The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal Update

Page created by Frederick Casey
 
CONTINUE READING
POLICY STATEMENT           Organizational Principles to Guide and Define the Child Health
                                                         Care System and/or Improve the Health of all Children

                              The Impact of Marijuana Policies on
                              Youth: Clinical, Research, and Legal
                              Update
                              COMMITTEE ON SUBSTANCE ABUSE and COMMITTEE ON ADOLESCENCE

This policy statement is an update of the American Academy of Pediatrics              abstract
policy statement “Legalization of Marijuana: Potential Impact on Youth,”
published in 2004. Pediatricians have special expertise in the care of children
and adolescents and may be called on to advise legislators about the potential
impact of changes in the legal status of marijuana on adolescents. Parents
also may look to pediatricians for advice as they consider whether to support
state-level initiatives that propose to legalize the use of marijuana for medical
and nonmedical purposes or to decriminalize the possession of small amounts
of marijuana. This policy statement provides the position of the American
Academy of Pediatrics on the issue of marijuana legalization. The
accompanying technical report reviews what is currently known about the
relationships of marijuana use with health and the developing brain and the
legal status of marijuana and adolescents’ use of marijuana to better
understand how change in legal status might influence the degree of
                                                                                      This document is copyrighted and is property of the American
marijuana use by adolescents in the future.                                           Academy of Pediatrics and its Board of Directors. All authors have filed
                                                                                      conflict of interest statements with the American Academy of
                                                                                      Pediatrics. Any conflicts have been resolved through a process
                                                                                      approved by the Board of Directors. The American Academy of
                                                                                      Pediatrics has neither solicited nor accepted any commercial
                                                                                      involvement in the development of the content of this publication.
DEFINITIONS
                                                                                      Policy statements from the American Academy of Pediatrics benefit
For the purpose of clarifying terminology, the following are definitions               from expertise and resources of liaisons and internal (AAP) and
used in this policy statement and the accompanying technical report1:                 external reviewers. However, policy statements from the American
                                                                                      Academy of Pediatrics may not reflect the views of the liaisons or the
                                                                                      organizations or government agencies that they represent.
Legalization
                                                                                      The guidance in this statement does not indicate an exclusive course
Allowing cultivation, sale, and use of cannabis (restricted to adults                 of treatment or serve as a standard of medical care. Variations, taking
$21 years of age).                                                                    into account individual circumstances, may be appropriate.

                                                                                      All policy statements from the American Academy of Pediatrics
Legalization of Medical Marijuana                                                     automatically expire 5 years after publication unless reaffirmed,
                                                                                      revised, or retired at or before that time.
Allowing the use of marijuana to treat a medical condition or symptom
with a recommendation from a physician.                                               www.pediatrics.org/cgi/doi/10.1542/peds.2014-4146

                                                                                      DOI: 10.1542/peds.2014-4146

                                                                                      PEDIATRICS (ISSN Numbers: Print, 0031-4005; Online, 1098-4275).

                                                                                      Copyright © 2015 by the American Academy of Pediatrics

                              Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
PEDIATRICS Volume 135, number 3, March 2015                                         FROM THE AMERICAN ACADEMY OF PEDIATRICS
Decriminalization                          marijuana did not start in Colorado         decreasing nausea and vomiting in
Reducing penalties for cannabis-           until January 1, 2014, the                  patients with cancer and for chronic
related offenses to lesser criminal        postlegalization 2013 rates of youth        pain syndromes,5,6 although side
charges or to civil penalties.             use increased.4 It is possible that         effects of dizziness and dysphoria
                                           public health campaigns that                may also be experienced. There are
                                           effectively communicate the harms           no published studies on the use of
INTRODUCTION                               associated with teen marijuana use          medicinal marijuana or
Marijuana is the most commonly             could reduce youth use despite              pharmaceutical cannabinoids in
used illicit substance among               legalization. Legalization campaigns        pediatric populations.
adolescents.2 Recreational sale and        that imply that marijuana is a benign
possession of marijuana by adults          substance present a significant
remain illegal in most states and          challenge for educating the public          EFFECTS OF MARIJUANA
remain illegal under federal law.          about its known risks and adverse           The adverse effects of marijuana have
However, a number of states and            effects. Therefore, it is unclear what      been well documented, and studies
local jurisdictions have                   the impact of legalization of               have demonstrated the potential
decriminalized the possession of           marijuana for adults will have on the       negative consequences of short- and
marijuana for recreational use by          prevalence of marijuana use by              long-term recreational use of
adults, reducing penalties to              adolescents, especially if the              marijuana in adolescents. These
misdemeanors or citations. Many            implementation of legalization              consequences include impaired short-
states also have legalized medical         includes messaging that minimizes           term memory and decreased
marijuana for adults who receive           the health and behavioral risks.            concentration, attention span, and
recommendations for use by                 Substance abuse by adolescents is an        problem solving, which clearly
physicians. Almost all states with         ongoing health concern. Marijuana           interfere with learning. Alterations in
medical marijuana laws allow access        remains classified in the Controlled         motor control, coordination,
by minors, though often with greater       Substances Act (21 USC x801-971             judgment, reaction time, and tracking
regulation. States in which marijuana      [2012]) as a schedule I drug. This          ability have also been documented7;
is legal prohibit marijuana sales to       classification implies that it has           these may contribute to unintentional
and use by minors, but changes in          a high potential for abuse, has no          deaths and injuries among
the legal status of marijuana, even if     currently accepted medical use in the       adolescents (especially those
limited to adults, may affect the          United States, and lacks accepted           associated with motor vehicles if
prevalence of use among                    safety for use under supervision by         adolescents drive while intoxicated
adolescents. Although the                  a physician. Despite this                   by marijuana).8 Negative health
epidemiologic data are not                 classification by the federal                effects on lung function associated
consistent across states and time          government, marijuana has been              with smoking marijuana have also
periods, with the exception of             legalized for medical purposes in           been documented, and studies linking
Michigan and New Mexico, in all            a number of states, in direct               marijuana use with higher rates of
states where medical marijuana has         opposition to federal law. Since the        psychosis in patients with
been legalized, marijuana use by           first policy statement from the              a predisposition to schizophrenia
minors has been stable or has              American Academy of Pediatrics              have recently been published,9 raising
decreased.3 Youth substance use            (AAP) on the legalization of                concerns about longer-term
rates depend on a number of factors,       marijuana was published in 2004,            psychiatric effects. New research has
including legal status, availability       limited research has been performed         also demonstrated that the
and ease of access of the substance,       to examine the potential therapeutic        adolescent brain, particularly the
and perception of harm. For example,       effects of marijuana for adults,            prefrontal cortex areas controlling
although tobacco is easily accessible,     specifically the class of chemicals          judgment and decision-making, is not
youth tobacco use rates have               known as cannabinoids, which are            fully developed until the mid-20s,
decreased substantially since the          responsible for most of the medicinal       raising questions about how any
1990s, in conjunction with                 effects of marijuana. This research         substance use may affect the
aggressive public health campaigns         has demonstrated that both the              developing brain. Research has
warning of the medical                     drugs approved by the US Food and           shown that the younger an adolescent
consequences of smoking. In                Drug Administration and other               begins using drugs, including
Colorado, the passage of the               pharmaceutical cannabinoids, such           marijuana, the more likely it is that
amendment to legalize recreational         as cannabidiol, can be helpful for          drug dependence or addiction will
marijuana occurred in November             adults with specific conditions, such        develop in adulthood.10 A recent
2012. Although sales of recreational       as increasing appetite and                  analysis of 4 large epidemiologic

                           Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
2                                                                                          FROM THE AMERICAN ACADEMY OF PEDIATRICS
trials found that marijuana use during          medical marijuana and the adverse                a schedule II drug to facilitate
adolescence is associated with                  effects of marijuana use, the impact of          this research.
reductions in the odds of high school           criminal penalties particularly on            6. Although the AAP does not
completion and degree attainment                minority teens and communities, and              condone state laws that allow the
and increases in the use of other illicit       adolescent brain development related             sale of marijuana products,
drugs and suicide attempts in a dose-           to substance use, is available in the            in states where recreational
dependent fashion that suggests that            accompanying technical report.1                  marijuana is currently legal,
marijuana use is causative.11                                                                    pediatricians should advocate
                                                                                                 that states regulate the product
DECRIMINALIZATION EFFORTS AND                   RECOMMENDATIONS                                  as closely as possible to tobacco
EFFECTS                                          1. Given the data supporting the                and alcohol, with a minimum age
The illegality of marijuana has                     negative health and brain de-                of 21 years for purchase. Revenue
resulted in the incarceration of                    velopment effects of marijuana in            from this regulation should be
hundreds of thousands of                            children and adolescents, ages               used to support research on the
adolescents, with overrepresentation                0 through 21 years, the AAP is               health risks and benefits of
of minority youth.12 A criminal record              opposed to marijuana use in this             marijuana. These regulations should
can have lifelong negative effects on               population.                                  include strict penalties for those
an adolescent who otherwise has had              2. The AAP opposes “medical                     who sell marijuana or marijuana
no criminal justice history. These                  marijuana” outside the regulatory            products to those younger than
effects can include ineligibility for               process of the US Food and Drug              21 years, education and diversion
college loans, housing, financial aid,               Administration. Notwithstanding              programs for people younger than
and certain kinds of jobs.13 In states              this opposition to use, the AAP              21 years who possess marijuana,
that have passed decriminalization                  recognizes that marijuana                    point-of-sale restrictions, and
laws, marijuana use is still illegal,               may currently be an option for               other marketing restrictions.
although the consequences of                        cannabinoid administration for            7. In states where marijuana is sold
possession and use are less punitive.               children with life-limiting or               legally, either for medical or
Although these laws are not                         severely debilitating conditions             recreational purposes, regulations
applicable to adolescents in all states,            and for whom current therapies               should be enacted to ensure that
the changes in the law are intended to              are inadequate.                              marijuana in all forms is distributed
address and reduce the long-term                 3. The AAP opposes legalization                 in childproof packaging, to
effects that felony charges can have                of marijuana because of the                  prevent accidental ingestion.
on youth and young adults.13                        potential harms to children and           8. The AAP strongly supports the de-
Continued efforts to address this                   adolescents. The AAP supports                criminalization of marijuana use
problem are based on issues of social               studying the effects of recent               for both minors and young adults
justice, given the disparate rate of                laws legalizing the use of marijuana         and encourages pediatricians to
adjudication for drug offenses for youth            to better understand the impact              advocate for laws that prevent
of racial minority groups compared                  and define best policies to reduce            harsh criminal penalties for
with white youth. Advocates of                      adolescent marijuana use.                    possession or use of marijuana. A
decriminalization have also sought                                                               focus on treatment for adolescents
                                                 4. In states that have legalized
to increase the availability of drug                                                             with marijuana use problems should
                                                    marijuana for recreational
treatment services.14                                                                            be encouraged, and adolescents
                                                    purposes, the AAP strongly
                                                    recommends strict enforcement                with marijuana use problems
CONCLUSIONS                                         of rules and regulations that                should be referred to treatment.
Ultimately, the behavioral and health               limit access and marketing and            9. The AAP strongly opposes the use of
risks associated with marijuana use                 advertising to youth.                        smoked marijuana because smoking
by youth should be the most salient              5. The AAP strongly supports                    is known to cause lung damage,15
criteria in determining whether                     research and development of                  and the effects of secondhand
policies that are enacted are effective             pharmaceutical cannabinoids and              marijuana smoke are unknown.
in minimizing harm. More                            supports a review of policies           10. The AAP discourages the use of
information, including the legal status             promoting research on the                   marijuana by adults in the pres-
of marijuana for both recreational                  medical use of these compounds.             ence of minors because of the im-
and medical use, the effect of legal                The AAP recommends changing                 portant influence of role modeling
status on rates of use by adolescents               marijuana from a Drug Enforcement           by adults on child and adolescent
and young adults, research on                       Administration schedule I to                behavior.

                                Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
PEDIATRICS Volume 135, number 3, March 2015                                                                                          3
LEAD AUTHORS                                             report: the impact of marijuana policies         driving performance. Publication no.
Seth D. Ammerman, MD, FAAP                               on youth: clinical, research, and legal          808–078. Washington, DC: US Department
Sheryl A. Ryan, MD, FAAP                                 update. Pediatrics. 2015; (in press)             of Transportation; 1993. Available at:
*William P. Adelman, MD, FAAP                          2. Monitoring the Future. Trends in 30-day         http://druglibrary.org/schaffer/misc/
                                                          prevalence of use of various drugs in           driving/driving.htm. Accessed October 3,
COMMITTEE ON SUBSTANCE ABUSE,                                                                             2014
                                                          grades 8, 10, and 12. Table 3. Ann Arbor,
2014–2015
                                                          MI: University of Michigan; 2013.            9. Moore THM, Zammit S, Lingford-Hughes
Sharon Levy, MD, MPH, FAAP, Chairperson                   Available at: www.monitoringthefuture.          A, et al. Cannabis use and risk of
Seth D. Ammerman, MD, FAAP
                                                          org/data/10data/pr10t3.pdf                      psychotic or affective mental health
Pamela K. Gonzalez, MD, FAAP
                                                       3. Lynne-Landsman SD, Livingston MD,               outcomes: a systematic review. Lancet.
Sheryl A. Ryan, MD, FAAP
Lorena M. Siqueira, MD, MSPH, FAAP                        Wagenaar AC. Effects of state medical           2007;370(9584):319–328. Available at:
Vincent C. Smith, MD, MPH, FAAP                           marijuana laws on adolescent marijuana          www.ncbi.nlm.nih.gov/pubmed/
                                                          use. Am J Public Health. 2013;103(8):           17662880. Accessed October 3, 2014
LIAISONS
                                                          1500–1506. Available at: www.               10. Schepis TS, Adinoff B, Rao U.
Vivian B. Faden, PhD – National Institute of Alcohol      pubmedcentral.nih.gov/articlerender.            Neurobiological processes in adolescent
Abuse and Alcoholism                                      fcgi?artid=4007871&tool=                        addictive disorders. Am J Addict. 2008;17
Gregory Tau, MD, PhD – American Academy of Child          pmcentrez&rendertype=abstract.                  (1):6–23. Available at: www.
and Adolescent Psychiatry
                                                          Accessed October 1, 2014                        pubmedcentral.nih.gov/articlerender.
STAFF                                                  4. Substance Abuse and Mental Health               fcgi?artid=2274940&tool=
                                                          Services Administration. Results from           pmcentrez&rendertype=abstract.
James Baumberger, MPP
                                                          the 2013 NSDUH: Summary of National             Accessed September 3, 2014
Katie Crumley, MPP
Renee Jarrett, MPH                                        Findings. In: N.S.D.U.H. series H-48, Vol   11. Silins E, Horwood LJ, Patton GC, et al.
                                                          HHS Public. Rockville, MD: Substance            Young adult sequelae of adolescent
COMMITTEE ON ADOLESCENCE,                                 Abuse and Mental Health Services                cannabis use: an integrative analysis.
2014–2015                                                 Administration; 2014:14–4863. Available         Lancet Psychiatry. 2014;1(4):286–293.
Paula K. Braverman, MD, FAAP, Chairperson                 at: www.samhsa.gov/data/NSDUH/                  Available at: www.thelancet.com/
*William P. Adelman, MD, FAAP                             2013SummNatFindDetTables/                       journals/a/article/PIIS2215-0366(14)
Elizabeth Meller Alderman, MD, FSAHM, FAAP                NationalFindings/NSDUHresults2013.htm.          70307-4/fulltext. Accessed September 10,
Cora C. Breuner, MD, MPH, FAAP                            Accessed October 1, 2014                        2014
David A. Levine, MD, FAAP
Arik V. Marcell, MD, FAAP                              5. Aggarwal SK, Carter GT, Sullivan MD,        12. Science D. United States marijuana
Rebecca Flynn O’Brien, MD, FAAP                           ZumBrunnen C, Morrill R, Mayer JD.              arrests (1982–2008). Bull Cannabis
                                                          Medicinal use of cannabis in the United         Reform. 2009. Available at: www.
LIAISONS                                                  States: historical perspectives, current        drugscience.org/States/US/US_total.htm.
Margo Lane, MD, FRCPC – Canadian Pediatric Society        trends, and future directions. J. Opioid        Accessed October 1, 2014
Benjamin Shain, MD, PhD – American Academy of             Manag. 2009;5(3):153–168. Available at:     13. Males M, Buchen L. Reforming Marijuana
Child and Adolescent Psychiatry                           www.ncbi.nlm.nih.gov/pubmed/
Julie Strickland, MD – American College of                                                                Laws: Which Approach Best Reduces the
                                                          19662925. Accessed October 3, 2014              Harms of Criminalization? San Francisco,
Obstetricians and Gynecologists
Lauren B. Zapata, MD, PhD, MSPH – Centers for          6. Cotter J. Efficacy of crude marijuana and        CA: Center on Juvenile and Criminal
Disease Control and Prevention                            synthetic delta-9-tetrahydrocannabinol          Justice; 2014:1–13. Available at: www.cjcj.
                                                          as treatment for chemotherapy-induced           org/uploads/cjcj/documents/cjcj_
STAFF                                                     nausea and vomiting: a systematic               marijuana_reform_comparison.pdf
James Baumberger, MPP                                     literature review. Oncol Nurs Forum.        14. Drug Policy Alliance. Reforming
Karen S. Smith                                            2009;36(3):345–352                              marijuana laws. 2014. Available at: www.
*The views expressed are those of the author and
                                                       7. Schweinsburg AD, Nagel BJ,                      drugpolicy.org/reforming-marijuana-
do not necessarily reflect the policy or position of       Schweinsburg BC, Park A, Theilmann RJ,          laws. Accessed October 1, 2014
the Department of the Army, Department of                 Tapert SF. Abstinent adolescent             15. Volkow ND, Baler RD, Compton WM,
Defense, or the US Government.                            marijuana users show altered fMRI               Weiss SRB. Adverse health effects of
                                                          response during spatial working                 marijuana use. N Engl J Med. 2014;
REFERENCES                                                memory. Psychiatry Res. 2008;163(1):            370(23):2219–2227. Available at: www.
    1. American Academy of Pediatrics,                    40–51                                           nejm.org/doi/full/10.1056/
       Committee on Substance Abuse and                8. National Highway Traffic Safety                  NEJMra1402309?query=featured_
       Committee on Adolescence. Technical                Administration. Marijuana and actual            home&. Accessed July 30, 2014

                                      Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
4                                                                                                         FROM THE AMERICAN ACADEMY OF PEDIATRICS
The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal
                                    Update
COMMITTEE ON SUBSTANCE ABUSE and COMMITTEE ON ADOLESCENCE
           Pediatrics; originally published online January 26, 2015;
                        DOI: 10.1542/peds.2014-4146
 Updated Information &               including high resolution figures, can be found at:
 Services                            http://pediatrics.aappublications.org/content/early/2015/01/20
                                     /peds.2014-4146
 Permissions & Licensing             Information about reproducing this article in parts (figures,
                                     tables) or in its entirety can be found online at:
                                     http://pediatrics.aappublications.org/site/misc/Permissions.xh
                                     tml
 Reprints                            Information about ordering reprints can be found online:
                                     http://pediatrics.aappublications.org/site/misc/reprints.xhtml

 PEDIATRICS is the official journal of the American Academy of Pediatrics. A monthly
 publication, it has been published continuously since 1948. PEDIATRICS is owned, published,
 and trademarked by the American Academy of Pediatrics, 141 Northwest Point Boulevard, Elk
 Grove Village, Illinois, 60007. Copyright © 2015 by the American Academy of Pediatrics. All
 rights reserved. Print ISSN: 0031-4005. Online ISSN: 1098-4275.

               Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal
                                    Update
COMMITTEE ON SUBSTANCE ABUSE and COMMITTEE ON ADOLESCENCE
           Pediatrics; originally published online January 26, 2015;
                        DOI: 10.1542/peds.2014-4146

 The online version of this article, along with updated information and services, is
                        located on the World Wide Web at:
    http://pediatrics.aappublications.org/content/early/2015/01/20/peds.2014-4146

   PEDIATRICS is the official journal of the American Academy of Pediatrics. A monthly
   publication, it has been published continuously since 1948. PEDIATRICS is owned,
   published, and trademarked by the American Academy of Pediatrics, 141 Northwest Point
   Boulevard, Elk Grove Village, Illinois, 60007. Copyright © 2015 by the American Academy
   of Pediatrics. All rights reserved. Print ISSN: 0031-4005. Online ISSN: 1098-4275.

              Downloaded from pediatrics.aappublications.org by guest on March 4, 2015
You can also read