HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?

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HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
 Burns                      Scabs                       Post-stitches

                                                                              Reserved for the use of medical representatives. Cannot be left-behind.
   D0        D9               D0         D10              D0            D10

 Hand-foot syndrome         Scratches                   Radiodermatitis

   D0        D10              D0         D18              D0            D21

Results obtained with CICAPLAST B5

                   LA ROCHE-POSAY. COMMITTED TO DERMATOLOGY.
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
CICAPLAST B5
 WHY IS IT SO EFFICIENT?

  3 KEY BENEFITS
   CICAPLAST B5              CICAPLAST B5             CICAPLAST B5

                                                                                Reserved for the use of medical representatives. Cannot be left-behind.
 BENEFICIAL ACTION          COMPREHENSIVE                2 ADAPTED
   ON MICROBIOTA              FORMULA:                  TEXTURES
 THANKS TO PREBIOTIC         REPAIRING and
     PROPERTIES                RELIEVING

CICAPLAST B5: ACCELERATES REPAIRING PROCESS, RELIEVES PAIN    PROVEN CLINICAL
                                                                 EFFICACY
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
CICAPLAST BAUMEB5
SIGNIFICANT EFFICACY DEMONSTRATED ON 9739 PATIENTS
AND 21 DIFFERENTLESIONS

                              CLINICAL SYMPTOMS                                                                         SUBJECTIVESYMPTOMS

                   80
                            71                                            Initial visit                                                              Initial visit
                                                                          Final visit                                                                Final visit
                   60             *

                                                                                                                                                                     Reserved for the use of medical representatives. Cannot be left-behind.
                                 54.8
    % ofpatients

                                                                                          Score(0-10)
                                                            43.7
                                              40.2
                   40                                                                                                        4.5
                                                                                                                3.8
                                                      *                                                                                  3.1         3.2
                                                     22.5            *
                   20                                              17.4
                                                                                                                                    *                       *
                                                                                                                       *           0.7          *          0.4
                                                                                                                      0.3                      0.3
                    0
                           Erythema          Desquamation    Cracks                                              Burning     Tightness    Pain       Itching

                        *p 2 applications / day, during 16 days
> Lesions: irritative dermatitis, cracks, scabs, chelitis, nappy rashs, cryotherapy...
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
NEW PUBLICATIONS ASSESSING THE ROLE OF SKIN MICROBIOTA
  INTHE HEALING PROCESS
          ✓ Damaged skin results in changes in skin microbiota composition
          ✓ Modulating skin microbiota promotes the healing process

                                                                      IMPAIRED MICROBIOTA                                         BALANCEDMICROBIOTA

                                                                                                                                                                  Reserved for the use of medical representatives. Cannot be left-behind.
                                                                     AN UNBALANCEDMICROBIOTA                                        A BALANCEDMICROBIOTA
                                                                             LEADS TO:                                                    ALLOWS TO:

                                                                     - SLOW DOWN healing process                                  - ACCELERATE healing process*
                                                                     - MORE inflammation                                          - CONTROL inflammation**
                                                                     - HIGHER infectious risk                                     - DECREASE infectious risk**

*P. LJM Zeeuwen and al., Microbiome dynamics of human epidermis following skin barrier disruption, Genome Biology 2012.
T.R. Johnson and al., The Cutaneous Microbiome and Wounds: New Molecular Targets to Promote Wound Healing, Int J Mol Sci. 2018.

**J. L. Linehan and al., Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair,Cellpress 2018.
T.R. Johnson and al., The Cutaneous Microbiome and Wounds: New Molecular Targets to Promote Wound Healing, Int J Mol Sci. 2018.
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
HOW CAN CICAPLAST B5 MODULATE SKIN MICROBIOTA?

                      THANKS TO TWO PREBIOTIC INGREDIENTS
          that stimulate cutaneous microbiota growth and /or activity

                       LaRoche-Posay                                                        Panthenol 5%

                                                                                                                                                            Reserved for the use of medical representatives. Cannot be left-behind.
                       Thermal water

PREBIOTIC PROPERTIES:                                                        PREBIOTIC PROPERTIES:

   REBALANCES SKIN MICROBIOTA                                                   SUPPORTS BACTERIA MODULATION
   IMPROVES BACTERIALDIVERSITY OF THE SKIN                                      INHIBITS STAPHYLOCOCCUS AUREUSGROWTH

                                                                             Chohnann S,Murase M, KurikawaK, Higashi K, Ogata Y,Antimicrobial
Zeichner J,Seité S,From Probiotic to Prebiotic Using Thermal Spring Water.   Activity of Pantothenol against Staphylococci Possessing aProkaryotic TypeII
Journal of Drugs in Dermatology 2018 ;17:6,49-53.                            Pantothenate Kinase. Microbes Environ. 2014; 29:2, 224-226.
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
CICAPLAST BAUME B5 A COMPREHENSIVE FORMULA

                                 ACCELERATES REPAIR
                                  [MADECASSOSIDE]
         Stimulates the production of cutaneous fibers:                                                            RELIEVES PAIN
         Collagen I, II, GAG
                                                                                                                  [PANTHENOL 5%]
         Regulates keratinocyte renewal

                                                                                                                                                    Reserved for the use of medical representatives. Cannot be left-behind.
                                                                            Clinically proven soothing action: decreases painful sensations
                                Quicker healing: gain of 2 days             p Randomised, 12 patients, 22 days.                                                 > Multicentric observational study. Visit at D0 and D15-30.
  > Artificial creation of an epidermal wound by suction blisters method.             > 550 dermatologists and pediatricians.
  > Products applied: 1 / day, during 22 days.                                        > 2440 patients with lesions or irritations.
  > Measurement of healing process: Fringe projection technic, TEWL                   > Average age = 36.7 years old.
    measurement by Tewametry, Chromameter.
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
CICAPLAST B5
A COMPLETE RANGE TO ACCELERATE AND IMPROVE QUALITY
OF WOUND HEALING PROCESS
  SKINCARE                                          HYGIENE
 DAILY INJURIES                                    PURIFYING FOAMING CLEANSER
 AFTER PROCEDURES
 Creamy texture
                                                   CICAPLAST LAVANT B5

                                                                                Reserved for the use of medical representatives. Cannot be left-behind.
 CICAPLAST
 BAUME B5

                                                    NEW
                                                   AFTER STITCHES REMOVAL
 CICAPLAST                                         AFTER PROCEDURES
 BAUME B5                                          Invisible gel texture
 SPF50
                                                   CICAPLAST GEL B5

 Body, Face and Scalp                              Body, Face and Scalp

                        LA ROCHE-POSAY. COMMITTED TO DERMATOLOGY.
HOW DO YOU TAKE CARE OF THESE SKIN LESIONS? HOW DO YOU TAKE CARE OF THESE SKIN LESIONS? HOW DO YOU TAKE CARE OF THESE SKIN LESIONS?
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