Understanding asthma Oxford | Self-help guide - Oxford
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Oxford Living with asthma Years ago, asthma was a debilitating condition that in many cases seriously limited what a person could do. Fortunately — as a result of greater knowledge about asthma and its treatment options — the ability to manage this disease has vastly improved over the years. With proper care, today people with asthma live quite normal, active lives. In fact, life with asthma at times can even be extraordinary for Olympic gold medalists or professional athletes who break records — despite their asthma. When you manage your asthma, you can do almost anything you want to do. Throughout this book, you’ll learn how to keep your asthma under control so that you too can continue to lead a healthy, fulfilling life. Asthma can be different for everyone who has it. What triggers it for one person may not for another. This guide is not a substitute for medical advice from your physician. Your health care provider can help you develop your own asthma action plan. Bring this book along to your next doctor visit and ask your health care provider to help you complete your personalized asthma action plan on pages 25 through 27. Before long, you can be on the road to successfully managing your asthma. The word “asthma” is derived from a Greek word meaning “breathlessness” or “panting,” both of which describe symptoms present during an asthma attack 2
Oxford Contents 1. Understanding asthma 5. Taking action when asthma acts up What is asthma?............................................ 2 Heeding the warning signs..................................23 How is asthma diagnosed?............................. 2 Signs of poorly controlled asthma........................24 The asthma spectrum..................................... 3 Get control with an asthma action plan...............24 Why me?........................................................ 3 6. Asthma and exercise 2. Tracking asthma triggers What is exercise-induced asthma?.......................28 Allergens........................................................ 4 Pretreatment for exercise-induced asthma...........29 Infections....................................................... 6 Enhancing your performance...............................30 Irritants.......................................................... 6 Exercise.......................................................... 7 7. S pecial concerns for children and teens Aspirin and other Asthma and school...............................................31 anti-inflammatory medications................... 7 Asthma and teens................................................32 Emotions....................................................... 8 Using what you know about triggers.............. 9 8. Other things to consider Asthma and pregnancy........................................33 3. Monitoring your asthma Asthma and other medical conditions..................33 Using a peak flow meter............................... 10 Asthma and emotions..........................................34 If your child has asthma............................... 12 Tips for traveling.................................................34 Keeping an asthma diary.............................. 12 9. Getting additional help 4. Getting the most from asthma medications Medical professionals...........................................35 How asthma medications work.................... 13 Organizations......................................................35 Long-term control medications................... 13 Additional reading...............................................36 Quick-relief medications............................. 15 Other medications....................................... 17 Administering asthma medications.............. 18 10. Glossary and appendix...............................37 Asthma medications...............................20-22 1
Oxford 1. Understanding asthma When you breathe, air moves through your nose or mouth down to your windpipe (trachea). Just as the windpipe meets the lungs, it branches off into two large airways (bronchi), one to each lung. Within the lungs, the large airways branch off into smaller airways (bronchioles) leading to many small air sacs (alveoli). These air sacs do two very important jobs. First, they transport oxygen from the air you breathe into your bloodstream. Second, they remove carbon dioxide from your blood so it can be removed from your body when you exhale. What is asthma? Asthma interferes with normal breathing by narrowing Many people with asthma experience times when they the airways both within and leading to the lungs. When have more problems breathing and times when they the airways are narrowed, the amount of carbon dioxide feel perfectly normal. The times of greater difficulty are leaving the body and the amount of oxygen entering called “asthma episodes.” During an asthma episode, the body are both restricted. With asthma, one or more you may have sudden coughing or wheezing that can of the following situations cause the airways to narrow. cause you to feel short of breath. Asthma episodes can last from a few minutes to several hours or days. Tightening of the muscles that wrap around the airways. For people with asthma, the airways Fortunately, the airflow obstruction caused by asthma sometimes overreact to triggers. The result is can be reversed, often rapidly. This is one of the key spasms of the muscles encircling the airways, called ways in which asthma is different from other diseases, bronchospasm. As these muscles contract or tighten, such as emphysema. Sometimes, bronchospasm will the space inside the airways narrows and less air is simply stop on its own. But more often, medications are able to pass in and out of the lungs. needed to prevent and treat asthma episodes. Although there is no cure for asthma, with the help of your health Inflammation of the airway linings. The same triggers care provider, you can learn to manage this disease so it that cause bronchospasm can also cause ongoing doesn’t interfere with your daily life. (chronic) swelling and inflammation in the inner lining of the airways. Like bronchospasm, inflammation of How is asthma diagnosed? the lining narrows the space available for air to pass Asthma symptoms can be different from person to through. When the lining of the airways is irritated person. For some, the main symptom is a persistent and inflamed, bronchospasm is more likely to occur. cough. Others may experience wheezing, chest tightness, shortness of breath or any combination Twitchiness of the airways. The airways in a person of the above. with asthma narrow in response to triggers such as exercise or cold air. How easily this occurs is often Asthma tends to run in families (about 40 percent of referred to as twitchiness or bronchial hyperreactivity. children who have parents with asthma will develop asthma), and most people who have asthma develop Overproduction of mucus. Mucus normally coats their first symptoms while still young. About half of the airways and cleans away small particles of foreign those with asthma show symptoms before age 10, and matter, such as dust and dirt, from the air passages. most develop it before age 30. But anyone can develop When the airways become inflamed during an asthma asthma at any age. episode, too much mucus may be produced. The excess mucus takes up space in the airways, blocking the free Because other illnesses and diseases can cause similar flow of air. It may also become dry and sticky, further symptoms and difficult breathing, you should see obstructing the airways. As a result, it is more difficult your health care provider to determine whether the to clear away the mucus by coughing, and bacteria can problem is asthma or something else. Be prepared to grow in the mucus, resulting in bronchitis. give specific information about when and under what circumstances your symptoms tend to occur. 2
Oxford For example, your health care provider will probably periods when your asthma flares frequently; at other ask you some of the following questions: times in your life, you may have few problems. }} What symptoms are you having (wheezing, If you are the parent of a child who has asthma, keep in coughing with mucus, chest tightness, shortness mind that about half of all children with asthma “grow of breath)? out” of the disease and have lessening symptoms by the time they are 15 years old. Some of these individuals, }} When do these symptoms usually occur (during however, may develop symptoms again later in life. the day or night, at home or at work, after exercise, only during certain seasons of the year or certain The key to managing asthma is understanding your weather conditions)? symptoms and learning what triggers and relieves them. These topics will be discussed further in the }} How often do you have problems (occasionally, next chapters. daily, a few times a month, only after a cold or other upper-respiratory illness)? Why me? }} Do you have any known allergies? Many people think asthma is a disabling disease — Your answers to these kinds of questions will help your something that makes you unable to participate in doctor develop a history of the problem. This history, sports, be active or enjoy life. Though asthma has had together with a physical examination, will help your this reputation in past years, it just isn’t true today. With doctor decide if further tests are needed. These may medications, asthma can be controlled so it doesn’t include chest x-rays and spirometry. The x-rays help interfere with leading a normal, active lifestyle. rule out other possible causes for your symptoms. If no This is not to say it will be easy for you to adjust to other lung disease is present, chest x-rays will be fairly having asthma and to the things you need to do to take normal in a person who has asthma. care of it. Learning that you have a chronic disease such Spirometry is a test that involves blowing into a device as asthma can raise a variety of emotions — some not called a spirometer. The spirometer measures the so pleasant. You may feel angry, frustrated or worried amount and speed of air that is breathed out, indicating about what your future will be like living with asthma. how open or narrow the air passages are. When the You may wonder why this had to happen to you. passages narrow during an asthma episode, the force of Just remember that all these feelings are perfectly exhaled air measured by the spirometer is lower than normal. These feelings usually pass as time goes by normal. Some people who have asthma, however, may and you become more comfortable and confident have normal spirometry results during times when they that you really can manage this disease and prevent are symptom-free. This is one way your health care and treat asthma episodes. If you continue to struggle provider can tell that the problem is asthma and not with feelings of frustration, anger, worry or fear, or if emphysema or chronic bronchitis, both of which are these feelings are interfering with your daily life or diseases that cause irreversible damage to the lungs. relationships, talk with your health care provider. He or she may be able to recommend a counselor or other The asthma spectrum mental health professional who can help you. Asthma can range from very mild and intermittent to Family, friends, co-workers, teachers and coaches severe and persistent, with a wide spectrum in between. can also provide valuable support if they understand Your grade of asthma depends on your daytime and asthma. Share what you know about asthma with the nighttime symptoms, and your breathing test results. people who care about you, and let them know how Each level of asthma requires a different approach to they can help you if you have an asthma episode. You treatment. The severity of your asthma can change over might even want to lend them a copy of this guide. time, depending on how your body reacts to different triggers at different times in your life. You may have 3
Oxford 2. Tracking asthma triggers Most people don’t regularly pay attention to the way their bodies react to things around them. Becoming aware of your body’s response to different environments and materials, however, can be an important strategy for managing your asthma. For most people, asthma episodes are regularly triggered by one or more factors — allergens, infections, irritants, weather conditions, exercise, emotions or even aspirin products. What causes an asthma episode in one person, however, may not bother another person who has asthma. The first step in managing your asthma is identifying your asthma triggers and finding ways to avoid them as much as possible. Allergens people, the allergic reaction to specific allergens is an Your immune system is designed to protect your body asthma episode. from harmful intruders such as bacteria and viruses. Asthma and allergies often go hand-in-hand, but When one of these intruders, or antigens, enters the having one of these conditions does not necessarily body, the immune system kicks in by releasing special mean you have or will develop the other. (Although chemicals to combat the invaders. an estimated 95 to 98 percent of children with asthma }} What triggers asthma for one person may have nasal allergies, only 40 to 50 percent of adults not for another with asthma have nasal allergies.) If you do have both, }} Those who live in the inner city have an increased however, your allergies may be triggering your asthma. risk for developing asthma (Source: National Allergies that trigger asthma Institute of Allergy and Infectious Diseases) The first clue that you may have an allergy is if you }} Asthma tends to flare most often at night, in the regularly experience allergy-like symptoms in specific early morning hours or after exposure to a trigger situations. For example, maybe you have allergy symptoms only at certain times of the year or when you If you have a bacterial or viral infection, these may visit a home where a cat or dog lives. Maybe you have cause your body temperature to rise or your nose to run year-round symptoms, indicating that you might be as a way of ridding the antigen from the body. allergic to something in your home, such as dust mites In some people, the immune system can also react or molds. when the body is exposed to certain antigens, such as Allergies can develop slowly with repeated exposure dust mites or pollen, that are not normally harmful to an allergen over time. For example, a person who to the body. These antigens are called allergens, and grew up on a maple-lined street may be well into the immune system’s overreaction is called an allergy. adulthood before developing an allergy to maple pollen. Allergic reactions affect specific areas of the body: Even though they may have taken months or years }} The skin — with rashes, itching, eczema or hives to develop, allergies may seem to pop up overnight. }} The nose — with runny nose, congestion Common allergens to consider as you search for your or sneezing asthma triggers include the following: }} The eyes — making them itch, swell }} Animal and insect allergens. Cats, though perhaps or become watery the most frequent culprits, aren’t the only sources of animal allergens. Dogs, horses, guinea pigs, }} The airways — causing asthma birds — just about any furry or feathered friend — Different allergens cause different allergic reactions in may also trigger allergic reactions in some people. different people with allergies. A food allergen, such as Allergens may be found in animal dander (similar eggs or peanuts, may cause a person with that specific to dandruff ), saliva or urine. Reptiles and fish are allergy to break out in hives. On the other hand, an about the safest pets for people prone to animal airborne allergen, such as animal dander, pollen, mold allergies. In addition to pets, household pests such or dust, may cause a runny nose or itchy eyes. For some as cockroaches may serve as allergens. 4
Oxford }} Seasonal allergens. These primarily include pollens. Tree pollens are most abundant during the Reducing allergens in your home spring, grasses in the spring and summer, and weed Here are a few things you can do pollens, such as ragweed, in late summer and fall. Seasonal allergens vary with geographic regions. }} Household allergens. Dust mites (microscopic }} Encase the mattress and pillows in allergen-free insects found in household dust) and fungi covers to help reduce dust and dust mites in the (mold and mildew) can cause year-round allergy bedding; some mattress encasings are made symptoms. Dust mites and fungi especially like to with microfiber fabric to prevent excess heat breed in damp places and humid environments, and moisture such as the bathroom, basement and kitchen. }} Opt for bare floors or easy-to-clean area or throw Warm, humid weather can also contribute to rugs instead of wall-to-wall carpeting higher household allergen levels. }} Keep pets out of the bedroom at all times (if If you think you may have allergies, talk with your possible, keep pets out of all living areas of health care provider. He or she may recommend your home) that you see an allergist (a doctor specializing in }} Dust and vacuum regularly allergies) for allergy testing. During an allergy test, }} Don’t use feather pillows or genuine very small amounts of allergens are placed on (a down comforters “scratch test”) or injected under your skin. If your skin reacts with redness or a raised, itchy bump }} Take a quick shower before bed to rinse off any where the allergen was placed, you are allergic to pollens or mold spores on your body and prevent that allergen. prolonged exposure to allergens while sleeping Treating allergies to manage asthma }} If you don’t have central air conditioning, install a Once you know what, if anything, you are allergic window air conditioner during the warm seasons to, you can use an asthma diary to see if your asthma to avoid the need for open windows (which allows episodes seem to be connected with your allergies, as more pollen in from outdoors) and to help reduce identified by skin testing. If they are, the first and most humidity; if you have central air conditioning, keep important step for controlling both your allergies and windows closed to help prevent pollens and mold your asthma is to find ways to avoid those things to spores from entering the house; air conditioning which you are allergic. lowers indoor humidity levels, which decreases the mite population Avoiding allergens isn’t always easy. Your health care }} Avoid hanging clothes to dry outside, where they can provider can give you more information on how to be exposed to pollens and mold minimize your exposure to specific allergens. You may find some suggestions very practical and others nearly }} Take precautions in your basement, which impossible given your personal circumstances. tends to have higher humidity levels; avoid putting carpeting on a cement slab floor and having If you can’t make your entire house “allergen-free” (keep bedrooms in basements in mind that no home is ever entirely free of allergens), }} Don’t use humidifiers or vaporizers in the bedroom; focus your efforts on the bedroom, which is the most they provide an optimal environment for molds and important room of the house because you spend six to dust mites 10 hours a day there. 5
Oxford For many people with allergies, medications provide Viral infections can also cause a cough. But because important prevention and relief of symptoms. If coughing can also be a symptom of an asthma your asthma is triggered by allergies, taking your episode, you don’t want to mask the asthma by using allergy medications as directed can help prevent a strong cough suppressant. If you need relief from or reduce the severity of asthma episodes. In some a nagging cough, you may use an over-the-counter cases, immunotherapy or “allergy shots” are used to cough medicine containing dextromethorphan, but be desensitize the immune system to certain allergens. sure you are also taking your asthma medications as prescribed. Drinking lots of clear liquids (water and Infections juices) is the best medicine for loosening mucus in the Bacterial and viral infections are another common airways so it is easier to cough up and clear away. asthma trigger. Viral infections, such as colds and flu, tend to trigger asthma episodes more frequently If colds or flu tend to trigger your asthma, your health than bacterial infections, such as strep throat or sinus care provider can recommend asthma medications to infections. Though these types of infections mostly begin taking early during the viral infection to help affect the upper airways in the nose, throat and sinuses, prevent an asthma episode. Call your health care the lower airways may also become irritated if you provider for advice if cold symptoms: have asthma. }} Worsen after three to five days For some people, their first asthma episode comes }} Don’t improve and remain bothersome after during or shortly after having bronchitis or pneumonia. seven days While these asthma episodes can last several weeks or even months, they may not occur again. Some people, }} Are not resolved after 14 days however, may develop ongoing asthma problems. You should also call for advice if your asthma flares up with the cold or if you are coughing up colored mucus Avoiding trigger infections from your chest. For colds in children, call for advice if }} Keep healthy with nourishing foods, lots of fluids, fever persists and cold symptoms are very bothersome regular exercise and plenty of sleep after three days. }} It may be impossible to prevent getting a cold, flu Irritants or other upper-respiratory infection entirely Asthma symptoms are aggravated by many factors, }} Avoid close contact with those who have colds or both outdoors and indoors. These irritants are different flu, especially during the first few days of illness from allergens because they do not trigger the body’s }} Wash your hands regularly immune system as allergens do — they simply irritate }} Ask your doctor if you should get a flu shot in the airways. the fall of each year; remember that flu Examples of irritants include: immunizations provide protection against the strains of influenza present that year only and }} Smoke from tobacco or wood must be repeated each fall }} Various dirt particles in the air Viral infections generally must take their own }} Extremes or sudden changes in weather, including course. Antibiotics have no effect on viruses. Using a temperature, barometric pressure, or humidity decongestant, however, may help relieve stuffiness and }} Air pollution congestions that can irritate your asthma. }} Fresh flowers }} Fumes and fragrances from a variety of products 6
Oxford Avoiding irritants The most common activities that can cause an asthma You will probably find that some of these irritants episode are aerobic activities, such as jogging or trigger your asthma, while others do not. You’ll also cross-country skiing, which involve continuous notice that some are easier to avoid than others. movement sustained over a long period. During those As with allergens, you can use an asthma diary to kinds of activities, air is breathed in through the mouth. help you identify which irritants, if any, tend to This air is colder and drier when it reaches the lungs trigger your asthma. than air that is inhaled through the nose. In those with exercise-induced asthma, the colder, drier air acts as an Tobacco smoke is a particular concern, especially in irritant to the lower airways, causing them to spasm. homes with children who have asthma. Studies have shown that very young children who live in homes Not all sports or exercise involve this kind of where someone smokes are more likely to develop continuous, sustained movement. Football, baseball and asthma and to have asthma episodes that require tennis are examples of sports involving shorter sprints. emergency room care. School-age children also have Brisk walking can provide aerobic exercise without more school absences if parents or other members of the need to breathe through the mouth. Swimming is the household smoke. In addition, smokers themselves often recommended as one of the best aerobic activities are known to develop more frequent upper-respiratory for people who have asthma. Though it does involve infections. breathing through the mouth, the surrounding water tends to humidify the air, making swimming less likely Make your home off-limits to smoking. When than other activities to trigger asthma. reserving a hotel room, request a non-smoking room. If you choose to jog or participate in activities that can Cold air may irritate the lungs of some people with trigger your asthma, ask your health care provider to asthma. Short of packing up and moving to Arizona, recommend pretreatment medications to avoid asthma those with asthma can prepare for fluctuations in the episodes, then allow yourself an adequate warm-up period. weather by dressing appropriately. In very cold or windy weather, wear a scarf or face mask over your mouth to Pay attention to your body’s reactions to exercise. ward off cold blasts. Exercise-induced asthma can occur either during or after exercise. Be sure to have appropriate medications Outdoor air pollution is an irritant you can’t totally available in case you have an asthma episode. avoid, but you can lessen its impact by rolling up your car windows or closing up the house and turning on the Aspirin and other anti-inflammatory medications air conditioning. Watch the weather reports, and avoid }} Aspirin and other nonsteroidal anti-inflammatory strenuous outdoor activities on days when the pollution drugs (NSAIDs) act as triggers in a small level is high. percentage of people with asthma. Because aspirin- induced asthma episodes can be severe and come Exercise on very quickly, you should avoid taking aspirin and In years past, exercise-induced asthma led people to other NSAIDs if you have aspirin-sensitive asthma. believe that those with asthma could not participate in sports or physical activities. We now know that by }} Ibuprofen (Advil®, Motrin®, Nuprin®) and carefully choosing activities and using pretreatment naproxen (Aleve®) are other NSAIDs that are medications when needed, people who have asthma can available without prescription. A variety of other be just as physically active as anyone else. over-the-counter medications contain aspirin. Read labels carefully, or ask your pharmacist before taking any non-prescription medication, especially pain relievers and cold remedies. Choose products containing acetaminophen (Tylenol®) for treating fever or pain, such as headaches. 7
Oxford Emotions }}Technique 1: Quieting response Excitement, stress, fear and other emotions — even 1. Sit comfortably. laughter — are said to trigger asthma episodes in some (You can also learn to do this while people. In reality, however, the emotions themselves are standing, such as waiting in line, or just not the direct trigger; rather, the asthma episodes occur before an anticipated stressful event.) as a result of more rapid or heavier breathing brought on by crying, laughing or feeling anxious. So even when 2. Draw in a deep breath through your nose, emotions are involved, asthma is still a physical disease. and hold it for five seconds (count to five slowly). Exhale slowly through your mouth, Stress management techniques and tell all your muscles to relax. Repeat this Practicing stress management techniques can be an two or three times to become more com- effective way of reducing asthma episodes triggered pletely relaxed. by emotional upset. Both techniques involve deep 3. If circumstances permit, imagine a pleasant diaphragmatic breathing (breathing from the thought (“I’m able to relax and let go diaphragm, so your abdomen — not your chest — throughout the day”) or a pleasant scene (a moves in and out). calm lake or a mountain stream). In addition to promoting relaxation, these techniques e quieting response technique takes from Th are useful during asthma episodes to help you get more 30 to 60 seconds. air while waiting for medications to begin working. You will be able to use these techniques best during asthma }}Technique 2: Deep breathing episodes or times of emotional upset if you practice them regularly during non-stressful times. 1. Choose a quiet spot, and get comfortable. Relaxation techniques 2. Gently blow out all the air in your lungs. Here are some specific techniques that can aid in 3. Slowly count to eight while inhaling through relaxation and stress management. The more you your nose (count “1-and-2-and-3-and,” practice these relaxation techniques, the more they can to eight). Then hold your breath, again to help reduce asthma episodes. the count of eight. Finally, slowly exhale through your mouth while counting to eight. Daily practice, especially at first, will help make these relaxation techniques become second nature for you. 4. Resume slow, rhythmic breathing for a few When this happens, it will be even easier for you to use minutes. The in-and-out cycles should be the techniques when you need them most — during an equal in length. Go deeper than shallow, asthma episode or when you are under a lot of stress. upper-chest breathing. If you are breathing Parents can coach their children through these exercises as you should from your diaphragm, your and encourage them to use them if they feel an asthma chest should barely move, but your abdomen will expand and contract. episode beginning. 5. Repeat the whole process again. A written asthma management plan can also offer reassurance and confidence for people with asthma. Sometimes, fear can intensify an asthma episode. Just knowing that you can effectively treat the episode and continue to breathe can help prevent an episode from worsening because of fear. 8
Oxford Using what you know about triggers Managing asthma triggers is the most effective approach for preventing asthma episodes. Once you know what triggers your asthma, you can begin to find ways to avoid triggers. Asthma trigger checklist Think about what triggers your asthma. Put a check mark next to the items that affect you. Allergic triggers __ House dust (dust mites) __ Animals __ cats __ Seasonal allergens — pollens from trees, grass, __ dogs ragweed or other plants __ rodents (hamsters, guinea pigs) __ birds __ Mold outdoors, mildew indoors __ Other Irritants __ Tobacco smoke __ Outdoor pollution (smog, car or truck exhaust, etc.) __ Weather conditions — extremes or sudden changes in temperature, barometric pressure __ Fragrances or fumes from various products: or humidity _________________________________________ __ Air pollution _________________________________________ __ Indoor pollution (smoke from fireplaces or wood-burning stoves; fumes from building products, carpeting, paint; etc.) Infections __ Viral upper-respiratory infections — colds __ Bacterial infections — strep throat, sinus and flu infections, pneumonia or bronchitis Exercise of physical exertion __ Specific sports or other activities: _______________________________________________________ _______________________________________________________________________________________ Emotions __ Crying or laughing __ Anger __ Stress __ Fear (especially when an asthma episode begins) Infections __ Aspirin __ Ibuprofen (Advil ®, Motrin®, Nuprin®) __ Other NSAIDS __ Naproxen (Aleve®) 9
Oxford 3. Monitoring your asthma The goal for those with asthma should be to live like everyone else, without asthma getting in the way of life’s wonderful possibilities. A good asthma management plan should be able to reduce the severity and frequency of asthma symptoms, as well as prevent unscheduled visits to the doctor or hospital. Your health care provider can teach you asthma self-care techniques. Work with him or her to develop a management plan that’s best for you. You will Just as fingerprints are different from person know your plan is working if it helps you achieve to person, so is asthma; your symptoms the following asthma-management goals: and treatment plan may be different from someone else’s }} Reduce the severity and frequency of asthma symptoms Asthma episodes range from mild to severe }} Alleviate nighttime awakenings and can last from a few minutes to a few days }} Allow for fuller activity }} Prevent unscheduled visits to the doctor or hospital When your asthma is well controlled, you can live a healthy and active life Most asthma management plans include the following elements: }} Watching for early warning signs by monitoring symptoms or using a peak flow meter to measure Using a peak flow meter lung function A peak flow meter is a good tool for assessing and }} An asthma diary to record peak flow readings, monitoring asthma. This inexpensive, hand-held device asthma episodes and circumstances surrounding measures the maximum or “peak” speed at which air asthma episodes can be exhaled from the lungs. During an asthma }} Appropriate medications for preventing and episode, the peak flow is slowed because the airways are controlling asthma episodes constricted and partially blocked. }} Guidelines for when to call a health care provider As early as 24 hours before asthma symptoms appear, Your health care provider will teach you how and your breathing capacity may already begin to drop. The when to take medications and help you identify your peak flow meter can detect this drop so that you can asthma triggers and ways to avoid them. By reading start taking appropriate medications before wheezing this guide, you’re already off to a good start. Learning or coughing even begins. But not everyone who has self-care techniques, including when and how to use asthma needs to use a peak flow meter. Some people are medications, puts you in control of your asthma. very good at recognizing early signs of asthma episodes and treating them appropriately. Early detection of an asthma episode can also make it easier to identify your asthma triggers. For example, a weather change or a visit to a home with a pet on Saturday afternoon may be the trigger behind an asthma episode but if you don’t notice any asthma symptoms until Sunday, it may be more difficult to 10
Oxford draw the connection between the cat or the weather change and your asthma. A routine peak flow Steps for using the peak flow meter measurement taken on Saturday, however, may make it easier to identify the real trigger. Peak flow meters can help you recognize triggers that otherwise might be 1. Move the pointer to the base of the overlooked. numbered scale. Even some children as young as three years old can 2. Hold the peak flow meter, being careful not learn to use a peak flow meter. Your health care to block either the mouthpiece or the air exit. provider may initially recommend that you take a peak 3. Stand up. flow meter reading two or more times a day. Usually the 4. Take a deep breath. readings are taken right after waking up in the morning 5. Place the meter in your mouth, closing your and again before going to bed. You may also be asked lips gently around the mouthpiece. to take a breath before and after taking inhaled medications. Your doctor can help you determine the 6. Blow out as hard and fast as possible. best testing times for you. (The device measures the maximum speed of your expiration, not how much air Peak flow zones you exhale. A short and fast blow gives the Peak flow readings are divided into three zones — best reading.) green, yellow and red — like a traffic light. Readings 7. W rite down the number indicated by the in the green zone mean you are doing fine, while pointer. readings in the yellow zone mean your asthma is not 1 . Repeat steps 1 through 7 two more times well controlled and you should take medications as (unless the test has provoked a coughing prescribed in your asthma action plan. Readings in the attack). red zone mean a severe asthma episode is under way 2. R ecord the highest of the three numbers and you should call your health care provider or seek achieved. This is your peak flow reading. immediate medical attention. The exact ranges of these zones vary from person to person. Height and age are factors, and the best possible peak flow readings vary somewhat between men and women and among different ethnic groups. Your health care provider will help you determine your “personal best” peak flow and then use this number to establish the three zones of your asthma action plan. Green (all clear) represents 80-100 percent of your personal best reading; yellow (caution) indicates 50-80 percent of your personal best; and red (danger) shows below 50 percent of your personal best. Once these zones are established, your doctor can recommend an asthma action plan specially tailored to your needs. Asthma action plans will be discussed in detail in Chapter 5. 11
Oxford If your child has asthma Keeping an asthma diary Children, too, can be involved in their own asthma care, One of the most important steps in managing learning to watch for early symptoms and taking their persistent asthma is to keep a daily written record, own peak flow meter readings. However, until your or asthma diary, that shows peak flow meter readings, child is old enough to accurately keep an asthma diary medications taken, asthma symptoms and and follow an asthma action plan unassisted, you will possible triggers. need to take special care in monitoring, treating, and recording symptoms and peak flow readings. By keeping a daily written record of your symptoms and peak flow readings, you can begin treatment earlier In addition to the common warning signs described and reduce the number and severity of asthma episodes. in this chapter, watch for wheezing during the night. Your doctor may also use the information recorded in Increased amounts of mucus production in the airways your asthma diary along with peak flow readings taken may produce coughing and wheezing in a sleeping in the office to determine whether your medications are child. Your child may need to use his or her inhaler or doing the job. nebulizer during the night. When asthma is properly managed, however, there should be no nighttime The information you record in your asthma diary is asthma symptoms. important for developing an asthma action plan that meets your individual needs. An asthma diary can also Talk with your child’s teacher or daycare provider about help you identify possible asthma triggers you may not asthma. Let them know what symptoms to watch for. have been aware of before. Make sure the day care provider, teacher and the school health office have copies of your child’s asthma action Keep your asthma diary in a safe, accessible place, and plan. Also be sure your child has a separate supply of take it along on each visit to your health care provider. medications that is kept in a readily accessible place at A sample asthma diary is shown on page 40. school or daycare. 12
Oxford 4. G etting the most from asthma medications There is no “cure” for asthma. However, medications can prevent and control symptoms. Most people with asthma can lead normal, healthy lives. Each person’s asthma is unique. In the same way, ways to treat asthma must be targeted to each person’s needs. Some people with asthma take medicine daily. Asthma cannot be cured, but it can be Others take it only as needed. managed. Remissions (or periods with no symptoms) may occur. Asthma is classified by the severity of your symptoms and breathing test results. The most common is mild Most people with asthma need to be seen by intermittent asthma. Persistent asthma can be mild, their doctor at least once a year. moderate or severe. The type and amount of medicine is matched to the severity. The treatment first gains control of the asthma symptoms. Then it keeps control Some over-the-counter drugs can cause bad with the minimum effective dose. reactions if taken with asthma drugs. Check with your doctor or pharmacist before taking Learning about your medications will help you to use other drugs. them safely and effectively. You should know what they do and how they work. You should learn when to take them and any side effects. Taking them as directed is essential. Work with your health care provider to tailor Long-term control medications a program to your needs. The best way to control an asthma episode is to prevent it. Many types of medications are used for long-term How asthma medications work control. Anti-inflammatory drugs work to prevent Many medications are used for asthma. Your doctor mucus production and airway swelling. They do not prescribes for the severity of your asthma. Many with give fast relief of asthma symptoms. They do help mild intermittent asthma can manage well with a control asthma with regular use. To work, they must be quick-relief drug. Most people with frequent episodes taken daily — even on days when you feel fine. or persistent asthma take at least two drugs. One is for quick relief during an episode. It relaxes the muscles of the airways. The other is for long term control. It is taken daily to prevent inflammation and mucus production. You should know which medication is for which purpose. You must take your daily long-term medication to manage your asthma. But this will not give relief during an episode. For that, you need a quick-relief medication. 13
Oxford Inhaled corticosteroids Leukotriene modifiers Inhaled corticosteroids are the most potent and Leukotriene modifiers are another way to control effective long-term drug. They reduce swelling asthma. Leukotrienes cause tightening of the bronchi in the airways. They reduce asthma episodes and the and increase mucus. Zafirlukast (Accolate®) and need to go to the hospital. They increase breathing montelukast (Singulair®) are oral drugs that block test results. They reduce airway twitches. They may the actions of leukotrienes. They are used in adults prevent damage to the airways. Regular daily use is key. and children. They can be used alone or with inhaled It can take five to seven days before they begin to work. corticosteroids. There are many kinds and strengths. The dose may vary with the product used. Usually they are taken one to two times per day. One type of inhaled corticosteroid is a nebulized form. It is called budesonide. The brand name is Inhaled corticosteroids Pulmicort Respules®. It often helps children who have persistent asthma. Minor side effects from inhaled steroids may be • Beclomethasone dipropionate (QVAR®) hoarseness and thrush. Thrush is a yeast infection in • Budesonide (Pulmicort Turbuhaler®, the back of the throat and tongue. This can be reduced Pulmicort Respules®) by using a spacer with the inhaler. It also helps to • Flunisolide (AeroBid®, AeroBid-M®) rinse the mouth with water or gargle with mouthwash • Fluticasone propionate (Flovent®, Advair®) after use. Inhaled corticosteroids help many people reduce their need for oral corticosteroids. These can • Triamcinolone acetonide (Azmacort®) have more serious side effects, such as reduced growth, • Mometasone furoate (Asmanex) osteoporosis, cataracts and glaucoma. Long-acting beta agonists Long-acting beta agonists Long-acting beta agonists can be inhaled or oral. Inhaled salmeterol and formoterol fumarate (Foradil®) can help you breathe better for about 12 hours. They are usually used with an inhaled corticosteroid Inhaled for long-term control. Inhaled beta agonists are the • Formoterol fumarate (Foradil®) preferred type. They have fewer side effects. They last • Salmeterol (Serevent Diskus®) longer than sustained-release albuterol tablets. Oral Inhaled steroids combined with • Extended-release albuterol (many brands) long-acting beta agonists Advair is a combination of fluticasone propionate (Flovent®) and salmeterol (Serevent®). It comes in three strengths: 100/50, 250/50, 500/50. Symbicort is a combination of Budesonide and Formoterol. It is available in 160/4.5 and 80/4.5. Dulera is a combination of Monetasone and Formoterol. It comes in two strengths: 200/5, 100/5. 14
Oxford Cromolyn sodium and nedocromil Theophylline can interact with other drugs. Talk with (mast cell stabilizers) your doctor or pharmacist before taking any other Cromolyn sodium and nedocromil are called mast cell drugs — prescription or over-the-counter. Never adjust stabilizers. Cromolyn sodium (Intal®) is inhaled. It your dose on your own. Taking less than the prescribed keeps the airways from getting inflamed. It is used to dose or skipping doses can lead to an asthma episode. control mild to moderate allergic asthma. It is taken Taking more than the prescribed dose can lead to through an inhaler or nebulizer. It may be used all year serious side effects. These may include seizures. or only in some seasons. Anti-IgE therapy Cromolyn sodium also helps control asthma set off Anti-IgE therapy [with omalixumab (Xolair®)] has by exercise or cold air. For these cases, it is taken just been approved by the Food and Drug Administration. before exercise or exposure to cold air. This is an injection given every two to four weeks. It decreases the amount of allergic antibody. It has been Nedocromil (Tilade®) is a non-steroidal drug like shown to reduce asthma flares and the need for other cromolyn sodium. It is used with an inhaler for mild to drugs. It also reduces allergic rhinitis (hay fever). moderate persistent asthma. Both of these drugs can take two to six weeks of use before they begin to work. Quick-relief medications Epinephrine is often used in emergency rooms for Theophylline asthma attacks. (It is also called adrenalin.) It gives fast Theophylline is a methylxanthine drug that keeps relief by causing the airways to open, restoring a free airways in the lungs relaxed and open. It can take up flow of air. It is not recommended for regular use. to several hours to work. It is not used for treating It can increase the heart rate. It should only be given episodes that are already under way. It is used less often by a health care professional. than inhaled corticosteroids. Theophylline comes in a variety of forms and strengths. Capsules are a convenient form for young children. They can be opened and mixed with foods such as yogurt. Theophylline can produce side effects. These may include headache, nausea, vomiting, stomach cramps, diarrhea, insomnia, fast heartbeat and restlessness. These can be a sign that your dose is too high. If you have any of these, talk with your provider. He or she may use a blood test to check your level of theophylline. If it is too high, your doctor will adjust your dose or change the product. 15
Oxford Short-acting bronchodilators Other drugs called bronchodilators work much like Commonly prescribed epinephrine, but are safer. They also work by relaxing short-acting beta agonists the muscles to let the airways open up and make it easier to breathe. Albuterol (Proventil®, Ventolin®) Inhaled short-acting beta agonists are the most Levalbuterol (Xopenex®) common family of bronchodilators. They work fast and are easy to use. They have few side effects and can be Metaproterenol sulfate (Alupent®) targeted to the lungs. They are used to give fast relief Pirbuterol acetate (Maxair®) during an asthma episode. They come in tablets, syrups, metered-dose inhalers (MDIs) and nebulized solutions. When used with an inhaler, the beta agonist goes right into the airways to ease the spasm. Relief begins within Anticholinergics 5 to 15 minutes. It lasts for about 4 to 6 hours. Long- Anticholinergics are a type of cough suppressant. They lasting beta agonists are not “rescue” inhalers. They block signals in the nervous system that tell the body to should not be used for relief from an episode. cough. Ipratropium bromide (Atrovent®) is an inhaled medication. It offers fast relief from acute episodes. It MDIs can be carried in a pocket or purse for use when is most often used with a beta agonist to relieve coughs coughing or wheezing starts. Beta agonists in syrup, or for dilation of the bronchi. It begins to work within tablet and nebulizer forms can be used with young 30 minutes after it is taken. Combivent® inhaler and children and for others who cannot use an inhaler. DuoNeb® nebulizing solution are combined beta agonist and anticholinergic products. The syrup and tablet forms work more slowly than the inhaled. They can also have more side effects. Still, they may be more convenient for those with few asthma episodes. Beta agonists may have side effects. Proper inhalation is key to ensure that the medication gets to the lungs. (See the section on inhalers later in this chapter.) In most cases, inhalers should not be used more than two puffs every four to six hours. If you need more relief than this, talk with your doctor. You may need a different drug. Overuse of beta agonists is a sign of asthma that is not controlled. It increases the chance for side effects. These may include fast heartbeat, jitters or headache. 16
Oxford Oral corticosteroids Other medications Oral corticosteroids are the strongest asthma drugs. Inflammation and mucus in the sinuses, nasal passages They are mainly used for those with severe asthma. and throat can affect the small airways in the lungs. They are also used to give fast relief from severe So drugs to relieve these symptoms can also help your episodes. They begin to work within 8 to 12 hours of asthma. Allergic rhinitis (hay fever) causes congestion, the first dose. They come in tablet or liquid forms. runny nose and other symptoms. Mild cases can be They manage asthma very well for short periods when treated with antihistamines and decongestants. other drugs do not work. Nasal corticosteroids may also be used. These are similar to inhaled corticosteroids but are used as a Side effects from short-term use (three to 10 days) are nasal spray. In severe cases, some of the asthma drugs unusual. Side effects may include weight gain, fluid may be prescribed. retention, mood changes, muscle pain, sleep issues and stomach aches. Most symptoms go away when the drugs are reduced or stopped. These drugs should be taken with food to prevent an upset stomach. They Get the most from should be used only with supervision by your health your medications care provider. Long-term use of oral corticosteroids is avoided due to possible side effects. People who have severe asthma }} Know what each medication you take is supposed that cannot be controlled with other drugs may need to to do. Know how much to take and how often. take them for longer periods. This should be done only with supervision by your provider. Your provider can }} Ask your doctor or pharmacist about side effects give you a dose that lowers the risk of side effects. This and how to minimize them. may mean taking the drugs every other morning. You }} Be sure to know if one medication should be may need to take other steps to avoid any side effects. taken before another. (For example, postmenopausal women may need to }} Follow all instructions with care. Take the take 1,000 to 1,500 mg of calcium and 400 units of medicine as directed by your doctor. vitamin D per day to prevent osteoporosis.) }} Follow all directions for devices such as nebulizers Oral corticosteroids used for asthma control are not the or inhalers with spacers. same as anabolic steroids used by some athletes. Oral }} Be prepared. Don’t run out of medications. corticosteroids are synthetic replicas of the steroids Always have an extra supply on hand. made in the body by the adrenal gland. Anabolic steroids are male hormones. They have a different }} Ask your provider if you should keep oral effect in the body than oral steroids. corticosteroids on hand for severe episodes. }} Asthma symptoms may change over time. Tell your doctor about any changes. The doses may need to be adjusted. }} Ask your doctor or pharmacist to check all new drugs for interactions with ones you are taking. 17
Oxford Administering asthma medications Nebulizers. You need special equipment for inhaled medications. Children too young to operate an inhaler are often Sometimes this is the container in which the drug is treated with a nebulizer. This device is also ideal for packaged. Other items, such as spacers or nebulizers, adults who have problems using MDIs. It is also used may be needed. Below are the systems for delivering for those with severe and erratic asthma episodes. inhaled drugs to the lungs. Nebulizers use compressed air to turn liquid medication into a fine mist that is breathed in through a mask Inhalers or mouthpiece. It may be used for bronchodilators, cromolyn sodium or the corticosteroid budesonide Metered-dose inhalers (Pulmicort Respules®). A metered-dose inhaler (MDI) is a small, portable canister. It delivers a measured amount of medication. Nebulizers are usually used in doctors’ offices and Proper technique and, in most cases, use of a spacer emergency rooms. They can also be purchased for home are needed to ensure that medication gets to the use. A home nebulizer can help prevent a trip to the lungs. The common errors people make when hospital. Many types of nebulizers are used. They range using inhalers are: from small battery packs to units that plug into a wall socket. }} Poor timing between activation of the MDI and inhalation. (An example is exhaling instead of When using a nebulizer at home, be sure to follow inhaling at the moment the medication is released.) your doctor’s directions. Nebulizers should not be overused or underused. The nebulizer cup and mask or }} Inhaling too rapidly mouthpiece should be rinsed out and air-dried after }} Not holding your breath briefly after inhaling. each use. Wash with soft water if possible. }} Not keeping the inhaler clean New devices. MDIs may not work properly if cold. If your MDI is Many new devices for asthma drugs have come out in exposed to cold, warm it in your hands before using. the last 10 years or so. They continue to develop new devices. The Turbuhaler® and Diskus® are among the Be sure the inhaler has medicine in it before you use most recent. These use inhaled powders. Your doctor it. If you use the same dose every day, you can calculate can tell you about more options if an MDI or nebulizer how long it will last. A canister with 200 doses will last does not meet your needs. 25 days if you use four puffs twice a day. (200 doses ÷ 8 puffs/day = 25 days.) Shaking the container is not a good way to tell if any medicine is left. Aerosols may be in the canister even after all the medicine is gone. Always keep an extra inhaler handy so you are sure not to run out. You need to keep your inhaler clean. To prevent clogging, rinse your inhaler daily. Keep the cap on when not in use. Wash your inhaler (except Intal® and Tilade®) once a week in warm water with a mild dish detergent. 18
Oxford Spacers If you use an MDI, you will probably also need to How to use an inhaler use a spacer. The spacer extends the space between the inhaler and your mouth. Examples of spacers are the AeroChamber®, InspirEase® or a plastic tube. Spacers make using inhalants easier. They let more of To be sure you are using your metered-dose inhaler the drug get deeper into the lungs. Without a spacer, correctly, stand in front of a mirror and follow the inhaled drugs tend to spray to the back of the throat steps below. If at any time fog comes from the mouth and go no farther. Spacers are important in preventing when inhaling or exhaling, the medication is not thrush. Thrush is a yeast condition that can be caused reaching the lungs. It is also wise to demonstrate by inhaled corticosteroids. If your inhaler makes you your inhaler technique to your health care provider cough, talk with your doctor. regularly to be certain you are doing it properly. 1. Shake the container well before using. Remove the cap, and hold the container upright. 2. Place a spacer on the end of the inhaler. If you don’t have one, roll up a piece of paper to act as a spacer. 3. Breathe out normally. Then place the spacer in your mouth and gently close your lips around it. 4. Press down on the top of the inhaler to release a puff of medication. Breathe in slowly and deeply through your mouth. 5. Keep breathing in slowly for three to five seconds until the lungs are full. 6. Hold your breath for 10 seconds to let the medicine deposit in the lungs. 7. Usually the next puff can be taken right away. In some cases, a one to three minute wait is advised before taking another puff. 8. Check with your doctor for directions for your medications. 19
Oxford Asthma medications Quick-relief Medications Class of Generic Names and Miscellaneous Information/ How Does It Work? Possible Side Effects Medication Available Forms Handling Side Effects Beta Agonists albuterol •R elaxes the smooth • Tremor, fast and/or • Side effects more common (Proventil®, muscles of the airways, pounding heartbeat, and stronger with oral Ventolin®) making it easier to nervousness and dizziness agents Metered-dose inhaler breathe (MDI), Solution for • Lasts 4-6 hours • If side effects are severe, inhalation, Syrup, and last longer than one Tablet hour, call your doctor levalbuterol (Xopenex®) Solution for inhalation metaproterenol sulfate (Alupent®) MDI, Solution for inhalation pirbuterol acetate (Maxair®, Maxair® Autohaler®) MDI terbutaline Tablet Anticholinergics ipratropium •R elaxes the smooth • Dry mouth, cough, rapid • Most often used in bromide muscles of the airways by heartbeat, blurred vision, combination with a MDI, Solution for inhibiting the action of headache and nervousness beta-agonist inhalation acetylcholine • Lasts 6-8 hours Beta Agonists ipratropium • Relaxes the smooth • Dry mouth, cough, rapid Combination bromide/albuterol muscles of the airways, heartbeat, blurred vision, Anticholinergics/ sulfate making it easier headache, nervousness (Combivent,® to breathe and tremor Duoneb®) • Lasts 4-6 hours MDI, Solution for inhalation Corticosteroids methylprednisolone •R educes swelling, • Increased appetite, stomach • Take with food to avoid (Medrol®) inflammation and mucus ache, mood changes, stomach ache Tablet production in the airways muscle pain, fluid retention • Potential for side effects and increased blood sugars is dose-related prednisone • Long-term use may cause (many brands) more severe side effects Tablet, Syrup prednisolone (Prelone,® Pediapred®) Syrup 20
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