Starting your puppy off on the right paw - Smiling Blue Skies

Page created by Erin Gilbert
 
CONTINUE READING
Starting your puppy off on the right paw - Smiling Blue Skies
SPRING/summer 2018
                                                                                                                          COMPLIMENTARY
                                                                                                                                   COPY

                                                                            THE PET MAGAZINE OF THE ONTARIO VETERINARY COLLEGE

Starting your puppy off on the right paw

                                         pettrust.ca

                      FACEBOOK.COM/ovcPET
                      @OVCPETTRUST
                      SNAP, INSTA, TWEET
 Facebook “f ” Logo

                      @ONTVETCOLLEGE
                           CMYK / .eps   Facebook “f ” Logo   CMYK / .eps
Starting your puppy off on the right paw - Smiling Blue Skies
SPRING/summer 2018

                                                                                                   Best friends
                                                                                                        the pet magazine of the ontario veterinary college
                                                                                                                                                               What Pet Owners Need to Know About…
                                                                                                                                                               CANINE INFLUENZA
                                                                                                   What Pet owners need to know about...              3                                                                another flu virus to create a new flu strain that     • If your dog has signs that could be consistent
                                                                                                   Canine influenza
                                                                                                                                                             WHAT IS CANINE
From                                                                                               getting to know...Dr. Tom Gibson                   4      INFLUENZA (H3N2)?
                                                                                                                                                                                                                       could affect both animals and people.                   with influenza (e.g. cough, nasal discharge,
                                                                                                                                                                                                                                                                               fever, runny nose or eyes) and you are taking
the desk                                                                                           pawsitive beginnings: how to start                 5      Canine influenza (H3N2), more commonly known              ”Currently, the risk of the disease spreading to        it to your veterinarian, make sure you call the
of our                                                                                             your puppy off on the right paw                           as dog flu, is an avian influenza virus (bird flu) that   humans is very low,” Weese says. “Controlling the
                                                                                                                                                                                                                       spread through the dog population is what the
                                                                                                                                                                                                                                                                               veterinary hospital first so that they can use
                                                                                                                                                                                                                                                                               measures to prevent exposure of other dogs
Managing                                                                                           For the LOVE of lulu                             8        spread to dogs in Asia in the mid 2000s and more
                                                                                                                                                             widely in some parts of the region, particularly          veterinary community is most concerned with             at the clinic (e.g. admitting your dog directly
Director                                                                                           the tale of minimally invasive surgery:
                                                                                                   advancing care for rabbits
                                                                                                                                                    10       China and South Korea. It was introduced to the
                                                                                                                                                             United States in 2015, and has spread to multiple
                                                                                                                                                                                                                       at this point. If you suspect your dog has been in
                                                                                                                                                                                                                       contact with another dog that has been infected, it
                                                                                                                                                                                                                                                                               to an exam room or isolation area).
                                                                          Kim and harley                                                                                                                                                                                     • If your dog is sick and has been at a kennel,
                                                                                                                                                             parts of that country. The first known canine influ-      is best to contact your veterinarian.”
                                                                                                   passion for pets: ren’s pets gives               12       enza case in Canada was reported in early 2018,                                                                   doggy daycare, puppy class or any other
Spring and summer are popular times of             OVC Pet Trust continues to invest in projects   back to companion animal health                                                                                                                                             event, contact the owner or operator to let
the year for pet owners to welcome a new           that are advancing animal health. From                                                                    when two dogs who were imported from Asia to
animal into their home. Adding a new pet to        investigating the brain activity in epileptic   Life on ovc’s diagnostic imaging service          13      Essex County, Ontario, were diagnosed.                    HOW TO PROTECT                                          them know.
your family can be an exciting, eventful and       dogs, to using a novel virus as a vaccine to    heal, boy:                                                                                                          YOUR DOG FROM                                          • If your dog is diagnosed with influenza or has
demanding time. Hard work and dedication
pays off and ideally your new pet will
                                                   treat cats with breast cancer, to measuring
                                                   disease markers of bone cancer in dogs with
                                                                                                   How your pet may save your life one day
                                                                                                   by Sharon Kirkey, National Post
                                                                                                                                                    16       Influenza in dogs has many similarities to influenza
                                                                                                                                                             in people. Most affected dogs develop typical flu-        CANINE INFLUENZA                                         signs consistent with influenza, it should be
                                                                                                                                                                                                                                                                                kept away from other dogs for four weeks,
become a treasured part of your family and         routine blood samples, our researchers are                                                                like signs such as coughing, fever and runny nose
grow to become a loving, loyal companion.          at the forefront of veterinary medicine to      the vital role of nutrients in my                21       or eyes. While most dogs (like most people with
                                                                                                                                                                                                                        • If your dog is sick, keep it away from other
                                                                                                                                                                                                                          dogs.
                                                                                                                                                                                                                                                                                even if appears to be healthy before the end
                                                                                                                                                                                                                                                                                of that period. Some dogs can continue to
In this issue of Best Friends you’ll find          help the pets we love, live longer, healthier   pet’s diet
                                                                                                                                                             human flu) recover uneventfully, a small percent-                                                                  shed the flu virus for a couple of weeks after
valuable information about how to prepare
for pet ownership from our OVC expert Dr.
                                                   lives. Learn more about newly-funded
                                                   projects to enhance companion animal
                                                                                                   decoding your pet’s body language                22       age of dogs can develop serious, and even fatal,           • If you are out with your dog and see a sick           they recover.
                                                                                                                                                             disease. As of Spring 2018, clusters of the outbreak         dog, keep your dog away from it.
Jason Coe, who recently welcomed a new
puppy named Harley into his family. Be
                                                   health and well-being in Your Gifts at Work
                                                   on page 27.
                                                                                                   ON THE FOREFRONT OF VETERINARY
                                                                                                   MEDICINE: exploring regenerative
                                                                                                                                                    24       have been confirmed in Windsor-Essex, Muskoka                                                                   • Canine influenza can infect cats, but the
                                                                                                                                                             and Northumberland County, with an estimated               • If you have contact with a sick dog, wash            incidence appears to be very low.
sure to read Dr. Coe’s recommendations on                                                          medicine to enhance animal and
informed pet ownership and the human-              I am constantly inspired by all of the          human health                                              200 Canadian dogs infected with the virus as of              your hands, and ideally change your clothes,
animal bond if you’re looking to add a new         creative and generous ways people give                                                                    late March.                                                  before you touch your dog.                         • Vaccination is not a guarantee, but it can
puppy (page 6) or rabbit (page 10) into your       back to OVC Pet Trust. We are so fortunate      decreasing your pet’s risk of stroke             26                                                                                                                         reduce the likelihood and severity of disease.
                                                                                                                                                                                                                        • Most dogs with influenza get over it on their        Ask your veterinarian if vaccination is recom-
home in the near future.                           to have donors and supporters who
                                                   celebrate their love of animals in unique
                                                                                                   investing in discovery
                                                                                                   your gifts at work
                                                                                                                                                    27       DOES CANINE FLU                                              own. As long as they are bright, alert, eating       mended for your dog.
                                                                                                                                                                                                                          and don’t have yellowish nasal discharge,
This past fall, the National Post published
                                                   ways. No matter how you give back to OVC
                                                   Pet Trust, you are truly making a difference,   Saying Goodbye...by dr. renee fleming            28       POSE A PUBLIC                                                veterinarians typically do not provide any
a feature story based on health reporter
                                                   and I sincerely thank you for your support.                                                               HEALTH RISK? The odds                                        specific treatments beyond cough suppres-
Sharon Kirkey’s time spent visiting OVC,
meeting and interviewing our veterinarians,
                                                                                                   ovc pet trust launches new support
                                                                                                   guide for pet owners preparing for
                                                                                                                                                    29       are pretty low, says Dr. Scott Weese, a researcher              sants, if coughing is excessive.
our researchers and our clients. I hope                                                            the loss of a pet                                         and veterinary specialist at the University of
                                                                                                                                                             Guelph’s Ontario Veterinary College. Weese’s
you’ll appreciate reading her article which
appeared on the front page of the national                                                         Colborne street pet hospital gives back          29       primary area of expertise is in infectious dis-
                                                                                                                                                             eases, with an emphasis on zoonotic diseases
newspaper last October. Heal Boy: How Your
Pet May Save Your Life One Day, is included
                                                   Kim Robinson                                    Six Degrees of Separation                        30       – those that can be transferred between ani-
                                                   Managing Director, OVC Pet Trust
as a special insert in this issue. It highlights
the importance and value of the life-saving
                                                   Ontario Veterinary College                      In memory: sully                                 31       mals and people. He has been the leading voice
                                                   University of Guelph                                                                                      in the veterinary community, with public health
and translational health benefits of what                                                          back cover                                                agencies and in the news media on managing the
happens at OVC, and the critical role OVC Pet                                                      #PetTrustPals
                                                                                                   Upcoming Events                                           H3N2 canine influenza virus outbreak since it
Trust plays in supporting these initiatives.                                                                                                                 appeared for the first time in Canada.

BEST fRIENDS MAGAZINE IS PUBLISHED TWO TIMES PER YEAR BY ovc pET tRUST                               tAKE OUR minute                                         Human infections with H3N2 canine
                                                                                                                                                             influenza have not been identified.
                                                                                                     READER SURVEY                                           Weese says the bigger concern
OVC Pet Trust, founded in 1986 at the Ontario Veterinary College (OVC), University                   for your chance to                                      from a public health point
of Guelph, is Canada’s first charitable fund dedicated to the health and well-being                  win a $250 REN’S PETS gift card
of companion animals. The Ontario Veterinary College is a leader in veterinary                                                                               of view is the threat of
healthcare, learning and discovery for the health of all species, including our own.                 GENEROUSLY donated by Ren’s Pets.                       the virus combining with
                                                                                                     wE WANT YOUR FEEDBACK. LET US KNOW WHAT
To learn more or to make a donation visit www.pettrust.ca                                            YOU THINK OF THIS ISSUE OF BEST fRIENDS:

University of Guelph Charitable Registration #: 10816 1829 RR 0001
                                                                                                     WWW.PETTRUST.CA/SURVEY                                                                                                                                                                                                      3
Starting your puppy off on the right paw - Smiling Blue Skies
RESEARCH SPOTLIGHT
                                                                                                      has been associated with a higher than normal
                                                                                                      infection rate. The reasons why are unknown
                                                                                                      but it may be a result of the reduced soft tissue
                                                                                                      coverage in the area where surgery is per-
                                                                                                      formed. Our work on surgical site infections is
                                                                                                      intended to find a way to decrease the chance
                                                                                                      of infection in TPLO, and other surgical patients
                                                                                                      as well. Another area of interest of mine is
                                                                                                      rehabilitation and our pets’ post-operative
                                                                                                      recovery. I have recently become a Diplomate
                                                                                                      of the American College of Rehabilitation and
                                                                                                      Sports Medicine and hope to pursue additional
                                                                                                      research in this area.

                                                                                                      What impact does OVC Pet Trust
                                                                                                      funding have on your research?
                                                                                                      I have been very fortunate to be involved in
                                                                                                      many projects that have been supported by OVC
                                                                                                      Pet Trust. Simply put, OVC Pet Trust is the life-
    Small Animal Surgeon and Associate Professor                                                      line for the work we do here at OVC. If our work
    Department of Clinical Studies                                                                    can have an impact on day-to-day cases that
    Ontario Veterinary College                                                                        general veterinary practitioners see and treat, it
    University of Guelph                                                                              makes it more meaningful for us as researchers
                                                                                                      and for the profession of veterinary medicine as
     Why surgery? I chose a career in                materials can become infected and form
                                                                                                      a whole. Support from OVC Pet Trust positions
     surgery for the challenge and the creativity.   a biofilm, or a slime-like product, that
     You can do the same surgical procedure          resists treatment by many of our first-line      us to be at the forefront of veterinary medicine
     hundreds of times and you never really          antibiotics. We are looking at the possibility   and education and continue to be a centre of
     know what you may be faced with in the          of using a gel containing antibiotics and        veterinary excellence in the world.
     operating room. That’s the thing that           enzymes to prevent surgical site infections
     terrifies me the most about surgery, but        that may result from our use of surgical         Tell us something about yourself
     it’s also the most exciting. We get to fix      implants. Some antibiotics that are most
                                                     effective against resistant bacteria can cause
                                                                                                      that might surprise your
     pets; it’s very rewarding. I love seeing
     students, interns and residents get inspired    damage to the kidneys. We are exploring          colleagues. Twelve years ago I became
     by surgery. I was once a resident myself        the possibility of a local gel therapy that      interested in cycling. In 2010, I rode my bike
     and second-guessed my skills; to watch          could be an option to proactively prevent an     across Canada to raise funds for the Coast to
     our students learn, grow and progress is so
     much fun. Surgery can also be exhausting –
                                                     infection without having widespread side
                                                     effects throughout a pet’s body.
                                                                                                      Coast Against Cancer Foundation, a national
                                                                                                      charity devoted to fighting childhood cancer.
                                                                                                                                                           Starting your puppy off on the right paw
     physically, mentally and emotionally – and                                                       At the University of Guelph, our team has raised
     it can be devastating when, despite our best    How could patients benefit                       almost $250,000 for the organization via The
     efforts, we don’t always win and we don’t       from your surgical site infec-                   Inside Ride, an indoor cycling challenge and
     always have the outcomes we would wish
     for all of our patients.                        tion research? Tibial-plateau-level-             fundraising event dedicated to raise money                      New research shows early socialization is believed to be critical to the
                                                     ing osteotomy (TPLO), a surgical procedure       in support of children with cancer and their
                                                                                                      families.
                                                                                                                                                                      healthy development of puppies. Socializing puppies is most important
                                                     to repair the cranial cruciate ligament (CCL),
     What projects are you cur-                      is the most common joint injury in dogs                                                                          between the ages of four and 16 weeks, and involves helping a new pet
     rently working on? Right now I’m                around the world. CCL is similar to an ante-     Do you share your home with any                                 become comfortable in their new environment by introducing them to
     examining a novel drug delivery system for      rior cruciate ligament (ACL) tear or common      pets? My family has a Boston Terrier x
     patients with postoperative infections along    knee injury in humans, except in dogs this
                                                                                                      French Bulldog named Poppy, and a new addi-
                                                                                                                                                                      many different types of people, spaces and places, pets, noises, sights,
     with a team of OVC experts. Implant-as-         disease is a degenerative process and not
                                                     an athletic injury. About sixty per cent of
                                                                                                      tion, a Standard Poodle puppy named Henry.                      sounds and smells in a positive and controlled way.
     sociated bone and joint infections occur
     when bacteria adheres to the plates and         dogs that sustain a CCL rupture in one hind      My wife (OVC Internal Medicine Specialist Dr.
     screws that we place in a pet’s body. These     leg, will rupture the other. TPLO surgery        Shauna Blois) and I also have six-year-old twin
                                                                                                      (human) boys.
4                                                                                                                                                                                                                                                5
Starting your puppy off on the right paw - Smiling Blue Skies
Why is early puppy                                             “The ‘puppy year’ can be both an exciting and challenging
                                                                   time for owners while puppies adjust to their new lives,”
                                                                                                                                  Advice from the experts                                       New pet checklist
    socialization important?                                       says Coe. “Family veterinarians are an important resource
                                                                                                                                  If you have a new puppy or if you are con-                    Before deciding to get a new pet, it would
    Early puppy socialization is believed to be critical to the                                                                   sidering a new four-legged addition to your                   be beneficial to consider a variety of factors
                                                                   for pet owners and can provide valuable information on         home, OVC experts recommend considering the                   including:
    healthy development of puppies. Socializing puppies is         what activities are considered positive for puppy socializa-
    most important between the ages of four and 16 weeks,                                                                         following:
                                                                   tion, discuss timing and troubleshoot individual behaviour
    and involves helping a new pet become comfortable in           issues. They can help develop a positive reward-based
                                                                                                                                                                                                 Your lifestyle
    their new environment by introducing them to many              training program and also answer questions about intro-
                                                                                                                                   • It’s important to remember that puppies                     Time available to
                                                                                                                                     have an optimal socialization period,                                                                                  The Neurology Service at the OVC
    different types of people, spaces and places, pets, noises,    ducing a new puppy to children or other pets.”                                                                                         dedicate to your new pet
    sights, sounds and smells in a positive and controlled way.                                                                      during which it is imperative your new                                                                                 Health Sciences Centre specializes in
                                                                                                                                     pet has positive exposure to new people,                            Species differences                               providing advanced and emergency care
    Poor puppy socialization can result in fear and sometimes
                                                                   There are many steps pet owners can take to start their           animals, experiences and locations. This                            Your current pet                                  to companion animals. The team sees
                                                                   new puppy off on the right paw.                                   socialization period ranges from the first                          Your new pet
    aggressive behaviour in dogs. Behaviour problems are a                                                                                                                                                                                                  and treats a wide range of disease and
    leading cause of breakdown in the human-animal bond,                                                                             four to 16 weeks of a puppy’s life.                                 Cost of pet ownership                             conditions in pets including epilepsy,
    the relationship and positive connection between pets          Are you thinking of welcoming                                                                                                                                                            spinal pain, weakness, gait changes,
    and their owners. It is estimated up to 50 per cent of         a new puppy into your home?                                     • Positive exposure to different kinds of                                                                                muscle and nerve disorders and a variety
                                                                   If you are contemplating adding a puppy to your home, it          new experiences prepares puppies for the                   Dr. Jason Coe is an OVC Pet Trust-funded researcher. To     of congenital and degenerative nervous
    owners say behaviour issues are the main reason for sur-                                                                                                                                    learn more about how to prepare for pet ownership,
    rendering or giving up their pet to either friends, families   is important to understand what you are looking for and           development of future social relationships                 visit www.beforeyougetapet.com.                             system diseases.
    or shelters.                                                   what your expectations are of your new pet. Research has          and helps to prevent fear in new and
                                                                   shown that the success of a human-companion animal                unknown situations.                                                                                                    One service in particular the Neurology
    A recent study from the Ontario Veterinary College (OVC)       relationship is influenced by whether an owner’s expecta-                                                                                                                                team provides is hearing tests, or brain-
    found puppies who attended puppy classes at less than          tions can be met by the dog and whether the needs and           • Puppy classes provide an excellent oppor-                                                                              stem auditory evoked response (BAER)
    20-weeks of age were less likely to develop negative           lifestyle of the owner and personality of the dog match.          tunity for owner education and puppy                                                                                   testing. BAER testing is used to diagnosis
    behaviour patterns or fear responses to normal events          Owner expectations can relate to the time and effort              socialization and a great way to avoid                                                                                 deafness in pets. Registered Veterinary
    such as noises like thunderstorms and vacuum cleaners,         required in caring for your dog (walks, training, veteri-         serious pet behavioural problems.                                                                                      Technician (RVT) Jennifer Collins is in
    and every day experiences like being placed in a dog crate.    nary visits), the role of the dog in the household (friend,                                                                                                                              charge of administering the hearing
                                                                   protector) and the annual cost of owning a dog. Therefore,                                                                                                                                test and normally sees up to 165 dogs
    “One of the main recommendations for pet owners as a           before choosing a new dog, it is beneficial to think about                                                                                                                               per year.
    result of our study is to take the opportunity to discuss      your schedule, your household members, living situation
    all aspects of puppyhood with your family veterinarian –       and the type of personality you would like your new dog                                                                                                                                  Puppies are given this test between six
    they are uniquely positioned to help,” says Dr. Jason Coe,     to have.                                                                                                                                                                                 and eight weeks of age, once their hear-
    one of the study’s authors.                                                                                                                                                                                                                             ing is fully developed. Testing puppies
                                                                                                                                                                                                                                                            for deafness is important because early
                                                                                                                                                                                                                                                            identification allows owners to provide
                                                                                                                                                                                                                                                            targeted training, improving comfort
                                                                                                                                                                                                                                                            and safety for their dog, and allows them
                                                                                                                                                                                                                                                            to be equipped with more information
                                                                                                                                                                                                                                                            about how to interact with and help
                                                                                                                                                                                                                                                            their dog navigate their world. Hearing
                                                                                                                                                                                                                                                            tests are also available for older pets that
                                                                                                                                                                                                                                                            may develop a loss of hearing as they
                                                                                                                                                                                                                                                            age. When deafness is not an inherited
                                                                                                                                                                                                                                                            or age related problem, loss of hearing
                                                                                                                                                                                                                                                            may also be an indicator of other health
                                                                                                                                                                                                                                                            issues, such as a brain tumour, infection
                                                                                                                                                                                                                                                            or trauma.

                                                                                                                                                                                                                                                            Dogs can be diagnosed with deafness in
                                                                                                                                                                                                                                                            both or just one of their ears. Dogs who
                                                                                                                                                                                                                                                            are deaf can live a normal life by using
                                                                                                                                                                                                                                                            their other senses, such as smell and
                                                                                                                                                                                                                                                            sight, which are heightened. Dogs with
                                                                                                                                                                                                                                                            hearing loss are best matched with an
                                                                                                                                      Nancy Warner’s seven English Setter puppies, shown here, visited the Neurology Service at the Ontario Veterinary      owner who is home more often and can
                                                                                                                                      College in February for brainstem auditory evoked response (BAER) testing, an evaluation of the auditory pathway as
                                                                                                                                      sound is translated from the eardrum to the brainstem.                                                                provide a fenced backyard and dedicated
                                                                                                                                                                                                                                                            time to training.
6                                                                                                                                                                                                                                                                                                    7
Starting your puppy off on the right paw - Smiling Blue Skies
For the Love
    of LULU
    It’s easy to see the love and affection Julia Clubb and Tony   and his team. Prior to surgery, Lulu had a CT scan that
    Soares have for their nine-year-old dog, Lulu.                 showed not only the enlarged anal sac, but 11 enlarged
                                                                   abdominal lymph nodes as well. The cancer had already
    Lulu and Tony start most days with a 10-kilometer run in       spread throughout Lulu’s body. An anal sac removal
    their Toronto neighbourhood. The active, apricot Standard      was performed followed by the removal of all abnormal
    Poodle enjoys swimming, visiting her local dog park and        lymph nodes. The goal of this surgery is to get rid of as
    spending time outdoors at their cottage. “There isn’t a        much cancer as possible by removing the diseased anal                                                                                                           “It truly is amazing how this technology can help pets,” says
    squirrel in our neighbourhood that is safe,” Julia laughs.     sac tumor and abnormal lymph nodes.                                                                                                                             Julia. “All of our friends at the dog park have heard about it
    “Lulu has a sweet personality and always makes us laugh.                                                                                                                                                                       from us because they knew what Lulu was going through.
    There is nothing better than when you find a tennis ball       Two weeks later, Lulu began chemotherapy to help                                                                                                                We are so thankful and have seen the benefits of minimally
    at the park that isn’t yours – that’s our Lulu.”               manage her disease, as anal sac cancer has a high chance                                                                                                        invasive surgery first hand.”
                                                                   of reoccurring.
    In June 2017 while visiting their family veterinarian, Dr.                                                                                                                                                                     The couple was so impressed with Lulu’s recovery that they
    Lindsay Paterson at Rosedale Moore Park Veterinary             “Dr. Singh was not only caring for Lulu, but he also cared                                                                                                      are holding an event at their home this spring to promote
    Clinic, a small lump was found during Lulu’s annual            for us and what we were going through,” Julia reflects.                                                                                                         the work of OVC Pet Trust and support advancing the clinical
    wellness exam. Lulu was immediately referred to the            “The fear of the unknown as a pet owner in these                                                                                                                research area of MIS at OVC.
    Ontario Veterinary College (OVC), where she was diag-          circumstances can be overwhelming. During a time when
    nosed with metastatic anal sac adenocarcinoma, a type          we needed support, he went above and beyond, commu-                                                                                                             It’s been a tough haul, but the fight isn’t over yet. Lulu will
    of cancer. “We were totally devastated when we received        nicating with us regularly. He helped alleviate our fears,                                                                                                      continue to return to OVC’s Animal Cancer Centre every
    the news,” says Julia.                                         kept us up-to-date and formed a plan about how we                          necessary as in the case of more traditional open surger-                            three months for monitoring, where her family meets with
                                                                   would proceed and navigate our dog’s diagnosis.”                           ies. In general, MIS is associated with less pain, a shorter                         Internal Medicine Veterinary Specialist Dr. Danielle Richard-
    Lulu’s diagnosis, anal sac cancer, is a highly-aggressive                                                                                 hospital stay and fewer complications in both humans and                             son to talk about Lulu’s health. Julia and Tony are apprecia-
    local cancer that can spread quickly through the lymph         At a follow-up visit in late August, a CT scan found that                  animals. While MIS is often preferred for these reasons, it                          tive Dr. Richardson has been a special part of Lulu’s medical
    node system. Lymph nodes are part of the body’s immune         Lulu had an enlarged lymph node in her chest. Singh was                    may not always be an option depending on the patient’s                               journey, helping to navigate their dog’s post-operative care
    system and when dogs are healthy, they help to fight           successfully able to use a minimally invasive surgical (MIS)               illness or disease. Lulu’s owners noticed a drastic difference                       to continue the battle against her cancer.
    infection and disease. When dogs are sick, the system can      technique to remove the lymph node with a procedure                        in her recovery after MIS compared to her earlier surgery in
    work like a freeway, allowing disease to move and spread       called thoracoscopy. Thoracoscopy involves several tiny                    June, which had been a traditional open procedure.                                   “It means everything to us that OVC helped our dog,” Julia
    quickly, to all parts of the body. Unfortunately, Julia and    incisions into the chest to insert a camera and surgical                                                                                                        and Tony both agree. “Lulu means the world to us. We are
    Tony learned this was the case with their sweet Lulu.          tools to remove a mass, or in this case a lymph node.                      “Lulu improved so much more quickly following the MIS                                so thankful OVC was there to support us during one of the
    Upon arrival at OVC, Dr. Tony Mutsaers evaluated Lulu          Minimally invasive surgery means just that – a surgery                     procedure in her chest. She came home the next day, and                              most devastating times in our life. It’s difficult to put into
    at the Mona Campbell Centre for Animal Cancer and              that is the minimal or causes the least amount of intru-                   you’d never know she’d had surgery. She was able to return                           words how grateful we are OVC was there when our family
    recommended surgical consultation with Dr. Ameet Singh         siveness to the body, because large incisions are not                      to her every day activities much sooner,” Tony remembers.                            needed it most.”

                                                                                                                                  In 2017, Dr. Ameet Singh was named as one of 15 American College of Veterinary Surgeons (ACVS) Founding Fellows in Minimally Invasive Surgery. Dr. Singh has obtained
                                                                                                                                  additional training and experience in minimally invasive surgery (MIS) beyond the ACVS surgery residency training and devotes a major portion of his professional effort to the
                                                                                                                                  prevention, diagnosis, treatment and rehabilitation of patients undergoing MIS therapies and to research in the field of MIS.
8                                                                                                                                                                                                                                                                                                                   9
Starting your puppy off on the right paw - Smiling Blue Skies
RESEARCH SPOTLIGHT

The TALE of                                                                                                                                                                 Is a Pet Rabbit a
                                                                                                                                                                            Good Fit for You?
Minimally Invasive Surgery                                                                                                                                                  Pet owners’ knowledge of pet care has been scientifically
     Advancing care for pet rabbits                                                                                                                                         shown to affect the human-animal relationship and the
                                                                                                                                                                            welfare of companion animals. Before welcoming a pet rabbit
                                                                                                                                                                            into your home, it is important to make an informed decision
     Rabbits are the third most owned pet in             Beaufrère, health trends indicate there can                                                                        and understand the demands of rabbit ownership and the
     North America, after dogs and cats. Rabbits         be serious risks if rabbits are left unspayed.                                                                     type of care they require over their lifetime.
     have become a popular pet for many rea-             “Cancer of the uterus can be a very common                                                                            • Rabbits require a lot of care. Their cages need to be
     sons. They have a friendly nature, they can         disease in female rabbits,” says Beaufrère.                                                                             cleaned daily, they need to be fed at least twice daily
     adapt easily to living in smaller spaces like       “If they are not spayed there is up to a 70                                                                             and they require exercise and mental stimulation.
     apartments or condominiums and, since               per cent chance they can develop this type
     most are indoor pets, they don’t necessarily        of cancer over their lifetime.”                                                                                       • Rabbits are most active in the morning and evening
     need to spend time outside of the home.                                                                                                                                     hours.
                                                         Since rabbits are much smaller than other                                                                             • Many rabbits do not like to be picked up. Rabbits have
     Avian and exotic care is a special interest         species, minimally invasive surgical options                                                                            delicate bones compared to their muscle mass. Owners
     within veterinary medicine. Veterinarians           could prove to have its benefits. “Rabbits                                                                              should practice careful handling to avoid bone fractures.
     who work in this area must understand               have a very different anatomy when                                                                                      If not held securely, rabbits can violently kick and break
     the anatomy and health needs of a wide              compared to dogs and cats. The goal of our                                                                              their back.
     range of animals, many of which are not             study is to determine if MIS spay procedures                                                                          • A pet rabbit is a long-term commitment. They have a life
     native to North America. From birds and             would be a better option for our rabbit                                                                                 span of approximately 9-10 years; some may live up to 12
     reptiles, such as turtles, lizards and snakes,      patients,” says Beaufrère.                                                                                              years of age.
     to companion mammals such as rabbits,
     ferrets and guinea pigs, avian and exotic           Beaufrère stresses the importance of size                                                                             • Rabbits are prey animals. Owners must be very cautious
     specialists at the Ontario Veterinary College       when performing surgery on smaller pets.
                                                                                                                                                                                 if they are considering introducing a rabbit into a new
     (OVC) provide diagnostic, emergency and             “An incision that would be considered tiny
                                                                                                                                                                                 home with other pets. If a dog or cat scratches or
     advanced care for all sorts of species.             in a much larger animal is actually a very
                                                                                                                                                                                 bites a rabbit, it can lead to serious trauma. Ask your
                                                                                                                                                                                 veterinarian for more information.
                                                         big incision for smaller animals, such as
     With rabbit ownership on the rise, they are         rabbits,” adding that the ability to provide
     now one of the most seen pets on the OVC            minimally-invasive options for these
     Avian and Exotics Service – making up 30            patients could decrease the size of surgical
     to 40 per cent of the services’ total patients.     incisions by 50 to 60 per cent. It is for this
     “Rabbits are very social animals. They              reason that Beaufrère and his team are
     generally enjoy interacting with people and         specifically looking at the use of miniature
     form close bonds with their owners,” says           MIS equipment that is currently used in
     Dr. Hugues Beaufrère, OVC’s Chief of Avian          surgery for young children.
     and Exotics Service.
                                                         “At the end of the day, we hope to gain
     Dr. Beaufrère, along with OVC Avian and             knowledge by determining the safest, most
     Exotics specialist-in-training Dr. Claudia          effective method for rabbit spay surgery,
     Kabakchiev and small animal surgeon Dr.             reduce patient health risks and provide the
     Ameet Singh, is currently investigating the         best evidence-based options for veteri-
     safety and benefits of minimally invasive           narians and the growing number of rabbit
     surgery (MIS) to spay rabbits. According to         owners out there.”

What is Minimally Invasive Surgery?
                                       Minimally invasive surgery (MIS) is common in human medi-
                                       cine, and more recently, in the veterinary world. MIS involves
                                       tiny incisions with scopes for doctors to see inside the body
                                       and remove organs, perform biopsies and other procedures.
                                       It is an alternative to traditional surgeries that involve making
                                       a large opening in the body; since the incision in MIS is very
                          Camera
                                       small, patients are usually able to recover faster and experi-
                                       ence less pain when compared to “open” procedures.
                                                                                                           three-week-old bunny patients’ first health check at ovc with registered Veterinary Technician, Sarah.
                                                                                                           Left to right: Burrito, pumpkin, russell, bandit, bunbun and pip.
10                                       MIS photo courtesy of Cancer Research UK / Wikimedia Commons.                                                                                                                                        11
Starting your puppy off on the right paw - Smiling Blue Skies
dogs in the office:
                                                                                                                     bryce and pivot are Part of ren’s head
                                                                                                                             office employee pet program.

         It wouldn’t come as that much of a surprise that      Locally, Ren’s works with humane societies            “Pets are our family members,” says Arsenault,
         you’d be greeted by a couple of friendly “woofs”      within the communities in which they operate.         who has three dogs and two cats of his own at
         when you walk into the head office of Ren’s Pets      They also strive to support organizations that        home. “That belief is at the core of our business.
         in Guelph. Life-size letters on the wall above        value the bond between pets and the people            We know our customers consider their pets to be
         reception welcome guests to headquarters:             that care for them. When they opened their            an important part of their family and only want
         “Passionate about pets and the people they            fifteenth store in 2017, Ren’s partnered with Don     the best for them.”
         own,” which not only serves as the company’s          Cherry to exclusively sell a line of beef liver dog
         corporate mission, but also embodies the way of       treats in honour of fallen Canadian soldier, Cor-     Arsenault believes OVC is the premier location for
         life for employees and customers alike.               poral Nathan Cirrillo, who was an avid pet lover      discovery and treatment for companion animals
                                                               and was killed in the line of duty at Parliament      in Canada and beyond. “If you are a pet owner,
         When President Scott Arsenault started with           Hill in 2014. All proceeds from the sale of the       you know the high level of care a pet will receive          Animals of all shapes and sizes are        The service is located deep within         dedicated to advanced clinical
         the company seven years ago, there were three         dog treats support the training of rescue dogs        when someone says they are taking them to the               referred to the Ontario Veterinary         the hospital and offers a variety of       education and research. Monica’s DVSc
         Ren’s stores. The premier pet retailer has grown                                                            University of Guelph (U of G),” Arsenault says.             College (OVC) every day for specialized    specialized medical imaging proce-         position is one of several special-
         to operate 16 stores across Ontario, with plans to                                                                                                                      care. Some are sent for advanced           dures including digital radiography        ist-in-training roles funded by OVC Pet
         open seven more this year and expand nationally                                                             “Even if your pet hasn’t been referred to OVC for           tests which can involve state-of-          (X-rays), ultrasound, fluoroscopy (real-   Trust. The intensive training program
                                                                                                                                                                                 the-art diagnostic imaging from            time X-ray), CT scan and magnetic          will equip her with the knowledge
         across Canada in the coming years.                                                                          advanced or emergency care directly, the U of
                                                                                                                                                                                 highly-trained veterinary health care      resonance imaging (MRI). On average        and experience she needs to become a
                                                                                                                     G will somehow have an influence on your pet’s              professionals.                             the team sees 40 patients per day,         board-certified veterinary radiologist.
d        “Everyone who works at Ren’s makes a difference                                                             life. Whether it be the advanced care for animals                                                      both large and small animals, and
         in the lives of pets – from accounting, to mar-                                                             that is available in their hospitals, treatment             The field of Diagnostic Imaging, some-     each day is different. Diagnostic imag-    Monica spends the majority of her
         keting, to the front lines. Each employee plays a                                                           options that may not be available today but                 times known as Radiology, involves         ing is the most visual of all medical      time performing ultrasound examina-
         role in the big picture of our business,” Arsenault                                                         will be tomorrow because of the innovative                  a series of different tests that take      specialties, and veterinary radiolo-       tions and interpreting X-ray, CT and
         says.                                                                                                       discoveries of their researchers, or the training           images of various parts of the body.       gists are specially trained to evaluate    MRI images, and using these images
                                                                                                                     and education provided to their graduates                   Essentially, it is the science that uses   and interpret images to diagnose           to deliver diagnoses and make recom-
r        A couple of years ago Ren’s head office adopted                                                             (the family veterinarians that work in our local            various medical imaging techniques         disease in all types of animals. Their     mendations on next steps in patient
         a pet policy, where employees are allowed to                                                                communities), your pet probably has been or will            to diagnose and sometimes also treat       skills and training allow them to often    care plans. Monica is also dedicated to
         bring their dog to work with them. While there        as post-traumatic stress disorder (PTSD) service      be positively affected by OVC during its lifetime,”         diseases within the body, from chronic     find a needle in a haystack, and their     her primary research project which is
         are guidelines, morale has increased and job          companions for military veterans and first            Arsenault says. “It may not be today; it may not            conditions like respiratory or kidney      expertise and knowledge is critical in     evaluating the presence and effective-
                                                                                                                                                                                 diseases to cancer.                        creating care plans for patients.          ness of radiation safety training for
         performance has remained intact and perhaps           responders in Canada.                                 be tomorrow. If you have a pet, they will most
                                                                                                                                                                                                                                                                       student veterinarians and veterinary
         even improved. “Everyone is so much happier.                                                                likely be touched by the work that’s being done             Early diagnosis of disease in pets         Our writer went behind-the-scenes          health providers in general practice.
         When you walk by purchasing and see Pivot the         Giving back to companion animal health and            at Guelph. How can you not support it?”                     saves lives. Without diagnosis, there      with Diagnostic Imaging resident           It is Monica’s hope that her work will
         Border Collie, you have to stop and smile and say     well-being is another important goal for the                                                                      can be no treatment and no potential       and specialist-in-training, Dr. Monica     lead to the development of new and
         hi,” Arsenault says.                                  company. This past August, Ren’s celebrated           Arsenault acknowledges $15,000 was a good                   cure. For this reason, OVC’s Diagnostic    Jensen, for a glimpse into the black       mandatory safety training guidelines
                                                               National Dog Day by raising funds at their store      start for their first year of corporate support. “We        Imaging (DI) Service is a critical hub     and white world of radiology.              for the use of X-rays in practice, as well
         When it comes to giving back, Ren’s focuses on        locations across Ontario for OVC Pet Trust, the       play in the land of great at Ren’s. Our goal is to          for all services within the OVC Health                                                as ensuring OVC is training student
         the pet owner community, confidently standing         company’s national charity of choice. The event       give up to $250,000 annually,” he smiles.                   Sciences Centre and an important           Monica is a senior resident in the         veterinarians to be leaders in radia-
         behind and passionately endorsing products            raised $15,000, funds that will go towards                                                                        referral resource for primary care         Doctor of Veterinary Science (DVSc)        tion safety in the workforce.
         and services aimed at improving healthy pet           advancing pet health through research, teaching       Visit your local Ren’s Pets store on this year’s National   veterinary hospitals across the prov-      program, a post-professional degree
                                                                                                                     Dog Day (August 26, 2018) to support OVC Pet Trust.         ince and beyond.
         lifestyles.                                           and care at the Ontario Veterinary College (OVC).                                                                                                                                                                            Continues on next page.
    12                                                                                                                                                                                                                                                                                                                13
Starting your puppy off on the right paw - Smiling Blue Skies
of JD’s throat,
                                                                                        esophagus and
                                                                                                                9:55 AM Monica is paged by a Reg-                                                                              science and art. It is about listening, observing,
                                                                                                                                                                                                                               seeing, interpreting, communicating and sharing
                                                                                                                                                                                                                                                                                         messenger; they’re the deliverers of both good and
                                                                                                                                                                                                                                                                                         bad news. The passion Monica has for her job is very
                                                                                                                istered Veterinary Technician (RVT) on her
                                                                                        stomach to try to                                                                                                                      information across many areas of expertise to help        obvious. “Most pet owners that visit OVC wouldn’t
                                                                                                                service. The team is ready for her to perform an
                                                                                        find a cause for JD’s                                                                                                                  our patients get the best care possible and on to the     know my name or who I am. This is still an adjust-
                                                                                                                ultrasound on a Newfoundland dog. In order
                                                                                        history of vomiting                                                                                                                    road to recovery.”                                        ment for me as I loved the relationships I developed
                                                                                                                to run the test with as little stress as possible
                                                                                        at home. The                                                                                                                                                                                     with people and their pets when I worked directly
                                                                                        process will involve
                                                                                                                for her patient, the dog is sedated before her
                                                                                                                arrival. General anesthesia is common for certain
                                                                                                                                                                                                                               11:26 AM Brain scans from a patient in MRI                with them in private practice,” Monica shares.
                                                                                        three stages: taking                                                                                                                   land into Monica’s queue as a horse patient named         “Instead, I look at and interpret images of almost
                                                                                                                advanced imaging procedures that may demand                                                                    Casper from the Large Animal Hospital is prepared
                                                                                        X-ray images while                                                                                                                                                                               every single patient that walks through the door
                                                                                                                more time and require patients to remain                                                                       for a sacraliliac (SI) joint injection which is used to
                                                                                        JD swallows liquid                                                                                                                                                                               and for that short amount of time, they become my
                                                                                                                perfectly still, such as CT and MRI. When Monica                                                               treat SI joint disease and pain. In horses this con-
                                                                                        barium, taking                                                                                                                                                                                   patient. Seeing these patients treated and overcome
                                                                                                                arrives the RVT has already started the test                                                                   dition quite literally means a pain in the rump. The
                                                                                        images after he                                                                                                                                                                                  their obstacles based on our imaging findings, the
                                                                                                                along with two DVM students who are on their                                                                   veterinarians on his care team hope this steroid ther-
                                                                                        eats canned wet                                                                                                                                                                                  hard work of other veterinarians working on their
                                                                                                                DI rotation. Monica takes over the procedure                                                                   apy will help reduce their patient’s pain and inflam-
                                                                                        food mixed with                                                                                                                                                                                  case and the commitment of their owners is one
                                                                                                                and receives a patient history from the RVT.                                                                   mation. Monica performs the ultrasound-guided
                                                                                        barium, and taking                                                                                                                                                                               of the most rewarding feelings I’ve experienced
                                                                                                                She probes the patient to take a closer look and                                                               procedure with Dr. Nykamp’s supervision.
                                                                                        images after he                                                                                                                                                                                  working in this field.”
                                                                                                                capture the images she will need to analyze.
                                                                                        eats liquid barium
                                                                                        mixed with kibble.
                                                                                                                10:24 AM Monica catches up on paper-                                                                           1:36 PM           Monica’s afternoon is full with
                                                                                        Barium sulfate is                                                                                                                      scheduled appointments. Six dogs are here for
     8:00 AM Monica’s day begins with                     an edible dye used for taking diagnostic images
                                                                                                                work between patients. She regularly references
                                                                                                                evidence-based academic papers and findings
                                                                                                                                                                                                                               ultrasounds this afternoon for various reasons,
     DI rounds every morning. While rounds in             in both human and animal health, and it works                                                                                                                        along with a guinea pig named Paddington who is
                                                                                                                during her report-writing. She downloads a            “I remember watching my uncle work with animals
     other specialties at OVC include checking in on      by coating the inside of the patient’s esophagus,                                                                                                                    experiencing diarrhea and stomach pain. A dog has
                                                                                                                paper about heartburn in veterinary patients and      and know he was making a difference in the lives of
     patients, it’s a bit different on the Diagnostic     stomach, or intestines. Since barium provides                                                                                                                        his spleen examined and Monica takes fine needle
                                                                                                                includes it in an email with some other follow-up     his patients who couldn’t speak for themselves, and I
     Imaging service. Monica, along with first-year       contrast, it allows these parts of the body to be                                                                                                                    samples for further testing. The cells she collects are
                                                                                                                information to the intern in charge of JD’s case.     was hooked,” she says. “I knew I wanted to make the
     resident Dr. Alexandra Beaulieu and board-certi-     seen more clearly on a CT scan or other X-ray                                                                                                                        placed on slides and sent to the University’s Animal
                                                                                                                A new ultrasound is underway for a dog with           same impact myself one day.”
     fied veterinary radiologist Dr. Stephanie Nykamp     examination.                                                                                                                                                         Health Laboratory for analysis.
                                                                                                                abdominal pain, vomiting and diarrhea. She
     gather in the “reading room” for the rounds of
     the day, with today’s focus being “retro rounds”.    9:29 AM Monica reports back to Dr.                    reviews the ultrasound with her students. “Our        11:15 AM Dr. Nykamp checks in with                       2:43 PM           While she is finishing up her
                                                          Nykamp with her diagnosis for JD: gastroesoph-        ultrasound today isn’t showing any reason that        her residents, discussing the day’s cases and            paperwork for a patient, the Large Animal Hospital
     The OVC Health Sciences Centre is a teaching
                                                          ageal reflux, or heartburn, which is common in        would indicate why our patient appears to be in       clarifying the medical language that should be           requests an emergency consult on a pig named
     hospital, and Dr. Nykamp is both a supervisor
                                                          both pets and people when the area between            pain,” she says, curiously. “We can only rely on      used in report-writing. She reminds her team that        Oliver. The service veterinarian suspects rupture of
     and an educator; she oversees, instructs and
                                                          the esophagus and stomach doesn’t close or            what the images tell us. It’s frustrating when we     continually asking questions is key and that while       a component of the urinary tract and they look to
     mentors the entire medical team on her service.
                                                          stay closed properly, allowing stomach contents       can’t find a clear answer.” Some diseases can’t       diagnostic imaging helps with more precise and           Monica’s expertise for answers. Monica performs an
     Monica pulls up a computed tomography (CT)
                                                                                                                be detected with imaging techniques and are           faster diagnosis it is not the same as determining the   ultrasound on Oliver. Much of her job involves logic
     scan of a cat with a thyroid tumour at her
     reading station. Dr. Nykamp and Alexandra pull
                                                                                                                only visible at the microscopic level. But Monica’s
                                                                                                                findings are an important piece of the puzzle and
                                                                                                                                                                      severity of the diseases that are being interpreted.     and an understanding of the physiological processes       5:06 PM After Monica sees her last patient
     their chairs over to join Monica. “Retro rounds is                                                                                                                                                                        underlying what is happening in the body. She             of the day, rounds with student veterinarians begin,
                                                                                                                may still help the patient’s veterinarian when        “Diagnostic imaging is a process of discovery; it lets   uses the images she captures to tell a story. Monica      which are led by Monica and Dr. Nykamp. One
     our dedicated time to review cases together as
                                                                                                                they review bloodwork and history to arrive at a      us see what is really happening inside the body and      consults with Dr. Nykamp and Oliver’s veterinarian to     student presents two cases from the day and sum-
     a team,” Monica explains. The first hour of the
                                                                                                                diagnosis.                                            findings often direct the care plan rather than solve    recommend next steps.                                     marizes case findings and patient history. Monica
     day is spent examining historical patient scans,
                                                                                                                                                                      the health issue,” Dr. Nykamp says. “It reminds us
     discussing diagnoses and disease processes. Dr.
     Nykamp prompts her residents with questions
                                                                                                                11:00 AM Monica isn’t at her station                  that veterinary medicine is truly a collaborative        3:53 PM           The day is jam-packed with
                                                                                                                                                                                                                                                                                         asks questions and helps fill in the gaps during the
                                                                                                                                                                                                                                                                                         student’s presentation. Dr. Nykamp reviews the
                                                                                                                for more than five to 10 minutes at a time before
     such as “What evidence supports your state-                                                                                                                                                                               organized chaos. There are three more planned             schedule for the next day with her team, revealing
                                                                                                                she is on the move throughout the hospital
     ment? What led you to that diagnosis? What’s                                                                                                                                                                              ultrasound patients booked this afternoon. Monica         they’ll have an alpaca in for a CT scan.
                                                                                                                again. Radiology in veterinary medicine is more
     next for our patient?” to encourage discussion                                                                                                                                                                            carefully obtains images of each organ in the abdo-
     and debate. In a teaching environment this time
                                                                                                                than just sitting in a dark room reading images;
                                                                                                                Monica is constantly out and about, conducting
                                                                                                                                                                                                                               men and records the measurements in her report.           5:30 PM Rounds are over and Monica is
     is very valuable. It focuses on building interpre-                                                                                                                                                                                                                                  done for the day. “Some shifts are longer than
     tive skills and reinforces the importance of life-
                                                                                                                diagnostics in pets, consulting with her team
                                                                                                                and delivering her reports back to each service
                                                                                                                                                                                                                               4:03 PM Monica is responsible for providing               others, depending on our case load and the number
     long learning within the veterinary profession.                                                                                                                                                                           mentorship to her junior resident. Alexandra asks         of emergencies that present over the course of
                                                                                                                so they can then discuss treatment options with                                                                Monica a question about a bearded dragon patient’s        the day,” she says. The OVC Health Sciences Centre
     Critical evalution and follow-through allows
                                                          to move into the esophagus. JD also has an            pet owners. With every passing minute, she has                                                                 anatomy while she examines his CT scan. Collabo-          is open 24/7. Monica isn’t on call tonight, but
     the team to ensure that they are practicing the
                                                          esophageal motility disorder, a condition where       to stay on her toes and at the top of her game.                                                                ration happens at all levels of learning and practice     tomorrow it will all begin again. “I love the diversity
     highest quality of veterinary medicine by using
                                                          fluid and food don’t move down the esophagus          Working well under pressure and attention to                                                                   within veterinary medicine.                               of the imaging options we can offer at OVC and the
     each and every case as a learning opportunity.
                                                          properly. Her findings are sent to the intern on      detail are definite requirements of the job.                                                                                                                             wide range of animals I get to work with. It’s not
     9:06 AM Monica’s first patient of the                the Internal Medicine service JD arrived on to        It is clear Monica is a pet lover; she has
                                                                                                                wanted to be a veterinarian since the age
                                                                                                                                                                                                                               4:24 PM Members of the surgical team enter                every field in medicine that you can go from treating
     day arrives, a Pug named JD, who is here for a       share with his owner and to develop next steps                                                                                                                       into the reading room to ask Monica and her fellow        a horse to a guinea pig to a kitten in the same day,”
                                                          in his care.                                          of five. Monica’s uncle is a veterinarian and                                                                  resident Alexandra about one of their patient’s CT        she says. “I feel so fortunate to contribute to truly
     real-time X-ray procedure called an esophagram.
                                                                                                                she used to visit his clinic as a child.                                                                       scans. It’s Monica’s job to provide insight, guidance     making a difference for people and their pets.”
     During the procedure Monica will take images
14                                                                                                                                                                                                                             and answers to move forward. The DI team is the                                                                 15
Starting your puppy off on the right paw - Smiling Blue Skies
HEAL, BOY
                                                                                                                                  By February, a biopsy came back cancer:                have relevant models that can be stud-               pathogens that might trigger mutant
                                                                                                                                  aggressive multicentric lymphoma.                      ied so much cheaper than human trials.”              cells that morph into cancer. Dogs are
                                                                                                                                  For Bosco’s owners, the grim diagnosis                 There’s also a risk that any adverse                 genetically diverse, just like humans,
                                                                                                                                  was devastating. “He couldn’t possibly                 event that might be species-specific                 and have intact immune systems. Com-
                                                                                                                                  leave us, because we had fallen so                     — “on rare occasions,” he says, “cats                panion animals also develop tumours
                                                                                                                                  deeply in love with him,” Lynda remem-                 don’t behave like people” — would                    naturally and spontaneously, the same

       how your pet may save your life one day                                                                                    bers thinking.                                         slow down progress on human drug
                                                                                                                                                                                         development.
                                                                                                                                                                                                                                              way we do. Some shared tumours –
                                                                                                                                                                                                                                              osteosarcoma, or bone cancers, mucosal
                                                                                                                                  On their vet’s advice, they turned to                                                                       melanoma, non-Hodgkin’s lymphoma,
                     by Sharon Kirkey, National Post                                                                              the Ontario Veterinary College’s Mona                  So labs continue to use mice — not                   bladder cancer – can be so functionally
                                                                                                                                  Campbell Centre for Animal Cancer.                     sweet, mixed breed family dogs — for                 identical it’s hard to know “dog” from
                                                                                                                                  Bosco was immediately scheduled for                    research. Withrow says there’s still a role          “human” when looking at a biopsy.
                                                                                                                                  25 rounds of chemo at the facility, part               for rodent research. But, will our sensi-
                                                                                                                                  of the University of Guelph. The family                tivities to household pets hold us back              Given the leap between mice and
                                                                                                                                  also agreed to enroll their mixed-breed                from helping them, and ourselves?                    humans, the thinking now is, “maybe
                                                                                                                                  rescue in several clinical trials, including                                                                there’s a better stepping stone,” says
                                                                                                                                  one exploring whether a special molec-                 The thing is, when researchers suc-                  Brian Lichty, of McMaster University’s
                                                                                                                                  ular test can predict early enough how                 ceeded in mapping the first full genome              Immunology Research Centre, who is
                                                                                                                                  well dogs with advanced lymphoma are                   of a dog in 2005 – Tasha, a female Boxer             collaborating with Ontario Veterinary
                                                                                                                                  responding to their chemo, so they can                 – they discovered humans share more                  College (OVC) researchers testing a
                                                                                                                                  be switched to a more effective drug if                of their ancestral DNA with dogs than                breast cancer vaccine in cats.
                                                                                                                                  needed.                                                with mice.
                                                                                                                                                                                                                                              The cardiovascular systems of dogs
                                                                                                                                  All this might sound extreme. The                      In fact, studies suggest that 85 per cent            and people are also remarkably
                                                                                                                                  price tag for canine cancer treatments                 of drugs that appear promising when                  similar, veterinarians say. Canine dilated
                                                                                                                                  — surgery, chemotherapy, radiation                     tested on the lowly lab rodent fail                  cardiomyopathy, a deadly disease that
                                                                                                                                  and potentially another surgery if the                 spectacularly when moved into humans.                causes the heart to weaken, dilate and
                                                                                                                                  cancer rebounds — can run $10,000 to                   Of those that make it to Phase III — the             swell like a balloon near bursting can
                                                                                                                                  $20,000. But Bosco’s treatment could                   final and priciest pre-licensing phase               lead to congestive heart failure. DCM is
                                                                                                                                  save not only his life, it may save yours.             — only half are ever approved. Cancer                the second most common form of heart
                                                                                                                                  Lymphoma in dogs is strikingly similar to              drugs are the ones most likely to flop.              disease in dogs – and the third most
                                                                                                                                  non-Hodgkin’s lymphoma in people; the                                                                       common in humans.
                                                                                                                                  results of Bosco’s clinical trial could lead           “Crucial genetic, molecular, immuno-
                                                                                                                                  to better therapies for cancer in humans.              logic and cellular differences between               Yet dogs age and die five to eight times
                                                                                                                                                                                         humans and mice prevent animal                       faster than humans, meaning the out-
                                                                                                                                  It’s just one of the diseases our pets may             models from serving as effective means               comes to studies testing new therapies
                                                                                                                                  help us treat. Vets are collaborating with             to seek for a cancer cure,” McMaster                 can be known that much sooner, and at
                                                                                                                                  researchers in human medicine to study                 University researchers wrote in 2014 in              far less cost.
                                                                                                                                  the genetics of a fatal heart disorder                 the American Journal of Translational
                                                                                                                                  shared by dogs and humans. They’re                     Medicine about the limits of animal                  All this may give some animal lovers
                                                                                                                                  working on epilepsy, and stem cell                     models “to mimic the extremely com-                  pause. “We understand why people
                                                                                                                                  therapy for spinal cord injuries.
                                               GUELPH, ON – There are none of the usual padded chairs and IV poles in the
                                               chemo room, just black gym mats on the floor and doggy treats at the ready.        “To me, it’s one medicine. It always
                                                                                                                                  has been,” writes veterinarian
                                               Eight-year-old Bosco is lying on his side, a catheter inserted into a hind leg.    Stephen Withrow on the website
                                                                                                                                  for the Flint Animal Cancer Center,
                                               His handlers, wearing protective masks and gowns, are on the floor with
                                                                                                                                  one of the world’s largest, which
     bosco receives                            him. One gently holds him down while the other checks to make sure the             he founded at Colorado State
     chemotherapy                              catheter is well inside the vein, so that the toxic chemo doesn’t spill into the   University. “One medicine. One cancer.                 plex process of human carcinogenesis,                may have this visceral and immediate
     at the Ontario                            surrounding tissue. “I’m in,” she says, then injects a syringe filled with the     One cure.”                                             physiology and progression.” Dogs and                reaction (to comparative medicine),”
     veterinary College.
                                               cancer drug doxorubicin. Bosco’s owners, Alex Magditsch and Lynda McCa-                                                                   humans, on the other hand, co-evolved.               says Dr. Alka Chanda, chief of laboratory
                                               rthy, first noticed a fatty lump on the dog’s left side at Christmas, and soon     But selling this to funding agencies and               We live in the same homes, not sterile               case management for PETA. In June,
                                                                                                                                  industry has been difficult, he says,                  cages, we breathe the same air and are               PETA supporters, wearing cat masks and
                                               after that, another small mass on his lower jaw. Their vet then discovered         “convincing big drug companies that we                 exposed to the same pollutants and                   crammed into cages, protested outside
                                               enlarged lymph nodes in his groin and neck.                                                                                                                                                                   Continues on next page. 17
16                                                                                                                                 Material republished with the express permission of: National Post, a division of Postmedia Network Inc.
Starting your puppy off on the right paw - Smiling Blue Skies
the New Jersey headquarters of three drug companies                                                  the second, James orders “happy juice,”                human child neurology at Sick Kids.                 ventricle, to become dilated and baggy. The
     that do business with a contract testing lab PETA has                                                a quick-acting, but also quick-reversing               Now she’s giving back. Working with the             heart muscle becomes weak and flabby and
     accused of violating animal cruelty laws.                                                            sedative. “She’s conscious,” James says, as            mobile backpack on Rhodesian ridgebacks,            struggles to pump blood around the body.
                                                                                                          the team resumes attaching the electrodes              James and an international team from Can-           In dogs, like people, it causes coughing and
     But while her organization is categorically opposed to                                               to Vallie’s scalp, cheekbones and the base of          ada, Germany and Finland have discovered            difficulty breathing from fluid retention.
     experimenting on dogs and cats in labs, these animals                                                her ears. “She just doesn’t care.”                     a new gene mutation in dogs that may
     are not being used as “test tubes with tails.”                                                                                                              help better diagnose and treat myoclonic            Recently, O’Sullivan collaborated with
                                                                                                          These electrodes will feed brain wave data             epilepsy, one of the most common forms of           researchers at the University of Washington,
     In the past, Withrow said in an interview with the                                                   wirelessly to a camera and laptop. James               epilepsy in children and adults. The disease        providing heart muscle samples from dogs
     Post, if a dog had cancer the most a vet could offer                                                 has created an EEG backpack worn by the                causes rapid, jerk-like movements of the            that have died of DCM. The Washington
     was cortisone, palliative care of some kind, and a one                                               dogs, modified from those worn by children,            face, limbs or muscles, like the sudden             team has identified a molecule involved in
     or two month shot at survival.                                                                       that allows the veterinary neurologist and             spasms that jolt us awake at night.                 muscle contraction. In heart cells from dogs
                                                                                                          professor in the OVC’s clinical studies depart-                                                            with DCM, it restored normal function. The
     “The increase in the pet animal-human bond raised                                                    ment to monitor a dog’s epilepsy while it is                                                               same molecule improved muscle function in
     pets almost to the level of children,” however,                                                      moving, even chasing a ball across a field,                                                                human cells.
     Withrow says. People wanted — and those who had                                                      instead of trying to diagnose epilepsy with
     the wherewithal to pay hefty sums for it — whatever                                                  the dog heavily sedated or under anesthesia                                                                For all this progress, though, it’s compar-
     it took to keep their pets alive. “And so we raised the                                              – which can abolish the very behaviours, the                                                               ative oncology that holds out the most
     bar.”                                                                                                twitches or seizures, she’s trying to catch.                                                               hope. Despite hundreds of billions of dollars
                                                                                                                                                                                                                     of research worldwide, cancer still ranks
     Today, he says, “when I do these major surgeries —                                                   Epilepsy is five times more common in dogs                                                                 among humanity’s most lethal killers.
     brain cancer, lung removal — I need critical care                                                    than in people and affects many types of
     for these patients to survive, so chest drains and                                                   breeds. The classic seizure for a dog is a                                                                 “These people who are looking for break-
     pain management, antibiotics, blood transfusion,                                                     generalized tonic clonic seizure. But dogs,                                                                throughs aren’t interested in whether the
     anesthesia. All the supportive stuff came along at the                                               like humans, also suffer absence seizures,                                                                 breakthrough comes from a dog or a zebra
     same time.”                                                                                          where they blank out briefly, or partial                                                                   fish,” Dr. Larry Glickman, professor emeritus
                                                                                                          seizures, “where you might have a little                                                                   at Purdue University said in a PBS documen-
     Dr. Len Lichtenfeld, deputy chief medical officer for                                                twitch, similar to the twitch you might get in                                                             tary on comparative oncology released last
     the American Cancer Society, says dogs with cancer                                                   an eyelid when you get tired and stressed,”                                                                year. “Just give us something we can work
     are treated as compassionately, maybe “sometimes                                                     James explains. It can be difficult to                                                                     with that will help speed up the process of
     even nicer” than people. “Nobody is taking a dog and                                                 distinguish these seizures — like the Boxer                                                                drug development, which is so long and
     putting him in a kennel in a room somewhere, never                                                   James once treated who would shake his                                                                     expensive.”
     to be seen again, and experimenting on them,” he                                                     head vigorously from side to side — from a
     says. “These are pets that are getting genuine care.”                                                behavioural issue, like an obsessive-compul-                                                               The OVC in Guelph is among the leaders in
                                                                                                          sive disorder.                                         Dr. Lynne O’Sullivan is also part of critical       animal-to-human medicine and the only
     His own dog, an 11-year-old golden retriever, died                                                                                                          discoveries in “translational” medicine             international member of a U.S. National
     of cancer last year, only weeks before he spoke at                                                   Working with her predecessor, Dr. Roberto              bridging humans and man’s best friend.              Cancer Institute consortium of comparative
     a U.S. National Academy of Medicine workshop on                                                      Poma, James decided to see whether they                The day we visit, the veterinary cardiologist       oncology trials. The Mona Campbell Cancer
     comparative oncology.                                                                                could record animals awake. “And we did                is performing an ECG on Maddie, a three-            Centre for Animal Cancer, which opened its
                                                                                                          that with a little Chihuahua who wore the              year old golden retriever and service dog           doors five years ago this month, is where
     “Has she been out to pee? I sound like such a mom.”                                                  cables when he was confined to a baby crib.”           for people with anxiety and panic attacks.          most clinical trials take place. There are
                                                                                                                                                                 Maddie has had a heart murmur since                 vets, pain specialists, anesthesiologists,
     Dr. Fiona James bends down to stroke Vallie, a                                                       His nose twitches turned out to be absence             puppyhood. O’Sullivan is checking for leaky         technicians, interns; a human-sized linear
     “Shorkie,” or Shih Tzu-Yorkie mix. Vallie has been                                                   seizures, the first time such seizures were            valves, turbulent blood flow or congenital          accelerator, chemo and oncology wards, and
     having seizure-like episodes for more than a year. She                                               recorded in a dog. After their paper was               disease. Maddie is panting heavily, a sign          a tumour tissue bank with 18,000 samples.
     sometimes goes limp, like a noodle, other times rigid                                                published, in 2010, James wondered,                    she’s nervous.
     and dazed. “You can call her name, but you can tell                                                  “Maybe we can go one step further. Maybe                                                                   The college offers advanced cancer surgery
     she’s not with it,” her owner, Cheryl Parker, says.                                                  we can cut the cable.”                                 “You can relax Maddie, you don’t have to            — among other feats, Dr. Michelle Oblak
                                                                                                                                                                 work right now,” O’Sullivan says softly in the      is removing tumours burrowed deep into
     Today, Vallie is lying on a blanket, James, her residents                                            She looked to the Hospital for Sick Children           darkened room as she moves the transducer           the brain cavity and rebuilding skulls with
     and students huddled in a circle around her, their                                                   in Toronto, working with researchers in                around the dog’s chest.                             titanium mesh instead of hoping muscle
     heads nearly touching. “There’s no personal space in                                                 pediatric epileptology. She got a grant,                                                                   and skin grows a flap over the missing scalp.
     neuro,” James quips as she inserts the first of 15 elec-                                             and started recording brain activity in dogs           O’Sullivan is an expert on dilated cardiomy-        Vets are also testing treatments for the
     trode needles into Vallie’s scalp, just beneath the skin.                                            suspected of having epilepsy. “They taught             opathy, or DCM, a disease that causes the           same bone cancer that killed Terry Fox, and
                                                                           two-year-old baby is carried   me a lot,” James says of her collaborators in          heart’s main pumping chamber, the left              immune therapy for melanoma.
     When the dog flinches with the first poke, then             in for her radiation treatment at OVC.
18                                                                                                                                                                                                                                     Continues on next page. 19
                                                                                                          Material republished with the express permission of: National Post, a division of Postmedia Network Inc.
You can also read