THE VALORIZATION OF PUBLIC RESEARCH IS ON THE FAST TRACK - SATT Sud-Est
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2017 ANNUAL REPORT
5 YEAR SPECIAL EDITION 2012-2017
THE VALORIZATION
OF PUBLIC RESEARCH
IS ON THE FAST TRACK
www.sattse.com
Project financed with the support of
the European Union with the European
Regional Development Fund
La science pour la santé
From science to health
MECAPTOR
Sensor for detecting and quantifying humidity
or a solvent in gas form such as ethanol
The operating principle of the sensor is based on the stress relaxation
of a two-layer lamella consisting of a sensitive layer and a flexible substrate
Institut Matériaux Microélectronique Nanosciences de Provence
(IM2NP, UMR 7334 Aix-Marseille Université, Université de Toulon, CNRS)
SATTMAP 2012-2017....................P.4-5 Communications...............................P.22-23
SATT at a glance...............................P.6-7 Maturation Transfer
Spotlight.................................................P.8-11 the Keys of Valorization................P.24-35
Ecosystem.............................................P.12-15 SATT The People..............................P.36-37
The Interview.......................................P.16-17 14 SATT for a more
Innovative France.............................P.38-39
The Directors Report.......................P.18-21
FOREWORD
The first five years of our existence have
taught us a lot about how a complex
innovation ecosystem operates, involving
multiple players, public and private, local
and international, operating on different
scales of time, interest and need.
To overcome this hydra and support researchers in their search
for entrepreneurs, we had to find ways to improve, consolidate
our organizations, professionalize our management, build
a detailed picture of our territories, map our audiences and
enhance the expertise of our teams.
On a national level, the SATT Network can now rely on more
than 600 experts in valorization. In South East France, this
impetus has won several emblematic victories such as the
introduction of digital technologies in the service of culture
and heritage, which were lacking without our intervention, the
establishment of a foreign company on our territory to operate
a patent license owned by a university shareholder, or the
support of a start-up from public research up to its transfer for
several millions last year. These are just some of the examples
that we wanted to highlight in this annual report, which sets out
our activities and the mobilization of our teams over five years,
serving public research institutions and the territories of South
East France. You will have a clear vision of our missions and
our results, whether it is our quantified results, the innovative
discoveries that we have supported or the strategy that we
have implemented with our team, of which I am very proud.
SATT Sud-Est is There is still much to accomplish. First, to make ourselves
at the heart of
as attractive to industrialists as we are to researchers and
their institutions, as evidenced by the personalities in our
the modeling
ecosystem. Then strengthen our territorial impact by more
effectively interconnecting our presence with the players of
of future humanity
innovation. To this end, we have, in particular, supported the
Métropole Nice Côte d’Azur and Université Côte d’Azur, both
nominated as winners of the "Territoire d’Innovation de Grande
Ambition" call for expressions of interest in the framework of
the "Programme d’Investissements d’Avenir" as Mr. Christian
ESTROSI emphasizes in this report. Finally, to strive towards
organizational stability and financial independence by
improving our performance indicators. This is an issue of social
appropriation that affects all aspects of our daily lives - an
issue we intend to meet as a team.
Laurent BALY
President of SATT Sud-Est
President of SATT Network
SATTMAP
2012-2017
AVIGNON
Founding shareholder
11 invention
since 2012
disclosures
including 3 in 2017
1 license granted
since 2012
2 start-ups created
since 2012*
MARSEILLE
Founding shareholder
265 invention disclosures
since 2012 including 43 licenses granted
since 2012 including 10 start-ups created
since 2012*
56 in 2017 10 in 2017
La science pour la santé
From science to health
Non-shareholder Founding shareholder Founding shareholder Founding shareholder
founding partner
7 invention
disclosures 5 invention disclosures
since 2012 including
173 invention disclosures
since 2012 including 3 invention disclosures
since 2012*
since 2012* 2 in 2017 30 in 2017
MINOPAIN project
to assess acute pain 15 licenses granted since
2012 including 5 in 2017
in infants, see section
2 start-ups
Spotlight created
since 2012*
* : indicators by shareholder establishment
Founding shareholder
SATT presence in the territory:
a SATT Sud-Est branch has been
located in Sophia Antipolis since 2012
and includes 4 permanent staff.
66 invention disclosures
since 2012including
3 in 2017
NICE 6 licenses
ince 2012
granted
3 3since
start-ups created
2012*
Non-shareholder
founding partner
18 invention disclosures
since 2012*
SHARK Project, a connector device
inspired by the sharks jaw for fixing
vessels or vascular prostheses while
preserving the vessel walls.
CORTE
TOULON
Founding shareholder
Founding shareholder
SATT presence in the territory:
26 invention disclosures
since 2012
Technology Transfer Manager
based at the University,
including 2 in 2017 in Corte. In six months,
the number of invention
disclosures has doubled.
2 license granted
since 2012*
19 invention
since 2012
disclosures
including 7 in 2017
1 license granted
since 2012*
SATT
AT A GLANCE
* working for the shareholder partners **as at December 31, 2017
SIMPLIFIED
JOINT-STOCK
COMPANY WITH
FOUNDED IN REGISTERED
CAPITAL OF
SHAREHOLDERS
AND FOUNDING
MEMBERS
FINANCING
FINANCING FROM ERDF
OVER 10 YEARS FOR 2013-2017
RESEARCH RESEARCH
TEAMS* LABORATORIES*
RESEARCHERS AND PH.D. STUDENTS*
46
PERMANENT
MEMBERS
34
OF STAFF**
HEAD OFFICE IN
FRENCH RIVIERA BRANCH IN
PROJECT ENGINEERS IN
THE LABORATORIES **
From SATT's creation to December 31, 2017
2017 Annual Report I page 7
5 YEAR SPECIAL EDITION 2012-2017
SATT Sud-Est turnover in 2017 amounted
to 3.4 million euros, partly thanks
to the sale of a start-up.
PROJECT FLOWS,
AMOUNTS INVESTED IN MATURATION,
START-UPS CREATED
114 109 67 30 19 20 19
104
98 59
89 16
50 49 27 25
44 13
78 20
19
18
28 6
Invention Patents and New innovation License agreements
disclosures software protection projects during signed during the year
during the year during the year the year
7,16
214 M€
6
189 188
184
162
4,80
M€ 4
108 3,45
M€ 3
2,94
M€
2,34
M€ 2 2
1,98
M€
0
Patents in the Amounts invested in Start-ups created
portfolio (total) maturation during during the year
the year
2012 2013 2014 2015 2016 2017
SPOTLIGHT
ANTENNE IRM
A turning point for clinical MRI
Researchers from Multiwave Innovation and Institut Fresnel
successfully conducted a maturation program in partnership. The
aim is to manufacture a prototype emitter antenna for the head
in accordance with Clinical MRI standards. The new proposed
approach paves the way for more accurate in vivo diagnostics than
ultra-high field clinical MRI imaging (7 Tesla) such as the early
detection of pathologies like Parkinson’s disease.
Institut Fresnel (UMR 7249), Institut d'Imagerie Biomédicale (I²BM, CEA)
2017 Annual Report I page 9
5 YEAR SPECIAL EDITION 2012-2017
PONT D’AVIGNON MINOPAIN
3D digital reconstruction of the Pont Disk for assessing acute pain
d’Avignon (Avignon Bridge), in newborn babies
a 400 years virtual leap into the past Towards greater consideration of pain
This digital reconstruction comprising a cloud of 6 management in children, this innovation
billion scanned points revives the World-famous improves pain management during care
bridge over the Rhône and its 22 arches, as they in babies less than three months old, by
existed in medieval times facilitating their pain assessment.
Modèles et simulations pour l’Architecture et le Patrimoine (MAP, UMR Assistance Publique – Hôpitaux de Marseille
3495), Centre Européen de Recherche et d’Enseignement des Géosciences
de l’Environnement (CEREGE, UMR 34), Centre Interuniversitaire d’Histoire
et d’Archéologie Médiévales (CIHAM, UMR 5648), Laboratoire d’Archéologie
Médiévale et Moderne en Méditerranée (LA3M, UMR 7298)
SPOTLIGHT
GENERIC TRANSDUCER
The World's smallest gas sensor for
measuring air quality
A miniature gas sensor composed of sensitive
heated metal oxide layers enhanced by a patented
transducer to detect numerous gases and vapors
such as carbon monoxide, carbon dioxide, ozone and
VOCs.
Institut Matériaux Microélectronique Nanosciences de Provence (IM2NP, UMR
7334)ECODIGUE Innovative breakwater concept to improve coastal protection EcoDigue is a new approach to coastal protection derived from the metamaterial theory, this new technology is a structure composed of multiple concrete cylinders arranged specifically to reduce wave amplitude by more than 50%, limiting coastal erosion while preserving the marine ecosystem. Institut Fresnel (IF, UMR 7249), Institut de Recherche sur les Phénomènes Hors Equilibre (IRPHE, UMR 7342)
2017 Annual Report I page 12
ECOSYSTEM
Claude GIRARD In 5 years of existence, the collective support of academic shareholders alongside
Director of the research valorization the State has allowed the SATT to succeed in their implementation and to acquire
program within the Secrétariat unquestionable legitimacy in the landscape of valorization of French research. The
Général Pour l’Investissement, figures speak for themselves: in the latest report they declared having identified
Department of the Prime Minister's 6,300 laboratory inventions, filed 1,818 patents and signed 526 operating licenses,
Office financed more than 1,700 maturation projects (proof of concept, change of scale...),
filed 2,200 patents and signed 634 operating licenses, creating growth of 25%
between 2016 and 2017. By promoting the work carried out in 67 universities
and 160 research institutions, this one-of-a-kind tool also enables the creation of
many start-ups (214 to date). We are also starting to measure their impact. Initial
analysis shows that companies using technologies matured by a SATT improve
their turnover by 4% in the short term. From this point of view, they meet their
assigned objective: to boost the competitiveness of our economy while bringing
research in reach of the companies.
To get there, they had to break new ground, capitalize on pre-existing skills and
develop complementary ones to identify the most relevant applications. This is why
the government has given them five more years to balance the budget and sustain
their existence. Some are more advanced than others, because they have benefited
from an early start, fertile grounds in terms of R&D, shareholders willing to work
together, they have implemented effective processes and they have close-knit
teams led by managers capable of tackling complex situations. This is the case of
SATT Sud-Est, which combines two major IDEX labeled (“Initiative d’Excellence”)
university centers, Marseille and Nice. It displays performance indicators in-line
with the SATT model in a powerful research network, since it has even made a
Companies using profitable start-up transfer operation.
technologies matured by a Beyond this breakthrough, the new stage of growth and consolidation notably
SATT improve their turnover involves greater coherence with local development and innovation policies,
resulting in the Regions entry into the SATT capital to give their action even more
by 4% in the short term
impact in the territories. Here again, some are more advanced than others such
as Occitanie and Brittany, the Pays-de-la-Loire or Alsace and this movement is
expected to grow as long as the Regions share the diagnosis established by the
JUPPÉ-ROCARD Commission, on the challenges of maturation to valorize the
research work of the most promising laboratories in terms of economic impact.2017 Annual Report I page 13
5 YEAR SPECIAL EDITION 2012-2017
Philippe ADNOT "According to their location and history, the performance of public research
Senator representing the Aube valorization structures is uneven and most of them have yet to prove themselves.
department, Member of the Finance 14 SATT are now operational in almost the entire territory and generate significant
Committee, author of a budget structural costs, including more than 800 jobs, 500 of which are permanent. In
control report on the SATT terms of activities, they are generally on the rise, but the resulting revenue remains
in July 2017 very modest, with 82.5 million euros over the entire 2012-2016 period, with only
16 million euros issued from technology transfer (the rest from other services they
perform). It is still too early to judge their relevance, but it would probably have
been more effective to develop a smaller number of SATT presenting the best
performance guarantees of experimentation before generalizing them, or even
entrusting the maturation expenditure to well established valorization services
rather than creating new structures.
It appears that a key factor in their success is the capacity of their management
to build trusting relationships with universities and research organizations (CNRS,
Inserm...) in their territory and their ability to build successful organizations. It is the
precondition of a full commitment on the part of the ecosystem of local innovation.
On this point, SATT Sud-Est is one of the best armed. Its president addresses the
world of research as well as that of companies. It is at the interface of valorization
and many of its best practices deserve to be scattered.’’
SATT Sud-Est is at the
interface of valorization and Georges LEONETTI
many of its best practices
Vice-President of
deserve to be scattered the Provence-Alpes-Côte d'Azur
Regional Council, In charge
of Education, Higher Education,
Research, Health and Well-being
"Creating a link between the academic and economic world is a priority. It is included
in the framework of the economic development pattern as well as that of national
education, research and innovation in the region. We observe with appropriate
attention and support all actions to valorize research. In this context, SATT Sud-Est
has positioned itself as a key player to create this link in the heart of this changing
world. It enables a true continuum between fundamental research and economic
valorization. For a long time researchers did not feel concerned by economic outcome,
this is no longer the case today. Even better, regionally we now have numerous tools
and structures. Ultimately, better coordination among all would enhance collective
efficiency. The Cité de l’Innovation d’Aix-Marseille is perhaps this link, enabling the
establishment of a one-stop shop and offering extensive information to researchers
and entrepreneurs. SATT Sud-Est can intervene as an inseparable structure at the
Cité de l'Innovation by cementing the actions undertaken. As such, its business
model will inevitably evolve. In relation to SATT, the PACA Region, without being a
stakeholder could eventually become a member of its shareholding. Real dynamism
characterizes our region and SATT Sud-Est contributes to this. It is no coincidence that
its president, Laurent BALY, has also been elected president of the SATT Network."
SATT Sud-Est ensures
the continuum of innovation2017 Annual Report I page 14
ECOSYSTEM
Eric BERTON
Vice-President Innovation
Valorization, Aix-Marseille
Université
"SATT has stumbled and stammered, they have experienced failure and have struggled
to find their position, but in five years, the difficulties they had to overcome has forged
their character and professionalized their actions. They are now tailored for international
competition with staff trained in valorization, focused on that one task now framed by
perfectly codified provisions. Our territorial SATT is a sure and effective tool in which we
have enough confidence to entrust it with a large part of our own technology transfer
policy. With it - through it - our public research has changed dimensions. We can now
negotiate as equals with institutions in other countries that are interested in our work.
The visibility of our innovation abroad has changed. SATT has also gained expertise in
pedagogy, to explain to researchers that valorization does not divest them of their works
but participates in changing the world. They recognize it in this way, if we are to believe
the growing number of innovations that enter into this dynamic of transfer, essentially
in health, science and technology and increasingly in humanities and social sciences.
The opening of the Cité de l’Innovation d’Aix-Marseille (CIAM) created by Aix-Marseille
Université, the Métropole AMPM and supported by the South Provence-Alpes-Côte
d'Azur Region, will extend this state of grace by bringing together all the players and
valorization tools, SATT, but also investors and other incubators and accelerators around
SATT has changed the a one-stop shop. Accordingly, the metropolis will have a symbolic site for creation at its
dimension of public research disposal."
‘‘The strategic partnership we have concluded with SATT Sud-Est since January 1st, Marc MUSELLI
2012, has already allowed us to change the scope in the field of research transfer from Vice-President of the Research
our laboratories. Our institution is a university on a human scale, with 4600 students, Commission, Università di Corsica
almost 160 research professors and 7 laboratories certified by the major national research Pasquale Paoli
organizations. However, our objective is simple: to valorize the technologies resulting
from fundamental research and associate them with companies, in the long term, to
create activity and qualified employment. If possible in Corsica, where the entrepreneurial
fabric is more than 90% made up of small businesses. Specifically, staff recently made
available by SATT Sud-Est to the University, work closely with our correspondent
in the Department of Research and Transfer to detect technologies susceptible to be
valorized. The University of Corsica has chosen a strategy of specialization and has
identified high value-added scientific niches specific to the territory. These include the
energy sector, marine resources with a state-of-the-art fishing platform, information and
communication technologies, natural resources, the field of law and business assets, as
well as research in relation to human health (virology, epidemiology). To SATT, we have
brought nineteen invention disclosures, two patents and scientific support for the creation
of a start-up, Stepsol focused on the development of a controlled energy photovoltaic
storage production solution. SATT action has enabled us to become more competitive
in the markets. The Stella Mare platform, one of the leading figures of the University
of Corsica and the CNRS in marine and coastal ecological engineering research, has
established this link for several years between research products and companies. It is
part of a virtuous process of transfer of scientific results and provides answers to the
needs of marine professionals to support the sectors of the "marine" economy. ’’ The University of Corsica
has chosen a strategy
of specialization2017 Annual Report I page 15
5 YEAR SPECIAL EDITION 2012-2017
Claude SCHOONHEERE
President of Réseau
Entreprendre Provence
‘‘The informal relations maintained for several years between SATT Sud-Est and Réseau
Entreprendre Provence have resulted in an established partnership since October 2017.
For too long our two worlds did not communicate. The SME is completely out of touch
in its relations with research. Now, however, the relationship between researchers and
business leaders has been strengthened. Scenarios are scheduled from research pitching
during dedicated meetings. A means for both to work together and expand market
opportunities. At a first meeting, approximately 30 business leaders from diverse sectors
and 10 representatives from SATT Sud-Est took part in a test meeting. The dual ambition
aims to valorize public research inventions from the PACA and Corsica Regions, to support
their transfer to regional companies, in order to increase their competitiveness and create
value and employment. At present, the reaction is positive; some business leaders have
positioned themselves on new opportunities. Secondly, the development of contacts
and a new network has caused a "domino effect". If researchers are looking for market
opportunities for their research, for their part, business leaders are looking to identify the
fruits of research that they could, in co-maturation with SATT, transform into innovations.
These workshops that we want to implement with SATT Sud-Est, must enable the effective
meeting of these two types of needs. This new challenge consists in connecting the need
Réseau Entreprendre Provence and the capacity, so that researchers and entrepreneurs can build the world of tomorrow.’’
and SATT Sud-Est initiate a
new culture of policy dialogue
Emilie ROYÈRE
Director of the Eurobiomed
‘‘Between the Eurobiomed competitiveness cluster and SATT, the history is old competitiveness cluster
and the relationship sustainable and rooted. Since their inception, the SATTs have
been an obvious partner in linking the academic and industrial worlds. Several joint
actions have been developed between SATT Sud-Est and Eurobiomed. The first
is based on the transfer of technologies to allow our network of companies to be
aware of the technologies owned and valorized by SATT and that may interest them.
Another anchor point common to both is entrepreneurship and support structures.
Our committee of investors, "Invest in Biomed" which held its third edition in the
fall of 2017 enabled us to bring together some twenty life sciences specialized
investors. A dozen innovative companies selected and supported by Eurobiomed,
SATT Sud-Est and AxLR in the most diverse sectors: diagnostics, medical devices,
drugs and e-health, were presented in order to stimulate participation. 6 months
later, the bottom line is, 4 discussions are progressing and most investors return
year after year. Of course, there are some fantastic victories. Another success
this year was the signing of a license granted by SATT Sud-Est to a Eurobiomed
member by the Eurobiomed cluster.‘’
Old ties, joint actions and
tangible achievements2017 Annual Report I page 16
THE INTERVIEW
Christian ESTROSI In recent months, Métropole Nice Côte d’Azur has piloted
and won numerous calls for projects from the European
Mayor of Nice, President Union, such as IRIS and obtained several million euros to
of Métropole Nice Côte d’Azur, set up experiments to make life easier for the inhabitants.
Deputy President of the Our proactive and ambitious strategy is working: Nice
Provence-Alpes-Côte d'Azur Region Côte d'Azur has never had as many companies in its
history. Today 66,191 are developing here, and the share
of companies pledging to these new industrial sectors,
is increasing. This does not prevent us from being
continuously acknowledged as one of the most attractive
cities in the World for the beauty of its landscapes, the
splendor of its monuments, the exceptional diversity of its
cultural offer. Tourism remains one of our greatest assets,
and in this area, innovation also has its role to play.
As winners of the "Territoires d’Innovation de Grande
Ambition" call for expressions of interest, on which sectors
should Métropole Nice Côte d’Azur and Université Côte
d’Azur capitalize on?
To capitalize, we must continue to take the lead in a
number of sectors, in order to attract investment and
The winners of the "Territoires d’Innovation domestic and foreign talent and to establish and develop
de Grande Ambition" call for expressions French and foreign companies in our territory. To specialize
of interest, Métropole Nice Côte d’Azur means to coordinate and focus our forces, those of all
and Université Côte d’Azur shall notably local authorities and all the players in the economy.
focus their innovation efforts on energy First, we have a network of local start-ups with very
high potential and we must do everything to continue to
transition and connected health.
nurture their creation and help them to conquer markets.
Commentary. This is the aim of the Nice Côte d'Azur business incubator,
labeled CEEI, which I created in 2008 and which has
How important is innovation for Métropole Nice Côte
generated 119 start-ups and more than 600 jobs to date.
d’Azur?
The operation of interest "National Eco-Valley", which I
From 2008, I initiated the industrial transformation initiated to the west of the City on 10,000 hectares and
and economic diversification of the of Nice Côte d'Azur 15 communes, is in full development: the rise in strength
territory. As a former Minister of Industry, I realized early of the Nice Méridia urban technopolis and the completion
on that the new innovation- and digital-based sectors had of the Grand Arenas international business district,
great potential for growth, job creation and improvement accompanied by the simultaneous creation of the T2 and
of the living environment of the inhabitants. The smart T3 tram lines make this part of the city the backbone of
city is the guideline for development of our territory and innovation in our territory.
improvement of everyday life. This guideline is at the Nice Côte d'Azur is also a pioneer in the energy transition
service of the first of my priorities: the well-being and sector. For the past few months, we have hosted the only
quality of life of the inhabitants. French demonstrator of the European Interflex project,
supported by the Enedis group. We are experimenting on
The European Union itself recognizes that Nice Côte an industrial scale with new solutions for energy storage
d'Azur is now part of the elite of global smart cities and and electrical flexibility. An authentic and promising
labeled us "Innovation Ambassador City of Europe" in ecosystem is taking shape in this sector.
November during the Lisbon WebSummit.2017 Annual Report I page 17
5 YEAR SPECIAL EDITION 2012-2017
I also strongly believe in the development of the
connected health sector. In the Côte d'Azur, we have a
quality ecosystem of great diversity. We will build Delvalle
2, the new connected health headquarters. I shall install Can you tell us which solid stakeholders of the
a residence for interns with 75 lodgments for students territorial ecosystem can Métropole Nice Cote
and researchers, a nursery of specialized start-ups and d’Azur rely on? In particular, what role does
a business hotel on 3,000 m². This is the first step in Public Research and offices related to technology
making Nice a European City of Health which aims to transfer play in this approach?
create activity and employment in the eastern sectors of
Nice. Making every effort to develop this sector will also
The strategic role of Métropole
allow us to innovate and even more to permit the people
of Nice to preserve their health, their autonomy and to Nice Cote d’Azur is to support the
age well. virtuous territorial eco-context of
innovation. I have been working
Can innovation be a driver of the well-being of the
inhabitants and the sustainability of a territory, in hard with my teams to get the
particular of the Métropole Nice Cote d’Azur? large industrial groups, local start-
The priority of innovation must be above all the well-being ups and education and research
of the inhabitants. The Métropole has become the leader players to work together in this
of a territorial innovation whose citizens are beneficiaries
direction.
but also stakeholders. In my opinion, we have entered
a unique cycle of growth and innovation. My role as a
politician is to put these new technological resources at SATT Sud-Est is one of those
the service of our fellow citizens to offer them, whether
they live in town or in our villages, a superior quality of
stakeholders we can rely on. We
life. have worked together in close
Territorial solidarity is important to me. Nice Côte d'Azur and constant connection with
gives rural communities the means to develop and equip
themselves with innovative equipment to halt rural
Université Côte d’Azur, so that the
desertification and make life easier for the inhabitants. Prime Minister selected Nice Côte
For example, Métropole Nice Côte d’Azur has invested d'Azur as a "Territoire d’Innovation
and committed to renew roadside lighting in its villages.
The new generation lighting with 100% LED technology,
de Grande Ambition" within the
makes it possible to illuminate the public space as well framework of the Programme
as to consume less energy and also preserve the fauna d’Investissements d'Avenir.
and our exceptional biodiversity. Innovation is therefore
a major lever and essential to the development and
sustainability of our territories.2017 Annual Report I page 18
THE DIRECTORS
REPORT
Stéphane BERGAMINI
Director of the Technology
Transfer Department In 2016, a new dynamic was launched within SATT Sud-Est via an internal
operational reorganization. Now organized around ad hoc management. Around
fifteen Technology Transfer Managers conduct the detection, maturation and finally
the marketing and licensing of inventions from public research laboratories. SATT
has refocused on its core business to generate value and growth in its territory.
The results speak for themselves: SATT, serving its shareholders and founding
members, appears more comprehensible, more reactive and more agile, in line with
the demands and pace of the markets it addresses. Internally, the organization has
also been redesigned for efficiency and simplicity, with an appropriated managerial
strategy.
The focus on five areas of interest is maintained: Health & Life Technologies;
Environment, Energies & Territories; Industrial Processes; Connected Information
Society; and Culture, Heritage & Digital Humanities.
The Technology Transfer Managers rely on the marketing studies issued by the
Operational Marketing Officers from the Marketing & Communications Department,
they develop an operational vision of what must be broken down for each application:
industrial property, valorization, financing, validation of the technology... They follow
a tighter decision-making process: Intellectual Property Committee, Investment
Committee and then Board of Directors to endorse the decision.
Follow-up measures were also set up to measure SATT performance and impact,
A new organization all actions carried out resulted in the creation of 135 jobs in the territory last
refocused on our core year. Consequently, it is on these foundations that we will make 2018 a year of
business consolidation and development.
250 laboratory visits
in 2017
19 maturation
projects
3,45 M€ invested
in maturation projects2017 Annual Report I page 19
5 YEAR SPECIAL EDITION 2012-2017
Anastasia HOVANESSIAN
Led by Anastasia HOVANESSIAN, the role of the Marketing & Director of the Marketing
Communication Department, at the heart of SATT Sud-Est's & Communication Department
mission, is to establish the strategy for promoting SATT Sud-
Est's projects. A process that is built step by step: from the
validation of an innovation, to the market study through to the
maturation and search for future customers. An essential work
carried out jointly by the Technology Transfer Managers and
the Operational Marketing Officers since the reorganization of
SATT Sud-Est at the beginning of 2017, in order to maximize
the chances of valorization. The Operational Marketing officers
ensure the economic vision of the projects and accelerate
their transfers, by working on the market studies up to the
prospection of future licensees.
For Anastasia HOVANESSIAN "An innovation is an invention
that has found its market" Consequently, a detailed follow-up
of the different project phases to finely analyze the innovation
stakes, the potential customers and the development
possibilities is conducted. "It is a question of bringing together
and matching the scientific projects with the industrial
requirements. Two ways of valorization are possible, the
transfer of the operation of an invention to an industrialist
in order to meet their requirement or if the researcher
An innovation is an invention
has entrepreneurial ambitions, the creation of a start-up."
Anastasia HOVANESSIAN is also involved in the monitoring
that has found its market
of these start-ups, the SATT Sud-Est shareholding and works
with the ecosystem for the correct development of these
young companies, in order to transform these projects into a 50 market analysis projects
in 2017
success. "The success of a start-up, created on the basis of
innovations stemming from public research, depends on the 3 market analysis projects
in 2017
networking between the regional structures, incubators and
Bpifrance. Our role with these diverse structures consists in
providing project leaders with our tools and skills in terms of
4,4 M€ raised by start-ups
since 2012
development strategy, input market or linking with investors.
The sale of one of these start-ups, for several million euros last 45 jobs created in start-ups
since 2012
year, is just one example."
All these actions need to be acknowledged and recognized 1 start-up company
sold since 2012
by the economic world. Therefore, the promotion of public
research in the territory takes place through a calculated
communication strategy. It is necessary that the regional
research institutions, the mission, the SATT Sud-Est actions
and the licensee companies are also valorized by targeted
communication strategies. The Marketing & Communication
Department works to promote the success of projects and the
influence of regional public research.2017 Annual Report I page 20
THE DIRECTORS
REPORT
Sarah DAHL
Director of the Legal &
Intellectual Property
Department For the SATT Legal & Intellectual Property Department, the daily routine is quite
varied. With a team at the headquarters in Marseille and a branch in Sophia
Antipolis, to interact over the entire territory, the department led by Sarah DAHL
has a cross-functional team composed of Patent Engineers specializing by
themes, two Intellectual Property Assistants, Lawyers specializing in intellectual
property and licensing and two Legal Assistants. Their mission? To secure the
transfer activity and achieve the 30% turnover target, to protect and optimize
the quality of the industrial property titles, reduce delays and control intellectual
property costs. From the invention disclosure to the license, there are numerous
intermediate steps. To secure the transfer process for each invention disclosure,
the establishment of fifteen contracts as well as the patentability analysis or the
analysis of software codes as well as freedom to operate are required. "Our role is
to optimize the transfer, quality is a finality," confirms Sarah DAHL. Which, in the
process requires the demonstration of operational creativity in the face of complex
assemblies and involves the contracting of strategic partnerships. Consequently,
one of the challenges is to simplify processes to shorten deadlines while maintaining
maximum security. Hence, the concept of automated lead-time to better manage
each application. "This is also the advantage of the ERP, which enables information
sharing but also monitoring and alerts". To be at the heart of the projects and ensure
close follow-up with the Technology Transfer Managers. "Collective intelligence is
An increase in activity, with our strength. A project team intervenes with common indicators for each invention
projects that require real disclosure," continues Sarah DAHL. The implementation of a quality approach this
operational creativity year is expressed by this drive; the in-house training has also been strengthened so
that everyone gains in performance and competence.
46 intellectual property titles
filed in 2017
29 patents and 17 software
300 intellectual property titles
filed since 2012
229 patents and 71 software2017 Annual Report I page 21
5 YEAR SPECIAL EDITION 2012-2017
Within SATT, the Administrative & Financial Department managed by Olivier RANDOIN Olivier RANDOIN
is on all fronts. The increase in turnover last year to 3.4 million euros was partly due to Director of the Administrative
the sale of a start-up. It remains however, on an upward trend, with over 30% growth on & Financial Department
average each year. The reorganization of the services started in 2016 and completed in 2017
reported positive results. On the program, transversality, which fosters communication
between departments through the implementation of a dedicated tool, an ERP with the
objective of also streamlining the flow of information from shareholders. "The challenge
is to be positioned upstream and downstream of innovation and promote the continuum of
the public funding from the "Programmes d’Investissements d’Avenir". We sell products
that do not exist in markets that are yet to be found. It is often difficult to develop a
technology that has not yet been created," continues Olivier RANDOIN. His department
undertakes several missions: the preparation and monitoring of budgets with the analysis
of expenditure and time scales, purchases on projects, the interpretation of data in order
to set up activity indicators common to SATTs and the accounting justification during
situations and closures. The demands and justifications for European grants are also a
significant part of their business. The first wave of state funding of 78 million euros - a
billion euros across France - is spread over 4 tranches. The second tranche was crucial,
it demonstrated SATT's ability to organize itself, to create value to increase turnover.
The current challenge is to obtain the third tranche of three-year funding still worth €29
million, which will put SATT on the ultimate path of self-financing. Account keeping Our turnover is growing
involves precise audits, the justification of each expense and the demonstration of steady
turnover growth. A second burst in funding is looming in 2021. Of an overall amount of
200 million it will be reduced compared to the initial budget. What about afterwards? Budget 2017
over 9 M€
SATT is positioned as an essential strategic interface. The projection is anticipated to
2030 with a risk analysis on each project. With the knowledge that if IT and engineering 2 500 invoices processed
projects are successful in the short term, those for example, in life sciences involve long- each year
term vision, 10 years on average. "Each project receives a risk score, with a high and low
Over 1 000 projects
margin. In order to meet the Court of Auditors, the Senate Financial Commission and
monitored in the ERP
European controls, we need to ensure the follow-up and good day-to-day management
and consider large scale deployment".
ERDF funds for maturation projects
Since 2013, the European Regional Development Fund supports the maturation of SATT Sud-Est projects. Over the 2013-2017
period, €7 million have been mobilized for the development of innovation and information. "Two million euros of expenditure
has been made available. We are currently preparing the documents for the remaining 5 million" continues Olivier RANDOIN,
Chief Financial Officer at SATT Sud-Est. Certainly, the European Regional Development Fund, requires rigorous administrative
follow-up. It is monitored and controlled every year by the European Affairs Departments and the Provence-Alpes-Côte d’Azur
Regional Council Managing Authority. The funds are allocated to maturation projects that address strategic areas of activity:
cultural industry, tourism and digital content, smart and sustainable mobility, security and safety risks, energy transition and
energy efficiency as well as health and food. "It may also concern Europe's key generic technologies, the nanotechnologies,
microelectronics, biotechnology, photonics, advanced materials and advanced production systems, which account for 80-
90% of our business", resumes Olivier RANDOIN. The accounts will be finalized in 2018 and the next installments spread out
over the coming two years.COMMUNICATIONS
SATT EVENTS
My Innovation Is, valorization 2.0
In October 2016, the first edition of the In 2017, two innovation
"My Innovation Is" event provided an superheroes were rewarded: Vito
opportunity for researchers and Ph.D. CIULLO's project, a Ph.D. student
students to highlight the innovations at Université de Corse, he equipped
of tomorrow. The principle: a 3 minute a drone with a vision device to
pitch in front of entrepreneurs and measure the spread of forest fires;
investors to secure SATT Sud-Est pre- and Jean-Manuel RAIMUNDO's
maturation support with a maximum project, Professor at Aix-Marseille
value of 20,000 euros. For the first Université, it concerns the
edition focusing on "living better", two development of smart coatings
research projects and one start-up with antibiotic properties to reduce
oriented project were selected, and four candidates decided the risk of nosocomial infections in
to valorize their research work and therefore approached implants.
the SATT teams to investigate their projects. One winner,
Stephan GUIGNARD, Lecturer at the Institut Universitaire des
Systèmes Thermiques Industriels, conceived a marine turbine
concept, which improves power generation performance in
remote areas, it has since been valorized through a license
granted to the start-up “VH quatrevingtreize” created by the
researcher. See My Innovation Is... 2017
on YouTube®
Invest in Biomed
Medicine-targeted Each sought funds of between €2 "The relationships established in
investment and 5 million from a dozen investors. previous editions, which continue
2017 was the 3rd edition for this These events work! For the first Invest beyond the pitch, confirm that Invest
annual meeting of private investment in Biomed edition, PhysioAssist in Biomed has become a key event in
in biotech/medtech companies in the for example accomplished a €6 the South, bringing public research
south of France, organized by the million fundraiser with Mérieux and private health investors closer
Eurobiomed competitiveness cluster Développement, an investment together. Our current ambition is to
and SATT Sud-Est, with the support company specializing in the health capitalize on ambitious fundraising,
of SATT AxLR. and nutrition sector. and accelerate the launch of innovative
"We have built a relationship of trust treasures from public research in the
Ten innovative companies with major life sciences investors Provence-Alpes-Côte d’Azur, Corsica
specializing in diagnostics, who come to Eurobiomed for and Occitanie Regions" adds Laurent
medical devices, drugs and companies that have been selected BALY, President of SATT Sud-Est.
e-health had been selected and qualified through a proven
for applications in fields as process. The financing of Biotech/
diverse as oncology, infectious Medtech companies is at the heart of
diseases, neurology and our support program for growth and a
orthopedics. priority for Eurobiomed," says Émilie
ROYÈRE, Director of Eurobiomed.
ZOOOOOM - 5 years of success
In May 2017, SATT Sud-Est was nominated for the 2017 GUV (Global University
Venturing) awards ceremony in London, in the GUV Tech Transfer Unit of the Year
award category.FOCUS HUMANITIES & SOCIAL SCIENCES
Humanities & Social Sciences can also be protected
On September 21, 2017, the INPI patent: copyright, trademark law for protected. Fighting this misconception
organized a training course on designs or models, protection related is now a priority for SATT Sud-Est to
intellectual property rights in to software and databases... These show, with examples, the value of HSS
Humanities & Social Sciences for Intellectual property titles are often innovations.
Ph.D. students and researchers in soft less well known or less well understood
sciences. There is an arsenal of legal by researchers who too often imagine
tools for non-technological innovations that their innovations - because they
as effective and acknowledged as the are not technical in nature - cannot be
Innovatives SHS: Humanities at the heart of valorization
On May 17-18, 2017, a hundred or so innovations in Humanities & Social Sciences from
public research laboratories all over France and beyond were presented at the third
edition of the SHS Innovatives exhibition, organized at Parc Chanot in Marseille under
the leadership of the Institut National des Sciences Humaines et Sociales (INSHS).
A joint SATT network stand enabled HSS valorization officers
to host a large audience. The joint organization in the agora of
an awareness session of SATT support for innovative projects and their transfer to
the socio-economic sphere was the occasion to detect new innovations.
The Exhibition's Wall of Images (picture), which presented stand organization by theme is an innovation from UMR
7303 TELEMME (Aix-Marseille University CNRS) and supported by SATT Sud-Est; as well as the T-CREATIF
platform sponsored by the UMR 7318 CERIC-DICE (Aix-Marseille Université CNRS) or finally the "MINOPAIN" disk
from the AP-HM Maternité de la Conception department, all benefited from an exhibition stand at this third edition
of Innovatives SHS.
SATT AT THE SERVICE OF ITS SHAREHOLDERS
SATT provides services for public research institutions in the territory to raise
awareness of innovation valorization
Several types of services have been completed since 2012:
Days with researchers or doctoral schools: 8 days of awareness were conducted between 2016 and 2017 including
"La matinée de la Valorisation: I protect, I publish, I innovate" organized with SATT Sud-Est on the occasion of
the awareness raising day for the 8th Euro-Mediterranean doctoral fellowships, for the Université de Toulon, or
the awareness days for business creation jointly organized and hosted with the CNRS and the Impulse Incubator.
SATT Sud-Est conducted management of the communication media, notably for Aix-Marseille Université:
SATT Sud-Est responded The AMU Entreprendre website
to the Aix-Marseille Public research is an effective
ENTREPRENDRE avec Aix-Marseille Université
Université request by accelerator for businesses. SATT
creating the Innovation Sud-Est, In collaboration with the Incubator Belle de
Guide describing the Mai, has created a training course for Aix-Marseille
tools and circuits of Université, it studies the devices to transform
innovation, patent researchers into entrepreneurs or solid players of the
application and setting up a business. This guide is economic and industrial world or to facilitate access
intended for research professors and students. to public research for start-ups looking for innovative
projects to develop their business. Accordingly,
The guide is available through three courses aimed at researchers, startups
on the Aix-Marseille University website and students, the Entreprendre AMU site facilitates
the integration of public research into the start-ups
of tomorrow.
Visit the website ENTREPRENDRE
with Aix-Marseille Université2017 annual report I page 24
MATURATION TRANSFER
THE KEYS TO VALORIZATION
Transfers: laboratory creativity goes
from strength to strength
All the technology transfer performance indicators have turned green in 2017. After
the first years of fine-tuning, the valorization tools are now running at full capacity: by
multiplying their number of visits (250 last year), the Technology Transfer Managers
detected a cumulative total of 918 projects giving rise to a total of 214 patent filings
since the creation of SATT. The year 2017 was especially productive: 109 invention
disclosures (2nd best year after 2014), 26 new patents filed, 19 new licenses signed, 3
start-ups created in partnership with incubators... Even better, the "maturation transfer
rate", which measures valorization effectiveness established at 24%. To achieve
this result, SATT Sud-Est multiplied its marketing operations by participating in 26
congresses (Vivatech, BioFIT, Medtec Europe...) but it spent less than usual: only 3.5
million euros committed to maturation (an amount now "stabilized", certainly turned
towards a more qualitative approach), down by half compared to last year, whereas
the amount billed on intellectual property assets stands at 3.3 million euros (against
1 million in 2016). In all, its action has enabled the creation of 135 jobs.
IN FIGURES (cumulative from 2012 to 31/12/2017)
918 projects detected 139 maturation
projects 22,7 M€
committed
592 disclosures
invention
91 signed
licenses
6,4 M€
214 portfolio
patents in the
17 created
start-ups
billed on assets
Maturation Co-maturation License Sub-license2017 Annual Report I page 25
5 YEAR SPECIAL EDITION 2012-2017
ZOOOOOM - 5 years of success
SRGOLD, RAMAN microscope
INDUSTRIAL
a golden opportunity
This new instrument provides new information on the
chemical bonds in biological samples.
PROCESSES Co-owned by the CNRS and Aix-
Marseille Université, a license on
SRGOLD technology for Stimulated
Raman Gain Opposite Loss
Detection, protected by a patent
was granted by SATT to HORIBA
FRANCE SAS, a French subsidiary
Nanotechnologies of the Japanese group of the
same name. The invention by the
SRGOLD Sébastien
MOSAIC team at the Institut Fresnel
An instrument to detect "crooked atoms" VERGNOLE, RAMAN led by Dr. Hervé RIGNEAULT,
Product Manager at CNRS Research Director, focuses
What is it? A RAMAN microscope with improved sensitivity and contrast. HORIBA FRANCE on the stimulated Raman market
SAS in microscopy and endoscopy. Its
What does it contribute? The so-called stimulated Raman scattering interest: obtaining information on
technology called "SRGOLD" makes it possible to obtain information on chemical bonds in biological samples in order to diagnose
pathologies, without resorting to phosphorescent staining.
the chemical bonds in biological samples (tissue, cells...) without marking The goal is to gain at least an order of magnitude on
or staining. the minimum detectable molecular sensitivity in SRS
Who invented it? The Mosaic team at the Institut Fresnel imaging. "After a first meeting with the managers, SATT
and the research team, we have established the main
Who participated?** Aix-Marseille Université, CNRS, Institut Carnot STAR stages of the maturation, which should cover two years,"
continues Sébastien VERGNOLE, RAMAN Product
Who operates the license? HORIBA FRANCE, World leader in Raman
Manager at HORIBA France SAS. The maturation
spectroscopy. It will enable this company to meet the growing demand project aims to develop the SRGOLD microscopy and
for spectroscopy in the fields of medical diagnosis and research including valorize its applications in the field of life sciences and
the identification of tumor margins and endoscopic probes. material sciences in microscopy and endoscopy while
demonstrating its superiority over current microscopy.
"Regular meetings allow us to move forward and measure
the results of a technology that meets the needs of a
growing market in both academic and industrial research
laboratories".
Biomedical
Soft Mixer Algae
Cultivating fragile micro-algae thanks to the
celestial movement of the Earth
What is it? A photobioreactor, "Soft Mixer
Algae" mimics the Earth’s rotation to shake the
culture medium.
For which field of application? To produce
micro-algae and plankton strains of interest Process
for the development of anti-cancer drugs. The Sound attenuation
development program is conducted with the Membrane for low frequency sound attenuation
start-up Planktovie, based in Marseille.
What is it? A low-frequency sound absorption system related to rotating
Who invented it? Institut de Recherche sur
machines thanks to the use of a non-linear absorption membrane.
les Phénomènes Hors Equilibre (IRPHE, UMR
7342) What does it contribute? The technology addresses the problem of
Who participated? Aix-Marseille Université, noise related to rotating machinery such as motors, compressors and
CNRS, Ecole Centrale Marseille, generators.
Université Swinburne (Australie), Incubateur Who invented it? Laboratoire de Mécanique et d'Acoustique (LMA UMR
Interuniversitaire Impulse 7031)
Maturation status: Proof of concept Who participated? Aix-Marseille Université, CNRS, Ecole Centrale
Marseille, Institut Carnot STAR
Maturation status: Application on defined industrial needs
**"Who participated?" Indicates the supervisory bodies in the SATT Sud-Est area for the laboratories mentioned. "Institut Carnot STAR" Indicates the projects from laboratories that are members of the Institut
Carnot STAR. Mention of support by the A*MIDEX Foundation. "Incubateur interuniversitaire Impulse" indicates start-ups supported and funded by the Incubateur interuniversitaire Impulse.2017 annual report I page 26
Transport
Easy Ride
Electric bike conversion for all cyclists Medical imaging
What is it? A device, "Easy Ride" that allows MRI Antenna – To detect neurological diseases earlier, for a more
transforming a classic bike into an electric bike predictive medicine
in one easy move.
What is it? A new generation of MRI antenna to optimize the quality of
For which field of application? A unique bike ultra-high field medical imaging.
solution to go to work on weekdays and
What does it contribute? The possibility of developing clinical MRIs to the
workout on weekends.
7 tesla generation, still reserved for research to detect pathologies earlier
Who invented it? Laboratoire de Mécanique et than current devices.
d'Acoustique (LMA UMR 7031)
Who invented it? Institut Fresnel (IF UMR 7249), Institut d'Imagerie
Who participated?** Aix-Marseille Université, Biomédicale (I²BM, CEA)
CNRS, Ecole Centrale Marseille Who participated? Aix-Marseille Université, CNRS, Ecole Centrale
Maturation object: functional prototype Marseille, Institut Carnot STAR
Who operates the license? Multiwave Innovation, based in Marseille, a
subsidiary of the Swiss group Multiwave Technologies. It aims to equip
about twenty MRIs by 2020.
INDUSTRIAL ZOOOOOM - 5 years of success
Multiwave Innovation paves the way for next-generation MRI
PROCESSES The higher the magnetic intensity of an
MRI, the more accurate the images it
delivers. But beyond 3 tesla, the most
recent device generation that now covers
15% of the market, manufacturers face
a difficulty: interference in the radio
Sensor waves that "print" the image cause
quality degradation. Research adjusts:
Delco 3 – A tool for counting microscopic approximately 70 MRI 7 Tesla (7T) are
particles in clean rooms used for scientific purposes around the
world; but the clinical applications are still
rare (a device was installed in the Mayo
What is it? A device for detecting surface Clinic in October).
contamination by particles moving in free air.
The young company, Multiwave
Transmitter antenna for ultra-high field MRI
What does it contribute? This equipment is imaging (7 Tesla) of the head.
Innovation, created in Marseille last year,
capable of counting and sorting particles hopes to change this condition: after
a maturation program led by SATT Sud-Est with researchers Redha ABDEDDAIM and
according to their size through the use of a Stefan ENOCH from Institut Fresnel, they have obtained the exclusive license of a patent
silica dioxide collection surface. It is particularly jointly owned by the CNRS, Aix-Marseille Université, the Ecole Centrale Marseille and
adapted to the quality control of industrial the Commissariat à l’Energie Atomique. "We have designed emitters based on composite
clean rooms. materials with innovative electromagnetic properties that balance the fields and achieve
optimal image quality," the researchers say. "With the 7T generation, doctors will be able to
Who invented it? Institut Matériaux spot tumors six times smaller than with the 3T devices and pave the way for personalized
Microélectronique Nanosciences de Provence predictive medicine," adds Panos ANTONAKAKIS, president of the company and Elodie
(IM2NP UMR 7334), CEA, Winlight System GEORGET-PARIS, who directs the medical division.
Who participated? Aix-Marseille Université, A significant investment has been made for this first research phase and will continue
to allow the industrialization of this antenna. The company, a subsidiary of the Swiss
CNRS company Multiwave Technologies has raised several million euros from business angels
Who operates the license? The Winlight System to finance this phase and begin marketing. Its goal is to equip around 20 MRIs in 2020,
company, based in Pertuis (FRA), markets this which will provide 5 million euros of turnover.
innovation to detect contaminant or particulate Meanwhile, researchers at the Institut Fresnel continue the work started: in a joint MCube
contamination in its field of activity, the design project, a consortium of ten institutes is now working on whole body imaging.
and development of complex optical systems
for the defense, space, astronomy, industry
and scientific research sectors.
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