                                  14                                 15                                16
                                                                                                                                     Assessment of
                                                                                               Provide appropriate                                                   Set SAMPLE history                    Handover to
                                                                                                                                              l
                                                                                                              k                     EXPOSURE and                         and perform                   appropriate receiving
                                                                                                    Disability
                                                                                                                                    thermoregulate                    Secondary Survey                       facility
                                                                                                  Management
                                                                                                                                        properly

                                                                                                                                                                                                                                17
                                                                                                                                                                                                        Return to navigation
                                                                                                                                                                                                          table for further
                                                                                                                                                                                                          Management.
Figure G5 – Infection Prevention and Control for Ambulance EMS Team

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                                     1

             HCW to accompany
                patient for
                transport

                                    2                                 3                       4                           5                                6
                                                                                   Does the             EMS team
               Does the vehicle           Keep pass-through doors                 passenger            member with
               have a separate       Y    and windows tightly shut                                Y                            Y    Stay in the Driver’s
                                                                                compartment             NO direct
                   patient                  and provide separate                   have IPC               patient                     Compartment
                compartment?               ventilation to each area               measure?               contact?

                        N            7                                                 N                        N              8                           9

              Keep all windows
                                                                                                      Wear appropriate
               open to ensure                                                                                                          Level 3a PPE
              adequate airflow?                                                                             PPE

                                                                                                                                                           11
                                                                                                                              10
                                                                                                                                       Follow proper
                                                                                                      See Figure J1 PPE              donning, doffing,
                                                                                                                                   cleaning and disposal
                                                                                                                                           of PPE

                                                                                                                                                           12
                                     FOOTNOTES
a                                                                                                                                   Observe frequent
 Fit Tested N95 or any equivalent filtering face-piece respirator, water impermeable
gown, double gloves, dedicated shoes, shoe covers and goggles or face shield                                                        and proper hand-
                                                                                                                                        hygiene
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