HPV & Vaping Tackling Dentistry's Oral Health & Communication Game Changers - Presented by Catrice Opichka, RDH, MS - PO Box 325, Bow WA, 98232 | ...
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HPV & Vaping Tackling Dentistry’s Oral Health & Communication Game Changers Presented by Catrice Opichka, RDH, MS PO Box 325, Bow WA, 98232 | 920.246.4165 | catrice@pureeducation.org
E-Cigarettes ENDS - Electronic Nicotine Delivery System ____________________________________ Developed: 2003 ~ Available in US: 2006 E-Cigarette Components ____________________________________ E-Cigarettes all contain a BATTERY, ATOMIZER & CARTRIDGE. ____________________________________ st 1 Generation ~ Cig-a-Likes v Same size as a regular tobacco cigarette ____________________________________ v Heavier than a traditional cigarette. v Manual – must hold button to operate. ____________________________________ v Typically disposable. v Inexpensive. ____________________________________ v Good for about 200-300 puffs nd 2 Generation ~ Mid-Size Electronic Cigarettes ____________________________________ v Slim pen like style. v Manual or Automatic - press button or inhale to activate. v Larger capacity battery (3-7 times larger). ____________________________________ v Good for one to two days. 3rd Generation ~ Advanced Personal Vaporizers. ____________________________________ v Many different sizes and shapes. v Typically larger than Gen 1 & 2. ____________________________________ v Manual fire button. v Advanced brain or power source. ____________________________________ v Two types of 3rd Gen Mods. 1. Mechanical Mods ____________________________________ § Simple device. § No electronic circuitry. § Features a fire button, battery ____________________________________ compartment, connector. 2. Regulated Mods ____________________________________ § Complex systems. § Allows vapor to modify the voltage and ____________________________________ wattage output. § Electrical resistance meters. ____________________________________ § Reverse battery polarity protection. 4th Generation ____________________________________ v Automatic temperature control. v Low ohm builds. ____________________________________ v Sub – ohm clearomizers (re buildable tanks) Vaping Statistics ____________________________________ v 4o million Americans smoke E-cigarettes. v 2019 study stated that 1 in 20 Americans use E-cigarettes. ____________________________________ v 1 billion users globally. v E-Cigarettes today – 3 billion-dollar industry. ____________________________________ JUULS & JUULING ____________________________________ v Introduced in 2007. v Developed by Stanford Grad Students. v 500+ brands available today – in 2018 JUUL became the top seller.
v Popular because of their small size – about the size of a flash ____________________________________ drive. v Popular due to low cost – Starter Kit $50. ____________________________________ v Each pod contains 40mg- 59mg of nicotine – about 200 puffs – same nicotine as one pack of cigarettes. ____________________________________ VA21 – VAPING SMOKESCREEN ARTICLE ____________________________________ e-Cigar ____________________________________ v 1-cartridge = 20 cigars. v Uses the same technology as e-cigarettes. ____________________________________ v Flavors include cherry, vanilla, Irish cream, coffee, chocolate, rum. One Coil vs Two Coils ____________________________________ v One coil releases more chemicals. v Vapor temperature & density, flavor intensity, throat hit ____________________________________ increased with dual coils. v Throat hit is the feeling in the back of the throat. ____________________________________ v Ranges from tingle to burn. ____________________________________ E-CIGARETTE INGREDIENTS Suspension Ingredients ____________________________________ PROPYLENE GLYCOL (PG) v Thick synthetic colorless liquid base in e-juice. v Penetration enhancer – alters the structure of the skin. ____________________________________ v Increases the ability of the product to reach the bloodstream. ____________________________________ VEGETABEL GLYCERIN / GLYCEROL (VG) v Thick synthetic liquid. ____________________________________ v Thicker and sweeter than Propylene glycol. v Decreases throat hit. ____________________________________ PG vs. VG v PG and VG have different consistencies. ____________________________________ v Contribute different tastes to e-juice. v Vapor plumes are less dense with PG but flavor sweeter. ____________________________________ v Many e-liquids use both. DIETHYLENE GLYCOL v FDA tests in 2009 found trace amounts. ____________________________________ v Colorless, odorless, poisonous liquid. v Used as a solvent in antifreeze. ____________________________________ v Human Carcinogen. People are Dying ____________________________________ E-Cigarette / Vaping Associated Lung Injury (EVALI) v First Case: June 2019 ____________________________________ v Peak: September 2019 ____________________________________ VA29 – CDC LINK As of January 2021 ____________________________________ 2800+ cases of lung injuries have been reported. 50 states and the District of Columbia have reported lung injuries. 3
____________________________________ 68 deaths have been confirmed (as of August 2020). Ages affected from 17-75. ____________________________________ Bronchoalveolar Lavage (BAL) fluid from lung injury patients have ____________________________________ been collected. Findings: v THC found in 82% of the samples. ____________________________________ v Nicotine found in 62% of the samples. v Vitamin E acetate found in nearly all of the samples (48 of ____________________________________ 51). Conclusion is that Vitamin E acetate is at least in part the reason for ____________________________________ the lung injury. More investigation to see if other chemicals are involved. ____________________________________ Vitamin E acetate is naturally found in foods like: ____________________________________ v Vegetable Oils v Cereals ____________________________________ v Meat v Fruits v Vegetables ____________________________________ Vitamin E acetate is added to: v Dietary Supplements ____________________________________ v Cosmetics v Skin Creams ____________________________________ Vitamin E acetate does not cause harm when ingested or applied to the skin: however, it can be toxic when inhaled. ____________________________________ Product Findings 152 different THC-containing products were reported by EVALI ____________________________________ patients. v Dank Vapes most reported @ 56% (Northeast and South) v TKO @ 15% and Smart Cart @ 13% most reported (West) ____________________________________ v Rove @ 12% most reported (Midwest) Chronic medical conditions can increase the risk of EVALI, re- ____________________________________ hospitalization, and death. v Cardiac disease. ____________________________________ v Chronic pulmonary disease. v Diabetes. ____________________________________ Flavoring Ingredients ____________________________________ DIACETYL v Chemical used to create intense buttery flavor microwave ____________________________________ popcorn. v Hazardous when heated. v Added to e-juice to strengthen flavor. ____________________________________ v Found in 39 of 51 tested e-liquid brands in a 2015 study. v Commonly found in vanilla, caramel, and coconut flavor. ____________________________________ 4
v American Lung Association states that vaping can cause ____________________________________ popcorn lung. v Popcorn lung is a condition otherwise known as Bronchiolitis ____________________________________ Obliteranes (BO). v It is an obstruction of the smallest airways in the lungs. ____________________________________ v Symptoms - dry cough, shortness of breath, wheezing, tired. v This is an irreversible condition. ____________________________________ VA21 – AMERICAN LUNG ASSOCIATION LINK ____________________________________ Chemicals Possibly Released in the Vapor Production Latest E-cigarette Research ____________________________________ v Vaped e-liquids undergo pyrolysis and generate oxidative species. v Can lead to the formation of additional toxic components. ____________________________________ v Can lead to the formation of formaldehyde, acetaldehyde ____________________________________ and acrolein. ____________________________________ VA26 – AMERICAN LUNG ASSOCIATION ARTICLE FORMALDEHYDE ____________________________________ v Colorless, odorless, poisonous gas. v Released when Propylene glycol (PG) is heated. ____________________________________ v Exposure is known to cause nasopharyngeal cancer. v Human carcinogen. ____________________________________ Says Who??? § 1987 – US Environmental Protection Agency (EPA). ____________________________________ § International Agency for Research on Cancer. § 2011 National Toxicology Program. ____________________________________ § National Cancer Institute. § National Institute of Health. § Occupational Safety and Health (OSHA). ____________________________________ ACETALDEHYDE v Chemical byproduct of vapor production. ____________________________________ v Toxic irritant. v Breaks down in the kidneys. ____________________________________ v Human carcinogen. v With alcohol – increased risk of upper GI and liver cancers. ____________________________________ ACROLEIN v Chemical byproduct of vapor production. ____________________________________ v Also found in tobacco cigarettes. v Proven to contribute to lung cancer. ____________________________________ v Mutates tumor suppressor gene p53. v Cytotoxicity in the airways. v 2014 report in Addiction Review states PG releases Acrolein ____________________________________ when heated. ____________________________________ VA23 – CONTENT & SAFETY ARTICLE Other Ingredients METAL 5
v Released when heating coils are activated. ____________________________________ v Lead, chromium, nickel, manganese. v Potential to cause lung tissue damage ____________________________________ VA21 – VAPING SMOKESCREEN ARTICLE ____________________________________ NICOTINE v Stimulant. ____________________________________ v Reaches the brain within 20 seconds of inhalation. v Increases blood pressure. ____________________________________ v Increases blood sugar levels. v Addictive. ____________________________________ Nicotine Levels in E-cigarettes v High – 36 mg. v Medium – 24 mg. ____________________________________ v Low – 12 mg. v Zero – No nicotine. ____________________________________ § (a dozen independent studies found nicotine in zero nicotine e-cigarettes) ____________________________________ § Nicotine Levels in tobacco cigarettes § 8 mg. – 20mg. ____________________________________ § Average tobacco cigarette is 12 mg. v 2017 Psychopharmacology study tested 8 different brands of ____________________________________ vaping devices. v Discovered that despite similar nicotine levels, different amounts of nicotine were delivered. ____________________________________ VA22 – NICOTINE DELIVERY DIFFERENCES ARTICLE ____________________________________ v 2016 study showed that consumption of e-liquid was ____________________________________ doubled in low vs. high nicotine condition. v Conclusion was that individuals self-titrate by adjusting puffing behavior to maximize nicotine delivery. ____________________________________ VA24 – SELF-TITRATION ARTICLE ____________________________________ Smoking Cessation ____________________________________ v The American Cancer Society states that 80.5% of all smokers trying to quite using e-cigarettes use both cigarettes and e-cigarettes at the same time. ____________________________________ v A 2015 study suggests a positive correlation between e- cigarette use and deduced nicotine withdrawal symptoms. ____________________________________ VA25 – SMOKING CESSATION ARTICLE ____________________________________ VL13 – CDC LINK VA27 – CDC ARTICLE ____________________________________ VL12 – CNBC REPORT ____________________________________ E-cigarette Explosions ____________________________________ v Increasing reports of lithium ion battery explosions injuring mouth, face and hands. 6
Vaping Regulations ____________________________________ v Tobacco is regulated by the Federal Government. v In 2017 the FDA mandated several new regulations. ____________________________________ § Nicotine is addictive warning on labeling. § Nicotine is addictive sheets in stores. ____________________________________ § New labeling of “Manufacturer” for shops that mix their own e-liquid. v In 2018 the FDA begins creating & implementing regulations. ____________________________________ § Manufacturing, Import, Packaging, Labeling, Advertising, Promotion, Sales, Distribution. ____________________________________ § As of March, 2018 none of these policies have been completed. ____________________________________ § www.FDA.gov Search for latest guidelines and regulations under the “guidance” tab. ____________________________________ v FDA Regulation Delays § New regulation that E-cigarette companies must submit ____________________________________ product ingredients has been delayed from the initial proposal of 2018 to 2020. ____________________________________ VL11 – AMERICAN LUNG ASSOCIATION LINK ____________________________________ v FDA Regulations (Active) § April 6, 2018 – “Large-scale undercover nationwide blitz” ____________________________________ on illegal sales of e-cigarettes to minors for both online and in-store sales. § Working with eBay to prevent future listing of JUUL ____________________________________ products on its website. ____________________________________ VA20 – FDA CRACKDOWN ____________________________________ Smoking Today CDC Report states that there are less smokers today than in the last 22 years. ____________________________________ v Youth Risk Behavior Survey of Adolescents Experimenting with Tobacco: ____________________________________ § 70% - 1991 § 58.4% - 2003 ____________________________________ § 28.9% - 2017 VA21 – VAPING SMOKESCREEN ____________________________________ Vaping Today ____________________________________ § 28.9% adolescents reported trying smoking in 2017. § 42.2% of the same age group reported vaping in 2017. ____________________________________ VA21 – VAPING SMOKESCREEN ____________________________________ Side Effects v Dry skin, xerostomia, rash or burning sensation on face, ____________________________________ caffeine sensitivity, minor bloody nose issues, puffy and dry eyes, throat irritation, dry cough, hoarseness, oral ulcers, ____________________________________ dizziness. 7
What the heck is vaping? ____________________________________ Vape – verb – inhale and exhale the vapor produced by an electronic cigarette or similar devices. ____________________________________ Teens & Vaping ____________________________________ v Teens prefer vaping over smoking. v Vape pens can be customized. ____________________________________ What is dabbing? Dabbing – verb – to inhale vapor of highly concentrated ____________________________________ cannabinoids. v Called oil, wax, budder, BHO (butane has oil), shadder. ____________________________________ What is dripping? ____________________________________ Dripping – verb – to drip liquid nicotine directly on the heating coils of the e-cigarette. ____________________________________ v Generates higher coil temps. v Greater release of chemicals. ____________________________________ v Increased “shots” of nicotine. Hookah Bar Bonus ___________________________________ v Shisha is soaked in molasses or honey and mixed with fruit. v Shisha contains nicotine and other similar chemicals to ____________________________________ cigarette smoke. v Smoking tobacco through water does not filter out cancer ____________________________________ causing chemicals. v Ina 60 minute Hookah session, smokers are exposed to 100- ____________________________________ 200 times the volume of smoke inhaled from a single cigarette. ____________________________________ ____________________________________ Smoking Cessation Resources Centers for Disease Control and Prevention | cdc.gov American Heart Association | heart.org ____________________________________ Smoke Free | smokefree.gov ____________________________________ Additional Resources ____________________________________ FDA REGULATIONS & VAPING TIMELINE ____________________________________ VL15 – FDA REGULATIONS ___________________________________ VL18 – VAPING TIMELINE 8
HPV and Oral Cancer 2021 Cancer Statistics ____________________________________ 14 million people have cancer in the United States alone. Worldwide cancer rates are estimated to jump 75% by the year 2030. ____________________________________ HL50 – CANCER STATISTICS LINK ____________________________________ Why? v Aging population. ____________________________________ v Lifestyle cancers. Lifestyle Cancer A cancer that increases in risk due to behavioral factors based on ____________________________________ lifestyle choices. 1. Sun Exposure ____________________________________ § Malignant skin cancer is the largest diagnosed lifestyle cancer in the U.S. and abroad. ____________________________________ § 3.5 million skin cancers are diagnosed annually in the United States. ____________________________________ § Skin cancer makes up for more than breast cancer, colon cancer, and lung cancer combined. ____________________________________ § 1 in 5 Americans will be diagnosed this year alone. ____________________________________ Skin Cancer Resources | Skin Cancer Foundation www.skincancer.org /cancer-information/skin-cancer-facts ____________________________________ 2. Drinking Alcohol ____________________________________ § Mouth, pharynx, larynx, esophagus, liver, colon, rectum, breast. ____________________________________ 3. Obesity § Esophagus, pancreas, ovarian, colon, rectum, ____________________________________ endometrial, kidney, thyroid, breast. 4. Cigarette Smoking ____________________________________ § Mouth, throat, lung, kidney, bladder, pancreas, stomach, cervix. ____________________________________ Oral cancer is a “lifestyle cancer” because lifestyle behaviors or choices influence the percentage of risk an individual has for cancer. ____________________________________ 2020 Oral Cancer Statistics v 53,000 Americans will be diagnosed in 2018 with oral cancer. ____________________________________ v 9,000 people will lose their battle with oral cancer this year. v Someone dies from oral cancer every hour. ____________________________________ HL51 – ORAL CANCER STATISTICS LINK ____________________________________ Our Role in Oral Cancer Prevention and Care v HPV Communication ____________________________________ v Oral Cancer Exam / Early Cancer Detection § According to the American Dental Association, 53% of ____________________________________ the US population (adults) visits a dentist every year. 9
HL52 – ADA STATISTICS LINK § We have an abundance of opportunities to diagnose oral ____________________________________ cancer early. v Patient Care – Before, During, After Cancer Treatment ____________________________________ HL54 – RDH MAGAZINE SCREENING LINK ____________________________________ Traditional Risk Factors v Smoking, Chewing Tobacco & Heavy Alcohol are ____________________________________ traditional risk factors for oral cancer. v Cancers are found in the floor of the mouth and the ____________________________________ lateral boarders of the tongue. v 90& are squamous cell carcinomas. ____________________________________ v Cancers are typically diagnosed in stages 3-5. v Average patient age of diagnosis is 62 years old. ____________________________________ v Smoking & Drinking together increases risk by 15%. st 21 Century Oral Cancer Risk Factor ____________________________________ v Human Papilloma Virus has become a rapidly increasing risk for throat cancers. ____________________________________ v HPV 16 & 18 are the most common strains that cause oropharyngeal cancers. v 79 million Americans are currently infected. ____________________________________ v CDC states that nearly everyone who is sexually active will have an HPV infection within their lifetime. ____________________________________ v Cancers are found in posterior of mouth - tonsils, tonsillar pillar, base of tongue and oropharynx. ____________________________________ v Cancers are often found in individuals who have never smoked or used chewing tobacco. ____________________________________ HL53 – CDC STATISTICS LINK ____________________________________ Oral Cancer Studies v Oral cancer has a higher death rate than: ____________________________________ § Cervical Cancer § Hodgkin’s Lymphoma ____________________________________ § Laryngeal Cancer § Testicular Cancer ____________________________________ § Thyroid Cancer Oral Cancer Epidemiology v Men are twice as likely to get oral cancer than women. ____________________________________ Women’s risk has increased greatly in the last couple of decades. ____________________________________ v The average age of oral cancer diagnosis has decreased to under 40 years old. ____________________________________ HL56 – ORAL CANCER EPIDEMIOLOGY ____________________________________ HPV Strains v There are over 200 strains of HPV. v Most of the strains cause skin warts and non-cancerous lesions. 10
v 40 strains are mucosal strains and can affect the oral ____________________________________ cavity. ____________________________________ v Approximately a dozen strains have moderate or high cancer-causing abilities. ____________________________________ The Human Papilloma Virus contributes to the following cancers: Cervical Cancer 91% ____________________________________ Vulvar Cancer 69% Vaginal Cancer 75% ____________________________________ Penile Cancer 63% Anal Cancer 91% (93%, 89% Male) ____________________________________ Oropharyngeal Cancer 70% (63% Female, 72% Male) ____________________________________ Centers for Disease Control and Prevention 2021 ____________________________________ Frequently Asked Questions About HPV 1. How do you know if you have HPV? ____________________________________ 2. How long does it take to fight HPV? 3. Does HPV 16 & 18 always cause cancer? ____________________________________ 4. How does HPV Cause Cancer? Dental Oncology Professionals ____________________________________ Dr. Dennis Abbott drdennisabbott@dopnt.com ____________________________________ 214-240-4968 ____________________________________ Who Gets Oral HPV v Research collected and presented by professors at John ____________________________________ Hopkins Bloomberg School of Public Health show that men have a greater risk of oral HPV. ____________________________________ v These studies show that risk is higher even when behaviors are the same. ____________________________________ HA52 – CDC WEBINAR SLIDES ____________________________________ HPV Testing in the Dental Practice v Research shows that Oral DNA testing is a reliable tool for ____________________________________ testing current HPV strains. v Use in the dental setting can be risky due to lack of time and dedicated personnel needed for proper consultation. ____________________________________ HA50 – SALIVA TESTING ARTICLE ____________________________________ HPV and Sexual Behavior ____________________________________ You can get the HPV virus in the following ways: v Vaginal sex. v Anal sex. ____________________________________ v Oral sex. Not Getting Vaccinated & Multiple Sexual Partners increase the risk of HPV. 11
HPV Vaccine Two companies provide three options for HPV vaccination. Cervarix Gardasil Gardasil 9 ____________________________________ HPV 16 & 18 HPV 6, 11, 16, 18 HPV 6, 11, 16, 18 31, 33, 45, 52, 58 ____________________________________ June 2009 Girls June 2006 Girls December 2010 December 2014 Boys Girls & Boys ____________________________________ HPV Vaccine Resistance ____________________________________ Common Side effects for HPV include: Pain, swelling, itching bruising, nausea, dizziness, vomiting, pain in legs and muscles. ____________________________________ According to research done by Tierona Low Dog M.D. ____________________________________ 67 million doses of the HPV vaccine were given between June 2006 - March 2014, and in that time, 25,000 adverse events were reported. ____________________________________ “After careful review, none of these adverse events were any more common after HPV vaccination than among comparison groups”. ____________________________________ For more information on HPV vaccination safety: ____________________________________ HL55 – CDC – Vaccine Adverse Event Reporting Systems ____________________________________ Frequently Asked Questions About HPV Vaccine 1. When should people get the HPV vaccine? 2. What if I already got myself/my child Gardasil…do I/they ____________________________________ need Gardasil 9? 3. Why can’t a person over 26 get vaccinated? ____________________________________ 4. How much does it cost and does insurance cover the vaccine? ____________________________________ Assessment of Vaccination Rates and Attitudes of the Future v Millennials are the first group of future policy makers to ____________________________________ have been vaccinated. v Studies show positive attitudes toward HPV vaccination, at ____________________________________ least among med students surveyed. HA51 – MILLENNIAL MED STUDENT VACCINATION ARTICLE ____________________________________ Social Stigma / Sexual Behaviors ____________________________________ It is difficult for parents to imagine their children sexually active; however, the changing sexual behaviors of our teens have made HPV ____________________________________ impossible to ignore. Teens & Sex Percentage of teens having sex in the United States: ____________________________________ 7% by 12-13 28% by 15 ____________________________________ 48% by 17 61% by 18 12
80% of sexually active people ages 14-44 have had oral sex with an ____________________________________ opposite sex partner. ____________________________________ Individuals admit to not using condoms during oral sex. ____________________________________ Frequently Asked Questions About Oral HPV v Do condoms prevent oral HPV? v Can you get oral HPV from deep kissing? ____________________________________ ____________________________________ HPV Education in the Dental Practice “HPV education is like climbing a mountain” ____________________________________ Catrice Opichka, RDH ____________________________________ vChoose a Guide § Hire or choose a guide. ____________________________________ § Doctor, member of the team, consultant. § Someone needs to be responsible for making the team ____________________________________ accountable for HPV education and follow-through. vAssemble Your Team § The entire team needs to understand the importance of ____________________________________ oral cancer detection and be proficient in their HPV communication. ____________________________________ vStart at Basecamp § Make decisions on how you want HPV education to look ____________________________________ in YOUR practice. § How much freedom will your team have to ____________________________________ decide when and how to educate patients? § Will you provide formal training for your ____________________________________ team? § Who will deliver the training? v Create the Map ____________________________________ § Create written protocol. § This should include adding health history ____________________________________ questions about HPV. • Have you received the vaccination for ____________________________________ HPV? • Have you had the Cervarix or Gardasil ____________________________________ vaccine? • Have you ever been diagnosed with ____________________________________ HPV? • Have you been treated for an HPV- ____________________________________ related cancer? § Educational materials provided for patients. ____________________________________ • Brochures for new patient packet. • Brochures for after oral cancer (head and neck) exam. ____________________________________ • Brochures in the waiting area. § Consent form (optional). ____________________________________ • Decide if you will use a consent form. • Create the consent form. 13
• Decide who will receive the form (example: for all Cancer Resources patients under 18 years Oral Cancer Foundation | www.oralcancerfoundation.org old). American Cancer Society | www.cancer.org § Website list for patients to National Cancer Institute | www.cancer.gov/cancertopics research on their own. § Create verbal protocol. ____________________________________________ § This should include team education on correct verbiage for HPV education. ____________________________________________ vTrain and Practice § Doctors and Hygienist - pathology course ____________________________________________ every other § year. ____________________________________________ § Team review on HPV education every year. ___________________________________________ For access to my research Please visit my website www.pureeducation.org to access research articles and links. To Learn More About HPV Training for your Dental Practice www.pureeducation.org (Click the Coaching tab on the main page for details) If you have questions about this program, or just want to Reach Out Phone ~ 920-246-4165 Email ~ Catrice@PureEducation.org 14
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