Transplant Hair The complete Guide - Alliance 4 hair

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Transplant Hair The complete Guide - Alliance 4 hair
Hair
Transplant
The complete Guide

                 Methods
                 Cost
                 Clinics
                 Alternatives
Transplant Hair The complete Guide - Alliance 4 hair
Alliance4Hair (alliance4hair.com) is a cooperation of leading forums and patient plat-
forms dedicated to providing independent information for people with hair loss. In addi-
tion to the classical treatment with medication and alternative options, the topic of                             Hair Transplant
hair transplantation is also a major focus, because in many cases a permanent im-
provement of the optical appearance can be achieved.

Other alternatives such as micropigmentation (SMP) will also be presented in order to
                                                                                                                The complete Guide
provide the entire spectrum of possibilities.

This range of options enables the patient to make an optimal decision. Because against                                        Methods - Cost - Clinics - Alternatives
the background of one’s own wishes, the degree of hair loss, the financial possibilities
but also the circumstances of life, there are quite different approaches to a solution
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Alliance4Hair                                                 In cooperation with

                                                                                                                Published by leading European Web Forums in cooperation with
                                                                                                                               acknowledged medical specialists

                                                                                                                        Independent Advice for surgery with no problems

                                                                                                                                      Editor: Dr. Ludger Mentrup

                                                                                                                                  Contact: info@alliance4hair.com

                                                                                                                                         Publisher
                                                                                                                    ASCONEX medizinischer Fachverlag | Andreas Städtgen
                                                                                                                              Kapellenstr. 18, 65606 Villmar,
                                                                                                                             Telefon: +49 (0)6482 94904-55
                                                                                                                                 E-mail: AS@asconex.de

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Transplant Hair The complete Guide - Alliance 4 hair
Authors                                                                                          6          Hair Transplantation on Vertex Area                             68

Introduction                                                                                     8    PRP - Alternative & Complementary Option                              69
Alopecia                                                                                        10    SMP: Alternative Option to Surgery                                    71
     HOW HAIR WORKS AND CAUSES OF HAIRLOSS                                                      11          SMP and Tattoo                                                  71
     Acute alopecia                                                                             13          The possible Tricopigmentation Treatments                       73
     Androgenetic alopecia                                                                      13          Tricopigmentation as part of the Fight against Hair Loss        74
     Alopecia Areata                                                                            14          The Importance of adrressing to specialists of the Field        75
     Cicatricial alopecia                                                                       16          Tricopigmentation and FUE, The Right Strategy                   76
     Medical Treatments for Hair Loss                                                           17                Tricopigmentation Into Scar                               77
           Finasteride                                                                          17                Different Kinds of Scars to cover up                      77
           Dutasteride                                                                          18
           Topical Minoxidil                                                                    18    Concealer                                                             78
           Spironolactone                                                                       18
           Topical Prostaglandin                                                                19    Practical Info - Find a clinic and consultation                       80
           Herbal Treatment                                                                     20
                                                                                                            Searching for a clinic                                          80
Skin Diseases and Hair Loss                                                                    20           Consultation                                                    83
     Seborrhoic Excema                                                                          21          Expectations and Relation to Doctor - Psychology of Hair Loss   84
     Psoriasis                                                                                  22          Side Effects after the Hair Transplant                          86
     Lichen Planus                                                                              23          Aftercare Instructions                                          88
     Lichen Planopilaris                                                                        24          post-operative SKIN-care                                        89
                                                                                                            Swimming in water after hair transplant                         91
Hair Transplant Planning                                                                       25           Waiting for the result                                          92
     Status of Hairloss (Norwood)                                                               26
     The safe and safer donor area                                                              28    Clinic Profiles                                                       95
     Donor reserve                                                                              29
     Coverage Value                                                                             30
     Automated Analysis with Ke-Bot                                                             31
     Hairline Design                                                                            32

FUT (Strip) Method                                                                             34
     Concept of FUE and FUT                                                                     34
     Follicular Unit Transplant -FUT                                                            35
     Opinion: Follicular Unit Transplantation or Follicular Unit Excision: Planning and
     Decision-Making:                                                                           36
     Opinion: Why opt for a Follicular Unit Transplant ?                                        46
            What are the limits of these techniques ?                                           47

FUE Follicular Unit Extraction                                                                 48
     FUE Technology                                                                             49
     Basic FUE Devices - Insertion                                                              53
     FUE “Automatisation “                                                                      55
     FUE Stick & Place Technique                                                                57
     FUE KEEP Placer                                                                            59

Special Hair Surgery Applications                                                              60
     Facial Hair Transplant                                                                     60
     Body Hair Transplant                                                                       62
     Hair Transplant in Women                                                                   65
     EyeLashes                                                                                  66

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Transplant Hair The complete Guide - Alliance 4 hair
AUTHORS

          Raif Umut AYOĞLU,                       Dr. Özlem Bicer                              Marc Costin                          Milena Lardi                       Dr Pauline McCluskey                 Dr. Raphaël Meyer
     Dr. Raif Umut graduated from         Since 2004 she is working on                Product developer & managing          Milena Lardì is the Tricopig-        Dr Pauline is an Irish FUE spe-       LDirecteur Médical à la Clin-
      Ankara University Faculty of      hair treatments and hair trans-                    partner, Hairclinics            mentation Technical Director            cialist, working at The Glas-
                                        plantations with all knowledge                                                    and trainer of the Beauty Med-                                              ique de la Croix d’Or, Genève
    Medicine in 2000. He began his                                                                                                                                 gow Clinic, in Scotland. She       Chirurgien Capillaire – My Hair
                                        and love in order to turn this de-                                                 ical system. This system has          prides herself on natural hair-
    Cardiovascular Surgery training      sire of our patients into reality.              Managing director Sem-           already obtained the approval                                                   Medical (Lyon, France)
    and completed in 2007. In his 10       She is using all the latest in                      traMedo                    of both doctors and surgeons           line design and lifetime donor          Médecin Esthétique et
     years as a Cardiovascular Sur-      technology and without com-                                                       as a complementary or alter-            management. She believes              Lasériste (Lyon, France)
    geon, he was the Chief Surgeon          promising from health and                                                     native technique to surgery or         good quality information is es-       Ancien Chef de Clinique du
     of the Institute for 5 years. He    complying with law and ethics                                                    to pharmacological treatment             sential for patients to make       Centre Hospitalier Saint-Luc
     completed his hair transplant                                                                                          R&D on scalp pigmentation               informed decisions, and is          St-Joseph (Lyon, France)
     surgery training and began to                                                                                        began in 2005 thanks to Italian         happy to provide virtual con-
                                                                                                                            and international partners.                                               Ancien Externe et Interne des
    perform FUE since 2017. He is a                                                                                                                                  sultations via WhatsApp.           Hôpitaux de Lyon (France)
         member of FUE Europe

        Dr. Ekrecm Civas                         Dr. Jean Devroye                              Dr. Bijan Feriduni                Dr. Arslan Musbeh                      Dr. Patrick Mwamba                  Dr. Tayfun Oguzoglu
 Dr. Ekrem Civas graduated in              Since 2000, Dr Devroye has                   Dr. Feriduni is an internation-    Dr. Arslan Musbeh has been           In 2000 he first met Dr. Cole and      Dr. Tayfun Oguzoglu started
Medicine 1993. In 1999, he com-           specialised exclusively in hair                ally recognised physician in      performing hair transplant            started hair transplant. In 2006     hair transplantation 1997 in Is-
pleted residency in dermatol-              restoration. He developed                     the field of hair and eyelash      surgeries for more than 16             Dr. Mwamba opened his own          tanbul, at first FUT. He started
  ogy and opened in 2003 his                                                                                                  years. He uses different             clinic, WHTC, in Brussels. He       FUE in 2003 and motorized
own office in Gaziosmanpasa /                 this passion in the late                 transplantation and cosmetic
 Ankara in hair diseases &hair             1990s, when he decided to                     and reconstructive surgery.       methods such as FUE, DHI             offers methods like Follicular Iso-   FUE in 2007. He is a American
transplantation. He trained in             go to the United States in                     Member of American Hair          and Sapphire FUE. He per-             lation Technique (FIT), Follicular     Board of Hair Restoration
Canada and US, and worked in               order to complete most of                      Loss Association and the         forms only one patient and           Unit Transplantation (FUT), Body       Surgery Diplomate (ABHRS)
 clinics in Poland, Sweden and              his training under Dr John                  Coalition of Independent Hair       maximum two patients as                 Hair Transplantation (BHT),          and was granted Fellow
 Spain. In 2011 he received the                 Cole (Atlanta, USA).                    Restoration Physicians. He is        daily average operations             "Donor Restocking" and tech-        (FISHRS), by ISHRS to a small
 American Board certificate in                                                                                                        number.                   niques for the repair of failed or     number of educator doctors
 hair surgery, and in 2015 was                                                         often being asked to speak at
 accepted to Fellow category                                                           international conferences and                                              unsuccessful hair transplants.
               in US.                                                                             workshops.

        Dr. Koray Erdogan                      Dr. Lars Heitmann                             Andreas Krämer                        Dr. Özgür Öztan,                       Dr. Fares Seffen                    Dr. Nathan Yadun
Dr. Koray Erdogan founded in              Dr. Lars Heitmann is one of                 Since 1998 Andreas Krämer is          Dr. Özgür was graduated from           Doctor Fares Seffen, a hair          Dr. Nathan Yadun is passion-
 2001 his own hair transplant            the few hair surgeons in the                  one of the most important           Ankara University Faculty 2000              transplant specialist in          ate about hair transplanta-
 clinic, and participated in nu-         world who performs all steps                  clinic-independant patient         and founded HLC Clinic Ankara in         Tunisia holds the European           tion and has been practicing
merous conferences. He devel-            personally, without delegat-                  advisors. He regularly visits      2003. He created the fundamen-
oped his own unique FUE sys-                                                                                                                                        Inter-University Diploma in          this discipline since 2003 in
                                         ing any surgical steps to as-                many clinic and if famous for       tal of Beard Hair Transplantation        the Treatment of Baldness                   Rouen (France).
tem known as the “Sequential                                                                                               with the Bifurcated Needle and
     Technique”. In 2016, he             sistants. Exclusively manual                     his participation in TV                                                     (obtained at the Claude
                                          graft removal, formation of                                                     got the patent for it. He is one of
 founded World FUE Institute                                                                                                the few doctors who perform              Bernard Lyon 2 University,
and he was elected president              the recipient openings and                                                                                                                                       He is specialized in hair
                                                                                                                           Stick and the Place technique in         France). Dr. Seffen actively
               2018                         insertion of the grafts.                                                                                                                                    transplant, eyebrows, beard
                                                                                                                          the world. He is the current Presi-      participates several times a
                                                                                                                           dent of FUE Europe Hair Trans-                                                   and unshaven FUE
                                                                                                                                                                     year in the various events
                                                                                                                          plant Society, an ISHRS member                  and workshops.
                                                                                                                            and a Membership Committee
                                                                                                                                       member .

6                                                                   © Alliance4hair - 2021 - All Rights Reserved          © Alliance4hair - 2021 - All Rights Reserved                                                               7
Transplant Hair The complete Guide - Alliance 4 hair
So be careful and don't put everything -              motorised procedure) is selected
                                              and certainly not your few remaining               ◇ high-quality and modern instruments
                                              hairs - on one card. Less is more: Don't              and aids are used (yes, they really
                                              get a lot of hair for little money, but get           cost money!)
Introduction                                  the best possible result with as little hair       ◇ the OP takes place in EU or in a neigh-
                                              as possible.                                          bouring EU - area instead of Turkey of
Hair loss is touching millions - but with                                                           even more far away places
the development of Hair Transplant            Inform yourself! Don't trust every word
Surgery new options are making it possi-      from the internet, EVERY doctor will show          So there are many points to consider, and
ble to reduce impact and make you look        you examples of super patients.                    we like to help you with this extensive
younger in a few hours of surgery.                                                               publication to plan your surgery in the
                                              Clarify your goals:                                best possible way.
But be careful - Hair is not replaceable by
today's standards, so think carefully be-     Nothing against a hairline like at 16 years        So one of our targets is to inform you
fore you make a decision. Think also          - but keep thinking: How do you want to            complete and showing all different op-
about alternatives / additions:               look in 5 / 10 or more years ? Are there re-       tions. So we assembled a highly acknowl-
                                              serves?                                            edged group of specialists, which take
◇ short hairstyle                                                                                over sections of their specific compe-
◇ loose hair                                  What are your wishes?                              tence.
◇ Scalp pigmentation (trico-pigmenta-
   tion)                                      ◇ Hairline
                                                                                                 We like to thank them all for their support
                                              ◇ Density
                                                                                                 !
                                              ◇ Budget
                                              ◇ Language Options                                 The Team of Alliance4Hair

                                              If your money is not enough - wait a little
                                              instead of making a mistake with a "bar-
                                              gain"!

                                              Price differences:

                                              There is a wide price range from 0.50
                                              cents to 5 EUR per graft (and more). Ev-
                                              erybody likes to save, but here "Tata" is
                                              compared to Mercedes.

                                              It always gets more expensive when

                                              ◇ the surgeon works carefully and takes
                                                 his time (which is usually good for the
◇ Sensible medication                            hair follicles and the result) 1,000 folli-
                                                 cles per day or even in 30 minutes, de-
Also be sceptical to heavy advertising.          pending on the technology, are realis-
Man is a biological object, and biology          tic values and are reflected in the
does not give any guarantees. "Guaran-           price
tee" of whatever kind won´t help you if       ◇ the operation is performed by a doctor
there is a problem with your surgery, the        (not an assistant)
hair is simply gone and can´t be replaced!    ◇ the manual FUE (instead of FUT or

8                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved   9
Transplant Hair The complete Guide - Alliance 4 hair
The diagnosis of this loss requires a con-          HOW HAIR WORKS AND CAUSES OF                     any given time. This phase lasts about 3
                                                 sultation and sometimes an examination              HAIRLOSS                                         weeks.
                                                 called "trichogram" (some hairs are taken
                                                 from different areas of the scalp and ob-           Dr. Raphael Meyer                                3) The telogen phase: Rest phase
Alopecia                                         served under a microscope). Baldness is
                                                                                                     WHAT IS A HAIR?                                  The hair is dead and is going to be re-
                                                 defined as baldness when the fall is on
In dermatology, alopecia refers to the ac-       the forehead, above the temples and at                                                               placed by a new hair, which when the
                                                                                                     The hair follicle is an appendix of the skin     time comes will cause its predecessor to
celeration of hair loss. Alopecia is gener-      the top of the skull. Sometimes a hor-              of the skull. It evolves either as down or       fall out. Nearly 10% of the follicles are in
ally referred to as alopecia if this hair loss   mone test is necessary in women. The re-            as hair depending on several parameters          this phase at any given time. This phase
exceeds 100 hairs per day over a longer          sults of these tests indicate one of the            including age and hormonal status. A hair        lasts about 2 to 6 months.
period of time. Baldness (the condition of       following problems.                                 is an organ in its own right with a singular
a bald person) is the ultimate develop-
                                                                                                     and complex organisation. It is to be con-       HOW MANY HAIRS DO YOU HAVE ON
ment of alopecia.
                                                                                                     sidered as a hair with its own specificities.    YOUR HEAD?
USUAL AND ABNORMAL HAIR LOSS                                                                         Hair has an aesthetic role, protecting the
                                                                                                     skull as well as thermoregulation. They          On average, an adult human hair has al-
A person has an average of 100,000 to                                                                are organised in follicular units (FU): a sort   most 120,000 hairs, which are constantly
150,000 hairs and loses about 40 to 100                                                              of common base for random groupings of           being renewed, alternating phases of
hairs per day (permanent loss), with                                                                 1 to 4 hairs.                                    growth, involution, resting and then fall-
peaks of up to 175 during seasonal                                                                                                                    ing out. Depending on each patient, their
changes (seasonal loss in spring and au-                                                             Follicular units are the unit of measure-        age and their ethnic origin, a variable
tumn). It is during this phase that hair is                                                          ment used in hair implantology.                  number of hairs and therefore of UF can
most often renewed. Hair loss is consid-                                                                                                              be observed.
                                                                                                     HOW DOES A HAIR WORK?
ered pathological if a person loses more
than 100 hairs per day over a longer pe-                                                                                                              HOW MUCH HAIR IS NORMALLY LOST
                                                                                                     Hair grows irregularly and unsyn-                EACH DAY?
riod of time, up to two months.                                                                      chronously, in cycles (15 to 20 in a lifetime)
                                                                                                     with phases of varying length.                   Every day, on average, 50 to 100 hairs fall
                                                                                                                                                      out physiologically.
                                                                                                     Three phases follow one after the other:
       The phases of the hair cycle                                                                                                                   WHAT ARE THE CAUSES OF HAIR LOSS?
                                                                                                     1) The anagen phase: growth phase
       The anagen phase is the hair growth phase. This is the longest period of                                                                       Hair loss or alopecia affects both men
       the hair cycle, which lasts 2 to 5 years. The majority of the hair on our heads               Hair grows at an average rate of 1cm per         and women, causing psychological and
       is therefore in the anagen phase.                                                             month. Normally, 85-90% of the follicles         social repercussions that vary from one
                                                                                                     are in this phase at any given time. This        patient to another, but are always nega-
       The catagen phase is a resting                                                                phase lasts from 2 to 6 years. This in-          tive. The main cause is androgenetic
       phase in which the hair no longer                                                             tense production phase requires growth           alopecia. Without being exhaustive, there
       grows. It lasts about 3 weeks,                                                                factors, nutritional intake (iron, proteins,     are many forms of alopecia which can be
       which is significantly less than the                                                          zinc, vitamins) and hormones (oestrogens         grouped into two categories: scarring
       previous phase.                                                                               and thyroid hormones in particular).             and non-scarring.

       The hair does not grow during the                                                             2) The catagen phase: Involution, degra-         1) NON-SCARRING ALOPECIA :
       telogen phase, but remains bound                                                              dation phase
       to the hair follicle. At the end of this phase, the old hair falls out and gives                                                               Androgenetic alopecia :
       way to a new follicle in the anagen phase, the hair cycle begins again.                       The hair stops growing, but remains in
                                                                                                     place. Statistically, 2% of the follicles are    - In men: it is codified in the Norwood/
                                                                                                     in this phase at                                 Hamilton classification

10                                                    © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                                11
Transplant Hair The complete Guide - Alliance 4 hair
- In women: it is codified in the Ludwig         than growing hair. This repeated pulling           ACUTE ALOPECIA                                  ANDROGENETIC ALOPECIA
classification                                   out leads to progressive fibrosis (scar-
                                                 ring).                                             it can be associated with chemotherapy          Androgenetic alopecia is a gradual loss
Telogenous effluvium :                                                                              treatment, stress, severe nutritional defi-     of hair due to the influence of male hor-
                                                 Pseudopelade de Brocq :                            ciencies, iron deficiency, hormonal disor-      mones. It usually occurs between the
It is a temporary hair loss, without minia-                                                         ders, acute radiation; localized alopecia:      ages of 30 and 40, in an average of 70%
turization. Sometimes seasonal (spring,          Hair loss is thought to be linked to an in-        it can be caused by skin problems (tumor,       of men, but in some cases it can occur as
autumn), following childbirth, trauma,           flammatory process of the scalp caused             burning, hair loss), radiotherapy or para-      early as the age of 16. There are many
surgery, diet, high fever, or linked to a thy-   by a disorder of the immune system,                sites (ringworm, lichen); alopecia areata:      causes of hair loss, the traditionally impli-
roid problem or to taking medication or          where the scalp appears whiter and                 Alopecia areata appears to be of au-            cated hormone being dihydrotestos-
an iron deficiency?                              smoother without visible follicles.                toimmune origin (cellular mediation             terone (or DHT). However, the scientific
                                                                                                    mechanism), characterized by a more or          community agrees that it is not the only
A sudden synchronisation of the follicles        All causes of scalp scars: accident,               less large "patch" involvement and at one       one responsible, so epitestosterone could
in the terminal phase (telogen) is then ob-      surgery, burns, radiotherapy, infection            or more sites. This form of hair loss can       play an important role in this process.
served.                                          (lichen planus), inflammation, system dis-         affect the entire head and is known as
                                                 ease (lupus)...                                    total alopecia and sometimes the entire         This hair loss usually begins in the tem-
Alopecia areata :                                                                                                                                   ples and temples (on the front of the
                                                                                                    body: It is Alopecia universalis, and in this
                                                                                                    case there is no hair or hair all over the      head) and in the vertex (the top of the
This is a priori an autoimmune disease,
                                                                                                    body..                                          head). It is characterized by hair thinning
without the mechanism being perfectly
                                                                                                                                                    and loss, which can occur suddenly in
known. It can affect part of the hair, in
                                                                                                                                                    some individuals and more slowly in oth-
the form of bald patches, but can also
                                                                                                                                                    ers. The Hamilton Scale, modified by Nor-
affect the entire hair system (universal
                                                                                                                                                    wood, makes it possible to classify bald-
alopecia). It is a chronic pathology, diffi-
cult to treat with risks of recurrence. For-
tunately, the hair can also grow back on
its own in the long term, and this is the
case for the majority of bald patches.

Trichotillomania :

This is another cause of patchy hair loss,
linked to the compulsive pulling out of
one's own hairs and/or hair. It affects
both adults and children (often transient
in the latter), and may require psychologi-
cal help.

2) SCARRING ALOPECIA :

Alopecia by traction :

Hair loss is the consequence of too much
traction (bun, African braids, hair pulled
back too much). The hair then tends to
break and fall out, resulting in a greater
proportion of hair falling out

12                                                   © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                              13
Transplant Hair The complete Guide - Alliance 4 hair
ness between 1 and 7, where 1 is the ab-        ALOPECIA AREATA                                    The most common form of this condition         regardless of sex or ethnicity, and has an
sence of baldness and 7 is the maximum                                                             usually resolves on its own or with treat-     overall lifetime prevalence of around 1-
alopecia (total hair loss at the gulfs and      Dr. Pauline McCluskey                              ment, with full regrowth taking months or      2%. It more commonly affects younger
vertexes).                                                                                         years. However in rare cases the hair loss     people (most patients get it before the
                                                Alopecia Areata is a type of hair loss that
                                                                                                   may be permanent, or it may develop into       age of 40), and people with a family his-
It should be noted that the references          typically presents as the sudden devel-
                                                                                                   a more advanced form.                          tory or this or other autoimmune condi-
established by the Nordwood scale do            opment of one or more coin-sized
                                                                                                                                                  tions.
not cover all cases. A considerable num-        patches of thinning hair or baldness, usu-
ber of men are affected by alopecia simi-       ally on the scalp or beard.                                                                       Up to half of people with this condition
lar to that traditionally found in female                                                                                                         may also experience pitting and ridging
                                                Alopecia Areata is sometimes referred to
subjects and measured by the Ludwig                                                                                                               of the nails. And the more advanced and
                                                as 'Autoimmune Alopecia' because it is
Scale.                                                                                                                                            persistent the hair loss, the more likely it
                                                thought to be linked to an inflammatory
                                                                                                                                                  is to be associated with psychological
A study from 2011 shows that androge-           process, whereby T cells (a type of lym-
                                                                                                                                                  conditions like anxiety and depression.
netic alopecia is not caused by the de-         phocyte or white blood cell in the body's
crease but by the inactivation of the           immune system) mistakenly attack the                                                              There is no cure for Alopecia Areata, but
stem cells contained in the hair follicle.      body's own hair follicles during anagen                                                           it will usually resolve itself spontaneously
These cells do not turn into "precursor         (growth) phase.                                                                                   within a year or two, or will improve with
                                                                                                   Alopecia Totalis occurs where the dis-
cells" in the hair, so the follicle atrophies                                                      ease progresses to cause total hair loss       treatment. Generally speaking it is less
                                                It is also sometimes called 'spot bald-
and only microscopic hairs are produced.                                                           over the whole scalp. And Alopecia Uni-        likely to regrow quickly if you get it
                                                ness', because of the characteristic small
Thus, a bald man has the same number                                                               versalis is the name given for hair loss       younger, or if it covers a larger area of
                                                round patches of baldness it causes.
of hairs as a man without baldness, but                                                            that affects the whole scalp, face (includ-    scalp.
they are not very visible due to their mi-      The patches may be smooth and com-                 ing eyebrows and eyelashes) and the rest
croscopic size.                                                                                                                                   Topical steroid treatments are available,
                                                pletely bald, or they may contain signa-           of the body (including pubic hair).`
                                                                                                                                                  and in severe cases an oral steroid may
                                                ture 'exclamation mark' hairs. These hairs
                                                                                                                                                  be offered for a short period. Other treat-
                                                typically appear wider and darker at the
                                                                                                                                                  ments that modulate the immune sys-
                                                top (distal shaft), and thinner and lighter
                                                                                                   Another form of the disease is known as        tem may also help to control the
                                                at the bottom where they meet the skin
                                                                                                   Diffuse Alopecia Areata, which presents        progress of the disease. Counselling may
                                                (proximal shaft). They are short (around
                                                                                                   as a sudden thinning of hair across the        be offered to manage the psychosocial
                                                3mm), because they are structurally
                                                                                                   whole scalp, sometimes also rapidly turn-      consequences of Alopecia Areata. And
                                                weak and break easily.
                                                                                                   ing grey. It is important to correctly dis-    camouflage options may also be helpful,
                                                The presence of these hairs, which can             tinguish this from other conditions like       particularly the use of hairpieces or wigs.
                                                be seen either with the naked eye or by            Medication-Induced Hair Loss or Telogen
                                                                                                   Effluvium.                                     Hair transplantation is not usually ad-
                                                trichoscopy, strongly suggests a diagno-
                                                                                                                                                  vised for patients with Alopecia Areata,
                                                sis of Alopecia Areata. In general, a
                                                                                                   The precise cause of Alopecia Areata is        because the underlying autoimmune
                                                greater number of exclamation mark
                                                                                                   not yet fully understood, but it is thought    condition is likely to be ongoing. There-
                                                hairs present means the disease is cur-
                                                                                                   to be a combination of genetic and envi-       fore the transplanted hair may be at-
                                                rently more active, and that particular
                                                                                                   ronmental influences. A number of genes        tacked by the immune system and fall
                                                area of hair loss may increase in size.
                                                                                                   have been identified that are associated       out too, and new patches may also de-
                                                The inflammation caused by Alopecia                with this disease. It can be triggered (or     velop elsewhere in the scalp at any point.
                                                Areata is generally not painful, however           reactivated) by physical or psychological
                                                some patients may feel itching, tingling           stressors, such as a virus, trauma or se-
                                                or burning sensations in affected areas.           vere stress.

                                                                                                   Alopecia Areata affects people equally

14                                                  © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                             15
Transplant Hair The complete Guide - Alliance 4 hair
CICATRICIAL ALOPECIA                           Mix: Acne keloidalis, Acne necrotica                and type determination.                          MEDICAL TREATMENTS
Dr. Ekrem Civas                                What are the causes of cicatricial                  How Is The Treatment In Cicatricial                 FOR HAIR LOSS
                                               alopecia?                                           Alopecia?
Scarred alopecia defines permanent hair                                                                                                           Raif Umut AYOĞLU, MD
loss in which the hair follicles are dam-      The cause of the various cicatricial                The treatment is aimed at stopping the
aged and replaced by scar tissue and           alopecias is not well understood. How-              course of the disease and does not re-         Hair plays an important role in identity,
cause permanent hair loss. The course of       ever, all types of cicatricial alopecias in-        gain the lost hair. The diagnosis should be    self-perception, and psychosocial func-
the disease and hair loss vary. It can         volve inflammation directed at the upper            made early and treatment should be             tioning. Hair loss can be a devastating
progress insidiously over the years with-      part of the hair follicle where the stem            started. As the treatment is delayed, the      experience that decreases self-esteem
out symptoms, or it can watch very             cells and sebaceous gland (oil gland) are           scar area will increase.                       and feelings of personal attractiveness
quickly in months.                             located. If the stem cells and sebaceous                                                           while also leading to depression and anxi-
                                               gland are destroyed, there is no possibil-          Various medical treatments are given in        ety.
Skin findings such as hair loss, skin rash,    ity for regeneration of the hair follicle,          active disease. After the stable period,
dandruff, increased or decreased pig-                                                              scar excision or hair transplantation on       Although hair surgery popularity is rising,
                                               leading to permanent hair loss.
mentation, pustules and draining sinuses                                                           the scar can be planned.                       medical therapy is an important part of
may occur in the affected scalp areas. It      Secondary cicatricial hair loss can occur                                                          hair loss treatment. The overall goal of
is not contagious and can be seen in           for various reasons. Destruction of the                                                            treatment in AGA (Androgenic Alopecia)
both men and women in all age groups. It       hair follicle is incidental to a non-follicle-                                                     is to stop miniaturization and improve
has no inherited feature.                      directed process or external injury, such                                                          hair density. Because of the nature of the
                                               as severe infections, burns, radiation, or                                                         pathology, nearly all medical treatments
What are the types of scarring                 tumors.                                                                                            require lifelong compliance and continu-
alopecia?                                                                                                                                         ity. Conversely, for getting better results,
                                               Who is seen more?                                                                                  medical therapy must be started in early
It is divided into two as hair loss due to                                                                                                        stages of hair loss.
primary and secondary reasons.                 It can be seen in both sexes and all ages.
                                               There is no scientific study on the inci-                                                          Male and female hair loss pathology is
In primary scarring type, hair follicles are   dence. There are scientific studies show-                                                          slightly different. That is why medical
directly affected by the disease and are       ing that it is familial.                                                                           treatment choices can be different in
lost permanently; It provides indirect de-                                                                                                        gender.
struction of hair follicles due to reasons     Are There Diseases Associated With Ci-
such as accident, trauma, radiation and        catricial Alopecia?                                                                                Finasteride
infection in secondary scarring hair loss.
                                               It is usually alone, there is no other con-                                                        Oral
Primary cicatricial alopecia; It is divided    comitant disease, otherwise it is seen in
into three types as lymphocytic, neu-          healthy men and women.                                                                             Oral Finasteride is one of the two drugs
trophilic and mixed.                                                                                                                              which is FDA approved for the treatment
                                               How Is Cicatricial Hair Loss                                                                       of androgenic alopecia (AGA). It inhibits
Lymphocytic: Chronic cutaneous lupus           Diagnosed?                                                                                         5-α Reductase (5AR) type 2 enzyme
erythematosus, lichen pilanopilaris,                                                                                                              which turns testeron to Dihidrotestes-
frontal fibrosing alopecia, graham little      The patient's story is important. How did                                                          teron (DHT). Suggested dose is 1 mg/day.
syndrome, classical pseudopelad, central       it start, was itching and rash accompa-
centrifugal cicatricial alopecia, alopecia     nied, is there a history of trauma or acci-                                                        Finasteride increases hair count, hair
mucinosis, keratosis follicularis spinulosa    dent. It is diagnosed by the dermato-                                                              thickness, and length. Effect on hair
decalvans                                      scopic examination of the patient by the                                                           count is greatest on the vertex scalp,
                                               absence of follicle ostia.                                                                         then frontal scalp, and bitemporal sides.
Neutrophilic: Folliculitis decalvans, dis-
secting cellulite                              Biopsy is required for definitive diagnosis                                                        Finasteride’s side effects include lowered

16                                                  © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                             17
Transplant Hair The complete Guide - Alliance 4 hair
libido, erectile dysfunction, reduced ejac-    In connection with all these effects, the          Spironolactone is growing in popularity                   mended in premenpausal women.
ulatory volume, temporary reduction in         rate of side effects is also high. Dutas-          for treatment of FPHL. Its antiandrogen
sperm count, testicular pain, depression,      teride is often preferred in patients with         effect is used for treatment. Spironolac-
and gynecomastia. Reduced libido as the        insufficient or unsuccessful finasteride           tone used in combination with minoxidil                   Topical Prostaglandin
most frequent side effect, whilst gyneco-      treatment.                                         has been shown to demonstrate greater
mastia and depression were not reported                                                           efficacy when compared to spironolac-                     Prostaglandins (PGs) play an important
at all. Forums, Internet Sites, and Social     Topical Minoxidil                                  tone alone.                                               role in regulation of the hair cycle. La-
media channels exaggerate persistent                                                                                                                        tanoprost is a PGF2a analogue. Cetirizine
sexual side effects associated with finas-
                                               Topical                                            Side effects include headache, de-                        has been found to decrease PGD2 pro-
teride, but controlled clinical trial data                                                        creased libido, menstrual irregularities,                 duction. Information on this medications
                                               Minoxidil is promote hair growth through
have found a low incidence of sexual side                                                         orthostatic hypotension, fatigue, and hy-                 are very limited. Further studies with
                                               vasodilation and stimulation of hair folli-
effects that abate on stopping treat-                                                             perkalemia. Other potential side effects                  longer follow up times are needed to ex-
                                               cles into the growth phase. Topical mi-
ment. These side effects are temporary.                                                           include gynaecomastia and feminization;                   plore the efficacy and safety of this
                                               noxidil has been shown to shorten telo-
Most of them disappered after medica-                                                             therefore, it is not recommended for use                  drugs.
                                               gen, prolong anagen, and increase hair
tion usage has been stopped. Random-                                                              in men. Also oral contraception is recom-
                                               follicle size. Paradoxical hair shedding
ized trials have found finasteride de-                                                                 Medication     Intended      Method of                Dosage           FDA             Adverse Effects
                                               can occur at the beginning of the treat-
creases prostate cancer risk. On the                                                                                   Gender     Administration                             Status
                                               ment due to stimulation of exogen as tel-           Minoxidil              M,F         Topical       %2and %5solution      Approved     Alergy ,Contact
other hand, finasteride decreases                                                                                                                     2 times per day                  Dermatitis ,Hypertri
                                               ogen follicles re-enter anagen. Applied
prostate specific antigen levels which im-                                                                                                                                             cosis, and
                                               twice daily to involved areas of a dry                                                                                                  Cardiovascular
pacts on prostate cancer screening in
                                               scalp. Hair growth is seen within four to                                                                                               Effects
men.                                                                                                                      M,F          Oral         2,5– 5 mg / per day      Not
                                               eight months and stabilizes at 12 to 18                                                                                                     Hipertricosis , Limb
                                                                                                                                                                          Approved         Edema
                                               months; thus a year of treatment is ad-
Topical                                                                                            Finasteride             M            Oral            1 mg per day      Approved      Decreased Libido ,
                                               vised before assessing efficacy. Common                                                                                                  Erectyl dysfunction ,
                                               side effects include: contact irritant der-                                                                                              Ejaculation
Topical finasteride associated with sig-                                                                                                                                                disorder ,
nificant decreases in rate of hair loss, in-   matitis, facial hypertrichosis and cardio-                                                                                               Gynecomastia ,Psyc
creased total and terminal hair counts,        vascular effcts. Propylene glycol is                                                                                                     hologic
                                                                                                                                                                                        impairments, and
and improved hair growth assessments           responsible for this allergic reaction. The                                                                                              PSA level changes
with less systemic side affects. The pre-      5% foam however is free of propylene
                                                                                                   Dutasteride            M,F          Oral             2,5mg /day           Not          Decreased Libido,
liminary results on the use of topical fi-     glycol, which correlates with a lower risk                                                                                 Approved        Erectyl dysfunction,
                                               for skin irritation.                                                                                                                       ejeculation disorder,
nasteride are limited but thus far appear                                                                                                                                                 and Psychologic
safe and hold promise.                                                                                                                                                                    impairments
                                               Oral
                                                                                                   Spiranolakton           F            Oral         25mg/ twice per           Not        Headache,
Dutasteride                                                                                                                                         day and increased       Approved      Decreased Libido,
                                               Oral Minoxidil, an antihypertensive drug,                                                             as tolerated until                   Menstrual
                                                                                                                                                        200mg/day.                        irregularities,
Dutasteride inhibits both Type 1 and Type      was first identified to improve hair loss in
                                                                                                                                                                                          Hyperkalemia,
2 5AR. Dutasteride is three fold more effi-    male androgenic alopecia in 1980. It is                                                                                                    Feminization of men
                                               used for patients who have contact re-                                                                                                     and male fetus.
cacious at inhibiting type 1 5AR and a
                                               actions for topical forms.                          Prostoglandin         M ,F          Oral                                  Not
hundred fold more efficacious at inhibit-                                                                                                                                 Approved
                                                                                                   ( Latanaprost ,
ing type 2 5AR than finasteride. Dutas-                                                            Cetirizine)
teride provides greater suppression of                                                             Herbal                                           Recommmend Oral
                                                                                                    Saw Palmetto                                    dose
DHT than finasteride. However, not FDA         Spironolactone                                       Green Tea
                                                                                                                           M
                                                                                                                          M,F
                                                                                                                                   Oral, Topikal
                                                                                                                                         Oral             320mg/day
approved for AGA.                                                                                   Pumpkin Seed           M             Oral             700mg/day
                                                                                                    Rosemary              M,F      Oral, Topikal          500mg/day
                                                                                                    Grape Seed            M,F            Oral             800mg/day
                                                                                                    Licorice               M       Oral , Topikal         400mg/day
                                                                                                                                                          380mg/day
                                                                                                  M:Male , F:Female

18                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                                                    19
SEBORRHOIC EXCEMA                              ciated with internal organs. A number of
                                                                                                                                                 factors increase risk of developing sebor-
Herbal Treatment                                                                                  Dr. Ekrem Civas                                rheic dermatitis, including:
Saw Palmetto is extracted from palm
tree berries. It effects like Finasteride by
                                                 Skin Diseases and                                Seborrheic Eczema, Seborrheic dermati-
                                                                                                  tis
                                                                                                                                                 Neurologic and psychiatric conditions,
                                                                                                                                                 such as Parkinson's disease and depres-
blocking 5-α Reductase enzyme. The               Hair Loss                                        Seborrheic dermatitis is a common skin
                                                                                                                                                 sion
constents of beta sitosterol and fatty
acids are responsible for its effect. Dose                                                        condition that mainly affects scalp and        A weakened immune system, such as
of 320 mg/day is effective.                                                                       also oily areas of the body. It is a eczema    seen in organ transplant recipients and
                                                                                                  that appears as yellow oily dandruff           people with HIV/AIDS, alcoholic pancre-
Green Tea is a powerful antioxidant. Its                                                          crusts on the scalp, face, eyebrows, the       atitis and some cancers
anti-inflammatory and stress inhibitory                                                           edge of the nose, cheeks, inner and outer
effect which may influence hair growth .                                                          parts of the ears, and pink red rashes.        Seborrheic Eczema is a hereditary dis-
Green tea can stimulates human hair                                                                                                              ease?
growth via its proliferative and antiapop-                                                        Seborreic eczema do not cause any harm
totic effects on dermal papilla cells by in-                                                      to patients other than cosmetic appear-        No it is not.
hibiting 5-α Reductase.                                                                           ance.
                                                                                                                                                 In which seasons is it more common?
Pumpkin Seed oil and its extract have in-                                                         What is the cause of Seborrheic
hibit 5-α Reductase activity with a dose                                                          Eczema?                                        It is more common in winter. The disease
of 400 mg/d for 24 weeks. It’s effective for                                                                                                     is milder in summer.
treatment of AGA.                                                                                 This type of eczema is caused by the ex-
                                                                                                  cessive increase of the fungal microbe         Does the disease increase with food?
Rosemary acts by improving blood circu-                                                           Malaszesia that lives harmlessly on our
lation and improving vascularity helping                                                          skin and the excessive response of the         No food is involved in the development of
the regeneration of follicles similar effect                                                      skin defense system.                           the disease.
that is provided by Minoxidil.
                                                                                                  How common is Seborrheic Eczema?               What are the symptoms of the disease?
Grape seed showed an activity in the
                                                                                                  It is seen around 5% in the society. How-      Although it varies from patient to pa-
proliferation of hair follicle cells and hair-
                                                                                                  ever, patients are often unaware of this       tient, it occurs with thin white-yellowish
cycle-converting activity from the telo-
                                                                                                  situation.                                     scabs on the red pink background, espe-
gen phase to the anagen .
                                                                                                                                                 cially on the nose edge, cheeks, inner and
Licorice has powerful hair growth activity                                                        Is it related to dandruff in hair?             back part of the ear, eyebrows and scalp.
by blocking 5-α Reductase enzym.                                                                                                                 Most patients have no discomfort. Some-
                                                                                                  Dandruff formation on the hair is a mild       times it can occur on the chest and
                                                                                                  form of seborrheic eczema and occurs in        armpits. It may watch with dandruff on
                                                                                                  half of adults.                                the scalp.

                                                                                                  Not everyone with dandruff has sebor-          How is the disease diagnosed?
                                                                                                  rheic dermatitis, but most patients with
                                                                                                  seborrheic dermatitis also have dandruff.      It is easily diagnosed by clinical examina-
                                                                                                                                                 tion. However, in some cases, dermato-
                                                                                                  Is Seborrheic Eczema associated with in-       logical examination and laboratory tests
                                                                                                  ternal organ diseases?                         may be required to distinguish it from
                                                                                                                                                 other diseases (fungal diseases, psoria-
                                                                                                  Seborrheic eczema is not a disease asso-       sis, rosacea, atopic dermatitis).

20                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                            21
Can the disease be cured completely?           PSORIASIS                                          skin diseases should be kept in the inac-      LICHEN PLANUS
                                                                                                  tive phase. Because the results obtained
Symptoms of the disease can be tempo-          Dr. Özlem Bicer                                    with hair transplantation may be less          Dr. Pauline McCluskey
rarily eliminated with the treatments ap-                                                         effective in patients with skin diseases
plied. It is not always possible to be fully   Hair transplantation for patients suffer-                                                         Lichen Planus is a chronic inflammatory
                                                                                                  such as dermatitis,psoriasis. Patients
cured.                                         ing from atopic dermatitis, seborrheic                                                            condition that can affect the skin, nails
                                                                                                  who have this kind of dermatologic prob-
                                               dermatitis and psoriasis                                                                          and mucosal surfaces (such as the inside
                                                                                                  lems should have to know that Hair
Treatment                                                                                                                                        of your mouth). It is relatively common,
                                               Dermatitis and psoriasis are chronic dis-          transplantation is not a contraindication
                                                                                                                                                 affecting up to 1% of the population.
Medicated shampoos, creams and lo-             eases that attack with acute inflamma-             for them if everything is under control.
tions are the main treatments for sebor-       tion. The patient will always experience                                                          The disease is believed to be autoim-
rheic dermatitis.                              this problem on the scalp. This means                                                             mune in nature, meaning that it is caused
                                               that the disease will be active or inactive                                                       when your immune system attacks cer-
                                               in certain periods . The most critical point                                                      tain parts of your skin, mistakenly believ-
                                               is that the treatments applied for the                                                            ing them to be 'foreign'. It is not infec-
                                               disease do not produce permanent solu-                                                            tious.
                                               tions. Moreover, these dermatological
                                               diseases may be the main reason for hair                                                          Symptoms of classical Lichen Planus typ-
                                               loss. In this case, doctors do not recom-                                                         ically include numerous small, flat, shiny,
                                               mend hair transplantation treatment un-                                                           itchy, red-purple bumps on the surface of
                                               less the patient has a case of androge-                                                           the skin, often around 1-3mm in size.
                                               netic alopecia. Even if patients with der-                                                        However as there are a number of sub-
                                               matitis and psoriasis also have androge-                                                          types of the disease, it may present
                                               netic alopecia, there are important crite-                                                        differently, eg:
                                               ria for hair transplantation. The dermato-
                                               logical disease that the patient suffers                                                          ◇ white patches on the inside of your
                                               from should be got inactive. To do this,                                                             cheeks and gums
                                               doctor or dermatologist regulates the oil                                                         ◇ rough and grooved fingernails or toe-
                                               balance of the patient's skin and blood                                                              nails
                                               circulation. If necessary, oral medication                                                        ◇ different shaped lesions such as
                                               and treatment products such as sham-                                                                 straight line or ring-shaped
                                               poo should be used. All these drugs
                                                                                                                                                 While there is no cure, Lichen Planus on
                                               should be prescribed by the doctor of pa-
                                                                                                                                                 the skin tends to go away itself within a
                                               tient before the hair transplant surgery.
                                                                                                                                                 year or two. And there are a number of
                                               After this dermatological treatment, a
                                                                                                                                                 treatments available that can help re-
                                               hair transplant intervention should be
                                                                                                                                                 duce the discomfort from the symptoms
                                               planned to risolve hair loss problem of the
                                                                                                                                                 of the disease.
                                               patient.

                                               Regardless of all these diseases, first of
                                               all the doctor should perform a dermato-
                                               logical analysis in the general hair trans-
                                               plant consultation. In case of dermato-
                                               logical disease diagnosis, the correct
                                               treatment process should be followed.
                                               After hair transplantation, as much as
                                               possible, the patient's dermatitis or other

22                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                           23
LICHEN PLANOPILARIS                             through a prolonged 'passive' phase                                                               lar units”. They vary in size from a single
                                                where the patient does not experience                                                             hair to a four hair follicular units. With an
Dr. Pauline McCluskey                           any symptoms or further hair loss. How-                                                           average of two hairs per follicular unit or
                                                ever it is fairly common for the condition                                                        graft in relation to a hair transplant pro-
Lichen Planopilaris (LPP) is one of the
common forms of scarring alopecia, and
                                                to 'reactivate' some time later.                   Hair Transplant                                cedure. Following the dissection, trim-
happens when the Lichen Planus disease          Once the disease is truly inactive, ideally        Planning                                       ming and cleaning under magnification.
                                                                                                                                                  Technicians start to place the follicular
affects areas of the skin containing hair       after a few years without any symptoms
                                                                                                   It has taken decades for surgical hair         units in the recipient sites.
follicles, such as the scalp.                   after stopping medication, a patient may
                                                                                                   restoration to arrive at the current state-
                                                be considered a possible candidate for
Symptoms of Lichen Planopilaris include                                                            of-the-art techniques. Over the years
                                                surgery.
itchiness, pain, burning or sensitivity.                                                           there has been a number of donor har-
                                                There always remains however a small               vesting and graft placement techniques.
As the disease progresses, it attacks and                                                          All with varying degrees of risk. That in-
                                                risk that the surgery itself may reactivate
destroys the follicles, typically leaving ar-                                                      cluded unsightly scarring to unnatural
                                                the condition, so it is very important that
eas of smooth scalp containing no visible                                                          hair placement and poor yield. Older
                                                patients are monitored and followed-up.
follicle openings. These patches may                                                               methods included punch grafting, flap
gradually expand in size, and several                                                              surgery and scalp reductions. Before fi-
patches may join up to form a larger                                                               nally arriving at Follicular Unit Grafting
area. The hair follicles surrounding these                                                         techniques of donor management and
patches of hair loss may appear red,                                                               graft placement. Follicular Unit Trans-
scaly or spiny.                                                                                    plant (FUT) and Follicular Unit Extraction
                                                                                                   (FUE).
Your doctor may suggest a skin biopsy in
order to confirm a diagnosis of LPP.                                                               Permanent Hair Restoration
As with Lichen Planus elsewhere on the                                                             Surgical hair restoration (hair transplan-
skin, Lichen Planopilaris is a chronic (long-                                                      tation) permanently moves hairs follicles
term) condition, but one which usually                                                             to areas previously affected by hair thin-
'burns out' and becomes inactive over a                                                            ning and loss. Even with advanced
period of some years.                                                                              stages of male pattern baldness. Men re-       One hairs units are used along the hair-
                                                                                                   tain a band of hair around the sides and       line. Along the very front three or four ir-
Available treatments, such as steroids,                                                                                                           regular rows. Two-hair follicles are posi-
                                                                                                   back of their heads. This hair is geneti-
typically aim to calm the immune system,                                                                                                          tioned behind the single hairs. Then fol-
                                                                                                   cally strong. Being immune from the
manage the symptoms of the disease                                                                                                                lowed by the three and four-hair follicles.
                                                                                                   affects of the DHT hormone. That trig-
and preserve the remaining hair. However                                                                                                          Attention is paid to the correct angula-
                                                                                                   gers the male pattern baldness gene.
any hair loss caused by LPP is usually per-                                                                                                       tion and direction. Along with the in-
                                                                                                   Affecting the hair over the top of a man´s
manent, as the follicles have been de-                                                                                                            crease in density. The surgeon can mimic
                                                                                                   head. With a hair transplant. The doctor
stroyed and replaced with scar tissue.                                                                                                            nature, ensuring the outcome is com-
                                                                                                   "harvests" hair follicles from the back and
                                                                                                   sides of the head. When transplanted           pletely natural.
Patients with active LPP are not suitable
candidates for hair transplantation, be-                                                           correctly the hair grow. Permanently in
                                                                                                                                                  Follicular Unit Techniques
cause the transplanted follicles will be                                                           the new area.
attacked by the ongoing disease                                                                                                                   The latest hair transplant techniques
                                                                                                   Follicular Unit Grafting
process.                                                                                                                                          largely differ in respect to donor hair
                                                                                                   Regardless where on the scalp hair grows       management. The extraction techniques
The progression of the disease is some-                                                                                                           to remove the hair follicles from the
                                                                                                   in groups. Hair groups are called “follicu-
what unstable, and it may appear to go

24                                                  © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                              25
donor area. Each technique has pros and        STATUS OF HAIRLOSS (NORWOOD)                       VII: The most severe form of hair loss and     external auditory meatus but has not
cons. Some candidates are more suitable                                                           only a narrow band of hair in a horseshoe      reached the vertex.
for one technique over the other. Some         This picture shows two major patterns of           shape remains on the sides and back of
have the luxury of choosing the tech-          the Dr. O’Tar Norwood's complicated                the scalp. Remaining hair is usually fine      VA: The area of hair loss includes the ver-
nique they prefer. While some benefit          male pattern baldness classification sys-          and not dense.                                 tex. Hair loss more severe than VA cannot
from combining the techniques into one         tem. This system is based on the Hamil-                                                           be distinguished from Types VI or VII.
session. As a result, maximising the num-      ton scale and is often called the Nor-             Variant A:
ber of grafts that can safely be removed       wood-Hamilton scale.
                                                                                                  IIA: The hairline is anterior to the coronal
in one session. Also help repair patients
                                               I: Small to no recession of the hairline.          plane 2 cm anterior to the external audi-
maximise their donor hair characteristics.
                                                                                                  tory meatus.
                                               II: Triangular, often symmetrical, areas of
The donor hair management is the main
                                               recession at the frontotemporal hairline.          IIIA: The hairline has receded back to a
difference in the techniques. The remain-
                                                                                                  point between the limit of IIA and the
ing aspects of the hair transplant proce-      III: Small hair loss enough to be consid-          level of the external auditory meatus.
dure are relatively the same. The grafts       ered as baldness according to Norwood.
are divided, cleaned and checked by the        There are symmetrical deep recession at            IVA: The hairline has receded beyond the
hair technicians. Performed under magni-       the temples that are sparsely covered by
fication. Separated into the natural           hair or bald.
groups of one to four hair follicular units.
The placement of the hairs is the same.        III vertex: The hair loss is mostly from the
The technicians place the hairs units into     top the head (vertex) with limited reces-
the ready made recipient sites created         sion of the frontotemporal hairline that
by the Doctor.                                 does not exceed the recession seen in III.

                                               IV: More severe frontotemporal recession
                                               than in III and there is sparse hair or no
                                               hair on the vertex. The two areas of hair
                                               loss are separated by a band of moder-
                                               ately dense hair that extends across the
                                               top. This band connects with the fully
                                               haired fringe on the sides of the scalp.

                                               V: The vertex hair loss area is separated
                                               from the frontotemporal area but it is
                                               less distinct. The sparse band of hair
                                               across the crown is narrower and the ver-
                                               tex and frontotemporal areas of hair loss
                                               are larger.

                                               VI: The bridge of hair that crosses the
                                               crown is gone and only sparse hair re-
                                               mains. The frontotemporal and vertex ar-
                                               eas are joined together and the extent of
                                               hair loss is greater.

26                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                           27
THE SAFE AND SAFER DONOR AREA                  tensions, braiding …) that destroys the            DONOR RESERVE                                   The donor area starts from the left ear to
                                               donor area                                                                                         the right ear.
Dr. Patrick Mwamba                                                                                Dr. Musbeh Arslan
                                               3. Secondary cicatricial alopecia (from
1. Anatomy criteria based on Norwood           burns) that impaired the classic donor             Whats the donor area
classification of hair loss.                   area                                                                                               How to estimate the grafts
                                                                                                  FUE Hair Transplant is a pattern bald-          number based on the donor
Consider everybody as a Norwood 7 and          4. Rebuild temples points and frontal hair         ness treatment procedure. It consists on        area Capacity
do not harvest beyond it. Anatomy land         line with nape hairs (considered as Body           removing the hair follicles from one part
marks (pretragal line, occipital protuber-     hair transplant)                                   of the body ‘’called donor area’’. Then, re-    The hair transplant surgeon estimates
ance) and measures help to define it.                                                             implant them on the baldness zone               the grafts number according to donor
                                               RULE OF THUMB:                                     called recipient area. The surgeon can’t        area’s capacity.
2. Progression of hair loss overtime                                                              create donor hair. The donor area is ex-
showed that the hairs in the safe donor        -Look at or assess hair caliber                    ceedingly important to achieve the hair         The factors taken in consideration during
area can also thin out and fall. Some pa-                                                         transplantation.                                the evaluation of the donor area:
tients end up with a pattern higher than       -Look at and assess hair pigmentation.
the classic NW7. The elliptical area just                                                         For the FUE hair transplant, the main           ◇ The age of the patient
above the protuberance occipital up to         These signs give you a better under-               donor area is the back side of the head.        ◇ The baldness level
the mastoid region seems to hold very          standing of the probability of the har-            This zone is genetically coded. The donor       ◇ The hair loss statue
good and is the best choice for strip          vested hairs to last longer in the recipient       hair follicle will grow hair on the recipient   ◇ the density of hair follicles per cm
surgery . It is the safer donor area.          area.                                              area. They will never fall.                        square
                                                                                                                                                  ◇ the hair type ( Fine, thick, curly..)
3. Use the dermatoscope to determine           Except from overharvesting, you need to
the safe and safer donor area according        rule out MPB or any other diffuse hair loss                                                        The maximum of follicles extracted per
to the criteria or signs of miniaturization:   pattern to perform surgery while harvest-                                                          session is 3500-4000 from a high dense
thinning or decrease in hair caliber and       ing out of safe donor area.                                                                        donor area.
depigmentation of hairs. If the ration is
                                               CONCLUSION:                                                                                        The Extraction phase
above 15%, the area is considered as NO
SAFE.                                                                                                                                             Process
                                               SURGERY + MEDICAL THERAPY MUST
                                               BE COUPLED TO ASSURE                                                                               The principle of the FUE (Follicular Unit
4. During surgery, you can look at the an-
agen/telogen ratio.                                                                                                                               Extraction) technique is harvesting the
                                               SUSTAINABLE AND LASTING RESULTS.
                                                                                                                                                  hair follicle (graft) one by one with a mi-
5. Conclusion and take-home message:                                                                                                              cro-motor punch. The diameter of the
There is no guarantee for donor perma-                                                                                                            punch diameter depends on the hair
nence; therefore there is no such thing as                                                                                                        type. The size of the punch varies from
“safe donor “ area. We have to anticipate                                                                                                         0,7 mm to 0,9 mm.
and prevent shedding by encouraging
patient to commit to medical therapy to                                                                                                           Each graft removed area never grow hair
slow down the process.                                                                                                                            on the donor area. The hair follicle is re-
                                                                                                                                                  moved from the root and transplanted in
When to harvest out of safe donor                                                                                                                 the recipient area. This makes the extrac-
area                                                                                                                                              tion phase very important.

1. After overharvesting in the regular safe                                                                                                       The grafts extraction phase performed
donor area                                                                                                                                        by unskilled team will damage the donor
                                                                                                                                                  area. When the extraction is not made in
2. In patient with traction alopecia (ex-                                                                                                         homogenous way, the donor area will

28                                                 © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                                  29
have patches and low density. The ex-         COVERAGE VALUE                                     cently developed KE-Bot robotic scan-          AUTOMATED ANALYSIS WITH KE-BOT
traction must be performed by a special-                                                         ning system, the calculation becomes
ist surgeon to avoid any graft damage.        Dr. Koray Erdogan                                  very accurate, allowing the surgeon to re-     Dr. Koray Erdogan
                                                                                                 spect the calculated Coverage Value by
                                              The Coverage Value calculation was de-                                                            The KE-Bot, the newest FUE innovation
                                                                                                 determining the total number of ex-
                                              veloped by Dr. Koray Erdogan as an ob-                                                            by Dr. Koray Erdogan, is an advanced ro-
                                                                                                 tractable grafts from each scalp area
                                              jective method to standardize scientific                                                          botic 360-degree circular scanning sys-
                                                                                                 (occipital, parietal and temporal). This is
                                                                                                                                                tem that evaluates all aspects of hair
                                                                                                 an extremely important concept when
                                                                                                                                                transplantation through high definition
                                                                                                 considering the trends in FUE surgery
                                                                                                                                                photography that provides 3-D scalp
                                                                                                 where multiple surgeries and mega-ses-
                                                                                                                                                modeling and data collection from every
                                                                                                 sions are becoming more common.
                                                                                                                                                angle.

                                                                                                                                                This includes the pre-surgical determina-
                                                                                                                                                tion of each hair’s caliber and density in
                                              criteria for calculating coverage through                                                         the donor area, and overall donor capac-
                                              two components; density and thickness.                                                            ity thereby assisting the surgeon to ob-
                                              This criteria addresses not only overall                                                          tain extremely accurate extraction site
                                              coverage, but also creates a standard for                                                         calculations with potential transection
                                              avoiding donor depletion, an issue that                                                           rates. Additionally, the KE-Bot calculates
                                              has been an area of trepidation to hair                                                           Coverage Value (an important calculation
                                              transplant surgeons for some time and                                                             also developed by Dr. Erdogan) affecting
The donor area reserve                        especially where higher graft counts are                                                          both the donor and recipient areas to in-
                                              concerned. Since the two items of great-                                                          sure adequate homogenization and den-
The hair implant doctor takes absolute        est concern to both the patient and sur-
care to safeguard every hair during the       geon is donor capacity and good cover-
procedure. The donor area differs from        age, this is the main objective of the Cov-
patient to patient. If the hair loss is un-   erage Value Calculation.
stable, the surgeon needs to estimate a
reserve of the donor area for a second        With Coverage Value, the question of hair
Hair Transplant.                              coverage is determined by establishing
                                              area through a geometrical formula; the
                                              multiplication of the number of hairs in a
                                              given area of the scalp by the hair’s
                                              thickness. With the assistance of several
                                              tools, and especially now with the re-

30                                                © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                          31
sity without overharvesting while taking       HAIRLINE DESIGN                                     Treatment : Laser resurfacing , peeling ,…
into consideration normal hair loss with
aging.                                         Dr. Patrick Mwamba

Moreover, KE-Bot is able to determine          1. HAIR LINE IS THE ICE ON THE CAKE
the number of grafts placed in previous        FOR HAIR TRANSPLANT SURGERY
surgeries by counting previous extraction
                                               We have different rules and criteria to
sites. Post-surgically, it scans the recipi-
                                               build the hair line ( finger rules , Da Vinci
ent area and determines the actual num-
                                               rules ,…) . Mastering them will help you to
ber of grafts placed and the density ob-
                                               achieve natural and sustainable results
tained while reporting authentic transec-
                                               overtime .
tion rates in relation to the number of
placed grafts.                                 A. It happens that the hair line looks un-
                                               natural
Although the KE-Bot is presently in lim-
ited production, it promises to be             i. Wrong location ( too low ) while hair loss
adopted by surgeons worldwide due to           continue to progress to an extensive
its extreme accuracy.                          stage

                                               ii. Pluggy look because of bad technique (
                                               misangle grafts , pitting , cobblestone ,..)

                                               iii. Plugs in the hair line

                                               2. FUE CAN CORRECT IT BY ELEVATING
                                               THE HAIR LINE

                                               A) You can use extraction with small
                                               punch and let it heal by secondary inten-
                                               tion .

                                               Possible when the skin is soft , with good
                                               hair angle .

                                               B) Combine extraction with punch and
                                               stiches to decrease the wound size

                                               Big plugs , misangled grafts , scarring tis-
                                               sue

                                               COMPLICATIONS :

                                               - White dots

                                               - Skin depigmentation and discoloration

                                               - Uneven skin surface

32                                                  © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved   33
CONCEPT OF FUE AND FUT                             a different way of removing the hair side      FOLLICULAR UNIT TRANSPLANT -FUT
                                                                        by side. Here, each hair or, more precisely,
                     The principle of hair transplantation is           hair bundle is operated on individually        FUT has been the standard donor har-
                     simple in concept: one takes a hair away           from the scalp with a hollow needle. The       vesting method for many years. Follicular
FUT (Strip) Method   from its previous location, including the
                     tightly fitting growth areas in the skin tis-
                                                                        advantage for the patient is that the          Unit Transplant removes a hair bearing
                                                                                                                       strip from the donor area. The technique
                                                                        long and sometimes unsightly scar can
                     sue, and plants them in a desired loca-            be avoided.                                    is commonly known as "Strip" as it de-
                     tion in the head. What sounds so simple                                                           notes the method of extraction. The strip
                     in principle, however, is considerably more        Even though FUE has become increas-            is taken from an area rich in a high den-
                     difficult in practice. This is mainly due to       ingly popular worldwide, there are still nu-   sity of hair follicles from around the back
                     the fact that hair with its substructures          merous hair surgeons who also use the          and sides of the head. Situated well
                     is very small.                                     strip method to a greater or lesser ex-        within what is considered to be the donor
                                                                        tent.                                          area safe zone. The area affected by the
                     FUT (Strip)                                                                                       male pattern baldness gene. Along the
                                                                        In the following chapter we would like to      occipital bone that slightly protrudes at
                     The first major breakthrough in hair               present the two methods in more detail         the back of the head.
                     transplantation was achieved with the              so that the patient gets an impression
                     so-called FUT or strip method: Here, a             why he or she should choose one of the         The length and width of the strip is de-
                     larger strip of skin and hair is removed           two methods and how this is done.              pendent on certain factors. The number
                     from the donor area, which is then care-                                                          of grafts required to treat the area of
                     fully dissected by assistants under the                                                           hair loss is calculated. The next step is to
                     microscope.                                                                                       measure the donor hair density. This is a
                                                                                                                       calculation of how many follicular units
                                                                                                                       there are per cm 2. At least three mea-
                                                                                                                       surements are taken around the back
                                                                                                                       and sides of the head. Within the area
                                                                                                                       the strip would be removed. The skin lax-
                                                                                                                       ity is measured. Too tight or too loose can
                                                                                                                       affect the closure by suture. This can be
                                                                                                                       tempered by the width of the strip to re-
                                                                                                                       move any undue tension when being
                                                                                                                       closed.

                                                                                                                       Once the strip length and width is calcu-
                                                                                                                       lated the area can be shaved and
                                                                                                                       cleaned. Prepared with a local anaesthe-
                                                                                                                       sia ready for the Doctor to make the inci-
                                                                                                                       sion to remove the strip and then suture
                     The edges of the skin strip are then sewn                                                         the area. The sutures can differ depen-
                     together, leaving only a longer scar on                                                           dent on the Doctor. From self dissolvable
                     the back of the head to be covered by                                                             to permanent to staples. Suturing and
                     the hair that continues to grow there.                                                            closure techniques can allow for hair to
                                                                                                                       grow back through the scar line. This can
                     FUE                                                                                               help to camouflage the area. Even with a
                     Shortly before the turn of the millennium,                                                        short hairstyle a good FUT suture line can
                     various medical practitioners developed                                                           be hard to detect.

34                       © Alliance4hair - 2021 - All Rights Reserved   © Alliance4hair - 2021 - All Rights Reserved                                            35
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