DRAFT HUMAN HEALTH, LIFE SUPPORT AND HABITATION SYSTEMS - NOVEMBER 2010 - NASA

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DRAFT HUMAN HEALTH, LIFE SUPPORT AND HABITATION SYSTEMS - NOVEMBER 2010 - NASA
National Aeronautics and Space Administration

        DRAFT Human Health, Life Support and
        Habitation Systems
        Technology Area 06

        Kathryn Hurlbert, Chair
        Bob Bagdigian
        Carol Carroll
        Antony Jeevarajan
        Mark Kliss
        Bhim Singh

      November • 2010
                                            DRAFT
DRAFT HUMAN HEALTH, LIFE SUPPORT AND HABITATION SYSTEMS - NOVEMBER 2010 - NASA
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              DRAFT
DRAFT HUMAN HEALTH, LIFE SUPPORT AND HABITATION SYSTEMS - NOVEMBER 2010 - NASA
Table of Contents
Foreword
Executive Summary                                                                   TA06-1
1. General Overview                                                                 TA06-2
 1.1. Technical Approach                                                            TA06-2
 1.2. Benefits                                                                      TA06-2
 1.3. Applicability/Traceability to NASA Strategic Goals, AMPM, DRMs, DRAs          TA06-2
 1.4. Top Technical Challenges                                                      TA06-5
2. Detailed Portfolio Discussion                                                    TA06-6
 2.1. Environmental Control and Life Support Systems (ECLSS) and Habitation Systems TA06-7
   2.1.1. Approach and Major Challenges                                             TA06-7
 2.2. Extra-Vehicular Activity (EVA) Systems                                       TA06-10
   2.2.1. Approach and Major Challenges                                            TA06-11
 2.3. Human Health and Performance (HHP)                                           TA06-12
   2.3.1. Approach and Major Challenges                                            TA06-14
 2.4. Environmental Monitoring, Safety, and Emergency Response (EMSER)             TA06-16
   2.4.1. Approach and Major Challenges                                            TA06-17
 2.5. Radiation                                                                    TA06-17
   2.5.1. Major Approach and Challenges                                            TA06-19
3. Interdependency with Other Technology Areas                                     TA06-21
4. Possible Benefits to Other National Needs                                       TA06-21
Acronyms                                                                           TA06-24
Acknowledgements                                                                   TA06-24

                                         DRAFT
DRAFT HUMAN HEALTH, LIFE SUPPORT AND HABITATION SYSTEMS - NOVEMBER 2010 - NASA
Foreword
NASA’s integrated technology roadmap, including both technology pull and technology push strategies,
considers a wide range of pathways to advance the nation’s current capabilities. The present state of this effort
is documented in NASA’s DRAFT Space Technology Roadmap, an integrated set of fourteen technology
area roadmaps, recommending the overall technology investment strategy and prioritization of NASA’s
space technology activities. This document presents the DRAFT Technology Area 06 input: Human Health,
Life Support and Habitation Systems. NASA developed this DRAFT Space Technology Roadmap for use by
the National Research Council (NRC) as an initial point of departure. Through an open process of community
engagement, the NRC will gather input, integrate it within the Space Technology Roadmap and provide NASA
with recommendations on potential future technology investments. Because it is difficult to predict the wide
range of future advances possible in these areas, NASA plans updates to its integrated technology roadmap on
a regular basis.

                                                   DRAFT
Executive Summary                                       lieve that each activity or milestone represented in
  This roadmap provides a summary of key capa-          the TASR does indeed have a technology solution
bilities in the domain of TA06, Human Health,           to pursue at the present time, or will have within
Life Support and Habitation Systems (HLHS),             the timeframe shown. Each sub-TA portion of the
necessary to achieve national and agency goals in       roadmap is detailed in Section 2, providing fur-
human space exploration over the next few de-           ther explanation of the sub-TA as well as a sum-
cades. As an example, crewed missions venturing         mary table of the priority technologies and/or sys-
beyond Low-Earth Orbit (LEO) will require tech-         tem functional areas of interest, the current SOA,
nologies with improved reliability, reduced mass,       the major challenges for advancement, and the
self-sufficiency, and minimal logistical needs as an    recommended milestones/activities to advance to
emergency or quick-return option will not be fea-       a TRL-6 or beyond (i.e., demonstration in a rele-
sible. The sub-technology areas (sub-TAs) includ-       vant mission environment or simulation thereof ),
ed in the roadmap are Environmental Control             which correlates with the TASR content. Section
and Life Support Systems (ECLSS) and Habita-            2 also provides some example technological solu-
tion Systems; Extra-Vehicular Activity (EVA) Sys-       tions, but these should not be considered all-in-
tems; Human Health and Performance (HHP);               clusive or decisive without rigorous survey of SOA
Environmental Monitoring, Safety, and Emergen-          and proposed technologies and further review/
cy Response (EMSER); and Radiation.                     study. Some major technical challenges identified
  Shown on the next page is an overview road-           for each sub-TA are presented in Section 1.4, for
map (called the Technology Area Strategic Road-         periods spanning the next two decades.
map (TASR)), which includes planned, predict-              As can be seen in the TASR, milestones are
ed, and new proposed missions and milestones            aligned to minimize the number of necessary
at the top. Examples of the planned and predict-        flights to progress the technologies and maximize
ed missions are human missions to LEO (e.g., In-        the use of integrated ground tests/demonstrations
ternational Space Station (ISS)) and Near-Earth         of new technologies for reduced risk. The ‘flight
Objects (NEOs). More detail on these “pull” mis-        campaigns’ serve as validation beacons to project
sions and milestones is given in Section 1.3. In        managers of future missions. It is recognized that
addition, new “push” missions and milestones are        validation to TRL-6 should occur by the Prelim-
proposed, and represent key events that would ad-       inary Design Reviews (PDRs) of these missions;
vance or validate technologies to a point where         PDR is targeted for no later than three years be-
they would be available to implement into future        fore launch readiness, and more often desired five
missions at low risk. An example “push” mission is      to six years before human missions.
the extension of ISS operations beyond 2020, to            The primary benefit of investment in technolo-
allow for continued and sustained testing and ad-       gy development for the HLHS domain is the abil-
vancements related to space-environment effects         ity to successfully achieve human space missions
on humans.                                              to LEO and well beyond, as described in Section
  The lower portion of the TASR is populated            1.2. At the same time, significant potential exists
with technology milestones and activities for each      for improvements in the quality of life here on
of the sub-TAs, as recommended to allow signif-         Earth and for benefits of national and global inter-
icant advancements to support the missions and          est. Section 4 provides an extensive description of
milestones identified. The icons are designated         how investment in HLHS can provide technolo-
in the legend at the bottom, and distinguish be-        gies for climate change mitigation, emergency re-
tween “pull” that directly tie to a mission, activity   sponse, defense operations, human health, biolog-
or milestone, versus “push” where there is no di-       ical breakthroughs, and more.
rect link but a recommendation/path to support             The OCT Roadmapping activity is intended to
future needs. Also, distinction is made for ground      identify overlaps across TAs, and for the topical
versus flight activities, and cross-cutting technol-    areas of TA06, HLHS, many such overlaps exist.
ogies are identified. Notably, some technologies        Notably, the greatest overlap occurs with TA07,
in the roadmap are currently at a low Technology        Human Exploration and Development of Space
Readiness Level (TRL), but could provide signifi-       (HEDS). Delineation exists in that the focus of
cant advancement in the current State-of-the-Art        HLHS is specific to the human element, includ-
(SOA) and/or drive new approaches or techniques         ing technologies that directly affect crew needs for
in accomplishing mission implementation. The            survival, human consumption, crew health and
subject matter experts authoring this roadmap be-       well-being, and the environment and/or interfaces

                                                 DRAFT                                               TA06-1
to which the crew is exposed. Alternately, HEDS        proposed technologies as well as associated mile-
focuses on the global architecture and overall in-     stones and missions correlating to the TASR.
frastructure capabilities to enable a sustained hu-    Also, the TASR milestones are aligned to mini-
man presence for exploration destinations. More        mize the number of necessary flights to progress
detail on HLHS relationships to the other TAs is       the technologies and maximize the use of integrat-
included in Sections 2.0 and 3.0.                      ed ground tests/demonstrations for reduced risk.
                                                       The ‘flight campaigns’ serve as validation beacons
1. General Overview                                    to project managers of future missions. It is rec-
                                                       ognized that validation to TRL-6 should occur by
1.1. Technical Approach                                the Preliminary Design Reviews of these missions;
   This roadmap provides a summary of key ca-          PDR is targeted for no later than three years be-
pabilities, including game-changing or break-          fore launch readiness, and more often desired five
through items, within the domain of TA06,              to six years before human missions.
HLHS, necessary to achieve predicted national
and agency goals in space over the next few de-        1.2. Benefits
cades. As an example, crewed missions venturing          The primary benefit of significant technology
beyond LEO will require technologies for high re-      development for the HLHS domain is the abili-
liability, reduced mass, self-sufficiency, and min-    ty to successfully achieve affordable human space
imal logistical needs, as an emergency or quick-       missions to LEO and well beyond. Continued ISS
return option will not be feasible. Human space        operation and missions will directly contribute to
missions include other critical elements such as       the knowledge base and advancements in HLHS
1) EVA systems to provide crew members protec-         in the coming decade, as a unique human-tended
tion from exposure to the space environment dur-       test platform within the space environment. Ei-
ing planned and contingency/emergency opera-           ther extension of ISS operations, or using an al-
tions; 2) crew health care to address physiological,   ternative permanent or semi-permanent in-space
psychological, performance and other needs in-si-      facility would facilitate sustained research/testing
tu; 3) monitoring, safety, and emergency response      and associated advancements into the following
systems such as fire protection and recovery, envi-    decade as well, in preparation for missions beyond
ronmental monitoring sensors, and environmen-          LEO. In-space test beds will be crucial to the de-
tal remediation technologies; and 4) systems to        velopment and validation of technologies needed
address radiation health and performance risks,        for those bold space missions, such as a NEO, cur-
and shielding and other mitigations.                   rently under consideration.
   The TASR provides a top-level overview of the         The proposed roadmap includes many suggest-
roadmap content herein. The missions shown in-         ed in-flight and ground test activities for pre-flight
clude those to LEO (e.g., ISS) and other poten-        evaluation and augmented research/testing of rec-
tial destinations beyond (e.g., NEO). In addition,     ommended technologies, which will regularly and
“push” missions and milestones are recommended         efficiently provide advancements during the de-
for consideration, which represent key events for      velopment phases. More details on the benefits
advancement or validation of technologies and/         for each entry are defined in subsequent sub-TA
or a point where the technologies could be avail-      sections. Additionally, Section 4 provides an ex-
able to implement for future missions. An exam-        tensive description of how investment in HLHS
ple “push” mission is the extension of ISS oper-       technologies can lead to improvements in the
ations beyond 2020 to allow for continued and          quality of life here on Earth and create benefits
sustained testing and advancements related to          of national and global interest. Examples include,
space-environment effects on humans. Notably,          but are not limited to, technologies related to cli-
some technologies in the roadmap are currently at      mate change mitigation, emergency response, mil-
a low TRL, but could provide significant advance-      itary operations, human health, and biological sci-
ment in the SOA and/or drive new approaches or         ence breakthroughs.
techniques in accomplishing mission implemen-          1.3. Applicability/Traceability to NASA
tation.                                                       Strategic Goals, AMPM, DRMs, DRAs
   The HLHS sub-TAs detailed in the roadmap              The process to develop the TASR included 1)
content herein are ECLSS and Habitation Sys-           initial consideration of the overall agency goals,
tems; EVA Systems; HHP; EMSER; and Radi-               outcomes, and objectives as “pull” missions for the
ation. Section 2 details each sub-TA, including        technology content and milestones; and 2) incor-

TA06-2                                          DRAFT
Figure 1: Human Health, Life Support and Habitation Systems Roadmap

                                                                      DRAFT   TA06–3/4
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poration of the NASA Mission Directorate and                                      this technology area (TA) exists; however, the dis-
NASA Centers needs and focus within the sub-                                      tinction is that TA06, HLHS, is specific to the
TAs. While the strategic plan for the agency, and                                 human element, including technologies that di-
therefore its strategic goals, specific missions, etc.,                           rectly affect crew needs for survival, human con-
is currently being finalized, the top portion of the                              sumption, crew health and well-being, and the en-
roadmap does include the proposed agency-level                                    vironment and/or interfaces to which the crew is
major missions and milestones derived from the                                    exposed. For the TA06, HLHS, drafted roadmap
drafted FY11 Agency Mission Planning Manifest                                     herein, some “push” missions and milestones are
(AMPM) ; an example is the planned ISS opera-
              1
                                                                                  also recommended for consideration, like extend-
tions through 2020. In addition, some content re-                                 ed operation of the ISS. It should be noted that
lated to Design Reference Missions (DRMs) were                                    alternative platforms might serve this purpose as
based on Design Reference Architectures (DRAs)                                    well, such as commercial or joint space stations/
evaluated as a part of the Human Exploration                                      vehicles, if available and appropriate for the pro-
Framework Team (HEFT) activity ; an exam-               2
                                                                                  posed technologies.
ple is the assumed human missions beyond LEO,                                       The proposed roadmap provides time phasing
such as the mission to a NEO/Near-Earth Aster-                                    that would allow infusion of technologies or ca-
oid (NEA), within the 2025 timeframe. An at-                                      pabilities to support planned, predicted, and new
tempt was also made to consider the relevant mis-                                 proposed agency missions and/or milestones.
sions and milestones included on TA07, Human                                      Once the agency direction and authorization for
Exploration and Development of Space (HEDS),                                      FY11 and beyond is finalized, the roadmap should
Roadmap, as considerable potential overlap with                                   be re-evaluated.
1         Agency Mission Planning Manifest. Draft internal NASA                   1.4. Top Technical Challenges
document. 2011.
2         Human Exploration Framework Team (HEFT) DRM Re-
                                                                                    The table below summarizes some major techni-
view - Phase 1 Closeout, September 2, 2010.                                       cal challenges that will be faced in the continua-
Table 1. Major Technical Challenges
                                                                        Present – 2016
 Integrate fundamental research results on radiation environment biological effects, and including other effects from space exposure, into damage/risk
 model(s) and consolidate and interpret databases of major signaling pathways causative of cancer from space exposure and other damage
 Stabilize liquid and solid wastes to recover water and to control pathogens, biological growth and gas/odor production
 Achieve high reliability and reduce dependence on expendables over existing SOA systems that recover O2 from CO2 and H2O from humidity condensate
 and urine
 Develop advanced screening technologies, to detect and/or predict subclinical malignancies, subclinical cataracts, individual susceptibility levels to space
 exposure (e.g., radiation) and carbon dioxide exposures, osteoporosis, oxidative stress, renal stone formation, anxiety, and depression
 Demonstrate EVA technologies that could be used to extend EVA capability on ISS beyond 2020. These technologies include advances for on-back regener-
 able CO2 and humidity control, advanced suit materials, and more capable avionics
 Demonstrate real time airborne particle monitoring on the ISS
                                                                         2017 – 2022
 Develop radiation risk model(s) as a predictive systems biology model approach for space radiation, including development of experimental methods/
 techniques and models to verify integrated risk and understand synergistic effects of other spaceflight stressors (microgravity, reduced immune system
 response, etc.) combined with radiation
 Validate physiological and psychological countermeasures for long-duration missions, which can include any combination of exercise, non-exercise (e.g.,
 pharmacological) and/or advanced techniques (e.g., Virtual Reality technologies such as a “Holodeck”, artificial gravity)
 Close high-reliability ECLSS more fully, with >95% O2 and H2O recovery from an integrated mission perspective
 Implement bulk food processing in-flight and augmentation of food supply with plants
 Advanced EVA technologies to enable missions to NEOs, which includes suits that incorporate advanced materials and component demonstrations of life
 support technologies that reduce consumables
 Complete development of a distributed hybrid fire-detection system for space missions
                                                                         2023 – 2028
 Demonstrate hybrid physical/chemical and biological ECLSS with >95% recovery of O2 and H2O with bulk food production
 Develop and validate a non-ionizing, full body, dynamic, 3-D imaging with in-situ diagnosis and treatment capabilities (e.g., renal stone ablation)
 Validate real-time monitoring and forecasting space weather model(s), to include prediction of onset and evolution of Solar Particle Events (SPEs) as well as
 all clear periods
 Flight demonstration of an advanced EVA system, including suits that utilize multifunctional materials, a portable life-support system (PLSS) with no con-
 sumables, on-suit power generation, and avionics that enable the crew to operate autonomously
 Complete integrated system testing of portable, non-solvent-based microbial remediation on ISS

                                                                         DRAFT                                                                         TA06-5
tion and progression of human spaceflight, espe-       2. Detailed Portfolio
cially for crewed missions beyond LEO. The listing        Discussion
was determined by reviewing the recommended              This document provides a summary of key ca-
content for each sub-TA for the time period spec-      pabilities in the TA06, HLHS, domain, recom-
ified, and selecting one or two technologies and/      mended to achieve predicted national and agen-
or priority system functions within that domain        cy goals in space over the next few decades. The
for a balanced representation of HLHS. The table       sub-TAs, illustrated in Figure 2, are described in
specifies technologies that are a low TRL and re-      more detail in subsequent sections. Notably, for
quire extended development time to be ready for        TA06, HLHS, the greatest TA interdependen-
future missions, those that may significantly im-      cy is with TA07, HEDS. Substantial delineation
pact mission implementation (e.g., high reliabil-      between the two TA scopes does exist. HLHS
ity, reduced logistics, decreased mass, high effi-     concentrates specifically on the human element,
ciency power systems, etc.), and/or those that are     whereas HEDS focuses on the global architecture
critical to human safety and well-being. An exam-      and overall infrastructure capabilities to enable a
ple is that top priorities for ECLSS include matur-    sustained human presence for exploration desti-
ing technologies for high reliability and reduced      nations. The HLHS domain includes technol-
logistics, as supported by the recent HEFT activ-      ogies that directly affect crew needs for survival,
ity . The recommended activities and milestones
    3
                                                       human consumption, crew health and well-being,
related to the challenges listed below, and those in   and the environment and/or interfaces to which
the Section 2 tables for each sub-TA, are direct-      the crew is exposed. An example is water technol-
ly correlated to the TASR content. The TASR also       ogies, which are needed for direct human water
shows when the milestones and activities related       intake, but also for hygiene and humidity control.
to the challenges are intended to be met.              This is distinguished from HEDS, for which the
                                                       water focus is on extraction from in-situ materials
3        Ibid.                                         for use in vehicle systems, or optimal placement
                                                       of storage tanks to maximize radiation shielding

Figure 2. Technology Area Breakdown Structure (TABS)
TA06-6                                          DRAFT
without affecting the functional architecture. An-      venting or de-orbiting in spent resupply vehicles.
other example is that for HLHS, the EVA systems         Longer-duration missions demand that reusable
are those that directly interface to the human and      water be recovered from wastewater in order to
provide the life support, such as the suit itself and   reduce or eliminate the need for Earth-based re-
the support systems. Conversely, in HEDS, for           supply. Short- and long-duration missions typical-
the EVA systems include the mobility technolo-          ly also require some degree of wastewater stabili-
gies needed to interface to the vehicles/systems at     zation to protect equipment and facilitate potable
the exploration site(s) and to the components, in       water disinfection for storage.
order to conduct human mission operations; ex-             Waste Management – The objective of this el-
amples include a suitport and/or suitlocks, rovers,     ement is to safeguard crew health, increase safety
tools and translation aids. Another area of poten-      and performance, recover resources, and protect
tial overlap for both TAs is food preparation and       planetary surfaces, all while decreasing mission
production, but this too has been resolved: for         costs. Key technology gaps to be addressed for
HLHS, food is a critical consumable for humans          future missions include waste/trash volume re-
and provides a future interface to the life support     duction and stabilization, water recovery from
system for carbon dioxide scrubbing. For HEDS,          wastes, and ultimately a high-percentage recovery
the primary concentration is on production and          of H2O, O2, N2, CO2, and minerals. Additional
preservation of food for in-transit space and desti-    technology gaps include waste collection, disposal
nations, to minimize human-specific logistics and,      and containment technologies, and source odor/
therefore, support self-sufficiency for remote mis-     contaminant control.
sions beyond LEO. Overlaps with other TAs are              Habitation – This area focuses on habitation
described briefly in Section 3.                         functions that closely interface with life support
2.1. Environmental Control and Life                     systems, including food preparation and produc-
       Support Systems (ECLSS) and                      tion, hygiene, metabolic waste collection, cloth-
       Habitation Systems                               ing/laundry, and the conversion of logistics trash
  The main objective of spacecraft life support and     to resources. Other habitation functions such as
habitation systems is to maintain an environment        deployable crew volumes, habitation analogs,
suitable for sustaining human life throughout the       lighting, housekeeping tools, and noise mitigation
duration of a mission. The ECLSS and Habitation         are addressed in TA07, HEDS.
System includes four functions, each of which is        2.1.1. Approach and Major Challenges
described below.                                           The basic human metabolic spacecraft require-
  Air Revitalization – The overarching function         ments of oxygen, water, and food have been well
of this element is to maintain a safe and habitable     characterized, and these requirements have largely
atmosphere within a spacecraft, surface vehicle,        been met for short-duration missions (from Proj-
or habitat. This is achieved through the remov-         ect Mercury to the Space Shuttle) with open-loop
al of carbon dioxide, trace volatile organic com-       life support systems using expendables.
pounds, and particulates that are released into the        For the ISS, continual operational costs of a
atmosphere from crew member and vehicle sourc-          conventional open-loop system are prohibitive.
es. Oxygen and nitrogen are added to the atmo-          Accordingly, the ISS life support systems process
sphere in controlled manners to maintain cabin          condensate and urine into potable water. An up-
pressures and composition, and to make-up for           coming technology demonstration will also enable
metabolic consumption and loss. Ventilation mix-        recovery of half of the oxygen available in carbon
es atmospheric constituents and transports sensi-       dioxide. This approach is a significant advance
ble and latent heat loads to rejection devices. In      over previous systems, but many of the technical
long-duration missions, oxygen and carbon can be        solutions to human life support for the ISS de-
recovered from carbon dioxide and recycled to re-       pend upon reliable system operation and timely
duce mission life-cycle costs and upmass.               logistical support from Earth.
  Water Recovery and Management – This ele-                As NASA looks toward human missions be-
ment provides a safe and reliable supply of pota-       yond LEO, two key distinctions exist from all
ble water to meet crew consumption and opera-           crewed space missions to date: 1) human beings
tional needs. Short-duration missions often can be      will spend significantly longer periods of time far-
executed by using launched water supplies com-          ther from reliable logistics depots, and 2) an emer-
bined with disposing wastewater via overboard           gency quick-return option will not be feasible.

                                                 DRAFT                                               TA06-7
Accordingly, to sustain life on long-duration mis-      pabilities with the optimal combination of mass,
sions beyond LEO, high reliability will become an       size, reliability, logistics, and loop closure charac-
increasingly dominant design driver. Therefore,         teristics that will best support the given mission
the ECLSS and Habitation Systems technical area         scenario.
must develop and mature technologies that em-             In maturing these technologies, life support and
phasize 1) high-reliability processes and integrated    habitation systems for missions beyond LEO will
systems that employ autonomous monitoring and           need to address both the technological shortcom-
control systems and that are easily maintained by       ings and the functional integration inefficiencies
the crew; 2) increased self-sufficiency, enabled by     of existing systems. Further reduction of life-cy-
highly reliable means of recovering life-supporting     cle costs and closure of life support systems is par-
commodities such as oxygen, water, and food; and        amount, including focus on the key challenges
3) minimized logistics supply to diminish overall       summarized in Table 2.
mass of spares, maintenance equipment, clothing,          Air revitalization is typically achieved by the
food containers, and other items requiring stow-        combined operation of many individual equip-
age mass and volume.                                    ment items, each optimized to perform one or two
  Reliability, logistics, and loop closure all con-     functions . Utilization of multifunctional materi-
                                                                     4

tribute to overall mission life-cycle costs. As ca-     als and processes can reduce system size and oper-
pabilities to recover and produce life support con-     ational complexity, regardless of mission duration.
sumables (O2, H2O, food) are added to a launch          Such multifunctional systems must be developed
vehicle, initial mass may be increased for addition-    to avoid burdensome maintenance or repair. Al-
al system hardware, spare parts, and expendable         though air revitalization life-cycle costs for long-
supplies. Depending on the mission duration and         duration missions are dominated by the degree
operations concept, these initial penalties need to     of oxygen recovery, system reliability and utiliza-
be justified by the resultant long-term consum-         tion of expendables also contribute substantially
ables savings. Architectural trades uncover which       to mission economics and probability of success.
combinations of capabilities yield the lowest life-     Reliability drivers include dynamic electrome-
cycle cost for a given mission duration and con-        chanical devices (valves and valve position indi-
cept. A representative break-even comparison of         cators, compressors, etc.) as well as components
this type is shown in Figure 3. The goal of life sup-   often considered “static” due to material attrition
port and habitation architecture is to select the ca-   and loss of critical properties over time (sorbents,
                                                        heat exchanger coatings, membranes, etc.). Oper-
                                                        ating equipment and airflows produce substantial
                                                        acoustic emissions that dominate the cabin envi-
                                                        ronment and require system size increases to ac-
                                                        commodate marginally-effective acoustic treat-
                                                        ments. Overboard venting of process gases as well
                                                        as residual atmosphere constituents during airlock
                                                        operations may require substantially greater con-
                                                        trols on planetary surfaces than has been histori-
                                                        cally required in LEO in order to meet planetary
                                                        protection requirements. Mission concepts that
                                                        require the recharge of oxygen accumulators drive
                                                        the need to reliably generate or compress gaseous
                                                        oxygen to high pressures or liquefy it to achieve
                                                        high storage densities.
                                                          Similar to air revitalization, life-cycle costs for
                                                        water recovery and management are dominated
                                                        by the degree of water recovery, system reliabili-
                                                        ty, and utilization of expendables. As in air revi-
                                                        talization, reliability drivers include both dynamic
Figure 3. Representative Comparison of Life-Cycle       4          Perry, J., Bagdigian, R., and Carrasquillo, R., 2010, “Trade
   Mass Predictions, Candidate ECLSS Architec-          Spaces in Crewed Spacecraft Atmosphere Revitalization System Devel-
                                                        opment.” Paper presented at 40th International Conference on Environ-
   tural Approaches                                     mental Systems, Barcelona, Spain, July 11-15.

TA06-8                                           DRAFT
Table 2. ECLS and Habitation Technical Area Details
Function             Current SOA/Practice                               Major Challenge(s)                                   Milestones/Activities to Ad-
                                                                                                                             vance to TRL-6 or beyond
Air Revitalization   CO2 removal via expendable lithium hydroxide       Attain high reliability                              2011-14: 75% O2 recovery
                     and regenerable molecular sieves [TRL-9] and
                     amines [TRL-6]                                     Reduce utilization of expendables                    2011-14: Variable cabin pressure
                                                                                                                             control
                     O2 supply via compressed gas delivery, scav-       Reduce power and equipment mass and
                     enging of cryogenic fuel cell reactant boil-off,   volume                                               2015-19: 100% O2 recovery
                     consumption of expendable perchlorate
                     candles, and water electrolysis                    Increase recovery of O2 from CO2                     2020-24: O2 recovery augmented
                                                                                                                             by crop systems and life-support-
                     50% O2 recovery from CO2 [Sabatier TRL-7]          Reduce acoustic emissions                            ing materials

                     Trace contaminant removal via catalytic oxida-     Control environmental mass exchanges to              2025-29: O2 recovery principally
                     tion and expendable sorbents                       ensure planetary protection                          provided by crop systems and life
                                                                                                                             supporting materials
                     Particulate filtration                             System impacts of cabin atmospheres with
                                                                        reduced total pressures and elevated oxygen
                     Ducted fans                                        concentrations

                     Air/liquid heat exchangers (condensing, non-       Develop and validate complex models and
                     condensing)                                        simulations (e.g., Computational Fluid Dynam-
                                                                        ics (CFD), human metabolic models, chemical
                                                                        and microbial processes)
Water Recovery       H2O recovery from humidity condensate and          Attain high reliability                              2011-14: 40-55% H2O recovery
and Manage-          urine only (representing only 15-20% of the                                                             (condensate, urine, hygiene)
ment                 anticipated wastewater load for exploration        Reduce utilization of expendables
                     missions)                                                                                               2015-19: 98% H2O recovery (con-
                                                                        Reduce power and equipment mass and                  densate, urine, hygiene, laundry,
                                                                        volume                                               waste)

                                                                        Reduce acoustic emissions                            2020-24: 98% H2O recovery
                                                                                                                             augmented by biological systems
                                                                        Recover water from additional sources, includ-       (condensate, urine, hygiene,
                                                                        ing hygiene and laundry                              laundry, waste, In-Situ Resource
                                                                                                                             Utilization (ISRU)-derived)
                                                                        Increase overall water recovery percentage
                                                                                                                             2025-29: 98% H2O recovery
                                                                        Stabilize wastewater from multiple sources in        principally provided by biological
                                                                        manners that are compatible with processing          systems
                                                                        systems

                                                                        Disinfect and maintain microbial control of po-
                                                                        table water by means that protect crew health
                                                                        and provide reliable monitoring
Waste Manage-        Single-use supplies and return of all wastes to    Attain high reliability                              2011-14: Waste stabilization and
ment                 Earth for disposal                                                                                      volume reduction
                                                                        Reduce utilization of expendables
                                                                                                                             2015-19: H2O recovery from
                                                                        Reduce power and equipment mass and                  wastes
                                                                        volume
                                                                                                                             2020-24: Waste mineralization
                                                                        Stabilize wastes to control pathogens, biologi-
                                                                        cal growth, and gas/odor production                  2025-29: >95% waste resource
                                                                                                                             recovery
                                                                        Resource Recovery – recover H2O and other re-
                                                                        sources (O2, CO2, N2, minerals, clothing radiation
                                                                        shielding, and fuel)
                                                                        Planetary Protection compatibility
Habitation           Limited clothing reuse prior to disposal (0.38     Odor/microbial control for multiple uses – limit-    2011-14: Long-wear clothing; 50%
                     kg/crew-day) – no in-flight laundry capability     ing impact on wastewater processor                   less food packaging
                     All ISS food requires ground resupply – zero-g
                     plant growth demonstrated                          Simplified bulk food preparation and continu-        2015-19: Reusable clothing; fresh
                                                                        ous low-energy and low-volume food produc-           food augmentation
                                                                        tion
                                                                                                                             2020-24: Bulk food processing
                                                                        Laundry systems
                                                                                                                             2025-29: Bulk food production
                                                                                                                             systems

                                                                                                                             2025-29: Biological engineering
                                                                                                                             for food production

electromechanical devices (valves, pumps, centrif-                                gaseous contaminant release (e.g., ammonia). Re-
ugal gas/liquid separators, etc.) and “static” ma-                                covered potable water must be disinfected to en-
terials (sorbents, catalysts, membranes, etc). The                                sure safe storage with biocides that don’t pose
physical, chemical, and microbiological complex-                                  long-term crew member health risks. The capa-
ity and variability of wastewaters necessitate that                               bility to recover water from a wider range of po-
they be stabilized to protect equipment from bi-                                  tential wastewater sources can contribute to low-
ological and chemical fouling-induced failure and                                 er life-cycle costs, particularly by enabling clothes

                                                                         DRAFT                                                                          TA06-9
laundering and reducing dependence on expend-            food packaging via new materials, bulk food prep-
able wipes for crew hygiene.                             aration, and on-orbit food production capabilities
   Solid waste management systems for missions to        is also required for future missions. Advances in
date have been limited to a “cradle-to-grave” ap-        biology have the potential to revolutionize food
proach, consisting of a one-time use of supplies         production in space through genetic engineering
followed by storage and return to Earth. Beyond          of plants to increase harvest index, protein and vi-
hand compression of trash prior to containment,          tamin content, and growth rate, and create short-
no processing is conducted. Biological growth and        er, more volume-efficient crops. A key challenge
concomitant odor production continue during              for food production will be developing energy-ef-
storage, and are managed using closed or vented          ficient lighting technologies, including electrical-
storage containment. While this strategy has suf-        ly driven devices such as Light-Emitting Diodes
ficed for past missions, including frequent down-        (LEDs) or the use of captured solar light.
mass return to Earth, it will not satisfy the require-     Hygiene systems include partial-body cleaning
ments of future long-duration missions.                  (hand washing, wipes), full-body cleansing (show-
   Enabling long-duration missions will require es-      ers), and metabolic waste collection interfaces (fe-
tablishing an integrated “cradle-to-cradle” strat-       cal, urine, menstrual, emesis). Urine pretreatment
egy that employs resource retrieval and reuse via        and hygiene cleansers/chemicals must be com-
water recovery, air revitalization, and other sub-       patible with water recovery technologies, and the
systems. Further gains can be realized by deliber-       human waste collection interface must facilitate
ate selection of mission consumables, packaging          processing and stabilization of feces. Necessary
plastics, and spacecraft materials that facilitate di-   housekeeping improvements include trash/de-
rect reuse or serve as feedstock for in-situ man-        bris collection, surface cleaning systems, advanced
ufacturing of valuable products such as radiation        consumables stowage (packaging material devel-
protection, spares and fuel. Such processing will,       opment), antimicrobial/antiseptic recovery con-
by default, 1) provide mass and volume savings;          trol, and post-fire cleanup.
2) enhance mission sustainability; and 3) reduce           Deep-space missions will require the ability to
the amount of waste that requires safe handling,         launder clothing in space. Both body hygiene and
storage and disposal. Extensive waste reuse also         laundry typically utilize water and a cleaning sur-
decreases the amount of waste that requires pro-         factant to remove salts, body oils, and dander. Re-
cessing to satisfy potentially restrictive planetary     covery of this high Total Organic Carbon (TOC)
protection requirements. Widespread use of spe-          wastewater is important to closing the water bal-
cifically-designed biodegradable materials, includ-      ance. A laundry system that requires minimal sur-
ing bioplastics, can dramatically increase resource      factants to clean clothing is desirable. Addition-
recovery and reduce residue proportions.                 al key challenges include developing light-weight,
   Habitation engineering is a distinct TA directly      quick-dry fabrics for crew clothing and repeated-
applicable to vehicle success, but an area that his-     use antimicrobial wipes that require only negligi-
torically has been inadequately addressed in initial     ble cleaning.
vehicle system design. Current habitation capabil-         Re-purposing of stowage containers has been
ities were designed for LEO missions and are not         proposed to minimize mass and allow reuse via
optimized for resupply, reliability, mass, volume,       conversion into crew items and acoustic/radiation
and autonomy requirements which will be design           blankets. Alternate approaches include reduction
drivers for deep-space missions.                         in volume for disposal, or conversion to solid plas-
   Habitation cleaning, clothing, and consumables        tic bricks by heat melt compaction for use as radi-
are currently all open-loop systems, and portions        ation shielding.
of the loops must be closed for long-duration mis-         The major challenges of each sub-element, as
sions beyond LEO. Several habitation systems             well as efforts required to overcome the challeng-
have considerable interface with Air Revitaliza-         es to develop and demonstrate the technology to
tion, Waste Management, and Water Recovery               TRL-6, are listed in Table 2.
systems, and require improved capabilities as stat-      2.2. Extra-Vehicular Activity (EVA)
ed in the paragraphs below. Other habitation sys-               Systems
tems are detailed in TA07, HEDS.                           EVA systems are critical to every foreseeable hu-
   Improved means of food preparation, rehydra-          man exploration mission for in-space microgravity
tion, water dispensing, and galley architecture          EVA and for planetary surface exploration. In ad-
concepts are needed. A significant reduction of

TA06-10                                           DRAFT
dition, a Launch, Entry and Abort (LEA) suit sys-                       tems to supply data to enable crew members to
tem is needed to protect the crew during launch,                        perform their tasks with more autonomy and ef-
landing and cabin contamination/depressuriza-                           ficiency.
tion events. An EVA system includes software and                        2.2.1. Approach and Major Challenges
hardware that spans multiple assets in a given mis-                       The current suit development process is ham-
sion architecture and interfaces with many vehicle                      pered by a lack of analytical modeling to predict
systems, such as life support, power, communica-                        combined body-suit dynamics, effects of body pa-
tions, avionics, robotics, materials, pressure sys-                     rameters, and suit size. A high-fidelity integrat-
tems, and thermal systems. AIAA publications ,                  5,6,7

                                                                        ed model will allow computer simulations lead-
provide further details of the current SOA of the                       ing to decreased development time and cost while
EVA technology and challenges necessary to ad-                          providing better-performing suits. This capability
vance this TA to conduct NASA’s planned mis-                            could also potentially lead to preventing crew in-
sions safely, affordably, and sustainably. The com-                     jury during mission phases that require suited op-
plete EVA system includes three functions, each of                      erations.
which is described below.                                                 Extending these capabilities to include the abili-
  Pressure Garment – The suit, or pressure gar-                         ty to model the LEA suit-seat interface and predict
ment, is the set of components a crew member                            crew injuries during vehicle landing will enhance
wears and uses. It includes the torso, arms, legs,                      crew safety and survivability. New suit materi-
gloves, joint bearings, helmet, and boots. The suit                     als could potentially perform multiple functions
employs a complex system of soft-goods mobility                         that may include power generation, heat rejec-
elements in the shoulders, arms, hips, legs, torso,                     tion, communication, dust protection, injury pro-
boots, and gloves to optimize performance while                         tection, reduced risk of electrical shock hazards
pressurized without inhibiting unpressurized op-                        (e.g., due to plasma charging), radiation protec-
erations. The LEA suit also contains provisions to                      tion, and enhanced crew survivability. New mate-
protect the crew member from both the nominal                           rials should continually be identified, evaluated in
and off-nominal environments (e.g., gravitational,                      coupon-level testing, and then integrated into suit
sound, chemical) encountered during launch, en-                         components. Once they have been proven as a via-
try and landing.                                                        ble, effective suit component via a pressurized suit
  Portable Life Support System (PLSS) – The                             test in a relevant environment, they will be con-
PLSS performs functions required to keep a crew                         sidered TRL-6. Advanced suit tests in the Neu-
member alive during an EVA. These functions in-                         tral Buoyancy Laboratory (NBL) at JSC are an ap-
clude maintaining thermal control of the astro-                         propriate environment for microgravity mobility
naut, providing a pressurized oxygen environ-                           evaluations. Other reduced-gravity testing simula-
ment, and removing products of metabolic output                         tors exist and can be used when appropriate. Vac-
such as CO2 and H2O.                                                    uum chamber tests may also be relevant environ-
  Power, Avionics, and Software (PAS) – The                             ments for suit demonstrations of concepts that use
PAS system is responsible for power supply and                          advanced materials. These innovations should lead
distribution for the EVA system, collecting and                         to game-changing suit configurations and archi-
transferring several types of data to and from oth-                     tectures with decreased mass, improved mobility,
er mission assets, providing avionics hardware to                       self-sizing capabilities, and/or increased life. Im-
perform numerous data display and in-suit pro-                          proved materials may also lead to advances in mo-
cessing functions, and furnishing information sys-                      bility elements such as gloves, shoulders, bearings,
5          Chullen, C., and Westheimer, David T., 2010, “Extravehic-    and other joints.
ular Activity Technology Needs.” Paper presented at AIAA Space 2010       LEA suits could benefit from many of these
Conference, Anaheim, California, August 30-September 2.                 types of advances in suit materials. They could
6          Conger, B., Chullen, C., Barnes, B., Leavitt, G., 2010,      be donned extremely quickly in the event of an
“Proposed Schematic for an Advanced Development Lunar Portable          emergency, which could provide crew protection
Life Support System (AIAA-2010-6038).” Paper presented at 40th In-      for more vehicle failure scenarios. Integrated crew-
ternational Conference on Environmental Systems, Barcelona, Spain,
July 11-15.
                                                                        escape or crew-survival hardware would be benefi-
7          Malarik, D., Carek, D., Manzo, M., Camperchioli, W.,         cial as well. New designs that better integrate the
Hunter, G., Lichter, M. and Downey, A., 2006, “Concepts for Ad-         suit, restraints, supports, and the vehicle seat could
vanced Extravehicular Activity Systems to Support NASA's Vision for     greatly increase the safety of crew members. Tech-
Space Exploration (AIAA-2006-348).” Paper presented at 44th AIAA        nology solutions to enable long-duration suited
Aerospace Sciences Meeting and Exhibit, Reno, Nevada, January 9-12.

                                                               DRAFT                                                  TA06-11
operations, as in the case of a cabin depressuriza-     of an integrated PLSS on ISS provides the ulti-
tion event, could resolve technical challenges as-      mate validation of a microgravity suit.
sociated with long-duration waste management,             PAS has significant opportunities to realize dra-
provision of food and water, and administering          matic increases in capabilities over the current
medication. Emergency breathing systems incor-          SOA. Key hardware constraints include mass,
porating oxygen generation, rebreathers, or filtra-     power, volume, and performance of existing ra-
tion systems would be beneficial for emergency          diation-hardened electronics. As such, there are
scenarios with smoke or the release of toxic chem-      many dependencies on other TASRs. For example,
icals.                                                  significantly increased bandwidth and processing
  The PLSS is a prime candidate for infusion of         requirements will exist for communications sys-
new technologies to significantly reduce consum-        tems. These will include a radio with networking
ables, improve reliability, and increase crew per-      capabilities and data rates that support the trans-
formance. Regenerable technologies for removing         mission of high-definition (HD) video. Integrat-
moisture and CO2 from the suit lead to reduced          ing speakers and microphones into the suit will
consumables and mass requirements. Amine swing          improve crew comfort and the reliability of the
bed technology, currently being developed, can be       communications system. Information systems and
proven via a test on ISS in the 2016 timeframe.         displays have tremendous possibilities for greatly
Additional advances could include the ability to        improving crew autonomy and efficiency, and ad-
capture CO2 and moisture from the suit, and de-         vancing the SOA. The future caution and warning
liver them back to the vehicle without incurring        system will have to obtain, process, and visually
significant mass, volume, or power penalties. This      display the affected crew member’s individual cau-
would help close the loop for water and oxygen          tion and warning telemetry, and that of other crew
on a mission level. These advances could be made        members. An integrated sensor suite including
with technologies such as zeolites, nano-porous         crew health diagnostics, coupled with advanced
beds, or wash-coated foams. The crew member             informatics, speech recognition, voice command-
is cooled using a water loop that passes through        ing, computing and display systems, can offer a
a liquid cooling garment and also an evaporative        wealth of information on crew state, external en-
cooling device that vents to a space vacuum. Inno-      vironment, mission tasks, and other mission-crit-
vations to make this water loop robust to chem-         ical information to maximize crew performance
ical, particulate, or microbial contamination are       and safety. Also, dramatic increases in the specif-
critical to providing reliable, long-lasting systems.   ic energy of future power systems are needed. PAS
In addition, non-venting heat rejection technol-        system demonstrations should be performed to
ogies would lead to significant reduction in mis-       mature selected technologies. An initial demon-
sion consumables. Compact, low-mass, reliable,          stration needs to be performed around 2016 to
and efficient technologies need to be developed         support EVA flight demonstrations and validate
that can reject heat to the spectrum of thermal         the maturity of technologies that could be used
environments of expected exploration missions. A        to support future ISS EVA activities. Additional
variable set-point oxygen pressure regulator would      demonstrations on ISS in the 2020-25 timeframe
provide new capabilities to decrease pre-breathe        need to be performed to show that technologies
time, treat in-suit decompression sickness, and in-     can provide the crew with the autonomy needed
terface with a wide number of vehicles that may         to perform missions farther and farther away from
operate at different atmospheric pressures. Opti-       Earth.
mization of inhalation/exhalation/ventilation ar-         The major technical challenges for each sub-el-
chitecture could provide potential benefits for         ement, as well as efforts required to overcome the
umbilical-based EVA scenarios. Because the PLSS         challenges to develop and demonstrate the tech-
is such a highly integrated system, it is necessary     nology to TRL-6, are listed in the following text
to perform system demonstrations to evaluate the        and summarized in Table 3.
combined performance of advanced technolo-              2.3. Human Health and Performance
gies. A PLSS human vacuum chamber test will be                 (HHP)
needed to bring technologies to a maturity level          The main objective of the HHP technologies is
that allows for a flight demonstration in the 2016      to maintain the health of the crew and support
time frame. Another PLSS vacuum chamber test            optimal and sustained performance throughout
should be performed to evaluate the technologies        the duration of a mission. The HHP domain in-
developed to reduce PLSS consumables. Testing

TA06-12                                          DRAFT
Table 3. EVA Systems Technical Area Details
                   Technology                Current SOA/Practice                        Major Challenge(s)                                 Recommended Milestones/
Element
                                                                                                                                            Activities to Advance to
                                                                                                                                            TRL-6 or beyond
Sub-

                   Multifunctional suit      Suits comprised of multiple layers of       Materials that can serve multiple functions        2013: coupon-level demo
                   materials development     materials that independently provide        including eliminating suit-induced injury,
                                             functions such as structural support,       protecting from electric shock, saving mass,       2020: suit-level capability
                                             thermal insulation, or atmosphere           and improving suit mobility
                                             containment                                                                                    2025: multifunctional materi-
                                                                                                                                            als with increased capabilities
                   Suit modeling tool        No integrated modeling capability           Optimize suit design using combined body           2013: initial capability
                   development               exists to evaluate suit sizing, mobility,   and suit modeling to predict dynamic inter-
                                             or human-suit kinetics                      actions between the limbs and the suit             2018: validated model

                                             Tests with human subjects and their         Provide capability to evaluate multiple suit
                                             qualitative assessment is used              architectures prior to finalizing design and
                                                                                         fabrication
Pressure Garment

                   Improved suit-seat        Crew members are restrained in their        Develop options for restraining and protect-       2015: Integrated suit-seat
                   interface design          seats with a harness that is applied        ing crew members during violently dynamic          demo
                                             over the suit                               mission events

                                             Personal aviation and auto racing
                                             industry advances have not yet been
                                             incorporated into space applications
                   On-back regener-          Suits use Lithium Hydroxide (LiOH),         In–situ regenerable technologies that will         2014: TRL-6 component
                   able CO2 and humidity     which is not regenerable, or Metal          allow on-back regeneration and enable              demo
                   control                                                               sustained EVA
                                             Oxides, which are heavy and require a                                                          2020: CO2/H2O capture for
                                             power intensive bake-out                                                                       in-vehicle recovery
                   Closed-loop heat rejec-   Water evaporation is vented to space        Heat rejection systems with no consumables         2020: component ground
                   tion system with zero     – for missions with many EVAs this is       to eliminate water loss for cooling and            demo
                   consumables               a significant impact to the vehicle life    decrease total mission mass
                                             support system                                                                                 2025: PLSS demo
                   Variable Set-point Oxy-   Suit pressure regulators have two           Capability to treat decompression sickness         2015: component ground
                   gen Pressure Regulator    mechanically-controlled set points          in the suit, allow for rapid vehicle egress,       demo
                                                                                         and provide flexibility for interfacing the suit
PLSS

                                                                                         with multiple vehicles that may operate at
                                                                                         different pressures
                   Miniaturized Electronic   Suits use limited electronics               New techniques to miniaturize electronics          2015: subsystem capability
                   Components Demon-                                                     that enable decreased on-back mass while
                   strated                                                               increasing the performance of suit avionics        2020: system capability demo

                                                                                         Components need to be radiation-hardened
                                                                                         or radiation-tolerant and cost-effective to
                                                                                         produce
                   Advanced Displays and     Laminated data sheets and voice com-        Enhanced on-suit displays, tactile data entry,     2020: helmet display
                   Enhanced Information      munications from the ground or IVA          voice commanding, integrated sensors suite,
                   Systems                   crew members                                and on-suit systems to optimize crew perfor-       2025: information system
                                                                                         mance, mission planning, and system control
                                                                                         based on telemetry
                   On-suit Power Systems     The silver-zinc battery provides ap-        Low-mass, high-capacity energy storage to          2016: battery demo
                                             proximately 70 Wh/kg                        meet EVA power and mass budgets (1,100
                                                                                         Wh with less than 5 kg of mass ( > 220 Wh/         2025: advanced power
PAS

                                                                                         kg))                                               system

cludes four functional focus areas as shown below.                                           Behavioral Health and Performance – The ob-
  Medical Diagnosis/Prognosis – The objective                                              jective in this topical area is to provide technol-
of this functional area is to provide advanced med-                                        ogies to reduce the risk associated with extend-
ical screening technologies for individuals select-                                        ed space travel and return to Earth. Technology
ed to the astronaut corps and prior to crew selec-                                         advancements are needed for assessment, over-
tions for specific missions; this is a primary and                                         all prevention, and treatment to preclude and/or
resource-effective means to ensure crew health.                                            manage deleterious outcomes as mission duration
  Long-Duration Health – The focus here is pro-                                            extends beyond six months.
viding validated technologies for medical practice                                           Human Factors and Performance – This el-
to address the effects of the space environment on                                         ement focuses on technologies to support the
human systems. Critical elements include research                                          crew’s ability to effectively, reliably and safely in-
and testing, including innovative use of test plat-                                        teract within the mission environments. Elements
forms such as Biosentinels and micro and nano                                              here include user interfaces, physical and cogni-
satellites, and the development of countermea-                                             tive augmentation, training, and Human-Systems
sures for many body systems.                                                               Integration (HSI) tools, metrics, methods and
                                                                                           standards.
                                                                                    DRAFT                                                                         TA06-13
2.3.1. Approach and Major Challenges                   and nano satellites (Edison) and Commercial or
  Future human spaceflight exploration objectives      International collaborative missions such as Bions.
will present significant new challenges to crew          Missions beyond LEO will pose significant chal-
health, including hazards created by traversing the    lenges to astronauts’ psychological health, includ-
terrain of planetary surfaces during exploration       ing confined living quarters with a small crew,
and the physiological effects of variable gravity      delayed communications, no view of Earth, and
environments. The limited communications with          separation from loved ones. Potential deleteri-
ground-based personnel for diagnosis and con-          ous outcomes associated with these risk factors
sultation of medical events will create addition-      increase as mission duration extends beyond six
al challenges. Providing healthcare capabilities for   months; nonetheless, some missions may last up
exploration missions will require definition of new    to three years. Additional technologies are need-
medical requirements and development of tech-          ed to identify, characterize, and prevent or reduce
nologies; these capabilities will help to ensure Ex-   BHP risks associated with space travel, explora-
ploration mission safety and success before, dur-      tion, and return to terrestrial life. These technol-
ing, and after flight.                                 ogies include 1) prevention technologies like reli-
  Medical systems for Exploration missions will        able, unobtrusive tools that detect biomarkers of
be pursued based on spaceflight medical evidence       vulnerabilities and/or resiliencies to help inform
generated to date, as well as research and analog      selection recommendations; 2) assessment tech-
populations. For each Exploration DRM, a list of       nologies for in-flight conditions such as high CO2
medical conditions that have high likelihood and/      levels, high air pressure, noise, microgravity, and
or high crew health consequences to mission suc-       radiation that may exacerbate risk; and 3) counter-
cess will be generated. Astronauts currently un-       measures aimed to prevent behavioral health dec-
dergo medical screening before they are selected       rements, psychosocial maladaptation, and sleep
to the astronaut corps and before they are chosen      and performance decrements; also, countermea-
for specific missions. This is currently the prima-    sures aimed to treat if decrements are manifested.
ry, and most resource-effective, means to ensure         A successful human spaceflight program heavily
crew health.                                           depends on the crew’s ability to effectively, reliably
  The on-going progress made in the field of ge-       and safely interact with their environments. HFP
nomics, proteomics (protein), metabolomics (me-        represents a commitment to effective, efficient, us-
tabolites), imaging, advanced computing and in-        able, adaptable, and evolvable systems to achieve
terfaces, microfluidics, intracellular Nanobots for    mission success, based on fundamental advances
diagnosis and treatment, materials, and other rel-     in understanding human performance (percep-
evant technologies will significantly enhance ad-      tion, cognition, action) and human capabilities
dressing the medical needs of the human system.        and constraints in context. The most critical el-
  Maintenance of HHP will require research be-         ements of the HFP roadmap are 1) user interfac-
fore and during flight. A number of proposed           es such as multimodal interfaces and advanced vi-
technologies align with today’s Medical Progno-        sualization technologies; 2) physical and cognitive
sis Team items and can be transitioned to medi-        augmentation such as adaptive automation based
cal practice once they have been fully validated.      on in-situ monitoring of work activity; 3) training
Other cross-cutting technologies provide signifi-      methods/interfaces; and 4) Human-Systems Inte-
cant value to other discipline teams – one exam-       gration (HSI) tools, metrics, methods and stan-
ple is artificial gravity, which is seen as a poten-   dards, such as those being developed by other gov-
tial game-changing technology. Aside from being        ernment agencies, NASA HSI assessment tools,
a promising countermeasure for many body sys-          and human performance tools such as the devel-
tems, development would require a new approach         opment of human readiness level and related con-
to vehicle design and potentially revolutionize the    cepts for fitness-for-duty.
way we explore space. The effect of microgravi-          Table 4 identifies the essential function/technol-
ty and radiation on human systems will be ascer-       ogy relevant to the four sub-elements identified,
tained using model systems (Biosentinels) such as      current SOA/practice for the near-term planned
cells, 3D-tissue, micro-organisms and small ani-       missions, major challenges to mature the technol-
mals and these model systems will be evaluated         ogy and the potential development activity need-
using robotic precursor missions with platforms        ed for future missions and the time-line to elevate
(including altered-gravity capabilities) planned at    the potential technology, as envisioned today, to
ISS, free-flyer-hosted payloads including micro        TRL-6.

TA06-14                                         DRAFT
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