Specially Tailored support for a range of feeding issues - Practical guidance INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY - SMA HCP
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INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY BREASTFEEDING IS BEST FOR BABIES SCIENCE INSPIRED BY NATURE Specially Tailored support for a range of feeding issues Practical guidance
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY START HERE Is the baby full term? YES NO Is there a family history of allergy? Is the preterm baby receiving breast milk exclusively? YES NO YES NO PAGE 32 Does the baby have special nutritional needs? SMA H.A.® NO YES Infant Milk From birth SMA® SMA SMA SMA Breast Milk Gold Prem® 1 Gold Prem® 2 Gold Prem® 2 Fortifier Low Birthweight Post Discharge Post Discharge From birth Formula Formula Formula In hospital From birth 90 ml in hospital, For use at home In hospital 200 ml for use Prescribable at home (UK only) SMA® ADVANCED SMA® PRO Range SMA® Organic Range Prescribable LITTLE STEPS® Range Range First, Follow-on First, Follow-on & First, Follow-on & (UK only) First, Follow-on & & Growing Up Milks Growing Up Milks Growing Up Milks Growing Up Milks From birth, 6 months From birth, 6 months & From birth, 6 months & & 12 months 12 months 12 months From birth, 6 months & 12 months FOR MEDICALLY DIAGNOSED SPECIAL NUTRITIONAL NEEDS For babies with For babies with For babies For cows’ milk high energy significant intolerant to intolerant For babies with For hungrier needs reflux lactose/sucrose babies mild digestive babies discomfort PAGE 24 PAGE 28 PAGE 14 PAGE 20 SMA SMA® SMA LF® SMA® Wysoy® High Energy ® Anti-Reflux Lactose Free Soya Infant SMA ® SMA Extra ® From birth From birth From birth Formula Comfort Hungry Prescribable Prescribable Prescribable From birth Easy to Digest Infant Milk (UK & ROI) (UK only) (UK & ROI) Prescribable Infant Milk From birth (UK & ROI) From birth This chart is intended for bottle-fed babies, as a guide only and is not a diagnostic tool. 2 | SMA® Specials Range SMA® Specials Range | 3
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY The aim of this booklet is to describe Contents some of the common feeding issues Feeding issues and protein intake experienced by infants, and to help Understanding feeding issues.......................................................................... Importance of partially hydrolysed protein........................................................ 6 8 you reassure parents by offering Role of whey dominance................................................................................. 9 practical guidance. Reflux and regurgitation What is reflux and regurgitation?..................................................................... 10 Starch thickener + NICE guidelines.................................................................. 12 SMA® Anti-Reflux........................................................................................... 14 The advice contained within this booklet Comparison chart.......................................................................................... Preparation: instructions and comparison.......................................................... 15 16 is based upon the latest guidance from Mild digestive discomfort NICE and the Department of Health, Signs and symptoms....................................................................................... Diagnosis criteria........................................................................................... 18 19 where appropriate. SMA® Comfort Easy to Digest Infant Milk.......................................................... Comparison chart.......................................................................................... 20 21 Lactose intolerance What is lactose intolerance?........................................................................... 22 Types of lactose intolerance............................................................................ 23 SMA LF ® Lactose Free Infant Milk..................................................................... 24 Comparison chart.......................................................................................... 25 Cows’ milk allergy or intolerance Allergy vs intolerance?................................................................................... 26 Soya as a protein alternative........................................................................... 27 SMA® Wysoy® Soya Infant Formula.................................................................. 28 Allergy in infants Family history................................................................................................ 30 Supporting infants at risk of allergy.................................................................. 31 SMA H.A.® Infant Milk.................................................................................... 32 NICE: National Institute for Health and Care Excellence. What do the guidelines say?........................................................................... 33 4 | SMA® Specials Range SMA® Specials Range | 5
Feeding Issues BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY Feeding issues are a common Infant feeding issues are very common part of life for young infants1 This is due to a baby’s digestive system still being immature when born. Research shows that Functional gastrointestinal disorders (FGIDs) occur in up to 55% of all infants in the first 6 months of life.1 • FGIDs include a number of symptoms that affect the gastrointestinal tract in otherwise healthy infants3 INFANTS WHO HAVE FEEDING ISSUES • These symptoms are often frequent, age dependent, and related to the ongoing physiological development of the gut that occurs naturally after birth • Although they usually resolve as the infant matures, they can cause considerable distress and anxiety for the parents as well as the infant • As well as FGIDs, feeding issues also encompass lactose OVER HALF intolerance and cows’ milk protein allergy (CMPA), both of which have a defined organic cause THE MOST COMMON FGIDs ARE:2 • The prevalence of lactose intolerance varies according to 30% REFLUX & REGURGITATION cause and ethnicity.4 CMPA affects between 1.8%-7.5% of 20% COLIC infants in the first year of life.5 15% CONSTIPATION 6 | SMA® Specials Range SMA® Specials Range | 7
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY What is partially hydrolysed protein Partially hydrolysed, 100% whey and why is it important? protein encourages easy digestion Infants who have a FGID may benefit from partially hydrolysed protein in a formula. Breast milk contains partially hydrolysed proteins for easier digestion and absorption.7 Partially hydrolysed formulas have been shown to accelerate Partially hydrolysed means the protein is broken up into smaller pieces that are gastric emptying, making the formula easy for infants to digest.8 easier for the infant to digest. 40 39%* % remaining in stomach Plasmin 35 30 Big protein molecule Hydrolysis Small, more easily digested peptides 25 26% • Breast milk contains enzymes that hydrolyse proteins6 • Gastrointestinal symptoms such as constipation, fussiness, colic or spitting 20 Breast Milk 18% up are very common at an early age1 16% 100% whey, partially hydrolysed formula 15 • Some trials have demonstrated the efficacy of partially hydrolysed formula Intact whey-predominant formula in the community when CMPA was not considered to be the cause Intact casein-predominant formula 0 of the infant’s colic symptom2 Type of milk Partially hydrolysed formula may offer some advantage over After 120 minutes only 16% of 100% whey, partially hydrolysed formula intact protein in the dietary management of common functional remains in the stomach compared with 26% of intact whey-predominant formula gastrointestinal symptoms.2 and 39% of intact casein-predominant formula.8 Both the UK and Ireland Department of Health recognise that whey protein is easier to digest.9,10 FGID: Functional gastrointestinal disorder. * p
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY What is infant reflux and regurgitation? The importance of whey protein Gastro-oesophageal reflux (GOR) is an involuntary passage of gastric contents from the stomach into the oesophagus. Reflux is a normal physiological process for infants with feeding issues in otherwise healthy infants and is a common FGID in an infant’s first year.11 Breast milk is whey-dominant during the first 6 months of life.7 regurgitation Reflux and • When reflux is high enough to be seen, it is known as regurgitation2,3 WHEY-BASED INFANT FORMULAS: • Regurgitation or reflux occur daily in about 50% of infants under 3 months of age2 • Are more easily digested than those which are casein-based7 • This is primarily due to the functional immaturity • Contain an adequate supply of essential amino acids of the stomach inlet11 and higher protein quality, closer to that of breast milk12 In some cases, reflux may lead to complications and/or troublesome symptoms, which require further medical investigation and treatment – this is when gastro- oesophageal reflux disease (GORD) occurs.2,11 Rate of gastric emptying after 120 minutes, according to the type of milk8 40 39%* Lower Oesophagus % remaining in stomach 35 oesophageal spincter (valve) 30 Duodenum 25 Stomach 20 Pyloric 16% 15 spincter (valve) 100% whey, partially hydrolysed formula 0 Intact casein-predominant formula Type of milk FGID: Functional gastrointestinal disorder. * p
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY The effect of a starch thickener What the NICE guidelines say on symptoms of reflux In 2015, NICE recommended the following measures for managing formula-fed infants with frequent regurgitation associated with marked distress:11 Starch thickener reduces the frequency of regurgitation in infants.13 • Offer parental reassurance • Starch is an appropriate thickener for infants with reflux and regurgitation, as it is digestible by the infant • Review feeding history, suggest smaller, more frequent feeds (while maintaining appropriate daily milk volume intakes) • Starch-thickened formulas have shown efficacy in reducing the number of daily regurgitation episodes13 • Trial of a thickened formula If a thickened formula does not work, stop the thickened formula and offer alginate therapy for a trial period of 1–2 weeks. NICE Guideline on gastro-oesophageal reflux11 • Regurgitation of foods is a normal and common occurrence in infants • Does not usually require investigation • Reassure and advise parents and carers • Look out for ‘red flags’ that may indicate a need to refer, e.g. blood in stool, fever • In formula-fed infants with frequent regurgitation associated with marked distress, use a stepped-care approach: – Review feeding history –R educe food volumes only if excessive for the infant’s weight – T rial of smaller, more frequent feeds (while maintaining appropriate total daily amount of milk) – T rial of thickened formula – If above is unsuccessful, stop the thickened formula and offer alginate therapy for a trial period of 1–2 weeks NICE: National Institute for Health and Care Excellence. 12 | SMA® Specials Range SMA® Specials Range | 13
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA® Anti-Reflux How does SMA® Anti-Reflux compare? SMA® Aptamil Cow & Gate HiPP Enfamil A.R. REDUCES FREQUENCY Anti-Reflux14 Anti-Reflux 15 Anti-Reflux16 Anti-Reflux 17 (‘Anti-Reflux’)18 OF REGURGITATION13 Starch-thickened formulas Whey:casein 100:0 40:60 40:60 60:40 NS have shown efficacy in reducing the number Partially Type of protein Intact Intact Intact Intact of daily regurgitation hydrolysed episodes13 Protein content 1.3 1.3 1.3 1.4 1.72 (g/100 ml) Carob bean THICKENED FORMULA Type of thickener Potato starch Carob bean gum Carob bean gum Rice starch gum 2015 NICE guidelines recommend trial of a Vegetarian thickened formula in formula-fed infants with Halal GOR11 SPECIALLY TAILORED Unique combination of easily digestible starch and 100% whey, partially hydrolysed protein, to help manage reflux and regurgitation13-14. GOR: Gastro-oesophageal reflux. NICE: National Institute for Health and Care Excellence. NS: Not stated. 14 | SMA® Specials Range SMA® Specials Range | 15
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA® Anti-Reflux is easy to prepare Comparison of AR formulas* 1 Ptheulllid.theLiftsafetythe seal SMA® Aptamil Cow & Gate HiPP and open the lid. The scoop is provided under Anti-Reflux14 Anti-Reflux15 Anti-Reflux16 Anti-Reflux17 tab, pull on the foil seal, carefully and safely Step 1 Wash hands and sterilise all utensils according to the manufacturer’s instructions. remove the seal and dispose of it. Boil 1 litre of freshly run water. Do not use artificially softened or repeatedly boiled water. Allow to cool for no more Leave kettle to cool for Measure the required amount Leave to cool for no longer Step 2 than 30 minutes. no longer than 45 mins. of boiled water into a large than 30 minutes. 2 Wtoashmanufacturer’s Measure the required amount sterilised bottle. Seal bottle hands well. Wash and sterilise all utensils according of water into a sterilised and allow to cool for bottle. Be careful of scalding. 45 minutes. instructions. Place the sterilised teat Using the scoop provided Using the scoop provided, Measure the required amount and cap on the bottle. Cool level off the powder with the level the powder with the of water into a sterilised bottle, bottle under cold running built in leveller. Do not press/ built-in leveller. Do not following the feeding guide water or in a bowl or jug of heap the powder. press/heap the powder. on the pack. Using the scoop 3 BMeasure cold water until lukewarm, provided, add the correct oil 1 litre of tap water. Allow to cool for no more than 30 minutes. Step 3 do not immerse the teat. number of scoops of powder – one level scoop of powder the required amount of water (see feeding guide) into a for each fluid ounce of water (approx. 30 ml). Level off sterilised bottle, carefully – the water is hot. Do not use artificially the powder with the back of softened or repeatedly boiled water. a clean dry knife, but don’t press the powder down into the scoop. 4 Pcoldlacerunning Using only the scoop Add one scoop per Add one scoop to every Place the sterilised teat and the sterilised teat and cap on the bottle. Cool bottle under provided, add the correct 30ml (1 fl oz) of boiled and 30ml (1 fl oz) of boiled cap on the bottle and shake number of scoops of powder cooled water. Add the correct cooled water. Add the correct well until all the powder water or in a bowl or jug of cold water until (see feeding guide), levelling number of scoops to the water. number of scoops to the water. has dissolved (approx. off each scoop with the back Adding too many or too few Adding too many or too few 15 seconds). lukewarm, do not immerse the teat. of a clean, dry knife. Store scoops can be harmful. scoops can be harmful. the scoop in suspension inside Place the sterilised teat and Replace seal on bottle and the can and replace lid. 5 Uofsingpowder cap on the bottle. roll the bottle upright between Step 4 only the scoop provided, add the correct number of scoops Hold the bottle horizontally the palms of hands – roll it strongly for 5 seconds. and shake from left to right (see feeding guide), levelling off each scoop with the for 10 seconds, then hold it The time between adding the scoops and rolling the bottle back of a clean, dry knife. Store the scoop in suspension inside vertically and shake from top to bottom for 10 seconds. The should be as short as possible. the can and replace lid. time between adding the scoops and shaking the bottle should be as short as possible. 6 Sbyhakeshaking bottle well until powder has fully dissolved. Test temperature Shake bottle well until powder has Leave the bottle to stand for 5 minutes to allow it to Shake the bottle for 20 seconds and then Cool the milk to drinking temperature (approx 37°C) a few drops on to the inside of your wrist – milk should fully dissolved. thicken. Turn the bottle leave to stand for 7 minutes by holding the bottle under be lukewarm. Test temperature by upside down just before feeding. Check temperature to allow it to thicken. Turn the bottle upside down just cold running water. ALWAYS test the temperature of shaking a few drops Step 5 on to the inside of your of feed. Feed immediately. before feeding and test the the milk before feeding by temperature on your wrist. dripping a bit onto the inside Reconstitute SMA® Anti-Reflux as per pack instructions for wrist – milk should be lukewarm. of your wrist; the milk should feel warm, not hot. baby’s age and shake bottle. SMA Anti-Reflux should usually not thicken after it has been prepared.** * The preparation instructions have been taken from label and website information (accessed February 2020). Thicker formula, may require a fast flow teat. SMA Anti-Reflux, because of use of potato starch, usually thickens when the powder is dissolved in water. ** If prepared according to preparation instructions, it should not thicken after the bottle has been prepared. 16 | SMA® Specials Range SMA® Specials Range | 17
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY Mild digestive disorders are common Rome IV diagnostic criteria3 in an infant’s first weeks or months • About 20% of infants are reported by caregivers to have the prolonged periods of crying known as colic20 • At this time an infant’s digestive system is still developing • The prevalence of constipation in the first year of life is 2.9%3 • Mild digestive disorders can present as colic-like symptoms, constipation, wind or crying after a feed Diagnostic criteria for Diagnostic criteria for • Tummy troubles can be difficult for both infant infant colic3 functional constipation3 and parents/caregivers Mild digestive For clinical purposes, must include all Must include 1 month of at least two of discomfort of the following: the following in infants up to 4 years of age: • An infant who is
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA® Comfort Easy to Digest How does SMA® Comfort compare? Infant Milk SMA® Comfort Aptamil Cow & Gate HiPP Easy to Digest22 Comfort 23 Comfort 24 Comfort 25 EASY TO DIGEST Whey:casein 100:0 100:0 100:0 100:0 Contains partially hydrolysed, 100% whey protein which is Partially Partially Partially Partially Type of protein easier to digest than intact protein hydrolysed hydrolysed hydrolysed hydrolysed molecules8. Protein content 1.6 1.5 1.5 1.25 (g/100 ml) NUTRITIONALLY COMPLETE Contains all essential nutrients to No added thickener support babies’ nutritional needs. Lactose (g/100 ml) 3.9 2.7 2.7 2.7 SPECIALLY TAILORED Contains an SN-2-enriched fat Contains SN-2 blend20 and reduced lactose to help manage mild digestive discomfort21. Vegetarian Halal 20 | SMA® Specials Range SMA® Specials Range | 21
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY What is lactose intolerance? Types of lactose intolerance In infants who are unable to metabolise lactose, undigested lactose stays in the Primary lactose intolerance is the most common cause of lactose intolerance intestine, where it can cause diarrhoea, abdominal distension, nausea, bloating worldwide with prevalence related to ethnicity.4 and wind:4,26 Secondary lactose intolerance is common but a temporary cause of diarrhoea.4 • These symptoms can be distressing for both infant and • Secondary lactose intolerance often occurs because parents/caregivers of damage to the intestinal brush border – the site of • Infants fed lactose-free formulas have shown comparable lactase production growth and key nutrient absorption to those fed formula • Secondary lactose intolerance may also develop in containing lactose27,28 some children with gut-related symptoms associated • Studies have also shown that infants with diarrhoea fed with non-IgE-mediated CMPA, which resolves following a lactose-free formula recovered in significantly less time exclusion of cows’ milk protein than those fed a formula containing lactose29-31 • Temporary lactose intolerance is due to immaturity of the Normal Lactose Digestion Lactose intolerant small intestine • Usually improves as affected babies get older and their gut intolerance fully develops Lactose Lactose Small Lactose intestine Congenital lactose intolerance is a rare condition where newborn babies produce very little or no lactase as a result of an inherited genetic fault that runs in families. No/Insufficient Water Lactase Developmental lactose intolerance can be a problem with preterm babies born Lactase before the 34th week.4 Bacteria ferment Glucose Large Galactose intestine Irritation caused Acids and gases 22 | SMA® Specials Range SMA® Specials Range | 23
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA LF® Lactose Free Infant milk How does SMA LF® Lactose Free Infant milk compare? SMA LF® Aptamil Enfamil MANAGES SYMPTOMS OF Lactose Free 33 Lactose Free 34 O-Lac 35 LACTOSE INTOLERANCE For use in conditions where dietary lactose is Whey:casein 60:40 0:100 20:80 contraindicated32 Lactose content (g/100 ml)
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY What’s the difference between cows’ Protein is vital for infants’ growth milk allergy and lactose intolerance? When infants are intolerant to cows’ milk protein, In some infants, cows’ milk can cause the following problems (both of which have an alternative must be found. a defined organic cause but are otherwise unrelated): Under 6 months To ensure infants receive adequate protein, it is acknowledged that there is • Cows’ milk protein allergy (CMPA) a clinical need for soya formulas for infants under 6 months in the following:36,37 • Lactose intolerance • Infants with CMPA or intolerance who refuse extensively There is often confusion between an allergy and an intolerance, both of which hydrolysed or elemental formulas can affect breast- and formula-fed infants. • Infants whose parents want to offer a vegan diet. A food allergy occurs when the immune system reacts to a usually harmless food Vegan parents/caregivers who are unable to breastfeed protein. This immune response leads to the release of substances, such as histamine, resulting in allergic symptoms, such as gut, skin and respiratory symptoms: or choose not to do so • A common food allergy is CMPA which affects approximately • Infants with galactosaemia, galactokinase deficiency 1.8%-7.5% of infants in the first year of life and lactose or sucrose intolerance Contrastingly, a food intolerance does not involve the immune system, and may be From 6 months enzymatic or pharmacological: • The BDA and FSAI state that soya infant milk may be used for babies from 6 months with CMPA and/or lactose • Lactose intolerance is one example of an enzymatic food intolerance when soya is being used/considered intolerance that occurs in infants causing gastrointestinal for the weaning diet36-37 symptoms such as diarrhoea and bloating intolerance Cows’ milk * Child has been shown to have no soya allergy. BDA: British Dietetic Association. FSAI: Food Safety Authority of Ireland. 26 | SMA® Specials Range SMA® Specials Range | 27
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA® Wysoy® Soya Infant Formula SMA® Wysoy® Suitability The only soya-based infant formula in the UK and Ireland.* Suitable for: SMA® Wysoy® Soya Infant Formula is a nutritionally complete, soya protein-based A nutritionally infant formula that is suitable from birth onwards. complete formula.38 It can be used as the sole source of nutrition for infants up to 6 months of age and used as the milk part of a mixed weaning diet. SMA® Wysoy® is lactose free, cows’ milk free and is suitable for vegetarians. Suitable for vegetarians. It is prescribable for milk protein intolerance, lactose and sucrose intolerance, galactosaemia and galactokinase deficiency. Not suitable for: 1. Soya protein intolerance/allergy. 2. The inborn error of metabolism; phenylketonuria. For suitability in vegan diets, please contact our SMA Careline. *As of July 2015. 28 | SMA® Specials Range SMA® Specials Range | 29
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY Supporting infants at risk of allergy Supporting infants at risk of allergy • SMA H.A.® Infant Milk uses a unique two step process to reduce the level of allergenicity in the protein: a heat treatment and a two stage enzymatic hydrolysis (a process which imitates natural digestion) One in three babies has a family history of allergy39 2. Specific 1. Heat enzymatic treatment • Allergies are increasing – with a three-fold increase hydrolysis in the prevalence of atopic eczema over 15 years40 Whole protein Unfolds the protein Cuts the protein • 60–80% of babies with two parents with allergy will develop allergies41 • Supporting infants at risk of allergy – if exclusive breastfeeding is not possible, formulas that have been clinically proven to • This unique process cuts the proteins in exactly the right place to reduce allergenicity while retaining some larger protein strands to help train reduce the risk of allergy are recommended41 the immune system42 Family history of allergy 30 | SMA® Specials Range SMA® Specials Range | 31
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY SMA H.A.® Infant Milk Supporting infants at risk of allergy SMA H.A.® is an infant milk clinically proven to reduce the risk of developing What do the guidelines say? eczema in infants with a family history of allergy.43 EAACI Food Allergy and Anaphylaxis Guidelines (2014)41 In SMA H.A.®, cows’ milk “If breastfeeding is insufficient or not possible for the first 4 months, infants at high proteins have been broken risk can be recommended a hypoallergenic formula with documented preventive up into smaller pieces, effect for the first 4 months of life” which reduces the risk of infants developing an allergic response. ESPGHAN (2014)44 “In high-risk infants, when breast-feeding is not possible, hydrolysates of documented Partially hydrolysed whey safety and efficacy have an indication in infant feeding up to the age 4 to 6 months.” protein formula containing 1.3 g protein per 100 ml. SMA H.A.® Infant Milk reduces the risk of developing eczema by over 50% in the first year of life;43 it is easy to digest and available on the Healthy Start scheme (UK only). Important: • SMA H.A.® Infant Milk should NOT be used if a baby has already been diagnosed with allergy to cows’ milk protein or is suspected of already having an allergy to cows’ milk protein • Use from first formula feed 32 | SMA® Specials Range SMA® Specials Range | 33
BREASTFEEDING IS BEST FOR BABIES INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY References: 1. Iacono G et al. Dig Liv Dis 2005; 37(6): 432–438. 2. Vandenplas Y et al. JPGN 2015 (61); 5: 531–537. 3. Benninga M et al. Gastroenterology 2016; IMPORTANT NOTICE: The World Health Organisation (WHO) has recommended that pregnant women and new mothers be informed on the benefits 150: 1443–1455. 4. Heyman MB. Pediatrics 2006; 118(3): 1279–1286. 5. NICE (2019). Clinical Knowledge Summaries: Cows’ milk protein allergy in children. Available and superiority of breastfeeding – in particular the fact that it provides the best nutrition and protection from illness for babies. Mothers should be given at https://cks.nice.org.uk/cows-milk-protein-allergy-in-children#!topicsummary (accessed February 2020). 6. Armaforte E et al. International Dairy Journal 2010; guidance on the preparation for, and maintenance of, lactation, with special emphasis on the importance of a well-balanced diet both during pregnancy 20: 715–723. 7. Martin CR et al. Nutrients 2016; 8(5): 279. 8. Billeaud C et al. Eur J Clin Nutr 1990; 44: 577–583. 9. NHS (2019). Types of formula milk. Available and after delivery. Unnecessary introduction of partial bottle-feeding or other foods and drinks should be discouraged since it will have a negative effect at https://www.nhs.uk/conditions/pregnancy-and-baby/types-of-infant-formula/ (accessed February 2020). 10. DoH (2006) https://www.hse.ie/eng/services/ on breastfeeding. Similarly, mothers should be warned of the difficulty of reversing a decision not to breast-feed. Before advising a mother to use an publications/children/unit-7-food-and-nutrition.pdf (accessed February 2020). 11. NICE (2015). Gastro-oesophageal reflux disease in children and young people. infant formula, she should be advised of the social and financial implications of her decision: for example, if a baby is exclusively bottle-fed, more than Available at https://www.nice.org.uk/guidance/ng1 (accessed February 2020). 12. Sidnell A et al. British Nutrition Foundation Nutrition Bulletin 2009; 34: 395–400. one can (400 g) per week will be needed, so the family circumstances and costs should be kept in mind. Mothers should be reminded that breast milk 13. Indrio F, et al. Effect of a Partially Hydrolysed Whey Infant Formula Supplemented with Starch and Lactobacillus reuteri DSM 17938 on Regurgitation and Gastric is not only the best, but also the most economical food for babies. If a decision to use an infant formula is taken, it is important to give instructions on Motility. Nutrients 2017, 9, 1181. 14. SMA® Anti-Reflux data card. Available at https://www.smahcp.co.uk/formula-milk/anti-reflux-formula (accessed February correct preparation methods, emphasising that unboiled water, unsterilised bottles or incorrect dilution can all lead to illness. SMA® Wysoy® milk-free 2020). 15. Aptamil Anti-Reflux datacard (June 2018). Available at https://eln.nutricia.co.uk/range/specialist-milks/ (accessed February 2020). 16. Cow & Gate formula is intended to meet the nutritional needs of babies and children who are intolerant to cows’ milk protein, lactose or sucrose. Soya infant formulae Anti-reflux datacard. Available at https://eln.nutricia.co.uk/range/specialist-milks/ (accessed February 2020). 17. Hipp Organic anti-reflux datacard. Available at are not recommended for preterm babies or those with kidney problems, where medical guidance should always be sought. SMA® PRO Follow-on https://www.hipp4hcps.co.uk/resources/helpsheets/data-sheets/ (accessed February 2020). 18. Enfamil AR datacard. Available at https://hcp.nutramigen.co.uk/ Milk and SMA® Organic Follow-on Milk are only suitable for babies over 6 months as part of a mixed diet. They should not be used as a substitute files/6614/6304/6719/Filofax_Insert_UK_June_2015_8.pdf (accessed February 2020). 19. St James-Roberts I et al. Early Dev Parent 1995; 4: 177–189. 20. Yao for breast milk during the first 6 months of life. The decision to start weaning or to use a follow-on milk before 6 months, should be made only on the M et al. J Pediatr Gastroentrol Nutr 2010; 50(Suppl 2): PO-N-444. 21. Infante D et al. World J Gastroenterol 2011; 17: 2104–2108. 22. SMA® Comfort Easy to Digest advice of a doctor, midwife, health visitor, public health nurse, dietitian or pharmacist, based on baby’s individual needs. SMA® PRO Growing up Infant Milk datacard. Available at https://www.smahcp.co.uk/formula-milk/comfort-infant-milk (accessed February 2020). 23. Aptamil Comfort datacard. Available at Milk is suitable for young children from 1-3 years, as part of a healthy balanced diet and it is not a breast milk substitute. SMA® Organic Growing https://eln.nutricia.co.uk/product-info/aptamil-comfort-from-birth-2/ (accessed February 2020). 24. Cow & Gate Comfort datacard. Available at https://eln.nutricia. up Milk is suitable for young children from the 12th month, as part of a healthy balanced diet and it is not a breast milk substitute. The following co.uk/product-info/cow-gate-comfort-from-birth-2/ (accessed February 2020). 25. Hipp Organic Comfort Milk datacard. Available at https://www.hipp4hcps.co.uk/ products must be used under medical supervision. SMA® Anti-Reflux is a special formula intended for the dietary management of bottle-fed resources/helpsheets/data-sheets/ (accessed February 2020). 26. Thomas B, Bishop J (eds.) Manual of Dietetic Practice. Fourth Edition. Oxford: Blackwell Publishing babies when significant reflux (regurgitation) is a problem. It is suitable as the sole source of nutrition up to 6 months of age, and in conjunction with 2007: 458–459. 27. Moya M et al. Acta Paediatr 1999; 88: 1211–1215. 28. Heubi J et al. J Am Diet Assoc 2000; 100: 212–217. 29. Saneian H et al. Iran J Pediatr solid food up to 12 months of age. If the baby’s reflux does not improve within 2 weeks of starting SMA® Anti-Reflux, or if the baby fails to thrive, 2012; 22: 82–86. 30. Xu JH et al. Contemp Pediatr 2009; 11: 532–536. 31. Vandenplas Y et al. Nutrition 2013; 29: 184–194. 32. NHS (2019). Lactose Intolerance. the family doctor should be consulted. SMA LF® is a lactose-free milk based formula for babies and young children who are intolerant to lactose or Available at https://www.nhs.uk/conditions/lactose-intolerance/ (accessed: January 2020). 33. SMA® LF ® Lactose Free Infant Milk datacard. Available at https:// sucrose, or who are experiencing symptoms such as diarrhoea, tummy ache or wind caused by temporary lactose intolerance. It is suitable as the sole www.smahcp.co.uk/formula-milk/lactose-free-formula (accessed February 2020). 34. Aptamil Lactose Free datacard. Available at: https://www.eln.nutricia.co.uk/ source of nutrition up to 6 months of age, and in conjunction with solid food up to 18 months of age. SMA High Energy® is a milk based formula for media/4354/datacard_aptamil_ lactose_free.pdf (accessed December 2018). 35. Mead Johnson, Enfamil 0-Lac, information from Mead Johnson customer careline, the dietary management of babies and young children with medically determined high energy requirements as identified by a healthcare professional. 2016. 36. British Dietetic Association. Paediatric Group Position Statement Use of Infant Formulas based on Soy Protein for Infants. BDA, April 2019. 37. Food Safety It is suitable as the sole source of nutrition up to 6 months of age, and in conjunction with solid food up to 18 months of age. SMA High Energy® is not Authority of Ireland, Best Practice for Infant Feeding in Ireland (2012). Available at https://www.lenus.ie/handle/10147/252765 (accessed February 2020). 38. SMA® intended for use with preterm babies, for whom fortified breast milk or a low birthweight formula such as SMA Gold Prem® 1 is more appropriate. Wysoy® Soya Infant Formula datacard. Available at https://www.smahcp.co.uk/formula-milk/soya-infant-formula (accessed February 2020). 39. Bergmann RL et al. SMA® Breast Milk Fortifier is a nutritional supplement designed to be added to expressed breast milk for the dietary management of feeding preterm Clin Exp Allergy 1997; 27: 725–760. 40. Eichenfield LF et al. Pediatrics 2003; 111: 608–616. 41. Muraro A et al. EAACI Food Allergy and Anaphylaxis Guidelines. low birthweight babies. SMA Gold Prem® 1 is a special formula intended for the dietary management of preterm low birthweight babies who are not Primary prevention of food allergy. Allergy 2014; 69(5): 590–601. 42. Jost R et al. Bibl Nutr Dieta 1991; 48: 127–137. 43. von Berg A et al. J Allergy Clin Immunol solely fed breast milk. It is suitable for use as the sole source of nutrition for preterm babies from birth. SMA Gold Prem® 1 is not intended for use with 2008; 121: 1442–1447. older preterm babies, for whom a special catch-up formula such as SMA Gold Prem® 2 is more appropriate. SMA Gold Prem® 2 is a special catch-up formula intended for the dietary management of preterm low birthweight babies who are not solely fed breast milk. It is a nutritionally complete formula for use on discharge from hospital or when a low birthweight formula is no longer appropriate. It is suitable for use as the sole source of nutrition up to 6 months corrected age. SMA Gold Prem® 2 is not intended for use with newborn preterm babies, for whom fortified breast milk or a low birthweight formula such as SMA Gold Prem® 1 is more appropriate. NWP089; CHLWP022; FRJNP008; IRFI1P002; NWH200-1; IRGMAP005; FRJNP008; NLNW031; DSHL003-1; DENWHS016; DSS005-1; DEDWHL008; DSHL001-2; DSH204; DSH001; NW102; LE136; JN070; NW101; LE135 ;JN069 NWHP315F; NWHP315G; NWHP315H 34 | SMA® Specials Range SMA® Specials Range | 35
INFORMATION FOR HEALTHCARE PROFESSIONAL USE ONLY BREASTFEEDING IS BEST FOR BABIES SMA® Nutrition’s Specialist formula range: Individually tailored to meet the challenges of specific infant feeding issues The broadest, most comprehensive range of solutions for feeding issues Based on latest advances in scientific and clinical research Wide availability in retail or to be ordered via pharmacy SMA Nutrition, 1 City Place, Gatwick, RH6 0PA In the Republic of Ireland: SMA Nutrition, 3030 Lake Drive, Citywest Business Campus, Dublin 24, Ireland Learn more: UK 0800 081 81 80 www.smahcp.co.uk ROI 1800 931 832 www.smahcp.ie SMA® Nutrition UK and Ireland ®Reg. Trademark of Société des Produits Nestlé S.A. ZTC4732/02/20
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