PROGRAM BOOK MARCH 4-6, 20l8 - ANAHEIM, CA DISNE YL AND HOTEL - Rackcdn.com
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PROGRAM BOOK MARCH 4–6, 20l8 ANAHEIM, CA DISNE YL AND ® HOTEL WIRELESS INTERNET ACCESS IS AVAILABLE. SSID: DLR Convention Wifi Connect to AT&T (log-in required every 24 hours)
APS Leadership and Staff 2017–2018 Board of Directors PRESIDENT TREASURER David A. Williams, PhD Jennifer A. Haythornthwaite, PhD University of Michigan Johns Hopkins University Ann Arbor, MI Baltimore, MD PRESIDENT-ELECT SECRETARY William Maixner, PhD DDS Patrick M. Dougherty, PhD Duke University Medical Center UTMD Anderson Cancer Center Durham, NC Houston, TX DIRECTOR-AT- LARGE Mark S. Wallace, MD University of California, San Diego La Jolla, CA DIRECTORS Claudia M. Campbell, PhD Theodore J. Price, PhD Johns Hopkins University University of Texas at Dallas Baltimore, MD Dallas, TX Robert C. Coghill, PhD Barbara Rakel, PhD RN Cincinnati Children’s Hospital University of Iowa Cincinnati, OH Iowa City, IA Robert R. Edwards, PhD Barbara St. Marie, PhD ANP GNP Brigham and Women’s Hospital University of Iowa Chestnut Hill, MA Iowa City, IA Edward Michna, JD MD PharmD Gary Alan Walco, PhD ABP Brigham and Women’s Hospital Seattle Children’s Hospital Boston, MA Seattle, WA LIAISON TO IASP Michael S. Gold, PhD University of Pittsburgh Pittsburgh, PA STAFF Chief Executive Officer Susan Farrell Stock, MPS Chief Operations Officer Carly Reisner Education Manager Brianna Johnson Membership and Marketing Manager Caryn Giznik Membership and Marketing Coordinator Meghan McLaughlin Operations and Education Coordinator Emily Panci APS 2018 SCIENTIFIC SUMMIT 2 A M E R I C A N P A I N S O C I E T Y. O R G
Contents General Information APS Leadership. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Floor Plans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Day at a Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2018 Scientific Program Committee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Welcome from the APS President. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Continuing Education. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Recognition 2018 Young Investigators . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Featured Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 APS Honors Excellence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Special Events and Sponsorship Grantors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 International Association for the Study of Pain . . . . . . . . . . . . . . . . . . . . . . 21 Exhibits and Posters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Exhibits and Posters Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Exhibitors by Product Type. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Exhibitor Listing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Lotus Clinical Research. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Full Schedule Sunday, March 4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 Monday, March 5. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 Tuesday, March 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 GET THE MOST OUT OF THE MEETING WITH THE SUMMIT APP. Floor plans, handouts, and detailed session descriptions can be accessed from your smar tphone or tablet. Download the app at tripbuildermedia.com/apps/aps2018 or search for APS 2018 Scientific Summit in your app store. APS 2018 SCIENTIFIC SUMMIT 3 A M E R I C A N P A I N S O C I E T Y. O R G
FLOOR MAP FANTASY TOWER Banquet Kitchen West Freight Elevator 3 2 Stairs And Escalator To Roof Parking Magic Kingdom UPPER LEVEL Ballroom West Foyer Magic Kingdom Magic Kingdom Ballroom Terrace Corridor Ballroom Business Center REST ROOMS CONVENTION CENTER 4 1 B Ticket East Stairs To Lobby Level Magic Kingdom Ballroom East Foyer A Ticket Elevator To Lobby Level Stairs To Magic Kingdom Ballroom LOBBY LEVEL Sleeping Beauty Pavilion Service Corridor Serving Area Downstairs Dressing Room STAGE E J 1,200 Alternate Meeting Rooms SQ. FT. LOWER LEVEL D I Disneyland® Disneyland® Disneyland® South Center North Ballroom Ballroom Ballroom Disneyland® Exhibit Hall Monorail A B B A C H C B A Disneyland® Grand Ballroom B G Disneyland® South Exhibit Hall Disneyland® North Exhibit Hall Disneyland® Disneyland® Disneyland® South North Center Disneyland® South Exhibit Hall Corridor A F Lounge Lounge Lounge Disneyland® Exhibit Hall Foyer C B A Disneyland® Grand Ballroom Registration Area REST ROOMS Castle ENTRANCE ELEVATORS NORTH LOBBY ADVENTURE TOWER Explorer Adventure Outpost Nile Congo ELEVATORS ELEVATORS SOUTH LOBBY NORTH LOBBY Safari Tiki Amazon Zambezi Oasis FRONTIER TOWER REST ROOMS Wilderness Pioneer Columbia Mississippi Western Frontier Mark Twain Board Room Mark Twain Terrace ©Disney APS 2018 SCIENTIFIC SUMMIT 4 A M E R I C A N P A I N S O C I E T Y. O R G
DISNEYLAND ® HOTEL MAP VICES Fantasy Parking Lot CONVENT (Self-Parking) Conven Disneyland® Exhibit Hall Low Disneyland® Grand Ballroom Downtown Disney® District and Theme Parks Ma wn Coffee Goofy’s House Steakhouse 55 Kitchen Up ON Upper Level: Magic Kingdom® Ballroom op Sleeping Beauty Pavilion HOTEL FEATURES & SERVICES Sundries Front Desk es Guest HOTEL Services FEATURES & SERVICES Fantasy Parking Lot Advent (Self-Parking) 1 Front Desk Bell & Valet Services 2 Guest Services Disneyland® Exhibit Hall Nil Co TO Rose COME &Court Garden Disneyland® Grand Ballroom 3 Bell Valet Services 4 Rose Court Garden Za ES Adventure 5 Adventure LawnLawn Am nge 6 Frontier Lawn Oa Frontier Lawn 7 Magic Kingdom Lawn Magic Kingdom® ® Frontie Lawn Magic Kingdom Lawn 8 Fitness Center Coffee We 9 Guest Laundry House Goofy 10 About Business Center Health Club Steakhouse Goofy’s Rose Court 55 Kitchen Garden Wi Pio Business SHOPPING Center & RECREATION Upper Level: Frontier Magic Kingdom® Ballroom Co Lawn 11 Disney’s Fantasia Shop Sleeping Beauty Pavilion HOTEL FEATUR 12 small world Gifts & Sundries Outdoo Front Desk 13 Monorail Pool & Slides Adventure Ro 14 D Ticket Pool Dreams Lawn Guest Servic Ad Lawn 15 E Ticket Pool Bell & Valet Fro 16 Outdoor Fireplace Rose CourtMa G RESTAURANTS & LOUNGES Adventure La 17 Steakhouse 55 & Lounge GUEST RO Frontier Law Areas 18 Goofy’s Kitchen Magic Kingdom® Fantasy Disneyland Disneyland® Resort ResortCenter Center 19 Tangaroa Terrace Lawn MagicAdvent Kingd Frontier Parking Lot ©Disney 20 Trader Sam’s Map Not To Scale Information Subject To Change Without Notice GoofyFrontie About 21 The Coffee House (AddCen Business fi Frontier LEGEND Lawn Elevators Restrooms Telephones ATM Monorail Station Bus Pick-Up Designated Smoking Areas Disneyland ® Resort Disneyland ResortCenter Center Frontier Pa Automated External Defibrillator ©Disney Map Not To Scale Information Subject To Change Without Notice APS 2018 SCIENTIFIC SUMMIT 5 A M E R I C A N P A I N S O C I E T Y. O R G
Day at a Glance SUNDAY, MARCH 4 8 am–Noon A Patient-Oriented Approach to Navigating the Magic Kingdom Transition from Acute to Chronic Pain: A Fundamental Ballroom 2 Course 8 am–Noon Six Building Blocks Workshop: Implementing Team- Castle Based Management of Chronic Opioid Therapy 8 am–4:30 pm APS Conference on Analgesic Trials Magic Kingdom Ballroom 1 and 4 1–4:15 pm Early Career Forum South Ballroom 4:30–6 pm Early Career Professional/Mentor Reception Sleeping Beauty Pavilion 6–7:30 pm Clinical and Basic Science Data Blitz Magic Kingdom Ballroom 2 7:30–9 pm Basic Science Dinner Magic Kingdom Scientific Communication: Thinking Outside of the Peer Ballroom 1 and 4 Review Box MONDAY, MARCH 5 6–7 am Yoga Sleeping Beauty APS requests that participants make a donation to the Pain Research Pavilion Fund. 7–7:30 am Posters and Breakfast Experience Exchange 7:30–8 am Gathering and Welcome Center Ballroom 8–8:30 am Plenary Lecture Center Ballroom The Biology of Infant and Childhood Pain: It All Begins Here 8:30–9 am Plenary Lecture Center Ballroom Variability in the Pain Experience After Injury APS 2018 SCIENTIFIC SUMMIT 6 A M E R I C A N P A I N S O C I E T Y. O R G
Day at a Glance MONDAY, MARCH 5 9:15–10:45 am Concurrent Symposia Magic Kingdom Putting the Spotlight on Social: An Innovative Ballroom 1 and 4 Multidisciplinary, Multispecies Approach for Examining the Influence of Social Context in Pain Magic Kingdom Migraine and Sleep Deficiency in Adolescents: Ballroom 2 Understanding Shared Mechanisms from Bench to Bedside Center Ballroom Psychological Treatments for Chronic Pain: Who Benefits and Why? South Ballroom Exploiting Cellular and Molecular Mechanisms of Neuroinflammation for New Treatments of Chronic Pain 10:45–11 am Refreshment Break Center Lounge and Magic Kingdom Foyer 11 am–Noon Shared Interest Group Meetings Center Ballroom Measurement of Pain and Its Impact/Geriatric Pain/ Nursing South Ballroom Pain and Disparities Magic Kingdom Pain in Sickle Cell Disease Business Meeting Ballroom 1 and 4 Magic Kingdom Headache Business Meeting Ballroom 2 Monorail Genetics and Pain Business Meeting 11 am–Noon Essential Legal Concepts to Avoiding Lawsuits, Castle Reducing Taxes and Protecting Your License 12:15–1:15 pm Lunch; Exhibits; Education; and Author-Attended, Experience Exchange Odd-Numbered Posters 12:15–12:35 pm The (Mis)Socialization of Children’s Pain Memories Solutions Theater 12:55–1:15 pm Hazardous Alcohol and Opioid Use in Chronic Pain: An Solutions Theater Assessment of Frequency and Impact 1:30–2 pm Plenary Lecture Center Ballroom Spinal Mechanisms of Spinal Cord Injury–Induced Neuropathic Pain: Implications for Novel Therapeutic Targets 2–2:30 pm Plenary Lecture Center Ballroom Assessment and Management of Neuropathic Pain: Advances, Challenges, and Opportunities APS 2018 SCIENTIFIC SUMMIT 7 A M E R I C A N P A I N S O C I E T Y. O R G
Day at a Glance MONDAY, MARCH 5 2:30–2:45 pm Refreshment Break Center Lounge 2:45–4:15 pm Concurrent Symposia Magic Kingdom Novel Mechanisms Underlying Risk for Acute and Chronic Ballroom 1 and 4 Postsurgical Pain: Role of Peripheral Pain Processing, Central Sensitization, and Genomics Center Ballroom Muscle Pain Mechanisms: It’s Time to Dive Deep South Ballroom Mechanism-Based Approach to Clinical Trial Design in Chemotherapy-Induced Peripheral Neuropathy Magic Kingdom At the Intersection of Affect Regulation, Reward/Value Ballroom 2 Processes, and Placebo: Altered Human Psychological, Neurobiological, and Opioiderigic Systems in Chronic Pain 4:30–4:50 pm Sex Differences in Pain and Analgesia Solutions Theater 4:30–5:30 pm Networking and Collaboration Sessions Center Ballroom Developmental Mechanisms and Special Populations Magic Kingdom Central, Peripheral, and Psychosocial Pain Mechanisms Ballroom 2 South Ballroom Neuropathic Pain, Exercise, and Cannabinoids 4:30–5:30 pm NIH Session Monorail Clinical Trials Panel Discussion 4:30–5:30 pm Networking, Education, and Exhibits Experience Exchange 5:10–5:30 pm Sensory Neuron–Restricted CB1R Does Solutions Theater Not Mediate Analgesia 5:45–7:45 pm Awards Reception Magic Kingdom Cosponsored by the Rita Allen Foundation Ballroom 1 and 4 TUESDAY, MARCH 6 6–7 am Yoga Sleeping Beauty APS requests that participants make a donation to the Pain Research Pavilion Fund. 7–7:30 am Posters and Breakfast Experience Exchange 7:30–8:30 am NIH Session Castle Tips for the Mid-Career Investigator Panel Discussion APS 2018 SCIENTIFIC SUMMIT 8 A M E R I C A N P A I N S O C I E T Y. O R G
Day at a Glance TUESDAY, MARCH 6 7:30–8:30 am Shared Interest Group Meetings Center Ballroom Psychosocial Research South Ballroom Clinical Trials Business Meeting Magic Kingdom Pain Education Business Meeting Ballroom 1 and 4 Magic Kingdom Primary Care Ballroom 2 Monorail Basic Science Business Meeting 8:45–9:15 am Plenary Lecture Center Ballroom Taking Aim Is Easier When You Know the Target: Moving Toward Mechanism-Based Pain Assessment 9:15–9:45 am Plenary Lecture Center Ballroom In Pursuit of More Powerful Nonpharmacologic Treatments for Musculoskeletal Pain with Centralized Features 9:45–10 am Refreshment Break Experience Exchange 10–11:30 am Networking and Education Experience Exchange 10–11 am Women in Leadership Solutions Theater 10:15–10:45 am Meet APS's Shared Interest Group Chairs Experience Exchange Military/Veterans, Primary Care, Pain in Sickle Cell Disease 10:30–11:30 am Meet the Editor of The Journal of Pain Booth 102 11–11:30 am Meet APS's Shared Interest Group Chairs Experience Exchange Basic Science, Ethics, Headache, Nursing, Pain and Genetics, Psychosocial Research, Sex and Gender in Pain and Analgesia 11–11:30 am Meet the Early Career Advisory Group Early Career Lounge 11:10–11:30 am Conducting Clinical Trials in Solutions Theater Osteoarthritis of the Knee 11:30 am–12:30 pm Lunch; Exhibits; Networking; and Author-Attended, Experience Exchange Even-Numbered Posters APS 2018 SCIENTIFIC SUMMIT 9 A M E R I C A N P A I N S O C I E T Y. O R G
Day at a Glance TUESDAY, MARCH 6 12:45–1:45 pm Shared Interest Group Meetings Magic Kingdom Pain in Infants, Children, and Adolescents Ballroom 1 and 4 South Ballroom Military/Veterans Center Ballroom Ethics/Pain Rehabilitation Magic Kingdom Sex and Gender in Pain and Analgesia Business Meeting Ballroom 2 Monorail Complementary and Alternative Medicine Business Meeting 2–2:30 pm Wilbert E. Fordyce Award Lecture Center Ballroom Simplifying Evidence-Based Pain Self-Management Therapies for Chronic Pain: Rationale, Efficacy, and Implementation 2:30–3 pm Frederick W.L. Kerr Award Lecture Center Ballroom Distributed Processing of Pain: From the Spinal Cord to the Brain 3–3:15 pm Refreshment Break Center Lounge 3:15–4:45 pm Concurrent Symposia Magic Kingdom Neurobiological Mechanisms Supporting Integrative Ballroom 1 and 4 and Mind-Body Therapies for Pain South Ballroom Descending Modulation of Pain and the Endocannabinoid System: Sites, Mechanisms, and Therapeutic Potential Magic Kingdom Novel Directions in Basic Research: Rita Allen Scholars Ballroom 2 Center Ballroom Bottom-Up vs Top-Down: The Search for Effective Mechanisms in Psychosocial Treatments for Chronic Pain APS 2018 SCIENTIFIC SUMMIT 10 A M E R I C A N P A I N S O C I E T Y. O R G
S AV E T HE DAT E MILWAUK EE , W I | A PRIL 3−6, 2019 a m e r i c a n p a i n s o c i e t y. o r g /2 0 1 9 AMERICAN PAIN SOCIE T Y SCIEN T IFIC MEE T ING
2018 scientific program committee CHAIR Tonya M. Palermo, PhD Professor Seattle Children’s Research Institute CHAIR-ELECT Luda Diatchenko, MD PhD Professor McGill University COMMITTEE MEMBERS Geoffrey Bove, PhD DC Associate Professor University of New England Robert Coghill, PhD Professor Cincinnati Children’s Hospital Anna Kratz, PhD Assistant Professor University of Michigan Rosemary Polomano, PhD RN FAAN Professor University of Pennsylvania Linda L. Porter, PhD Health Science Policy Advisor for Pain National Institute of Neurological Disorders and Stroke/National Institutes of Health Jennifer Rabbitts, MD Assistant Professor Seattle Children’s Research Institute Kristin Schreiber, MD PhD Anesthesiologist Brigham and Women’s Hospital Scott Strassels, PhD PharmD Pharmacist Optum Hospice Pharmacy Services Ajay Wasan, MD MSc Professor University of Pittsburgh EX- OFFICIO David A. Williams, PhD APS President University of Michigan APS 2018 SCIENTIFIC SUMMIT 12 A M E R I C A N P A I N S O C I E T Y. O R G
Welcome from the APS President Dear Colleagues, Welcome to Anaheim! On behalf of the American Pain Society Board of Directors, the Scientific Program Committee, and staff, thank you for joining us for the APS Scientific Summit. As a society, we look forward to this opportunity to gather scientists, clinicians, and policy advocates all working together to reduce pain-related suffering in the United States and worldwide. As the landscape of the pain field shifts, so must our approach to meeting the needs of pain science and management community. The 2018 Scientific Program Committee, chaired by Dr. Tonya Palermo, has created a program that allows us to dig deeper into Understanding the Mechanisms of Pain. With six plenary sessions, 12 symposia, and nearly 300 poster presentations, the content caters to a multidisciplinary audience across basic, translational and clinical research. Along with this excellent educational programming comes the Solutions Theater and Experience Exchange, formal and informal networking opportunities, voting for the best posters, an early career forum for our future leaders in pain research and treatment, and the presentation of our prestigious awards. Thank you for selecting me to serve as your President for the past two years. It has been an honor. As I pass the baton to Dr. Bill Maixner, I know the Society is in good hands. Thank you again for attending this meeting, and please let us know if there is anything we can do to make your experience more beneficial. With kind regards, David A. Williams, PhD APS President APS 2018 SCIENTIFIC SUMMIT 13 A M E R I C A N P A I N S O C I E T Y. O R G
Continuing Education This meeting offers continuing education (CE) credits for physicians, psychologists, pharmacists, nurses, and dentists. Credit will be awarded for sessions attended and evaluated. Successful completion requires that participants register for the meeting, attend and participate, and complete an online evaluation. Participants will receive their CE/CME certificates immediately after they submit their evaluations online. PHYSICIANS DENTISTS The American Pain Society (APS) is The American Pain Society has applied to accredited by the Accreditation Council for Affordable CE Credits as a cosponsor for Continuing Medical Education (ACCME) to CE for dentists at the Scientific Summit. provide continuing medical education for Affordable CE Credits is a recognized ADA physicians. APS designates this live activity CERP provider. ADA CERP is a service of for a maximum of 15.50 AMA PRA Category the American Dental Association to assist 1 Credit(s)™. Physicians should claim only dental professionals in identifying quality the credit commensurate with the extent of providers of continuing dental education. their participation in the activity. APS has requested designation for a maximum of 15.50 contact hours. PSYCHOLOGISTS The American Pain Society has applied Disclosure to Amedco as a cosponsor for CE for APS requires that planners and presenters psychologists at the Scientific Summit. disclose the existence of any relevant Amedco is approved by the American financial or other relationship they and/ Psychological Association (APA) to sponsor or their spouse/partner have with the CE for psychologists. APS has requested manufacturers of any commercial interest designation for a maximum of 15.50 hours (defined as any entity producing, marketing, of CE credit for psychologists for sessions reselling, or distributing healthcare goods attended and evaluated. or services consumed by, or used on, patients) whose products or services relate PHARMACISTS to the topics presented. APS also requires The American Pain Society has applied disclosure of the intent to discuss unlabeled to Amedco as a cosponsor for CE for or investigational use(s) of a commercial pharmacists at the Scientific Summit. product. The Scientific Program Committee Amedco is approved by the Accreditation reviews potential conflicts of interest as Council for Pharmacy Education (ACPE) submitted by planners and presenters and to sponsor CE for pharmacists. APS has resolves such conflicts so as to ensure the requested designation for a maximum of content of the activity is aligned with the 15.50 hours of CE credit for pharmacists for interests of the public. Detailed disclosure sessions attended and evaluated. information will be published in course NURSES materials. Learners also will be informed The American Pain Society has applied to when no relevant financial relationships the American Association for Neuroscience exist. Nurses (AANN) as a cosponsor for CE for Disclaimer nurses at the Scientific Summit. AANN The material presented in this activity is an accredited provider of continuing represents the opinion of the speakers and nursing education by the American not necessarily the views of APS. Nurses Credentialing Center's (ANCC's) Commission on Accreditation. APS has Statement of Non-Endorsement requested designation for a maximum of Accredited status does not imply 15.50 contact hours. endorsement by APS, ACCME, APA, ADA CERP, ACPE, or ANCC of any commercial products displayed in conjunction with this activity. APS 2018 SCIENTIFIC SUMMIT 14 A M E R I C A N P A I N S O C I E T Y. O R G
2018 Young Investigators APS is pleased to grant Young Investigator Travel Awards to 60 trainees to attend this meeting. These individuals will present their research during designated poster sessions. Funding for the 2018 Young Investigator Travel Award Program is supported by the National Center for Complementary and Integrative Health (NCCIH), the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Neurological Disorders aand Stroke (NINDS), National Institute of Drug Abuse (NIDA), and National Cancer Institute (NCI). Rachel Aaron, PhD Shaness Grenald University of Washington Johns Hopkins Medicine Natalie Hellman Alix Aboussouan University of Tulsa Ali Alsouhibani, MS PT Matthew Herbert Marquette University University of Alabama at Birmingham Tyler Bell Lorraine Hoyos University of Alabama at Birmingham University of Florida Samantha Bento Behnaz Jarrahi University of Maryland Baltimore County Stanford University Giovanni Berardi Devin Johnson Marquette University Brigham & Women’s Hospital Brandon Boring Geoffroy Laumet, PhD Johns Hopkins Medicine MD Anderson Cancer Center Hailey Bulls, PhD Janelle Letzen Moffitt Cancer Center University of Florida Frank Buono Dustin Liebling Yale University Montefiore Medical Center Michael Burton, PhD Hans Linsenbardt, BS MA The University of Texas at Dallas Texas A&M University Bryan Copits Paige Lysne Washington University in St. Louis University of Florida Ashley Cowie Kathryn Madalena Medical College of Wisconsin Ohio State University Elizabeth Danielson, MA Misty Malamakal, PhD Indiana University Texas A&M University Catlin Dennis Stacy McAllister, PhD Oregon Health & Science University Stanford University Joanne Dudeney Jordan McCall Seattle Children’s Hospital Washington University in St. Louis Jose Grajales-Reyes Christina McDonnell Washington University School of Brigham & Women’s Hospital Medicine in St. Louis APS 2018 SCIENTIFIC SUMMIT 15 A M E R I C A N P A I N S O C I E T Y. O R G
2018 Young Investigators Lisa McIlvried, PhD Vijay Samineni, PhD Washington University in St. Louis Washington University in St. Louis Samantha Meints, MS Victor Schneider Indiana University-Purdue University Cincinnati Children’s Hospital Medical Center Indianapolis Navdeep Singh Aaron Mickle Washington University in St. Louis Kimberly Stephens Johns Hopkins University Francie Moehring Medical College of Wisconsin Andrea Stevens Duquesne University Namrata Nanavaty Texas A&M University John Sturgeon, PhD University of Washington Sarah Nelson Boston Children’s Hospital Cassandra Sturycz, MA University of Tulsa Andrea Newman The University of Alabama Chloe Taub University of Miami Melanie Noel, PhD University of Calgary Kathryn Thompson University of Alabama at Birmingham Michael Owens University of Alabama at Birmingham Tyler Toledo University of Tulsa Cristina Peterson University of Minnesota Benjamin Van Dyke, MA The University of Alabama Vy Phan Trinity College Kenneth Weber, DC PhD Stanford University Anna Polaski Duquesne University Xin Zhang Duke University Luis Queme, MD PhD Cincinnati Children’s Hospital Medical Center Fenan Rassu, MS Texas A&M University Katelyn Sadler Duquesne University FIND OUT HOW YOU CAN APPLY FOR A YOUNG INVESTIGATOR TRAVEL AWARD AT AMERICANPAINSOCIET Y.ORG. APS 2018 SCIENTIFIC SUMMIT 16 A M E R I C A N P A I N S O C I E T Y. O R G
Featured Speakers MONDAY, MARCH 5 8–8:30 am Plenary Lecture The Biology of Infant and Childhood Pain: It All Begins Here Maria Fitzgerald, FMedSci FRS; University College of London 8:30–9 am Plenary Lecture Variability in the Pain Experience After Injury James C. Eisenach, MD; Wake Forest School of Medicine 1:30–2 pm Plenary Lecture Spinal Mechanisms of Spinal Cord Injury–Induced Neuropathic Pain: Implications for Novel Therapeutic Targets Susan G. Dorsey, PhD RN FAAN; University of Maryland School of Nursing 2–2:30 pm Plenary Lecture Assessment and Management of Neuropathic Pain: Advances, Challenges, and Opportunities Srinivasa N. Raja, MD; Johns Hopkins University TUESDAY, MARCH 6 8:45–9:15 am Plenary Lecture Taking Aim Is Easier When You Know the Target: Moving Toward Mechanism-Based Pain Assessment Roger B. Fillingim, PhD; University of Florida 9:15–9:45 am Plenary Lecture In Pursuit of More Powerful Nonpharmacologic Treatments for Musculoskeletal Pain with Centralized Features Susmita Kashikar-Zuck, PhD; Cincinnati Children’s Hospital 2–2:30 pm Wilbert E. Fordyce Award Lecture Simplifying Evidence-Based Pain Self-Management Therapies for Chronic Pain: Rationale, Efficacy, and Implementation Beverly E. Thorn, PhD; University of Alabama 2:30–3 pm Frederick W.L. Kerr Award Lecture Distributed Processing of Pain: From the Spinal Cord to the Brain Robert C. Coghill, PhD; Cincinnati Children's Hospital APS 2018 SCIENTIFIC SUMMIT 17 A M E R I C A N P A I N S O C I E T Y. O R G
APS Honors Excellence APS 2018 ACHIEVEMENT AWARDS APS recognizes excellence in the field of pain management and research by presenting awards for career achievement, pain scholarship, education, public service, advocacy on behalf of children, outstanding service to the society, and early career achievements. Congratulations to the 2018 APS award recipients! JOHN AND EMMA BONICA PUBLIC SERVICE AWARD Lorimer Moseley, DSc PhD University of South Australia WILBERT E. FORDYCE CLINICAL INVESTIGATOR AWARD Beverly E. Thorn, PhD University of Alabama FREDERICK W. L. KERR BASIC SCIENCE RESEARCH AWARD Robert C. Coghill, PhD Cincinnati Children’s Hospital JEFFREY LAWSON AWARD FOR ADVOCACY IN CHILDREN’S PAIN RELIEF Ruth E. Grunau, PhD The University of British Columbia JOHN C. LIEBESKIND EARLY CAREER SCHOLAR AWARD Jessica S. Merlin, MD PhD University of Pittsburgh ELIZABETH NARCESSIAN AWARD FOR OUTSTANDING EDUCATIONAL ACHIEVEMENTS IN THE FIELD OF PAIN Rollin M. Gallagher, MD MPH University of Pennsylvania DISTINGUISHED SERVICE AWARD Christopher M. Herndon, PharmD CPE Southern Illinois University Edwardsville FOR MORE INFORMATION ON THE AWARD WINNERS, VISIT AMERICANPAINSOCIETY.ORG/AWARDS. APS 2018 SCIENTIFIC SUMMIT 18 A M E R I C A N P A I N S O C I E T Y. O R G
Special Events and Sponsorship THANK YOU APS WOULD LIKE TO THANK ITS EDUCATIONAL GRANTORS FOR THEIR SUPPORT OF THE APS SCIENTIFIC SUMMIT. BIOGEN MA, INC. LILLY USA PFIZER REGENERON PHARMACEUTICALS, INC. SUPERNUS PHARMACEUTICALS, INC. APS 2018 SCIENTIFIC SUMMIT 19 A M E R I C A N P A I N S O C I E T Y. O R G
sponsors THANK YOU APS WOULD LIKE TO THANK ITS EDUCATIONAL GRANTORS FOR THEIR SUPPORT OF A FUNDAMENTAL COURSE. DAIICHI SANKYO, INC. LILLY USA PFIZER APS 2018 SCIENTIFIC SUMMIT 20 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibits and Posters SCHEDULE Experience Exchange The APS Scientific Summit will showcase products and services specifically designed SUNDAY, MARCH 4 for interdisciplinary leaders in the study and 12:30–4:30 pm treatment of pain. By visiting the experience Exhibit Setup exchange, you will experience firsthand the technology, products, and services that can help 2:30–4:30 pm you manage your professional goals and strategic Poster Setup objectives and keep you and your organization at the forefront of your field. Exhibitors will feature products and information in MONDAY, MARCH 5 the following areas: 7–7:30 am • Pharmaceutical • Clinical Research Posters and Breakfast • Medical Device • Publishing 7 am–5:30 pm • Medical Equipment • Business Experience Exchange Open and Supplies Management 12:15–1:15 pm • Laboratory/ Services Lunch; Exhibits; Education; and Diagnostic Testing • Education • Software • Recruitment Author-Attended, Odd-Numbered • Clinical Trial • Alternative Delivery Posters Management Systems 4:30–5:30 pm • Technology • Wearables Networking, Education, and • Lab Instruments • Mobile Apps Exhibits POSTERS The Scientific Summit will feature two author- attended poster sessions. The selected posters TUESDAY, MARCH 6 represent the best innovations and research in the 7–7:30 am study and treatment of pain. Posters and Breakfast Poster abstracts selected for presentation at 7 am–12:30 pm the annual meeting are available online in a Experience Exchange Open searchable database to allow registrants to plan their poster viewing in advance of the 10–11:30 am meeting. To search and view the abstracts, visit Networking and Education http://americanpainsociety.org/meetings-and- 11:30 am–12:30 pm events/2018-scientific-summit/poster-abstracts. Lunch; Exhibits; Networking; and Poster abstracts selected for presentation at the Author-Attended, Even-Numbered meeting will be published in a supplemental issue Posters of The Journal of Pain, the official journal of APS. 1–4 pm All attendees will receive this supplemental issue. Exhibit and Poster Teardown VIRTUAL EXHIBIT HALL The final exhibitor list and floor plan are available on the meeting app. Download the app at tribuildermedia.com/apps/aps2018 or search for APS 2018 Scientific Summit in your app store. APS 2018 SCIENTIFIC SUMMIT 22 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibits and Posters FLOOR PLAN as of February 23, 2018 APS 2018 SCIENTIFIC SUMMIT 23 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibits and Posters Exhibitors by Product Type as of February 23, 2018 Clinical Research Cincinnati Children's Hospital . . . . . . . . . . . . Booth 203 Chesapeake Research Group . . . . . . . . . . . . Booth 217 Lotus Clinical Research . . . . . . . . . . . . . . . . Booth 404 Premier Research . . . . . . . . . . . . . . . . . . . . Booth 409 Education American Chronic Pain Association (ACPA) . . Booth 213 International Association for the Study of Pain (IASP) . . . . . . . . . . . . . . . . . . Booth 114 NCCIH/NIH . . . . . . . . . . . . . . . . . . . . . . . . . Booth 416 U.S. Pain Foundation . . . . . . . . . . . . . . . . . . Booth 308 Laboratory/Diagnostic Testing AXIS Toxicology & Clinical Lab Service . . . . . Booth 200 ExpertMRI . . . . . . . . . . . . . . . . . . . . . . . . . . Booth 215 LabCorp/MedTox . . . . . . . . . . . . . . . . . . . . . Booth 310 Medical Device Arbor Medical . . . . . . . . . . . . . . . . . . . . . . . Booth 402 Intent Solutions . . . . . . . . . . . . . . . . . . . . . . Booth 414 Harvard MedTech, LLC . . . . . . . . . . . . . . . . . Booth 507 Karuna Labs . . . . . . . . . . . . . . . . . . . . . . . . Booth 118 LightForce Therapy Lasers by LiteCure Medical . . . . . . . . . . . . . . . . . . . Booth 408 Medoc Advanced Medical Systems . . . . . . . . Booth 201 Thorp Institute . . . . . . . . . . . . . . . . . . . . . . . Booth 116 Pharmaceutical Amgen Inc. . . . . . . . . . . . . . . . . . . . . . . . . . Booth 503 Daiichi Sankyo, Inc. . . . . . . . . . . . . . . . . . . . Booth 303 Publishing Pain Medicine News . . . . . . . . . . . . . . . . . . . Booth 202 The Journal of Pain . . . . . . . . . . . . . . . . . . . . Booth 102 Wolters Kluwer . . . . . . . . . . . . . . . . . . . . . . Booth 112 Other Adapt Pharma Inc. . . . . . . . . . . . . . . . . . . . Booth 515 AnaBios . . . . . . . . . . . . . . . . . . . . . . . . . . . Booth 301 Celling Biosciences . . . . . . . . . . . . . . . . . . . Booth 509 Syneos Health . . . . . . . . . . . . . . . . . . . . . . . Booth 410 Technology Global Gadgets . . . . . . . . . . . . . . . . . . . . . . Booth 511 APS 2018 SCIENTIFIC SUMMIT 24 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibitor Listing BOOTH 515 BOOTH 402 Adapt Pharma Inc. Arbor Medical Bldg 4 Suite 201 3808 Plaza Drive Radnor, PA 19087 Ann Arbor, MI 48108 adaptpharma.com www.arbormedicalinnovations.com Adapt Pharma, makers of NARCAN® Nasal Spray, Arbor Medical Innovations (AMI) is a technology is an innovative small business focused on startup company out of the University of developing cutting-edge treatments for patients Michigan that specializes in automated with special medical conditions. quantitative sensory testing systems for use in both clinical and MRI environments. AMI also BOOTH 213 offers custom medical device prototyping and American Chronic Pain Association software development services for healthcare (ACPA) professionals who are interested in growing great ideas into tangible prototypes and beyond. Come 4150 Roble Way see us at booth 402 or visit our website at www. Rocklin, CA 95677 arbormedicalinnovations.com to learn more. theacpa.org Since 1980 the ACPA has offered peer support and coping skills to help people with pain begin BOOTH 200 AXIS Toxicology & Clinical Lab Service their journey from patient to person. The ACPA continues to offer programs and services 1711 Center Ave. West designed to provide support, encouragement, Dilworth, MN 56529 information and self-management skills that aid www.axisclinicialsusa.com/labservices a person with pain regain control of their life. AXIS Toxicology & Clinical Lab Services is 800.533.3231 or theacpa.org a full-service clinical laboratory specializing in compliant-based medication monitoring BOOTH 503 of controlled prescription drugs and illicit Amgen Inc. substances. Education is our difference. AXIS consults with top attorneys and educators in the One Amgen Center Drive pain industry to offer cutting-edge education to Thousand Oaks, CA 91320 its clients. www.amgen.com Amgen is committed to unlocking the potential of biology for patients suffering from BOOTH 509 Celling Biosciences serious illnesses by discovering, developing, manufacturing and delivering innovative human 4719 S Congress Ave therapeutics. This approach begins by using Austin, TX 78745 tools like advanced human genetics to unravel the complexities of disease and understand the BOOTH 217 fundamentals of human biology. Chesapeake Research Group 8030-B Ritchie Hwy. BOOTH 301 Pasadena, MD 21122 AnaBios Established in 2004 by Dr. Ira Gottlieb and 3030 Bunker Hill St. Deborah Tunick, RN, Chesapeake Research San Diego, CA 92109 Group has completed more than 60 clinical trials. www.anabios.com Our unparalleled expertise in clinical research AnaBios helps ensure the safety and efficacy has earned us a reputation for conducting clinical of novel therapeutics through its advanced studies in acute, chronic, and neuropathic pain human-focused translational technologies. that have consistently delivered quality results. Unmatched access to viable human tissue and By conducting Phase I–IV, in- and out-patient research capabilities, combined with insights studies, we have helped sponsors reach their from its experienced team of scientists means goals of getting many new medications on the AnaBios offers the unprecedented opportunity to market. predict human clinical responses for promising compounds. APS 2018 SCIENTIFIC SUMMIT 25 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibitor Listing BOOTH 203 BOOTH 511 Cincinnati Children's Hospital Global Gadgets 3333 Burnet Avenue 3651 Lindel Rd. Cincinnati, OH 45229 #D744 www.cincinnatichildrens.org Las Vegas, NV 89103 Cincinnati Children's Hospital weaves world-class www.globalgadgetsus.com clinical care with ground-breaking basic science and clinical research, seamlessly integrating the BOOTH 507 understanding and treatment of pediatric pain. Harvard MedTech, LLC The 11 expert researchers within Cincinnati 6280 S. Valley View Blvd. Children's Consortium for Understanding Pediatric Pain conduct cutting-edge, Ste 412 comprehensive, multidisciplinary, pediatric pain Las Vegas, NV 89118 research in state-of-the-art research facilities. www.harvardmedtech.com Harvard MedTech is a breakthrough health BOOTH 303 technology and services company that provides Daiichi Sankyo, Inc. smart devices and empowering personalized patient services within the home. Each treatment 211 Mt. Airy Rd. innovation for chronic pain and musculoskeletal Basking Ridge, NJ 7920 disorders is physician-driven and patient-centric. www.dsi.com Physicians add exceptional patient care and Daiichi Sankyo, Inc. is the U.S. subsidiary of ancillary practice revenue without expanding Daiichi Sankyo, Co., Ltd. The Company currently hours or overhead. markets therapies in hypertension, dyslipidemia, diabetes, acute coronary syndrome, thrombotic disorders, stroke risk reduction, opioid-induced constipation, IV iron therapy, and metastatic BOOTH 414 melanoma. Intent Solutions 730 Peachtreee Street, NE, Ste. 550 BOOTH 215 Atlanta, GA 30308 ExpertMRI www.intentsolutions.com 9500 E Artesia Blvd. Bellflower, CA 90706 BOOTH 114 www.epertmri.com International Association for the Study of Pain (IASP) By creating quality imaging techniques to help diagnose patients in symptomatic positions 1510 H Street NW, Suite 600 utilizing both the multipositional/weight-bearing Washington, DC 20005 MRI as well as High Field Strength MRI units, iasp-pain.org we have placed ourselves in the forefront of IASP is the leading professional forum for radiology and orthopedic research. Expert MRI science, practice, and education in the field has centers located throughout California and is of pain. Membership is open to trainees and the leading provider of medical-legal MRIs in the professionals worldwide involved in research, state. diagnosis, prevention, and treatment of pain. Join us for the 17th World Congress on Pain, September 12–16, in Boston, MA. BOOTH 118 Karuna Labs 525 York St. San Francisco, CA 94110 www.chronicpain.io APS 2018 SCIENTIFIC SUMMIT 26 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibitor Listing BOOTH 310 BOOTH 201 LabCorp/MedTox Medoc Advanced Medical Systems 531 S. Spring Street 1502 W NC Highway 54, #404 Burlington, NC 27215 Durham, NC 27707 www.labcorp.com www.medoc-web.com LabCorp MedWatch® is one of the nation’s Exhibiting our Q-Sense CPM System for versatile, premier medical drug monitoring programs and easy-to-administer evaluation of Conditioned is offered through LabCorp and its specialty Pain Modulation (CPM). Q-Sense CPM joins testing laboratory, MedTox Laboratories. The our offering of thermal, algometry, and fMRI LabCorp MedWatch® program offers a full menu stimulation systems for clinical research of medical drug monitoring tests that provides pharmacologic trial and clinic settings. Get a unparalleled choice, flexibility, and clinical value "sneak peek" of an upcoming new offering to our for your specific monitoring needs. line of fMRI thermal stimulators. BOOTH 408 BOOTH 416 LightForce Therapy Lasers by LiteCure NCCIH/NIH Medical 530 Gatheir Rd. 250 Corporate Blvd, Suite B Ste 500 Newark, DE 19702 Rockville, MD 20850 www.lightforcelasers.com www.nccih.nih.gov LightForce Therapy Lasers by LiteCure Medical are the most advanced Deep Tissue Therapy BOOTH 202 Lasers available. Committed to innovation Pain Medicine News and science, LiteCure Medical is constantly 545 W. 45th St. conducting scientific studies and providing educational opportunities. Get your patients back 8th Floor in action with the therapeutic power of LightForce New York, NY 10036 Deep Tissue Therapy Lasers. www.painmedicinenews.com Pain Medicine News (PMN), the best-read pain BOOTH 404 publication in the United States according to Lotus Clinical Research Kantar Media, is mailed 10 times annually to 47,440 pain-treating physicians. This newspaper 100 W California Blvd. offers extensive coverage of pain-related #25 presentations at major clinical meetings and Pasadena, CA 91105 feature articles on topics relevant to practicing www.lotuscr.com clinicians. PMN also presents in-depth clinical Lotus Clinical Research is a specialty analgesic and educational reviews written by thought CRO and research site supporting all phases of leaders, as well as cutting-edge practice discovery for analgesic treatments, focused on management articles improving the scientific accuracy of analgesic programs. Led by Dr. Neil Singla, Lotus focuses on optimizing design/conduct of clinical trials in pain, providing scientific leadership throughout the development process. APS 2018 SCIENTIFIC SUMMIT 27 A M E R I C A N P A I N S O C I E T Y. O R G
Exhibitor Listing BOOTH 409–411 BOOTH 102 Premier Research The Journal of Pain 1 Park Drive c/0 5 Woodland Drive NE Suite 150 Iowa City, Iowa 52240 Research Triangle Park, NC 27709 www.jpain.org www.premier-research.com The Journal of Pain, official journal of the Premier Research is a leading clinical American Pain Society, publishes original articles development service provider that helps related to all aspects of pain, including clinical highly innovative biotech, specialty pharma, and basic research, patient care, education, and and medical device companies transform health policy. The Journal aims to improve the breakthrough ideas into reality. The company has care of patients in pain by providing a forum for a wealth of experience in the execution of global, clinical and basic research. regional, and local clinical development programs with a special focus on addressing unmet needs BOOTH 116 in areas such as analgesia, dermatology, medical Thorp Institute device, neuroscience, oncology, pediatrics, and 317 N. El Camino Real rare disease. Premier Research operates in 84 Ste 407 countries and employs 1,100 professionals, including a strong international network of clinical Encinitas, CA 92024 monitors and project managers, regulatory, data www.thorpinstitute.com management, statistical, scientific, and medical experts. They are focused on smart study design BOOTH 308 for advanced medicines that allow life-changing U.S. Pain Foundation treatments. 670 Newfield St. Ste B BOOTH 410 Middletown, CT 6457 Syneos Health www.uspainfoundation.org 3201 Beechleaf Court Suite 600 BOOTH 112 Raleigh, NC 27604 Wolters Kluwer www.syneoshealth.com 2001 Market Street Syneos Health (Nasdaq:SYNH) is the only Philadelphia, PA 19103 fully integrated biopharmaceutical solutions www.lww.com organization. Our company, including a Contract Wolters Kluwer Health is a leading global provider Research Organization (CRO) and Contract of information and point-of-care solutions for the Commercial Organization (CCO), is purpose-built healthcare industry. Our solutions are designed to accelerate customer performance to address to help professionals build clinical competency modern market realities. Created through the and improve practice so they can make important merger of two industry leading companies—INC decisions on patient care. Our leading product Research and inVentiv Health—we bring together brands include Audio-Digest, Lippincott, Ovid®, more than 21,000 clinical and commercial minds UpToDate®, and others. with the ability to support customers in more than 110 countries. APS 2018 SCIENTIFIC SUMMIT 28 A M E R I C A N P A I N S O C I E T Y. O R G
BeƩer Science. Superior Results. Analgesic CRO Focused on improving the scienƟc accuracy of analgesic programs www.LotusCR.com Booth #404
Full Schedule SUNDAY, MARCH 4 8 am–Noon A Patient-Oriented Approach to Navigating the Transition from Acute to Chronic Pain: A Fundamental Course 4.0 hours CE credit available Charles Argoff, MD; Burel Goodin, PhD; Theodore Price, PhD Magic Kingdom Ballroom 2 OBJECTIVES: 1. Understand how neuronal plasticity contributes to the development of chronic pain. 2. Obtain a greater appreciation of psychosocial contributors from acute to high impact chronic pain. 3. Understand how basic science findings will apply to new treatments that will prevent the transition from acute to chronic pain. 8 am–Noon Six Building Blocks Workshop: Implementing Team-Based Management of Chronic Opioid Therapy 4.0 hours CE credit available David Tauben, MD; Laura-Mae Baldwin, MD; Jessica Merlin, MD PhD; Mark Stephens Castle OBJECTIVES: 1. Identify the six key components of a clinic process for improving management of chronic opiod therapy. 2. List fundamental features of clinic policies and patient agreements that support improvement in managing chronic opioid therapy. 3. Name the data elements important for measuring success in improving management of chronic opioid therapy. 4. Identify the next steps a clinic could take to improve management of chronic opioid therapy. 8 am–4:30 pm APS Conference on Analgesic Trials Robert Dworkin, PhD; Neil Singla, MD; Robert Rappaport, MD; Nathaniel Katz, MD; John Farrar, MD PhD; Roy Freeman, MD; Ralf Baron, MD Magic Kingdom Ballroom 1 and 4 1–4:15 pm Early Career Forum South Ballroom 4:30–6 pm Early Career Professional/Mentor Reception Sleeping Beauty Pavilion 6–7:30 pm Clinical and Basic Science Data Blitz Kathryn Braden, Ashley M. Cowie, Aleisha Khan, Francie Moehring, Myriam Paquet, Rachna Sannegowda, John Streicher, Xin Zhang Magic Kingdom Ballroom 2 B Basic Science C Clinical T Translational 30 A M E R I C A N P A I N S O C I E T Y. O R G
Full Schedule SUNDAY, MARCH 4 7:30–9 pm Basic Science Dinner Scientific Communication: Thinking Outside of the Peer Review Box Joe Palca; Theodore J. Price, PhD; Stephani Sutherland, PhD Magic Kingdom Ballroom 1 and 4 MONDAY, MARCH 5 6–7 am Yoga Sleeping Beauty Pavilion APS requests that participants make a donation to the Pain Research Fund. 7–7:30 am Posters and Breakfast Experience Exchange 7:30–8 am Gathering and Welcome Center Ballroom 8–8:30 am | Plenary Lecture The Biology of Infant and Childhood Pain: It All Begins Here 0.5 hours CE credit available Maria Fitzgerald, FMedSci FRS Center Ballroom OBJECTIVES: 1. Explain the importance of understanding the basic developmental biology of pain pathways when assessing infant pain. 2. Compare and contrast ‘brain-based’ and ‘behavioral-based’ approaches to clinical pain assessment and analgesic management in infants. 3. Show that brain activity following noxious procedures differs in individual infants depending on sex, gestational age, and levels of physiological stress. 8:30–9 am | Plenary Lecture Variability in the Pain Experience After Injury 0.5 hours CE credit available James C. Eisenach, MD Center Ballroom OBJECTIVES: 1. Approach the problem of chronic pain after surgery as a process rather than a disease. 2. Better predict the risk of slow recovery after surgery in their patients. 3. Avoid using drug treatments which show no benefit to speed recovery after surgery. B Basic Science C Clinical T Translational 31 A M E R I C A N P A I N S O C I E T Y. O R G
Full Schedule MONDAY, MARCH 5 9:15–10:45 am | Concurrent Symposia 1.5 hours CE credit available Putting the Spotlight on Social: An Innovative Multidisciplinary, Multispecies Approach for Examining the Influence of Social Context in Pain T Kristen E. Jastrowski Mano, PhD (Moderator); Loren Martin, PhD; Kai Karos, MSc Magic Kingdom Ballroom 1 and 4 OBJECTIVES: 1. Specify the neural circuits and molecular targets for the social modulation of pain. 2. Describe the influence of social threat on the perception and expression of pain, aggression, and empathy. 3. Explain how attentional bias to social threat represents an important mechanism implicated in the co-occurrence of chronic pain and anxiety. Migraine and Sleep Deficiency in Adolescents: Understanding Shared Mechanisms from Bench to Bedside T Emily F. Law, PhD (Moderator); Christopher D. King, PhD; Paul L. Durham, PhD Magic Kingdom Ballroom 2 OBJECTIVES: 1. Describe the impact of sleep deprivation on changes in the trigeminal pathway associated with the development and persistence of pain in animal models of migraine. 2. Identify alterations in structural and functional brain imaging that are related to migraine frequency and sleep deficiency in adolescents with chronic migraine. 3. Understand the impact of cognitive-behavioral therapy for insomnia on migraine frequency in adolescents with co-occurring chronic migraine and insomnia. Psychological Treatments for Chronic Pain: Who Benefits & Why? C Melissa Day, PhD (Moderator); Beverly E. Thorn, PhD; Mark P. Jensen, PhD Center Ballroom OBJECTIVES: 1. Describe two theoretical mechanism frameworks for understanding for whom various psychosocial treatments are expected to be of benefit and how this benefit is engendered. 2. Understand the theory-driven moderators and mediators of pain education, cognitive and cognitive-behavioral therapy, hypnosis, hypnotic cognitive therapy, mindfulness-meditation, and mindfulness-based cognitive therapy. 3. Develop patient-treatment matching algorithms to guide clinical decision making regarding which patients are most likely to benefit from the various interventions discussed. B Basic Science C Clinical T Translational 32 A M E R I C A N P A I N S O C I E T Y. O R G
Full Schedule MONDAY, MARCH 5 Exploiting Cellular and Molecular Mechanisms of Neuroinflammation for New Treatments of Chronic Pain B Jelena Janjic, PhD (Moderator); Theodore J. Price, PhD; Edgar Alfonso Romero-Sandoval, MD PhD South Ballroom OBJECTIVES: 1. Identify cellular and molecular targets in neuroinflammation with potential for new chronic pain therapy development. 2. Examine interconnected and distinct approaches to immunomodulation that can be utilized for targeting neuroinflammation based on specific mechanistic findings. 3. Interpret distinct findings from pharmacological, genetic, and nanotechnology-based approaches to discovery of new therapeutic targets in neuroinflammation. 11 am–Noon | Shared Interest Group Meetings Measurement of Pain and Its Impact/Geriatric Pain/Nursing 1.0 hour CE credit available Elizabeth Felix, PhD; Keela Herr, RN FAAN PhD; Sue Marden, PhD; Joseph Riley III, PhD Measurement of Pain and Its Impact Co-chairs: Yensiel Cruz-Almeida, PhD MSPH; Elizabeth Roy Felix, PhD Geriatric Pain Co-chairs: Yenisel Cruz-Almeida, MS PhD; Ellen Terry, PhD Nursing Co-chairs: Janet Van Cleave, RN PhD; Staja Booker, RN MS Center Ballroom OBJECTIVES: 1. Describe mechanism-based approaches as the rationale for specific pain assessment and management in older individuals. 2. Discuss comprehensive and specific assessment approaches for older patients with complex co-morbidities, and experiencing acute and/or persistent pain in common clinical settings. 3. Describe the Person-Centered Assessment Resource Initiative (1U2CCA186878-01) funded by the National Institutes of Health to sustain a research infrastructure that will educate and enable researchers and other interested health professionals on the use and interpretation of person-centered health outcomes, including pain. Pain and Disparities 1.0 hour CE credit available Mary Driscoll, PhD; Beverly Thorn, PhD Chair: Vani A. Mathur, PhD Vice Chair: Raimi Quilton, PhD Board Members: Kate A. Yeager, PhD MS RN; Eryka Boyd; Mary Janevic South Ballroom OBJECTIVES: 1. Review major disparities in pain experience. 2. Highlight potential mechanisms of pain disparities, with particular focus on potential targets for interventions to decrease disparities. 3. Discuss two current interventions designed for under-served populations: Behind the scenes considerations. 4. Discuss cross-cutting issues (e.g., how aspects of intersectionality might moderate effects of interventions, how research across multiple disciplines can inform this work). B Basic Science C Clinical T Translational 33 A M E R I C A N P A I N S O C I E T Y. O R G
Full Schedule MONDAY, MARCH 5 Pain in Sickle Cell Disease Business Meeting No CE credit available Wally Smith, PISCEs Chair: Carlton Dampier, MD Magic Kingdom Ballroom 1 and 4 The Pain in Sickle Cell Disease SIG seeks to foster the development of a multidisciplinary community that brings together pain researchers, including basic scientists, clinicians, nurses, psychologists, and other health professionals to increase the understanding of pain in sickle cell disease and its treatment. An update on the SIG's collaborative activities with the ACTTION-APS AAPM Pain Taxonomy Project and the ASH SCD Coalition will be provided at the SIG meeting, followed by a discussion of the draft Acute Pain Taxonomy and new analyses of data from the PISCEs study. Headache Business Meeting No CE credit available Chair: Gregory Dussor, PhD Magic Kingdom Ballroom 2 This SIG will expand the focus on headache within APS and seek to increase membership by those interested in headache. It will encompass interest in any disorder falling under the umbrella term headache including but not limited to migraine, cluster headache, tension-type headache, chronic daily headache, medication-overuse headache etc. Genetics and Pain Business Meeting No CE credit available Chair: Shad Smith, PhD; Co-chair: Vidya Chidambaran, MD Monorail This year the APS Genetics and Pain SIG will present awards to recognize Young Investigators for outstanding research on genetics and pain. These awards will highlight posters that best represent the theme of this year's meeting of Understanding Pain Mechanisms through genetic tools and discoveries. The Genetics and Pain SIG meeting will feature short presentations from the winners of the poster awards. After the poster talks, we will also take the opportunity to discuss SIG business regarding leadership changes, educational opportunities, collaborative research efforts, and goals for the coming year. 11 am–Noon Essential Legal Concepts to Avoiding Lawsuits, Reducing Taxes and Protecting Your License No CE credit available Art McOmber, Legally Mine, Inc. Castle Through this course attendees will truly understand exactly how, why, and where legal entities should be used for both lawsuit prevention and income tax reduction. Our course is both engaging and easy to understand. When completed, attendees will have an understanding of the proper use of legal tools, and will have an organized approach to taking effective action. 12:15–1:15 pm Lunch; Exhibits; Education; and Author-Attended, Odd-Numbered Posters Experience Exchange B Basic Science C Clinical T Translational 34 A M E R I C A N P A I N S O C I E T Y. O R G
Full Schedule MONDAY, MARCH 5 12:15–12:35 pm The (Mis)Socialization of Children's Pain Memories Melanie Noel, PhD Solutions Theater 12:55–1:15 pm Hazardous Alcohol and Opioid Use in Chronic Pain: An Assessment of Frequency and Impact Kevin Vowles, PhD Solutions Theater 1:30–2 pm | Plenary Lecture Spinal Mechanisms of Spinal Cord Injury–Induced Neuropathic Pain: Implications for Novel Therapeutic Targets 0.5 hours of CE credit available Susan G. Dorsey, PhD RN FAAN Center Ballroom OBJECTIVES: 1. Describe the difference between neuropathic and nociceptive pain. 2. Discuss how novel therapeutic targets can be identified and researched. 3. Identify potential barriers to translation of novel therapeutic targets. 2–2:30 pm | Plenary Lecture Assessment and Management of Neuropathic Pain: Advances, Challenges, and Opportunities 0.5 hours of CE credit available Srinivasa N. Raja, MD Center Ballroom OBJECTIVES: 1. Recognize the prevalence of neuropathic pain and assess and differentiate neuropathic pain from nociceptive pain. 2. Discuss evidence-based pharmacologic and interventional treatment options for neuropathic pain with your patients. 3. Recognize the limitations in effectiveness of present pharmacological therapies and develop multimodal strategies for personalizing the treatment for a given patient. 2:45–4:15 pm | Concurrent Symposia 1.5 hours of CE credit available Novel Mechanisms Underlying Risk for Acute and Chronic Postsurgical Pain: Role of Peripheral Pain Processing, Central Sensitization, and Genomics C Vidya Chidambaran, MD (Moderator); Jennifer A. Rabbitts, MD; Chad M. Brummett, MD Magic Kingdom Ballroom 1 and 4 OBJECTIVES: 1. Characterize the relationship between pain processing phenotypes (quantitative sensory testing) and psychosocial factors and the development of chronic postsurgical pain in children undergoing major surgery. 2. Describe the impact of centralized pain on acute and chronic pain outcomes in adults after major surgery. 3. Discuss genomics, gene-environmental interactions, and epigenetic factors influencing acute and chronic postsurgical pain, and opioid responses in children and adolescents undergoing major surgery. B Basic Science C Clinical T Translational 35 A M E R I C A N P A I N S O C I E T Y. O R G
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