Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust

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Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Barts Health
                                                    NHS Trust

Patient information

Skin care after
an organ transplant
Also for those who have
a suppressed immune system

Dermatology Department
The Royal London Hospital

Please bring this booklet with you to all clinic visits
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Contents

                                               Introduction.............................................................................................................................4
The production of this updated skin care
booklet was developed as part of a             About the transplant skin clinic.........................................................5–7
Mary Seacole Award
                                               Common skin conditions after transplant..................... 8–29
                                               List of conditions......................................................................................................................8

                                               Skin cancer prevention......................................................................... 30–35
     BSSCII
      British Society for Skin Care
                                               Skin self-examination...........................................................................................30–32
      In Immunosuppressed Individuals
                                               Body diagrams....................................................................................................................... 33
Endorsed by the British Society for            Sun protection and vitamin D...................................................................... 34–35
Skin Care in Immunosuppressed Individuals
(BSSCII)
                                               Further information................................................................................................. 36

                                               Dermatology Department contact numbers.................... 37

                                               Patient diary............................................................................................................38–39
The original skin care booklet was funded by
Barts Charity

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Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Introduction                                                        About the transplant skin clinic
    After an organ transplant you will need to take                     The transplant skin clinic is part of the Dermatology
    immunosuppressive (anti-rejection) drugs which suppress your        Department at Barts Health NHS Trust. Located on the
    immune system and help to prevent your organ being rejected.        second floor of The Royal London Hospital, it is run by
    These medicines mean that you are more likely to suffer from        dermatologists for monitoring, preventing and treating skin
    certain skin conditions as you are less able to fight infections.   problems in patients who have had an organ transplanted or
    Immunosuppressive drugs can also increase your risk of              who are immunosuppressed for other reasons. It is one of the
    developing some skin cancers, depending on the type of skin         biggest centres for this specialty in the UK.
    that you have.
                                                                        Doctors and specialist nurses from the clinic aim to see you
    This booklet has been produced to help you look after your          routinely following your transplant to alert you to any possible
    skin following an organ transplant. Much of the advice is also      skin problems that might arise, and to assess your individual
    appropriate for people who have a suppressed immune system          risk for skin cancer. They will give you advice and guidance
    due to other causes such as chronic lymphocytic leukaemia           on how to look after your skin.
    (CLL) and HIV, and for those awaiting an organ transplant.
                                                                        Depending on your risk factors and individual needs, you will
    The booklet gives you information about what signs and              be advised how frequently you need to be seen thereafter –
    symptoms to look out for, and describes the treatment for a         usually between one and five years.
    variety of skin conditions. There is also a useful chapter on
    skin cancer prevention including how to examine your skin and       An important part of the work of the clinic is the study of skin
    protect yourself from exposure to the sun.                          disease and skin cancer after a transplant, with a view to
                                                                        preventing and improving treatment for these conditions.
    At the back is a patient diary for you to write down the outcome    We may ask you whether you would be willing to participate
    of your clinic visits and any comments about your skin condition.   in one of the research studies being undertaken by the clinic.
    Please bring this booklet with you when you come to the
    transplant skin clinic.

4                                                                                                                                          5
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
How often will I be seen in the clinic?                            Follow-up appointments
    This will depend upon your risk of developing skin problems.       For some of you the risk of developing skin problems is so low
    Our aim is to detect new or suspicious skin lumps early so that    that we will not need to see you routinely. We ask only that
    we can treat them as soon as possible.                             you self-examine your skin and request a referral back to us if
                                                                       there are any concerns.
    At your first appointment we will assess your risk of developing
    skin cancer. This is based on:                                     Other patients need to be seen at regular intervals. This may
                                                                       be as little as once every five years, every 18 months or as
    • Your age                                                         much as every three months. We will let you know when your
    • Your age at transplantation                                      appointments should be made.

    • How easily you burn in the sun                                   The frequency of your visits may change over the course of
                                                                       your care. If you develop a skin cancer you will need to be
    • Your history of sun exposure                                     seen more often.
    • How often you have suffered sunburn
    • Any pre-existing skin problems                                   Between appointments
                                                                       For everyone regular self-examination of the skin is essential
                                                                       so that problems, especially skin cancer, can be detected
                                                                       early and treated. How to examine your skin is described on
                                                                       pages 30–32.
                                                                       If you have a skin lesion that changes over time, or develop a
                                                                       new skin mark, please ask a health professional for advice or
                                                                       ring us. Our contact numbers are on page 37.

6                                                                                                                                        7
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Common skin conditions after a transplant                                                                                                  Delayed wound healing and fragile skin
These are the skin conditions most commonly seen after transplant                                                                          Some patients may notice thinning of the skin with increased bruising.
surgery. Each of these skin problems is described with a photograph                                                                        This is usually due to medication, in particular the use of steroids.
on the pages shown below. Do look through them to familiarise                                                                              Cuts and abrasions may take longer to heal.
yourself with the skin conditions.
       Delayed wound healing and fragile skin............................... 9
                                                                                                                                           Acne
       Acne ...................................................................................................................... 9
                                                                                                                                           Spots are common in the first 12–18 months after transplantation,
       Sebaceous gland hyperplasia..................................................... 10                                                 particularly in younger patients. They usually settle down as the
       Fungal infection of the skin and nails.......................... 11–13                                                              dosage of immunosuppressive drugs is lowered.

       Pityriasis versicolor (yeast infection)..................................... 14                                                     Treatment for acne
       Other infections............................................................................... 15–16                               Creams or gels may be all that is needed. Some of these can be
                                                                                                                                           obtained from a pharmacy and others can be prescribed by your GP.
       Viral warts...................................................................................................... 17
       Benign (harmless) skin lumps........................................... 18–19                                                       If creams or gels do not control the acne, antibiotics may be required
                                                                                                                                           from your GP or dermatologist. For very severe acne a dermatologist
       Pre-cancerous skin lesions.................................................20–22                                                    may prescribe tablets such as isotretinoin.
       Skin cancer.......................................................................................... 23–29

Throughout this booklet any skin condition
                                 condition that requires urgent                                                                                    Acne on
medical assessment has been indicated by a red asterisk
                                                 asterisk                                                                                        the cheek
                                                                                                                                       ]
If you develop any skin problem that you are worried about you can:
•	Contact the Dermatology Department
•	Speak to one of the transplant nurses if your transplant was
   carried out at this Trust
•	Make an appointment with your GP
• Call NHS 111 if you are feeling very unwell
•	Go to your local A&E department if your symptoms are severe

8                                                                                                                                                                                                                   9
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Sebaceous gland hyperplasia (SGH)                                        Fungal infection of the skin and nails
SGH is very common after an organ transplant. As shown in
the photograph, it appears as small (2–4mm in diameter), raised,         Fungal infection of the skin on the feet
whitish/yellowish bumps on the skin, especially on the forehead,         (tinea pedis or athlete’s foot)
nose and cheeks.                                                         This is a very common condition that usually appears as scaly patches
                                                                         on the feet and a red/white rash between the toes, both of which can
Treatment for SGH
                                                                         be itchy.
This is a benign condition and usually no treatment is required unless
the appearance of SGH is a significant cosmetic problem.                 Treatment for athlete’s foot
                                                                         Creams are available over the counter from your pharmacist or can be
                                                                         prescribed by your GP.

      Sebaceous                                                             Athlete’s foot
            gland
      hyperplasia
     on the cheek

10                                                                                                                                          11
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Fungal infection of the skin elsewhere                                Fungal infection of the nails (onychomycosis)
(tinea corporis or ringworm)                                          Infection first appears as yellow or white patches under and within
This appears as red, scaly, itchy patches on the body. It can         a toenail; it can push the nail up off the bed and cause the nail to
start anywhere but is especially common on the trunk and in           become thicker. The infection usually starts in one toenail and then
the groin region.                                                     spreads to the others.

Treatment for ringworm                                                Treatment for onychomycosis
It is important to have a diagnosis from a doctor before beginning    You may be given a lacquer (nail paint) by your GP but if your nails
treatment so if you think you have ringworm contact your GP in        are very thick this can take up to a year to remove the infection.
the first instance. Treatment is usually the application of a cream   For severe infection you may need a course of tablets from your
or shampoo.                                                           dermatologist to be taken over several months.

      Ringworm                                                                 Fungal
     on the arm                                                            infection of
                                                                          the toenails

12                                                                                                                                           13
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Pityriasis versicolor (yeast infection)                                Other infections
This common yeast infection of the skin often affects the chest and
back. It usually appears as pink or brown patches, darker or lighter   Shingles and chickenpox (herpes zoster and varicella)]
than your normal skin tone, and may be scaly and itchy.
                                                                       Shingles and chickenpox are caused by the same virus. Both
Treatment for yeast infection                                          can be more serious in people who have had a transplant.
Treatment usually involves washing with an anti-fungal shampoo and     Shingles usually appears as a painful, blistering rash on a particular
using an anti-fungal cream for several weeks which can be obtained     area of the body, for example one side of the chest, the arm or on
from your GP.                                                          one side of the face. Chickenpox is usually associated with feeling
Sometimes it may be necessary to see your dermatologist who can        unwell and a more widespread rash which eventually blisters.
prescribe an anti-fungal tablet as well.                               Treatment for shingles and chickenpox
                                                                       Treatment mainly involves antiviral medication but it is not
                                                                       always required.

        Pityriasis                                                         Shingles on
       versicolor                                                         the right side
     on the back                                                            of the back

                                                                                           If you think you may have developed either
                                                                                   ]       shingles or chickenpox, especially if you have any
                                                                                           form of blistering rash, you should seek medical
                                                                                           attention immediately. Both are contagious and
                                                                                           people with shingles can cause chickenpox in
                                                                                           those who have not previously had it.

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Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Cold sores (herpes simplex)                                               Viral warts
The herpes simplex virus causes cold sores which are very common          These are very common after transplantation and are caused by
but they may be more of a problem after a transplant. They usually        the human papillomavirus (HPV). Some people develop just one
appear as painful blisters or ulcers that come back in the same part of   or two warts – often on the hands or feet – while others can develop
the body such as on the lips, nose or buttocks.                           large numbers that need specialist care. On the feet they are
                                                                          known as verrucas.
Treatment for cold sores
Cold sores may need treatment with antiviral creams available over        Treatment for viral warts
the counter from a pharmacist. If they are still causing a problem go     Warts and verrucas can be difficult to treat in organ transplant patients
to your GP, who might prescribe tablets, and if they become very          but your GP or dermatologist will usually recommend a salicylic acid
troublesome contact your dermatologist.                                   preparation such as Verrugon or Occlusal.
                                                                          If one or more of these treatments don’t work, more aggressive
                                                                          therapy such as freezing (cryotherapy) or other creams may be
                                                                          recommended.

     Cold sore in                                                                    Warts
        the nose                                                               on the toes
                                                                               and fingers

16                                                                                                                                               17
Skin care after an organ transplant - Patient information Dermatology Department The Royal London Hospital - Barts Health NHS Trust
Benign (harmless) skin lumps

Seborrhoeic warts (seborrhoeic keratoses)                             Campbell de morgan spots (cherry angiomas)
These are harmless lesions with a warty appearance although           These are harmless overgrowths of blood vessels and do not require
they are not warts and are not caused by a virus like true warts.     treatment. They look like tiny, red, raised spots and are common on
Seborrhoeic warts often appear on the back and chest but they can     the chest and abdomen, but can appear on any part of the body.
erupt anywhere on the skin, and there may be many of them.

Treatment for seborrhoeic warts
Seborrhoeic wards do not usually require treatment but if they are
causing problems the warts can be frozen off or removed surgically.

     Seborrhoeic                                                         Campbell de
            wart                                                        morgan spots

18                                                                                                                                      19
Pre-cancerous skin lesions

Actinic keratosis (AK)                                                  Bowen disease (carcinoma in situ)
This is also known as solar keratosis as it tends to occur on           Bowen disease, or squamous cell carcinoma in situ (CIS), is
sun‑exposed sites such as the hands, face and scalp. It appears as      commonly found on the lower legs, hands, forearms and face.
small, dry, flaky patches of skin, some of which can have a crust.      It appears as crusty/scaly areas of reddened skin which can
Sometimes this crust can fall off leaving a red area underneath.        sometimes ulcerate. These areas can range in size from small lesions
                                                                        the size of a pea to large areas almost covering the back of a hand.
Solar keratosis is usually painless but may be slightly itchy. If you
develop any tenderness or pain in the area you should seek medical      The presence of Bowen disease may be a sign that you are at
advice from your dermatologist.                                         increased risk of skin cancer, and these lesions have the potential
                                                                        to develop into skin cancer.
The presence of actinic keratosis may be a sign that you are at
increased risk of skin cancer, and the condition has the potential      If you suspect the condition please contact the Dermatology
to develop into skin cancer. It is usually assessed and treated, if     Department for advice.
necessary, within the Dermatology Department.
                                                                        Treatment for Bowen disease
Treatment for actinic keratosis                                         Bowen disease is usually assessed, diagnosed and treated within the
Treatment includes the following options:                               Dermatology Department.
• Observation (watchful waiting)
• Freezing (cryotherapy)               • Aldara (imiquimod) cream
• Solaraze (hyaluronic acid) gel       • Surgical removal
• Efudix (5-fluorouracil) cream        • Photodynamic therapy (PDT)

                                                                                 Bowen
         Actinic                                                                disease
       keratosis

20                                                                                                                                            21
Porokeratosis                                                         Skin cancer
Porokeratosis appears as raised, sometimes scaly, red rings or        These four types of skin cancer are most commonly seen after an
patches which are often found on the lower legs.                      organ transplant:
Very rarely porokeratosis can develop into skin cancer, so if you     • Squamous cell carcinoma (SCC)
suspect that you have the condition let your dermatologist know at
your next appointment.                                                • Basal cell carcinoma (BCC)
                                                                      • Melanoma
Treatment for porokeratosis
                                                                      • Kaposi sarcoma (KS)
Porokeratosis is usually assessed, diagnosed and treated within the
Dermatology Department.                                               The main cause of skin cancer is a combination of exposure to the
                                                                      sun, which may have happened many years earlier, and
                                                                      immunosuppressive drugs used to stop the transplanted organ from
 Porokeratosis                                                        being rejected.
  on the lower
           leg
                                                                      The major risk factors for skin cancer are:
                                                                      •	The length of time you have had your transplant: the longer you
                                                                         have had your transplant, the greater the risk
                                                                      • Receiving your transplant after the age of 50 years
                                                                      • Having light skin which burns easily and freckles in the sun
                                                                      • High levels of sun exposure in the past
                                                                      •	Having a precancerous lesion such as actinic keratosis,
                                                                         Bowen disease or porokeratosis

22                                                                                                                                         23
Squamous cell carcinoma (SCC)]
Squamous cell carcinoma is the most common skin cancer in
transplanted patients, especially those with fair skin.                         Squamous
                                                                                      cell
SCCs appear as red, crusty, raised lumps, bumps or ulcers.                     carcinomas
Sometimes they may look like warts with a red base. They can be
tender or painful and they may bleed. SCCs can grow quite quickly,
for example double in size within two to three months, but this is not
always the case.
SCC is most common on areas of the body that are regularly exposed
to the sun, such as the face, ears, hands, and lower legs in women.
Transplant patients will often go on to develop more SCCs after the
first one appears.
People from South Asian or African/Afro-Caribbean backgrounds are
at a lower risk of SCC, but it may still occur – particularly in the genital
region. If you see any non-healing lumps or bumps in this area you
should let your dermatologist know.

Treatment for squamous cell carcinoma
There are four treatment options:
1. S
    urgical removal. These lesions can usually be removed by surgery
   in the Dermatology Department. If the skin cancer is big, or in
   a difficult area such as the ears or eyes, plastic surgery may be
   necessary combined with skin grafting. If left to grow, SCC can
   infiltrate deeper and spread to the lymph glands.
2. R
    adiotherapy. This is occasionally used as an alternative, or in
   addition, to surgery.
                                                                                             If you think that you may have a squamous cell
3. A
    reduction in immunosuppressive drugs. Sometimes organ
   transplant patients can develop multiple squamous cell carcinomas.                 ]      carcinoma, telephone either of the Dermatology
                                                                                             Department contact numbers listed on page 37
   If this occurs the dermatologists may find out from the transplant
   doctors whether it would be possible to reduce the dose of                                as you will need to see a dermatologist.
   immunosuppressive drugs.
4. A
    citretin. In some cases a drug called acitretin may be prescribed
   to slow down and prevent the development of these skin cancers.
24                                                                                                                                            25
Basal cell carcinoma (BCC)]                                             Melanoma]
Basal cell carcinoma lesions usually appear as shiny/pearly lumps       Melanoma is an uncommon tumour in organ transplant patients but it
and are commonly found on the upper body and face, but they can         is important to catch it early as melanoma can spread. Melanoma can
develop elsewhere. Occasionally they appear as crusting, sore areas     arise from a longstanding mole, or from a new mole that wasn’t
of skin that do not heal. The majority grow slowly and can take up to   there before.
a year to double in size.
                                                                        If you notice any change in the shape, size, or colour of a
Treatment for basal cell carcinoma                                      longstanding mole, or if you develop a new mole, it should be
The treatment options are:                                              examined by a dermatologist.

• Surgery                                                               In people with darker skin, melanoma is more commonly seen under
                                                                        the nails and on the feet
• Aldara (imiquimod) cream or Efudix (5- fluorouracil) cream
• Cryotherapy                                                           Treatment for melanoma
• Radiotherapy                                                          Melanoma is usually treated with surgery in the first instance.

       Basal cell                                                            Melanoma
     carcinomas

                    If you think that you may have a basal cell                           If you think that you may have melanoma,
            ]       carcinoma, telephone eithery of the Dermatology
                    Department contact numbers listed on page 37
                                                                                    ]     telephone either of the Dermatology Department
                                                                                          contact numbers listed on page 37 as you will
                    as you will need to see a dermatologist.                              need to see a dermatologist.

26                                                                                                                                         27
Kaposi sarcoma (KS)]
People from Africa, the Middle East, the Mediterranean and
Caribbean have a higher risk of developing a type of skin cancer                 Kaposi
known as Kaposi sarcoma. It is caused by human herpes virus                 sarcoma on
(HHV8), which is very common in these areas.                                  the ankle
                                                                               and shin
The virus is often picked up in childhood and lies dormant in the body
but can be reactivated when the immune system is suppressed with
immunosuppressive drugs. This sarcoma can appear at any time
after a transplant but usually develops in the first three to five years.
Most often KS appears on the skin but it can also affect organs
inside the body such as the lymph nodes, lungs, the bowels or
inside the mouth. Changes on the skin appear as small, flat areas
of discolouration, spots, or larger, raised bumps or ulcers. Colours
range from red, brown and purple to deep purplish blue. To confirm
the diagnosis a skin biopsy, a small piece of skin removed under local
anaesthetic, is taken from the lesion.
Other symptoms can occur before any skin lesions appear; one of the
commonest is swelling in one leg. There may be swelling of the arms
and legs accompanied by pain if the lymph nodes are involved. It is
important to have these symptoms investigated by the Dermatology
Department as soon as possible.

Treatment for Kaposi sarcoma
Sometimes all that is needed is a reduction or change in
immunosuppressive drugs; this can take several months to have
an effect.
Additional treatments such as surgical removal of the lesion,                             If you think that you may have Kaposi sarcoma,
radiotherapy and chemotherapy are occasionally required.                           ]      telephone either of the Dermatology Department
                                                                                          contact numbers listed on page 37 as you will
If you have had a transplant, decisions on treatment for KS will be
made in consultation with your transplant doctors as it is important to                   need to see a dermatologist.
monitor the function of the transplant organ throughout treatment.

28                                                                                                                                         29
Skin cancer prevention                                                     • A tape measure or ruler

It is important that you can recognise the early signs of skin cancer so   •	A digital camera or mobile phone to record any skin marks that you
that the appropriate treatment can be given. The earlier these skin           are not sure about
growths are detected, the better the outcome.                              To make sure that you check all your skin, we suggest you examine
                                                                           yourself from head to toe following these steps. Use a mirror to check
                                                                           difficult-to-see areas or ask a friend or relative to help you.
Skin self-examination
                                                                           Head
We recommend you examine your skin regularly, ideally at least once
                                                                           Beginning with your head, examine your scalp using a comb to part
a month. This means that if you notice any new lumps, bumps, marks
                                                                           your hair so you can check all over your scalp. Go on to look over your
or growths on your skin they can be checked by a dermatologist and,
                                                                           face and neck. Don’t forget to check behind your ears and the back of
if necessary, treated early. Early detection can help to reduce the risk
                                                                           your neck.
of developing a larger, more serious skin cancer that may need
extensive surgery or treatment.
                                                                           Upper body
You should be looking for:                                                 Check your shoulders, chest and abdomen, again using a comb to
                                                                           part any hair to examine the skin underneath. Don’t forget to examine
•	New skin lumps, spots, ulcers, scaly patches or moles that weren’t
                                                                           under your breasts and in the groin area.
   there before
•	Marks (including moles) on the skin that have changed shape,            Arms and hands
   colour, texture or size
                                                                           Examine each arm in turn beginning with the hands. Look at both the
• Sores that do not heal                                                   front and back of your hands and check between your fingers (the web
• Any areas on the skin that are itchy, painful or bleed                   spaces) and your fingernails. Examine all around your upper and lower
                                                                           arms (remember to use a mirror for places you can’t see) and raise
                                                                           your arms above your head to check each armpit.
How to examine your skin
Ideally you should examine your skin in a warm, well-lit room with the     Back
following equipment:
                                                                           If you have someone who can look at your back for you that is the
• A chair                                                                  easiest method of examination. If you want to do it yourself, use a
• A full-length mirror                                                     full‑length mirror in conjunction with a hand-held mirror. Look at the
                                                                           whole of your back starting at the top. Examine both shoulders to the
• A hand-held mirror                                                       middle of your back. Working from each side to the middle, traversing
• A comb                                                                   your back as you go, move down past your hips to your bottom.

30                                                                                                                                              31
Legs and feet                                                                Example: Red bleeding lump, 16/5/20
Sit down to examine the front and sides of your upper and lower legs.
Remember to look at your groin area including the genitals. Look at
your feet, paying particular attention to the soles and between your
toes. Remember to check your toenails.

Recording what you find
You might find it helpful to keep a photographic record of any skin
marks that you notice to see if they get any bigger, or change
in any way.
You can also record any skin changes that you are worried about on
these diagrams of the front and back of the body. As shown in the
example here, draw a small circle on the diagram in the approximate
position you found the skin problem. Write down the date that you
noticed it, and any other remarks such as ‘bleeding’ or ‘itchy’. This will
help remind you and assist the dermatologist when they see you at
your next visit.
If you notice any new lump, bump, ulcer, sore, scaly patch or
changing mole that lasts for longer than 2–3 weeks, contact
your dermatologist for advice.

32                                                                                                                 33
Sun protection                                                              UV UV             UV UV UV UV UV                               UV UV UV UV

                                                                            1 2 3 4 5 6 7 8 9 1011
                                                                                                                                                                      +
                                                                             INDEX    INDEX   INDEX   INDEX      INDEX     INDEX   INDEX   INDEX   INDEX   INDEX   INDEX
It is important to protect your skin from excessive sun exposure.
This includes when you are undertaking outdoor activities such as
gardening, walking and sports.
                                                                            NO PROTECTION                     PROTECTION                             EXTRA
The three golden rules are:                                                   REQUIRED                         REQUIRED                            PROTECTION

                                                                               You can         Seek shade during midday hours              Avoid being outside during
1. Prevent yourself from burning in the sun                                   safely stay                                                         midday hours
                                                                                              Slip on a shirt, slop on sunscreen and
                                                                               outside
2. Avoid sunbathing                                                                                        slap on a hat                   Make sure you seek shade
                                                                                                                                            Shirt, sunscreen and hat
3. Do not use artificial tanning beds                                                                                                               are a must

From April to October you should cover your body as much as                World Health Organisation (WHO) UV index
possible by using a hat, long-sleeved clothing and sunglasses.
Use a good quality sunscreen with at least SPF 30 and a 4-star rating
(this information can be found on the product) and stay in the shade.
Note that between 11am–3pm the sun is particularly intense.
                                                                           Vitamin D
The UV index
                                                                           People who need to take extra precautions to reduce sun exposure
You can find out how damaging the sun is at different times of day and     may become deficient in vitamin D which is important for the healthy
in different parts of the world by using the ultraviolet (UV) index. The   function of the body.
index is widely available in weather reports, online, and you can also
download an app and receive alerts.                                        At least 90% of the vitamin D that the body needs is produced in the
                                                                           skin after sun exposure; vitamin D is quite hard to obtain through diet
The higher the UV index number, the higher the risk of skin and eye        alone. Only a few foods are rich in vitamin D including oily or fatty fish
damage. Although people with a darker skin are more protected, a           such as salmon, sardines, tuna, mackerel and also cod liver oil.
UV index of 7/8 or above puts them at risk of sun damage. Very light
skinned people are at risk with a UV index as low as 3.                    Certain foods can be fortified with vitamin D including some types of
                                                                           cow’s milk, soy milk, orange juice, cereals and oatmeal.
                                                                           If you think that you may be at risk of vitamin D deficiency because
                                                                           you are being careful about sun protection talk to your GP or
                                                                           transplant doctor. If a blood test shows that your vitamin D level is low
                                                                           it is easy to treat with vitamin D tablets.

34                                                                                                                                                                         35
Further information                             Dermatology Department
                                                The Royal London Hospital
British Association of Dermatologists (BAD)
Information about skin care for                 Contact numbers
pre-transplant and transplant patients.
www.bad.org.uk                                                        Michelle Marshall
                                                 Dermatology          michellemarshall1@nhs.net
British Society for Skin Care in
Immunosuppressed Individuals (BSSCII)            skin cancer CNS      020 3594 2102
This organisation, linked to the BAD,                                 07934 904089
was founded in 2011.
www.bsscii.org.uk

International Transplant
Skin Cancer Collaborative (ITSCC)
Information on skin care and
transplant medication.
www.itscc.org

Cancer Research UK
Information about cancer and cancer care.
General enquiries 0300 123 1022
www.cancerresearchuk.org

Macmillan Cancer Support
Cancer information and support charity.
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Skin Care in Organ Transplant Patients Europe
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36                                                                                                37
Patient diary
Please use this diary to keep a record of your clinic visits

                                                               Comments                                          Next appointment
     Visit       Outcome
                                                               Write down anything you want to mention at your
     date        (treatment etc)                                                                                  Date     Time
                                                               next visit

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38                                                                                                                                39
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এই তথ��েলা সহেজ পড়া যায় অথবা ব�হৎ ি�ে�র মত িবক� ফরম�ােট পাওয়া যােব, এবং
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    অনুেেরােধ
          রােধ অন�  অন� ভাষায়ও  ভাষায়ও পাওয়া     পাওয়া �যেত  �যেত পাের।পাের। আেরা    আেরা তেথ�র    তেথ�র জন�  জন� আপনার  আপনার ি�িনক�াল ি�িনক�াল �েমর                 �েমর
সােথঅনুকথা
         েরােধ       ন। ভাষায়ও পাওয়া �যেত পাের। আেরা তেথ�র জন� আপনার ি�িনক�াল �েমর
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    সােথ
    সােথ কথা বলুন।
Na żądanie te informacje mogą zostać udostępnione w innych formatach, takich
    Na żądanie              te     informacje mogą                      zostać             udostępnione                   w innych              formatach, takich
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    Na   żądanie
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Aby uzyskać więcej informacji, porozmawiaj ze swoim zespołem specjalistów.            do     czytania,          a  także          w   innych                językach.
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Macluumaadkaan                       waxaa      informacji,
                                                     loo heli karaa    porozmawiaj   qaab kale,        ze swoim
                                                                                                             sida ugu      zespołem
                                                                                                                                akhrintaspecjalistów.      ugu fudud,
    Macluumaadkaan waxaa
    Macluumaadkaan                          waxaa loo     loo heli heli karaa karaa qaab    qaab kale,   kale, sida
                                                                                                                  sida ugu   ugu akhrinta
                                                                                                                                      akhrinta ugu                  ugu fudud,
                                                                                                                                                                            fudud,
    Macluumaadkaan                          waxaa         loo      heli
ama far waa weyn, waxana laga yabaa in lagu heli luuqaado Kale, haddii        karaa         qaab         kale,    sida       ugu      akhrinta                      ugu
                                                                                                                                                                      la fudud,
    ama     far
    Macluumaadkaan
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                                                                                                                  sida       ugu        Kale,
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codsado.    farWixiiwaa        weyn,
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                                                                                             kala lagu
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                                                                                            in lagu heli    hadal         kooxda
                                                                                                                  luuqaado Kale,           xarunta          haddii la
    codsado. Wixii
caafimaadka.         Wixii macluumaad
                                    macluumaad dheeraad           dheeraad ah, kala                 kala hadal
                                                                                                            hadal kooxda  kooxda xarunta   xarunta
    caafimaadka.
    codsado.
    caafimaadka.     Wixii macluumaad dheeraad ah, kala hadal kooxda xarunta
    caafimaadka.
Bucaafimaadka.
     bilgi, kolay okunurluk veya büyük baskılar gibi alternatif biçimlerde
    Bu
    Bu  bilgi, kolay               okunurluk             veya büyük                   baskılar            gibi  alternatif biçimlerde
    Bu bilgi,
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                    ve talep       okunurluk
                                         üzerine veya
                                   okunurluk             veya
                                                         Alternatif  büyük
                                                                     büyük            baskılar
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                                                                                 Dillerde                 gibi
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                                                                                                    sunulabilir.alternatif Dahabiçimlerde
                                                                                                                                     biçimlerde
                                                                                                                                       fazla bilgi için
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                                  talep        üzerine
                                               üzerine   veya   Alternatif
                                                                     büyük
                                                                Alternatif            Dillerde
                                                                                      baskılar
                                                                                      Dillerde            sunulabilir.
                                                                                                          gibi  alternatif
                                                                                                          sunulabilir.           Daha
                                                                                                                                 Dahabiçimlerde    fazla
                                                                                                                                                   fazla            bilgi için
    sunulabilir,          ve
klinik ekibinizle irtibata geçin. talep        üzerine          Alternatif            Dillerde            sunulabilir.           Daha              fazla bilgi      bilgi için
                                                                                                                                                                             için
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    klinik ekibinizle irtibata geçin.
    klinik ekibinizle irtibata geçin.
      ‫ﺳﺎﺟﯾﮐﺳہﺎ ﭘﮐڑہھﻧﭘڑﮯھﻧﻣﯾﮯںﻣآﯾﺳںﺎ آنﺳﯾﺎﺎنﺑ ﯾڑﺎا ﭘﺑڑراﻧ ﭘٹرﻧاوٹراور‬،‫ﮨﯾﺟںﯾ‬،‫سﯾﭨﻣﯾسںﻣدﯾﺳںﺗﯾدﺎﺳبﺗﯾﺎﮐبﯽ ﮐﺟﺎﯽ ﺳﺟﺎﮑﺗﺳﯽﮑﮨﺗﯾﯽں‬              ‫ﯾہ ﻣﻌﻠوﻣﺎت ﻣﺗﺑﺎدل ﻓﺎرﻣ‬
           ‫ٹ ااوورر‬‫ٹ‬  ‫ن ﯾﯾﺎﺎ ﺑﺑڑڑاا ﭘﭘررﻧﻧ‬
                                         ‫ن‬ ‫ﺳﺎﺎ‬
                                             ‫ﺳ‬ ‫ں آآ‬
                                                  ‫ں‬‫ﮯ ﻣﻣﯾﯾ‬
                                                        ‫ﮯ‬  ‫ﺳﺎﺎ ﮐﮐہہ ﭘﭘڑڑھھﻧﻧ‬  ‫ﺳ‬‫ﺟﯾﯾ‬
                                                                                 ‫ﺟ‬  ،،‫ں‬
                                                                                      ‫ں‬ ‫ﯽ ﮨﮨﯾﯾ‬
                                                                                             ‫ﯽ‬  ‫ﮑﺗﺗ‬
                                                                                                  ‫ﮑ‬  ‫ﺳ‬
                                                                                                     ‫ﺳ‬  ‫ﺟﺎﺎ‬
                                                                                                          ‫ﺟ‬ ‫ﯽ‬
                                                                                                            ‫ﯽ‬ ‫ب ﮐﮐ‬
                                                                                                                 ‫ب‬  ‫ﺳﺗﺗﯾﯾﺎﺎ‬
                                                                                                                          ‫ﺳ‬‫ں دد‬
                                                                                                                              ‫ں‬ ‫س ﻣﻣﯾﯾ‬
                                                                                                                                     ‫س‬  ‫ل ﻓﻓﻓﺎﺎﺎرررﻣﻣﻣﯾﯾﯾﭨﭨﭨ‬
                                                                                                                                                           ‫ت ﻣﻣﺗﺗﺑﺎدل‬
                                                                                                                                                                    ‫تﺳﻣﺗ‬
                                                                                                                                                           ‫ﺖﺑﺑﺎﺎ ﭘددل‬
                                                                                                                                                                           ‫ﯾﯾہہ ﻣﻣﻌﻌﻠﻠوﻣﺎ‬
                                                                                                                                                                       ‫رووﺧﻣﻣﺎﺎﻮات‬
                                                                                                                                                                                 ‫ﯾہ ﻣدﻌﻠ‬
     ‫ﯽﭘﻨﯽ‬
        ‫ر ا‬،‫ﮯﭘﻨ‬   ‫ﯿ‬‫ﻟ‬
              ‫ا او‬،‫ﮯ‬ ‫ﮯ‬
                   ‫ﮯ ﭘﻟرﯿﻧٹ‬‫ﮐ‬    ‫ت‬   ‫ﺎ‬  ‫ﻣ‬ ‫ﻮ‬‫ﻠ‬  ‫ﻌ‬ ‫ﻣ‬  ‫ﺪ‬
                              ‫ﮯ ﻣﯾﻌںﻠ آﻮﺳﻣﺎنتﯾﺎﮐﺑڑا‬  ‫ﯾ‬‫ﺰ‬ ‫ﻣ‬   ‫۔‬ ‫ﮟ‬  ‫ﯿ‬‫ﮨ‬  ‫ﯽ‬  ‫ﺘ‬ ‫ﮑ‬    ‫ﺳ‬   ‫ﻮ‬  ‫ﮨ‬
                                                        ‫ﮑﺟﺘﯾﯽﺳﺎ ﮨﯿﮐہﮟ۔ﭘڑﻣھﻧﺰﯾﺪ‬،‫بﯽﮨ ﮨﻮﯾںﺳ‬ ‫ب‬    ‫ﺎ‬‫ﯿ‬  ‫ﺘ‬
                                                                                                 ‫ﺳﮑﺗ‬‫ﺳ‬ ‫د‬   ‫ﯽ‬ ‫ﮭ‬‫ﺑ‬  ‫ﮟ‬ ‫ﯿ‬ ‫ﻣ‬     ‫ں‬ ‫ﻮ‬ ‫ﻧ‬‫ﺎ‬ ‫ﺑ‬ ‫ز‬
                                                                                                     ‫سﻧﻣﻮﯾںں دﻣﯿﺳﺗﯾﮟﺎ ﺑبﮭ ﮐﯽﯽدﺟﺳﺎﺘﯿﺎ‬  ‫ل‬   ‫د‬   ‫ﺎ‬  ‫ﺒ‬ ‫ﺘ‬ ‫ﻣ‬     ‫ﺮ‬
                                                                                                                                     ‫ت ﭘﻣﺗﺮﺑﺎدﻣﺘلﺒﺎﻓﺎدرلﻣﯾﭨزﺑﺎ‬         ‫ﺧﻌﻮﻠاوﺳﻣﺎﺖ‬   ‫رﻣ‬‫دﯾہ‬
             ‫ﯽ‬
             ‫ﻨﯽ‬
              ‫ ااﭘﭘﻨ‬،،‫ﮯ‬
                      ‫ﮯ ﻟﻟﯿﯿﮯ‬
                            ‫ت ﮐﮐﮯ‬
                                ‫ﮟ۔۔ ﻣﻣﺰﺰﯾﯾﺪﺪ ﻣﻣﻌﻌﻠﻠﻮﻮﻣﻣﺎﺎت‬
                                                         ‫ﯽ ﮨﮨﯿﯿﮟ‬
                                                               ‫ﮑﺘﺘﯽ‬
                                                                  ‫ﺳﮑ‬‫ب ﮨﮨﻮﻮ ﺳ‬
                                                                           ‫ﺳﺘﺘﯿﯿﺎﺎب‬
                                                                                  ‫ﯽ ددﺳ‬
                                                                                      ‫ﮟ ﺑﺑﮭﮭﯽ‬
                                                                                            ‫ں ﻣﻣﯿﯿﮟ‬
                                                                                                  ‫تﺑﺑﺎﺎﻧﻧﮐﻮﻮں‬
                                                                                                            ‫ل زز‬   ‫ﺖ ﭘﭘﺮﺮ ﻣﻣﺘﺘﺒﺒﺎﺎد‬   ‫ﺳ‬
                                                                                                                                      ‫ﺧﮐﻠﻮﻮﯿاا ﻨﺳ‬
                                                                                                                                                ‫ددررﺧ‬
             ‫ اﭘﻨﯽ‬،‫ﮟﻮ''ﺮ۔۔ﯾںﮟ'ﻣ۔ﯿﮟ ﺑﮭﯽ دﺳﺘﯿﺎب ﮨﻮ ﺳﮑﺘﯽ ﮨﯿﮟ۔ ﻣﺰﯾﺪ ﻣﻌﻠﻮﻣﺎت ﮐﮯ ﻟﯿﮯ‬                         ‫ﻧ‬ ‫ﺎ‬
                                                                                                         ‫ﯾ‬ ‫ﺑ‬
                                                                                                           ‫ﺮ‬ ‫ز‬‫ﮐ‬‫لﺎ‬
                                                                                                                ‫ﮯددتﺑ‬
                                                                                                                ‫ل‬    ‫ﺎ‬ ‫ﺒ‬
                                                                                                                       ‫ﺑ‬ ‫ﺘ‬‫ﺖ ﭨﭘﯿﺳﻢﺮﮯﻣﺳ‬
                                                                                                                                    ‫ﮑﯿﻞ‬
                                                                                                                                    ‫ﺖ‬
                                                                                                                                    ‫ﻢ‬ ‫ﺳ‬
                                                                                                                                      ‫ﭨ‬ ‫ﻞ‬ ‫ا‬  ‫ﻮ‬‫ﮑ‬ ‫دﮐﻠرﯿ ﻨﺧ‬
                                                                                                   ‫ﮟ'۔‬
                                                                                                     ‫ت ﮐﮐﺮﺮﯾﯾﮟ‬   ‫ﮯ ﺑﺑﺎﺎت‬    ‫ﺳﮯ‬ ‫ﻞ ﭨﭨﯿﯿﻢﻢ ﺳ‬
                                                                                                                                        ‫ﮑﻞ‬    ‫ﮐﮐﻠﻠﯿﯿ ﻨﻨﮑ‬
                                                                                                   ‫ﮐﻠﯿ ﻨﮑﻞ ﭨﯿﻢ ﺳﮯ ﺑﺎت ﮐﺮﯾﮟ'۔‬
Tell usus
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                     and   Liaison
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      services:   us if you need general information or advice about
                www.bartshealth.nhs.uk/pals
  Trust
  Please
  Trust services:
          contact www.bartshealth.nhs.uk/pals
                  us if you need general information or advice about
  about services:
  Trust Trust     www.bartshealth.nhs.uk/pals
              services.
        services:            www.bartshealth.nhs.uk/pals
                  www.bartshealth.nhs.uk/pals
  Trust services: www.bartshealth.nhs.uk/pals
Reference: BH/PIN/XXX
    Reference:    BH/PIN/XXX
    Reference: BH/PIN/XXX                           Publication date: December 2014
Publication
    Reference:date:
                  BH/PIN/XXX
All
    ©Barts
    Publication
    Reference:
    Publication
    our
               Health
         patient
                  date:
                  date:   NHS
                  BH/PIN/XXX
                 information
                                 Trustare reviewed every
                              leaflets              Updated:   July
                                                           three    2020
                                                                 years.
©Barts   Health
    Publication
    All our      NHS
                  date:
            patient     Trust
                     information leaflets are reviewed  every three years.
    Switchboard:
    ©Barts
    All our
    ©Barts
    All our
Switchboard:
            Health
            patient
    Publication
            Health
            patient
                     NHS
                     NHS
                 020NHS   020
                       3416
                           Trust
                     information
                  date:    Trust
                     information3416
                             5000      5000
                                 leaflets
                                 leaflets are
                                          are reviewed  every
                                                    Reference:
                                              reviewed  every three years.
                                                                 BH/PIN/132
                                                              three years.
    ©Barts  Health
    Switchboard:     020   Trust
                          3416  5000
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    ©Barts  Health   information
                     020
                     NHS
www.bartshealth.nhs.uk    3416
                           Trust leaflets
                                5000      are reviewed
                                                    All every
                                                        our   three
                                                            patient years.
                                                                    information leaflets
    www.bartshealth.nhs.uk
    Switchboard:     020 3416 5000
    www.bartshealth.nhs.uk
    www.bartshealth.nhs.uk
    Switchboard:     020
    www.bartshealth.nhs.uk3416  5000                are  reviewed  every three years
    www.bartshealth.nhs.uk
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