MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi

Page created by Ellen Gill
 
CONTINUE READING
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
MEDICAL
IMAGING
TECHNICAL PROGRAM

  TEXAS
           15–20 February 2020
 IN 2020
           Marriott Marquis Houston
           Houston, Texas, USA

spie.org/mi

#SPIEMedicalImaging
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Marriott Marquis Houston

       LEVEL 3
                                                                      SUGARLAND         CLEAR LAKE

            Download the                                                                                                 ELEVATORS &
            SPIE Conference App                                      TANGLEWOOD          MEMORIAL                        ESCALATORS

                                                                                         MONTROSE

                                         PREFUNCTION                                                                                      HUNTERS
                                                                                                                                           CREEK

                        MEYERLAND        BRIARGROVE       KINGWOOD                  RIVER OAKS
                                                                                                     VESTI-      PARKER        GALLERIA
         WESTCHASE                                                                                   BULE      BOARDROOM      BOARDROOM

       LEVEL 4

                                                                          SALON A

                                                                                                          ELEVATORS &
         PLENARY AND                                                                                      ESCALATORS
                                    POSTERS & DEMOS                       SALON B
           LUNCHES

                                                                          SALON C

              SALON F                      SALON D/E
                                                                                                      AV SPEAKER
                                                                                                     CHECK-IN DESK
                                    COFFEE SERVICE
                                                                                                              DAVID MITZNER

                             BOOKSTORE                  ALREADY                     REGISTRATION/
                                                       REGISTERED                      CASHIER
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
CONNECTING MINDS.
                                                                                         ADVANCING LIGHT.

MEDICAL
IMAGING 2020
THE PREMIER EVENT FOR THE SCIENCE
BEHIND MEDICAL IMAGING
15–20 February 2020
Marriott Marquis Houston
Houston, Texas, USA

CUTTING-EDGE RESEARCH

WORLD-CLASS SPEAKERS

TRAINING AND EDUCATION

FOCUSED TECHNICAL TOPICS

spie.org/mi
#SPIEMedicalImaging

SPIE is the international society for optics and photonics, an educational not-for-profit organization founded
in 1955 to advance light-based science, engineering, and technology. SPIE provided more than $5 million in
support of education and outreach programs in 2019.
SPIE would like to express its deepest appreciation to the symposium chairs, conference chairs, program
committees, session chairs, and authors who have so generously given their time and advice to make this
symposium possible.

           New data laws mean you must opt in: Please sign up to receive
           email updates about this event — www.spie.org/signup
                                                                                                                 1
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Welcome to SPIE Medical Imaging 2020

    Conferences:              Hear 1,000 presentations on the full range of medical imaging modalities including medical image acquisition, display, processing,
    analysis, perception, decision support, and informatics.
                                                 11312         Physics of Medical Imaging (Chen, Bosmans, Zhao). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
                                                 11313         Image Processing (Išgum, Landman) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
                                                 11314         Computer-Aided Diagnosis (Hahn, Mazurowski). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
                                                 11315         Image-Guided Procedures, Robotic Interventions, and Modeling (Fei, Linte) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
                                                 11316         Image Perception, Observer Performance, and Technology Assessment (Samuelson, Taylor-Phillips) . . . . . . . . . 32
                                                 11317         Biomedical Applications in Molecular, Structural, and Functional Imaging (Gimi, Krol) . . . . . . . . . . . . . . . . . . . . . . 33
                                                 11318         Imaging Informatics for Healthcare, Research, and Applications (Chen, Deserno). . . . . . . . . . . . . . . . . . . . . . . . . . . 33
                                                 11319         Ultrasonic Imaging and Tomography (Byram, Ruiter) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
                                                 11320         Digital Pathology (Tomaszewski, Ward). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

    Courses: Get focused, efficient training on current approaches in medical imaging and deep learning, AI, photon counting, and many more, that you
    can apply directly to your daily work. Register soon to ensure a spot.
                                                 SC086 Fundamentals of Medical Image Processing and                                                         SC1292 Technological Assessment of X-Ray Based NEW
                                                       Analysis (Deserno) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  20                    Breast Imaging Systems Using Anthropomorphic
                                                 SC1129 Photon Counting CT (Danielsson, Sjölin) . . . . . . . . . . . . . .  20                                    Phantoms (Glick, Bosmans, Badal) . . . . . . . . . . . . . . . . . . . . 22

                                                 SC1235 Introduction to Medical Image Analysis Using                                                        SC1295 From Analytic to Clinical Validation: NEW
                                                        Convolutional Neural Networks (Wenzel) . . . . . . . . . . . . . 21                                        Moving AI/ML into Practice (Hsu, Brown, Nishikawa,
                                                                                                                                                                   Krupinski) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
                                                 SC1183 Modern Diagnostic X-ray Sources (Behling)  . . . . . . . . . . . 21
                                                                                                                                                            SC987 Spectral CT Imaging NEW (Schmidt, Flohr, Grant) . . . . . . . 24
                                                 SC1239 Virtual Clinical Trials: An In-depth Tutorial
                                                        (Maidment, Bakic, Barufaldi) . . . . . . . . . . . . . . . . . . . . . . . . . . 21                 SC1296 High-Performance Computing for Medical Imaging on
                                                                                                                                                                   Graphics Processing Units (GPU) with CUDA (Caucci) . . 24
                                                 SC1262 Adversarial Networks: From Architecture
                                                        to Practical Training (Wenzel) . . . . . . . . . . . . . . . . . . . . . . . . 22

                                                 DAILY EVENT SCHEDULE . . . . . . . . . . . . . . . . . . . . . . . . . . . 16-17                           GENERAL INFORMATION . . . . . . . . . . . . . . . . . . . . . . . . . . 91-92
                                                 DAILY CONFERENCE SCHEDULE . . . . . . . . . . . . . . . . . 26-30                                          Registration · Author/Presenter Information
                                                                                                                                                            Food and Beverage · Onsite Services · Parking and Car Rental
                                                 PROCEEDINGS  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
                                                                                                                                                            SPIE POLICIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94-95
                                                 INDEX OF AUTHORS, CHAIRS, AND
                                                 COMMITTEE MEMBERS  . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73-88

2                                               SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Plenary and Keynote Sessions. . . . . . . . . . .  5–9
                                              Don’t miss these world-class speakers discussing the latest
                                              advancements and most promising breakthroughs.

                                              Technical Events. . . . . . . . . . . . . . . . . . . . . . .  10–12
                                              Join your peers and colleagues in group discussions around focused
                                              technical topics, various workshops, live demos, and at the interactive
                                              poster sessions.

                                              Social + Networking Events. . . . . . . . . . . . . . . . 13
                                              Join your colleagues at various events, including the Student Dessert
                                              with the Experts, Women’s Networking Lunch—events not to be missed!

                                              Award Events + Student Information. . . .  14–15
                                              Participate in the following opportunities: RFW All-Conference Best Student Paper,
                                              Young Scientist Award, Student Paper Award, as well as information about Poster Awards.

                                                                                                                Download the
                                                                                                                SPIE Conference App

THIS PDF PROGRAM IS CURRENT AS OF 20 JANUARY 2020. Find complete, up-to-date information and create your personalized schedule at spie.org/mi   3
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
EXECUTIVE ORGANIZING
COMMITTEE
Hilde Bosmans, Katholieke Univ. Leuven
  (Belgium)
Brett C. Byram, Vanderbilt Univ. (USA)
Po-Hao Chen, Cleveland Clinic (USA)
Guang-Hong Chen, Univ. of Wisconsin-
  Madison (USA)
Thomas M. Deserno, Technische Univ.
  Braunschweig (Germany)
Baowei Fei, The Univ. of Texas at Dallas, The
  Univ. of Texas Southwestern Medical Ctr.
  (USA)
Barjor Gimi, Cooper Medical School, Rowan
  Univ. (USA)
Horst K. Hahn, Fraunhofer MEVIS (Germany)
Ivana Išgum, Univ. Medical Ctr. Utrecht
  (Netherlands)
Andrzej Krol, SUNY Upstate Medical Univ.
                                                Welcome to
  (USA)
                                                SPIE Medical Imaging is the internationally recognized forum for reporting state-of-the-art research
Bennett A. Landman, Vanderbilt Univ. (USA)
                                                and development in medical imaging. The event focuses on the latest innovations found in underlying
Cristian A. Linte, Rochester Institute of
  Technology (USA)                              fundamental scientific principles, technology developments, scientific evaluation, and clinical
Maciej A. Mazurowski, Duke Univ. (USA)          application. The symposium covers the full range of medical imaging modalities including image
Nicole V. Ruiter, Karlsruher Institut für       processing, physics, computer-aided diagnosis, perception, image-guided procedures, biomedical
  Technologie (Germany)
                                                applications, ultrasound, informatics, radiology and digital pathology, with an increased focus on fast
Frank W. Samuelson, U.S. Food and Drug
  Administration (USA)                          emerging areas like deep learning, AI, and machine learning. The event offers the latest advances
Sian Taylor-Phillips, The Univ. of Warwick      covered in nine conference topics.
  (United Kingdom)
John E. Tomaszewski, Univ. at Buffalo (USA)     Join your peers where collaboration brings ideas to life and technology to market. Hear the work,
Aaron D. Ward, The Univ. of Western             network with leaders in the field, and see the applications of the future. We look forward to seeing
  Ontario (Canada)
                                                you in Houston!
Wei Zhao, Stony Brook Medicine (USA)

COOPERATING ORGANIZATIONS
AAPM—American Association of Physicists         Symposium Chairs:
   in Medicine
IFCARS—International Foundation for                           Georgia D. Tourassi                              Metin N. Gurcan
   Computer Assisted Radiology and Surgery                    Oak Ridge National                               Wake Forest Baptist Medical
                                                              Lab. (USA)                                       Ctr. (USA)
MIPS—Medical Image Perception Society
SIIM—Society for Imaging Informatics in
   Medicine
WMIS—World Molecular Imaging Society

PROMOTIONAL PARTNERS
Biophotonics, a Photonics Media Publication
Electro Optics Magazine
optics.org
Photonics Online
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Awards and Plenary Session
Don’t miss these world-class speakers discussing the latest directions and most promising breakthroughs.

Monday 17 February 2020 • 4:00 PM - 5:15 PM                    4:30 PM
Location: Salon F
                                                               Plenary Presentation
4:00 PM
                                                               ARE TODAY’S MIXED REALITY EXPERIENCE PILLARS AND
WELCOME AND NEW SPIE FELLOWS                                   HARDWARE ARCHITECTURES WELL ALIGNED WITH THE
ACKNOWLEDGEMENTS                                               SPECIFIC NEEDS OF MEDICAL IMAGING AND SURGICAL GUIDANCE?
                                                                                  Bernard Kress
4:15 PM                                                                           Principal Optical Architect, HoloLens team
                                                                                  Microsoft Corp. (USA)
BEST STUDENT PAPER AWARDS
                                                                                   Mixed Reality (MR) headsets have the potential to revolutionize the way we work,
ANNOUNCEMENT                                                                       learn, communicate, and get entertained. The main pillars for MR development
The first place winner and runner up of the Robert F. Wagner                       are wearable, visual and social comfort, as well as immersion experience. Do
All-Conference Student Paper Award will be announced.          these pillars intersect the specific needs of medical imaging and surgical guidance applications?
                                                               We will review the various challenges to implement MR hardware specifically adapted to such tasks
                                                               with today’s start of the art MR headset technology.
4:20 PM                                                        Biography: Bernard Kress has been involved in AR, VR, and MR technology for the past decade,
                                                               specifically focussing on hardware issues such as optics, optical architectures and related tech-
SPIE HARRISON H. BARRETT AWARD IN                              nologies as well as sensors (depth mapping, head and eye tracking, gesture sensing). Bernard
MEDICAL IMAGING                                                published various books and book chapters and authored more than 100 papers on this topics
This award will be presented in recognition of outstanding     and holds 50+ international patents on related technologies.
accomplishments in medical imaging.                            He has been involved in the Google Glass project at Google X Labs since its infancy in 2010, as the
                                                               principal optical architect, and later joined the HoloLens Team at Microsoft in 2015 as the Partner
                                                               Optical Architect. He is in charge of shaping the next generation mixed reality optical hardware
                                                               architectures at HoloLens. He is also a board member and fellow of the SPIE, and conference chair
                                                               for various SPIE and OSA conferences related to AR, VR, and MR.
                                                               His passion for the tremendous potential of artificial intelligence in medicine resulted in more than
                                                               90 publications spanning a range of topics from novel deep learning and Bayesian approaches for
                                                               quantification to real-world applications in the clinic.                                                5
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Special Events • Keynote Presentations
    IMAGING INFORMATICS FOR HEALTHCARE, RESEARCH,                              IMAGING INFORMATICS FOR HEALTHCARE, RESEARCH,                              PHYSICS OF MEDICAL IMAGING
    AND APPLICATIONS                                                           AND APPLICATIONS                                                           Conference 11312 Monday Keynote Presentation
    Conference 11318 Sunday Keynote Presentation                               Conference 11318 Monday Keynote Presentation                               Monday 17 February 2020 • 10:10 AM - 10:50 AM
    Sunday 16 February 2020 • 3:30 PM - 4:30 PM                                Monday 17 February 2020 • 8:00 AM - 8:40 AM                                Location: Salon A
    Location: River Oaks                                                       Location: River Oaks
                                                                                                                                                          Innovations and translation in molecular
    Cybersecurity in healthcare: is our                                        Shining light into the machine learning                                    PET/MR and PET/CT
    patients’ health now at risk?                                              “black box”: the state of explainable AI                                                      Georges El Fakhri
                      Dr. Jim Whitfill                                                           William Hsu                                                                 Massachusetts General Hospital and
                      HonorHealth and Society for Imaging                                        Univ. of California, Los Angeles (USA)                                      Harvard Medical School (USA)
                      Informatics (USA)
                                                                                                Abstract: The rapid advancement of artificial intel-                         Abstract: In this talk, recent developments in Pos-
                      Abstract: The cybersecurity landscape continues to                        ligence (AI) and machine learning (ML) techniques                            itron Emission Tomography (PET) and Magnetic
                      rapidly evolve across all industries including health-                    has yielded models whose sensitivity and specificity                         Resonance Imaging (MRI) are explored and the
                      care. Unique to healthcare, however, is the fact that                     rival those of trained human experts. However, as                            challenges of simultaneous imaging in PET/MR and
                      patients lives can be impacted by simply altering                         these models transition from proofs-of-concept to                            PET/CT as well as the opportunities afforded by two
                      or withholding information. This is session we will      decision support tools that are used clinically, model developers and      modalities are discussed. The unique sensitivity of PET (picomolar)
    look at the evolution of attacks on personal information, to personal      the end-users who interact with them should have a clear appreciation      and its quantitative capabilities can be associated with the superb
    health information to personal heath. In addition potential methods        of how and what these models are “learning”. Future users of these         spatial and temporal resolution of MR as well as its excellent soft tissue
    to balance sharing of data with protecting patients’ identities will be    models should not see them as a “black box” but demand greater             contrast to provide an ideal imaging modality for many cancers as well
    explored to better understand concepts around federated databases          transparency from model developers in conveying the rationale be-          as cardiac and brain explorations. Improvements in image quality and
    and other anonymization techniques.                                        hind the chosen representation, how the model was trained, and the         diagnostic accuracy are illustrated in specific patient studies in PET/
                                                                               explanation associated with a model’s prediction.                          MR and PET/CT, and synergies between PET and MR spectroscopy are
    Biography: As Chief Transformation Officer, Jim Whitfill, MD, brings
                                                                                                                                                          discussed in the context of guiding radiotherapy. Beyond oncology,
    leadership expertise in healthcare, organizational culture, and infor-     In this talk, I will review current and late-breaking research on the
                                                                                                                                                          applications in cardiac (viability, perfusion) and brain imaging (neuro-
    mation technology to promote a customer-centric experience and             development of explainable machine and deep learning algorithms,
                                                                                                                                                          degenerative disease, traumatic brain injury) are presented including
    offer new ways to deliver more complete, coordinated and accessible        particularly in the areas of computer-aided detection and diagnosis.
                                                                                                                                                          very early imaging of prodromal AD and normal aging, mapping of
    care. He brings together data, technology and marketing to advance         I will present a taxonomy of different types of explanations and
                                                                                                                                                          mitochondrial membrane potential and simultaneous PET/fMRI for
    technical innovations, such as call center technology, CRM systems,        highlight techniques that interrogate the model based on internal
                                                                                                                                                          mapping dopaminergic and serotoninergic neurotransmission.
    apps and digital tools, to give both the customer and caregivers an        structure or the model’s response to perturbations in the input. I will
    enhanced approach to care.                                                 discuss experiences in applying and interpreting the results of these      Biography: Dr. El Fakhri is the Nathaniel & Diana Alpert Professor of
                                                                               techniques drawn from my work in lung and breast cancer screening          Radiology at Harvard Medical School (HMS) and the founding Director
    By focusing the efforts of these business areas and finding the right
                                                                               and other published research. Finally, I will assess the limitations and   of the Gordon Center for Medical Imaging at Massachusetts General
    digital tools, Dr. Whitfill aims to improve the customer journey so
                                                                               opportunities of current work in interpretable AI/ML, emphasizing the      Hospital and HMS with over 150 members. He is also co-Director of
    that it becomes more seamless and focused on the needs of the in-
                                                                               need for visualizations that aid clinical end-users with understanding     the Division of Nuclear Medicine and Molecular Imaging. Dr El Fakhri
    dividual. The goal is to transform the organization into a more patient
                                                                               model outputs and tools for ensuring the validity of model predictions     is an internationally recognized expert in quantitative molecular
    focused and provider friendly health system which better serves the
                                                                               over time.                                                                 imaging (SPECT, PET-CT, and PET-MR) for in vivo assessment of
    surrounding community.
                                                                                                                                                          patho-physiology in brain, cardiac and oncologic diseases. Current
    Before joining HonorHealth, Dr. Whitfill served as chief medical officer   Biography: William Hsu is Associate Professor at University of Cal-
                                                                                                                                                          areas of research include high resolution PET & MR imaging in a range
    for Innovation Care Partners, a clinically integrated network in Phoe-     ifornia, Los Angeles in the Departments of Radiological Sciences,
                                                                                                                                                          of diseases including neurodegenerative disease and traumatic brain
    nix. He also serves as a clinical associate professor in the departments   Bioinformatics, and Bioengineering and a core faculty member with
                                                                                                                                                          injury (amyloid and neurofibrillary tangles), cardiac arrhythmia and
    of Internal Medicine and Biomedical Informatics at the University of       the Medical & Imaging Informatics group. He directs the Integrated
                                                                                                                                                          heart failure (mitochondrial membrane potential), as well as guiding
    Arizona College of Medicine-Phoenix.                                       Diagnostics Shared Resource, an interdepartmental program that
                                                                                                                                                          radiotherapy planning (PET/MRS). He has authored or co-authored
                                                                               catalyzes research and development of computational tools to im-
    Dr. Whitfill previously held or holds advisory board responsibilities at                                                                              over 300 papers and mentored over 100 students, post-docs and
                                                                               prove early detection, diagnosis, and treatment of cancer through the
    GE Healthcare, Philips Healthcare, IDX and KLAS. In July 2018, he began                                                                               faculty. Dr El Fakhri received many awards and honors, including
                                                                               integration and curation of multi-scale data. His research lab focuses
    his term as the board chair of the Society of Imaging Informatics in                                                                                  the Mark Tetalman Award from the Society of Nuclear Medicine, the
                                                                               on adapting and validating novel AI/ML algorithms, towards assist-
    Medicine and is a regular faculty member for the Radiology Society of                                                                                 Dana Foundation Brain and Immuno-Imaging Award, the Howard
                                                                               ing physicians with formulating timely, accurate, and personalized
    North America and the American College of Radiology. He is a founding                                                                                 Hughes Medical Institutes Training Innovation Award and the Edward
                                                                               management strategies for individual patients. He is a Deputy Editor
    member of the HIMSS-SIIM community for Enterprise Imaging.                                                                                            J. Hoffman Award from the Society of Nuclear Medicine and Molecular
                                                                               for the Radiology: Artificial Intelligence journal, a co-editor for the
                                                                                                                                                          Imaging. He was elected Fellow to the SNMMI, AAPM and IEEE for
    Dr. Whitfill received his BA from Princeton University and his MD from     Sensor, Signal, and Imaging Informatics section of the IMIA Yearbook
                                                                                                                                                          “contributions to biological imaging”.
    the University of Pennsylvania. He trained in internal medicine at the     of Medical Informatics, and a working group leader for the American
    Hospital of the University of Pennsylvania, where he also completed        Medical Informatics Association.
    a fellowship in medical informatics.
6                                                                 SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Special Events • Keynote Presentations
IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS,                            ULTRASONIC IMAGING AND TOMOGRAPHY                                                 BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL,
AND MODELING                                                               Conference 11319 Monday Keynote Presentation                                      AND FUNCTIONAL IMAGING
Conference 11315 Monday Keynote Presentation                               Monday 17 February 2020 • 2:40 PM - 3:40 PM                                       Conference 11317 Tuesday Keynote Presentation
Monday 17 February 2020 • 1:20 PM - 2:20 PM                                Location: Salon C                                                                 Tuesday 18 February 2020 • 10:10 AM - 11:10 AM
Location: Hunter’s Creek                                                                                                                                     Location: River Oaks
                                                                           Quantitative ultrasound successes:
Healthcare in need of innovation:                                          past, present, and future                                                         Label-free molecular imaging with
(exponential) technology and                                                                   Michael Oelze
                                                                                                                                                             spins: a path to high resolution
biomedical entrepreneurship as                                                                 Beckman Institute, Univ. of Illinois (USA)                    through learned subspaces
solution providers                                                                             Abstract: Diagnostic ultrasound is ubiquitous in                                Zhi-Pei Liang
                  Michael Friebe                                                               clinical practice because it is safe, portable, inex-                           Univ. of Illinois (USA)
                  IDTM GmbH, Otto-von-Guericke Univ. Magdeburg                                 pensive, has high spatial resolution and is real time.                           Abstract: Since its invention in the early 1970s,
                  (Germany)                                                                    Therefore, improving the capabilities of diagnostic                              magnetic resonance imaging (MRI) has become a
                                                                                               ultrasound is a highly significant clinically. In this talk                      premier tool for structural imaging and function-
                   Abstract: There are significant challenges in global
                                                                           we will discuss different applications of quantitative ultrasound (QUS)                              al imaging using water proton spin signals. MR
                   healthcare delivery. Some countries have abundant
                                                                           imaging and how QUS approaches have evolved over time. Specifically,                                 spectroscopic imaging (MRSI) has also long been
                   services, but are stuck with a rather nimble and
                                                                           we will discuss the use of spectral-based approaches to estimate the              recognized as a potentially powerful tool for non-invasive, label-free
                   expensive system that focuses on incremental inno-
                                                                           backscatter coefficient (BSC) and attenuation slope and the use of                molecular imaging by exploiting the spin signals from other mole-
                   vations. Other geographies are still in need of basic
                                                                           envelope statistics to describe underlying tissue microstructure. These           cules. However, state-of-the-art MRSI methods, after more than four
tools and infrastructure and require completely different, inexpensive,
                                                                           QUS approaches have been successful at classifying tissue state, mon-             decades of development, still fall far short of providing adequate
and with that more disruptive solutions.
                                                                           itoring focused ultrasound therapy, detecting early response of breast            spatial resolution, speed, and signal-to-noise ratio (SNR) useful for
Healthcare 4.0 with a focus on prevention / early detection and            cancer to neoadjuvant chemotherapy and the automatic detection of                 label-free molecular imaging applications.
pro-active therapy will employ exponential technologies (AI, Big Data,     nerves in the imaging field. We will demonstrate how QUS approaches
Sensor Technology, Synthetic Biology, Robotics, 3D Printing, ...) that     can be incorporated on breast tomography machines, which allow an                 The talk will discuss our recent “breakthroughs” in overcoming the
will surely lead to significant changes in the way we experience and       expansion of the tradeoff between spatial resolution and the variance             long-standing technical barriers of MRSI-based label-free molecular
deliver healthcare, where an empowered patient will play a more and        of QUS estimates. One of the ongoing issues with QUS is the inability             imaging using a new technology known as SPICE (SPectroscopic
more important role.                                                       to properly account for losses in tissues that affect the estimates               Imaging by exploiting spatiospectral CorrElation). SPICE uses a sub-
                                                                           of the backscatter coefficient. We will demonstrate new calibration               space mathematical framework to effectively integrate rapid scanning,
Innovation in that segment can only lead to meaningful solutions                                                                                             sparse sampling, constrained image reconstruction, quantum simula-
if these actually solve a problem and if these problems have been          procedures that can improve the ability to account for tissue losses.
                                                                           Finally, we will discuss how machine learning approaches can further              tion, and machine learning. Preliminary results show an unprecedented
properly studied and understood including the future economics                                                                                               capability for simultaneous mapping of brain structures, function and
and delivery changes. Which leads to the question on whether we            improve QUS techniques by eliminating the need for models and in
                                                                           some cases eliminating the need for a reference scan.                             metabolism using intrinsic spin signals from multiple molecules. In this
actually teach our biomedical engineers the right skills considering                                                                                         talk, I’ll will give an overview of SPICE and also show some “SPICY”
these developments.                                                        Biography: Professor Oelze earned a B.S. in Physics and Mathematics               experimental results we have obtained.
We should introduce a “MEDTEC DESIGN FOR FUTURE HEALTH-                    (1994, Harding University) and Ph.D. in Physics (2000, University
                                                                           of Mississippi). Dr. Oelze joined the faculty of ECE at UIUC in 2005              Biography: Zhi-Pei Liang is currently the Franklin W. Woeltge Profes-
CARE” type program that embraces technological developments,                                                                                                 sor of Electrical and Computer Engineering at the University of Illinois
understands the needs of a future healthcare, teaches entrepreneurial      and serves as a professor and Associate Head. His research interests
                                                                           involve biomedical ultrasound including: quantitative ultrasound,                 at Urbana-Champaign (UIUC). His research is in the general area of
basics and exponential thinking in an interdisciplinary setting.                                                                                             magnetic resonance imaging and spectroscopy, ranging from spin
                                                                           tomography, therapy and beamforming. Dr. Oelze is a fellow of the
Biography: Michael Friebe is a German citizen with expertise in di-        AIUM and a senior member of IEEE. He is a member of the Technical                 physics, signal processing, machine learning, to biomedical applica-
agnostic imaging + image guided therapies, as founder/innovator/           Program Committee of the IEEE Ultrasonics Symposium and serves                    tions. His work has been recognized by a number of awards, including
CEO/investor, and research scientist.                                      as an associate editor-in-chief of IEEE TUFFC, associate editor of                the Sylvia Sorkin Greenfield Award (Medical Physics, 1990), Whitaker
                                                                           Ultrasonic Imaging and associate editor for IEEE TBME.                            Biomedical Engineering Research Award (1991), NSF CAREER Award
Dr. Friebe currently is a research fellow of TUM in Munich, an adjunct
                                                                                                                                                             (1995), Henry Magnuski Scholar Award (UIUC, 1999), University
professor at the Queensland University of Technology in Brisbane,
                                                                                                                                                             Scholar Award (UIUC, 2001), the Otto Schmitt Award (IFMBE, 2012),
and a professor of Image Guided Therapies at Otto-von-Guericke-Uni-
                                                                                                                                                             and the Technical Achievement Award (IEEE-EMBS, 2014). Dr. Liang
versity in Magdeburg, Germany.
                                                                                                                                                             is a Fellow of the IEEE, ISMRM and AIMBE. He was elected to the In-
He is a listed inventor of almost 100 patents, author of >250 scientific                                                                                     ternational Academy of Medical and Biological Engineering in 2012.
contributions, has started well over 20 medical technology start-ups,                                                                                        Dr. Liang served as President of the IEEE-EMBS from 2011-2012 and
is a board member of four medical technology startup companies,                                                                                              received its Distinguished Service Award in 2015.
and an investment partner of a MedTec investment-fund.

                               THIS PDF PROGRAM IS CURRENT AS OF 20 JANUARY 2020. Find complete, up-to-date information and create your personalized schedule at spie.org/mi                                                            7
MEDICAL IMAGING TECHNICAL PROGRAM - spie.org/mi
Special Events • Keynote Presentations
    COMPUTER-AIDED DIAGNOSIS                                                      IMAGE PERCEPTION, OBSERVER PERFORMANCE, AND                               IMAGE PROCESSING
    Conference 11314 Keynote Presentation Tuesday                                 TECHNOLOGY ASSESSMENT                                                     Conference 11313 Wednesday Keynote Presentation
    Tuesday 18 February 2020 • 1:20 PM - 2:20 PM                                  Conference 11316 Wednesday Keynote Presentation                           Wednesday 19 February 2020 • 10:10 AM - 11:10 AM
    Location: Salon B                                                             Wednesday 19 February 2020 • 8:00 AM - 9:00 AM                            Location: Salon C
                                                                                  Location: Briargrove
    Will AI make me a better doctor?                                                                                                                        Bringing machine learning to the
                       Jonathan I. Wiener
                                                                                  Towards understanding perception in                                       clinic: opportunities and challenges
                       Boca Radiology Group and                                   the latest era of AI in medical imaging                                                      Tim Leiner
                       FAU Medical School (USA)
                                                                                                    Maryellen Giger                                                            Univ. Medical Ctr. Utrecht (Netherlands)
                       Abstract: The term “Artificial Intelligence” has                             Univ. of Chicago, (USA)
                                                                                                                                                                                Abstract: Machine learning and especially deep
                       come into such common usage, that it is now used
                                                                                                     Abstract: The study of human perception is as old                          learning hold great promise to improve patient care.
                       interchangeably with any software which automates
                                                                                                     as medical imaging. Understanding perception has                           In several domains, algorithms perform as good as
                       routine tasks. In fact, AI software at its current usage
                                                                                                     yielded the rules of engagement for radiologists                           or better than fellowship trained radiologists for
                       is not intelligent and cannot think out of the box.
                                                                                                     as they tackle the “Where’s Waldo?” situations,                            identification of abnormalities in clinically acquired
    In this lecture, we will explore the history of software and hardware
                                                                                                     the satisfaction of search problem, distractions,                          images. However, there are much broader applica-
    development, of pattern recognition algorithms and lately deep
                                                                                                     fatigue, the varying subtlties of disease states and   tions beyond image analysis such as patient selection and examination
    learning, which are expected to allow healthcare providers to perform
                                                                                  normal, their prior training and experience, and the somewhat endless     scheduling, image acquisition and reconstruction, using image data
    their tasks with more reliability, accuracy, and to avoid critical errors,
                                                                                  non-image-interpretation tasks associated with a radiology practice.      for prognostic purposes, and combing image data with information
    known in medicine as sentinel events. While there is excitement about
                                                                                  The understanding of artificial intelligence (AI) on a radiologist’s      from electronic health records, laboratory and genetic data. Fur-
    robots and androids also performing human tasks, as physicians and
                                                                                  interpretation can be likened to considering the suggestions from a       thermore, in order for algorithms to be broadly accepted, there are
    healthcare providers, we cannot lose the human touch, as that is a
                                                                                  first-year resident to incorporating insights from a seasoned expert.     many scenarios where it is important for the clinician that results are
    critical component in improving the experience and probably outcome
                                                                                  Kundel’s eye gaze experiments which demonstrated the search               explainable. In addition, clinical deployment and workflow should be
    of patients when faced with medical illness. Currently deployed AI and
                                                                                  patterns of radiologists and laymen continue to be used today to          taken into consideration when designing the algorithm and bringing
    healthcare software often fails by distracting providers and decreases
                                                                                  understand the added influence of AI in the end user’s performance.       it to clinical practice. In my lecture I will focus on these aspects from
    human interaction time with patients. The current state of software
                                                                                  Multi-disciplinary perception research has evolved from understanding     a cardiovascular imaging perspective.
    also often fails in catching mistakes and may even cause mistakes.
                                                                                  human performance in the interpretation of medical images, to the
    We will discuss what is needed in order to truly improve the patient’s                                                                                  Biography: Dr. Tim Leiner is tenured Professor of Radiology and holds
                                                                                  understanding of computer-aided diagnosis (CAD), and to now the
    experience and outcomes, and which tasks would ideally be taken                                                                                         the Chair in Cardiovascular Imaging at Utrecht University Medical
                                                                                  understanding of AI -- either as an aid to radiologists as a second
    over by a future “AI”. Real life case examples will be used to make                                                                                     Center, Utrecht, The Netherlands. His research interests center around
                                                                                  reader, a concurrent reader, or a primary reader, or as a complete
    the points in this lecture.                                                                                                                             the development and implementation of new MR and CT techniques
                                                                                  replacement. This lecture will take the audience through history to
                                                                                                                                                            with a focus on cardiovascular imaging and machine learning. Dr.
    Biography: Jonathan Wiener, MD is the Director of Neuroradiology              appreciate the role and necessity of perception (and its associated
                                                                                                                                                            Leiner is Associate Editor of the Journal of Magnetic Resonance
    and MRI at Boca Radiology Group and Boca Raton Regional Hospital              metrics of performance) in the development, validation, and ultimate
                                                                                                                                                            Imaging (JMRI), the Journal of Cardiovascular Magnetic Resonance
    since 1989. Dr. Wiener is currently an Associate Clinical Professor at        future implementation of AI in the clinical radiology workflow.
                                                                                                                                                            (JCMR), and Radiology – Cardiothoracic. He is the author of over 300
    Florida Atlantic University, teaching medical students and residents.
                                                                                  Biography: Maryellen Giger, Ph.D. is the A.N. Pritzker Professor of       original papers, review articles and book chapters as well as editor of
    He completed a degree in chemistry and obtained his medical degree
                                                                                  Radiology / Medical Physics at the University of Chicago. She has been    several electronic radiology textbooks. He is currently Vice-President
    at the State University of New York Downstate Medical Center. He then
                                                                                  working, for multiple decades, on computer-aided diagnosis /machine       of the ISMRM.
    trained in internal medicine at the Albert Einstein Montefiore Medical
                                                                                  learning/deep learning in medical imaging and cancer diagnosis /
    Center. Dr. Wiener completed his Residency and Neuroradiology
                                                                                  management. Her AI research in breast cancer for risk assessment,
    Fellowship at the Mallinckrodt Institute of Radiology, Washington
                                                                                  diagnosis, prognosis, and therapeutic response has yielded various
    University, St. Louis, MO. He worked as an ER physician at the St.
                                                                                  translated components, and she is using these “virtual biopsies” in
    Louis County Regional Hospital. His career has included 35 years of
                                                                                  imaging-genomics association studies. Giger is a former president of
    collaborations with the medical industry in software and hardware
                                                                                  AAPM and of SPIE; and is the Editor-in-Chief of the Journal of Medical
    development, his publications include a book on the physics of MRI
                                                                                  Imaging. She is a member of the NAE; Fellow of AAPM, AIMBE, SPIE,
    and a number of peer reviewed articles on software and its role in
                                                                                  SBMR, IEEE, IAMBE; and was cofounder, equity holder, and scientific
    clinical care.
                                                                                  advisor of Quantitative Insights [now Qlarity Imaging], which produces
                                                                                  QuantX, the first FDA-cleared, machine-learning driven CADx system.

8                                                                    SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
DIGITAL PATHOLOGY
Conference Wednesday Keynote Presentation
Wednesday 11320 19 February 2020 • 1:20 PM - 2:20 PM
Location: Salon A

Petascale computational pathology
for precision medicine
                   Nasir Rajpoot
                   Univ. of Warwick (United Kingdom)
                    Abstract: Modern day slide scanners are capable
                    of generating large microscopic resolution images
                    of conventional tissue slides, spurring a revolution
                    in the practice of cellular pathology as a discipline.
                    This development comes at a time when computing
                    capacity and machine learning technologies are
peaking, offering a remarkable opportunity to reveal complex cellular
patterns in a data-driven manner. With an increasing number of NHS
pathology labs being digitised in the UK, there is an explosion in the
amount of pathology image data with linked clinical outcomes. This
data is a potential goldmine of invaluable information, ripe for deep
mining of novel digital histological biomarkers of the ‘state of play’ of
complex diseases such as cancer. How can we facilitate the discovery
of digital histology biomarkers to further our understanding of cancer,
stratify patients into different risk groups and predict the progression
and survival of cancer?
Biography: Nasir Rajpoot is Professor of Computational Pathology at
the Computer Science department of the University of Warwick, where
he started his academic career as a Lecturer (Assistant Professor) in
2001. He also holds an Honorary Scientist position at the Department
of Pathology, University Hospitals Coventry & Warwickshire NHS
Trust since 2016.
                                                                                M EDICAL IM AGING FOR DETECTION,
Prof Rajpoot is the founding Head of Tissue Image Analytics laboratory       DIAGNOSTICS, AND THERAPY OF DISEASE
(TIA lab) at Warwick since 2012. In Autumn 2017, he was awarded the
Wolfson Fellowship by the UK Royal Society and the Turing Fellowship                       spie.org/jmi
by the Alan Turing Institute, the UK’s national institute for data science
and artificial intelligence.
Current focus of research in Prof Rajpoot’s lab is on developing algo-
rithms for the analysis of digitised pathology images, with applications
to computer-assisted grading of cancer and image-based markers
for prediction of cancer progression and survival. He has been active
in the digital pathology community for almost a decade now, having
co-chaired several meetings in the histology image analysis (HIMA)
series since 2008 and served as a founding PC member of the SPIE
Digital Pathology meeting since 2012.
Prof Rajpoot served as the President of the European Congress on
Digital Pathology (ECDP), which was held at Warwick in April 2019.
Since Jan 2019, he acts as Co-Director of the £15m PathLAKE national
centre of excellence on AI in pathology, leading the computational
arm of the centre.

                                                                                                                   9
Special Events • Technical Events                                                                                                                                     • FREE •
                                                                                                                                                                        OPEN TO ALL
                                                                                                                                                                        CONFERENCE
                                                                                                                                                                         ATTENDEES
                                          Join your peers and colleagues in group discussions around focused technical topics,
                                          various workshops, live demos, and at the interactive poster sessions.

                                          Sunday/Monday Poster Viewing                                            TECHNICAL WORKSHOP
                                          Monday 17 February 2020 • 5:30 PM - 7:00 PM                             X-ray Source Technologies:
                                          Location: Salon D/E
                                                                                                                  Fundamental Principles, Technological
                                            Poster authors are required to:                                       Advances, and Clinical Needs
                                             • Display the poster early on the first day of your session.         Sunday 16 February 2020 • 5:45 PM - 7:45 PM
                                                                                                                  Location: Salon A
                                             • Attend the Poster Session to answer questions.
                                                                                                                  WK 1 TECHNICAL WORKSHOP: PHYSICS OF MEDICAL
                                             See Poster Presentation Guidelines for additional information.       IMAGING (CONFERENCE 11312)
                                          Poster presentations from the following conferences will be included:   The x-ray source is one of the key components in modern x-ray and
                                          Physics of Medical Imaging; Computer-Aided Diagnosis; Image-Guided      Computed Tomography (CT) imaging. X-ray beam characteristics have
                                          Procedures, Robotic Interventions, and Modeling; Imaging Informatics    a profound impact on conventional x-ray and CT image quality. For this
                                          for Healthcare, Research, and Applications; and Ultrasonic Imaging      workshop, expert speakers were invited to discuss the fundamentals
                                          and Tomography conferences will be included.                            of conventional x-ray tubes, the physical principles that drive source
                                                                                                                  technological innovations, and finally the challenges and opportuni-
                                          Author Set-Up Time: Sunday after 12:00 PM (noon)
                                                                                                                  ties of new x-ray source technology in current and future x-ray based
                                          In order to be fully considered for a Poster Award, it is recommended   medical imaging. Several blue sky short talks will introduce potentially
                                          to have your poster up as soon as possible.                             impactful source technologies.
                                          Posters should remain on display until the end of the Poster Session    SPEAKERS:
                                          on Monday.                                                              Rolf Behling, Phillips Medizin Systeme GmbH (Germany) -
                                          Poster Session and Reception: Monday from 5:30 to 7:00 PM               “Fundamentals of Conventional X-ray Tube Technologies”
                                          NOTE: Extended poster viewing until 9:00 PM on Sunday.                  Paul Schwoebel, Univ. of New Mexico and SRI International (USA)
                                          Poster award winners will be recognized and certificates distributed    - “Fundamental Physics Principles that Drive New X-ray Source
                                          in the conference meeting rooms. Check conference schedules for         Developments”
                                          times and locations. Ribbons will identify winning posters during the   Norbert Pelc, Stanford Univ. (USA) - “Challenges and Opportunities
                                          Poster Sessions.                                                        of X-ray Source Technologies in Present and Future Applications”
                                                                                                                  Blue Sky Talks To Be Announced

10                         SPIE Medical Imaging 2020 • spie.org/mi20program • #SPIEMedicalImaging
Special Events • Technical Events
TECHNICAL WORKSHOP                                                        TECHNICAL WORKSHOP
                                                                                                                                               TECHNICAL WORKSHOP
Live Demonstrations                                                       Translation of Deep Learning
Sunday 16 February 2020 • 5:45 PM - 7:45 PM                               Technology to the Clinic                                             Simulated Tumor Board: Brain and
Location: Salon D/E                                                       Tuesday 18 February 2020 • 5:00 PM - 7:00 PM                         Breast
WK 4 COMPUTER-AIDED DIAGNOSIS (CONFERENCE 11314)                          Location: Salon C                                                    Tuesday 18 February 2020 • 5:00 PM - 7:00 PM
                                                                                                                                               Location: Salon B
WORKSHOP CHAIRS:                                                          WK 2 TECHNICAL WORKSHOP: IMAGE PROCESSING
Dr. Lubomir Hadjiiski, Univ. of Michigan Health System (USA)              (CONFERENCE 11313)                                                   WK 3 TECHNICAL WORKSHOP: COMPUTER-AIDED
Dr. Karen Drukker, Univ. of Chicago (USA)                                 Medical AI market is expected to break to 2 billion USD revenue      DIAGNOSIS (CONFERENCE 11314) AND DIGITAL PATHOLOGY
                                                                          within 5 years. Even though promising we still need to overcome      (CONFERENCE 11320)
CALL FOR PARTICIPATION                                                    several barriers including technological robustness, clinical        This workshop will present two example clinical cases, one breast
The goal of this workshop is to provide a forum for systems and           validation, regulatory compliance, market acceptance and financial   cancer case and one brain cancer case. A multi-disciplinary team will
algorithms developers to show off their creations. The intent is for      risks. In a number of presentations we focus on the barriers         discuss the case, the imaging information, pathology, and treatment
the audience to be inspired to conduct derivative research, for the       and how to overcome these seen from start-up, regulators, and        options. The workshop will mimic the format of a standard clinical
demonstrators to receive feedback and find new collaborators, and         commercial perspectives.                                             tumor board process with time for Q&A at the end.
for all to learn about the rapidly evolving field of medical imaging.                                                                          MODERATOR:
                                                                          PROGRAM:
The Live Demonstration Workshop encourages participation from all of                                                                           Kristy Brock, PhD, DABR, FAAPM
                                                                          5:00 PM: Introduction by Hayit Greenspan, Tel Aviv Univ. (Israel)    Professor, Department of Imaging Physics and Department of
the conferences that comprise the SPIE Medical Imaging symposium.                  and Mads Nielsen, Univ. of Copenhagen (Denmark)
We encourage the CAD, Digital Pathology, Image Processing, Imaging                                                                             Radiation Physics, Univ. of Texas MD Anderson Cancer Center (USA)
                                                                          5:10 PM: Nico Karssemeijer - The start-up perspective
Informatics, Image Perception, Physics, and all other conferences to                                                                           BREAST PANEL SPEAKERS:
                                                                          5:35 PM: Stephen Aylward - The technology perspective
participate.                                                                                                                                   Simona Shaitelman, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                          6:00 PM: Weijie Chen - The regulatory perspective                    Radiation Oncology (USA)
This workshop features interactive demonstrations that are comple-        6:25 PM: Ole Graumann - The radiologist perspective
mentary to the topics of SPIE Medical Imaging. Workshop demon-                                                                                 Isabelle Bedrosian, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                          6:50 PM: Discussion of learnings and Q & A                           Surgery (USA)
strations include samples, systems, and software demonstrations that
depict the implementation, operation, and utility of cutting-edge as                                                                           Jennifer Litton, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                          SPEAKERS:
well as mature research. Having an accepted SPIE Medical Imaging                                                                               Medical Oncology (USA)
                                                                          Nico Karssemeijer, Radboud University Medical Ctr. (Netherlands)     Wei Yang, Univ. of Texas MD Anderson Cancer Ctr.,
paper is not required for giving a Live Demonstration; however, authors
                                                                          and Screenpoint (USA)                                                Diagnostic Radiology (USA)
of SPIE Medical Imaging papers are encouraged to submit demonstra-
tions that are complementary to their oral and poster presentations.      Stephen Aylward, Kitware, Inc. (USA) -                               Alejandro Contreras, Univ. of Texas MD Anderson Cancer Ctr.,
The session will include a Certificate of Merit Award presented to one    “Delivering Clinical Deep Learning Algorithms”                       Pathology (USA)
demonstration considered to be of exceptional interest. We invite all     Weijie Chen, U.S. Food and Drug Administration (USA) -
workshop visitors to vote for three of their favorite demonstrations,                                                                          BRAIN PANEL SPEAKERS:
                                                                          “Assessment of AI/ML based devices in medical imaging
with the final winner chosen from the top scorers by a group of ap-                                                                            Caroline Chung, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                          applications”
pointed judges.                                                                                                                                Radiation Oncology (USA)
                                                                          Ole Graumann, Odense Univ. Hospital (Denmark) -                      Jeff Weinberg, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                          “What deep learning technology does the clinic need?”                Surgery (USA)
                                                                                                                                               Melissa Chen, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                                                                                               Diagnostic Radiology (USA)
                                                                                                                                               Jason Huse, Univ. of Texas MD Anderson Cancer Ctr.,
                                                                                                                                               Pathology (USA)

                                                                                                                                                                                                                       11
Special Events • Technical Events
     TECHNICAL WORKSHOP                                                         Tuesday/Wednesday Poster Viewing
     Task-driven AI: Taking into Account                                        Wednesday 19 February 2020 • 5:30 PM - 7:00 PM
                                                                                Location: Salon D/E
     the User’s Perspective
     Tuesday 18 February 2020 • 5:00 PM - 7:00 PM                               Two poster sessions are scheduled. See Poster Presentation Guidelines
     Location: Salon A                                                          for additional information.
     WK 5: TECHNICAL WORKSHOP: IMAGE PERCEPTION,                                  Poster authors are required to:
     OBSERVER PERFORMANCE, AND TECHNOLOGY
                                                                                   • Display the poster early on the first day of your session
     ASSESSMENT CONFERENCE (CONFERENCE 11316)                                                                                                           EQUITY
     Machine learning and artificial intelligence techniques are exponen-          • Attend the Poster Session to answer questions.
                                                                                                                                                        Is access to opportunities,
     tially being developed and applied to a wide variety of scenarios             See Poster Presentation Guidelines for additional information.       fair treatment, and
     in medical imaging ranging from image segmentation and analysis                                                                                    advancement for all
     to analyzing radiologists’ reports to managing clinical workflow.          Poster presentations from the following conferences will be included:   people; it’s about
     Although we are slowing seeing these applications integrated into          Image Processing; Image Perception, Observer Performance, and           eliminating barriers that
     clinical workflow, much of the development work is still in the research   Technology Assessment; Biomedical Applications in Molecular, Struc-     prevent full participation.
     stages. In order to bridge the gap between research and clinical inte-     tural, and Functional Imaging; and Digital Pathology.
     gration and implementation, a greater emphasis needs to be placed on       Author Set-Up Time: Tuesday after 9:30 AM
     understanding the impact of the output of these machine learning and       In order to be fully considered for a Poster Award, it is recommended
                                                                                                                                                        DIVERSITY
     AI schemes on the human decision-maker. This workshop will present         to have your poster up as soon as possible.                             Includes all the ways in
     a variety of perspectives on the role of AI and machine learning in                                                                                which people differ—
                                                                                Posters should remain on display until the end of the Poster Session
     medical imaging from the perspective of the users.                                                                                                 identity markers such as
                                                                                on Wednesday.
                                                                                                                                                        race, ethnicity, gender,
     MODERATORS:
                                                                                Poster Session and Reception: Wednesday from 5:30 to 7:00 PM            ability, sexual orientation,
     Yan Chen, Univ. of Nottingham (United Kingdom)                                                                                                     and more.
                                                                                NOTE: Extended poster viewing until 9:00 PM on Tuesday.
     Elizabeth A. Krupinski, Emory Univ. (USA)
                                                                                Poster award winners will be recognized and certificates distributed
     PANELISTS:                                                                 in the conference meeting rooms. Check conference schedules for         INCLUSION
     Sian Taylor-Phillips, Univ. of Warwick (United Kingdom)                    times and locations. Ribbons will identify winning posters during the   Goes beyond diversity:
     Francine Jacobson, Brigham and Women’s Hospital (USA)                      Poster Sessions.                                                        it’s the act of creating
     Elizabeth A. Krupinski, Emory Univ. (USA)                                                                                                          an environment where
                                                                                                                                                        everyone feels welcomed,
                                                                                                                                                        respected, supported,
                                                                                                                                                        and valued.

                                                                                                                                                        spie.org/inclusion

12                                                                 SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
• NOTE •
Special Events • Social and Networking Events                                                                                                                                                   SOME EVENTS
                                                                                                                                                                                            REQUIRE TICKETS AND
                                                                                                                                                                                               REGISTRATION.
Join your colleagues at various events, including the Student Dessert                                                                                                                      SEE INDIVIDUAL EVENTS
with the Experts, and Women’s Networking Lunch—events not to be missed!                                                                                                                         FOR DETAILS.

Equity, Diversity, and Inclusion                                         Women’s Networking Luncheon                                             Dessert with the Experts -
Presentation and Reception                                               Monday 17 February 2020 • 12:10 PM - 1:20 PM                            A Student Networking Event
                                                                         Location: Kingwood
Sunday 16 February 2020 • 5:30 PM - 7:00 PM                                                                                                      Wednesday 19 February 2020 • 6:30 PM - 7:30 PM
Location: Salon F                                                        Sign up at registration before Monday morning coffee                    Location: Kingwood
                                                                         break.
Open to those with a paid registration badge.                                                                                                    Open to student conference attendees.
                                                                         Join other women in the field for informal discussions and networking   First come, first served.
Join us for a thought-provoking presentation and stay after to discuss
                                                                         during the scheduled lunch on Monday.                                   Enjoy a tasty dessert and casual atmosphere while networking with
topics with your colleagues during the reception.
                                                                                                                                                 some of the best and brightest minds in medical imaging. Exchange
                                                                                                                                                 ideas, share experiences, gain career advice, and make valuable
                                                                                                                                                 contacts at this complimentary student event.

                              THIS PDF PROGRAM IS CURRENT AS OF 20 JANUARY 2020. Find complete, up-to-date information and create your personalized schedule at spie.org/mi                                          13
Special Events • Award Events
      THE 2020 STUDENT PAPER AWARDS
                                                                         2020 Poster Award Information                                             Robert F. Wagner All-Conference Best
      SPIE annually hosts the Best Student Poster presentation
                                                                         Monday 17 February 2020 • 8:00 AM - 8:30 AM                               Student Paper Award
                                                                         POSTER AWARDS IN CONFERENCE ROOMS                                         Monday 17 February 2020 • 4:15 PM - 4:30 PM
      contests, with certificates awarded. Some conferences host
                                                                                                                                                   Location: Salon F
      Best Student Paper Awards with cash prizes supported by the        Check the conference schedule for exact times.
      generosity of our sponsors. Entrants are judged by a commit-                                                                                 The Robert F. Wagner All Conference Best Student Paper Award
      tee of SPIE volunteers and winners are announced onsite. We
                                                                         RFW AWARD FINALISTS:                                                      (established 2014) is an acknowledgement of his many important
                                                                         RFW Award finalists will be recognized and certificates distributed in    contributions to the Medical Imaging meeting and his many important
      thank our many award sponsors.
                                                                         the conference meeting rooms. See conference schedules for times          advances in the field of medical imaging.
                                                                         and locations.
                                                                                                                                                   CO-SPONSORED BY:

                                                                         POSTER AWARDS:
                                                                         Each conference will recognize selected poster presentations of ex-
                                                                         ceptional quality at either the Cum Laude or Honorable Mention level.
                                                                         Winners will be chosen by members of conference review committees.
                                                                         The winning posters will be identified during the receptions with award   Contributions by the Medical Imaging Community
                                                                         ribbons. Winners will be recognized and certificates distributed in
                                                                         the conference meeting rooms. See conference schedules for times          Robert F. Wagner Award Finalists will be recognized with certificates
                                                                         and locations.                                                            in their respective conference meeting rooms during the Awards
                                                                                                                                                   Sessions. See conference schedules for times and locations.
                                                                         In addition, Cum Laude poster award recipients will be recognized
                                                                         in the Proceedings of SPIE volumes and the following year’s Call for
                                                                         Papers.
                                                                                                                                                   Image-Guided Procedures, Robotic
                                                                         RECOGNITION LEVELS:                                                       Interventions, and Modeling Awards
                                                                         Each conference will recognize 1 selected poster at the Cum Laude         Tuesday 18 February 2020 • 12:10 PM - 12:15 PM
                                                                         level and 1 selected poster at the Honorable Mention level for the        Location: Hunter’s Creek
                                                                         quality of work presented as well as the presentation.
                                                                                                                                                   Image-Guided Procedures, Robotic Interventions, and Modeling
                                                                         BASIS FOR SELECTION:                                                      Young Scientist, Student Paper, and Poster Awards (Conference
                                                                         Work should be of a standard of excellence as judged by the quality       11315)
                                                                         and quantity of results presented. It should include results that are
                                                                                                                                                   YOUNG SCIENTIST AWARD
                                                                         both significant and new to the field of study. Conclusions should be
                                                                         well supported by the results, and relevant references should be cited.   This award is specific to papers in the Image-Guided Procedures,
                                                                                                                                                   Robotic Interventions, and Modeling conference 11315.
                                                                         Presentation should be well organized, clear, and concise. It should
                                                                         be self-contained, giving adequate background, concise results, and       The Young Scientist Award is a prize awarded to the first authors of
                                                                         relevant references. Graphic design will be considered only to the        high quality papers within the Image-Guided Procedures, Robotic
                                                                         extent that it contributes to the clarity of presentation.                Interventions, and Modeling conference.
                                                                         A conference may give preference to first authors who are students        SPONSORED BY:
                                                                         or who are within five years of their terminal degrees.

14                                                            SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
Image-Guided Procedures Student                                                   Physics of Medical Imaging Student                                                          Image Processing Student Paper and
Paper Award                                                                       Paper and Poster Awards                                                                     Poster Awards
                                                                                  Wednesday 19 February 2020 • 9:40 AM - 9:45 AM                                              Thursday 20 February 2020 • 12:10 PM - 12:15 PM
This award is specific to papers in the Image-Guided Procedures,
                                                                                  Location: Salon A                                                                           Location: Salon C
Robotic Interventions, and Modeling Conference 11315.
                                                                                  Physics of Medical Imaging Student Paper Award (Conference 11312)                           Image Processing Student Paper Award (Conference 11313)
The Image-guided Procedures, Robotic Interventions and Modeling
conference is featuring a new paper award specifically dedicated to               This award is specific to papers in the Physics of Medical Imaging                          This award is specific to papers in the Image Processing conference
recognize outstanding papers in the area of surgical robotics and                 conference 11312.                                                                           11313.
related topics.                                                                   The student paper award is a prize awarded to the first authors of                          The student paper award is a prize awarded to the first authors of high
SPONSORED BY:                                                                     high quality papers within the Physics of Medical Imaging conference.                       quality papers within the Image Processing conference.
                                                                                  SPONSORED BY:                                                                               SPONSORED BY:

The award winners for both awards will be recognized in the confer-
ence room on Tuesday morning before the lunch break.                                                                                                                          The award winners will be recognized in the conference room before
POSTER PRESENTATION AWARDS                                                                                                                                                    lunch on Thursday.
                                                                                  The award winners will be recognized in the conference room before
SPONSORED BY:                                                                                                                                                                 IMAGE PROCESSING POSTER PRESENTATION AWARD
                                                                                  the morning coffee break on Wednesday.
                                                                                                                                                                              SPONSORED BY:
                                                                                  PHYSICS OF MEDICAL IMAGING POSTER PRESENTATION AWARDS
                                                                                  SPONSORED BY:
The Image-Guided Procedures, Robotic Interventions, and Modeling
conference will offer cash prizes as part of the poster presentation
                                                                                                                                                                              The Image Processing conference will offer one cash prize as part of
awards. Poster presentations must be displayed early on the first
                                                                                                                                                                              the poster presentation awards. Poster presentations must be dis-
day of the Sunday/Monday poster session to enter the competition.                 The Physics of Medical Imaging conference will offer cash prizes as
                                                                                                                                                                              played early on the first day of the Tuesday/Wednesday poster session
The space will be available to display posters beginning at noon on               part of the poster presentation awards. Poster presentations must be
                                                                                                                                                                              to enter the competition. The space will be available to display posters
Sunday. Award announcements will take place in the conference room                displayed early on the first day of the Sunday/Monday poster session
                                                                                                                                                                              beginning at noon on Tuesday. Award announcements will take place
on Tuesday morning before the lunch break.                                        to enter the competition. The space will be available to display posters
                                                                                                                                                                              in the conference room before lunch on Thursday.
                                                                                  beginning at noon on Sunday. Award announcements will take place in
                                                                                  the conference room before the morning coffee break on Wednesday.

                                                                                         Poster session dates, locations, and times
                                      SESSION                      CONFERENCES                            SETUP                    LOCATION                   SESSION TIME                   TEARDOWN
                                                                                                     Sunday,
                                   Monday                    11312; 11314; 11315; 11318;             16 February               Texan Ballroom,              Monday,
                                                             11319                                                                                                                          7:00 PM
                                   17 February                                                       after 12:00 PM            4th Floor - Salon D          5:30 PM - 7:00 PM
                                                                                                     (noon)*

                                   Wednesday                                                         Tuesday,
                                                                                                     18 February               Texan Ballroom,              Wednesday,
                                                             11313; 11316; 11317; 11320                                                                                                     7:00 PM
                                   19 February                                                                                 4th Floor - Salon D          5:30 PM - 7:00 PM
                                                                                                     after 9:30 AM*
                                   *In order to be fully considered for a Poster Award, it is recommended to have your poster up as soon as possible. Posters should remain on display until the end of the
                                    Poster Session on either Monday or Wednesday.

                             THIS PDF PROGRAM IS CURRENT AS OF 20 JANUARY 2020. Find complete, up-to-date information and create your personalized schedule at spie.org/mi                                                                               15
Daily Events Schedule
                SATURDAY                                     SUNDAY                                    MONDAY                                      TUESDAY                                   WEDNESDAY                                  THURSDAY
                15 February                                16 February                                17 February                                 18 February                                29 February                                20 February
                                              Conference 11312: Physics of Medical Imaging, p. 32
                                              Chairs: Guang-Hong Chen, Univ. of Wisconsin-Madison (USA); Hilde Bosmans, Katholieke Univ. Leuven (Belgium)
                                                                                                               CONFERENCE 11313: Image Processing, p. 32
                                                                                                               Chairs: Ivana Išgum, Amsterdam UMC (Netherlands); Bennett A. Landman, Vanderbilt Univ. (USA)
     SC086 Fundamentals of Medical Image      Conference 11314: Computer-Aided Diagnosis, p. 32
     Processing and Analysis (Deserno)        Chairs: Horst K. Hahn, Fraunhofer MEVIS (Germany), Jacobs Univ. Bremen (Germany); Maciej A. Mazurowski, Duke Univ. (USA)
     8:30 AM - 5:30 PM, $565 / $660, p. 20

     SC1235 Introduction to Medical Image     Conference 11315: Image-Guided Procedures, Robotic Interventions, and Modeling, p. 32
     Analysis Using Convolutional Neural      Chairs: Baowei Fei, The Univ. of Texas at Dallas (USA), The Univ. of Texas Southwestern Medical Ctr. (USA);
     Networks (Wenzel, Weiler) 8:30 AM -      Cristian A. Linte, Rochester Institute of Technology (USA)
     5:30 PM, $595 / $690, p. 21
     SC1292 Technological Assessment of                                                                                                                                            Conference 11316: Image Perception, Observer Performance, and
     X-Ray Based Breast Imaging Systems
     Using Anthropomorphic Phantoms
                                                                                                                                                                                   Technology Assessment, p. 32
                                                                                                                                                                                   Chairs: Frank W. Samuelson, U.S. Food and Drug Administration (USA);
     (Glick, Bosmans, Badal)
     8:30 AM 12:30 PM, $325 / $380, p. 22                                                                                                                                          Sian Taylor-Phillips, The Univ. of Warwick (United Kingdom)

     SC1129 Photon Counting CT (Danielsson,   Conference 11318: Imaging Informatics for Healthcare,                                    Conference 11317: Biomedical Applications in Molecular, Structural, and
     Sjölin) 1:30 PM 5:30 PM, $325 / $380,    Research, and Applications, p. 33                                                        Functional Imaging, p. 33
     p. 20
                                              Chairs: Po-Hao Chen, Cleveland Clinic (USA); Thomas M. Deserno, Technische               Chairs: Barjor Gimi, Cooper Medical School, Rowan Univ. (USA); Andrzej Krol, SUNY Upstate Medical Univ. (USA)
                                              Univ. Braunschweig (Germany)
                                              Conference 11319: Ultrasonic Imaging and Tomography, p. 33                                                                           Conference 11320: Digital Pathology, p. 33
                                              Chairs: Brett C. Byram, Vanderbilt Univ. (USA); Nicole V. Ruiter, Karlsruher Institut für Technologie (Germany)                      Chairs: John E. Tomaszewski, Univ. at Buffalo (USA); Aaron D. Ward, The Univ. of
                                                                                                                                                                                   Western Ontario (Canada)
                                              SC1262 Adversarial Networks: From           KEYNOTE PRESENTATION:                        SC1295 From Analytic to Clinical            KEYNOTE PRESENTATION:                      Image Processing Student Paper and
                                              Architecture to Practical Training          Shining light into the machine learning      Validation: Moving AI/ML into Practice      Towards understanding perception in the    Poster Awards • Conf. 11313,
                                              (Wenzel, Weiler) 8:30 AM - 12:30 PM,        “black box”: the state of explainable AI •   (Hsu, Brown, Nishikawa, Krupinski)          latest era of AI in medical imaging        12:10 PM - 12:15 PM, p. 15
                                              $325 / $380, p. 22                          Conf. 11318, William Hsu,                    8:30 AM - 5:30 PM, $565 / $660, p. 23       Conf. 11316, Maryellen Giger,
                                                                                          8:00 - 8:40 AM, p. 8                                                                     8:00 - 9:00 AM, p. 8
                                              Sunday/Monday Poster Author Set-Up:         SC987 Spectral CT Imaging                    SC1239 Virtual Clinical Trials:             KEYNOTE PRESENTATION:
                                              Sunday after 12:00 PM (NOON), p. 10         (Schmidt, Grant) 8:30 AM - 12:30 PM,         An In-depth Tutorial (Maidment, Bakic,      Bringing machine learning to the clinic:
                                                                                          $325 / $380, p. 24                           Barufaldi) 8:30 AM - 12:30 PM,              opportunities and challenges
                                                                                                                                       $335 / $390, p. 22                          Conf. 11313, Tim Leiner,
                                                                                                                                                                                   10:10 - 11:10 AM, p. 8
                                              SC1296 High-Performance Computing           KEYNOTE PRESENTATION:                        Tuesday/Wednesday Poster Author             KEYNOTE PRESENTATION:
                                              for Medical Imaging on Graphics             Innovations and translation in molecular     Set-Up: Tuesday after 9:30 AM, p. 14        Petascale computational pathology for
                                              Processing Units (GPU) with CUDA            PET/MR and PET/CT • Conf. 11312,                                                         precision medicine • Conf. 11320,
                                              (Caucci) 1:30 PM - 5:30 PM,                 Georges El Fakhri, 10:10 - 10:50 AM, p. 8                                                Nasir Rajpoot, 1:20 - 2:20 PM, p. 9
                                              $325 / $380, p. 24
                                              KEYNOTE PRESENTATION:                       Women’s Networking Luncheon,                 KEYNOTE PRESENTATION:
                                              Cybersecurity in healthcare: is our         12:10 - 1:20 PM, p. 13                       Label-free molecular imaging with spins:
                                              patients’ health now at risk? • Conf.                                                    a path to high resolution through learned
                                              11318, Jim Whitfill, 3:30 - 4:30 PM, p. 8                                                subspaces • Conf. 11317,
                                                                                                                                       Zhi-Pei Liang, 10:10 - 11:10 AM, p. 7

16                                                                           SPIE Medical Imaging 2020 • spie.org/mi • #SPIEMedicalImaging
You can also read