Digital therapies How can the healthcare system change? 1/2020 - Earlybird Venture Capital

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Digital therapies How can the healthcare system change? 1/2020 - Earlybird Venture Capital
14th issueu | Spring Edition | Volume 7               1/2020

                                              Interview
                                              Thom Rasche,
                                              Earlybird
                                              Venture Capital

                                              Event
                                              MedTech Radar
                                              LIVE 2020 in Köln

                   Digital therapies
                   How can the healthcare
                   system change?

A cooperation of
Digital therapies How can the healthcare system change? 1/2020 - Earlybird Venture Capital
¤   Focus: Digital therapies

    Digital Therapies

    How can the system change?
    MedTech Radar LIVE 2020 on 9th June looks at the digital change taking place in healthcare
    with examples from the fields of diabetology, cardiology and endoprosthetics. What should
    Medtech firms and start-ups do in order to stay in the game?

    M
                 edical products such as pacemakers,       evidence-based medicine – it is all about making
                 insulin pumps and joint implants are      decisions based on real-life data. Digital solutions
                 already playing an important role in      mean that these data are increasingly easy to coll-
    healthcare. At the same time, continued advance-       ect and analyse”, explains Thom Rasche, Managing
    ments in digitalisation, miniaturisation, artificial   Partner at Early Venture Capital. He believes that
    intelligence (AI) and sensor technology indicate       as these developments continue, the focus will
    that the next generation of medical products is on     shift more towards looking at the overall clinical
    the horizon. “Many conditions related to cardiol-      picture and establishing holistic cross-sector mo-
    ogy, endoprosthetics and diabetes require complex      dels for healthcare delivery instead of the current
    therapies that extend throughout an individual’s       method focused on individual medical products or
    lifetime. In these cases, digital solutions can pro-   drugs. “We need to look more at the overall clini-
    vide real improvements and offer patients more         cal picture”, stresses Rasche in an interview (see
    ownership over their treatment” says Anke Cass-        page 36).
    ing, investment manager at the fund management
    company High-Tech Gründerfonds.                        Digital models of healthcare provision, cer-
                                                                                                                  Abb.: BVMed/BIOTRONIK

                                                           tainly– but how?
    Individual patient needs are playing an increasin-     How such models could look like in the future
    gly central role – even more so if medical products    will be discussed at MedTech Radar LIVE 2020 on
    are reimbursed. “Whether value-based care or           June 9th in Cologne. Discussions will focus on the

    2 MEDTECH RADAR – 1/2020
Digital therapies How can the healthcare system change? 1/2020 - Earlybird Venture Capital
Focus: Digital therapies   ¤

challenges associated with digital medicine in the     products important to the Medtech sector”, says
fields of cardiology, diabetes and endoprosthetics.    Möll. The association is also advocating openness
Using specific examples, established businesses        towards higher-risk digital medical products. In-
from the medical technology and pharmaceutical         vestors such as HTGF also feel that further discus-
industries, clinicians and selected start-ups will     sions are needed regarding specific routes to imple-
all come together with investors and representa-       mentation. “Introducing digital solutions requires
                                                       changes throughout the entire healthcare system
                                                       that have so far been only partially implemented.
   SMEs und start-ups can more easily                  The DVG legislation still has room for improvement”,
                                                       says HTGF’s Anke Cassing. She believes that new
   apply locally adapted digital solu-
                                                       models for cooperation between the various stake-
   tions than larger corporates.                       holders are needed. “Collaboration between start-
                                                       ups, Medtech firms and service providers must be
tives from health insurance providers to discuss       strengthened to expedite the entry of useful solu-
promising new healthcare solutions in these fields     tions to the market. As an investor we are looking
and identify the possibilities associated with         for established medical technology companies that
digitalisation and the challenges that will arise      are willing to work with start-ups.”            ¤
during the practical implementation.

“Many of our member companies are global pro-            MedTech Radar LIVE 2020
 viders of medical technologies, who at the same
 time, have to apply digital healthcare solutions        9th June, Cologne
 within very specific local contexts. This balanc-
 ing act of global and local perspectives must be
 tackled – both within the companies, as well as         MedTech in transition -
 with a view to possible funding models”, says           Where is digital medicine heading?
 Marc-Pierre Möll, managing director of the Ger-
 man medical technology association BVMed.               The event, organised by BVMed in cooperation
 Thom Rasche believes that this situation can            with medtech zwo, Earlybird Venture Capital
 result in a competitive advantage for SMEs and          and High-Tech Gründerfonds, will discuss
 start-ups. According to the investor: “Wherever         digital healthcare in the areas of diabetology,
 possible they can more easily apply solutions that      cardiology and endoprosthetics with repre-
 are adapted to local requirements and integrate         sentatives from industry, start-ups, clinical
 them into national reimbursement systems,               professionals, health insurance providers and
 which is not easily applicable with the structures      investors.
 of large, global organisations”.
                                                         How can start-ups get involved?
The DVG as a driver – but there is
room for improvement                                     Start-ups offering digital solutions in diabetol-
The speed at which the new German Digital Care           ogy, cardiology or endoprosthetics can apply
Act (“Digitale-Versorgung-Gesetz”, DVG) is being im-     to participate until the end of April. Five teams
plemented has been well received. Experts expect         in each of the application areas will receive a
that by mid 2020, the processes for funding digital      place at the exhibition. The two best teams in
healthcare applications will be in place. “We are,       each field will take part in the main event.
however, critical of the significant requirements
and costs of demonstrating the positive effects of       More info: www.medtechradar.live
these solutions, as well as the lack of combination

                                                                                MEDTECH RADAR – 1/2020       3
¤   Focus: Digital therapies

    Investor Perspective

    „We need to look more at the
    overall clinical picture “
    How should the sector position itself in order to implement digital therapies in
    practice? For Thom Rasche, Earlybird Venture Capital, one thing is clear: In the
    future, we must focus more on illnesses and patients rather than on products.

    MEDTECH RADAR | Mr Rasche, what possibilities
    do digital therapies offer?

    Thom Rasche | They open up the possibility for all
    businesses in the healthcare sector, whether medical
    technology firms, pharmaceutical firms or start-ups,
    to get much closer to patients in the future. This re-
    presents a complete paradigm shift. To date, compa-
    nies have just been the suppliers who only indirectly
    communicate with customers and patients. This is
    all changing, however, with the introduction of digi-
    tal solutions and possibilities

    MEDTECH RADAR | Why it‘s important to be close
                                                                 é
    to patients? Why should companies strive to do this?
                                                                   Thom Rasche works with the VC investor Ear-
    Thom Rasche | I think it is important for a variety            lybird Venture Capital since 2003. Since 2015,
    of reasons. Regulatory authorities and health insu-            he is active as Managing Partner.
    rance providers are increasingly expecting data that
    shows how patients are using medical products and
    medicines. The term “compliance” is also relevant
    here: What effects are my products having on the
    daily life of patients, what interactions are there with    just the right amount of insulin as needed. Whilst
    other medications or therapies? In the future, know-        this scenario is certainly not possible for all diabetic
    ledge such as this will go into the process of deciding     patients, it demonstrates the kinds of technological
    whether something should be funded.                         developments we can expect.

    The good thing here is: Digital solutions can be used       MEDTECH RADAR | This will bring about entirely
                                                                                                                           Abb.: Earlybird Venture Capital

    to collect this type of real-life data and be used as the   new disease management systems. What other pos-
    basis for entirely novel disease management sys-            sibilities exist in other areas?
    tems, such as in diabetology for example. Imagine an
    artificial pancreas with integrated insulin pump that       Thom Rasche | Further interesting scenarios for di-
    automatically measures insulin levels and injects           gital models of healthcare can be seen in cardiology.

    4   MEDTECH RADAR – 1/2020
Focus: Digital therapiea   ¤

For example, think about remotely monitoring pa-          Thom Rasche | We need innovations that look at
tients with pacemakers. Real time monitoring and          the treatment pathway and course of the disease,
emergency responses are possible.                         rather than just looking at specific parts. There are
                                                          many ideas, but the main question is: How can the-
The question here is simply: Who will take on the re-     se business models be implemented?
sponsibility? Should it be the patient’s GP react? We
might even see more reliance on external service          MEDTECH RADAR | What is the greatest challenge
providers that collect patient data, evaluate this data   that needs to be tackled?
and make it available to doctors in a structured for-
mat. The central question is: Within a digitally sup-     Thom Rasche | We need data that is not sourced
ported infrastructure, who takes care of the patient      from clinical studies, i.e. data from the day-to-
and who is liable for what? There are no clear answers    day provision of healthcare, that can demonstrate
currently, and that’s precisely why we need to start      these approaches. This is the only way to effec-
talking about it. The next MedTech Radar LIVE event       tively identify the economic benefits of holistic
on the 9th of June in Cologne will provide a forum for    models of healthcare provision.
this discussion.
                                                          The question here is: In the future, who needs to
MEDTECH RADAR | Alongside diabetology and car-            work together with whom? And how do funding
diology, what other examples of digital therapies will    systems need to be adapted so that specific ser-
be discussed?                                             vice packages containing products and the pro-
                                                          vision of healthcare itself can be paid for across
Thom Rasche | We have decided on the field of en-         multiple sectors? Which business models are best
doprosthetics. This is a field in which new sensor        for the companies involved and how can profita-
technologies offer new options for direct monito-         bility be determined? How can global companies
ring of implants and carrying out motion analysis.        manage to integrate themselves into local health-
Entirely new models for providing care can also be        care structures? We still have the situation that
developed if we make the patient central to our con-      medical products and medicines are used glo-
siderations.                                              bally, but the actual provision of these to patients
                                                          takes place at the national, regional and local le-
MEDTECH RADAR | How could this look in practi-            vels.
ce?
                                                          MEDTECH RADAR | Do you feel that the sector is
Thom Rasche | It has been shown, for example, that        ready to face this challenge?
patients having hip operations spend less time in
the hospital if they are first prepared for the ope-      Thom Rasche | Some stakeholders may be ready, but
ration using certain physiotherapeutic procedures         most are not. That is why events like MedTech Ra-
and receive a tailored rehabilitation programme           dar LIVE are important for raising awareness of the
immediately afterwards. Why then, should implant          problem. We are currently seeing plenty of dyna-
manufacturers not concern themselves with pre             mism within the digital sector in Germany, which
and post-operative treatment in the future? There         is being partly driven by digital healthcare legislati-
is currently too much focus on the product itself. I      on. It is therefore the perfect time to talk about how
am convinced, however, that we must start looking         things need to develop moving forward. I feel that
at the overall clinical picture and less at individual    all stakeholders within the healthcare business
end products.                                             need to work together more: Medical technology
                                                          companies, pharmaceutical companies, start-ups,
MEDTECH RADAR | What technologies and inno-               insurance providers and hospitals. The boundaries
vations are needed in this regard?                        are not clear.                                      ¤

                                                                                    MEDTECH RADAR – 1/2020      5
¤   Focus: Digital heatlhcare

      The MedTech Radar is a joint information serv-         The High-Tech Gründerfonds, an initiative of the
      ice of HTGF, Earlybird, BVMed and medtech zwo.         Federal Ministry for Economic Affairs and Energy,
      It offers insights into current trends of medical      the KfW, Fraunhofer Society and 32 companies,
      technology sector. The publication is published        supports young technology companies with seed
      twice a year in spring and autumn.                     financing to advance research projects at least
                                                             until a prototype status or until market entry.
      The MedTech Radar is available as PDF down-
      load in German and English at the websites of
      the partners. The German issue is an additional        Contact: High-Tech Gründerfonds
      part of the medtech business journal “medtech          Management GmbH | Cornelia Mann |
      zwo” published by BIOCOM AG twice a year in            Tel.: +49 228 823 00 121 c.mann@htgf.de |
      spring and autumn.                                     www.high-tech-gruenderfonds.de

      Earlybird is a European venture capital inves-
      tor with an experienced team of health experts         As an information specialist, BIOCOM AG has
      focused on investing in early European technology      supported the life sciences with journals, web-
      companies in the health tech area.                     sites, books and videos for more than 30 years.
                                                             The magazine medtech zwo reports on recent
                                                             developments relating to the medtech sectors of
      Contact: Earlybird Venture Capital                     Germany, Austria and Switzerland.
      Catrin Schmidt | Tel.: +49 30 467 247 00
      catrin@earlybird.com | www.earlybird.com
                                                             Contact: medtech zwo | BIOCOM AG
                                                             Sandra Wirsching | Tel.: +49 30 264 921 63
                                                             s.wirsching@biocom.de
                                                             www.medtech-zwo.de | www.biocom.de

      The German Medical Technology Association
      (BVMed) is an industry association that represents   Imprint
      over 230 industrial and commercial companies in
      the medical technology sector. Among its members     Responsible for content according to i. S. d. P.
      are 20 of the largest medical device manufacturers   medtech zwo – BIOCOM AG, Lützowstr. 33–36, 10785 Berlin
      worldwide in the field of consumer goods.            BVMed – German Medical Technology Association,
                                                           Reinhardtstr. 29 b, 10117 Berlin
      Contact: BVMed | Manfred Beeres                      Earlybird Venture Capital – Münzstr. 21, 10178 Berlin
      Tel.: +49 30 246 255 20 | beeres@bvmed.de            High-Tech Gründerfonds Management GmbH –
      www.bvmed.de                                         Schlegelstr. 2, 53113 Bonn
                                                           Cover photo: sdecoret/stock.adobe.com

    6 MEDTECH RADAR – 2/2019
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