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GRANADA CANDIDATURE FOR 19TH ICNCT
19th International Congress on Neutron Capture Therapy
September/October 2020
Candidature of Granada, Spain
This document contains a proposal to the International Society for
Neutron Capture Therapy for organizing the 19th International Congress of
Neutron Capture Therapy in Granada, Spain, in September or October of
2020.
Local Organizing Committee
• Ignacio Porras, Professor of Physics, University of Granada, member
of ISNCT since 2008 and member of the Board of Councillors.
• Javier Praena, PhD in Physics, University of Granada, member of
ISNCT since 2012.
• Fernando Arias de Saavedra, Professor of Physics, University of
Granada, member of ISNCT since 2014.
• Manuel P. Sabariego, PhD in Physics, University of Granada,
member of ISNCT since 2014.
• Marta Sabaté-Gilarte, PhD in Physics, CERN and University of
Seville, member of ISNCT since 2014.
• Rosario Núñez, PhD in Chemistry, Institute of Material Science of
Barcelona.
• Clara Viñas, PhD in Chemistry, Institute of Material Science of
Barcelona.
• José Expósito, MD, Head of Oncology, Hospital Universitario de
Granada.
• Juan Luis Osorio, Radiophysicist, Hospital Universitario de Granada.
• Maria del Carmen Ruiz-Ruiz, PhD in Biochemistry, University of
Granada.
• Maria José Ruiz-Magaña, PhD in Biochemistry, University of
Granada
• María Pedrosa, PhD student, Institute Laue-Langevin and University
of Granada
GRANADA CANDIDATURE FOR 19TH ICNCT
Foreword of I. Porras
I had the honor and the pleasure of being the meeting organizer of the 7th
International Meeting of Young Researchers in Boron Neutron Capture Therapy which
took place in Granada, Spain, from 22nd to 26th of September 2013. When I presented
the proposal to the ISNCT in 2011, the great response of all the community filled me
with joy. This was an example of the great feelings that I have contrasted in all the
ISNCT Congresses that I have attended. There is an interdisciplinary atmosphere of
collaboration, communication and mutual encouragement that is not common in other
fields of science. I am absolutely grateful to all members of this scientific community.
We are taking a step ahead and proposing to the ISNCT holding one of these
Congresses of the Society. We will make all our efforts, if this candidacy is approved, of
maintain all the values of these meetings.
Boron Neutron Capture Therapy (BNCT) is an experimental radiotherapy technique
continuously benefiting from active research throughout the world. It is based on
sound physical principles: the cell killing effect is produced by heavy charged ions
(alpha particle and a recoil nucleus), the products of a nuclear reaction which happens
inside the body by means of a low energy neutron when colliding with an specific
nucleus, which in all clinical applications is Boron-10. Then, when the two non-toxic
different components of the treatment (neutron field and B-10 tumor-specific
compound) meets, a huge amount of energy is delivered locally, by means of a very
short range radiation of a high biological effectiveness, and sparing healthy tissues.
The results from the clinical trials performed worldwide are very promising: BNCT is a
safe procedure (very small adverse effects), even for patients for which conventional
radiotherapy is not possible; an enlargement of the mean survival time is found for
very malignant diseases such as Glioblastoma Multiforme; a large percent of recurrent
malignant head and neck cancer patients (for which no other treatment was possible)
have shown complete tumor remission after a treatment of normally one session, and
it is an interesting option for other cancers of very bad prognosis. These latest results
have motivated a renewed interest from the authorities, an example of that is that the
Nuclear Physics European Collaboration Committee (NuPECC), an Expert Committee of
the European Science Foundation has devoted a chapter in the recent report of 2014
“Nuclear Physics for Medicine”, aimed for future science policies.
In order to become a well-established alternative to other cancer therapies, is it
important the progress in some research problems which will optimize treatments, the
construction of new facilities and the outreach of this promising therapy. BNCT is
facing a renovation that may increase its presence in clinical treatments in the
forthcoming years. This, and recent advances from research may lead to a new era in
BNCT.
GRANADA CANDIDATURE FOR 19TH ICNCT Our Spanish group is formed by physicists from the Universidad de Granada, chemists from the Institute of Material Sciences of Barcelona (ICMAB), biologists from the Center for Biomedical Research (CIBM) of the University of Granada, and medical doctors from the Granada University Hospital at the Technological Health Park (PTS) of Granada. In the latest years we have obtain a strong support from National and Regional governmental agencies and foundations, in particular we have obtained specific grants for BNCT research from the Junta de Andalucia (regional government) from 2013 to 2017, with a budget 275632 EUR, from the Spanish Ministry of Economy (2016 to 2019) with 41503 EUR, from the Spanish ACS Foundation (total 35000 EUR), the Campus for International Excellence BioTic of the University of Granada (20000 EUR in 2012, and 24000 EUR in 2014), and the most recent grant, of 143000 for the period 2016-2019 from the Spanish Association Against Cancer (AECC), a very prestigious foundation in Spain from particular donors. This grant comes from a very competitive process and has a strong relevance in Spain. The AECC grants will be formally given by the Queen of Spain in a formal institutional act that will place in September 22nd. Our main focus is the research in improvements of BNCT delivery, including the obtention of nuclear and radiobiology data for an accurate dose determination for treatment planning. For this purpose we have recently established collaborations with three very relevant nuclear facilities in Europe: the neutron time of flight collaboration at CERN, of which we are partners since 2015 for neutron cross sections measurements of relevance for BNCT, the Institute Laue-Langevin of Grenoble, France, for which we have recently signed a 3-year agreement for a research project of neutron radiobiology measurements for BNCT, the JRC-IRMM in Geel, Belgium, and the National Accelerator Center of Seville, Spain. The interest of these institutions on BNCT research can be a boost for the possible future BNCT network in Europe which is pursued by the important and active European groups which belongs to the ISNCT, and which collaborate also with those outside Europe. The celebration of the ICNCT conference will be of great help for this mission. We understand and share the feeling of importance and strong tradition of the biennial meetings of the ICNCT since the first one hold in Cambridge (USA). A rotation of continents gives a chance to Spain to host the 2020 conference. It would be a great honor to be part of the following list:
GRANADA CANDIDATURE FOR 19TH ICNCT 1st Cambridge, USA Brownell/Fairchild 1983 12-14 October 2nd Tokyo, Japan Hiroshi Hatanaka 1985 18-20 October 3rd Bremen, Germany Detlef Gabel 1988 31 May-3 June 4th Sydney, Australia Barry J. Allen 1990 4-7 December 5th Columbus, USA Albert J. Soloway 1992 14-17 September 6th Kobe, Japan Yutaka Mishima 1994 31 October- 4 November 7th Zurich, Switzerland Borje Larsson 1996 4-7 September 8th La Jolla, USA Frederick Hawthorne 1998 13-18 September 9th Osaka, Japan Keiji Kanda 2000 2-6 October 10th Essen, Germany Wolfgang Sauerwein 2002 8-13 September 11th Boston, USA Robert Zamenhof 2004 11-15 October 12th Takamatsu, Japan Yoshinobu Nakagawa 2006 9-13 October 13th Florence, Italy Aris Zonta 2008 2-7 November 14th Buenos Aires, Argentina Sara J. Liberman 2010 25-29 October 15th Tsukuba, Japan Akira Matsumura 2012 10-14 September 16th Helsinki, Finland Leena Kankaanranta 2014 14-19 June 17th Columbia, USA Satish Jalisatgi 2016 2-7 October 18th Taipei, ROC Fong-In Chou 2018 It would be exciting for us to organize, during five days, presentations of results from different fields in this interdisciplinary research, from engineering and physics to chemistry and pharmacology, and biology and clinical medicine. I hope this exchange of ideas will improve the common knowledge in the field and the rise of new collaborations. Ignacio Porras Department of Atomic, Molecular and Nuclear Physics Director of Department University of Granada, Spain.
GRANADA CANDIDATURE FOR 19TH ICNCT
Organizing Institution: University of Granada
Founded almost five hundred years ago, in 1531, during the reign of Charles V, the
Universidad de Granada has grown in close symbiosis with society and has become a
benchmark in terms of both the quality of its teaching and research and, with a
particular emphasis, its cooperation and development activities.
The various Campuses (Aynadamar, Cartuja, Fuentenueva and Centro), which
are spread all over the city, combined with the historical and heritage buildings in
some of the most unique neighbourhoods of Granada, re-energize the University, and
give the city a characteristic student atmosphere.
Our institution combines the wealth of experience that comes with its lengthy
tradition with the dynamism and youth of almost 60,000 undergraduates; the number
of students rises to 80,000 when postgraduates and students studying additional
courses are taken into account. The Universidad de Granada welcomes more students
from international mobility than any other Spanish university.
Our University is a reference in the health sciences. It hosts the Technological
Health Park (PTS). PTS is the first park specialized in health care in Spain and one of
very few throughout the world. It integrates teaching, research, patient care and
business development for Health and Biomedicine. PTS Granada covers an area of
625,000 m², housing all the infrastructures and facilities devoted to its four main uses:
teaching (98,000 m²), health care (120,000 m²), and research and business
development (170,000 m²). In the teaching area, the University of Granada plans to
invest nearly 200 million euros in the near future. This area is home of the shared
facilities of the Central Library, the Main Hall and the General Services Building, as well
as the faculties of Medicine, Dentistry, Pharmacy and Health Sciences. Teaching and
health care will be reinforced with the new University Hospital, a modern building with
an area of 110,000 m2, which is set to become a center of reference thanks to its high-
tech equipment, excellent healthcare services and efficient management processes.
GRANADA CANDIDATURE FOR 19TH ICNCT
The city
The Alhambra
Granada (pop. 250,000) is the capital of the province with the same name, situated in
the eastern part of the region of Andalusia. Geographical and scenic diversity
characterizes the land. There is the coastal area with its warm climate; the extensive,
fertile Genil plain; and the mountainous regions with a colder climate, where we find
the 3,481 meter Mulhacén, the biggest peak on the peninsula of Spain.
The city of Granada is located at the foot of the Sierra Nevada mountains at the
confluences of the Darro and Genil rivers. Its unique history has bestowed it with an
artistic grandeur embracing Moorish palaces and Christian Renaissance treasures. As
the last Moorish capital on the Iberian peninsula, it also holds great symbolic value.
The city of Granada has been shaped by the hills, where the old districts in the
Albaycín and the Alhambra were founded, brimming with steep, narrow streets,
beautiful nooks and crannies, and marvelous landscapes. The new part of the city is
situated on the plain, crisscrossed by the large arteries of Gran Vía de Colón and Calle
de los Reyes Católicos, and where the busy streets around the Cathedral are found.
GRANADA CANDIDATURE FOR 19TH ICNCT
The Moors crossed the strait of Gibraltar in 711 and settled in what was then a
small Visigoth town perched atop the Alhambra hill. Here they settled, erected walls
and laid the foundation for the prosperous civilization that would follow. It was in the
9th century when Granada rose to importance after the fall of the Caliphate of
Córdoba. Its splendor was reached in 1238, when Mohammed ben Nasar founded the
Nasrid dynasty, and the kingdom of Granada stretched from Gibraltar to Murcia. This
dynasty bore twenty kings until King Boabdil was forced to surrender Granada to the
Catholic monarchs, King Ferdinand and Queen Isabella, in 1492. During three
centuries, a magnificent and rich Islamic culture flourished, leaving Granada with
architectural marvels of the caliber of the Alhambra, declared a World Heritage Site,
along with the Generalife and the Albaycín.
Granada -a safe modern city- is also located in a privileged spot, halfway
between the sea and the mountains: 40 minutes from the Mediterranean coast's sub-
tropical climate and 30 minutes from the ski resort of Sierra Nevada.
Granada seduces you… Its fame as a cultural city, with its monuments, its
history and its university, not to mention its charm and its numerous cultural and
recreational activities, makes Granada a great city to explore and a great tourist
destination. The city of Granada offers you many cultural possibilities, including a
whole range of festivals: flamenco, jazz, tango, theatre, magic, music, dance, comics,
film, poetry…
Spanish food is internationally recognized for its quality and variety and
Granada is known for its "tapas". Besides, Granada is considered one of the cheapest
cities in Spain and Europe.
Weather
Temperature in Granada (ºC)
6.7 8.5 11.0 12.8 16.8 21.4 24.8 24.5 20.9 15.5 10.7 7.6
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Granada has short cold winters and is very hot in July and
August, it is not an uncomfortable heat because of the low
humidity. May, September and October are the mildest months
GRANADA CANDIDATURE FOR 19TH ICNCT
Rainfall in Granada (mm)
41 38 30 38 28 17 4 3 16 42 48 53
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
The rainfall in Granada is fairly low but occasionally every few
years there can be long wet spells which can last two or 3
weeks.
Number of cloudless days in Granada
10 7 7 5 6 13 22 19 11 8 8 8
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Good weather is the norm in Granada. Andalucia has more
sunshine than anywhere in Europe.
Number of rainy days in Granada
6 6 5 7 4 2 0 1 2 5 6 7
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
The chart show the amount of days when there is more than
1 litre of water per square metre.
Granada Spain is located at about 37.20°N 3.60°W.
Height above sea level 680m / 2231 feet
GRANADA CANDIDATURE FOR 19TH ICNCT
Facilities
Depending upon the number of participants, there are several choices for the meeting
venue and for accommodation options.
Carmen de la Victoria (University Residence)
Carmen, from the Arabic word Karm
(“grapevine”), is the name traditionally
given in Granada to the private pleasure
gardens located in the surroundings of the
city. The Carmen de la Victoria became a
property of the University of Granada in
1945.
The Carmen de la Victoria is located in
the Albayzín Hill, in the Arab quarter Axaris,
which has been full of orchards, gardens and
cármenes since the Arabs inhabited Granada.
The Albaycin is the oldest part of the city and
the whole quarter is included in the UNESCO’s
world heritage.
The Carmen has beautiful views to the
Alhambra and it is at 15 minutes walk to the center
of the city, also reachable by city buses which stops
at the front door.
The Assembly Room, the Library and
the Meeting Room are available for work
meetings. They can host 75, 17 and 15
people, respectively, which makes them
adequate for small groups.
GRANADA CANDIDATURE FOR 19TH ICNCT
Guest accommodation is also possible in the Carmen de la Victoria, with room and full
board. There are 32 single and double rooms in the Carmen de la Victoria.
All the private rooms include a bathroom, central heating, cable-TV and Wi-Fi
net service. Guests are also able to use the library, the Meeting Room and the
Assembly Room, as well as the four computers with Internet access.
Prices per room and per day. The room price includes full room and board.
Room
SINGLE ROOM €60,00
DOUBLE ROOM €84,00
SUITE CARMEN DE LA VICTORIA €114,00
TRIPLE ROOM €107,00
Web site: http://carmendelavictoria.ugr.es/
Faculty of Sciences
The Faculty of Sciences is located in the modern part of the city, near the very city
center (10 minutes walking)GRANADA CANDIDATURE FOR 19TH ICNCT
This has many very comfortable rooms appropriate for meetings of different
sizes: from the Aula Magna (which holds a capacity of 600) to the salón de grados of
80, and a variety of spaces for coffee breaks, poster presentations, etc.
There are many hotels close to the Faculty of Sciences:GRANADA CANDIDATURE FOR 19TH ICNCT
Hotel Granada Center (****)
This hotel, located just in front of the Faculty of Sciences, have special rates
(from 75 Eur per double room, including breakfast) for University visitors, which
applies for congress attendants. Congress lunches can be organized there, because of
the large restaurants and convenient prices of menus.
The hotel offers a total of 169 rooms and suites all of which are equipped with
comfort and luxury. The hotel's gastronomic offering is the Al-Zagal restaurant, which
boasts a high quality cuisine. Along with the restaurant, the hotel also offer guests a
cafeteria and a Pub.
The MICENTER convention center located in Hotel Granada Center offers a high
level professional service that guarantees the complete success of a social or business
event.
Hotel Maciá Condor (****)
El Hotel Maciá Cóndor, which is in the way from the Faculty of Sciences to the
city center, offers 104 room, 8 of them for families, with full bathroom TV, free Wi-Fi,
and air conditioning. Rates from 50 Eur/night.
Also has meeting facilities and a large restaurantGRANADA CANDIDATURE FOR 19TH ICNCT
Hotel NH Victoria (****)
Superb location at the
center of the city, near the
monuments and the shopping
centers. Has 69 rooms. Restaurant
of NH Victoria has an elegant
ambience and a cuisine that fuses
Granadian tradition with modern
innovation. Its Salón Real meeting
room can accommodate up to 90
people in a stylish and functional
space.GRANADA CANDIDATURE FOR 19TH ICNCT
Hotel AC Palacio de Santa Paula (*****)
AC Palacio de Santa Paula Autograph Collection is located in the historic center
of Granada near the Albaicín and Sacro Monte areas, the Cathedral and the Royal
Chapel, the historical Gardens of the Triumph, the Archeological museum and, of
course, the Alhambra. The beautiful AC Palacio de Santa Paula Hotel, declared an
historic and artistic monument, is a restoration masterpiece. The Hotel occupies the
premises of what used to be the Santa Paula Convent and the Casa Morisca in the XVI
and XII centuries respectively. This luxury hotel in Granada, has also a restaurant, “El
Claustro”, located in what used to be the Santa Paula convent refectory, and offers
guests haute cuisine that fuses elements of traditional Andalusian gastronomy with
modern culinary concepts. The hotel offers guests a wide variety of services such as a
fitness center, Turkish bath and sauna. It has 75 bedrooms fully equipped with
everything guests might require for a pleasant stay in one of the best five star hotels in
Granada.GRANADA CANDIDATURE FOR 19TH ICNCT
Granada Congress Centre
This is the most suitable venue for a ICNCT conference.
Situated near the city center, this modern congress center has many facilities
for meetings with a large number of participants: two huge auditoriums, three
medium-sized halls, and smaller seminar rooms.
This center is also very well communicated with the rest of the city by bus and
metro lines and with a direct bus to the airport.
There are many hotels adjacent to this center, those closest are Hotel Saray
(****):
http://www.hotelgranadasaray.com/
and Hotel Spa Senator Granada****:
http://www.senatorgranadaspahotel.com/GRANADA CANDIDATURE FOR 19TH ICNCT
which may accommodate all the attendants to the congress, within 200 meters from
the congress center. This part of Granada is also full of typical bars, restaurants and
shops.
In the next map, location of all the places aforementioned are displayed
(correction: Hotel San Anton means hotel Spa Senator)GRANADA CANDIDATURE FOR 19TH ICNCT
Organizing committees
The present proposal is presented by Ignacio Porras, Chair of the Department of
Atomic, Molecular and Nuclear Physics of the University of Granada, and member of
the ISNCT. He will be the main responsible of the organization. The Local Organizing
Committee will be formed by the persons listed at the beginning of the proposal.
The ISNCT is more than welcome to contribute to the organization, especially
for the election of the International Organizing Committee. For this purpose, we plan
to establish a continuous exchange of information with the ISNCT Executive Board and
the Board of Councillors for this conference.
Abstracts and proceedings
We will continue the procedure followed by the previous ICNCT meetings. A Call for
abstracts will be published in the meeting web site with an advance of more than six
months and distributed by e-mail to all the BNCT community.
Abstract will be reviewed by members of the international organizing
committee and experts in the field.
The book of abstract will be published either by one of the Spanish journals or
by the University of Granada Press, with an ISBN or ISSN number, previously to the
conference. A copy of the book of abstracts will be distributed with the conference bag
when registering.
As in previous meetings, contacts will made with Elsevier for publishing the
proceedings of the conference (extended papers) as a Special Issue of Applied
Radiation and Isotopes, a few months after the celebration of the conference.
Presentations
The contributions to the meeting will follow the same categories as in the previous
meetings:
Plenary lectures (by invitation)
Contributed talks (selected from the abstract received)
Posters (with short oral announcements)GRANADA CANDIDATURE FOR 19TH ICNCT
If the number of presentations allow it, parallel sessions will try to be reduced
as much as possible. The interdisciplinary spirit of BNCT makes lectures from a
particular specialized field be potentially interesting for experts of a related one.
Social programme
Welcome reception with a music performance at “La Luna” (terrace of the Congress
Palace)
Guided visit to the Cathedral of Granada and Royal Chapel (where the tombs of the
Catholic Kings are).
Guided night visit to the Alhambra
Excursion to Sierra Nevada (top mountain of Spanish peninsula, 30 km from Granada)
or to the beach (70 kms. from Granada)
Conference dinner (an interesting option is at La Chumbera, which, if weather allows,
will be hold al fresco in the large terrace with magnificent views of the Alhambra and
the city, ending with a Flamenco Show).
Banquet at the
terrace of
La ChumberaGRANADA CANDIDATURE FOR 19TH ICNCT
Sponsors
In addition to the support from the ISNCT, different sponsors will be contacted.
The Department of Atomic, Molecular and Nuclear Physics, the Faculty of Sciences
and the University of Granada usually contributes to international scientific meetings.
Funds will be also asked to the Junta de Andalucía (regional government) and to
biotechnological companies located in the Health Sciences Technology Park of
Granada. Sponsors of the last Young Researchers meeting hold in 2013, as ACS
Foundation and Mitro Company will be welcome to participate too. Strong efforts will
be done for seeking funds from international companies with interest in BNCT.
A detailed tentative budget of the Conference will be presented to the
Executive Board and the Board of Councillors before the 17th ICNCT conference at
Columbia, MO. Our aim is to not increase the registration fees from the latest
conference in any of their modalities. Possibly, due to the local prices, they can be
reduced.
Supporting Agency
For the organization of this complex meeting, we rely, as for the 7th Young
Researchers’ meeting hold in 2013, in the Travel Agency Viajes el Corte Inglés, which
has a strong experience and professionality and which guarantees the success of the
event. As an annex please find the brochure from the Travel Agency with all the
possibilities for services related to the conference with estimated prices.
Ignacio Porras
Departamento de Física Atómica, Molecular y Nuclear
Facultad de Ciencias
Av. Fuentenueva s/n
Universidad de Granada
E-18071 Granada, Spain
Tel. +34 958240030
FAX +34 958249487
e-mail: porras@ugr.esYou can also read
