CALL FOR PAPERS PAPER SUBMISSION DEADLINE: FEBRUARY 18, 2021 - www.microscopy.orgMandM/2021 - Microscopy Society of America
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Questions? TECHNICAL MEETING CONTENT: Letter from the Presidents 2021 Program Chair Elizabeth Wright On behalf of the Microscopy Society of America and the Microanalysis University of Wisconsin-Madison Society, we invite you to join us, in-person, August 1-5, 2021, for Microscopy MM2021ProgramChair@microscopy.org & Microanalysis 2021 in Pittsburgh, PA. With a distinguished industrial history, Pittsburgh has transformed itself into a great summer destination with diverse, REGISTRATION: interesting and walkable neighborhoods. Combining comfortable temperatures Registrar in the 80s, with lots of outdoor and riverside activities, as well as a healthy pub MMRegistration@conferencemanagers.com and foodie culture, we know you will enjoy a great blend of science and social activities! At this time, MSA and MAS are planning to move forward with the EXHIBITS & EXHIBITORS: in-person meeting. However, in this age of COVID-19, there is uncertainty on Exhibits Manager the public health situation next year. If the conditions do not improve and we doreen@corcexpo.com are unable to meet in person, we plan to bring a vibrant and outstanding virtual meeting that builds off our experience from M&M 2020. We will create an even SPONSORS & SPONSORSHIPS: better virtual experience featuring platform and poster presentations, a robust Sponsorship Manager trade show experience, and opportunities to connect with old friends and make mary@corcexpo.com new friends. GENERAL: The Program Committee, led by Elizabeth Wright, Eric Stach, Vincent Meeting Manager Smentkowski, and Andrew Herzing, has developed an exciting group of meetingmanager@microscopy.org symposia, spanning advances in instrumentation and techniques development, as well as applications in the analytical, biological, and physical sciences. We encourage you to browse this Call for Papers for complete symposium Are You a Member? descriptions and to submit one or more scientific papers for platform or poster presentations. Tables will continue to be provided at the poster boards for fully Join Today and Save on M&M 2021 dynamic multimedia poster presentations. Registration Fees! The main meeting will be preceded by the ever-popular Sunday Short Courses and three Pre-Meeting Congresses. Students and early-career professionals are especially encouraged to participate in the MSA Student Council’s 5th Annual Pre-Meeting Congress that highlights outstanding work by student and Visit http://microscopy.org to join the postdoctoral fellow attendees. Join us Sunday evening to officially kick off the Microscopy Society of America online, or for meeting at the Opening Welcome Reception and reconnect with colleagues more information about the benefits of MSA and meet new friends. On Monday morning, the Plenary Session kicks off the membership. scientific program with an exciting set of lectures in Physical and Biological sciences and the presentations of the M&M meeting awards and awards from the sponsoring societies. In addition to the strong scientific program, what sets the M&M meeting apart Visit http://the-mas.org to find out the is the Exhibit Hall, the world’s largest annual microscopy exhibition, which benefits of MAS membership. showcases the latest instrumentation and accessories. Don’t miss the highly popular vendor tutorials, held Monday through Wednesday after hours in the Exhibit Hall. Other educational opportunities throughout the week include IMAGES: focused biological and physical science tutorials, educational outreach programs, and our Technologists’ Forum special and roundtable sessions. Cover, top; footer of page 3: Rat endothelial cells by Damon Strom, WITec GmbH, Ulm, Germany As always, M&M 2021 will be the premier meeting to attend to stay abreast Cover, bottom left: of the latest technologies, hear about new developments in applications Aloe vera leaf copy by Jose Martinez-Lopez, across all areas of microscopy and microanalysis, and most importantly Química Tech Microscopy and Microanalysis, Juarez, Mexico network with colleagues. Cover, bottom right: Peter A. Crozier, Arizona State University Native vanadium dendrites by Sarah Gain, Centre for Microscopy, Characterisation and Analysis, President, Microscopy Society of America University of Western Australia, Perth, Australia Heather Lowers, United States Geological Survey Footer on page 2: President, Microanalysis Society Detail from Ciliate expels its organelles byJulia Van Etten, Rutgers University, New Brunswick, NJ 2 www.microscopy.org/MandM/2021
PLENARY SPEAKERS For more information on each of the M&M 2021 Plenary Speakers, visit the website at www.microscopy.org/2021/plenaryspeakers Physical Science Plenary Speakers Biological Science Plenary Speakers Maximilian Haider Harald Rose Ondrej Krivanek Knut Urban Kizzmekia S. Corbett Jason McLellan CEOS Gmbh Ulm Universität Nion Co Forschungszentrum National Institutes of Health, University of Texas at Austin, Jülich Vaccine Research Center College of Natural Sciences KAVLI AWARDEES COVID-19 VACCINE DEVELOPERS ANALYTICAL SCIENCES SYMPOSIA A01 Diffraction Imaging Across • Enhancing analytical SEM with FIB, A04 New Frontiers in In-Situ Electron Disciplines including 3D EDS/EBSD and other Microscopy in Liquids and Gases correlative analytics including WDS, CL, (L&G EM FIG Sponsored) ORGANIZERS: Andrew Minor, Professor of Materials Science Raman spectroscopy, EBIC, TKD, u-CT, ORGANIZERS: and Engineering, Facility Director of the National SIMS, and atom probe • Advances in cryo-FIB and working with Huolin Xin, University of California, Irvine Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory beam-sensitive materials Wei-Chang D. Yang, NIST • Innovative micro and nano-structure Stephen House, University of Pittsburgh Jose Rodriguez, Department of Chemistry & Biochemistry, University of California, prototyping • Solid/gas and solid/liquid interaction, Los Angeles electrochemistry and biological and soft matters • 4D-STEM techniques A03 Microscopy and in liquids • Micro/Nano diffraction for biology and • Multidimensional and multidimenional in situ Microanalysis for Real electron microscopy soft materials • Analysis methods for diffraction patterns World Problem Solving • In situ electron microscopy driven by artificial and image reconstruction ORGANIZERS: intelligence • In situ diffraction imaging Ke-Bin Low, BASF Corporation • Big data analysis using deep learning and neural • Cryo diffraction imaging Xiaofeng Zhang, Nanosys Inc. networks • Cryo electron microscopy Jeremy Beebe, Dow Abigail Lindstrom, NIST A05 Advances in Analytical STEM-in-SEM A02 Advances in Focused Ion Beam • Real world problem solving using all ORGANIZERS: Instrumentation, Applications forms of microscopy and microanalysis Jason Holm, National Institute of Standards and Technology and Techniques in and Materials • Practical applications of correlative methods employing microscopy and Dagmar Gerthsen, Karlsruhe Institute of Technology and Life Sciences related techniques Hendrix Demers, Hydro-Québec, Center of Excellence ORGANIZERS: in Transportation Electrification and Energy Storage, • Quantitative approaches for increased Suzy Vitale, Carnegie Institution for Science Dmers confidence in results from non-ideal Annalena Wolff, Queensland University of samples • Transmission imaging in the SEM (BF, DF, mixed Technology • Creative methodologies for preparation imaging modes, Z-contrast, diffraction contrast, Joshua Sugar, Sandia National Laboratories phase contrast, defect analysis) and analysis of real world samples • Latest developments in novel ion sources • Equipment testing, calibration and • Transmission electron diffraction and and FIB instrumentation quality assurance channeling in the SEM (t-EBSD/TKD) • Advances in helium ion microscopy • Transmission spectroscopy in the SEM including scripting, SIMS, nanofabrication, (EDS, EELS) lithography and floodgun imaging • Combined FIB-SEM transmission methods for • Novel geometries, milling strategies sample prep and analysis and non-standard lift outs for TEM/ • Instrumental developments and new detectors STEM and APT • 4D STEM-in-SEM applications (data acquisition, analysis, instrumentation, and control schemes) Microscopy & Microanalysis 2021 Meeting | August 1-5 | Pittsburgh, PA 3
ANALYTICAL SCIENCES SYMPOSIA continued A06 Full System and Workflow A09 Moon Dust, Minerals and A11 Portable- and Laboratory- Automation for Enabling Big Microscopy based Approaches to Analysis Data and Machine Learning in ORGANIZERS: in Cultural Heritage Electron Microscopy Kate Burgess, U.S. Naval Research Laboratory ORGANIZERS: ORGANIZERS: Michelle Thompson, Purdue University Thomas Lam, Smithsonian Institution, Museum Andrew Barnum, Thermo Fisher Scientific Jessica Barnes, University of Arizona Conservation Institute, Suitland, MD Joerg Jinschek, Ohio State University • Investigations of natural, experimental, Barbara Berrie, National Gallery of Art, Wouter Van den Broek, Humboldt University and analog materials to further Washington, DC of Berlin understanding of terrestrial and planetary • Portable- or laboratory-based XRF, FTIR, environments NIR or Raman • Big data in electron microscopy enabled • Advances in sample preparation and • Correlative laboratory-based optical, through full system automation analysis relevant to lunar, planetary, and electron microscopy, or atomic force • Methodologies and software created by the community to combine machine terrestrial materials microscopy • Use of microscopy to explore the origins • Other relevant or emerging approaches learning with microscope operation • and evolution of Earth and planetary of portable or laboratory-based Data augmentation strategies to increase materials approaches will be considered data diversity and close the simulation- • Lunar samples, meteorites and experiment gap micrometeorites, terrestrial samples, • Workflows and data tracking from sample interplanetary dust particles, minerals, preparation through to imaging and planetary building blocks, returned A12 Microscopy and Microanalysis analysis of Biomineralized and samples • TEM, SIMS, FIB, SEM, Microprobe, STXM, Biomimetic Materials and A07 Vendor Symposium atom probe, uXCT Structures ORGANIZERS: ORGANIZERS: Jay Potts, University of South Carolina A10 Unresolved Challenges Kenneth Livi, Johns Hopkins University Lena Kourkoutis, Cornell University in Quantitative X-Ray Sue Okerstrom, Lichen Labs LLC • New methods and techniques; new Microanalysis • Advances in microscopy of combined developments and technologies hard and soft materials ORGANIZERS: • Breakthroughs and new instrumentation • Natural, biomimetic, experimental, and • Improvements to existing instrumentation Aaron Torpy, CSIRO Mineral Resources, engineered materials Clayton, Australia • New analysis programs and data • Correlative microscopy and microanalysis processing packages Nick Wilson, CSIRO Mineral Resources, techniques Clayton, Australia • Approaches, applications and discoveries Hendrix Demers, Hydro-Québec’s Center of • Biominerals as archives of Earth A08 Data Management, Version Excellence in Transportation Electrification and environmental history Energy Storage, Varennes, Canada Control, and Multiformat Aurélien Moy, Department of Geoscience, Analysis in Electron Microscopy University of Wisconsin-Madison, Madison, ORGANIZERS: WI, USA Josh Sugar, Sandia National Laboratories • Quantification using low-energy x-rays Suzy Vitale, Carnegie Institution for Science (e.g. Li K, Fe L, REE M lines) Joe McKeown, Lawrence Livermore National • Valence / chemical state determination Laboratory by x-ray spectroscopy • Advances in backed-up permanent • Improvements to quantification archival systems for storage of large data algorithms, procedures, and standard sets and methods for transfer to these reference materials systems • Quantification of micro/nano-scale • Methods for file version control that allow particles and structures multiple users to share and analyze the • Quantification of beam sensitive materials same data set, with the ability to return to • Improvements to detector/instrument the original when needed technology • Methods for analyzing data between Native vanadium dendrites by Sarah Gain, Centre multiple proprietary formats across Diatom triangle by Larry Gouliard, Jr., for Microscopy, Characterisation and Analysis, different microscopy/software platforms, Independent Microscopist, Pekin, IL University of Western Australia, Perth, Australia including file format converters • Information architecture for local and server-based data analysis software and data storage • Novel methods for analyzing and visualizing large correlated datasets (e.g., 3D serial section, tomography, and 3D plus analytical EDS, EBSD, SIMS, CL, etc.) • Methods for determining the scientifically interesting data when overwhelmed with information (e.g., finding the needle in the haystack) 4 www.microscopy.org/MandM/2021
BIOLOGICAL SCIENCES SYMPOSIA B01 3D Structures: From • Historical perspectives and current • Instrument hardware development Macromolecular Assemblies to developments in the field of high- • Cryogenic sample handling / transfer resolution cryo-EM • Artificial Intelligence based Image Whole Cells (3DEM FIG) • Hybrid structural approaches to study Analysis, Big Data Management ORGANIZERS: macromolecular complexes Melanie Ohi, University of Michigan Life • Assembly and architecture of plant, Sciences Institute B07 Challenges and Advances in animal, and bacterial viruses Teresa Ruiz, University of Vermont • In-situ structural investigations of viral Electron Microscopy Research Cheri Hampton, UES, Inc. · AFRL/RXAS infection and assembly and Diagnosis of Diseases in Wright-Patterson Air Force Base • Structural biology of proteins involved in Humans, Plants and Animals William Rice, NYU Langone Health metabolism, immunity and pathogenesis (FIG associated) • Structure and function of macromolecular ORGANIZERS: complexes in vitro and in vivo B05 Imaging, Microscopy, Claudia Lopez, Oregon Health & Science • Single particle cryo-electron microscopy University • Cryo-electron tomography and Micro/Nano-Analysis Marcela Redigolo, West Virginia University of Pharmaceutical, Ru-Ching Hsia, University of Maryland Biopharmaceutical, and Han Chen, Penn State B02 Visualizing Cells with Cryo-ET Medical Health Products– • Enhancement of sample preparation ORGANIZERS: Grant Jensen, Caltech Research, Development, workflow for EM analysis of complex Analysis, Regulation, and tissue for diagnosis or research Yi-Wei Chang, University of Pennsylvania • Application of advanced or innovative Danielle Grotjahn, Scripps Research Institute Commercialization EM techniques to study host-pathogen (FIG associated) Matt Swulius, Penn State College of Medicine interactions, virulence factors and ORGANIZERS: ultrastructural changes • Cryo-ET allows large macromolecular Daniel Skomski, Merck & Co. Inc. • Ultrastructural characterization of assemblies to be visualized within cells in a near-native state Annie Muske-Dukes, Thermo Fisher Scientific diseases including the use of organoids, • The range of targets that can be • Novel microscopic or spectroscopic xenografts and animal models analyzed by cryo-ET is rapidly expanding methods applied to pharmaceutical, • Novel approaches and applications for to both larger and smaller biopharmaceutical, medical, and health correlative or hybrid microscopy • Sub-tomogram averaging methods can fields (API, excipient, drug, device, etc.) result in high-resolution structures • Root cause analysis of issues related • Many technical advances in to the manufacturing of drugs, medical B08 Cryo-EM in Drug Discovery instrumentation, methods, and software products, and devices in both R&D and ORGANIZERS: are dramatically expanding both the good manufacturing practice (GMP) Leah Frye, Schrodinger power and applicability of the method settings Giovanna Scapin, NanoImaging Services • Utilization of techniques and methods to Anke Mulder, Thermo Fisher Scientific overcome unique product performance • Cryo-EM in structure-based drug B03 From Images to Insights: and pharmacology challenges discovery Working with Large Multi- (polymorphs, contaminants, particles, • Cryo-EM in optimization of potency and Modal Data in Cell Biological etc.) selectivity • Regulatory and data integrity compliance • Use of cryo-EM to address classical Imaging of instrumentation and methods in the ADMET issues such as hERG inhibition ORGANIZERS: pharmaceutical industry • Rapid and efficient determination of cryo- Kedar Narayan, NIH/NCI & FNL • Investigations and evaluations of testing EM structures for drug discovery Cam Robinson, St. Jude Children’s and drug and vaccine development Research Hospital throughout a product lifecycle Jonathan Lefman, nvidia (identification, development, testing, B09 To Fix or Not to Fix? A Question • Correlating images and appropriate supply chain, regulatory, etc.) for Biological Samples metadata from LM, EM, other modalities • Device and throughput challenges (failure ORGANIZERS: (XRM, chemical imaging...) mode analysis, biocompatibility, sterility, Alice Dohnalkova, Pacific Northwest National • Efficiently segmenting and visualizing etc.) Laboratory features of interest Gail Celio, University of Minnesota • Adapting and applying open-source tools and frameworks for image processing B06 Multi-Modal Multi- • Legitimate advantages and deficiencies, and analysis Dimensional Microscopy and how to control them • Implementing scaleable solutions for ORGANIZERS: • Recognizing artifacts in chemically and small and mid-sized labs and facilities cryo- processed material James Fitzpatrick, Washington University School of Medicine • Preparing problematic samples, e.g., volume limitations, high material Xiao-Ying Yu, Pacific Northwest National B04 Michael Rossmann Laboratory density, etc. Memorial Symposium • Immunolabelling in cryo- and Si Chen, Argonne National Laboratory chemical fixation ORGANIZERS: Ben Giepmans, University Medical Center • Handling damage from the electron beam S. Saif Hasan, Department of Biochemistry Groningen, Groningen, NL • Development and applications of post- and Molecular Biology, University of Maryland • Multi-Modal Microscopy, Volume EM, fixation preparation School of Medicine, Baltimore MD CLEM Terje Dokland, Department of Microbiology, • X-Ray Imaging & Analysis University of Alabama at Birmingham, • Analytical Spectroscopy / SIMS Birmingham AL Microscopy & Microanalysis 2021 Meeting | August 1-5 | Pittsburgh, PA 5
BIOLOGICAL SCIENCES SYMPOSIA continued B10 Cryo-EM at Local, Regional, and • Hardware and software upgrades to ORGANIZERS: National Cryo-EM Centers optimize data collection Michelle Digman, University of California Irvine • On the fly data processing. When to Matthew Lew, Washington University in ORGANIZERS: stop data collection? St. Louis Claudia Lopez, Oregon Health & Science • Best practices in a cryoEM facility Kevin Welsher, Duke University University and Pacific North West CryoEM • How to best store, analyze, and Center (PNCC) Andreas Gahlmann, University of Virginia share your data Elizabeth Wright, University of Wiscsonsin- • Data processing: what are we missing? • Fluorescence lifetime imaging microscopy Madison and Midwest Center for CryoET • Super-resolution microscopy (MCCET) • Single molecule spectroscopy Clint Potter, New York Structural Biology B11 Frontiers in Fluorescence • Computational image analysis Center and National Center for CryoEM Lifetime and Super-Resolution Access and Training (NCCAT) Imaging of Biological Structures • Sample preparation: screening optimization and Dynamics PHYSICAL SCIENCES SYMPOSIA P01 Advanced Imaging and • Measurement of light elements in earth P05 Evaluation of Materials for Spectroscopy for Nanoscale and material sciences. Nuclear Applications Materials Characterization ORGANIZERS: ORGANIZERS: P03 Exploring Beam-Sample Mukesh Bachhav, Idaho National Laboratory Lin Zhou, Ames Laboratory Interactions for Uncovering Assel Aitkaliyeva, University of Florida David Cullen, Oak Ridge National Laboratory the Atomic or Dynamic Jing Wang, Pacific Northwest National Ping Lu, Sandia National Laboratories Laboratory Nature of Matter • Advances in imaging and spectroscopy • Current and advanced nuclear fuels and ORGANIZERS: methods for structural and chemical materials Joe Patterson, University of California, Irvine characterization • Irradiation-induced defect analysis: • Correlative approaches combining Stig Helveg, Technical University of Denmark dislocations, loops, RIS, RIP, SFT, etc. spectroscopic and imaging methods (e.g. Jennifer Cookman, University of Limerick • Microscopy and microanalysis advances ABF/HAADF, 4D-STEM, EDS/EELS) to • Development of theories for electron- in nuclear research provide new insight into material structure sample interactions • Data science and data mining of • Real-time and multi-dimensional structural • Precise control over electron probes in microscopy-based datasets and chemical imaging time and space • Standards and interpretation of data for • Defect structural studies in materials • Precise, accurate and reliable high Z materials such as nanoparticles, thin-films, and measurement and reporting of electron multiplayers flux and dose • Optimization of imaging conditions (low • High spatial / temporal resolution imaging P06 Defects in Materials: How We voltage, low dose, cryo etc.) for structure- of beam-sensitive materials See and Understand Them property relationship studies • Using the electron beam to modulate ORGANIZERS: structures and processes Jinwoo Hwang, The Ohio State University • Understanding structure and dynamics Tyler Grassman, The Ohio State University P02 Many Detectors Make from noisy data Honggyu Kim, University of Florida Lights Work: Advances in • Imaging, diffraction, and spectroscopic Microanalysis of Light Elements P04 Emerging Low-Dimensional methods that directly investigate in Synthetic and Natural defects of any nature in both crystalline Nanomaterials and Their Materials and amorphous (disordered) materials Heterostructures • Determining atomic and electronic ORGANIZERS: ORGANIZERS: structure of point defects, extended Anette von der Handt, University of Minnesota Moon Kim, University of Texas at Dallas Jed Mosenfelder, University of Minnesota defects, defect complexes Zonghoon Lee, Ulsan National Institute of • Dynamics of defects – nucleation, Owen Neill, University of Michigan Science and Technology (UNIST) / Institute for interaction, migration, diffusion, Jamie Weaver, National Institute of Standards Basic Science (IBS) annihilation, formation of complexes and Technology • Various allotropes of carbon such as • Defects in next-generation • Advances in technologies for the detection carbyne, nanotube, graphene, and semiconductors and metals, low- of light elements. diamond dimensional materials, energy- • Improvements to existing methods for light • Heterostructure with other emerging generating materials, materials for element analysis. nanomaterials such as TMDs and MXenes quantum information • Soft X-ray spectrometry, neutron • Growth morphology, defects, surfaces • Novel and quantitative digital data activation, EDS, WDS, SIMS, FTIR. and interfaces processing methods for visualizing • Analysis of light elements for energy • Applications in nano-electronics, energy, defects with high sensitivity, accuracy, technology applications. and other emerging devices and precision 6 www.microscopy.org/MandM/2021 for up-to-date meeting information
PHYSICAL SCIENCES SYMPOSIA continued P07 Quantum Materials Probed P10 Investigating Phase P12 Microscopy & Spectroscopy by High Spatial and Energy Transitions in Functional of Energy Conversion and Resolution in Scanning/ Materials and Devices by In Storage Materials Transmission Electron Situ/Operando TEM ORGANIZERS: Lianfeng Zou, Pacific Northwest Microscopy ORGANIZERS: National Laboratory ORGANIZERS: Michele Conroy, University of Limerick Katherine Jungjohann, Sandia Nasim Alem, Penn State University Trevor Almeida, University of Glasgow National Laboratories Mary Scott, University of California Berkeley Leopoldo Molina-Luna, TU Darmstadt Pengfei Yan, Beijing University of • High resolution S/TEM imaging of Judy Cha, Yale Technology, China nanostructures and quantum materials • Phase transitions in functional materials Michael Zachman, Oak Ridge National • Electronic and chemical structure of and devices Laboratory nanostructures and quantum materials • In-situ TEM capabilities (heating, biasing, • Characterization of materials related to • Understanding of the phonon and plasmon cooling, magnetic fields) energy generation, capture, conversion, or resonances and their coupling behavior, • Combination with advanced TEM storage across multiple length scales. particularly at defects, interfaces, and techniques (Phase related, spectroscopy, • In situ/operando techniques for studying the surfaces in nanostructures 4D STEM) dynamic structural and chemical evolution • Studies of topological, skyrmionic, • Controlled electron-beam-induced of energy-related materials under synthesis, superconducting and other quantum transitions working, or processing conditions. materials • Developments and applications of emerging techniques such as 4D-STEM and P11 Fast and Ultrafast Dynamics monochromated EELS for characterization of P08 Advanced Characterization Using Electron Microscopy energy-related materials of Components Fabricated by • Low-dose, low-voltage, and cryogenic ORGANIZERS: Additive Manufacturing Ilke Arslan, Argonne National Laboratory, techniques that provide new insights into ORGANIZERS: Center for Nanoscale Materials the structure, chemistry, structural-property Isabella van Rooyen, Idaho National laboratory David Flannigan, University of Minnesota, Dept. relationships of energy-related materials Subhashish Meher, Idaho National Laboratory of Chemical Engineering and Materials Science • New computational tools for imaging, Federico Sciammarella, MXD USA Pietro Musumeci, University of California, Los diffraction, spectroscopy, or tomography Angeles, Physics Dept. datasets collection and analysis • TEM and STEM studies (imaging, EDS, electron diffraction, EELS) and atom probe • Techniques and instrumentation for tomography (APT) to understand phase high frame-rate S/TEM and SEM P13 Advanced Application of Atom transformations, and microstructural • Method and instrument development for Probe Tomography: Specimen evolution in components produced by improved combined temporal, spatial, various AM processes and energy resolutions preparation, Instrumentation, • 3D microstructure analysis methods on • Methods for reaching sub-femtosecond and Data analysis the micro-, nano-, and atomic scale to stroboscopic and sub-nanosecond ORGANIZERS: understand the integrity of AM fabricated single-shot resolutions Daniel Perea, Pacific Northwestern National Labs, products • Advances and new developments in high- Richland, Washington, USA • Microstructural response of AM components precision generation of discrete electron James Douglas, Dept of Materials, University of to post-processing conditions packets in S/TEM and SEM Oxford, Oxford, UK • Microstructure and defect analysis by both • Discoveries, new insights, and Daniel Haley, Dept of Materials, University of characterization and modeling for insights paradigm-changing observations Oxford, Oxford, UK into solidification and melt pool dynamics in resulting from UEM in physical, • Advances in data processing for improved AM processes chemical, and materials systems accuracy and signal detection in APT, • Current challenges in analytical tools including noise processing, chemical for microscopy and microanalysis of quantification and error processing AM products • New methods for improving reproducibility • In-situ characterization experiments on and reliability of APT data reconstruction AM products and spatial analysis, including advanced Gold nanocubes by data modeling, improved cluster analysis Vasile-Dan Hondoroaba, P09 - Nanoscale X-Ray and Electron Federal Institute for and machine learning approaches. Microscopy Techniques and Materials Research and • Atom probe analysis and sample Testing, Berlin, Germany preparation of materials exposed to Applications in Material Science extreme environments such as temperature, ORGANIZERS: irradiation, corrosion and pressure. Xianghui Xiao, Brookhaven National Laboratory • Multi-length scale and complementary Hanfei Yan, Brookhaven National Laboratory techniques for optimized APT analysis of Huolin Xin, University of California, Irvine complex material systems. • Correlative high-resolution electron and • Advanced specimen preparation, x-ray microscopy applications in material Aloe vera leaf instrumentation, and experimental protocols science by Jose Martinez-Lopez, that enable atom probe analysis of • Correlative microscopy and bulk technique Química Tech Microscopy environmentally sensitive materials for direct applications in material science and Microanalysis, observation of hydrogen, hydrated phases, • Advanced data analysis and modeling for Juarez, Mexico biological and other soft materials, and multimodal and multiscale experiments liquid/solid in • Challenges in correlative microscopy applications Microscopy & Microanalysis 2021 Meeting | August 1-5 | Pittsburgh, PA 7
AWARDS How to Apply For an M&M Meeting Award: Onsite Awards 1. As part of the on-line paper submission process, an applicant The M&M meeting’s co-sponsoring societies confer must flag their paper for award consideration. Only one paper competitively judged awards at the meeting. may be designated per applicant. MSA Student Poster Awards 2. The applicant must appear as first author and presenter of the We believe poster presentations are paper submitted for award. an excellent format for all participants to engage in intensive discussion 3. The applicant must provide the name, title, institution, and with other researchers in the field. To especially encourage e-mail address of their supervisor, who will be contacted to students to take advantage of this opportunity and submit provide a supporting letter and confirmation of applicability papers for poster presentation, MSA provides cash awards to for the indicated award category (e.g. student, post-doc, or the most outstanding student posters (first author) each day technical staff). (up to one in each of three categories). GENERAL CONSIDERATIONS: Ultramicrotomy Award by Diatome Award applicants will automatically be considered for memorial All posters illustrating the use of diamond knife scholarships, conferred by MSA based on the generous support of ultramicrocrotomy are eligible. Prizes include a trip society sponsors. to Switzerland with a visit to the Diatome factory, and Swiss watches. Applicants who have previously received an M&M Meeting Award will not be considered for a second award in the same category. MAS Best Paper Awards MAS annually confers awards for papers STUDENTS: presented at the M&M meeting deemed to All full-time students enrolled at accredited academic institutions be best in four categories. Each comes with a cash award are eligible. High school, undergraduate, and graduate students are generously provided by MAS Sustaining Members. encouraged to apply. Applicants are not required to be members of the sponsoring society. Microscopy Today POSTDOCTORAL RESEARCHERS: Micrograph Awards All full-time postdoctoral researchers are eligible. Applicants are not This competition rewards the innovative blending of art and required to be members of the sponsoring society. science. Winning micrographs will be selected on the basis of artistic merit and general audience appeal. See M&M 2021 PROFESSIONAL TECHNICAL STAFF MEMBERS: website for complete information. Full-time technologists are eligible. In addition, the applicant must be a member of the sponsoring society, current in their dues for the All images used in this brochure are 2020 Microscopy Today year of the meeting. Micrograph Award Winners. AMOUNT OF AWARD: M&M Meeting Awards and memorial awards consist of full meeting registration and up to $1,000 for travel-related expenses. Original receipts must be provided to receive travel reimbursement. Thin Film Crystals by Karl Gaff, K Gaff Microscopy, Dublin, Ireland All award winners also receive an invitation to the Presidents’ Reception, held on the Tuesday evening of the meeting. NOTIFICATION OF AWARD: All award applicants will be notified of their award status approximately eight weeks following the Call for Papers deadline. Unsuccessful applicants will be permitted to withdraw their papers, should their ability to attend the meeting be contingent on the award, within one week following notification. REQUIREMENTS OF AWARD: All award winners must present their paper in person at the M&M meeting in order to receive their award. Awardees are expected to attend and participate in the entire meeting, which runs from Sunday evening’s opening reception through late Thursday afternoon. Awardees are required to attend the Monday morning plenary session, at which their award will be conferred. 8 www.microscopy.org/MandM/2021
MICROSCOPY OUTREACH SESSIONS X90 Microscopy in the Classroom X91 Microscopy Explorations for Families and ORGANIZERS: Kids of All Ages (formerly “Family Affair”) Jane Howe, University of Toronto, Canada ORGANIZERS: Donovan N. Leonard, Oak Ridge National Laboratory Elaine Humphrey, University of Victoria, Canada Josh Silverstein, Pacific Northwest National Laboratory Pat Connelly, National Institutes of Health Rengasayee (Sai) Veeraraghavan, The Ohio State University Please check back on the M&M 2021 website At the frontiers of science, the microscope is an interdisciplinary tool (“Scientific Program” – “Outreach”) for updated which allows students to glimpse into the unknown and link structure information about this session. and function. The Education Outreach Committee of MSA seeks to connect individuals and institutions and ensure that the pathways to microscopy careers and education are exciting, engaging and clear. X92 Project MICRO • Best practices for incorporating microscopy into K-12 and post- ORGANIZERS: secondary classrooms and curricula • Local and national initiatives emphasizing STEM education Elaine Humphrey, University of Victoria, Canada and outreach Janet Schwarz, University of Vermont • Methods to expose students to microscopy in a fun, Pat Connelly, National Institutes of Health engaging and impactful manner The Outreach booth is part of the MSA Megabooth and is available every day the exhibit hall is open. Learn how to set up different stations in a classroom and share your fun microscopy outreach classroom experiences! See different microscope systems in action for use in a classroom; peruse a selection of books suitable for elementary school-age children; and put your name into the draw for a daily door prize. Soap Film by Gerd Günther, independent microscopist, Düsseldorf, Germany TECHNOLOGISTS’ FORUM X30 Technologists’ Forum X31 Technologists’ Forum Roundtable: X32 Technologists’ Forum Workshop Roundtable: Histology Technical Careers in Microscopy – Technique Tips: Special Stains Helpline PhD Not Required and Serial Sectioning ORGANIZERS: ORGANIZERS: ORGANIZERS: Page Baluch, Arizona State University Page Baluch, Arizona State University Page Baluch, Arizona State University Ru-Ching Hsia, University of Maryland Richard Martins Ru-Ching Hsia, University of Maryland • Where to find answers to technical • There are many careers in advanced • Training in the use of special stains is questions analytical and scientific fields that do not usually provided on the job but not as • Available networks to find laboratory require a PhD part of a formal training program so many or clinical experts • Learn about careers from professionals that technicians feel unprepared • Where to get advice when shopping entered the microscopy community with • Learn new techniques using serial for laboratory equipment skills and expertise garnered from previous sectioning and array tomography • How to find labs that provide employment, effective networking and • Learn about stains that are common in specialized histological/lab services military service quantification-based research • Commercial technical careers in microscopy • This session will be useful to histologists include instrument technicians, service at all levels by providing protocols and engineers, applications, sales, marketing and technical advice regarding techniques in account managers special stains and serial sectioning/array • Gather advice that can help in pursuing a new tomography or different career path Microscopy & Microanalysis 2021 Meeting | August 1-5 | Pittsburgh, PA 9
SHORT COURSES X-10 High-Resolution Structure • Electron detector technology suitable for • Biasing holders 4D-STEM experiments • Magnetic field Determination by Cryo-EM • List of possible 4D-STEM experimental • Light illumination LEAD INSTRUCTORS: configurations and references Tim Grant, Morgridge Institute / University of • Analysis software for characterizing large Wisconsin-Madison numbers of STEM diffraction pattern X-15 Data Analysis in Mike Cianfrocco, University of Michigan images and visualization of the results Materials Science • Cryo-EM specimen preparation • Software and tutorial for simulating LEAD INSTRUCTORS: • Introduction to TEM 4D-STEM datasets Eric Prestat, University of Manchester and • Single-particle data collection SuperSTEM Laboratory, United Kingdom • Single-particle image processing Joshua Taillon, National Institute of Standards • Validation of results X-13 Serial EM for EM Data and Technology Acquisition • Introduction to HyperSpy and related LEAD INSTRUCTORS: X-11 Explaining the New Python libraries for multi-dimensional Cindi Schwartz, Rocky Mountain Laboratories/ image and spectra processing and World Order of Biological NIAID/National Institutes of Health analysis Fluorescence Microscopy Guenter Resch, Nexperion, Austria • Curve fitting of multi-dimensional datasets LEAD INSTRUCTORS: • Installation, calibration, and operating • Machine learning Bob Price, University of South Carolina School concept of SerialEM • Big data analysis strategies of Medicine • Image acquisition techniques such as for • EELS and EDS analysis Jay Jerome, Vanderbilt University tilt-series, single-particle, and micro-ED • Optional: application to the analysis • Basics of fluorescence • Ancillary hardware such as direct-electron of atomic resolution images, scanning • Basics of confocal microscopy detectors, energy filters, and phase plates electron diffraction and 4D STEM datasets • New fluorescence imaging modes • Scripting to extend SerialEM • Selection of appropriate imaging modes For this hands-on and interactive short course, attendees will need to install X-14 In situ and Operando software on their own laptop in advance X-12 Guidelines for Performing Approaches to TEM and bring it with them to the short course 4D-STEM Characterization LEAD INSTRUCTORS: (instructions will be provided). from the Atomic to Micrometer Robert Sinclair, Stanford University Scales: Experimental Peter Crozier, Arizona State University Considerations, Data Analysis This course will introduce the fundamental and Simulation concepts for in situ electron microscopy, including: LEAD INSTRUCTORS: • Hot stages David Muller, Cornell University • Gas cells Colin Ophus, Lawrence Berkeley National • Liquid cells Laboratory PHYSICAL SCIENCES TUTORIALS X41 Entrepreneurship in the Microscopy Community X43 X-Ray Imaging & Computed Tomography Several entrepreneurs from the microscopy community will be in attendance for PRESENTERS: Tara Selly, Assistant Professor of Research, Univ. a round table Q&A with tutorial attendees on topics including, but not limited to: of Missouri; Jim Schiffbauer, Associate Professor, Geological Sciences, Univ. of Missouri • Instrumentation development and commercialization • Practical steps to take when starting your own microscopy based business • Introduction to X-Ray microscopy and computed • Panel discussion on business start-up best practices tomography • Role of local affiliated microscopy societies in bringing microscopists and • How spot size, detector pixel size and gemoterical businesses together magnification affect resolution • Reconstruction strategies for isosurface determination • Example applications in the geological sciences X42 Monochromated Aberration Corrected STEM: Why? PRESENTER: Dr. Jordan A. Hachtel, Oak Ridge National Laboratory • Introduction to monochromated EELS • Alignment and tuning in a monochromated Nion UltraSTEM • Different types of monochromated EELS experiments: Aloof EELS, off-axis EELS, momentum-resolved EELS Zosterograptus microtubules by Andrea Brothers, A.B. Brothers • Post-acquistion processing and analysis of ultralowloss EELS data. Microscopy, Manassas, VA Jordan Hachtel is a staff scientist at Oak Ridge National Laboratory. His research focuses on applications of ultralow-loss monochromated EELS to optical, biological, and quantum materials. Beyond this wide class of applications, he has also focused on using novel techniques, unique to ultralow-loss EELS, to access new aspects of the nanoscale infrared response in such systems. 10 www.microscopy.org/MandM/2021
PRE-MEETING CONGRESSES ORGANIZERS: X60 Annual Pre-Meeting Congress for Students, Ru-ching Hsia, University of Maryland-Baltimore Post-Docs, and Early-Career Professionals in Claudia Lopez, Oregon Health and Science University Microscopy and Microanalysis Marcela Redigolo, West Virginia University Organized by the Microscopy Society of America Student Council (StC) Han Chen, Penn State Medical College Saturday, July 31, 2021 • 8:30 AM - 5:00 PM Joe Mowery, Agricultural Research Service, US Department of Agriculture Separate registration required – see registration form (Spring 2021) Mike Reichelt, Genentech INCLUDED IN REGISTRATION FEE: This PMC will include four 90-minute platform sessions with 4-6 speakers each Friday evening social event; breakfast, AM Break, Lunch, PM Break, session, and a poster session. Saturday evening banquet • Automation and streamlining of workflow for diverse EM specimens • Immuno-electron microscopy and correlative LM-EM workflow, advances PROGRAM CHAIR: Piyush Haluai, Arizona State University and challenges BIOLOGICAL SCIENCES CO-CHAIR: Joseph Kim, University of • Challenges and best practices in the preparation of plant, insect, Wisconsin-Madison aquatic/marine, and pharmaceutical specimens for EM PHYSICAL SCIENCES CO-CHAIR: Berit Goodge, Cornell University • Roundtable discussion: instrument-assisted and automated Bio EM SOCIAL CHAIR: Dara Laczniak, Purdue University sample processing, challenges and applications This pre-meeting congress is organized by and for students, postdocs, and early-career professionals, and provides: X62 Recent Developments in Advanced Imaging • A forum for early-career professionals to deliver presentations to and Spectroscopy peers ahead of the meeting Organized by the MSA Aberration-Corrected Electron Microscopy • Opportunities to share research and data in an engaging, non- Focused Interest Group intimidating, and interactive setting • Expanded professional networking, and career development Sunday August 1, 2021 v 8:30 AM – 5:00 PM mentoring from recent graduates Separate registration required – see registration form (Spring 2021) • The opportunity to win awards, determined by peer voting INCLUDED IN REGISTRATION FEE: Breakfast, AM Break, Lunch, PM Break X61 Contemporary Electron Microscopy Advances ORGANIZERS: in Biomedical Research Juan Carlos Idrobo, PhD, CNMS, Oak Ridge National Laboratory Robert Klie, PhD, University of Illinois Organized by the MSA Diagnostic and Biomedical Microscopy Shize Yang, PhD, Arizona State University Focused Interest Group This PMC will focus on developments in instrumentation, techniques, and Sunday August 1, 2021 • 8:30 AM - 5:00 PM analysis for functional aberration-corrected electron microscopy, including: Separate registration required – see registration form (Spring 2021) • 4D-STEM INCLUDED IN REGISTRATION FEE: • Aberration correction Breakfast, AM Break, Lunch, PM Break • Monochromated EELS • Field-free imaging • Low temperature (cryo) characterization BIOLOGICAL SCIENCES TUTORIALS X44 Cryo-EM Structure Determination of Small X45 Traversing Spatial Scales with Correlative Proteins Microscopy PRESENTER: Dr. Deb Kelly, Professor of Biomedical Engineering, PRESENTER: James A.J. Fitzpatrick, Ph.D. Pennsylvania State University Scientific Director, Center for Cellular Imaging • Isolating proteins from COVID-19 patients Professor of Neuroscience and Cell Biology & • Affinity-capture using alternative substrates Physiology, Washington University School • Low-dose Image Acquisition in Milli-seconds (LIAM) of Medicine • Reconstructing small proteins (~50 kDa range) • Introduction to Multi-Modal imaging and concept of Correlative Microscopy • Discussion of current CLEM, CXREM and Cryo-CLEM methods • Practical use of different algorithms for correlating multi-modal data • Examples of Correlative Microscopy in Studies of Disease Pathogenesis James Fitzpatrick is a Professor at Washington University School of Medicine in St. Louis and the inaugural Scientific Director of the Center for Cellular Imaging. His research focuses on the development and application of multi-modal correlated imaging approaches and AI-based image analysis methods to study the pathogenesis of cancer and neurodegenerative disease. Microscopy & Microanalysis 2021 Meeting | August 1-5 | Pittsburgh, PA 11
2021 Thank You to Our Sustaining Members (As of Oct. 2, 2020) Advanced Microscopy Techniques Corp International Centre for Diffraction Data Angstrom Scientific, Inc. IXRF Systems Applied Physics Technologies JEOL USA, Inc. Birla Carbon Lehigh Microscopy School Bruker Nano Analytics Leica Microsystems Carl Zeiss Microscopy, LLC Micron, Inc. CEOS GmbH Microscopy Innovations LLC Dectris Ltd. NanoSpective Diatome US Nion Co. Direct Electron LP Oxford Instruments Duniway Stockroom Corp. PIE Scientific LLC EDAX, Inc. PNDetector GmbH Electron Microscopy Sciences Probe Software, Inc. EXpressLO LLC Quantum Design Inc. Fischione Instruments RaySpec Ltd Focus E-Beam Technology (Beijing) Co., Ltd RMC Boeckeler Gatan SEMTech Solutions, Inc. Hitachi High Technologies America, Inc. Ted Pella Inc. High-Field Consultants TESCAN USA HREM Research Inc. Thermo Fisher Scientific Hummingbird Scientific Tousimis ibss Group, Inc. TSS Microscopy LLC Integrated Dynamics Engineering, Inc. XEI Scientific, Inc. www.microscopy.org/MandM/2021
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