Guide to Infection Prevention in Emergency Medical Services
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APIC Implementation Guide Guide to Infection Prevention in Emergency Medical Services About APIC APIC’s mission is to create a safer world through prevention of infection. The association’s more than 14,000 members direct infection prevention programs that save lives and improve the bottom line for hospitals and other healthcare facilities. APIC advances its mission through patient safety, implementation science, competencies and certification, advocacy, and data standardization.
About the Implementation Guide series APIC Implementation Guides help infection preventionists apply current scientific knowledge and best practices to achieve targeted outcomes and enhance patient safety. This series reflects APIC’s commitment to implementation science and focus on the utilization of infection prevention research. Topic-specific information is presented in an easy-to- understand-and-use format that includes numerous examples and tools. Visit www.apic.org/implementationguides to learn more and to access all of the titles in the Implementation Guide series. Copyright © 2013 by the Association for Professionals in Infection Control and Epidemiology, Inc. (APIC) All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopied, recorded, or otherwise, without prior written permission of the publisher. Printed in the United States of America First edition, January 2013 ISBN: 1-933013-54-0 All inquiries about this guide or other APIC products and services may be directed addressed to: APIC 1275 K Street NW, Suite 1000 Washington, DC 20005 Phone: 202-789-1890 Fax: 202-789-1899 Email: info@apic.org Web: www.apic.org Email: info@apic.org Web: www.apic.org Disclaimer APIC provides information and services as a benefit to both APIC members and the general public. The material presented in this guide has been prepared in accordance with generally recognized infection prevention principles and practices and is for general information only. It is not intended to provide, or act as a substitute for, medical advice, and the user should consult a health care professional for matters regarding health and/or symptoms that may require medical attention. The guide and the information and materials contained therein are provided “AS IS”, and APIC makes no representation or warranty of any kind, whether express or implied, including but not limited to, warranties of merchantability, noninfringement, or fitness, or concerning the accuracy, completeness, suitability, or utility of any information, apparatus, product, or process discussed in this resource, and assumes no liability therefore.
Guide to Infection Prevention in Emergency Medical Services Table of Contents Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Declarations of Conflicts of Interest and Disclaimer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Section 1: Guide Overview. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Section 2: Epidemiology and Pathogenesis: Infectious Diseases in EMS. . . . . . . . . . . . . . . . . . . . . . . . . 12 Section 3: Risk Factors/Risk Assessment in EMS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 Section 4: Surveillance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Section 5: Engineering and Work Practice Controls and Personal Protective Equipment . . . . . . . . . . . . 32 Section 6: Occupational Exposure Health Issues. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Section 7: Bioterrorism and Infectious Disease Emergency Preparedness . . . . . . . . . . . . . . . . . . . . . . . . 65 Section 8: Education, Training, Compliance Monitoring, and Summary. . . . . . . . . . . . . . . . . . . . . . . . 71 Appendix A: Sample Ambulance Cleaning Procedures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Appendix B: Sample Exposure Control Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 Appendix C: Definition of Terms. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Appendix D: Acronyms and Abbreviations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 Association for Professionals in Infection Control and Epidemiology 3
Guide to Infection Prevention in Emergency Medical Services Acknowledgments Lead Author Janet Woodside, RN, MSN, COHN-S EMS Program Manager, Portland Fire and Rescue, Portland, OR Authors Terri Rebmann, PhD, RN, CIC Associate Professor, Institute for Biosecurity, Saint Louis University, School of Public Health, Saint Louis, MO Carolyn Williams, RN, BSN Occupational Health/Infectious Disease Program Manager, City of Portland, Portland, OR Jeff Woodin, NREMT-P, FAHA Tualatin Valley Fire and Rescue, Tigard, OR Research Assistant Martin B. Schopp EMS Intern, Portland Fire and Rescue, Student Nurse, Concordia University, Portland, OR Reviewers Linda Bell, MSN, ARNP, EMT-P Programs Coordinator, Consultant Services, Middleburg, FL Greg Bruce A-EMCA CHICA-Canada, Platoon Supervisor/Infection Control Officer, County of Simcoe Paramedic Services, Ontario, Canada William E. Coll, BA, MPUB AFF, LP, REHS Clinical Commander/ICO, Austin/Travis County EMS, Austin, TX Jeffrey D. Ferguson, MD, FACEP, MS-HES, NREMT-P Assistant Professor of Emergency Medicine, Medical Director, Vidant Medical Transport, Assistant EMS Director, Pitt County, NC; Brody School of Medicine, East Carolina University, Greenville, NC Louis Gonzales, BS, LP System Coordinator – Performance Improvement and Research, Senior Science Editor, American Heart Association, Office of the Medical Director, Austin/Travis County EMS system, Austin, TX 4 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Arthur Mata Medical Coordinator, Training Division, City of Flint, Michigan Fire Department (Retired), National Fire Academy Instructor – EMS Katherine H. West, BSN, MSEd, CIC Infection Control/Emerging Concepts, Manassas, VA Production Team Managing Editor Thomas Weaver, DMD Director, Professional Practice Association for Professionals in Infection Control and Epidemiology, Inc. Project Management and Production Oversight Anna Conger Sr. Manager, Practice Resources Association for Professionals in Infection Control and Epidemiology, Inc. Layout Meredith Bechtle Maryland Composition Cover Design Sarah Vickers Art Director Association for Professionals in Infection Control and Epidemiology, Inc. Association for Professionals in Infection Control and Epidemiology 5
Guide to Infection Prevention in Emergency Medical Services Declarations of Conflicts of Interest Linda Bell, MSN, ARNP, EMT-P, serves as national faculty for the American Heart Association (AHA), serves on the AHA Task Force #3 Committee, and is owner of Community Training Center through AHA. Greg Bruce, A-EMCA, has nothing to declare. William E. Coll, BA, MPUB AFF, LP, REHS, has nothing to declare. Jeffrey D. Ferguson, MD, FACEP, NREMT-P, has nothing to declare. Louis Gonzales, BS, LP, has nothing to declare. Arthur Mata has nothing to declare. Terri Rebmann, PhD, RN, CIC, has nothing to declare. Martin Schopp has nothing to declare. Carolyn Williams, RN, BSN, has nothing to declare. Jeff Woodin, NREMT-P, FAHA, has nothing to declare. Janet Woodside, RN, MSN, COHN-S, has nothing to declare. Katherine H. West, BSN, MSEd, CIC, has nothing to declare. 6 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Disclaimer The Guide to Infection Prevention in Emergency It is the intent of APIC to enhance access of Medical Services is advisory and informational infection prevention information through the and is intended to assist and guide EMS agencies, content, references, and resources contained including Public Safety and Fire, in providing within this guide. Resources are continuously a safe workplace through effective Infection being updated, and APIC has made every Prevention programs adapted to the needs effort to present the most current information, of EMS system responders. Although many including information maintained by other public regulations are introduced in this guide, each and private organizations. This information is EMS agency should be familiar with, implement, useful; however, APIC cannot guarantee the and comply with state and federal regulatory accuracy, relevance, timeliness, or completeness of requirements. information developed from outside sources. Association for Professionals in Infection Control and Epidemiology 7
Guide to Infection Prevention in Emergency Medical Services Introduction Emergency Medical Services (EMS) system Fire and Emergency Services (2001), are out of responders deliver medical care in many unique date and many changes have taken place since and oftentimes dangerous environments. They they were published. APIC saw a need to develop render care to increasingly mobile populations this Infection Prevention Guide because EMS who potentially have a higher likelihood of having agencies, including public safety and fire, needed an infectious or emerging disease. In addition a comprehensive, easy-to-use guide to serve as to treating accident victims of every nature a resource to develop or enhance their current (vehicular, falls, cuts, burns, and more), they treat knowledge of infection prevention strategies. The the homeless, nursing home patients, trauma information contained in this guide is intended as victims, and the critically ill with multiple diseases a roadmap to develop a comprehensive infection and infections. They have unique concerns prevention program. such as suspect searches, communal living arrangements, and the need to clean and disinfect For the purpose of this guide, all EMS personnel their work equipment. Like many other healthcare will be referred to as EMS system responders. professionals, they face ever-increasing exposures This group encompasses all paid and volunteer to infectious diseases. paramedics and emergency medical technicians (EMTs) on ambulances, first responders, fire Many of the agencies that employ EMS system paramedics and firefighter EMTs, police, and responders are not hospital-based and therefore public safety officers. Although most EMS issues may not have the same knowledge of the are similar, there are some differences among EMS importance of infection prevention as healthcare system responders. Every effort has been made to facilities. Many EMS agencies lack funding address those differences. and have limited staffing. Infection prevention resources exist, but they are not easy to find. This Guide to Infection Prevention in EMS Resources for EMS system responders, such as is intended to assist in keeping EMS system the United States Fire Administration Guide to responders and the patients they care for safe and Managing an Emergency Service Infection Control healthy while reducing their exposure risks. Program (2002) and Infectious Diseases and the 8 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Section 1: Guide Overview Purpose and scope • A lthough compliance with infection prevention standards may seem complex, The purpose of this guide is to provide Emergency this guide will attempt to simplify the Medical Services (EMS) system responders and process and explain why utilizing the their organizations with a practical resource guide is the key to a safe workplace. to infection recognition and prevention in the • EMS leadership must support infection EMS environment. This guide contains current prevention staff and the development information, recommendations, regulations, of infection prevention programs in resources, program examples, and forms to utilize in compliance with laws and regulations. the EMS system responder setting. Leadership support is critical to successful implementation of basic infection Key concepts prevention strategies. • I nfection preventionists (IPs) are healthcare professionals who have special Infection prevention training in infection prevention and Created in hospitals and clinics, infection monitoring. prevention training has by necessity expanded • Many of the principles and practices to include EMS system responders and out- that hospital IPs employ for infection of-hospital emergency medical care agencies. prevention can and should be used Infection prevention programs are designed to in EMS settings, whether it be a fire prevent the transmission of infectious disease department, police agency, or public or agents and to provide a safe work environment for private ambulance company. healthcare personnel and their patients. • EMS system responders are exposed to all manners of infectious diseases and must Infection prevention programs both inside and be trained to recognize them and prevent outside the hospital setting should contain six their spread. major components: • Designated Infection Control Officers (DICOs) are healthcare professionals • dministrative controls A who work for EMS agencies, have special • Engineering controls training, and serve as their agencies’ IP. Federal law requires agencies have a • Work practice controls designated DICO. • Education • The DICO must be up to the challenging • Medical management tasks of keeping current on infection • Vaccine/immunization program prevention topics, conducting ongoing research, and updating procedures and These components will be discussed later in the policies as necessary. guide. Association for Professionals in Infection Control and Epidemiology 9
Guide to Infection Prevention in Emergency Medical Services Although there are articles, references, and This guide contains standards and regulatory guides available on infection prevention in information along with easy-to-follow templates EMS, infection prevention is limited because and forms that can be used to develop an Exposure the expertise and resources are not present in Control Plan and conduct infectious disease many agencies. EMS agencies have known about surveillance, risk assessments, and postexposure bloodborne pathogens for years. However, it has management, as well as monitor compliance. only been in the last 5 to 6 years that articles describing methicillin-resistant Staphylococcus The treatment of exposures and injuries for EMS aureus (MRSA) in ambulances and fire stations system responders has expanded significantly have appeared in fire and EMS literature along with the institution of occupational doctors, with ways to prevent exposures. Two studies found health nurses, safety chiefs, and other DICOs to in the American Journal of Infection Control address oversee personnel health services. These groups the transmission and carriage of MRSA within have developed alliances with local hospitals and the fire department and ambulance environments. county health departments to ensure appropriate The University of Washington Department of postexposure follow-up. They ensure exposures are Environmental and Occupational Health Services handled within accepted treatment guidelines. stated that fire and ambulance personnel have the unique opportunity to acquire and transfer Unfortunately, many departments, counties, and infections from both hospital and community states do not have the funding needed for education sources.1 James V. Rago, PhD, and his team from and training in infection prevention. Some Lewis University and Orland Fire Protection municipal hospitals provide this service and training District, found that 70 percent of ambulances in free to EMS, police, and fire agencies. This guide has the Chicago metropolitan area contained at least included some resources and websites that provide one strain of S. aureus bacteria.2 courses, online training, sample programs, and other information regarding infection prevention. Infection prevention in the public safety sector is challenging. Because the scope of public safety EMS system responders are prepared for members’ duties has expanded, there is an increased disasters and bioterrorism to varying degrees, need to develop awareness and education. but are largely dependent on the available resources and expertise within their EMS In most states, police agencies fall under the agencies. Larger municipal, metropolitan, and Occupational Safety & Health Administration regional systems are often perceived as more (OSHA), Ryan White Notification Law, and prepared to deal with disaster and bioterrorism infection prevention umbrella like other EMS situations. Although there is increased system responders. However, they often have less awareness of bioterrorism incidents throughout training and minimal or no personal protective the United States since September 11, 2001, equipment (PPE) when they respond to a medical no one can be truly prepared for all the hazards emergency or when they encounter a person with they could encounter during a bioterrorism open wounds, blood, or infectious diseases. event. This guide provides an overall view of the types of major biological weapons that might be The National Institute for Occupational Safety encountered, types of PPE, and ways to protect and Health (NIOSH) completed national surveys one’s self and others. that reveal a high incidence of exposures to bloodborne pathogens for paramedics.3 Recent Although EMS system responders acknowledge articles discuss the underreporting of exposures, the importance of protocols for cleaning and the lack of safety equipment, the lack of PPE, and disinfecting equipment, several articles in the lack of training in the use of PPE.3 EMS trade journals cite contamination of fire 10 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services stations, ambulances, and equipment, such as 2 Rago RV, Buhs K, Makarovaite V, Patel E, Pomeroy M, with MRSA.4, 5 OSHA compliance monitoring Yasmine C. Detection and analysis of Staphylococcus aureus requirements are presented later in the guide. isolates found in ambulances in the Chicago metropolitan area. Am J Infect Control 2012 Apr;40(3):201-205. The major goal of this guide is to increase 3 Centers for Disease Control and Prevention. awareness, educate, and provide guidance to Preventing exposures to bloodborne pathogens among EMS system responders who are at risk for paramedics. April 2010. Available at: http://www.cdc. occupational exposure to blood, other potentially gov/niosh/docs/wp-solutions/2010-139/. Accessed infectious materials, infectious diseases, and December 6, 2012. bioterrorism. Standard EMS training curriculum 4 Merlin AM, Wong ML, Pryor PW, Ryan K, Marques- contains information on infection prevention. Baptista A, Perritt R, et al. Presence of methicillin- However, EMS needs more integration with other resistant Staphylococcus aureus on the stethoscopes of EMS community IPs and more efficient communication providers. Prehosp Emerg Care 2009 Jan-Mar;13(1):71-74. networks for information sharing. It is our 5 Roline CE, Rumpecker C, Dunn TM. Can sincere hope that this guide helps ensure a safer methicillin resistant Staphylococcus aureus be found in environment for both EMS system responders and an ambulance fleet? Prehosp Emerg Care 2007 Apr- the patients they care for in the community. June;11(2):241-243. Cited References 1 Roberts MC, Soge OO, No D, Beck NK, Meschke JS. Isolation and characterizations of methicillin- resistant Staphylococcus aureus (MRSA) from fire stations in two northwest fire districts. Am J Infect Control 2011 Jun;39(5):382-389. Association for Professionals in Infection Control and Epidemiology 11
Guide to Infection Prevention in Emergency Medical Services Section 2: Epidemiology and Pathogenesis: Infectious Diseases in EMS Key concepts screening and comparison of treatment effects. Pathogenesis of a disease is the mechanism by • E ffective efforts to eliminate or reduce which the disease is caused. bloodborne and infectious disease exposures and transmission are guided by The Centers for Disease Control and Prevention the epidemiology (causes and distribution) (CDC), through the Ryan White Act, is charged of those diseases. with keeping a list of potentially life-threatening • Communicable diseases can be passed diseases that must be reported by medical facilities from one person to another. Infectious to EMS agencies when one of those diseases is disease can cause illness in a person but is found in a patient transported to their facility. not necessarily communicable. This list reflects diseases that have been around • The current infectious disease burden for many years and diseases that have recently re- for the agency and setting is found emerged (see Table 2.1). EMS agencies should also by conducting an environmental risk be aware of nonreportable diseases that threaten assessment. their workforce. • EMS agencies must ensure all EMS system responders report to work healthy. In the Guideline for Infection Control in They must have a written plan in place Health Care Personnel 1998, the CDC outlining work restriction guidelines when recognized EMS system responders as EMS system responders contract and/or being at risk for acquiring infections from are exposed to an infectious disease. or transmitting infections to patients, • EMS agencies must ensure all EMS other personnel, household members, or system responders have the necessary other community contacts.2 The DICO or immunizations or written proof of personnel health services should arrange for immunity to protect them against the prompt diagnosis of job-related illnesses infectious diseases. and postexposure prophylaxis after job-related exposures. Decisions on work restrictions are based on mode of transmission and Background epidemiology of the disease (Table 2.2). Epidemiology is defined as the study of the Exclusion policies should contain a statement of distribution and determinants of health- authority defining who can exclude personnel related states in specified populations, and and should be designed to encourage personnel the application of this study to control health to report their illnesses or exposures without problems.1 Epidemiology includes outbreak penalizing them with loss of wages, benefits, or investigation, disease surveillance, and job status. 12 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Table 2.1. List of potentially life-threatening infectious diseases to which emergency response employees may be exposed Diseases routinely Diseases caused by agents Diseases routinely transmitted through Diseases routinely potentially used for transmitted by contact or aerosolized airborne transmitted through bioterrorism or biological body fluid exposures means aerosolized droplet means warfare Anthrax, cutaneous Measles (Rubeola virus) Diphtheria These diseases include those (Bacillus anthracis) (Corynebacterium caused by any transmissible diphtheriae) agent included in the HHS Select Agents List Hepatitis B (HBV) Tuberculosis Novel influenza A viruses (Mycobacterium as defined by the Council tuberculosis)—infectious of State and Territorial pulmonary or laryngeal Epidemiologists (CSTE) disease; or extrapulmonary (draining lesion) Hepatitis C (HCV) Varicella disease (Varicella Meningococcal disease zoster virus)—chickenpox, (Neisseria meningitidis) disseminated zoster Human immunodeficiency Mumps (Mumps virus) virus (HIV) Rabies (Rabies virus) Pertussis (Bordetella pertussis) Vaccinia (Vaccinia virus) Plague, pneumonic (Yersinia pestis) Viral hemorrhagic fevers Rubella (German measles; (Lassa, Marburg, Ebola, Rubella virus) Crimean-Congo, and other viruses yet to be identified) SARS-CoV Adapted from National Institute for Occupational Safety and Health. List of potential life-threatening diseases. 3 Table 2.2. Summary of suggested work restrictions for healthcare personnel exposed to or infected with infectious diseases of importance in healthcare settings, in the absence of state and local regulations Disease/problem Work restriction Duration Category Conjunctivitis Restrict from patient contact Until discharge ceases II and contact with the patient’s environment Cytomegalovirus infections No restriction I Diarrheal diseases I Acute stage (diarrhea with Restrict from patient contact, contact Until symptoms resolve IB other symptoms) with the patient's environment, or food handling (continued) Association for Professionals in Infection Control and Epidemiology 13
Guide to Infection Prevention in Emergency Medical Services Table 2.2. Summary of suggested work restrictions for healthcare personnel exposed to or infected with infectious diseases of importance in healthcare settings, in the absence of state and local regulations, continued Disease/problem Work restriction Duration Category Convalescent stage, Restrict from care of high-risk Until symptoms resolve; IB Salmonella spp. patients consult with local and state health authorities regarding need for negative stool cultures Diphtheria Exclude from duty Until antimicrobial therapy IB completed and 2 cultures obtained 24 hours apart are negative Enteroviral infections Restrict from care of infants, Until symptoms resolve II neonates, and immunocompromised patients and their environments Hepatitis A Restrict from patient contact, contact Until 7 days after onset of IB with patient’s environment, and food jaundice handling Hepatitis B Personnel with acute or No restriction; refer to state chronic hepatitis B surface regulations; Standard Precautions antigemia who do not should always be observed perform exposure-prone procedures Personnel with acute or Do not perform exposure-prone Until hepatitis B e antigen is II chronic hepatitis B e anti- invasive procedures until counsel negative genemia who perform from an expert review panel has been exposure-prone procedures sought; panel should review and recommend procedures the worker can perform, taking into account specific procedure as well as skill and technique of worker; refer to state regulations Hepatitis C Restrict only from Class III procedures II Herpes simplex Genital No restriction II Hands (herpetic whitlow) Restrict from patient contact and contact Until lesions heal IA with the patient’s environment Orofacial Evaluate for need to restrict from care of high-risk patients Human immunodeficiency Do not perform exposure-prone virus invasive procedures until counsel from an expert review panel has been sought; panel should review and recommend procedures the worker can perform, taking into account specific procedure as well as skill and technique of the worker; standard precautions should always be observed; refer to state regulations (continued) 14 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Table 2.2. Summary of suggested work restrictions for healthcare personnel exposed to or infected with infectious diseases of importance in healthcare settings, in the absence of state and local regulations, continued Disease/problem Work restriction Duration Category Measles Active Exclude from duty Until 7 days after the rash IA appears Postexposure (susceptible Exclude from duty From 5th day after 1st IB personnel) exposure through 21st day after last exposure and/or 4 days after rash appears Meningococcal infections Exclude from duty Until 24 hours after start of IA effective therapy Mumps Active Exclude from duty Until 9 days after onset of IB parotitis Postexposure (susceptible Exclude from duty From 12th day after 1st II personnel) exposure through 26th day after last exposure or until 9 days after onset of parotitis Pertussis Active Exclude from duty From beginning of catarrhal IB stage through 3rd wk after onset paroxysms or until 5 days after start of effective antimicrobial therapy Postexposure No restriction; prophylaxis I (asymptomatic personnel) recommended Postexposure Exclude from duty Until 5 days after start of IB (symptomatic personnel) effective antimicrobial therapy Rubella Active Exclude from duty Until 5 days after rash appears IA Postexposure (susceptible Exclude from duty From 7th day after 1st IB personnel) exposure through 21st day after last exposure Scabies Restrict from patient contact Until cleared by medical IB evaluation Staphylococcus aureus Infection Active, draining skin Restrict from contact with patients and Until lesions have resolved IB lesions patient’s environment or food handling Carrier state No restriction, unless personnel IB are epidemiologically linked to transmission of the organism (continued) Association for Professionals in Infection Control and Epidemiology 15
Guide to Infection Prevention in Emergency Medical Services Table 2.2. Summary of suggested work restrictions for healthcare personnel exposed to or infected with infectious diseases of importance in healthcare settings, in the absence of state and local regulations, continued Disease/problem Work restriction Duration Category Streptococcal infection, Restrict from patient care, contact with Until 24 hours after adequate IB group A patient’s environment, or food handling treatment started Tuberculosis Active disease Exclude from duty Until proved noninfectious IA PPD converter No restriction IA Varicella Active Exclude from duty Until all lesions dry and crust IA Postexposure (susceptible Exclude from duty From 10th day after 1st IA Personnel) exposure through 21st day (28th day if VZIG given) after last exposure Zoster Localized, in healthy Cover lesions; restrict from care of Until all lesions dry and crust II person high-risk patients† Generalized or localized in Restrict from patient contact Until all lesions dry and crust IB immunosuppressed person Postexposure (susceptible Restrict from patient contact From 10th day after 1st IA personnel) exposure through 21st day (28th day if VZIG given) after last day exposure or, if Varicella occurs, until all lesions dry and crust Viral respiratory infections, Consider excluding from the care of Until acute symptoms resolve IB acute febrile high-risk patients‡ or contact with their environment during community outbreak of RSV and influenza *Unless epidemiologically linked to transmission of infection †Those susceptible to varicella and who are at increased risk of complications of varicella, such as neonates and immuno- compromised persons of any age. ‡High-risk patients as defined by the ACIP for complications of influenza. As in previous CDC guidelines, each recommendation is categorized on the basis of existing scientific data, theoretic rationale, applicability, and potential economic impact. The system for categorizing recommendations is as follows: Category IA - Strongly recommended for all hospitals and strongly supported by well-designed experimental or epide- miologic studies. Category IB - Strongly recommended for all hospitals and reviewed as effective by experts in the field and a consensus of Hospital Infection Control Practices Advisory Committee members on the basis of strong rationale and suggestive evidence, even though definitive scientific studies have not been done. Category II - Suggested for implementation in many hospitals. Recommendations may be supported by suggestive clini- cal or epidemiologic studies, a strong theoretic rationale, or definitive studies applicable to some but not all hospitals. No recommendation; unresolved issue - Practices for which insufficient evidence or consensus regarding efficacy exists. Source: Bolyard EA, Tablan OC, Williams WW, Pearson ML, Shapiro CN,Deitchman SD, et al. Guideline for infection control in healthcare personnel, 1998. Centers for Disease Control and Prevention. Available at: www.cdc.gov/hicpac/ pdf/InfectControl98.pdf 16 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Immunization programs resistant S. aureus (MRSA) is a strain of staph bacteria that is resistant to ß-lactam antibiotics. Ensuring that personnel are immunized against vaccine-preventable diseases is an essential part Until the late 1990s MRSA was predominately of successful personnel health programs, and found in hospitals. However, starting in the OSHA is enforcing the CDC immunization late 1990s, MRSA infections were increasingly guidelines (Table 2.3). Immunization can prevent found in populations with no known healthcare- transmission of vaccine-preventable diseases and associated risks for acquisition.5 These cases were eliminate unnecessary work restriction. Prevention labeled community-acquired MRSA (CA-MRSA). of illness through comprehensive personnel According to the International Association of Fire immunization programs is far more cost-effective Fighters, MRSA is considered a serious threat to than case management, outbreak control, sick EMS system responders.6 Because EMS system leave, and replacement costs. responders bridge the community and healthcare settings, they are at high risk for contracting and Decisions about vaccines to include in transmitting MRSA. immunization programs have been made by considering the following: Although hospital-associated MRSA infections are tracked, most EMS agencies do not have the (a) The likelihood of personnel exposure processes in place to track cases of CA-MRSA. to vaccine-preventable diseases and the In order to implement interventions to reduce potential consequences of not vaccinating or eliminate MRSA, total number of cases each personnel year should be tracked along with all associated (b) The nature of employment (type medical costs. of contact with patients and their environment) Strategies to prevent (c) The characteristics of the patient transmission of MRSA and population within the healthcare organization other infectious diseases Documentation shows MRSA transmission both (d) Nationally accepted standards such directly from infected and colonized patients as NFPA 1581 (NFPA 1581, Standard and indirectly via contaminated equipment, on Fire Department Infection Control supplies, and environmental surfaces. Standard Program) and 1582 (Standard on Precautions is the first step in prevention, as is Comprehensive Occupational Medical identification of common transmission routes. Program for Fire Departments). When the sources of transmission are identified, infection prevention staff or the DICO should Example of epidemiology, implement a series of focused interventions pathogenesis, and transmission including the following: Staphylococcus aureus is found on the skin of humans • E ducation in infection prevention as part of our normal body flora. It is estimated that nasal colonization in the general U.S. adult • Proper and frequent use of disinfectants population is 25 to 30 percent.4 S. aureus from nasal • Hand hygiene and the appropriate use of colonization can be transferred to skin and other gloves body areas. An infection occurs when a breach in • Replacement of cloth surfaces with hard the skin allows staph bacteria to enter. Methicillin- surfaces Association for Professionals in Infection Control and Epidemiology 17
18 Association for Professionals in Infection Control and Epidemiology Guide to Infection Prevention in Emergency Medical Services Table 2.3. Immunobiologics and schedules and immunizing agents strongly recommended for healthcare personnel Primary booster dose Major precautions and Generic name Indications Special considerations schedule contraindications Hepatitis B recombinant Two doses IM in the Healthcare personnel at risk of No apparent adverse effects No therapeutic or adverse effects vaccine deltoid muscle 4 weeks exposure to blood and body fluids to developing fetuses, not on HBV-infected persons; cost- apart; third dose 5 contraindicated in pregnancy; effectiveness of prevaccination months after second; history of anaphylactic reaction to screening for susceptibility booster doses not common baker’s yeast to HBV depends on costs of necessary vaccination and antibody testing and prevalence of immunity in the group of potential vaccines; healthcare personnel who have ongoing contact with patients or blood should be tested 1–2 months after completing the vaccinations series to determine serologic response Influenza vaccine Annual single-dose Healthcare personnel with contact History of anaphylactic No evidence of maternal or fetal (inactivated whole or vaccination IM with with high-risk patients or working hypersensitivity after egg ingestion risk when vaccine was given to split virus) current (either whole or in chronic care facilities; personnel pregnant women with underlying split-virus) vaccine with high-risk medical conditions conditions that render them at and/or ≥65 years high risk for serious influenza complications Measles live-virus One dose SC; second Healthcare personnel born in or Pregnancy; immunocompromised* MMR is the vaccine of choice vaccine dose at least 1 month after 1957 without documentation state; (including HIV- if recipients are also likely to later of (a) receipt of two doses of infected) persons with severe be susceptible to rubella and/ live vaccine on or after their first immunosuppression) history of or mumps; persons vaccinated birthday, (b) physician-diagnosed anaphylactic reactions after gelatin between 1963 and 1967 with (a) measles, or (c) laboratory evidence ingestions or receipt of neomycin; a killed measles vaccine alone, of immunity; vaccine should or recent receipt of immune (b) killed vaccine followed by be considered for all personnel, globulin live vaccine, or (c) a vaccine including those born before 1957, of unknown type should be who have no proof of immunity revaccinated with two doses of live measles vaccine
Table 2.3. Immunobiologics and schedules and immunizing agents strongly recommended for healthcare personnel, continued Primary booster dose Major precautions and Generic name Indications Special considerations schedule contraindications Mumps live-virus One dose SC; no booster Healthcare personnel believed to Pregnancy; immunocompromised* Women pregnant when vaccinated vaccine be susceptible can be vaccinated; state; history of anaphylactic or who become pregnant within 3 adults born before 1957 can be reactions after gelatin ingestions or months of vaccination should be considered immune receipt of neomycin counseled on the theoretic risks to the fetus, the risk of rubella vaccine-associated malformations in these women is negligible; MMR is the vaccine of choice if recipients are also likely to be Association for Professionals in Infection Control and Epidemiology susceptible to measles or mumps Rubella live- One dose SC; Healthcare personnel, both Pregnancy; immunocompromised* Women pregnant when vaccinated virus vaccine no booster male and female, who lack state; history of anaphylactic or who become pregnant within 3 Guide to Infection Prevention in Emergency Medical Services documentation of receipt of live reaction after receipt of neomycin months of vaccination should be vaccine on or after their first counseled on theoretic risks to the birthday, or of laboratory evidence fetus, the risk of rubella vaccine- of immunity; adults born before associated malformations in these 1957 can be considered immune, women in negligible; MMR is except women of childbearing age the vaccine of choice if recipients are also likely to be susceptible to measles or mumps Varicella zoster live-virus Two 0.5 mL doses SC, Healthcare personnel without Pregnancy, immunocompromised* Because 71%–93% of persons vaccine 4–8 weeks apart if ≥13 reliable history of varicella or state, history of anaphylactic without a history of varicella are years laboratory evidence of varicella reaction after receipt of neomycin immune, serologic testing before immunity or gelatin; salicylate use should vaccination may be cost-effective be avoided for 6 weeks after vaccination IM, Intramuscular; SC, subcutaneously. *Persons immunocompromised because of immune deficiencies, HIV infection, leukemia, lymphoma, generalized malignancy, or immunosuppressive therapy with corticosteroids, alkylating drugs, antimetabolites, or radiation. Source: Bolyard EA, Tablan OC, Williams WW, Pearson ML, Shapiro CN,Deitchman SD, et al. Guideline for infection control in healthcare personnel, 1998. Centers for Disease Control and Prevention. Available at: www.cdc.gov/hicpac/pdf/InfectControl98.pdf. Accessed January 24, 2013. 19
Guide to Infection Prevention in Emergency Medical Services • C onfinement of turnout gear to work Contact Precautions for MRSA areas patients • Station wear kept at the station and laundered after use. In addition to Standard Precautions described, CDC recommends using Contact Precautions if In addition, EMS system responders should use a patient is known to be colonized with MRSA Standard Precautions as described below in Table or has an active MRSA infection. In general, 2.4 to prevent transmission of MRSA and other Contact Precautions will be applied once the multidrug-resistant organisms. patient is admitted to the hospital. However, Table 2.4. Recommendations for application of standard precautions for the care of all patients in all healthcare settings7 Component Recommendations Hand hygiene After touching blood, body fluids, secretions, excretions, contaminated items; immediately after removing gloves; between patient contacts Personal protective equipment (PPE) Gloves For touching blood, body fluids, secretions, excretions, contaminated items; for touching mucous membranes and nonintact skin Gown During procedures and patient-care activities when contact of clothing/exposed skin with blood/body fluids, secretions, and excretions is anticipated Mask, eye protection (goggles), face shield* During procedures and patient-care activities likely to generate splashes or sprays of blood, body fluids, secretions, especially suctioning, endotracheal intubation Soiled patient-care equipment Handle in a manner that prevents transfer of microorganisms to others and to the environment; wear gloves if visibly contaminated; perform hand hygiene Environmental control Develop procedures for routine care, cleaning, and disinfection of environmental surfaces, especially frequently touched surfaces in patient-care areas Textiles and laundry Handle in a manner that prevents transfer of microorganisms to others and to the environment Needles and other sharps Do not recap, bend, break, or hand-manipulate used needles; if recapping is required, use a one-handed scoop technique only; use safety features when available; place used sharps in puncture-resistant container Patient resuscitation Use mouthpiece, resuscitation bag, other ventilation devices to prevent contact with mouth and oral secretions Patient placement Prioritize for single-patient room if patient is at increased risk of transmission, is likely to contaminate the environment, does not maintain appropriate hygiene, or is at increased risk of acquiring infection or developing adverse outcome following infection (continued) 20 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Table 2.4. Recommendations for application of standard precautions for the care of all patients in all healthcare settings7, continued Component Recommendations Respiratory hygiene/cough etiquette Instruct symptomatic persons to cover mouth/nose when sneezing/ (source containment of infectious respiratory coughing; use tissues and dispose in no-touch receptacle; observe secretions in symptomatic patients, beginning hand hygiene after soiling of hands with respiratory secretions; wear at initial point of encounter; e.g., triage and surgical mask if tolerated or maintain spatial separation, >3 feet if reception areas in emergency departments and possible. physician offices) * During aerosol-generating procedures on patients with suspected or proven infections transmitted by respiratory aero- sols (e.g., SARS), wear a fit-tested N95 or higher respirator in addition to gloves, gown, and face/eye protection. As part of respiratory etiquette, EMS system responders are advised to wear an approved mask or respirator and eye protection when examining and caring for patients with signs and symptoms of a respiratory infection. More detailed information on masks is provided in the Work Practice Controls and Personal Protective Equipment (PPE) section later in the guide. EMS system responders can adapt elements controlling body fluids. Table 2.5 describes the of these precautions to prevent contracting or basic components of Contact Precautions with transmitting MRSA prior to the patient’s arrival some adaptions made for the EMS to the hospital, particularly in cases in which environment. patients have draining wounds or difficulty Table 2.5. Basic components of Contact Precautions Component Recommendations Patient transport Ensure infected or colonized areas of the patient’s body are covered and contained; don clean PPE and perform hand hygiene prior to transporting patient and again when handling the patient upon arrival to transport destination Gloves For touching intact skin or surfaces and articles in close proximity to the patient Gown For interactions with the patient or in the patient care environment that may result in contamination of clothing or environment outside of the area of patient care; gowns should be disposed and hand hygiene performed prior to leaving the patient care environment, ensuring that clothing and skin do not come in contact with contaminated surfaces Patient care equipment When possible, use dedicated noncritical patient care equipment; ensure any nondedicated equipment is properly cleaned and disinfected before use with another patient Environmental control Develop procedures to ensure cleaning and disinfection of high-touch surfaces and areas in close proximity to patient on Contact Precautions Patient placement (Upon arrival at hospital) Single patient room, if available, or cohorting with other patients who have MRSA or who have low risk of acquiring or suffering adverse effects of a MRSA infection Adapted from: Siegel JD, Rhinehart E, Jackson M, Chiarello L, and the Healthcare Infection Control Practices Advisory Committee. Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings, 2007. Available at: http://www.cdc.gov/hicpac/2007IP/2007isolationPrecautions.html. Accessed January 24, 2013. Association for Professionals in Infection Control and Epidemiology 21
Guide to Infection Prevention in Emergency Medical Services Cited References 7 The CDC Healthcare Infection Control Practices Advisory Committee. 2007 Guideline for Isolation 1 Centers for Disease Control and Prevention. Precautions: Preventing Transmission of Infectious Agents An introduction to epidemiology. 2004. Available in Healthcare Settings. Available at: http://www.cdc. at: www.cdc.gov/excite/classroom/intro_epi.htm. gov/hicpac/2007IP/2007isolationPrecautions.html. Accessed January 24, 2013. Accessed January 24, 2013. 2 Sepkowitz KA. Occupationally acquired infections in health care workers. Part I and II. Ann Intern Med Additional Resources 1996;125:826-834/917-928. Centers for Disease Control and Prevention. List of 3 Implementation of Section 2695 (42 USC 300ff- potentially life-threatening infectious diseases to which 131) of Public Law 111-87: Infectious Diseases and emergency response employees may be exposed. Federal Circumstances Relevant to Notification Requirements. Register Dec 2 2011;76(212). Federal Register Nov 2 2011;76(212). Available at: http://www.cdc.gov/niosh/topics/ryanwhite/pdfs/ NFPA 1581, Standard on Fire Department Infection FRN11-2-2011GPO.pdf. Accessed January 24, 2013. Control Program, 2005. 4 Centers for Disease Control and Prevention. MRSA NFPA 1582, Standard on Comprehensive and the workplace. 2011. Available at: www.cdc.gov/ Occupational Medical Program for Fire Departments, niosh/topics/mrsa. Accessed January 24, 2013. 2007. 5 Aureden K, Arias K, Burns L, Creen, C, Hickok J, Ryan White HIV/AIDS treatment extension act of Moody J, et al. Guide to the elimination of methicillin- 2009. Available at: http://www.cdc.gov/niosh/topics/ resistant Staphylococcus aureus (MRSA) transmission ryanwhite/. Accessed December 13, 2012. in hospital settings, 2nd ed. Washington, DC: Roche, 2010; 8. CDC Select Agent Program. Available at: http://www. cdc.gov/phpr/documents/DSAT_brochure_July2011. 6 Williams D. Danger in the station: drug resistant pdf. Accessed December 13, 2012. infections. Fire Engineering 2006;I59:69-74. 22 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Section 3: Risk Factors/Risk Assessment in EMS Purpose name a few. EMS system responders are routinely exposed to situations that threaten their personal Awareness of hazards is an important part of safety, including exposures to infectious diseases, protecting EMS system responders. Agencies hazardous materials, and sharps-related injuries. can perform a hazard risk assessment to obtain a They may encounter combative patients, patients baseline incidence, prevalence, and transmission of with infectious diseases, traumatic injuries, and hazards. These include exposure to communicable exposure to chemical, biological, radiological diseases, hazardous materials, and sharps-related agents, and exposures related to bioterrorism. injuries. The hazard risk assessment guides development of a surveillance, prevention, and There are many federal, state, and local practice infection control program. standards, resources, and expert guidance to assist agencies with infection prevention plans. Key concepts Agencies must also develop a tracking system to monitor exposure and injury trends. Monitoring • P ast and current agency-specific trends over time will show whether incidences surveillance data is the focus of the risk of exposures and sharps-related injury rates are assessment. decreasing or whether additional actions need to • Exposure and injury surveillance data be taken if rates are increasing. Comparison with includes demographic, geographic, and baseline measurements and analysis will determine published EMS/Fire/Public Safety data the need for an intervention and determine the on risk. appropriate intervention. Continued monitoring • R isk assessment should be continuously is needed to reassess the effectiveness of the revised or updated when there is a change interventions. based on ongoing surveillance, when populations change, or when additional If available, past and current agency surveillance risks are identified. data is the core of the risk assessment. • Information from the risk assessment Agencies can obtain relevant infectious disease drives education and improvement surveillance data from local and state public processes. Epidemiology is the foundation health departments. Agencies should monitor of the process. community and population-specific risk factors and epidemiology for the following diseases: Background • uberculosis T EMS system responders face a wide variety of • HIV/AIDS serious hazards due to the unpredictable nature of their jobs. There are exposure and injury risks at • Hepatitis C motor vehicle accidents, fires, hazardous materials • Influenza (hazmat) incidents, and mass casualty incidents to • MRSA Association for Professionals in Infection Control and Epidemiology 23
Guide to Infection Prevention in Emergency Medical Services • O ther emerging multidrug-resistant Infectious diseases and sharps- organisms (MDROs) related injuries risk assessment • O ther diseases on the CDC list of basics reportable diseases (see Table 2.1) EMS system responders should use Standard In addition, each DICO should be aware of their Precautions for all patients. They should use state’s specific regulations (i.e., California 5199) additional PPE based on the risks they identify for disease monitoring and reporting. from the information they receive from dispatch or from their assessment when they arrive on the scene. Some agencies have the ability to identify Infectious disease and sharps patients with confirmed or suspected infectious injury risk factors diseases in dispatch information. However, given General risk factors for infectious diseases and the mobile nature of society, agencies must be aware sharps-related injuries are well documented in that the person at the address may not be the same medical literature. Known risk factors include, but as in agency records. EMS agencies must develop are not limited to: relationships with hospital IPs and local public health departments to develop a system for reporting and treating personnel with exposures. The ability to • E xposure to patients with chronic diseases track infectious disease exposures and sharps-related (HIV, hepatitis B and C) injuries is essential for risk assessment. Standardized • E xposure to blood and other potentially processes for capturing relevant data ensure that infectious fluids statistical evaluation is relevant and can be compared • E xposure to patients with infectious over time. The following is an example to illustrate diseases (MRSA, meningitis, influenza) risk assessment basics. • F ailure to use engineering controls such as self-sheathing IV catheters and needleless The EMS exposure risk assessment requires the systems person responsible for tracking exposures (i.e., DICO, occupational health RN, IP) to do the following: • Failure to use appropriate sharps containers • H igh-risk procedures such as intubation, Example 3.1. Utilizing exposure surveillance IV starts, and bandaging data for infectious diseases, airborne, bloodborne, • Noncompliance with Standard Precautions hazmat, and sharps-related exposures when a risk • Poor hand washing techniques assessment is conducted • F aulty, defective, or improperly used Description of exposures and action required are equipment summarized in the table below. • Lack of preventative immunizations EXPOSURE ACTION • F ailure to properly decontaminate DESCRIPTION REQUIRED equipment and other work surfaces Exposure of open Clean exposed area; • Poorly lit work area skin, cuts, or breaks or if in the mouth, rinse • H azardous work areas including mucous membranes, and spit; flush eyes as hazardous material or fire responses such as eyes, nose, appropriate. Provide • C ombative patients with obvious blood or mouth, to blood first aid if needed. Call exposure or body fluids. This your DICO. • I nappropriate disposal of contaminated includes needlesticks sharps and human bites. 24 Association for Professionals in Infection Control and Epidemiology
Guide to Infection Prevention in Emergency Medical Services Example 3.1. Annual Summary of Reported EMS Exposures Jan. Feb. Mar. Apr. May Jun. Jul. Aug. Sept. Oct. Nov. Dec. Total No. of exposures 1 0 2 4 4 4 2 4 2 7 2 3 35 Infectious 0 0 1 2 2 4 1 0 1 0 1 2 14 Airborne Hazmat 1 0 0 0 0 0 0 4 0 2 0 0 7 Needlestick 0 0 0 1 0 0 0 0 0 0 0 0 1 Nonintact skin 0 0 0 1 0 0 1 0 1 2 1 0 6 Bloodborne Mucous 0 0 1 0 2 0 0 0 0 3 0 1 7 membrane • E stablish baseline incidence and/or • E nsure employees have annual exposure prevalence of exposures and injuries control plan training that allows enough (agencies should look for the incidence time for feedback and questions. rate tied to patient contacts; i.e., exposures per 1,000 patient contacts). In the example provided, using infectious disease • Identify high-risk employee practices exposure surveillance data for the infectious or stations based on incident rates and disease assessment of the EMS system responders identify clusters to determine if additional who had a reported exposure (number = 6), three interventions may be needed. were diagnosed and treated for MRSA. Since • Evaluate infectious disease transmission beginning to track MRSA-reported exposures, over time to characterize station-specific reporting has increased, although the total number and disease-specific prevalence or of actual patients with MRSA is unknown because transmission rates. that information is not always given to the EMS system responder. The DICO investigated all • Track employee absenteeism to detect reported MRSA-related exposure reports and subtle variances in sick leave associated determined only six patients had confirmed with specific stations, or shifts, to serve MRSA. Because of the Health Insurance as an early sentinel to possible infectious Portability and Accountability Act (HIPAA) disease implications. constraints, not all crews receive confidential • Establish rates and ensure compliance patient medical information regarding their with Standard Precautions and PPE use. potential infectious disease status as part of the call • Focus data-driven interventions on stations/ read back from the dispatch center and hospitals employees with high exposure or injury rates. do not always report back to the EMS system • Obtain employee input to improve responders. infection control policies and procedures to maximize support and participation. EMS system responders submit an exposure report • Identify gaps in knowledge for targeted and document the disease they were exposed educational interventions. to during patient care (see Example 3.2). EMS Example 3.2. MRSA exposure report Year 2003 2004 2005 2006 2007 2008 2009 2010 Number of Reported MRSA Exposures 1 5 4 9 0 12 21 24 Association for Professionals in Infection Control and Epidemiology 25
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