PROGRAM October 4-5, 2018 Beaumont Children's Royal Oak, Michigan - Midwest Society for Pediatric Research - Medpub
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Midwest Society for Pediatric Research PROGRAM October 4-5, 2018 Beaumont Children's Royal Oak, Michigan Co-Hosted by: Abstract Deadline: Friday, June 8, 2018 Registration Deadline: September 21, 2018 Co-Hosted by:
PROGRAM‐AT‐A‐GLANCE 59th Annual Midwest Society for Pediatric Research Scientific Meeting Beaumont Children's OUWB Auditorium, Beaumont Children's Royal Oak, MI Meeting TIME ACTIVITY AND LOCATION WEDNESDAY, OCTOBER 3, 2018 4:45 pm – 6:15 pm MWSPR Council Meeting Beaumont, Royal Oak – John D. Labriola Conference Room 6:30 pm – 9:30 pm MWSPR Council Dinner TBD, Royal Oak THURSDAY, OCTOBER 4, 2018 7:00 am – 8:00 am MWSPR Registration Beaumont, Royal Oak ‐ Administration Lobby 7:00 am – 8:00 am Continental Breakfast Beaumont, Royal Oak ‐ OUWB Classrooms 8:00 am – 11:45 am MWSPR Plenary Session I Beaumont, Royal Oak ‐ OUWB Auditorium 11:45 am – 12:00 pm MWSPR Business Meeting for Members Beaumont, Royal Oak ‐ OUWB Auditorium 12:00 pm – 1:30 pm Founder and Sutherland Award Luncheon Beaumont, Royal Oak ‐ OUWB Classrooms 1:30 pm – 4:30 pm MWSPR Plenary Session II Beaumont, Royal Oak ‐ OUWB Auditorium 4:30 pm – 4:45 pm Poster Set‐up Beaumont, Royal Oak, Suite 100 4:45 pm – 6:15 pm Reception and Combined Poster Session Beaumont, Royal Oak ‐ Suite 100 6:15 pm Poster Take Down (immediately following Session) FRIDAY, OCTOBER 5, 2018 7:00 am – 8:00 am MWSPR Registration Beaumont, Royal Oak ‐ Administration Lobby 7:00 am – 8:00 am Continental Breakfast Beaumont, Royal Oak ‐ OUWB Classrooms 7:00 am – 8:00 am Trainee Breakfast Professional Societies and Networking Brian Berman Chair, Pediatrics Beaumont Children’s Beaumont, Royal Oak ‐ OUWB Auditorium 8:00 am – 12:00 pm MWSPR Plenary Session III Beaumont, Royal Oak ‐ OUWB Auditorium 12:15 pm – 1:30 pm Kenny, Metcoff, and Student Research Award Luncheon Beaumont, Royal Oak ‐ OUWB Classrooms 1
This meeting has been made possible in part through the generosity of our supporters and the research efforts of the faculty, fellows, residents, medical and graduate students. We are very proud of the extent and breadth of our research programs and activities, and we trust that you will enjoy the activities of the meeting. We would like to thank the abstract reviewers for their time and effort in the review process in this important endeavor. Campus Map: MWSPR Planning Committee Laura Haneline, MD – President Neal Blatt, MD, PhD – President‐Elect Carl Backes, MD – Secretary Noah Hillman, MD – Treasurer Acknowledgements The Midwest Society for Pediatric Research would like to thank the following organizations for their generous support: Abbott Nutrition Beaumont Children's Mead Johnson Nutrition 2
59th Annual Midwest Society for Pediatric Research Scientific Meeting THURSDAY, OCTOBER 4, 2018 8:00 am – 6:00 pm OUWB Auditorium, Beaumont Children's 7:00‐8:00 am REGISTRATION AND CONTINENTAL BREAKFAST 8:00‐8:05 WELCOME AND INTRODUCTION Laura Haneline, President 8:05 State‐of‐the‐Art Speaker CURRENT UPDATE ON FETAL SURGERY. Anthony Odibo, MD, MSCE, FRCOG, FACOG Professor, College of Medicine Obstetrics & Gynecology, University of South Florida MWSPR PLENARY SESSION I OUWB Auditorium, Beaumont Children's Presiding: Sarah Haskell and Steven Olsen 9:00 GENETIC DEFECTS IN SHROOM3 LEAD TO CONGENITAL HEART DEFECTS. M Durbin and SM Ware, Indianapolis, IN. Indiana University School of Medicine Abstract 1 9:15 CARDIAC INJURY CAUSED BY SEPSIS IN A NEONATAL MOUSE MODEL. A Rajgarhia, H Menden, S Mabry, A Kats, and V Sampath, Kansas City, MO. Children's Mercy, Kansas City ‐ UMKC School of Medicine Abstract 2 9:30 TARGETING RIBONUCLEOTIDE REDUCTASE AND PROTEIN SYNTHESIS IN EWING SARCOMA TUMORS. DJ Gordon, SL Koppenhafer, KL Goss, and WW Terry, Iowa City, IA. University of Iowa Abstract 3 9:45 ALTERED FETAL ISLET TRANSCRIPTOME PREDICTS ISLET DYSFUNCTION IN OFFSPRING EXPOSED TO IN‐UTERO HYPERGLYCEMIA. K Kua and JJ Casasnovas, Indianapolis, IN. Indiana University School of Medicine Abstract 4 10:00 – 10:15 am BREAK Presiding: David McCulley and Sara Ramel 10:15 OUTCOMES FOLLOWING TWO DIFFERENT TREATMENT APPROACHES (PROACTIVE VERSUS SELECTIVE) FOR INFANTS BORN AT 22 WEEKS OF GESTATION. C Mitchell, L Walsh, C Backes, F Soderstrom, J Agren, R Sindelar, C Bartlett, B Rivera, J Iams, H Frey, J Richter, E Shepherd, L Nelin, and E Normann, Columbus, OH and Uppsala, Sweden. Nationwide Children's Hospital/The Ohio State University Abstract 5 3
10:30 ELEVATED CIRCULATING NEUTROPHIL‐LYMPHOCYTE RATIOS IDENTIFY PRETERM NEONATES EXPOSED TO HISTOLOGIC CHORIOAMNIONITIS AND EARLY‐ONSET SEPSIS. A Singareddy, PL Sweeney, A Lee, P Buchanan, HJ Williams, NJ Hillman, and JM Koenig, Saint Louis, MO and Memphis, TN. Saint Louis University Abstract 6 10:45 CARDIOMETABOLIC CONSEQUENCES AFTER EXPOSURE TO EXCESS PRENATAL FUELS. EJ Louwagie, TD Larsen, and ML Baack, Sioux Falls, SD. University of South Dakota Abstract 7 11:00 A RETROSPECTIVE SEGMENTATION ANALYSIS OF PLACENTAL VOLUME BY MAGNETIC RESONANCE IMAGING FROM FIRST TRIMESTER TO TERM GESTATION. RL Leon and BP Brown, Indianapolis, IN. Indiana University School of Medicine Abstract 8 11:15 PLACENTAL TRANSFUSION IMPLEMENTAION AND OUTCOMES: A SINGLE CENTER EXPERIENCE 2010‐2016. C Njinimbam, F Soltys, and WA Engle, Indianapolis, IN. Indiana University School of Medicine Abstract 9 11:30 A GENETIC MODEL OF DIAPHRAGMATIC HERNIA, LUNG HYPOPLASIA, AND PULMONARY HYPERTENSION. DJ McCulley, M Brix, H Bremer, G Stokes, Y Shen, and W Chung, Madison, WI and New York, NY. University of Wisconsin – Madison Abstract 10 11:45 MWSPR BUSINESS MEETING FOR NON‐TRAINEES 12:00 FOUNDER AND SUTHERLAND AWARD LUNCHEON Beaumont, Royal Oak ‐ OUWB Classrooms Founder Award Recipient Scott C. Denne, MD Indiana University School of Medicine Introduction by: Edward A. Liechty, MD MWSPR PLENARY SESSION II Presiding: Lyndsey Harshman and Steven McElroy 1:30 ABNORMAL DIASTOLIC BLOOD PRESSURE TRENDS IN VERY LOW BIRTH WEIGHT INFANTS FOLLOWING ACUTE KIDNEY INJURY. K Kellner, A Pham, A Schwartz, and N Srinivasan, Chicago, IL. University of Illinois Abstract 11 1:45 TRANSCATHETER PATENT DUCTUS ARTERIOSUS (PDA) CLOSURE IN LOWER WEIGHT INFANTS (
2:00 ADRENOCORTICOTROPIC HORMONE STIMULATES VASCULAR ENDOTHELIAL GROWTH FACTOR RELEASE IN HEALTHY CHILDREN AND ADOLESCENTS. RA Heksch and RP Hoffman, Columbus, OH. Nationwide Children's Hospital Abstract 13 2:15 NITRIC OXIDE DONOR INCREASES PDE3A PROTEIN EXPRESSION IN HUMAN PULMONARY ARTERY SMOOTH MUSCLE CELLS. JA Dillard, X Meng, and B Chen, Columbus, OH. Nationwide Children’s Hospital/The Ohio State University Abstract 14 2:45 THE EXPRESSION OF THE ERBB FAMILY IN HUMAN PULMONARY MICROVASCULAR ENDOTHELIAL CELLS. CS Regan, Y Jin, C Pool, Y Liu, B Chen, and LD Nelin, Dublin, OH and Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 15 3:00 – 3:15 pm BREAK 3:15 HIGH OSMOLALITY FORMULA INDUCES INTESTINAL INJURY AND MICROBIOME SHIFTS SIMILAR TO NEC. SR Lueschow, S Kern, H Gong, and SJ McElroy, Elmwood, IL and Iowa City, IA. University of Iowa Abstract 16 3:30 NOVEL SIGIRR TRANSGENIC MICE ENCODING MUTATION FOUND IN HUMAN NEC HAVE DECREASED INTESTINAL EXPRESSION OF THE MICRORNAS MIR146A AND MIR155 AND INCREASED INFLAMMATION. W Yu, HW Menden, SW Xia, A Cuna, and V Sampath, Kansas City, MO. Children's Mercy Hospital Abstract 17 3:45 THE METABOLOMICS OF NECROTIZING ENTEROCOLITIS: INFLAMMATORY AND TRYPTOPHAN METABOLISM PATHWAY DYSREGULATION AND BIOMARKER DEVELOPMENT. CA Sibbald, MM Goree, WE Lanik, B Mihi, Q Gong, ML Mara, and M Good, St. Louis, MO. Washington University in St. Louis Abstract 18 4:00 HUMAN CATHELICIDIN LL‐37 SIGNIFICANTLY DECREASES INTESTINAL INJURY SCORES IN EXPERIMENTAL NECROTIZING ENTEROCOLITIS. JN Berger, H Gong, and SJ McElroy, Iowa City, IA. University of Iowa Abstract 19 4:15 PANETH CELL DEVELOPMENT STARTS AFTER LIMITS OF VIABILITY. AH Stanford, H Gong, MA Mara, WE Lanik, Q Gong, M Good, and SJ McElroy, Iowa City, IA and St Louis, MO. University of Iowa Abstract 20 4:30 RECEPTION AND COMBINED POSTER SESSION – Beaumont, Royal Oak ‐ Suite 100 See page 8 for posters 5
FRIDAY, OCTOBER 5, 2018 OUWB Auditorium ‐ Beaumont Children's 7:00 am – 1:30 pm 7:00 MWSPR REGISTRATION 7:00 TRAINEE BREAKFAST SESSION Professional Societies and Networking Brian Berman, MD Chair, Pediatrics Beaumont Children’s Beaumont, Royal Oak ‐ OUWB Classrooms MWSPR PLENARY SESSION III 8:00 am – 12:00 pm Presiding: Craig Garfield and Ben Kopp 8:00 State‐of‐the‐Art Speaker 50 Years PERSPECTIVE ON THE TREATMENT OF BABIES WITH JAUNDICE. M. Jeffrey Maisels, MD Professor, Department of Pediatrics Oakland University William Beaumont School of Medicine 9:00 EXOME SEQUENCING IDENTIFIES STAB2 DEFICIENCY AS A GENETIC RISK FOR VENOUS THROMBOEMBOLIC DISEASE. KC Desch, AB Ozel, and D Ginsburg, Ann Arbor, MI. University of Michigan Abstract 21 9:15 INTRAPLEURAL ADMINISTRATION OF TISSUE PLASMINOGEN ACTIVATOR AND DORNASE ALFA IN PEDIATRIC PATIENTS WITH EMPYEMA. V Rajanna, JC Chan, PB Khandhar, and NM Novotny, Beverly Hills, MI, Rochester, MI, and Royal Oak, MI. Oakland University William Beaumont School of Medicine Abstract 22 9:30 DYNAMIC REGULATION OF VESICULAR TRAFFICKING BY ALTERED STEROL HOMEOSTASIS: IMPLICATIONS FOR CHOLESTEROL SYNTHESIS DISORDERS. EH Anderson, JG Kerkvliet, AD Hoppe, and KR Francis, Sioux Falls, SD and Brookings, SD. Sanford School of Medicine‐University of South Dakota Abstract 23 9:45 USING ACCESSORY GENOMIC ELEMENTS OF PSEUDOMONAS AERUGINOSA TO PREDICT ERADICATION FOLLOWING NEW INFECTION IN CYSTIC FIBROSIS. M Soneji, E Ozer, M Kandpal, N Mayer‐Hamblett, PK Singh, and AR Hauser, Chicago, IL and Seattle, WA. Northwestern University Abstract 24 10:00 – 10:15 am BREAK 6
Presiding: Ulrike Mietzsch and Noah Hillman 10:15 INTERACTIONS BETWEEN ANGIOTENSIN RECEPTORS, TRANSFERRIN RECEPTORS, AND MULTI‐LIGAND RECEPTORS IN GROWTH RESTRICTED FETAL KIDNEYS. HA Prosek, AS Bauer, SE Blohowiak, BR Pattnaik, and PJ Kling, Madison, WI. University of Wisconsin‐Madison Abstract 25 10:30 ROLE OF ERYTHROPOIETIN IN ACUTE KIDNEY INJURY IN NEONATAL RATS. KM Trieglaff, MW Harer, SE Blohowiak, and PJ Kling, Madison, WI. University of Wisconsin‐ Madison Abstract 26 10:45 ACTIVE HYPOTHERMIA DURING TRANSPORT REDUCES TIME TO TREATMENT IN NEONATES WITH HIE. KE Krause, RL Leon, RA Shope, EA Strait, MB Koch, and U Mietzsch, Indianapolis, IN. Indiana University School of Medicine Abstract 27 11:00 ULTRASOUND ASSESSMENT OF BODY COMPOSITION IN THE NEONATAL INTENSIVE CARE UNIT. M Hickey, E Nagel, L Teigen, E Demerath, C Earthman, T Holm, and S Ramel, Minneapolis, MN. University of Minnesota Abstract 28 11:15 RELATIONSHIPS OF NUTRITION AND ILLNESS IN THE FIRST WEEK OF LIFE TO BODY COMPOSITION AT HOSPITAL DISCHARGE IN VERY LOW BIRTH WEIGHT PRETERM INFANTS. SE Ramel, J Haapala, and EW Demerath, Shoreview, MN and Minneapolis, MN. University of Minnesota Abstract 29 11:30 DUAL SPECIFICITY PHOSPHATASE‐1 DEFICIENCY STRENGTHENS IMMUNE DEFENSE AGAINST FUNGAL INFECTION. MM Talavera, S Crowell, T Juan, V Kim, LD Nelin, J Zhang, and Y Liu, Dublin, OH and Columbus, OH. Nationwide Children's Hospital Abstract 30 11:45 NEONATES ARE UNIQUELY SUSCEPTIBLE TO ESCHERICHIA COLI K1 SEPSIS DUE TO EXCESS IRON. JR Bermick, K Michels, N Lambrecht, W Carson, S Kunkel, M Schaller, and N Lukacs, Ann Arbor, MI. University of Michigan Abstract 31 12:15 pm – 1:30 pm MWSPR Kenny, Metcoff, and Student Research Award Luncheon Sponsored by Abbott Nutrition Beaumont, Royal Oak ‐ OUWB Classrooms 7
RECEPTION AND COMBINED POSTER SESSION THURSDAY, OCTOBER 4, 2018 Beaumont, Royal Oak ‐ Suite 100 Poster Abstract Number Number 1 GABAPENTIN USE FOR HOSPITALIZED NEONATES. HH Abdi, NL Maitre, KL Benninger, ME Hester, and JL Slaughter, Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 32 2 NOVEL METHOD OF OXYTOCIN EXTRACTION IN HUMAN PLASMA. CO Adegboro, NW York, PJ Kling, and BR Pattnaik, Madison, WI. University of Madison‐ Wisconsin Abstract 33 3 UNDERSTANDING PREECLAMPSIA THROUGH COMBINATON DOSING OF ANGIOGENIC FACTORS ON HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS. D Adu and DS Boeldt, Madison, WI. University of Wisconsin‐Madison Abstract 34 4 SOUND IN THE NICU: IS A SINGLE ROOM THE ANSWER? D Aggarwal, D Rao, and S Chawla, Detroit, MI and Troy, MI. Wayne State University School of Medicine Abstract 35 5 IMAGING FOR PEDIATRIC BLUNT ABDOMINAL TRAUMA ‐ DIFFERENT PREDICTION RULES, IS THE OUTCOME THE SAME? TS Ahn, A Ozcan, and M Menoch, Berkley, MI and Royal Oak, MI. Beaumont Children's Hospital Abstract 36 6 CHILDREN WITH COMPLEX FEBRILE SEIZURES: IS HOSPITAL ADMISSION NECESSARY? MC Aldana, B Webb, M Naqvi, R Batshon, C Agu, U Sethuraman, and N Kannikeswaran, Dearborn, MI and Detroit, MI. Children's Hospital of Michigan Abstract 37 7 PLACENTAL PATHOLOGY AND ASSOCIATION WITH PATTERN OF BRAIN INJURY ON MAGNETIC RESONANCE IMAGING IN PATIENTS TREATED WITH THERAPEUTIC HYPOTHERMIA FOR HYPOXIC ISCHEMIC ENCEPHALOPATHY. M Aye, P Agarwal, D Altinok, F Qureshi, S Jacques, A Farooqi, and S Shankaran, Detroit, MI. Children's Hospital of Michigan Abstract 38 8 MR IMAGING ASSESSMENT TOOL FOR WHITE MATTER INJURY AFTER DEEP MEDULLARY VEIN THROMBOSIS AND INFARCTION IN NEONATES. KL Benninger, NL Maitre, L Ruess, and JA Rusin, Columbus, OH. Nationwide Children's Hospital/Ohio State University Abstract 39 9 DELAYED PANETH CELL DEVELOPMENT WITH HEREGULIN‐1 IN IMMATURE MICE. JN Berger, H Gong, MR Frey, and SJ McElroy, Iowa City, IA and Los Angeles, CA. University of Iowa Abstract 40 10 SURIVIVAL AND SHORT TERM RESPIRATORY OUTCOMES OF
11 DECREASED ANTIBIOTIC USE IN WELL‐APPEARING INFANTS EXPOSED TO MATERNAL CHORIOAMNIONITIS. LE Cummings, C Miner, LB Churchman, G Akangire, J Weiner, and J Jackson, Kansas City, MO and Shawnee Mission, KS. Children's Mercy Hospital Abstract 42 12 PRIMARY BURKITT LYMPHOMA IN A CHILD WITH DOWN SYNDROME. I Datta, S Roy, JW Taub, and S Savasan, Northville, MI and Detroit, MI. Wayne State University/Children's Hospital of Michigan Abstract 43 13 EARLY FINDINGS OF MYOCARDIAL FIBROSIS ON CARDIAC MRI IN A 9 YEAR OLD FEMALE WITH LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2C. A Dupont, I Gonzalez, E McCormick and A Bilolikar, Royal Oak, MI. Beaumont Children's Abstract 44 14 AN INFANT WITH CARDIAC VALVULAR PROBLEMS AND RESPIRATORY DISTRESS: THE HEART MAY NOT BE THE CULPRIT. A Dupont, and A Prabhu, Royal Oak, MI. Beaumont Children's Abstract 45 15 THE EFFECT OF STATEWIDE ELECTRONIC REPORTING ON PULSE OXIMETRY SCREENING IN NEWBORNS. MS Engel, A Phimister, A Gaviglio, L Spector, and JL Lohr, Plymouth, MN, Minneapolis, MN, and St. Paul, MN. University of Minnesota Abstract 46 16 OFFSPRING OUTCOMES IN PREGNANCIES COMPLICATED BY MATERNAL CONGENITAL HEART DISEASES: A SYSTEMATIC REVIEW AND META‐ANALYSIS OF OBSERVATIONAL STUDIES. MD Essien, LV Ghimire, C Chen, and F Chou, Kansas City, KS and Laconia, NH. University of Kansas Medical Center Abstract 47 17 MEAN PLATELET VOLUME MAY BE USED TO GUIDE ANTIBIOTICS USE IN NEWBORNS WITH THROMBOCYTOPENIA AND LEUKOPENIA. MD Essien, C Chen, and F Chou, Kansas City, KS. University of Kansas Medical Center Abstract 48 18 WEIGHT GAIN DURING PREGNANCY, CHILD BMI AND INFLAMMATION AT ONE YEAR OF AGE. J Gannon, AJ Pollock, SE Blohowiak, and DB Allen, Madison, WI. University of Wisconsin‐ Madison Abstract 49 19 EFFECTS OF GENETIC MUTATIONS ON THE RISK FOR NEONATAL COMPLICATIONS. KM Gnona, WC Stewart, P White, M Klebanoff, and I Buhimschi, Columbus, OH. Nationwide Children’s Hospital Abstract 50 20 RESPIRATORY SYNCYTIAL VIRUS: MORE THAN JUST BRONCHIOLITIS. R Greene, DR Gurkha, N El‐Wiher, and AS Prabhu, Royal Oak, MI. Beaumont Children's Abstract 51 21 UTILITY OF PREOPERATIVE CRANIAL AND ABDOMINAL IMGAING IN CONGENITAL HEART DISEASE INFANTS. V Gunasekaran, G Natarajan, and S Aggarwal, Detroit, MI. Wayne State University Abstract 52 9
22 A 4 YEAR OLD CHILD WITH VIRAL MYOCARDITIS. A Gupta, T Eckenswiller and D Nguyen, Royal Oak, MI. Beaumont Children's Abstract 53 23 ORGANOAXIAL GASTRIC VOVULUS IN A HEALTHY CHILD. GK Jones, B Akay and L Adams, Royal Oak, MI. Beaumont Children's Abstract 54 24 BETA‐PROPELLER PROTEIN‐ASSOCIATED NEURODEGENERATION (BPAN) DETECTED IN A CHILD WITH EPILEPTIC SPASMS. G Kaleka, A Krishnan, and ME McCormick, Royal Oak, MI. Beaumont Children's Abstract 55 25 PREPUBESCENT PEDIATRIC PATIENT WITH PNEUMOTHORAX IN DIABETIC KETOACIDOSIS. G Kennady and P Khandhar, Royal Oak, MI. Beaumont Children's Abstract 56 26 SAN LUIS VALLEY SYNDROME IN A NON HISPANIC PATIENT ‐ A CASE REPORT WITH NEUROIMAGING FINDINGS. G Kennady, A Krishnan, and ME McCormick, Royal Oak, MI. Beaumont Children's Abstract 57 27 ATYPICAL PRESENTATION OF MICROSCOPIC POLYANGIITIS IN A YOUNG MAN WITH SHUNTED CONGENITAL HYDROCEPHALUS. J Kim, J Shah, and K Cashen, Detroit, MI. Wayne State University Abstract 58 28 PEDIATRIC RESIDENCY GRADUATE PREPAREDNESS FOR NEONATAL‐PERINATAL MEDICINE FELLOWSHIP: THE PERSPECTIVE OF FIRST YEAR FELLOWS. LJ Korbel, CH Backes, B Rivera, C Mitchell, M Carbajal, KM Reber, and EM Bonachea, Columbus, OH and Houston, TX. Nationwide Children's Hospital/The Ohio State University Abstract 59 29 AN INDIVIDUAL HEALTH PLAN FOR CHILDREN WITH MEDICAL COMPLEXITY ‐ AN ASSESSMENT OF CAREGIVER EXPERIENCES. J Lammert, A Zabih, A Tanios, D Halloran, S Stricklin, and P Buchanan, Brentwood, MO, St. Louis, MO, and Columbia, MO. Saint Louis University Abstract 60 30 INCIDENCE AND ETIOLOGY OF EXTREME THROMBOCYTOPENIA IN A NEONATAL POPULATION. TJ LaRouere and B Berman, Royal Oak, MI. Children's Hospital of Michigan Abstract 61 31 UNDERSTANDING PARENTS’ INFORMATIONAL NEEDS IN THE PEDIATRIC INTENSIVE CARE UNIT. NM Laudato, L Yagiela, and KL Meert, Detroit, MI. Wayne State University Abstract 62 32 OPTIMAL TIMING OF HYPOTHYROIDISM NEWBORN SCREENS IN VERY LOW BIRTHWEIGHT (VLBW) NEONATES. S Levin, G Chan, A Molefe, and S Amin, Maywood, IL. Loyola University Medical Center Abstract 63 33 WEETOS: EDIBLE CANNABINOIDS AND A CHILD WITH LETHARGY. J Lim, M Steck and P Khandhar, Royal Oak, MI. Beaumont Children's Abstract 64 10
34 USE OF NEURALLY ADJUSTED VENTILATORY ASSIST IN INFANTS WITH CONGENITAL DIAPHRAGMATIC HERNIA. RD Meinen, Y Alali, A Al‐Subu, M Wilhelm, R McAdams, D McCulley, and J Limjoco, McFarland, WI and Madison, WI. University of Wisconsin‐Madison Abstract 65 35 A RISK‐PREDICTIVE MODEL FOR THE DEVELOPMENT OF RETINOPATHY OF PREMATURITY USING BIRTH WEIGHT, GESTATIONAL AGE, AND NEWBORN SCREENING METABOLITES. AT Morgan‐Harris, EA Jasper, SP Oltman, RJ Baer, EE Rogers, JM Dagle, LL Jelliffe‐Pawlowski, and KK Ryckman, Iowa City, IA and San Francisco, CA. University of Iowa Hospitals and Clinics Abstract 66 36 A RIDE OF YOUR LIFE: SPONTANEOUS PNEUMOMEDIASTINUM IN AN ADOLESCENT FROM A ROLLER COASTER RIDE. D Nolan, and P Khandhar, Royal Oak, MI. Beaumont Children's Abstract 67 37 PERFORATED MECKEL’S DIVERTICULUM IN A NEONATE: CASE REPORT AND LITERATURE REVIEW. FO Orelaru, NS Reddy, and P Brahmamdam, Royal Oak, MI. Beaumont Children's Abstract 68 38 A 2 YEAR OLD CHILD WITH ECZEMA HERPETICUM. A Ozcan, K Kahale and D Nguyen, Royal Oak, MI. Beaumont Children's Abstract 69 39 SUDDEN ARM SWELLING IN A NEONATE. LR Pavlek, and E Braswell, Hilliard, OH and Columbus, OH. Nationwide Children's Hospital Abstract 70 40 A TEENAGER WITH SEVERE ANXIETY AND CHRONIC FECAL INCONTINENCE. A Porto, I Onwuzurike, K Levasseur, and M Menoch, Royal Oak, MI. Beaumont Children's Abstract 71 41 NOT JUST A DELTA WAVE: AN UNCOMMON DIAGNOSIS IN A PATIENT WITH WPW AND NEUROLOGIC EVENTS. A Prabhu, ME McCormick, and P Khandhar, Royal Oak, MI. Beaumont Children's Abstract 72 42 ROTAVIRUS VACCINATION AMONG NEONATES IN THE NEONATAL INTENSIVE CARE UNIT, HOW MANY ARE MISSED? CS Regan and PJ Sanchez, Dublin, OH and Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 73 43 VENTILATOR ASSOCIATED EVENTS IN THE NEONATAL INTENSIVE CARE UNIT: A DESCRIPTIVE COHORT, LESSONS LEARNED, AND OPPORTUNITIES FOR PREVENTION. KM Satrom, J Cramer, E Tinjum, D Brown, and S Gupta, Saint Paul, MN and Minneapolis, MN. University of Minnesota Abstract 74 44 PROPOFOL‐ASSOCIATED PRIAPISM IN A PREPUBESCENT PEDIATRIC PATIENT. C Savoie, V Rajanna and P Khandhar, Royal Oak, MI. Beaumont Children's Abstract 75 11
45 MINIMIZING LENGTH OF STAY IN HOSPITALIZATIONS FOR WELL APPEARING FEBRILE INFANTS. SE Sefcovic, S Smith, and M Mier, Chicago, IL. University of Illinois at Chicago Abstract 76 46 SURFACTANT FOR ACUTE PULMONARY HEMORRAGE IN A NEONATE. HN Shah, K Rosburg, E Anderson, J Jones, and E Bonachea, Gahanna, OH and Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 77 47 WHAT ROLE SHOULD SOCIAL MEDIA PLAY IN CLINICAL DECISION MAKING? HN Shah, Gahanna. Nationwide Children's Hospital/The Ohio State University Abstract 78 48 MATERNAL TRANSFERS IMPACT NEONATAL MORTALITY IN VERY PRETERM INFANTS. K Shah, RO deRegnier, and AC Bennett, Chicago, IL. Northwestern University Medical Center Abstract 79 49 VARIABILITY IN DIAGNOSTIC FLUOROSCOPY EVALUATION OF BOWEL OBSTRUCTION IN HOSPITALIZED INFANTS. ZS Shah, M Moallem, BD Kenney, DG Bates, and IK Gulati, Powell, OH and Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 80 50 VITAMIN D SCREENING IN CHILDREN & YOUNG ADULTS ‐ WHAT ARE WE DOING & WHAT SHOULD WE BE DOING? B Shannon, A Sawni, and J LaChance, Bloomfield Hills, MI and Flint, MI. Michigan State University Abstract 81 51 A 4 YEAR OLD CHILD WITH TENSION PNEUMOPERITONEUM. S Sonnamaker, A Porto and D Nguyen, Royal Oak, MI. Beaumont Children's Abstract 82 52 HISTOLOGICAL CHANGES OF BRONCHOPULMONARY DYSPLASIA AND PULMONARY HYPERTENSION: AN AUTOPSY SERIES OF 42 PRETERM INFANTS. A Stone, J Poulik, Y Xin, A Sharma, and BG Sood, Detroit, MI. Wayne State University Abstract 83 53 NUP155 REGULATES PLURIPOTENT MICRORNA EXPRESSION. EC Storm, CC Preston, TA Bradley, and RS Faustino, Sioux Falls, SD. University of South Dakota Abstract 84 54 THE INTESTINAL MICROBIOME OF THE LATE PRETERM INFANT IS ALTERED BY DIET AND ANTIBIOTIC USE. RA Vo, J White, Z Wang, X Wang, and S Marzano, Sioux Falls, SD and Brookings, SD. University of South Dakota Abstract 85 55 PRIMARY PULMONARY VEIN STENOSIS. L Walsh, B Rivera, C Mitchell, and C Backes, Columbus, OH. Nationwide Children's Hospital/The Ohio State University Abstract 86 12
56 MORAXELLA LACUNATA BACTEREMIA IN A TODDLER WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME TREATED WITH ECULIZUMAB: CASE REPORT AND LITERATURE REVIEW. P Bicoll, A Goyal, NB Blatt, and BJ Freij, Royal Oak, MI. Beaumont Children's Abstract 87 57 CHRONIC TESTICULAR TORSION IN A HEALTHY NEONATE. A Goyal and S Bassel, Royal Oak, MI. Beaumont Children's Abstract 88 58 PRENATAL DIAGNOSIS OF SMA WITH SUCCESSFUL INITIATION OF INTRA‐THECAL NUSINERSEN INDUCTION ON DAY 3 OF LIFE. E Son, G Kennady, and ME McCormick, Royal Oak, MI. Beaumont Children's Abstract 89 13
The James Sutherland Award The James Sutherland Award was named after a neonatologist from the University of Cincinnati, who was instrumental in establishing their neonatal unit. Dr. Sutherland was a renowned teacher, clinical investigator, and role model for trainees. He was active in the Midwest Society for Pediatric Research, and encouraged trainees to submit work at the annual meeting. The award, which recognizes the best investigative work presented by a junior faculty member, was first given in 1991. To be eligible for this award, the junior faculty candidate must be no more than five years out of fellowship training. The award is accompanied by an honorarium and plaque. The recipient is announced and honored each year at the Founder and Sutherland Awards Luncheon held during the MWSPR annual meeting. 1994 Thomas Scholz, MD 1995 Edward N. Guillery, MD 1996 Michael R. Uhing, MD 1997 Carol Gilmour, MD 1998 Robert H. Lane, MD 1999 I. I. Ekekezie, MD 2000 D. Balkundi, MD 2001 Janine Y. Khan, MD 2002 Steven Pipe, MD 2003 Shruti M. Phadke, MD 2004 J. Carter Ralphe, MD 2005 Michael Blake, MD, PhD 2006 Matthew I. Goldsmith, MD 2007 Jayme D. Allen, MD 2008 Alex Huang, MD and Mara Becker, MD, MSCE 2009 Michael Wilhelm, MD 2010 Celeste Morely, MD 2011 Amy VanMorlan, MD 2012 Juan Boriosi, MD 2013 Craig A. Byersdorfer, MD 2014 Naim Alkouri, MD 2015 Sarah Haskell, MD 2016 Dave McCulley, MD 2017 Jennifer Bermick, MD and David Gordon, MD 2018 Awarded at the MWSPR Meeting 14
The Frederic M. Kenny Memorial Award Frederic M. Kenny was instrumental in establishing the Pediatric Endocrinology Clinical and Fellowship Program at the Children’s Hospital in Pittsburgh. Dr. Kenny was a scholarship student at Princeton University, then a medical school student at The Johns Hopkins University School of Medicine, where he received his medical degree in 1955. He completed his general pediatric residency at The Johns Hopkins Hospital in 1958 and then spent two years in the U.S. Navy. He then returned to The Johns Hopkins Hospital where he completed a pediatric endocrine fellowship. In 1962, Dr. Kenny accepted an invitation to move to Pittsburgh and assume the position of director of the Pediatric Endocrine Division. He developed an outstanding clinical program in pediatric endocrinology and laboratory research focused primarily on normal adrenal function ranges for children and adolescents. He was intensely interested in the pathophysiology of all of the endocrinopathies, and his work led to the description of the course of endocrine diseases. He co‐authored approximately 100 papers and made more than 40 presentations at scientific meetings around the world. The Kenny Award is given for outstanding research presentation by a fellow at the MWSPR, and with sponsorship from Abbott Nutrition includes an honorarium and plaque. 1989 Michael S. (Mickey) Caplan, MD 1996 Brenda B. Poindexter, MD 2001 J. Carter Ralphe, MD 2002 Indra D. Chandrasekar, MD 2003 Heather Bartlett, MD 2004 Eyal Shteyer, MD 2005 Peter DeYoung, MD 2006 Rinku Mehra, MD 2007 Wendy Luce, MD 2008 Melissa Agoudemous, MD 2009 Suzanne Kingery, MD 2010 Misty Good, MD 2011 Andrew Harris, MD 2012 Brian Becknell, MD 2013 Brittany L. Knipstein, MD 2014 Jessica White, MD 2015 Kok‐Lim Kua, MD 2016 Rakhee Bowker, MD 2017 Stacy Kern, MD 2018 Awarded at the MWSPR Meeting 15
The Jack Metcoff Award The Jack Metcoff Award is given for outstanding research presentation by a resident or fellow at the MWSPR. The recipient receives a plaque and honorarium. Jack Metcoff made a major impact on the field of pediatric nephrology and body fluid physiology. Throughout his career, Dr. Metcoff was the consummate teacher of clinical pediatrics and pediatric nephrology, of a problem‐oriented approach to patient care, of the use of computers in medicine, and of investigative attitudes and techniques. The Annual Conference on the Kidney, which he edited from 1950 to 1967, reflected the best of basic and clinical research progress in those years and remains a hallmark of journalistic excellence. As a leader and catalyst in the development of the Nephrosis Foundation, which evolved into the National Kidney Foundation and the American Society of Nephrology, he helped to lay the foundation for current professional and patient education. 1994 Bindya S. Singh 1995 Genie E. Roosevelt 1996 Raghavendra Rao 1997 Howard M. Katzenstein 1998 Rajeev Dixit 1999 Jennifer L. Kloesz 2000 Gregory Dalshaug 2001 Lisa K. Kelly 2002 Nancy B. Aspey 2003 Gerhard C. Hildebrandt 2004 Aaron K. Olson 2005 Christopher Linblade 2006 Todd D. Nebesio 2007 Nicholas Von Bergen 2008 Sundan Rajan 2009 Paul Mann 2010 Shaun Ashfield 2011 Dennis Slagel 2012 Brian Stansfield 2013 Lauritz Meyer 2014 Sophia Patel 2015 Jean Dinh 2016 Kyle Sabey 2017 Katie Satrom, MD 2018 Awarded at the MWSPR Meeting 16
The William Segar Award The William Segar Award was initiated in 2012 to be given annually to a student, resident or fellow trainee with a hypothesis driven clinical research or behavioral/social or education project that involves innovative improvement in patient care delivery. Dr. Segar’s father was the first pediatrician to practice in the state of Indiana. Bill would earn both his BS (1944) and MD (1947) from Indiana University. Dr. Segar has long been an advocate for trainees and had served the MWSPR well as its 5th President and 2nd Founder’s Award winner. Dr. William E. Segar was one of the 38 people who attended the first meeting of the Midwest Society for Pediatric Research in Iowa City on October 27, 1959. He was present for the first business meeting and voted on the bylaws of the Society. He became the 5th president of the MWSPR in 1965. He was an active member and organizer of the Salt & Water Club, an active group that met adjacent to the MWSPR. Together with Dr. Malcolm Holliday, he developed Holliday‐Segar equation for calculating fluid therapy. Other than his time in the US Army at Walter Reed Medical Center, he trained and practiced medicine exclusively in Pediatric Departments within the MWSPR territory, University of Indiana, University of Illinois, Mayo Medical School, and finally the University of Wisconsin, where he became Chair of Pediatrics. This award is sponsored by Friends of William E. Segar. 2012 Carl Backes, MD 2013 Shawna S. Shafer, MD 2014 Emma Austenfeld 2015 Brock Medsker, MD 2016 David Segar, MD 2017 John Fiester, MD 2018 Awarded at the MWSPR Meeting 17
Cleveland Clinic Award The Cleveland Clinic awards Student Award is given for the most outstanding abstract presentation by a trainee at a level prior to postgraduate training or residency. The Cleveland Clinic has long supported the role of medical, graduate, undergraduate students, and even high school students in the MWSPR and provides ongoing support for this award. 2001 Anthony Ratanproeksa 2002 Liza Cadnapaphornchai 2003 Karen Wiseman 2004 Emily Segar 2005 Amy Hurst 2006 Christopher Lux 2007 Keri Drake 2008 Christa Pittner 2009 Katie Meyer 2010 Emily Peterson 2011 Jeremy Sandgren 2012 Brandon Downing 2013 Richard C. Godby 2014 Micaela Zywicki 2015 Raymond Kreienkamp 2016 Matthew Murtha 2017 Haley Bremer 2018 Awarded at the MWSPR Meeting 18
The Stanley Phillips Award Awarded for the best poster or posters at the MWSPR meeting. This award is named after Stanley Phillips III, a first year neonatology fellow at University of Wisconsin, who died during a transport in 2013 from a terrible ambulance accident. Dr. Phillips was a kind and compassionate physician, whom loved caring for ill newborns. He was looking forward to his research career and presenting at the MWSPR meeting. However, his research and clinical career was cut short. In the short time as a fellow, he was admired as an enthusiastic, inquisitive, thoughtful and caring physician. This award is sponsored by Meriter Foundation and University of Wisconsin Department of Pediatrics, Neonatology Division. 2013 Frances A. Boyle 2013 BreAnn Sheehan, MD 2014 Michael Thompson, MD 2015 Michael Thompson, MD 2016 Kristin Kan, MD, MPH 2017 June Hu, MD 2018 Awarded at the MWSPR Meeting 19
The Founder’s Award The Founder’s Award is the highest honor given by the Midwest Society for Pediatric Research to a senior member in recognition of contributions made in the development of the careers of academic pediatricians and in the advancement of pediatric research. Since 1986, this award has recognized some of the leaders in our field of pediatric research and academic medicine. Mead Johnson Nutritionals has generously provided an honorarium and plaque to the recipients during an awards luncheon held in honor of the recipient. 1986 Samuel J. Fomon, MD 1987 William E. Segar, MD 1988 Orville C. Green, MD 1989 Ira M. Rosenthal, MD 1990 Jean Holowach‐Thurston, MD 1991 William Weidman, MD 1992 Reginald D. Tsang, MD 1993 Rosita Pildes, MD 1994 Dharmapuir Vidyasagar, MD 1995 Fred G. Smith, MD 1996 Gunner B. Stickler, MD 1997 Dorothy J. Becker, M.B.B.Ch. 1998 Laurence A. Boxer, MD 1999 Robert T. Hall, MD 2000 Sherin U. Devaskar, MD 2001 Edward S. Ogata, MD 2002 Jean E. Robillard, MD 2003 Frank R. Greer, MD 2004 Robert P. Kelch, MD 2005 John A. Widness, MD 2006 James E. Heubi, MD 2007 Edward F. Bell, MD 2008 William E. Truog, MD 2009 Avory A. Fanaroff, MD 2010 Michael K. Georgieff, MD 2011 Juan F. Sotos, MD 2012 Alan H. Jobe, MD, PhD 2013 Howard Kilbride, MD 2014 Margaret K. Hostetter, MD 2015 Jeffrey Segar, MD 2016 Francis Sessions Cole, III, MD 2017 Valerie Opipari, MD 2018 Scott C. Denne, MD 20
MIDWEST SOCIETY FOR PEDIATRIC RESEARCH, INC. Officers and Council Members 2018 President Laura S. Haneline, MD (2018-2019) University of Iowa Children’s Hospital Past President Jeffrey Segar, MD (2017-2018) University of Iowa Children’s Hospital President-Elect Neal Blatt, MD, PhD (2018-2019) Beaumont Children’s Secretary Carl Backes, MD (2018-2022) Nationwide Children's Hospital Treasurer Noah Hillman, MD (2016-2020) Cardinal Glennon Children's Hospital Council Members (three-year term) Craig Garfield, MD (2019) Steve McElroy (2020) Northwestern University University of Iowa Hospital and Clinic Lyndsay Harshman, MD (2020) Ulrike Mietzsch, MD (2020) University of Iowa Hospital and Clinic Indiana University Sarah Haskell, DO (2018) Steven Olsen, MD (2018) University of Iowa Hospital and Clinic Children’s Mercy Kansas City Ben Kopp, MD (2020) Sara Ramel, MD (2019) Nationwide Children's Hospital University of Minnesota David McCulley, MD (2019) University of Wisconsin 21
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