Translating academic careers into industry healthcare professions - Spark-BIH
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careers & recruitment CAREER FEATURE Translating academic careers into industry healthcare professions Though academic institutions have contributed enormously to the remarkable growth in the healthcare industry, a key limiting resource for this continued growth is the creation of career opportunities for doctoral graduates. T he strong biotechnology industry in the United States began with the Box 1 | Exploring career options founding of Genentech in 1976 and the subsequent creation of innovation The evolution of one’s career is often an fields, business, law and technology transfer. hubs in the San Francisco Bay Area and individual experience filled with questions, Starting the dialog was the first important Cambridge, Massachusetts. In Europe, yet, as our survey reveals, many of the step and helped her to take the next one: growth has been slower due to a lack of challenges faced are shared. One common asking some hard questions that required capital to finance promising startups. In theme of many successful careers is that a great deal of self-reflection and personal the most prominent example, Biogen was being proactive helps create options, such assessments of strengths, weaknesses, founded in Switzerland but moved early as asking experts about their journeys passions and interests — something that on to the United States, where funding to find their first jobs. In one case, a an individual development plan11 can help conditions were better. graduate student one and a half years into with. Nearly all of the core challenges Innovation hubs with an abundance of her doctoral program started asking her experienced by her are evident in our capital from venture investors, business friends on the junior professor track and survey of approximately 300 biomedical angels and government incentives other colleagues whether she should stay graduates, who perceived many barriers attract not only the most innovative in academia or go look outside for a job. keeping them from following their ideal healthcare companies, but also talented While all academics said she should stay in career path (Fig. 1b). To break down such individuals contributing brain power to academia, they also highlighted that if she barriers, we would highly recommend innovation creation. The industry needs wanted to leave this was the right time to asking experts for their advice about job two components to survive and grow start preparing. As also seen in our survey opportunities and for introductions. This in the future: capital and talent. While (Fig. 1a), the advice given was heavily can be highly effective and was a key funding and dealmaking continues to oriented toward staying in academia. This element of a recent Career Exploration break records1–3, leading to unprecedented advice led her to search the graduate school Day organized by the CDI group in Berlin new drug approvals by the FDA4 and fast workshop and seminar program, where she (Table 1). At this event, we recommended product development in response to virus saw and applied for a research management follow-up discussions with the experts at outbreaks like Ebola or SARS-CoV-2, talent training for early-career researchers the workshop, which in turn led to specific is a chronically scarce resource5,6. Here, (for reference and similar programs, see introductions to local CEOs in the Berlin we discuss the current state of graduate Table 1). In this week-long workshop, she medtech and biotech community and and postgraduate students in healthcare learned about different avenues to exploit concrete jobs opportunities from employers programs and the ways to translate an biomedical innovations, and also had the eager for these talented individuals. In academic career into a healthcare industry chance to exchange thoughts with many the end, proactive networking is key to profession. We summarize various programs people with backgrounds in different STEM launching one’s career. in the United States and Europe and how governments, universities, pharmaceutical companies and venture capital investors are working toward creating innovation degree and postdoctoral studies at academic understood the value of networking and hotspots to attract and develop the best research institutions. While moving along specific expertise to qualify for their current talent. Finally, we describe possible the academic career path, young scientists job, their understanding of how to translate approaches for shifting one’s career realize rather late that principal investigator a research career to their next job, especially from academia to industry and provide and faculty positions in academia are scarce outside academia, seemed to be less clear. information on various programs and events (less than 18% of PhD graduates will get Almost all students found their current helpful to such a journey. one) and long-term postdoctoral funding position through either a job posting or Companies in the healthcare sector, is limited7. through their network and qualified for including pharma, biotech, medtech and To get an idea of the career awareness employment through specific knowledge e-health companies, require highly trained of biomedical professionals, we conducted and experience. Half of the interviewed and specialized talent and spend significant a poll of over 300 graduate students academic scholars were actively exploring amounts of time and capital on human (master’s degree and PhD) and postdocs at career options, mostly in academia or resources to find and recruit new team various universities in Berlin, Stockholm, industry, and many were uncertain which members. Students in biomedical graduate Silicon Valley and Tel Aviv (see Box 1, career path they should choose. In more programs more often than not pursue an Supplementary Methods and Supplementary than half of the cases, a career development academic research career leading to a PhD Data). We found that while students office helped to some degree in making 758 Nature Biotechnology | VOL 38 | June 2020 | 758–764 | www.nature.com/naturebiotechnology
careers & recruitment a Career advice b Career challenges 0% 20% 40% 60% 80% 0% 5% 10% 15% 20% 25% 30% 35% 40% Academia Unawareness of options / lack of support Industry Focus of studies on one particular career direction (e.g., academia) Medical sector Conflicting interests between me and my None of them supervisor / employer / lack of support Uncertain Personal or family issues Non-profit No action in terms of a career planning on my own behalf Government Transition from education to work in a foreign country Startup Other Uncertain Fig. 1 | Survey results. To gain insight into how biomedical students think about their careers, we conducted a survey of 300 graduate and postgraduate students in the United States and Europe (see Supplementary Methods). a, Students received the most career advice about academic careers. b, A large proportion of students felt a lack of support and awareness of career options blunted their ability to reach their ideal careers. contacts to alumni networks, while specific career development plan11 to encourage for proactive career planning9. Finally, there offers in form of workshops, training, students to think about their talents are books that are great resources to help mentoring or internship facilitation were and core interests, as well as to identify identify one’s strengths while matching them lacking. Importantly, most students were cross-disciplinary mentors both inside and to exciting careers14,15. given advice almost exclusively for academic outside academia. research careers, and half felt they were Similarly, graduate students on the shared Career opportunities in the healthcare unaware of various non-academic career campus of the Charité Medical School and sector options and were lacking work experience Humboldt University in Berlin worked Companies in the healthcare sector range or networking skills to be able to get their together to create the Career Development from large pharmas with tens of thousands dream job. The survey shows that graduates Initiative (CDI)12. The students also of employees to university startups with and postgraduates in the life sciences established their own individual career a handful of team members. Innovations are aware of what is needed to translate development plans and were able to work and ideas out of universities are typically academic careers, but seem to lack with their respective programs to design financed by government grants, business the knowledge of where to find and new coursework and permit new training angels and investors such as venture capital establish the skill sets, mentorship outside of their majors. In addition, they (VC) firms, and the translation from idea and/or networks necessary to facilitate created a lecture series where scientists to company is in many cases facilitated by career choice and translation. working in non-academic positions speak several stakeholders: the founding team, about their journey and how they landed the university technology transfer office, Life science career development their ideal job. The speakers agreed to intellectual property lawyers, entrepreneurs challenges become mentors and advisors in this and VCs themselves. Starting with university career programs, the program, making personal introductions to Recently, the classical VC investment poll highlights students’ needs and desires companies in the larger Berlin community. model has shifted more and more for additional training in areas outside their Outside speakers represent a valuable toward company creation and early-stage core curriculum. While some universities mechanism for scholars to learn about investment in order to bridge the gap are quite progressive and have developed skill sets that will be truly useful in the real between science and capital markets. One innovative solutions (Table 1), there is much world. The CDI group also uses design of the main tasks of VCs is human resource room for improvement8,9. Intriguingly, in thinking approaches13 in workshops to management. Most VCs spend a significant a growing number of examples, changes explore career options and prepare for amount of their time attracting and in how universities support career interviews. Moreover, by networking with retaining the best talent for newly financed development are being driven by students several local not-for-profit organizations, startups. Since investors search actively and postdoctoral fellows themselves. In one including Berlin Partners, the students for new ideas to invest in and talent to such example at Stanford University10, pairs recruit representatives from local biotech recruit, many have started initiatives to of student representatives from each of the and medtech companies to a Young Talent increase talent attraction. The idea behind major life science graduate programs in Career Day12 where, via a matchmaking most programs is to develop the talent developmental biology, neuroscience, cell algorithm, attendees can be paired with pool of tomorrow, allowing the exchange biology and pharmacology, among others, prospective future employees. Many of these of many different ideas, bringing different worked not only to restructure core course features are also seen in programs at top technologies together and thereby requirements, but to increase the fraction innovation-oriented universities in Europe creating an innovation ecosystem. Some of electives that could be taken anywhere and the United States (Table 1). Of note, examples of public and private efforts to across campus, including the schools of efforts at the Scripps Research Institute expand job opportunities that capture education, public policy, engineering and have led a graduate level course, Effective young talent in the biomedical areas business. They also developed an individual Career Planning for PhDs, that advocates are highlighted below. Nature Biotechnology | VOL 38 | June 2020 | 758–764 | www.nature.com/naturebiotechnology 759
careers & recruitment Table 1 | Some institutions with progressive career development programs for doctoral and postgraduate students Institution Country Specific information Website Universities University of California, US Occupational outlook book, salary https://career.berkeley.edu/Sciences/Sciences Berkeley recommendations Boston University US Comprehensive, mature approach http://www.bu.edu/careers/ Harvard University US Approaches from tuition assistance to https://hr.hms.harvard.edu/working-hms/career-development Medical School retirement Karolinska Institute Sweden Focus on inside and outside career https://education.ki.se/career-service Massachusetts Institute US Exploration of chances in industries, https://capd.mit.edu/ of Technology especially biotech Max Delbrück Center for Germany Focus on researchers, also outside https://www.mdc-berlin.de/content/aspire Molecular Medicine academia Scripps Research US Career planning course for PhDs https://education.scripps.edu/graduate/doctoral-program/ Institute Stanford University US Motivation by career story telling http://med.stanford.edu/bioscicareers.html University of Cambridge UK Appealing video tutorials from industries https://www.opda.cam.ac.uk/career-development University of Copenhagen Denmark Curriculum with speakers from outside https://www.synapse-connect.org/ + Technical University of academia Denmark University of Heidelberg Germany Startup management https://www.graduateacademy.uni-heidelberg.de/karriere/ University of US Individual career development plan https://www.umassmed.edu/gsbs/career/ Massachusetts Medical School University of Oslo Norway Focus on networking outside academia https://www.uio.no/english/studies/career/ University of Oxford UK Skill training courses https://www.medsci.ox.ac.uk/study/skillstraining/career-development Tel Aviv University Israel Company presentations https://english.tau.ac.il/career_center Other academic organizations California Life Science US Biotech primer for delivery of industry https://califesciencesinstitute.org/careers/professional-development/ Institute knowledge Einstein Center, Charité Germany Innovative initiative run by medical and https://www.ecn-berlin.de/career/CDI.html Medical University neuroscience students Life Science Career Canada Student initiative to bridge academia and https://lscds.org/ development Society industry STEMPeers World’s biggest STEM community http://www.stempeers.org/ network VC internships and fellowships about new trends in academia, enlarge their then, the region has developed into one Venture capital firms have raised academic networks and, in the best-case of Europe’s most successful biotech hubs, increasingly large funds in recent years, scenario, attract talent for their portfolio birthing multi-billion-dollar companies such allowing internal investment teams to grow. companies. Such programs provide an as Ablynx and Argenx. To ensure excellence Today a number of VC funds are large easy way to learn the business aspect of in science, the VIB pays special attention enough to provide in-house internship startup companies, become familiar with to the professional development of all or fellowship programs on a rolling basis the drug or device development process co-workers. Human resource development (Table 2). Internships usually last between and interact with different stakeholders at the VIB includes training, mentoring, 6 and 12 months and pay a small salary in healthcare. The most valuable lesson coaching and career guidance inside or or are financed by a grant. Programs are from the experience is the understanding outside of academia. To do so in an efficient directed toward graduate students still that investors work together with a wide manner, the VIB established its own career enrolled in their PhD curriculum and range of specialists, giving the intern plenty center aimed at graduate students. At the looking for early professional experience. of opportunities to establish personal VIB and other innovation hubs, graduate Interns usually learn broadly about the relationships and learn as much as they can. students can access a diverse set of resources healthcare ecosystem, learn how VCs to attend workshops, receive training in evaluate prospective investments and, most Creating innovation centers and hubs various skill sets and increase their own importantly, get exposed to many startup The foundation of the VIB in the Flanders awareness of different professional skills. companies. At the same time, VCs are able region of Belgium in 1996 marked the first The VIB created an innovation hub to see different perspectives and ideas, learn innovation hub in Europe (Table 2). Since similar to the Kendall Square ecosystem in 760 Nature Biotechnology | VOL 38 | June 2020 | 758–764 | www.nature.com/naturebiotechnology
careers & recruitment Table 2 | Innovation hubs and internships Innovation hub Country Specific information Website Academia VIB Belgium Successful spinouts, networking, http://www.vib.be career center Babraham Research Campus UK Successful spinouts, networking, http://www.babraham.ac.uk conferences BioMedX Germany Networking http://bio.mx University of Cambridge Enterprise UK Networking, education, mentoring http://www.enterprise.cam.ac.uk program Curie Tech Transfer (insC2) France Networking, initiative for innovation https://techtransfer.institut-curie.org/page/ education inc2-initiative Enterprising Oxford UK Networking, education http://www.eship.ox.ac.uk Innovate Carolina US Networking, workshops, courses on https://innovate.unc.edu/ entrepreneurship Max Planck Innovation Germany Associated innovation programs; http://www.max-planck-innovation.com life science incubators, lead discovery center, conferences Oncode The Netherlands Oncology-focused innovation hub http://www.oncode.nl Independent Ascenion Germany Networking, conferences, http://www.ascenion.de workshops BioInnovation Institute Denmark Networking, events https://bioinnovationinstitute.com/ AdMare Bioinnovations Canada AdMare Academy training http://www.admarebio.com BaseLaunch Switzerland Networking http://www.baselaunch.ch Biocat Catalonia Networking, education, job board http://www.biocat.cat BioM Germany Events, workshops, job board http://www.bio-m.org Euroasanté France Networking events http://www.lille.eurasante.com Industrial Biotechnology Innovation Scotland Networking, job board http://www.ibioic.com Centre MassBio US Success stories, networking, http://www.massbio.org education, mentorship MTPConnect Australia Events, training opportunities http://www.mtpconnect.org.au/overview Oslo Science Park Norway Networking, courses, lectures http://www.forskningsparken.no/ Oslo-Science-Park Pharma companies Bayer Life Hubs Worldwide Networking, lectures http://www.innovate.bayer.com/lifehub-overview Johnson & Johnson Innovation JLABS Worldwide Networking, lectures, workshops https://jlabs.jnjinnovation.com Pfizer Healthcare Hub Worldwide Focus on eHealth https://www.pfizer.com.au/collaboration/ pfizer-healthcare-hub; https://www.pfizer. co.uk/pfizer-healthcare-hub-london; https:// healthcarehub.pfizer.de VC internship and fellowship programs Duration 5am US 6 months https://www.5amventures.com Apollo Health Ventures Germany 12 months https://www.apollo.vc/careers/ moonshot-venture-fellowship-program/ Flagship Pioneering US 3 months https://www.flagshippioneering.com/join/fellows LSP The Netherlands, 6 months https://www.lspvc.com Germany M Ventures The Netherlands 6 months https://www.m-ventures.com/fellowship Nextech Invest Switzerland 6 months https://www.nextechinvest.com/positions/ fellowship-program/ Vida Ventures US 3 months + https://www.bu.edu/best/files/2020/02/ Vida-Ventures-Fellowship-Program-2020.pdf Nature Biotechnology | VOL 38 | June 2020 | 758–764 | www.nature.com/naturebiotechnology 761
careers & recruitment Cambridge, Massachusetts, where scientists, the life science industry, with topics ranging individual talents can inform the selection of entrepreneurs, and investors from academia, from discussions on early science to drug professions. While understanding individual startups, biotech and pharma meet regularly. approval, the regulatory path and scientific strengths and weaknesses is important, Such interactions are the first steps to topics. Attendees obtain insights into diverse interacting with professionals working in understanding the various opportunities topics from Johnson & Johnson employees, jobs of interest is essential to reality-check and possibilities for life science graduates. entrepreneurs or academic scientists. expectations and further map out details of Not every résumé is the same and, more Together, such initiatives are beginning jobs and personal interests. It also helps to often than not, individuals working in the to bridge the gap between large pharmas, follow the journey in a personal notebook, industry have a diverse skill set that they innovative companies and scientists, summarizing and detailing all information acquired working in different jobs. fostering exchange between people from on people, jobs, companies, events and Other innovation hubs have built on the diverse professions. workshops one has attended. This serves as a success of the VIB and combine regional personal reference and makes it easier to go excellence with talent development (Table 2). Empowering exciting careers back and reanalyze decisions and opinions. Stakeholders in such hubs vary from How can we empower the next generation region to region depending on regional of young scientists to get the job of their Conclusions strategy and the most active business dreams? Scientists in academia may be Exploring career options will come with areas. Historically, the Netherlands has highly successful, dedicated and innovative, surprises. With luck, it should not only a strong VC sector; in fact, the first VC but translating skills developed in an expose strengths and weaknesses but investments were made in Holland, academic setting to an applied profession also create enthusiasm and passion for financing expeditions by ship to explore continues to be a challenge. The process of specific topics. One absolutely essential new continents to trade coffee, tea and other one’s own career translation can be seen as ingredient in translating one’s training resources. Relying on a strong financial a road with predefined junctions. Like the in academia to a faculty job or industry sector, a number of biotech companies planning for a road trip, career transitioning is strong communication skills, as well were created in the Netherlands16. However, needs planning and an idea of where the as the courage to approach people across the academic institutions fueling such journey should lead. networks, asking for introductions or even innovation are distributed over the country The golden rule for all important cold calling others, especially those with and not well interconnected. Therefore, decisions is to start planning early. For professional paths that look interesting. the Oncode Institute was created to unite example, when considering a job change or Beyond academic services, we recommend scientists under one organization with the transition from university to industry, the exploring career development programs mission of translating scientific innovation process can usually take a year to a year and and innovation hubs around the world into new therapies. The shared mission a half. Also, some entry-level jobs might that host a range of networking and career forces researchers to think about their own only be available to those with prespecified opportunities. Attending a seminar or research from a different angle and provides degrees and work experience. This means lecture series outside your normal scientific new possibilities for creative scientists to that, in some cases, it will be easier to enter area is a good starting point for networking invent products based on their research a large pharma after a master’s degree rather and communicating with others. For those topics. Top-quality addition of value by than after a postdoctoral fellowship. Thus, with an academic career interests, these translation of research results requires a an ideal time to start your career transition activities should increase your passion for highly specialized talent pool. The close is to begin shortly after the first year into pure science and knowledge for knowledge’s proximity of scientists, entrepreneurs, a master’s or PhD program. At that stage, sake while providing insights into how to investors and tech transfer specialists, with graduate students usually have a first idea build a successful career in academia by the shared goal of translating ongoing of their academic and lab environment and finding mentors. For those still exploring research, forms the foundation for everyone whether they are passionately focused on their future, these experiences should help involved to think beyond their academic an academic path or are already thinking increase one’s awareness of the wide range of career path. outside the academic box. Take advantage of careers in the healthcare industry and lead Importantly, large pharmas are individual career development plans11,12. It to an early preparation toward a professional also interested in fostering innovation is also a good time to tap into local graduate goal. It is critical to take a proactive approach ecosystems, recruiting the best talent and schools, universities and community to career building, adding new skill sets promoting translation of breakthrough programs or activities that encourage and identifying opportunities to broaden science (Table 2). For example, Johnson internships, workshops and other activities experiences. Finally, be curious and ready & Johnson was one of the first pharmas outside of the degree curriculum (Table 1) to challenge your own expectations, as they to create a separate investment arm in order to collect as much information as do not always match reality, and then take a and innovation department to advance possible on a variety of different professions. chance and walk through opportunity’s door healthcare innovation by collaboration with By the second year of graduate education, to the career of your dreams. ❐ academia and startups. It created innovation the collected information can then be used centers for scouting and collaborating and to map the landscape of professions and Sinje Gehr 1, Craig C. Garner 1,2 ✉ JLABS to incubate early ideas and interact associated skills required. This allows one and Karin N. Kleinhans 3 ✉ with the eco-environment. JLABS are to adjust one’s curriculum or add another 1 Charité Medical University Berlin, Berlin, Germany. innovation hotspots in various cities; they degree qualification in an interdisciplinary 2 German Center for Neurodegenerative Diseases engage with the different stakeholders. study program to meet the requirement of a (DZNE), Berlin, Germany. 3LSP, Munich, Germany. The interaction encompasses a variety specific career or profession. To understand ✉e-mail: craig.garner@dzne.de; of communication channels, from social one’s personal skill set better, one can look at kkleinhans@lspvc.com media to personal presence at events. personal preferences and talents cultivated JLABS offer a wide range of courses, inside and outside academia. In the end, Published online: 9 June 2020 workshops and talks on various aspects of the overlap between required skills and https://doi.org/10.1038/s41587-020-0552-x 762 Nature Biotechnology | VOL 38 | June 2020 | 758–764 | www.nature.com/naturebiotechnology
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