The Blue Book A Course Guide for the Secondary Field in Global Health and Health Policy

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The Blue Book
A Course Guide for the
Secondary Field in
Global Health and Health Policy

2021–2022

Website:    http://ghhp.fas.harvard.edu/

Office:     GHHP Advising and Administrative Office
            14 Story Street, 4th floor
            Cambridge, MA 02138

Contacts:   Christy Colburn: christy_colburn@harvard.edu
            Debbie Whitney: deborah_whitney@harvard.edu
Contents

                             What Can You Expect from Global Health
                             and Health Policy? 3

                             This Booklet 4

                             Secondary Field Requirements 5

                             Course Listings by GHHP Category

                                 Foundational Courses 6

                                 Research Courses 7

                                 Economics of Health 8

                                 Engineering Sciences and Statistics 9

                                 Ethics of Health 12

                                 Health and Demography 16

                                 Health, Culture, and Society 17

                                 History and Practice of Medicine 22

                                 Politics of Health 25

                                 Science of Health and Disease 27

                             Index of Courses 34

Rev 08/16/21   Course Guide for the Secondary Field in Global Health and Health Policy 1
Rev 08/16/21   Course Guide for the Secondary Field in Global Health and Health Policy 2
What Can You Expect
from Global Health and
Health Policy?

Interdisciplinary Approach                                      Experiential Learning

Explore interdisciplinary world health challenges from          Studying global health and health policy requires integrative
many perspectives; use different disciplinary approaches to     experiential learning to connect the knowledge and skills
learn about health care delivery, health systems, public        learned in the classroom to real-world complexities. You
health and health policy. Courses in the GHHP Secondary         can take advantage of more than 50 summer internships,
Field sit within three schools and 27 FAS departments.          both domestic and abroad, and continue your work as part of
These courses represent an array of perspectives on global      your research requirement. More information about summer
health topics and can inform your course of study both in       opportunities and funding can be found at
and out of the classroom.                                       https://ghhp.fas.harvard.edu/ExperientialLearning.

Local and Global Perspective                                    Faculty Mentorship

Learn how health is influenced by social, economic,             Learn from faculty members teaching global health courses
political, cultural, and environmental factors, both locally    from across the university and receive one-on-one
and globally. Your GHHP Secondary Field could include           mentorship on independent research. Participate in Harvard
any of the above topics or move into themes such as: global     Global Health Institute workshops and student roundtables.
governance for health; the relevance and morality of            Work with faculty on research in their field or get valuable
socioeconomic inequality in health; consequences of politics    advice on projects of your own creation.
and the role of health in foreign policy, national security,
and economic development.

Explore the Connections

Learn about the rising global burden of chronic diseases in
high-, low-, and middle-resource countries; the emergence
of pandemic diseases and their economic and psychological
impact; health consequences of travel, urbanization and
migration, wars and ethnic conflict; changes in climate and
other environmental factors, including water and food
security.

Rev 08/16/21                                      Course Guide for the Secondary Field in Global Health and Health Policy 3
This Booklet                                                       GPA except when the courses are counted toward
                                                                   concentration requirements. Students wishing to cross-
                                                                   register should consult the discussion of cross-registration in
                                                                   the FAS Handbook for Students at this webpage:
                                                                   https://handbook.fas.harvard.edu/book/cross-registration.

                                                                   Prerequisites and Instructor Permission
The courses listed in this booklet fulfill requirements of the
Secondary Field in Global Health and Health Policy                 The courses listed in this booklet are suggestions for
(GHHP). The booklet includes courses that are listed in the        undergraduates who are interested in learning more about
my.harvard.edu as of August 16, 2021. Since the terms and          global health and health policy or the application of other
times in which courses are offered can change from time to         disciplines to global health/health policy issues. It is the
time, students should consult my.harvard.edu for the most          responsibility of students to ensure that they have the
accurate, up-to-date information.                                  correct prerequisites and the permission of the instructor,
                                                                   when required, before they enroll in a course.

Spreadsheet of Courses
                                                                   Questions or Comments?
A list of courses that fulfill the various requirements of the
Secondary Field in Global Health and Health Policy is              Do you have any comments about this booklet? Do you
available as a sortable spreadsheet on the GHHP website:           know of a course that is not listed here and should be?
https://ghhp.fas.harvard.edu/courses-0. Note that the              Would you like to receive a copy of this booklet in future
spreadsheet has two tabs at the bottom: the left tab lists         years and/or an extra copy of this year’s booklet? Please
courses that appear in the 2021-22 course catalogs, while          contact us at ghhp@fas.harvard.edu.
the right tab lists courses that were offered in the past and
still count for GHHP credit.

Petitioning Courses for GHHP Credit

Students may petition to have courses not listed in the Blue
Book count for GHHP Secondary Field credit. A course will
not be approved unless it has substantial global health or
health policy content. To petition a course, email your
request to ghhp@fas.harvard.edu, attach a syllabus, and
explain which category within the GHHP Secondary Field
you believe the course satisfies. Note that the only HSPH
courses listed in the Blue Book are those that have been
petitioned previously. It is likely that the majority of courses
offered at HSPH, once petitioned and reviewed, would
count for GHHP; however, be aware that many courses
offered at HSPH are half-semester courses and provide only
half the credit of a semester-long course in FAS.

Cross-Registration

Students must cross-register in order to take classes in
Harvard schools outside of FAS. Policies and deadlines for
cross-registration generally vary from school to school.
Note that passing grades received for cross-registered
courses will not be used in computing a student’s

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Harvard Secondary Field
in Global Health and Health
Policy Requirements

In total, five courses (20 credits) are required:

One Foundational Course:                                          Three Additional Courses, one course in three
                                                                  of the following eight categories:
•   GENED 1063: World Health: Challenges and
    Opportunities [Formerly "Societies of the World 24: Is        Humanities and Social Sciences
    Globalization Good or Bad for World Health?"]                     • Economics of Health
•   GENED 1079: Why is There No Cure for Health?                      • Ethics of Health
    [Formerly "Empirical and Mathematical Reasoning                   • Health and Demography
    20”]                                                              • Health, Culture, and Society
•   GENED 1093: Who Lives, Who Dies, Who Cares?                       • History and Practice of Medicine
    Reimagining Global Health [Formerly "Societies of the             • Politics of Health
    World 25: Case Studies in Global Health: Biosocial            Sciences
    Perspectives"]                                                    • Engineering Sciences and Statistics
                                                                      • Science of Health and Disease
•   Not Offered in 2021-2022: GENED: USW 11
    American Health Care Policy                                   Course options for the eight categories are listed in this Blue
                                                                  Book. Note that the eight categories are divided into two
                                                                  areas, Humanities & Social Sciences, and Sciences.
One Research Course:                                              Students are strongly encouraged to take at least one course
                                                                  from both areas.
•   One term of the senior thesis tutorial, when the thesis
    pertains to global health or health policy
•   One term of the senior thesis tutorial, when students         Other Information:
    write an additional thesis chapter on the global health or
    health policy implications of their hard science,             •   Only one of the five courses may be non-letter-graded.
    engineering, or computer science thesis                           (Exception: Two courses may be taken non-letter-
•   Global Health and Health Policy 99: Research in Global            graded if one is the senior thesis tutorial used to satisfy
    Health and Health Policy                                          the research requirement.)
•   Supervised Reading and Research course (GHHP 91 or            •   Only one course may double count for a secondary field
    equivalent course in another department), culminating             and concentration.
    in a research paper pertaining to global health or health     •   A maximum of two non-FAS courses may count for the
    policy                                                            GHHP Secondary Field. This includes courses taken at
                                                                      other Harvard schools, including Harvard Summer
Additional guidelines regarding the research requirement              School, and courses taken in study abroad programs.
are available at http://ghhp.fas.harvard.edu

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Course Listings by GHHP                                          reform its health care system? And how should prescription
                                                                 drugs be produced and sold?

Category                                                         We will explore how social scientists address empirical
                                                                 questions, the types of data that are available, how those
                                                                 data are analyzed, and the confidence with which causal
                                                                 statements are made. By the end of the course, you will be
                                                                 able to dissect a large question—such as how to reform
                                                                 American healthcare—into its technological, social,
                                                                 economic, and moral components, and weigh potential
                                                                 solutions according to these guiding vectors.
FOUNDATIONAL COURSES
                                                                 GENED 1093: Who Lives, Who Dies, Who Cares?
                                                                 Reimagining Global Health
GENED 1063: World Health: Challenges and                         Arthur Kleinman, Salmaan Keshavjee, Anne Becker, Paul
Opportunities                                                    Farmer,
Sue J. Goldie                                                    Fall; TTh 10:30-11:45
Spring; MW 10:30-11:45                                           If you are sick or hurt, whether you live or die depends not
Class Capacity: 200                                              only on biological factors, but social ones: who you are and
Consent Required: Instructor                                     where you are, what sort of healthcare system is available to
Extraordinary changes in the world present both risks and        help you survive, and what kind of care is available to help
opportunities to health—unprecedented interconnections           you recover, if society believes you deserve it. The global
across borders, rapidly shifting global demographics, and        coronavirus pandemic illustrates with dramatic urgency the
changing patterns of diseases and injuries. This course will     role social forces play in patterning health inequities and
challenge your assumptions about the world’s populations,        determining individual fates. The vulnerabilities of those
as you discover surprising similarities and unexpected           most likely to get sick and to die from Covid-19 stem from
differences between and within countries. Approaching the        the ongoing effects of systemic racism on racialized
concept of health as a fundamental prerequisite for building     subjects, the devaluation of eldercare and precarity of low-
strong societies, we will explore its connection to human        paid work under neoliberal forms of governance, and
rights, international relations, and sustainable development.    enduring material effects of colonial-era power structures
Using case examples of contemporary health challenges, we        that render health care systems dangerously weak or
explore the influence of social, political, and environmental    inaccessible for many communities. Now, as ever, it is
determinants on health, particularly transnational risks         imperative to develop frameworks and methodologies to
associated with globalization. We consider solutions from        identify and to intervene effectively in harmful social
an array of perspectives, contributions from within and          configurations that cause illness and suffering.
outside the health sector, and interventions at the local,       Most medical research narrowly focuses on the biological
national and global levels. By the end of the course, you will   basis of disease, but this course takes a novel biosocial
be equipped to thoughtfully analyze important health             approach to reveal how governments, institutions, and
challenges and appreciate how evidence is contextualized         histories shape health and well-being, how poverty and
and translated to policy and action.                             racism get into someone’s lymph nodes, how cost- saving
                                                                 measures manifest as tuberculosis in someone’s lungs. In
GENED 1079: Why is There No Cure for Health?                     doing so, the course challenges conventional assumptions
David Cutler                                                     within the field of global health—examining how
Fall; TTh 12-1:15                                                interventions influence what happens after a catastrophe in
Around the world, billions of dollars are spent on health        unexpected ways, how the persistence of health inequalities
care treatments, public health initiatives, and pharmaceutical   over centuries can be explained, how the structures of
research and development. So why are we still not able to        powerful institutions influence the policies they develop,
prevent preventable diseases, provide affordable healthcare      how the poor deserve not only health care but high quality
for millions of people, and deliver cures for curable            health care, and how caregiving and global health are urgent
diseases? And what are the best ways to address these            moral practices.
issues?
Because these questions are so large, we will focus our
discussion around questions like: What steps should be
taken to address epidemics? How should the United States

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RESEARCH COURSES

Global Health and Health Policy 91: Supervised Reading
and Research
David Cutler
Fall and Spring
Consent Required: Instructor
Supervised reading leading to a long term paper on a topic
or topics not covered by regular courses of instruction.
Course Notes: May not be taken Pass/Fail. To enroll in the
course, a written proposal and signature of advisor and chair
of GHHP Committee is required. Refer to GHHP website
for enrollment requirements and instructions:
https://ghhp.fas.harvard.edu/ghhp-91

Global Health and Health Policy 99: Research in Global
Health and Health Policy
David Cutler
Spring; W 3-5
Consent Required: Instructor
Global health and health policy are interdisciplinary fields
that apply the theories and methods of statistics, sociology,
political science, economics, management, decision science,
and philosophy to the study of population health and health
care. Research from these fields influences policymaking in
a variety of settings. For example, the Patient Protection and
Affordable Care Act (ACA) drew upon health policy
research to develop programs for improving access and
quality of care in the United States. Similarly, global health
research guides international institutions, such as the World
Health Organization, in determining health guidelines for all
countries. Global health and health policy research can also
inform practices inside hospitals, initiate programs for
diseases like HIV, and regulate the food and drug industries.
This course introduces the fundamentals of research design
and methods in global health and health policy and assists
students in developing research projects and crafting policy
recommendations that can impact health care systems and
public health.
Course Notes:
This course fulfills the research requirement of the
Secondary Field in Global Health and Health Policy, and
enrollment is ordinarily limited to seniors in the GHHP
Secondary Field. Underclass GHHP students may petition to
take the course if all other Secondary Field requirements
have been met. GHHP 99 is primarily taught by graduate
students in the PhD in Health Policy program. It may not be
taken pass/fail.

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ECONOMICS OF HEALTH                                              We will explore how social scientists address empirical
                                                                 questions, the types of data that are available, how those
                                                                 data are analyzed, and the confidence with which causal
Freshman Seminar 40k: America's $4 Trillion Challenge:           statements are made. By the end of the course, you will be
Boosting Health Care Productivity and Broadening                 able to dissect a large question—such as how to reform
Access                                                           American healthcare—into its technological, social,
Alan Garber                                                      economic, and moral components, and weigh potential
Spring; TBA                                                      solutions according to these guiding vectors.
Class Capacity: 12
Consent Required: Instructor                                     Biological Chemistry and Molecular Pharmacology 230:
"Why does health care cost so much?" Policymakers,               Principles and Practice of Drug Development
employers, and the public share deep frustration at high         Stan Finkelstein; Peter Sorger
health expenditures, which are blamed for rising federal         Fall; W 3-6
deficits, the declining competitiveness of US businesses,        Critical assessment of the major issues and stages of
and the risk of financial ruin for individuals unfortunate       developing a pharmaceutical or biopharmaceutical. Drug
enough to suffer a costly illness or injury. Unless health       discovery, preclinical development, clinical investigation,
expenditures can be controlled, universal access to care is      manufacturing and regulatory issues considered for small
likely to remain an unattainable goal in the United States. In   and large molecules. Economic considerations of the drug
this seminar, we will explore the causes and consequences        development process.
of the high costs of care and the range of approaches to         Class Notes: Wed., 3:00pm - 6:00pm
increasing the productivity of health care. The Affordable       Meeting Dates: Sept. 8 – Dec. 8, 2021
Care Act and alternative health reform options will be           Meeting Location: MIT 4-237
critically examined for their effects on health care
productivity. Students will be exposed to techniques for         XREG: SUP 518: The Economics of Infectious Disease
measuring the effectiveness and value of health care, and        Marcella Alsan
will become familiar with economic and clinical studies.         Fall; MW 3-4:15
Students will be asked to produce a mid-term outline and         Class Capacity: 75
final paper on solutions for improving health care               The course introduces and applies economic models and
productivity in the US. .                                        econometric tools to the analysis infectious diseases.
Recommended Prep: Background in microeconomics at the            Specific diseases will be discussed and recent research
level of first-semester Economics 10 is required. Knowledge      reviewed.
of AP-level statistics is desirable. The course is relevant to   Recommended Prep: Prior experience with statistics and/or
anyone with an interest in applied economics, public policy,     econometrics and/or microeconomics and/or infectious
health care, or public health.                                   disease is helpful but not mandatory. Undergraduates may
Course Requirements: Course open to Freshman Students            take SUP 518 as part of their economics concentration.
Only.

GENED 1079: Why is There No Cure for Health?
David Cutler
Fall; TTh 12-1:!5
Around the world, billions of dollars are spent on health
care treatments, public health initiatives, and pharmaceutical
research and development. So why are we still not able to
prevent preventable diseases, provide affordable healthcare
for millions of people, and deliver cures for curable
diseases? And what are the best ways to address these
issues?
Because these questions are so large, we will focus our
discussion around questions like: What steps should be
taken to address epidemics? How should the United States
reform its health care system? And how should prescription
drugs be produced and sold?

Rev 08/16/21                                       Course Guide for the Secondary Field in Global Health and Health Policy 8
ENGINEERING SCIENCES AND STATISTICS                              Economics 1123: Introduction to Econometrics
                                                                 Davide Pettenuzzo (Fall), Gregory Bruich (Spring)
                                                                 Fall; MW 1:30-2:45
Applied Mathematics 101: Statistical Inference for               Spring; TTh 3-4:15
Scientists and Engineers                                         An introduction to multiple regression techniques with
Jeffrey Paten                                                    focus on economic applications. Discusses extensions to
Fall; MW 12:45-2                                                 discrete response, panel data, and time series models, as
Class Capacity: 55                                               well as issues such as omitted variables, missing data,
Consent Required: Instructor                                     sample selection, randomized and quasi-experiments, and
Introductory statistical methods for students in the applied     instrumental variables. Also develops the ability to apply
sciences and engineering. Random variables and probability       econometric and statistical methods using computer
distributions; the concept of random sampling, including         packages.
random samples, statistics, and sampling distributions; the      Course Notes: Students may take both Economics 1123 and
Central Limit Theorem; parameter estimation; confidence          Statistics 139 for credit. However, Statistics 139 will not
intervals; hypothesis testing; simple linear regression; and     count as the econometrics requirement for the economics
multiple linear regression. Introduction to more advanced        concentration. Only one course can count towards EC
techniques as time permits.                                      credit; either Economics 1123 or Economics 1126. Both
Recommended Prep: Math 21a or Applied Math 21a or                courses can count towards college credit regardless of the
equivalent.                                                      order they are taken.
                                                                 Recommended Prep: Statistics 100 and 104.
Biomedical Engineering 110: Physiological Systems
Analysis                                                         Economics 1126: Quantitative Methods in Economics
Maurice Smith                                                    Ellie Tamer
Fall; MW 3:45-5                                                  Fall; TTh 10:30-11:45
A survey of systems theory with applications from                Topics include conditional expectations and its linear
bioengineering and physiology. Analysis: differential            approximation; best linear predictors; omitted variable bias;
equations, linear and nonlinear systems, stability, the          panel data methods and the role of unobserved
complementary nature of time and frequency domain                heterogeneity; instrumental variables and the role of
methods, feedback, and biological oscillations.                  randomization; various approaches to inference on causal
Applications: nerve function, muscle dynamics,                   relations.
cardiovascular regulation. Laboratory: neural models,            Course Notes: Only one course can count towards EC
feedback control systems, properties of muscle,                  credit; either Economics 1123 or Economics 1126. Both
cardiovascular function.                                         courses can count towards college credit regardless of the
Recommended Prep: Engineering Sciences 53 (or                    order they are taken. Students who fulfill the econometrics
equivalent); Physical Sciences 12b (or equivalent); and          requirement with Economics 1126 and who intend to pursue
Math 21a and Math21b (or equivalents)                            Honors should note that the Honors exam assumes
                                                                 knowledge of the material covered in Economics 1123.
Biomedical Engineering 125: Tissue Engineering                   Recommended Prep: Math 18, 21a, Applied Math 21a.
David Mooney
Spring; TBA                                                      Engineering Sciences 6: Introduction to Environmental
Fundamental engineering and biological principles                Science and Engineering
underlying field of tissue engineering, along with examples      Steven Wofsy, Bryan Yoon
and strategies to engineer specific tissues for clinical use.    Spring; TBA
Students will prepare a paper in the field of tissue             This course will provide students with an introduction to
engineering, and participate in a weekly laboratory in which     current topics in environmental science and engineering by
they will learn and use methods to fabricate materials and       providing: an overview of current environmental issues,
perform 3-D cell culture.                                        critically evaluating their underlying science and knowledge
Recommended Prep: LS1a, Chem17 or 20, or biochemistry            limitations, and exploring the best-available engineering
and cell biology background.                                     solutions to some of our most pressing environmental
Jointy Offered with: Faculty of Arts & Sciences as ENG-          problems. The course will emphasize the interconnected
SCI 230                                                          biological, geological, and chemical cycles of the earth
                                                                 system (biogeochemical cycles) and how human activity
                                                                 affects these natural cycles within each of the major

Rev 08/16/21                                       Course Guide for the Secondary Field in Global Health and Health Policy 9
environmental compartments (atmospheric, aquatic, and           statistical techniques including linear, multiple linear, and
terrestrial).                                                   panel regression models; and Bayesian methods including
Course Notes: ESE 6 is also offered as EPS 6. Students may      empirical, full, and hierarchical approaches. You will be
not take both for credit.                                       provided with sufficient data, example code, and context to
Recommended Prep: The course presumes basic knowledge           come to your own informed conclusions regarding each of
in chemistry, physics, and mathematics at the high school       these questions. Furthermore, topics covered in class will
level.                                                          pro-vide a template for undertaking independent research
Jointly Offered with: Faculty of Arts & Sciences as E-PSCI      projects in small teams. Research will either extend on
6                                                               topics presented in class or address other human-
                                                                environmental questions. Historically, such student projects
Engineering Sciences 53: Quantitative Physiology as a           have sometimes led to senior theses or publication in
Basis for Bioengineering                                        professional journals.
Lindsey Moyer                                                   Course Notes: The course is designed for upper-level
Fall; MWF 11:15-12:30                                           undergraduates. Enrollment is by instructor permission. This
This course is designed as an introduction to thinking as a     course fulfills the EPS sub-discipline requirement of
bio/biomedical engineer and is recommended for first years      Atmosphere(s) and Oceans.
and sophomores but open to all students. Simple                 Recommended Prep: There are no specific prerequisites but
mathematical models are used to represent key aspects of        a background in environmental, physical or life sciences;
organ systems function. Core engineering concepts are           experience in coding or statistical analysis; and/or facility
explored through mechanical and electrical examples within      with differential equations is useful.
the human body. The primary focus is on quantitative            Jointly Offered with: Faculty of Arts & Sciences as ESE 168
descriptions of organ systems function and control in terms
of physical principles and physiologic mechanisms. It           Government 50: Data
includes a foundation in human organ systems physiology,        TBA
including cardiovascular, pulmonary, and renal systems.         Spring; TBA
Emphasis will be given to understanding the ways in which       This course, an introduction to quantitative political science,
dysfunction in these systems gives rise to common human         will teach you how to answer questions with data, how to
disease processes.                                              develop questions suited to empirical research, construct
Course Notes: Open to first-year students.                      hypotheses, conduct descriptive analysis using statistical
Recommended Prep: Calculus at the high school level             summaries and data visualizations, how to model
Course Requirements: Co-req or pre-req: Applied Physics         relationships, how to assess uncertainty, and how to
50a OR Applied Physics 50b OR Physical Sciences 12a OR          communicate your findings. Exercises both in and out of
Physical Sciences 12b OR Physics 15a OR Physics 15b OR          class will require students to engage with and apply various
PHYSCI 2 OR PHYSCI 3                                            social science concepts, and to undertake quantitative
                                                                analyses of political and policy-relevant data. Each student
Earth & Planetary Sciences 168: Human Environmental             will complete a final project.
Data Science: Agriculture, Conflict, and Health
Peter Huybers                                                   Molecular and Cellular Biology 111: Mathematics in
Fall; T 3:45-5:45                                               Biology
Consent Required: Instructor                                    Elena Rivas
The purpose of this course is to develop understanding and      Fall; MWF 10:30-11:45
guide student research of human and environmental               MCB111 is meant for biologists who want to learn
systems. In class we will explore agriculture, conflict, and    mathematical principles relevant to current biological
transmissible disease. Study of each topic will involve         research, as well as for mathematically oriented students
introduction data, mathematical models, and analysis            who want to explore applications in biology. The course
techniques that build toward addressing a major question at     theme is mathematical modeling of biological processes,
each interface: Have agricultural systems been adapted to       with a special emphasis on probabilistic models and
climate change? Has drought caused conflict? And does the       inference. More than half of the course covers topics on
environment influence the spread of COVID-19? These             information theory, Bayesian inference, statistics,
questions are diverse, but are addressed using common           probabilistic modeling, and neural networks. The last
analytical frameworks. Analytical approaches include            section of the course covers dynamical systems in biology,
simple mathematical models of feedback systems, crop            including random walks, feedback control, and molecular
development, and population disease dynamics; frequentist       population dynamics. Each week-long unit is devoted to one

Rev 08/16/21                                     Course Guide for the Secondary Field in Global Health and Health Policy 10
specific topic, and is based in one or more scientific papers    between knowledge and information. This course will
selected from the recent literature. The best way to learn in    motivate statistical methods through data analysis and
this course is through the homework. They are very hands-        visualization, in addition to discussing the underlying
on, and usually require coding to implement some                 theory. We will discuss topics such as study design,
mathematical concept through a particular biological             descriptive statistics, probability, sampling distributions,
example. For instance, one unit is devoted to maximum            hypothesis testing, linear regression, and Bayesian
likelihood methods in the context of Quantitative Trait Loci     inference. A wide variety of applications from the economic
analysis; another unit explores probabilistic models in the      and social sciences will be highlighted along with examples
context of inferring ancestry and recombination breakpoints      from biology, sports, politics, and more. Students with prior
from genomic reads in fly populations. More information          exposure to introductory statistics will find some overlap of
about the course can be found at mcb111.org.                     material but be exposed to new applications and learn more
Recommended Prep: Mathematics 19 or higher.                      advanced modeling techniques. This course makes use of
                                                                 the statistical programming language R, but no prior
Psychology 1900: Introduction to Statistics for the              knowledge of computer science is required.
Behavioral Sciences                                              Course Notes: Only one of the following courses may be
Patrick Mair (Fall); TBA (Spring)                                taken for credit: Statistics 100, 101, 102, 104.
Fall; MW 9-10:15                                                 Course Requirements: Anti-Req: may not be taken for credit
Spring; TBA                                                      if STAT 109 or STAT 139 already complete.
Provides a conceptual and practical introduction to statistics
used in psychology and other behavioral sciences. Covers         Statistics 110: Introduction to Probability
basic topics in statistics including: measures of central        Joseph Blitzstein
tendency and variability; probability and distributions,         Fall; TTh 1:30-2:45
correlations and regression, hypothesis testing, t-tests,        A comprehensive introduction to probability. Basics:
analysis of variance, and chi-square tests. Includes a lab       sample spaces and events, conditional probability, and
section with instruction in statistical analysis using a         Bayes' Theorem. Univariate distributions: density functions,
computer program.                                                expectation and variance, Normal, t, Binomial, Negative
Recommended Prep: The Psychology Department requires             Binomial, Poisson, Beta, and Gamma distributions.
completion of Science of Living Systems 20 or Psychology         Multivariate distributions: joint and conditional
1 or the equivalent of introductory psychology (e.g. Psych       distributions, independence, transformations, and
AP=5 or IB=7) before enrolling in this course.                   Multivariate Normal. Limit laws: law of large numbers,
Course Requirements: Pre-requisite: SLS20 or PSY1 or             central limit theorem. Markov chains: transition
Psychology AP=5 or Psychology IB=7 or Psyc S-1                   probabilities, stationary distributions, convergence.
                                                                 Recommended Prep: Math 1b or equivalent or above.
Statistics 102: Introduction to Statistics for Life
Sciences
Kevin A. Rader
Spring; MW 12-1:15
Introduces the basic concepts of probability, statistics and
statistical computing used in medical and biological
research. The emphasis is on data analysis and visualization
instead of theory. Designed for students who intend to
concentrate in a discipline from the life sciences.
Course Notes: Only one of the following courses may be
taken for credit: Statistics 100, 101, 102, 104.

Statistics 104: Introduction to Quantitative Methods for
Economics
Kevin A. Rader
Fall; TTh 10:30-11:45
In a world where data is growing larger and more complex,
it can be a challenge to turn an abundance of information
into the knowledge from which sound decisions can be
made. As a discipline, statistics aims to bridge the gap

Rev 08/16/21                                      Course Guide for the Secondary Field in Global Health and Health Policy 11
ETHICS OF HEALTH                                                 GENED 1116: Medical Ethics and History
                                                                 David Shumway Jones
                                                                 Fall; TTh 10:30-11:45
GENED 1064: Brains, Identity, and Moral Agency                   Students will encounter the ethical dilemmas of medical
Steven Hyman                                                     practice throughout their lives, whether with their own
Spring; TTh 10:30-11:45                                          health, or with the health their families and friends. This
Advances in brain science have the potential to diminish         course will equip them with the tools of moral philosophy
many forms of human suffering and disability that are            so that they can recognize, critique, and craft arguments
rooted in disordered brain function. But what are the ethical    grounded in appeals to utilitarianism, deontology, or rights.
implications involved in altering the structure and function     But the course will focus on historical analysis of the
of human brains? What’s at stake when we have the ability        debates so that students understand how social, economic,
to alter a person’s narrative identity, create brain-computer    and political contexts have influenced moral reasoning. By
interfaces, and manipulate social and moral emotion? In this     clarifying their own thinking in the classroom, students will
course, you will ask and attempt to answer these questions,      be better equipped to engage in the debates and contribute to
and discuss the implications of mechanistic explanations of      the ongoing efforts by medicine to relieve human suffering.
decision-making and action for widely-held concepts of
moral agency and legal culpability. This course will prepare     Ethnicity, Migration, Rights 147: COVID-19, inequality
you to be a thoughtful citizen of a world characterized by       and the Latinx community
rapidly emerging understandings of human brain function,         Americo Mendoza-Mori
and by new technologies intended to repair or influence          Fall; T 3-5:45
human brains.                                                    Class Capacity: 15
Course Notes: For students who have taken MCB 80, it is          Consent Required: Instructor
contemplated that there will be a section that incorporates      When the coronavirus pandemic started to hit the world in
more advanced concepts from neurobiology.                        2020, it gave the wrong impression that it would affect
Recommended Prep: LPS A or LS 1a, a 4 or 5 on the AP             everyone the same way, acting as a ‘great equalizer’.
Biology exam, or equivalent experience in biology                However, the effects of COVID-19 exacerbated structural
                                                                 injustices and the impact varied dramatically different
GENED 1115: Human Trafficking, Slavery, and Abolition            depending on race, gender, class. According to data from
in the Modern World                                              the Centers for Disease Control and Prevention (CDC) in
Orlando Patterson                                                May 2021, Hispanics/Latinos were twice as likely to get the
Spring; TTh 1:30-2:45                                            virus in comparison to white adults, and 2.3 times more
We often think of slavery as being a dark chapter in our         likely to die from it. Even as vaccines have become
past, but this is a tragic oversimplification. What defines      available, their distribution has also been affected by
slavery in the modern world, and what are the moral,             disparities of access.
political and social implications of its continued existence?    For this class we will analyze discursivities that have been
As we explore its underpinnings, we discover that all of us      exposed by the pandemic and have since become topics of
may be in some way complicit in its survival. This course        ethical and social reevaluation: health disparities, the
surveys the nature, types and extent of modern servitude         distribution of labor, housing and transportation, language
such as transnational and domestic prostitution, forced          access, environmental racism (including activism against
marriage, labor trafficking and forced domestic labor, child     anti-Asian and anti-Black violence). At the same time, we
soldiering and other forms of enslavement of children, organ     will explore public policy and solidarity grassroot initiatives
trafficking and other health aspects of trafficking, debt-       that have provided community support and programmatic
bondage, and the forced exploitation of other vulnerable         responses on healthcare, social and racial justice, and
groups such as refugees and stateless persons. Throughout        climate issues to the future of US society.
the course, but especially in the final part, we examine anti-   Community testimonies and guest speakers, multimedia
trafficking and anti-slavery measures and movements and          content, interdisciplinary readings, and class debates are
ways in which you can increase awareness or become               intended to encourage reflection and to learn from
involved. You will, by the end of our exploration, be able to    underrepresented voices of the pandemic. This is a speaking
trace the moral and ethical arguments surrounding human          seminar, open to all students, that will promote oral
slavery in its various forms, understand the ways in which       communication and critical thinking skills through
this problem still affects so many people, and what can and      discussions, projects, and prepared presentations.
should be done about it.

Rev 08/16/21                                      Course Guide for the Secondary Field in Global Health and Health Policy 12
Global Health and Health Policy 70: Global Response to          History of Science 2953: Bioethics, Law, and the Life
Disasters and Refugee Crises                                    Sciences
Stephanie Kayden, Michael VanRooyen                             Sheila Jasanoff
Spring; Th 12:45-2:45                                           Spring; TBA
Class Capacity: 30                                              Class Capacity: 30
Consent Required: Instructor                                    Consent Required: Instructor
Climate change, urbanization, and conflict mean that global     Seeks to identify and explore salient ethical, legal, and
disasters are on the rise. How should the world respond         policy issues - and possible solutions - associated with
when disasters force people from their homes? How can we        developments in biotechnology and the life sciences.
better help the world’s refugees? This course examines the      Course Notes: Offered jointly with the Kennedy School as
past, present, and future of the international humanitarian     IGA-515. Cannot be taken for credit by students who have
response system. We will explore how Doctors Without            already taken IGA-515.
Borders, the United Nations, the Red Cross, and other aid
agencies came to be and how global response standards,          Sociology 1106: Humanitarian Activism and Civil
international humanitarian law, and new technologies are        Society
shaping worldwide disaster relief.                              Shai Dromi
Through interactive discussions and case studies, students      Spring; TTh 9-10:15
will learn how aid workers interact with governments,           When global crises strike, humanitarian nongovernmental
militaries, and civil society to provide refugee aid. At the    organizations – NGOs – spring to action, offering
end of the course, students can choose to live the refugee      emergency medical services, basic necessities, expertise,
experience during a large-scale, weekend outdoor simulated      and innovation to affected communities around the world.
humanitarian response training program together with other      Yet COVID-19 brings unprecedented challenges—and
students and professional aid workers from around the           unprecedented opportunities—to humanitarian endeavors.
world.                                                          Humanitarian workers are now working globally to
Course Notes: Lotteried course, enrollment limited to 30.       distribute personal protection equipment in disadvantaged
                                                                communities, trace the spread of coronavirus in countries
Government 94gk: The Politics and Ethics of Medical             with sparse public health resources, support countries with
Care                                                            weakened hospital systems, and advocate for an equitable
Gabriel Katsh                                                   distribution of a future vaccine.
Fall; Th 3-5:45                                                 This course provides a comprehensive view of humanitarian
Class Capacity: 16                                              organizations and activism from a sociological perspective.
Consent Required: Instructor                                    We will examine the origins of organized humanitarian
This course is an introduction to medical ethics and the        activism and the dilemmas and challenges that NGOs face.
ways in which political theory can inform our understanding     We will investigate the consequences, justifications, and
of the moral and political dimensions of medical care. Using    limitations of humanitarian work. COVID-19 will be a
case studies as a launching point, we will explore ideas        central study case for us, and we will also look at case
about autonomy, paternalism, beneficence, and distributive      studies from the Kosovo War, the Nigerian Civil War, and
justice, and their application to issues such as informed       the 2004 Indian Ocean Tsunami. Students will be assigned
consent, medical privacy, and the right to refuse care. The     specific regions to research over the course, and will create
Fall 2021 iteration of the course will focus in particular on   visual representations of the conditions and humanitarian
ethical and policy dilemmas that have arisen in the context     activities in their assigned region. The course will include a
of the coronavirus pandemic, including questions about the      virtual “hackathon” with the Bok Center's Learning Lab
distribution of scarce resources, the health effects of         Studio where students will learn visual media skills for this
inequality, and balancing the needs of public health with       purpose.
concerns about individual liberty. Readings include classics
of moral and political philosophy, writings by contemporary     Sociology 1131: Philanthropy and Nonprofit
medical ethicists, Supreme Court decisions, and some            Organizations
empirical and historical studies.                               Shai Dromi
                                                                Fall; MW 3-4:15
                                                                Class Capacity: 50
                                                                Consent Required: Instructor
                                                                When crises strike, nonprofit organizations spring to action,
                                                                offering their resources, expertise, and innovation to

Rev 08/16/21                                     Course Guide for the Secondary Field in Global Health and Health Policy 13
affected communities. Yet COVID-19 brings unprecedented           policies, programs and interventions. The course clarifies
challenges—and unprecedented opportunities—to                     how human rights approaches complement and differ from
philanthropic endeavors. Indeed, aside from supporting            those of bioethics and public health ethics.
medical research on COVID-19, nonprofit organizations             Among the issues to be considered from a human rights
have been providing medical care, distributing personal           perspective are the bioethics, torture prevention and
protective equipment (PPE), helping address loss of               treatment, infectious diseases, violence prevention and
employment and food insecurity, and advocating for global         responses, genetic manipulation, access to affordable drugs,
equity in vaccine distribution, among other tasks.                community-based health management and financing, child
This course partners with the Lemann Program on                   labor, aging, and tobacco control.
Creativity and Entrepreneurship (LPCE) in order to provide        Course requirements are active participation in class
students with a unique opportunity to experience first-hand       discussion (25%), presentation of a paper (10%) and quality
how philanthropists and nonprofit organizations are helping       of the term paper (65%).
address the global effects of this global pandemic. On the        Course Requirements: Students outside of HSPH must
theoretical side, the course will examine the workings of         request instructor permission to enroll in this course.
philanthropy and of nonprofit organizations, using different      Note: This course provides 2.5 credits. In order to receive
sociological perspectives and a series of case studies.           credit equivalent to a course in FAS, a student must take
Alongside the theoretical content, students will form groups      two 2.5-credit HSPH courses.
and will develop their own nonprofit ventures to address the
social impact of COVID-19. Student ventures will receive          XREG: HSPH ID 250: Ethical Basis of the Practice of
startup seed funding and, at the end of the course, will          Public Health
compete over additional seed money. The course will               Daniel Wikler Ole Norheim
include a series of guest lectures and workshops on               Fall 1; MW 8-9:30am
entrepreneurship to support student venture development.          Class Capacity: 37
                                                                  This course serves as an introduction to ethical issues in the
XREG: HSPH GHP 265: Ethics of Global Health Research              practice of public health. Students will identify a number of
Richard Cash                                                      key ethical issues and dilemmas arising in efforts to improve
Spring 2; MW 3:45-5:15                                            and protect population health and will become familiar with
Class Capacity: 50                                                the principal arguments and evidence supporting contesting
This course is designed to expose students to the key ethical     views. The class aims to enhance the students' capacity for
issues that may be encountered in the course of conducting        using ethical reasoning in resolving the ethical issues that
global health research. Using case presentations and              will arise throughout their careers.
discussion-based class sessions, students will have the           Unlike courses in medical ethics, which mainly examine
opportunity to begin developing their own tools for dealing       ethical dilemmas facing individual clinicians, the
with these important issues in an applied context.                population-level focus of this course directs our attention to
Course Note: Required for GHP SM2 research students.              questions of ethics and justice that must be addressed at the
Course is Restricted: GHP SM2 research students. Seats            societal level. These include: What social response is
will be made available to other students if room is available.    required of a just society to the needs of its members for
Students outside of HSPH must request instructor                  protecting and restoring health? Is population health
permission to enroll in this course.                              something other than the aggregate of the health concerns of
Note: This course provides 2.5 credits. In order to receive       the individuals who make up a society at a given time? And
credit equivalent to a course in FAS, a student must take         what are the ethical implications of the answers? When are
two 2.5-credit HSPH courses.                                      inequalities in health inequitable, and what priority should
                                                                  be assigned to reducing disparities in health when pursuing
XREG: HSPH GHP 288: Introduction to Health and                    this goal might compromise the effort to maximize
Human Rights                                                      population health? Which ethical choices, if any, are
Stephen P. Marks                                                  unavoidable in developing the methodologies for
Fall 2: MW 2-3:30                                                 measurement of health and of the global burden of disease?
Class Capacity: 32                                                Which ethical choices if any are unavoidable in developing
The aim of this course is to introduce students to the            and using methods for priority-setting such as cost-
application of the human rights framework to a wide range         effectiveness analysis and cost-benefit analysis? Are the
of critical areas of public health. Through lectures, cases and   ethical commitments of the profession of public health
guest speakers, students will become familiar with the            consistent with some methods and not others? Should the
human rights perspective as applied to selected public health     institution of universal health coverage be guided by ethical

Rev 08/16/21                                      Course Guide for the Secondary Field in Global Health and Health Policy 14
precepts and if so, what are these values and how should
they guide policy? Can and should public health's dedication
to improving population health conflict with the priorities of
some individuals whose choices to not reflect such high
priority for health? Should these individual preferences
always be respected? Are there effective strategies that
pursue population health in the face of such conflicts while
preserving the individual's freedom to make unhealthy
choices? How should responsibility for poor health be
assigned, and what are the ethical implications of this
assignment for poor health due to health problems due to
smoking, obesity, and other unhealthy behavior? To the
extent that the socio-economic health gradient reflects
differences in how well people take care of themselves are
these disparities in health individual failings rather than
social injustices?
Class Notes: A course materials fee may apply for this
course. An upper estimate is listed below, and the final
materials fee will be communicated to enrolled students at
the beginning of the term. For more information and a list of
past years' materials fees for the current semester's courses,
please visit the Curriculum Center website. [Estimated Non-
Textbook Course Material Fee:< $25]
Course Requirements: Students outside of HSPH must
request instructor permission to enroll in this course.
Note: This course provides 2.5 credits. In order to receive
credit equivalent to a course in FAS, a student must take
two 2.5-credit HSPH courses.

Rev 08/16/21                                      Course Guide for the Secondary Field in Global Health and Health Policy 15
HEALTH AND DEMOGRAPHY                                             Course Notes: Students who complete GHHP 30 may apply
                                                                  to participate in an experiential learning opportunity in San
                                                                  Vito, Costa Rica over spring break. Since slots are limited,
GENED 1063: World Health: Challenges and                          there will be a lottery.
Opportunities
Sue J. Goldie                                                     Sociology 1046: Life and Death by Design
Spring; MW 10:30-11:45                                            Jason Beckfield
Class Capacity: 200                                               Fall; MW 10:30-11:45
Consent Required: Instructor                                      In this course, we will study health differences between
Extraordinary changes in the world present both risks and         social groups. We will begin by examining the extent to
opportunities to health—unprecedented interconnections            which health is unevenly distributed across groups defined
across borders, rapidly shifting global demographics, and         by nationality, neighborhood, race, gender, and class -
changing patterns of diseases and injuries. This course will      differences highlighted in stark terms by the COVID-19
challenge your assumptions about the world’s populations,         pandemic. We will then seek to pinpoint the reasons for
as you discover surprising similarities and unexpected            these disparities with a detailed analysis of the pathways
differences between and within countries. Approaching the         through which these factors are linked to health status.
concept of health as a fundamental prerequisite for building      Finally, we will discuss new research on the sociology of
strong societies, we will explore its connection to human         population health that shows how health disparities depend
rights, international relations, and sustainable development.     on meso- and macro-scale causes like neighborhoods, social
Using case examples of contemporary health challenges, we         policy arrangements, global organizations, and climate
explore the influence of social, political, and environmental     change.
determinants on health, particularly transnational risks          Course Notes: May be used as an introductory course when
associated with globalization. We consider solutions from         taken for letter grade, or elective.
an array of perspectives, contributions from within and
outside the health sector, and interventions at the local,
national and global levels. By the end of the course, you will
be equipped to thoughtfully analyze important health
challenges and appreciate how evidence is contextualized
and translated to policy and action.

Global Health and Health Policy 30: Global Oral Health:
Healthy Teeth, Healthy Societies
Brittany Seymour
Fall; MF 10:30-11:45
Class Capacity: 34
Consent Required: Instructor
Did you know that one of the strongest indicators of a
healthy society is the health of its teeth? Everyone has teeth,
but most people in the world don’t have access to affordable
dental care. This discussion-based course assesses current
global health policies and approaches for addressing
pressing health challenges despite resource constraints and
severe political neglect. It aims for students to be competent
in incorporating the global burden of oral diseases into
foundational concepts of global health and world
development. These include how oral diseases are
associated with globalization, poverty, infectious and non-
communicable diseases, maternal and child health, mental
health, nutrition, tobacco, alcohol, urban and rural
infrastructures, climate change, and the environment. This
course demonstrates how complete health and an end to
global poverty are not possible without including oral health
in the global health and development agenda.

Rev 08/16/21                                       Course Guide for the Secondary Field in Global Health and Health Policy 16
HEALTH, CULTURE, AND SOCIETY                                    Freshman Seminar 25n: Finding Connections:
                                                                Perspectives on Psychological Development and Mental
                                                                Illness
Freshman Seminar 23k: Insights from Narratives of               Nancy Rappaport
Illness                                                         Fall; W 3-5
Jerome Groopman                                                 Class Capacity: 12
Spring; M 12:45-2:45                                            Consent Required: Instructor
Class Capacity: 12                                              The seminar's challenge will be to deepen our understanding
Consent Required: Instructor                                    of human development and how individuals cope with
A physician occupies a unique perch, regularly witnessing       serious emotional or social difficulties (neglect, bipolar
life’s great mysteries: the miracle of birth, the perplexing    disorder, autism, depression, schizophrenia). We will use
moment of death, and the struggle to find meaning in            multiple perspectives: medical observations and texts that
suffering. It is no wonder that narratives of illness have      provide practical knowledge (e.g. The New England Journal
been of interest to both physician and non-physician writers.   of Medicine review articles), narrative readings to
This seminar will examine and interrogate both literary and     understand how patients experience the meaning of illness
journalistic dimensions of medical writing. The                 from the inside out (e.g. The Center Cannot Hold), visitors
investigation will be chronological, beginning with “classic”   who will discuss their experience with mental illness, and
narratives by Tolstoy, Chekhov, and Kafka, and then             how development-related mental illness is portrayed in the
moving on to more contemporary authors such as William          press (e.g. The New Yorker articles). We will start with the
Carlos Williams, Richard Selzer, Oliver Sacks, Susan            mental life of babies and how scientists interpret infants’
Sontag, and Philip Roth. Controversial and contentious          nonverbal ways of finding safety and security. This begins
subjects are sought in these writings: the imbalance of         the journey of our understanding fundamental needs for
power between physician and patient; how different              tenderness, holding, and making meaning. Understanding
religions frame the genesis and outcome of disease; the role    how conditions such as autism, depression, and
of quackery, avarice, and ego in molding doctors’ behavior;     schizophrenia are described in clinical research and
whether character changes for better or worse when people       literature will help us to appreciate the biological
face their mortality; what is normal and what is abnormal       vulnerabilities and relational patterns that may disrupt the
behavior based on culture, neuroscience, and individual         human connection. We will examine the resourcefulness
versus group norms. The presentation of illness in              required for both fragility and resiliency. Throughout the
journalism will be studied in selected readings from the New    seminar, the instructor, as a practicing child and adolescent
York Times’ and Boston Globe’s Science sections, as well as     psychiatrist, will bridge the gap between research findings,
periodicals like the New Yorker, The New York Review of         clinical applications, and everyday insight.
Books, Harper’s, and the Atlantic Monthly. The members of       Course Requirements: Course open to Freshman Students
the seminar will analyze how the media accurately present       Only.
the science of medicine or play to “pop culture.” The
seminar will study not only mainstream medical journalists,     Freshman Seminar 71O: The Heart of Medicine: Patients
but so called alternative medical writers such as Andrew        & Physicians & Experience of Serious Illness in the Age
Weil and celebrity health voices like Gwyneth Paltrow.          of COVID-19
Patients with different diseases will be invited to speak to    Susan Block
the members of the seminar about their experiences.             Fall; W 3-5
Students will try their hands at different forms of medical     Class Capacity: 12
writing, such as an editorial on physician-assisted suicide     Consent Required: Instructor
that would appear in a newspaper and a short story that         Sickness and death are universal human
describes a personal or family experience with illness and      experiences. Although the COVID-19 pandemic has
the medical system.                                             brought this reality home, in many difficult ways, to all of
Course Requirements: Course open to Freshman Students           us over the past 2 years, thinking about our own losses and
Only.                                                           vulnerability and that of people we love is often
                                                                uncomfortable. This terrible year has also created many
                                                                opportunities for us to grow, as individuals and as a
                                                                society. Building on our collective experiences of the past
                                                                year, we will explore our own perspectives and experiences
                                                                with serious illness and death; examine the vulnerabilities in
                                                                our health system and our society that also contribute to the

Rev 08/16/21                                     Course Guide for the Secondary Field in Global Health and Health Policy 17
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