GENESIS Biomed and GENESIS Ventures - Corporate Presentation March 2020
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GENESIS Biomed and GENESIS Ventures Corporate Presentation March 2020 Please contact us at: Baldiri Reixac 4, 08028 Barcelona Velázquez 25, 2º A, 28001 Madrid contact@genesis-biomed.com +34 93 403 58 53 GENESIS Biomed - Corporate Presentation 1
01 Corporate Presentation of GENESIS Biomed Who are we? GENESIS Biomed is a consultancy firm in the biomedical healthcare sector specialized in providing consulting services to spin-off and start-up companies, entrepreneurs and research centers. Based in our expertise we help entrepreneurs and researchers to shape their business plan and we support them in the private fundraising process. We have raised >45 M€ in the last years. We are Associate Partner at EIT Health and we are currently working in 7 EIT Health projects with TOP EU institutions. Our expertise domains are biopharmaceutical, biotechnological, medical devices, in vitro diagnostic, nutraceutical and cosmetic. With more than 20 years of expertise in the healthcare sector, we are born in May 2017 and we are located in the Barcelona Science Park. In addition, the company owns GENESIS Ventures, a new fund sized in 2,0 M€ that invests in early stage research projects in the biomedical field, with the aim to accelerate their development and reach key value milestones to found the company and attract a first round of investment from other venture funds. GENESIS Biomed - Corporate Presentation 3
01 Corporate Presentation of GENESIS Biomed Our locations: Barcelona and Madrid We are glad to announce that in September 2019 we have open our new offices located at Velázquez 25, Madrid. Located in the real center of Madrid, our new offices will allow us to work closely with the clients we have in Madrid area. In the coming weeks we will hire a manager and two consultants for our Madrid Office. GENESIS Biomed HQ We will keep our Barcelona staff in 10 Madrid Office members, and GENESIS CEO will be Barcelona Science Park, Tower I Calle de Velázquez 25, 2º A working part time in both offices. Baldiri Reixac 4 28001 Madrid 08028 Barcelona GENESIS Biomed - Corporate Presentation 4
01 Corporate Presentation of GENESIS Biomed Our portfolio of services 1 Business Plan 2 Private Fundraising 3 Interim CEO Preparation of business plans for spin-off or Definition of the fundraising strategy. Selection For those start-up companies with an start-up companies, taking into account market, of private investors among a wide personal incomplete team. Serving as CEO and leading positioning, regulatory, development, IP, team network and assistance in the fundraising and the Project until identifying and hiring a full- and financials. negotiation. time CEO. 4 Strategic follow-up and supervision of current projects – For those companies developing a project after a first capital round, continuous supervision and support in the strategic decision making of the company, serving as Board observer if needed. 5 Market Analysis 6 Regulatory and Development Plan 7 Partners in EIT Health and H2020 Preparation of market and competitors analysis Preparation of regulatory roadmaps including Participation in European consortiums as using robust databases, knowledge regulatory strategy and development plans for proactive partners, leading the business, management tools and fieldwork (interviews biopharma, medtech, diagnostic, nutra and regulatory and commercial work packages, in and focus groups). cosmetic. EIT Health, H2020, FTI and SME-2 8 Business Development 9 Strategic Plan 10 Training & Academy For companies and research centres. Preparation of strategic plans for research For hospitals and research centres. In-licensing and out-licensing activities. Well centres and companies, including Provide general knowledge in biomedical established BD process built in the last 10 years internal/external diagnostic, vision, strategic entrepreneurship and technology transfer to + wide network of contacts. objectives and action plan. researchers and institutions GENESIS Biomed - Corporate Presentation 5
01 Corporate Presentation of GENESIS Biomed Our value proposition in fundraising projects: from the Scientific case to the Investment case Investment case In the projects related to fundraising, we always start from the Scientific Case, always excellent that comes from the Research Group. Business case We convert it into a Business Case, that is containing all the aspects to be considered in a Business Plan. Finally, creating a team between GENESIS Biomed and the Research Group, we start a process that helps the investors to Scientific create their Investment case that provides them support in the case decision making. GENESIS Biomed - Corporate Presentation 6
01 Corporate Presentation of GENESIS Biomed Participation in EU projects as proactive partners 1 Preparation of Business Plan and Design of Business Model 2 Market research and market analysis including fieldwork 3 Implantation Plan and Market Access Plan 4 Commercialization and Exploitation Plan 5 Regulatory roadmap and Regulatory development activities 6 Business Development for Licensing / M&A Currently working in 12 EU funded projects. We become very proactive partners in the preparation of the proposal and in the hearings. We are also a high proactive business partner during the development of the project. GENESIS Biomed - Corporate Presentation 7
01 Corporate Presentation of GENESIS Biomed GENESIS Biomed becomes EIT Health Associate Partner Innovation Pillar Acceleration Pillar GENESIS Biomed will apply to the appropriate GENESIS Biomed can contribute to take part as a calls in which our expertise can contribute for consortium member in Innovation by Ideas or the Pillar, such as bootcamps, Market Coach Innovation by Design projects. Network, Investors network, Crowdfunding platform, Catapult, etc. We have become Associate The main tasks to be carried out will be: Partner • Business plans at EIT Health • Business coaching on May 14th 2018 • Commercialization Campus Pillar • Business development • Preparation of WP0 We can also contribute in Campus projects by We have also become • Etc preparing Sustainability Plans or Bootcamps. Members of the Spanish Management Board at EIT Health GENESIS Biomed - Corporate Presentation 8
01 Corporate Presentation of GENESIS Biomed EIT Health, the main biomedical European network with TOP companies and institutions Our presence in EIT Health as Associate partner allows us to collaborate with TOP international institutions In the last months we have started 8 international projects GENESIS Biomed - Corporate Presentation 9
01 Corporate Presentation of GENESIS Biomed Our current client portfolio (1/3) Spin-off and start-up Big & mid-size GENESIS Biomed - Corporate Presentation 10
01 Corporate Presentation of GENESIS Biomed Our current client portfolio (2/3) Academia & Research GENESIS Biomed - Corporate Presentation 11
01 Corporate Presentation of GENESIS Biomed Our current client portfolio (3/3) Healthcare Investors Institutional GENESIS Biomed - Corporate Presentation 12
01 Corporate Presentation of GENESIS Biomed GENESIS team @ Barcelona Office: 11 very committed and passionate people Josep Lluís Falcó Natalia de la Figuera Jordi Ortiz Carles Taulé Berta Borràs Mireia Samitier Managing partner & CEO Managing partner & COO Senior Consultant Consultant Consultant Consultant Chemist PhD, MBA Chemist PhD, PMP® Chemist Pharmacist Biotech. and Biochemist Biologist Gisela Gallego Anna Miró Alberto Rodríguez Mariona Costa Teresa Bau Consultant Consultant Consultant trainee Consultant trainee Comms Manager Biotechnologist Biomedical Sciences Biotechnologist Biotechnologist Journalist & Digital MKT GENESIS Biomed - Corporate Presentation 13
01 Corporate Presentation of GENESIS Biomed A highly committed team Josep Lluís Falcó. Doctor in Chemistry (Institut Químic de Sarrià) and MBA (Universitat de Barcelona). Josep Lluís has 21 years of experience in the biomedical sector. He has worked for big pharma companies (Sanofi), mid-size pharmas (Ferrer Grupo), small biotechs (Hospital spin-off), Tech Transfer Offices (Fundació Bosch i Gimpera) and Consulting firms (Antares Consulting and Asphalion). He has also been associate professor at IQS. His experience is based in Healthcare Strategy, Technology Transfer, Fundraising of start-up companies, Business Development, Marketing, Market Access, Reimbursement and Regulatory Affairs. Josep Lluís has founded 4 companies. He currently serves as board member for 5 start-up companies and he is mentor of several entrepreneurs. In addition in the last 5 years he has been involved in 11 private fundraising processes and he has contributed to raise 42 million euros for his clients. The projects in which Josep Lluís has been involved are based in small chemical entities, biologicals, diverse medical devices, in vitro diagnostics, nutraceuticals and cosmetics. The therapeutic areas where he has recently worked are Oncology, Central Nervous System, Cardiovascular, Ophthalmology, Orthopedics, Traumatology, HIV, Microbiome, Antibacterials and Immunomodulation. He has global knowledge of drug/device development, having worked in Discovery, Preclinical and Clinical phases, Marketing and Post- Marketing. Josep Lluís Falcó Managing partner and CEO He takes part of programs such as Caixa Impulse and EIT Health programs, participating as reviewer, mentor and professor. jlfalco@genesis-biomed.com The entrepreneurial spirit runs through his veins. He has founded GENESIS Biomed to help other entrepreneurs and research centers in their current projects. GENESIS Biomed - Corporate Presentation 14
01 Corporate Presentation of GENESIS Biomed A highly committed team Natalia de la Figuera. PhD in Chemistry, Master in Project Management, PMP® Natalia has developed her professional experience both in academic (CSIC Madrid and Barcelona) and in the pharmaceutical industry: big pharma (Fresenius Kabi, Sanofi, Lilly, Merck-Serono), mid-size (Almirall, Palau Pharma) and start-ups (Ojer Pharma, ImmunNovative Developments, Enantia). She has worked in different positions in areas as project management, regulatory affairs, R & D and Quality among others. The main therapeutic areas on which she has been involved were oncology, central nervous system, anti-inflammatory, antibacterial, autoimmune diseases and cardiovascular. From 2015 she has been focused mainly in project management, broadening her knowledge on economic- administrative monitoring and controlling, changes request and dissemination results of projects. During her last job in the FSJD (Fundació Sant Joan de Déu) she was involved on public funding projects, some of them collaboratives, allowing her to acknowledge another health environment. Natalia de la Figuera She joins GENESIS Biomed in April 2019. She is a passionate of improving health and quality life for patients Managing partner and COO ndelafiguera@genesis-biomed.com GENESIS Biomed - Corporate Presentation 15
01 Corporate Presentation of GENESIS Biomed A highly committed team Jordi Ortiz. MSc in Chemistry, Biochemistry field (Universitat de Barcelona) He completed his Master Thesis in Cation-induced aggregation and fusion of N-acyl-N-methylphosphatidyl- ethanolamine liposomes and continued his research by studying the lipid-protein interaction. In 1994, he joined the pharmaceutical industry and has occupied several positions, always in the R&D area (from Discovery to Clinical phases). He has worked in Sanofi, Ferrer and Spherium Biomed. In this last company he has hold the position of Senior Project Manager working in several projects from the discovery phase until the clinical research phase. He has an extended experience in several management positions in regulated analysis laboratories and as project manager with both large and small molecules. During the last years, he has been working in Autoinmune Diseases, Muscle recovery, ALS, Oncology Mucositis and Acute Kidney Injury. Jordi has also a deep expertise in European public fundraising and in Business Development activities, all of them related to the projects in which he has participated. Jordi Ortiz Senior Consutant He joins GENESIS Biomed in March 2019. He is a passionate of biomedical innovations of academic origin in order to jortiz@genesis-biomed.com accelerate their transition to the market. GENESIS Biomed - Corporate Presentation 16
01 Corporate Presentation of GENESIS Biomed A highly committed team Carles Taulé, BSc in Pharmacy (Universitat de Barcelona) and Master in Management of Biomedical Companies (CESIF). After several years as intern in Pharmacy Offices, in 2015 completes his Master Thesis in: “Role of Gram-positive vesicles in the acquired resistance mechanisms of staphylococcal biofilms” in Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg (Sweden). In 2017 he has been involved in several technology transfer projects at Fundació Bosch i Gimpera. Carles Taulé He joins GENESIS Biomed in September 2017. With a high entrepreneurial spirit, Carles is focused in the creation, Consultant valorization and fundraising of spin-off and start-up companies in the biomedical environment. ctaule@genesis-biomed.com BSc in Biotechnology (Universitat Autònoma de Barcelona, 2012), BSc in Biochemistry (Technische Universität Hamburg-Harburg, 2013) and Master in Pharmaceutical Industry and Biotechnology (Universitat Pompeu Fabra, 2015). Berta has worked for 2 years at the Tech Transfer Office of IDIBELL (Institut d'investigació Biomèdica de Bellvitge). Her fields of expertise are project management, fundraising and technology transfer. Previously, she worked as an intern at some R&D laboratories (Esteve, Charité, Humboldt University of Berlin and IMIM). Berta Borràs She joins GENESIS Biomed in May 2018. Science is her passion and she seeks to help entrepreneurs start their own Consultant business. bborras@genesis-biomed.com GENESIS Biomed - Corporate Presentation 17
01 Corporate Presentation of GENESIS Biomed A highly committed team BSc in Biology (Universitat de Barcelona, 2013) and Master in Genetics and Genomics (Universitat de Barcelona, 2014). In the lasts three years Mireia has worked as research assistant in various stem cell projects in the field of heart and and kidney differentiation in IBEC (Institut de Bioenginyeria de Catalunya). She joins GENESIS Biomed in June 2018. She loves science and looks forward to support the creation of new start- ups in the biomedical field. Mireia Samitier Consultant msamitier@genesis-biomed.com BSc in Biotechnology (Universitat de Vic, 2011) and Master in e-Health (Universitat Oberta de Catalunya, 2015). In the last two years Gisela has worked in the Tech Transfer and Innovation Office of Sant Pau Research Institute, with expertise in IP management and business development. She has three years of previous experience in e-Health Project Manager as well as QMS Responsible at an ICT SME for the health sector. She joins GENESIS Biomed in September 2018. Passionate about e-health and biotechnology, she seeks to help entrepreneurs to bring innovation to society. Gisela Gallego Consultant ggallego@genesis-biomed.com GENESIS Biomed - Corporate Presentation 18
01 Corporate Presentation of GENESIS Biomed A highly committed team BSc in Biomedical Sciences (Universitat de Lleida, 2018) and Master in Management of Biotech companies at CESIF. Anna has experience as a research assistant in some different areas (biophysics, neuroscience and pathological anatomy) in laboratories belonging to University of Pécs (Hungary), Universitat de Barcelona and HUAV Lleida. She developed her final dissertation in IDIBAPS (Barcelona) studying the role of nutrigenomics in the progression of type 2 diabetes. She has finished a Master in Management of Biotech companies (CESIF), acquiring all the necessary knowledge to develop her skills in the sector. Anna Miró Consultant Anna joins GENESIS Biomed in March 2019. She is willing to assist entrepreneurs in the establishment of their new amiro@genesis-biomed.com innovative companies. BSc in Biotechnology (Universitat de Barcelona, 2019) and MSc in Technology and Management of Biotech companies (CESIF, 2020). Alberto has experience as an undergraduate researcher in laboratories belonging to the University of Cologne (Germany). He developed his Bachelor´s Thesis in CECAD (Cologne) studying ubiquitin and its effect on cellular regulation and homeostasis under stress conditions, under the supervision of Dr. Mafalda Escobar-Henriques Dias. Eager to acquire and develop his career in Biotech based companies' management he is attending to a Master´s Degree in Technology and Management of such companies at CESIF. Alberto joins GENESIS Biomed in January 2020. Alberto Rodríguez With his scientific background he looks forward to help in the development of spin-off and start-up companies, Consultant trainee considering technology transfer as a tool of innovation. arodriguez@genesis-biomed.com GENESIS Biomed - Corporate Presentation 19
01 Corporate Presentation of GENESIS Biomed A highly committed team BSc in Biotechnology(Universitat de Barcelona, 2019) and Master in Management of Biotech companies at CESIF. Mariona studied Biotechnology and is currently attending a Master in Management of Biotech companies at CESIF in order to assist the establishment and growth of small biotechnological companies. She performed her final degree project in the Spin-off DBGen Ocular Genomics where she performed tasks related to the optimization of Inherited Retinal Disorders’ genetic diagnose. She joins GENESIS Biomed in January 2020. She is passionate of Life Sciences and looks forward to support spin-off Mariona Costa and start-up creation. Consultant trainee mcosta@genesis-biomed.com Degree in Journalism (Universitat Autònoma de Barcelona), postgraduate course in Medical Communications (Universitat Pompeu Fabra), Translation Studies at Universitat Autònoma and University of Glasgow and Digital Marketing in ESADE. Teresa has over 15 years experience as a reporter and communications specialist, mainly working for the healthcare sector, with a focus on digital health. In the last years she has worked for organizations such as Novartis, HIMSS Europe, Patient Power, UOC eHealth Center, UpToDate, Among Doctors, Mobile World Capital. Teresa’s areas of expertise include digital communications, social media, communications strategy, content production, digital marketing, media relations, PR, Patient Engagement. She has a large network of contacts in the health sector at a national and Teresa Bau international level. She is a member of the Catalan Association of Scientific Communication and the Journalists College. Communications Manager Teresa joins GENESIS Biomed in January 2020. tbau@genesis-biomed.com GENESIS Biomed - Corporate Presentation 20
01 Corporate Presentation of GENESIS Biomed Our Scientific Advisory Board Dr. Josep Tabernero Dr. Pere Ginés Chairman of the Board – Expert in Oncology Expert in Hepatology Chairman of Liver Unit, Hospital Clinic Barcelona; Full Professor Head of the Department of Medical Oncology in Vall d’Hebrón of Medicine, University of Barcelona; Director of Liver University Hospital; Director of the Vall d’Hebrón Research Transplantation; Head of Research Group, IDIBAPS and Institute in Oncology. CIBEReHD. Dr. Rafael Cantón Dr. José Luís Molinuevo Expert in Infectious Diseases Expert in Neurology Head of the Clinical Microbiology Department at the University Scientific director and Head of the Clinical, Biomarker and Risk Hospital Ramón y Cajal; associated Professor of Clinical Factors Research Group at the Barcelonabeta Research Centre Microbiology at Complutense University of Madrid. (BBRC); associate professor in University Pompeu Fabra. Dr. Francisco Fernández Avilés Dr. Rafael Simó Expert in Cardiology Expert in Endocrinology Full Professor of Cardiovascular Medicine at the Complutense Chair of the Division of Endocrinology and Nutrition at Vall University (UCM); Chairman of the Department of Cardiology in d’Hebron University Hospital; Director of Diabetes and the University Hospital Gregorio Marañón of Madrid; Scientific Metabolism Research Unit at Vall d’Hebron Research Institute Director of the Spanish Network Centre for Cardiovascular (VHIR); Professor of Medicine & Endocrinology at the Research (CIBERCV). Autonomous University of Barcelona. GENESIS Biomed - Corporate Presentation 21
01 Corporate Presentation of GENESIS Biomed The needs we understand for a fundraising process with a startup. Our Methodology For a fundraising process with a given startup, there are some important steps to accomplish prior starting the roadshow. For that purpose, an Interim CEO should lead the fundraising process, including: • Business plan preparation and cash need dimension • Fundraising strategy set up • Selection of the most suitable VCs for the fundraising, taking care of: • Lifecycle of the current funds • Lifecycle of the invested projects • Portfolio of invested projects • Preparation of the roadshow with investors • Starting of the fundraising process: • Non-confidential approaches and contacts • First TCs and meetings • Signature of NDA • Starting of building the syndicate up • Negotiation of the Term Sheet • Creation of a Data Room and coordination of the Due Diligence • Negotiation of the Investment and Shareholders Agreement • In the meanwhile, identification of the full-time CEO that will join the spin-off company GENESIS Biomed - Corporate Presentation 22
01 Corporate Presentation of GENESIS Biomed Our Methodology. Which are the 10 success factors to learn and implement? (1/5) 1. Market Analysis • Current unmet medical need • Epidemiology • Determination of market size • Description of market trends • Analysis of main players in the market (commercial products) • Description of the future competitors (development projects) 2. Competitive positioning • Analysis of main features of current and future competitors • Price analysis • Business model analysis • Market share analysis • Voice of Customer and Cost-effectiveness analysis • Competitors matrix GENESIS Biomed - Corporate Presentation 23
01 Corporate Presentation of GENESIS Biomed Our Methodology. Which are the 10 success factors to learn and implement? (2/5) 3. Proof of Concept results • Complete list and description of studies done till date • Main results obtained and conclusion analysis • Studies to be conducted in the future • Current agreement with the Main Institution • Outsourced studies and external collaborations • R+D Gantt chart 4. Intellectual Property • List of filed patents till date • Analysis of the current situation of each filed patent • List of potential future patents in the project • Freedom to operate analysis • License Agreement from the Institutions • IP strategy of the company GENESIS Biomed - Corporate Presentation 24
01 Corporate Presentation of GENESIS Biomed Our Methodology. Which are the 10 success factors to learn and implement? (3/5) 5. Regulatory Strategy • Regulatory framework for the current project • Analysis of the corresponding guidelines and directives • Current regulatory considerations • Future trends and regulatory changes • Regulatory strategy and validation • Regulatory roadmap 6. Development plan • List of all needed studies for the development of the product • Gantt chart for the whole development process • Identification of main milestones • Measurement of timelines • Identification of potential outsourced partners • Prediction of associated costs GENESIS Biomed - Corporate Presentation 25
01 Corporate Presentation of GENESIS Biomed Our Methodology. Which are the 10 success factors to learn and implement? (4/5) 7. Internal team of de company • Existing team and initial roles • Presence of a full-time CEO • Complete job description for all needed roles in the future • Organigram analysis and Headcount evolution in the company • Analysis of salaries and ESOP for internal staff • Partners Agreement, Governance and Reserved matters 8. External team • Profiles needed for the Scientific Advisory Board • Design of the Board of Directors • Identification of the Chairman • Identification of suitable outsourced roles and service providers • Analysis of costs and quotations • Design of ESOP for key external people GENESIS Biomed - Corporate Presentation 26
01 Corporate Presentation of GENESIS Biomed Our Methodology. Which are the 10 success factors to learn and implement? (5/5) 9. Financial Plan • Definition of the Business Model of the company • Quantification of the global cash need • General Risk Analysis and mitigation plan • Main financial milestones and Identification of Tranches • Fundraising strategy for Investors and Exit scenario analysis • Valuation of the company and Cap Table analysis • Preparation of the Financial Plan: CF, P&L and BS 10. Strategy and Fundraising negotiation • Selection of the most suitable investors • Preparation of the slide deck of the company • Roadshow and first meetings round • Building the syndicate up • Analysis and negotiation of the Term sheet • Preparation of Data room for Due diligence • Negotiation of the Investment Agreement and Partners Agreement • Closing of the Round GENESIS Biomed - Corporate Presentation 27
01 Corporate Presentation of GENESIS Biomed Last success cases in fundraising. Our Track record Signed deals Sector Round size Year Investors AptaTargets Pharma 4,5 M€ 2017 Caixa Capital Risc, Inveready Anaconda Biomed Medtech 15 M€ 2017 Ysios, Omega, Innogest, BSabadell Peptomyc Biotech 4,2 M€ 2017 ALTA Life Sciences, Healthequity GlyCardial Diagnostics IVD 3,1 M€ 2017 Caixa Capital Risc, Healthequity MJN Neuroserveis Medtech 750 k€ 2018 Ship2B and Family Offices Cornea Project IVD 300 k€ 2018 Industrial partner Corify Care Medtech 1 M€ 2019 Family Office and EU Funds Oxolife Pharma 300 k€ 2019 Family Office Cornea Project IVD 300 k€ 2019 Family Office LiverScreen Project Medtech 8,5 M€ 2019 EU Funds CreatSens IVD 750 k€ 2019 EU Funds ABLE Human Motion Medtech 2,5 M€ 2019 EU Funds GENESIS Biomed - Corporate Presentation 28
01 Corporate Presentation of GENESIS Biomed Our success stories in fundraising • Medtech project: stratification of patients suffering from atrial fibrillation • 1 M€ raised in January 2019 • Investors: Family offices and EU funds • Pharma project: new aptamer for ischemic stroke • 2,7 M€ raised in May 2017 • Investors: Caixa Capital Risc and Inveready • Medtech project: new catheter for thrombectomy • 15 M€ raised in May 2017 • Investors: Ysios, Omega, Innogest, Banc Sabadell • Biotech project: recombinant protein for NSCLC and TNBC • 4,2 M€ raised in July 2017 • Investors: ALTA Life Sciences and Healthequity • IVD project: new biomarker for cardiovascular ischemia • 2,4 M€ raised in October 2017 • Investors: Caixa Capital Risc and Healthequity GENESIS Biomed - Corporate Presentation 29
01 Corporate Presentation of GENESIS Biomed Current projects in fundraising process Company sector Product Indication Round size Ophtalmology IVD Cornea disorders 3,6 M€ Cardiovascular Medtech Atrial fibrillation 15 M€ Nephrology IVD Renal failure 300 k€ Women’s health Pharma Fertility 8,1 M€ Gastrointestinal Medtech Chronic Constipation 5 M€ Ophtalmology Pharma Retinitis pigmentosa 500 k€ GENESIS Biomed - Corporate Presentation 30
02 Presentation of our new fund GENESIS Ventures GENESIS Biomed - Corporate Presentation 31
02 Presentation of GENESIS Ventures Context and need for a New Fund in Tech Transfer (1/2) Activities for GENESIS Biomed during this year GAP Business plan Fundraising General Interim CEO Projects need to be valorised preparation support support… Month -12… Month -6 Month 0 Month 6 Month 12 GENESIS Biomed starts After the work done by The startup is founded working with a client GENESIS, the project is and the financial round coming from hospital, ready to start roadshow is closed. The project university or research with VC investors development starts… center GENESIS Biomed - Corporate Presentation 32
02 Presentation of GENESIS Ventures Context and need for a New Fund in Tech Transfer (2/2) Questions related to this GAP: 1. All researchers lack of funds for the valorisation of their projects 2. Usually the researchers are not business oriented when deciding which studies to perform 3. With funds & advise, the GAP can be shortened and the project can be ready to start the fundraising process in advance GENESIS Biomed - Corporate Presentation 33
02 Presentation of GENESIS Ventures Lifecycle and portfolio management for GENESIS Ventures GENESIS Ventures The spin-off is The series A is closed with invests in the founded and GV VC investors. GV remains as research project becomes shareholder shareholder until the exit Period of time in which the ticket will be devoted to the valorisation of the Period of time in which GENESIS Biomed will support the spinoff (potential GENESIS’ client) research project (new experiments to generate new results to increase the project value) in the fundraising process to finally close a series A with Venture Capital GENESIS Biomed - Corporate Presentation 34
02 Presentation of GENESIS Ventures Investment policy with a given identified project that will become spin-off in 1 year Phase 1: Pre-foundation of the spin-off Phase 2: Foundation of the spin-off Our Total Fund: 2,0 M€ After the investment period, the spinoff company should be founded. If the spinoff is not founded and the project is licensed to a third party, the Investment Agreement regulates the return to GENESIS Ventures (via upfront and/or royalties). Tickets*: 25.000 – 100.000 € In the foundation, GENESIS Ventures acquires the corresponding shares committed Investment Agreement is signed in the Investment Agreement. Our policy is not to become a major shareholder. with Research Center and Research Group After the foundation, GENESIS Biomed will help the new spinoff (becoming potential GENESIS’ client) in the fundraising process in order to close a series A with Venture Max. time to found NewCo*: 1 year Capital investors. GENESIS Biomed will manage the projects and will inform the Exit scenario: the standard exit scenario for Venture Capital once the Company is Investments Committee acquired or the project is out-licensed to a third party. * Orientative figures. These will be fixed in a case-by-case basis GENESIS Biomed - Corporate Presentation 35
02 Presentation of GENESIS Ventures Our invested projects till date ELEM ADmit Tx Aptamer Quality MOWOOT NeuroHeal Pharma Spinoff UAB Spinoff BSC-UPC Spinoff IDIBELL project Start-up Spinoff IRYCIS Medtech Developing a new Developing a new Spinoff Karolinska Developing a new Developing a new software for IVD for early Developing a new solution for SCI therapy for virtualization of detection of aptamer for Breast Developing a new and chronic neuroregeneration human organs Alzheimer Disease Cancer CDSS constipation Ticket: 150.000€ Ticket: 75.000€ Ticket: 100.000€ Ticket: 50.000€ Ticket: 100.000€ Ticket: 100.000€ LIMNO Aortyx Spinoff CSIC Spinoff IQS SHBG ABLE CreatSens DropLite Spinoff VHIR Spinoff UPC Spinoff URV Spinoff ICFO Developing a new Developing a new therapy for Developing a new Developing a new Developing a new Developing a new device for aortic retinitis therapy for obesity exoskeleton for SCI IVD for CKD IVD for AH aneurism pigmentosa Ticket: 50.000€ Ticket: 50.000€ Ticket: 50.000€ Ticket: 50.000€ Ticket: 100.000€ Ticket: 125.000€ GENESIS Biomed - Corporate Presentation 36
©GENESIS Biomed Barcelona Office: Barcelona Science Park Tower I, offices 3B01-03-05-06 GENESIS Biomed is member of: Baldiri Reixac 4-8 08028 Barcelona +34 93 403 58 53 Madrid Office: Velázquez 25, 2º A 28001 Madrid contact@genesis-biomed.com GENESIS Biomed - Corporate Presentation 37
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