Caterina Buonocore, Health NCP, Coordinator of the "HNN3.0 NCP project" and Cluster 1 team, CL6
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Caterina Buonocore, Health NCP, Coordinator of the «HNN3.0 NCP project» and Cluster 1 team, CL6 buonocore@apre.it
Summary Health cluster : main structure , African perfomance EDCTP 3 : a longstanding collaboration EU- Sub saharan Africa
HEALTH RESEARCH
ERC
WHERE CAN YOU (Pillar I)
FIND IT? Pillar III MSCA
«Innovative
Europe» (Pillar I)
COMPLEMENTARITIES
WITH OTHER PILLARS Cluster 1
AND CLUSTERS Cluster 6 –
Health
Research
Food, (Pillar II) Infrastructure
bioeconom
(Pillar I)
y…
Cluster 4 – Cluster 3 –
Digital, Civil
Industry security for
and Space society
Complementarietà cross- Cluster 2 –
Inclusive
clusters con tutte le aree del society
2° Pilastro
Cluster 6 – Cluster 3 –
Alcuni esempi Food, Civil
CL 2. Ageing society ..inclusive society.. bioeconom Cluster 1 security for
CL 3. Cybersecurity of health data, protection of y… society
critical infrastructures, reaction to pandemics..
Improving response to domestic violence
CL 4. Robotics, Smart materials, training of
healthcare professionals, photonics..
CL6. Healthy Food and nutrition, … Cluster 4 –
Digital
Industry
and Space
WORK PROGRAMME “HEALTH” 2021-2024 6 Destinations 1. Staying Healthy in a rapid changing society 2. Living and working in a health-promoting environment 3. Tackling diseases and reducing disease burden 4. Ensuring access to innovative, sustainable and high-quality health care 5. Unlocking the full potential of new tools, technologies and digital solutions for a healthy society 6. Maintaining an innovative, sustainable and globally competitive health industry 12/09/2022 5
Horizon Europe – Cluster 1 “Health“
Calls for
Strategic Plan 2021-24 (link)* → 6 Expected Impacts proposals:
50%
Work Programme 2021-22 (link)*
6 “Destinations” → Topics (Calls)
1. Staying healthy in a rapidly changing society Focus on outcomes contributing to the
2. Living and working in a health-promoting impacts specified per Destination
environment
3. Tackling diseases & reducing disease burden Project proposals should
➢ make a clear case (value proposition)
4. Ensuring access to innovative, sustainable
➢ supported by a convincing trajectory
& high-quality healthcare
(pathway to impact) for the project
5. Unlocking the full potential of new tools, proposal to deliver the output, promote
technologies the outcome described in the topic, and
and digital solutions for a healthy society contribute to the impact expected under
6. Maintaining an innovative, sustainable & globally that destination.
competitive health industry
6
Impact statements/destinations of Cluster 1 ‘Health 1.Staying healthy in a rapidly changing society: Citizens of all ages stay healthy and independent in a rapidly changing society thanks to healthier lifestyles and behaviours, healthier diets, healthier environments, improved evidence-based health policies, and more effective solutions for health promotion and disease prevention. 2.Living and working in a health-promoting environment: Living and working environments are health-promoting and sustainable thanks to better understanding of environmental, occupational, social and economic determinants of health. 3. Tackling diseases and reducing disease burden: Health care providers are able to better tackle and manage diseases (infectious diseases, including poverty-related and neglected diseases, non-communicable and rare diseases) and reduce the disease burden on patients effectively thanks to better understanding and treatment of diseases, more effective and innovative health technologies, better ability and preparedness to manage epidemic outbreaks and improved patient safety. 4. Ensuring access to innovative, sustainable and high-quality health care: Health care systems provide equal access to innovative, sustainable and high-quality health care thanks to the development and uptake of safe, cost-effective and people-centred solutions, with a focus on population health, health systems resilience, as well as improved evidence-based health policies. 5. Unlocking the full potential of new tools, technologies and digital solutions for a healthy society: Health technologies, new tools and digital solutions are applied effectively thanks to their inclusive, secure and ethical development, delivery, integration and deployment in health policies and health and care systems. 6. Maintaining an innovative, sustainable and globally competitive health-related industry: EU health industry is innovative, sustainable and globally competitive thanks to improved up-take of breakthrough technologies and innovations, which makes the EU with its Member States more resilient and less dependent from imports with regard to the access to and supply of critical health technologies.
CLUSTER HEALTH | DESTINATION 1
Staying healthy in a rapidly
changing society
TOPICS 2022:
▪ Affronta le principali sfide sociali come l'obesità, ✓ Boosting mental health in Europe in times of
l'invecchiamento e il cambiamento demografico, change – RIA
la salute mentale, l’empowerment nell’ambito ✓ Trustworthy artificial intelligence (AI) tools to
della digital health literacy, la prevenzione predict the risk of chronic non-communicable
personalizzata e l'Intelligenza Artificiale applicata diseases and/or their progression – RIA
alle malattie croniche. ✓ Prevention of obesity throughout the life course –
▪ Progetti di ricerca e innovazione che RIA
forniscano nuove evidenze, metodologie e Deadline: 1 February /6 September 2022 – TWO-STAGE
strumenti per comprendere la transizione
dalla salute alla malattia. ✓ Personalised blueprint of chronic inflammation in
health-to-disease transition – RIA
Deadline: 21 April 2022 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 2
Living and working in
a health-promoting
environment*
▪ Comprendere gli impatti dell'inquinamento atmosferico TOPICS 2023:
indoor/outdoor, delle sostanze chimiche, dei campi HORIZON-HLTH-2023-ENVHLTH-02-01:
elettromagnetici, dell'urbanizzazione, del cambiamento Planetary health: understanding the links between
climatico e di altri cambiamenti ambientali, delle environmental degradation and health impacts
disuguaglianze socioeconomiche e del cambiamento degli
ambienti di lavoro.
▪ Rafforzare la capacità di adattamento e la resilienza delle
popolazioni e dei sistemi sanitari rispetto ai rischi per la
salute legati ai cambiamenti climatici e ambientali.
* Forte connessione con European Green Deal e Cluster 6, Mission Climate
CLUSTER HEALTH | DESTINATION 3
Tackling diseases
TOPICS 2022:
and reducing ✓ Pre-clinical development of the next generation of
disease burden* immunotherapies for diseases or disorders with unmet
medical needs - RIA
▪ Si concentra sulle principali sfide sociali come il cancro, le ✓ Vaccines 2.0 - developing the next generation of vaccines –
malattie non trasmissibili, le malattie rare, la resistenza RIA
✓ Development of new effective therapies for rare diseases –
antimicrobica, la vaccinazione e la preparazione alle
RIA
epidemie.
▪ Sviluppo di nuove misure di prevenzione, terapie e Scadenza: 1 Febbraio/6 Settembre 2022 – TWO-STAGE
tecnologie sanitarie innovative.
✓ Pandemic preparedness - RIA
✓ Non-communicable diseases risk reduction in adolescence
and youth (Global Alliance for Chronic Diseases - GACD) - RIA
✓ Support for the functioning of the Global Research
Collaboration for Infectious Disease Preparedness (GloPID-R)
* Complementare a Europe’s Beating Cancer
– CSA
Plan e EU4Health Programme ✓ European partnership fostering a European Research Area
(ERA) for health research – Placeholder – Programme Co-fund Action
Scadenza: 21 Aprile 2022 – SINGLE STAGECLUSTER HEALTH | DESTINATION 4
Ensuring access to innovative,
sustainable and high-quality
care*
▪ Sviluppo e adozione di soluzioni sicure, convenienti e TOPICS 2022:
incentrate sulle persone, con particolare attenzione alla ✓ Pre-commercial research and innovation procurement
salute della popolazione, alla resilienza dei sistemi sanitari (PCP) for building the resilience of health care systems
e alle politiche sanitarie basate sull'evidenza scientifica. in the context of recovery - PCP
▪ R&I per supportare i sistemi sanitari nella loro ✓ Public procurement of innovative solutions (PPI) for
trasformazione per garantire un accesso equo a building the resilience of health care systems in the
servizi sanitari sostenibili di alta qualità per tutti i context of recovery – PPI
cittadini. ✓ Better financing models for health systems – RIA
✓ European partnership on transforming health and care
systems – Programme Co-fund Action
* Forte sinergia con EU4Health Programme Deadline: 21 April 2022– SINGLE STAGECLUSTER HEALTH | DESTINATION 5
Unlocking the full potential of
new tools, technologies and TOPICS 2022:
digital solutions for a healthy ✓ Optimizing effectiveness in patients of existing
society* prescription drugs for major diseases (except
▪ Promuovere lo sviluppo di strumenti, tecnologie e cancer) with the use of biomarkers - RIA
soluzioni digitali per trattamenti, farmaci, ✓ New methods for the effective use of real-world
dispositivi medici, tenendo in considerazione data and/or synthetic data in regulatory decision-
sicurezza, efficacia, adeguatezza, accessibilità e making and/or in health technology assessment –
valore aggiunto. RIA
▪ I dati sanitari e gli strumenti analitici innovativi Deadline: 21 April 2022– SINGLE STAGE
vengono utilizzati in modo sicuro ed etico.
✓ Computational models for new patient
stratification strategies - RIA
* [!] European Health Data Space per promuovere lo
scambio di dati sanitari e la ricerca transfrontaliera. Deadline: 1 February/6 September 2022 – TWO-STAGECLUSTER HEALTH | DESTINATION 6
Maintaining an innovative,
sustainable and globally
competitive health industry*
▪ Adozione di tecnologie e innovazioni rivoluzionarie TOPICS 2022:
in grado di integrare gli attori della catena del ✓ Enhancing cybersecurity of connected medical devices -
valore. RIA
✓ Scaling up multi-party computation, data anonymisation
▪ L'industria sanitaria dell'UE è più competitiva,
techniques, and synthetic data generation – RIA
sostenibile e strategicamente autonoma. ✓ New pricing and payment models for cost-effective and
affordable health innovations – RIA
✓ Setting up a European Smart Health Innovation Hub –
CSA
✓ Setting up a European Electronic Health Record Exchange
Format (EEHRxF) Ecosystem - CSA
Scadenza : 21 Aprile 2022 – SINGLE STAGEFUTURE 2023-2024 : Remaining indicative timetable WP23-24 preparation Mid July 2022: ISC draft shared with PC Nov 2022: Formal consultation of Programme Committee configurations December 2022: Adoption of WP2023-2024 and publication WP23-24 implementation Mid-April 2023: deadline for single stage 2023 calls Mid-September 2023: deadline for 1st stage of 2-stage calls of 2024 Mid-April 2024: deadline for single stage 2024 calls and for 2nd stage of 2- stage calls of 2024
Cluster 1 Health | Success rate of African organizations: 11,7 % 238 Eligible applications 28 participations in funded projects
Health | Key Figures
Health | Top Funded Projects
Horizon Europe «Health» & Africa Some examples of Calls for proposals
Types of research EDCTP supports observation and interventional studies, with interventional trials making up the bulk of the EDCTP portfolio. We support phase I–III safety/efficacy studies, with an emphasis on phase II and III trials. We also support phase IV, pharmacovigilance and post-licensing effectiveness studies (pragmatic trials, utility/impact studies), product-focused implementation research and field trials, as well as trials of medical diagnostics to detect and monitor disease.
EDCTP3 Association | About membership http://www.edctp.org/about-us/governance/membership-edctp- association/
EDCTP3 | Important links • Funding and Tenders Portal link to the Global Health EDCTP3 topics • Global Health EDCTP3 (interim) website • Work programme text published on the Global Health EDCTP3 website • Research Enquiry Service | European Commission (europa.eu) • Open consultation for the AU-EU Innovation Agenda
EU Global Health Initiatives | Multi-lateral health research activities
Global Research Collaboration for Infectious Disease Preparedness
(GloPID-R)
▪ GloPID-R is a network of research funding
organizations in the area of infectious disease
preparedness research, aimed to facilitate an
effective research response of a new or re-emerging
infectious disease with epidemic and pandemic
potential, in order to save lives and economies
worldwide.
▪ GloPID-R has 32 members worldwide. The World
Health Organization, the Coalition for Epidemic
Preparedness Innovations (CEPI), the European &
Developing Countries Clinical Trials Partnership
(EDCTP) and ESSENCE on Health Research initiative are
also actively engaged in the network.
▪ HHS – Department of Health and Human Services (US)
▪ Bill and Melinda Gates Foundation (US)EU Global Health Initiatives | Multi-lateral health research activities
Global Research Collaboration for Infectious Disease Preparedness
(GloPID-R)
▪ GloPID-R is also
CHECK “RESOURCES”: current
actively involved in list of downloadable learning
systemic resources of funding
opportunities, webinars and
preparedness, publications, all of which
connecting clinical have been developed by
GloPID-R members
trial networks,
building a framework https://www.glopid-r.org/resources/
for data sharing and
improving the rapid
delivery of research
funding.EU Global Health Initiatives | Multi-lateral health research activities Global Alliance for Chronic Diseases (GACD) https://www.gacd.org/funding/current-call-for-applications
CHIEDI SUPPORTO AI TEAM TEMATICI IN APRE i www.horizon-europe.it
Email: buonocore@apre.it cluster1@pre.it Tel. +39 06 48 93 9993 www.apre.it
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