Pharmaceutical & Biotechnology Sector: 2021 Report V.E, AN AFFILIATE OF MOODY'S - Vigeo Eiris
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V.E– Sector Report J AN U ARY 2 02 1 188 companies in the sector Pharmaceutical & Biotechnology Sector: 2021 Report V.E, AN AFFILIATE OF MOODY’S
ESG Sector Report Outline Key findings 2021 …………………………………………………………………………………………………………….. 04 Sector context ………………………………………………………………………………………………………………….. 06 Sector performances and trends ……………………………………………………………………………………………. 07 Sector performance and rankings ………………………………………………………………………………………….. 10 To access the full report, please contact investorcustomer.service@vigeo-eiris.com Head of ESG Research: Cristina Daverio cristina.daverio@vigeo-eiris.com +39 02 27727141 Research manager: Zineb Raji Zineb.Raji@vigeo-eiris.com Sector expert: Fatima-Ezzahra Zouita Sector analysts: Aida Jorquera Oumaima Doukkane Chong-Ren Jian Oumayma Oummouch Fatima-Ezzahra Zouita Salima Bouchama Faustine Sourdin Salima Kabbaj Giannina Salvo Sarah Cherrat Lauren Boulie Sarra El Hakour Nada Snoussi Soumaya Najib
ESG Sector Report ABOUT THIS REPORT Companies considered in this report belong to the following geographical zones: Asia Pacific, North America, Europe, Emerging Market. Currently, V.E Equitics research covers around 4,800 issuers divided into 39 sectors. Periods considered: Current data: To compute average performances, we consider data from the latest review of each company covered in the report within the last 24 months as of the last day of the month prior to the sector report publication (e.g. 31/05/2020 for a report released in June 2020) Historical data: To compute average performances, we consider data from the latest review of each company covered in the report rated within the last 24 months preceding the last day of [year - 1 month] before the sector report publication (e.g. 31/05/2018 and 31/05/2017 for a report released in June 2019) Sector data: For each company of the sector, data considered in average calculations, we take data from latest Rating, Rating-1 and Rating-2, excluding outdated publications (which have been adjusted by errata or updated through alerts). Universe data: We take into account all latest delivered information and companies on the day we extract data. Rankings: Sector rankings are computed as of 31/12 of each fiscal year. Percentages: Figures included in this report have been rounded up or down automatically and therefore may not add up to 100%. ABOUT V.E V.E is an independent international provider of environmental, social and governance (ESG) research and services for investors and public and private organisations. We undertake risk assessments and evaluate the level of integration of sustainability factors within the strategy and operations of organisations. V.E offers a wide range of services: − For investors: decision-making support covering all sustainable and ethical investment approaches (including ratings, databases, sector analyses, portfolio analyses, structured products, indices and more). − For companies and organisations: supporting the integration of ESG criteria into business functions and strategic operations (including sustainable bonds, corporate ratings, CSR evaluations and more). V.E obtained ISO 9001: 2015 certification for its processes relating to methodology, rating, sale and delivery of its data to all types of investors. With a team of more than 240 experts of 28 different nationalities, V.E is present in Paris, London, Brussels, Casablanca, Hong Kong, Milan, New York, Rabat and Santiago. The V.E Global Network, comprising 4 exclusive research partners, is present in Brazil, Germany, Israel and Japan. For more information: www.vigeo-eiris.com Pharmaceutical & Biotechnology – January 2021 2
ESG Sector Report KEY FINDINGS 2021– PHARMACEUTICAL & BIOTECHNOLOGY SECTOR Sector average performance Top performers Universe average 10 33 62 performance Europe: GlaxoSmithkline (62/100) 29 North America: Johnson & Johnson (53/100) Sector minimum and maximum Asia Pacific: Takeda Pharmaceutical (51/100) 0 100 Emerging Markets: Aspen Pharmacare Holdings ; Dr Reddy’s ESG Performances – Sector & Universe Laboratories (56/100) Environment Environment 21 29 Most improved since 2018 Europe: Grifols; Genfit (+11) 31 North America: Alkermes (+5) Social Social 29 Asia Pacific: Kissei Pharmaceutical (+15) Governance 40 Emerging Markets: Hanmi Pharmaceutical (+14) Governance 36 Domain performances– Sector & Universe 0 100 Most material drivers 44 ADVANCED Corporate Corporate Governance 42 (60-100) Governance 34 ROBUST Business Business Behaviour 31 (50-59) Behaviour 31 • Board of directors Community Community Involvement 25 • Information to patients Involvement LIMITED • Corruption • 26 (30-49) Fundamental human rights HumanHuman Resources 23 Resources • Product safety 37 • Anti-competitive practices Human Rights Human Rights 34 • Sustainable healthcare systems 29 • Career management Environment • Environment 21 WEAK Accidental pollution (0-29) • Responsible lobbying • Access to medicines and societal impacts of products Risk Mitigation – Sector & Universe 10 35 69 Reputation Reputation 29 29 56 Carbon footprint 7 Share of companies in each level of carbon footprint Human Capital Human Capital 26 Moderate Significant High Intense 4 35 71 Operational Operational Sector (%) 71 25 4 EfficiencyEfficiency 31 Universe (%) 53 29 13 5 12 35 73 Legal Security Legal Security 34 Energy transition Share of companies in each level of energy transition performance 0 100 Takeaways Sector (%) Weak Limited 73 Robust Advanced 15 7 4 Can voluntary licensing agreements and waiver of rights by patent right Universe (%) 61 26 7 5 holders help to increase access to medicines during a pandemic? Covid-19: an urgent call to put business ethics before profit Sustainable goods & services Share of companies in each level of involvement in goods and services contributing to Despite slight improvement, the sector continues to demonstrate a limited sustainable development approach to product safety Pharmaceutical & biotechnology companies and animal testing: an ongoing None Minor Significant Major debate Sector (%) 3 6 3 88 Responsible marketing tactics and proper information to customers are still Universe (%) 36 48 5 11 a major challenge Controversies risk mitigation Share of companies in each performance level in terms of controversy risk management Number of companies in Weak Limited Robust Advanced No controversies Warning list : 9 10 16 2 72 Pharmaceutical & Biotechnology – January 2021 3
ESG Sector Report SECTOR CONTEXT Sector overview Number of companies V.E’s Pharmaceuticals and Biotechnology sector is composed of 188 companies. These companies are engaged in the research, development, manufacturing, and Sector 188 distribution of drugs for human or veterinary use. The medicines produced are aimed to cure or manage diseases, or to prevent infection. Europe 59 The industry’s value chain starts with the manufacturing of medicines, which involves North America 60 research and development in addition to regulatory approval. The second phase includes the distribution and handling of medicines from the manufacturer to the end Asia-Pacific 40 user (through retail, pharmacy, hospital, or dispensing doctors). The final step in the value chain is the commercialisation and the provision of the right medicine dosage, Emerging Market 29 form, and advice to the right patient. Companies inclusions in V.E – Euronext Indices World 120 Europe 120 Eurozone 120 US 50 France 20 UK 20 Benelux 20 Takeda GlaxoSmithkline Grifols Merck & Company NA GlaxoSmithkline NA Pharmaceutical Merck & Company Novozymes Amgen Amgen Grifols Abbott Laboratories Bristol Myers Squibb Subsector description The Pharmaceuticals and Biotechnology sector is composed of two broad sub-sectors: biotechnology companies and traditional pharmaceuticals. The primary difference between the two is the method by which they produce drugs: - Pharmaceutical companies manufacture drugs through a series of chemical synthesis. Based on their size and strategy, pharmaceutical companies may conduct extensive in-house research or seek to license drugs from other pharmaceutical or biotechnology companies. Some pharmaceutical companies are considered as specialty pharma since they focus on specific activities such as R&D only or marketing and sales only. Pharmaceutical companies generally hold the exclusive rights to manufacture and distribute their drugs for five years. - Biotechnology companies produce drugs with a biological basis that are manufactured in living organisms such as bacteria or enzymes. These companies are working to duplicate or change the function of a living cell and could use genetics research to develop products for human diseases and conditions. Biotechnology companies hold their patents for 12 years. Pharmaceutical & Biotechnology – January 2021 4
ESG Sector Report Sector reporting rates Data displayed below reflects the evolution over the past three years of the average rate of ESG indicators analysed by V.E that companies report against, with notably: Spread per geographical area Spread per materiality of ESG drivers analysed for the sector In January 2021, the reporting rate of V.E’s global universe stood at 65%. 100 Most material ESG drivers - Weighted at 3 90 100 69 2018/12 80 58 60 70 2019/12 60 0 2020/12 50 Highly material ESG drivers - Weighted at 2 40 2018/12 100 2018/12 51 53 61 30 2019/12 2019/12 20 2020/12 0 2020/12 10 0 Material ESG drivers - Weighted at 1 100 2018/12 55 38 36 2019/12 0 2020/12 Pharmaceutical & Biotechnology – January 2021 5
ESG Sector Report SECTOR PERFORMANCES AND TRENDS Impacts Sector involvement in products and services considered sustainable given their positive impact on social and environmental issues Sector Universe 3% 6% 3% Major 11% Major 5% Significant 36% Significant Minor Minor None None 88% 48% The involvement in sustainable products and services of companies in this industry is high overall compared to the whole V.E universe. Out of all companies covered by V.E’s research in the Pharmaceuticals and Biotechnology sector, 97% display involvement in sustainable products and services, with the majority (88%) displaying major involvement. The involvement relates to 24 different activities that address sustainable development challenges, notably pharmaceuticals, pharmaceutical materials and medical technology that together represent more than three quarters of the industry’s involvement. Case study: H Lundbeck displays one of the highest levels of involvement (100%) in products and services contributing to sustainable development addressing the theme Health. Pharmaceuticals: Lundbeck produces pharmaceuticals for the treatment of psychiatric and neurological disorders, including depression, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's disease, epilepsy, alcohol dependence, and insomnia. Its key products are notably Rexulti (depression and schizophrenia), Brintellix (depression), Abilify Maintena (schizophrenia), Northera and Onfi (epilepsy). All of the Company's revenue is derived from the sale of pharmaceuticals. Pharmaceutical & Biotechnology – January 2021 6
ESG Sector Report Sustainable Development Goals V.E assesses the contribution of companies to the achievement of sustainable development goals (SDGs) through their behaviours and products/services. Pharmaceuticals & Biotechnology Universe 4% 5% 6% 5% Highly Positive Highly Positive 23% 19% Positive 25% Positive Marginal Marginal Adverse Adverse 68% 45% Highly Adverse Highly Adverse Almost a quarter of companies in the Pharmaceuticals and Biotechnology sector have a highly positive contribution to the SDGs Those companies combine an ESG performance above geographical peers, a relevant sustainable offering, face no critical controversies and are not involved in controversial activities. The sector’s contribution is aligned with the total positive contribution of all sectors in the V.E’s ratings universe. Most companies in the sector have only marginal contributions to SDGs, with the remaining 9% having adverse to highly adverse contributions. The sector’s adverse to highly adverse contributions are lower than the 31% combined contribution of all sectors in the V.E’s ratings universe. On one hand, the sector has a poor record in terms of social welfare - 43% percent of the companies display a combined adverse to highly adverse impact, while 42% have only a marginal contribution. On the other hand, almost all companies in the sector display positive to highly positive contributions to enabling healthy lives due to the offer of pharmaceuticals, pharmaceutical materials and medical equipment. Carbon footprint and energy transition Energy Transition performance Sector (/100) Universe (/100) Energy transition score Weak - 19 Weak - 26 Energy transition: Top performers GlaxoSmithkline (73/100) Novo Nordisk (68/100) Roche Holding (66/100) Sanofi (66/100) Pharmaceutical & Biotechnology – January 2021 7
ESG Sector Report Charts below display the share of companies within each range of carbon footprint and energy transition performance. Carbon footprint Energy Transition performance Global 71 25 4 Sector (%) 73 15 7 4 53 29 13 5 Universe (%) 61 26 7 5 Europe 78 19 3 Sector (%) 71 14 7 8 64 23 9 3 Universe (%) 49 29 11 11 North America 73 18 8 Sector (%) 78 10 7 5 46 32 16 6 Universe (%) 69 23 52 Asia Pacific Sector (%) 78 23 55 33 13 Universe (%) 55 30 11 3 64 28 53 Emerging Market Sector (%) 45 55 93 7 Universe (%) 39 34 17 9 69 25 52 Moderate Significant High Intense Weak Limited Robust Advanced At first sight, the Pharmaceuticals and Biotechnology sector is not a particularly high greenhouse gas (GHG) emitting sector, as indicated by the 71% of the companies in the sector having a moderate carbon footprint. However, given the size of the global workforce and the energy needed for chemical processes, heating and cooling, as well as for product transportation, the operations in this sector can be very carbon intensive and be even dirtier than automotive production operations1. The management of energy consumption and the impacts generated from transportation are the main aspects on which companies in this sector can work to reduce their GHG emissions and successfully transition to a low carbon economy. Yet, the sector’s average performance in regard to both aspects is weak, standing at 28/100 for the topic of Minimising environmental impacts from energy use (ENV 2.2), and 10/100 for the topic of Management of environmental impacts from transportation (ENV 2.7). Over the last two years, these scores have improved by only 2.5 and 1 points for ENV2.2 and ENV 2.7, respectively. To enhance their performance for energy efficiency and emission reductions, companies from this sector can upgrade their equipment, switch to alternative fuels, and use state of the art technologies to produce renewable energies. Concerning transportation, companies can improve by taking steps to reduce the emissions related to the transport of their personnel. They can also rationalise product transport flows, and make contractual commitments with transport logistic firms to encourage the mitigation of negative impacts from transportation. Overall, the sector demonstrates a weak energy transition performance with an average score of 19/100. Since 2019, this score has increased by only one point. This leads to a low level of assurance on the sector’s response and capacity to manage the risks and opportunities associated with the transition to a low-carbon economy. Social Impacts and Value Creation Social impacts - Key Indicators Sector (%) Universe (%) 1 Belkhir, L., & Elmeligi, A. (2019). Carbon footprint of the global pharmaceutical industry and relative impact of its major players. Journal of Cleaner Production, 214, 185-194. Pharmaceutical & Biotechnology – January 2021 8
ESG Sector Report Percentage of women in management 21.7 21.5 Share of companies for which we have no information 0.0 0.4 Share of companies with operations in OFCs or jurisdictions considered by the OECD as 53.2 53.9 not compliant enough with tax transparency rules Share of companies without operations in such jurisdictions 31.4 38.9 Share of companies for which we have no information 15.4 7.3 Share of companies signatory to the Global Compact 21.1 24.2 Value Creation & Sharing Sector (%) Universe (%) Share of companies transparent on their R&D investments 95.7 39.8 Share of companies transparent on the share of added value received by employees 70.7 68.3 relative to shareholders Share of companies for which executive variable remuneration is linked to CSR 8.4 21.3 objectives Share of companies with comprehensive transparency on taxes2 1.6 5.8 Share of companies with significant transparency on taxes3 22.2 38.2 Share of companies with partial transparency on taxes4 18.9 15.2 Share of companies with insufficient transparency on taxes5 54.6 38.0 Share of companies for which we have no information on taxes 2.7 2.8 2 In addition to geographical information on taxes paid, sales, operating profit or number of employees, these companies declare the difference between statutory tax rates and the rate actually paid. 3 These companies report on sales, and/or operating profit, and/ or number of employees per operating region and disclose taxes paid by country or region. 4 These companies’ reporting focuses on taxes paid in countries or regions representing more than 50% of their operations. 5 These companies report only on gross taxes paid, with no breakdown by region or country. Pharmaceutical & Biotechnology – January 2021 9
ESG Sector Report SECTOR PERFORMANCE AND RANKING Position of sector versus Universe Average score Current rank Previous rank Universe 33.4 Development Banks 56.9 1 1 Diversified Banks 48.1 2 2 Specific Purpose Banks & Agencies 46.7 3 3 Waste & Water Utilities 42.2 4 4 Forest Products & Paper 41.5 5 5 Electric & Gas Utilities 40.3 6 7 Luxury Goods & Cosmetics 39.7 7 6 Chemicals 38.1 8 10 Mining & Metals 37.5 9 12 Telecommunications 37.0 10 8 Energy 36.8 11 11 Publishing 36.4 12 9 Building Materials 34.9 13 17 Oil Equipment & Services 34.8 14 14 Retail & Specialised Banks 34.8 15 16 Home Construction 34.6 16 13 Business Support Services 34.6 17 22 Beverage 34.1 18 15 Automobiles 33.5 19 19 Heavy Construction 33.4 20 20 Technology-Hardware 33.0 21 18 Transport & Logistics 33.0 22 25 Travel & Tourism 32.7 23 26 Insurance 32.7 24 24 Financial Services - Real Estate 32.2 25 30 Broadcasting & Advertising 32.0 26 23 Mechanical Components & Equipment 31.7 27 32 Supermarkets 31.6 28 27 Industrial Goods & Services 31.5 29 29 Health Care Equipment & Services 31.4 30 34 Electric Components & Equipment 31.0 31 28 Aerospace 30.8 32 21 Financial Services - General 30.7 33 33 Food 29.3 34 37 Hotel, Leisure Goods & Services 29.2 35 36 Software & IT Services 29.0 36 35 Pharmaceuticals & Biotechnology 28.9 37 38 Tobacco 28.9 38 31 Specialised Retail 27.2 39 39 Pharmaceutical & Biotechnology – January 2021 10
ESG Sector Report Performance trends – Global level and per zone 100 Sector Europe North America Sector performances distribution 80 1% 33 31 33 28 28 28 6% 60 Weak (0-29) 28% Limited (30-49) 40 27 27 29 Robust (50-59) Asia Pacific Emerging Market 65% 20 Advanced (60-100) 23 26 29 21 20 23 0 Sector performances distribution Weak (0-29) Limited (30-49) Robust (50-59) Advanced (60-100) Sector standard deviation: 10.25 0 10 20 30 40 50 60 70 80 90 100 Share of companies within each performance level range The Pharmaceuticals and Biotechnology sector displays a weak overall CSR performance, which is stable compared to the previous review. Sector leaders are concentrated in Europe, with an average performance of 33/100, whilst laggards are mostly listed in the Emerging Markets region (average performance of 23/100). European companies display a relatively higher level of transparency on commitments to CSR issues, as demonstrated by an average overall score of 34/100 on the leadership pillar compared to only 21/100 for Emerging Markets. When it comes to the implementation pillar, European companies are more communicative on measures, with a score of 26/100 compared to 17/100 in Emerging Markets. Moreover, European companies report more on KPIs of different CSR issues under review as illustrated by an average overall score of 38/100 on the results pillar compared to 32/100 in Emerging Markets. 65% of companies display weak performances, 28% display limited performances and 6% achieve robust performances, while only one company achieves an advanced performance. Companies’ performances are relatively heterogeneous as illustrated by the 10.25 standard deviation and the scattering of performances. GlaxoSmithkline is the leader in the sector with a global performance of 62/100. The company accomplishes the highest score on the Corporate Governance (74/100) and Community Involvement (68/100) domains with advanced scores. An equally advanced performance of 65/100 is achieved in the Human Rights and Environment domains and a robust score is obtained in the Human Resources (56/100) and Business Behaviour (55/100) domains. These distinguished performances are made possible thanks to reporting on comprehensive policies, measures and KPIs. This is in addition to demonstrating increased understanding and appropriate integration of CSR challenges that are at stakes for the company’s operations at governance level. Pharmaceutical & Biotechnology – January 2021 11
ESG Sector Report Management profile Average performances on the three pillars of CSR assessment Policies Implementation Results 100 100 100 80 80 80 60 60 60 40 Sector 40 Sector 40 Sector 20 Universe 20 Universe 20 Universe 0 0 0 Risk mitigation for strategic assets Overall, the Pharmaceuticals and Biotechnology sector stands below the average of the universe’s performance for management of risk factors which impact reputation, human capital, operational efficiency, and legal security. ESG risk mitigation scores are weak in relation to reputation (29/100) and human capital (26/100) and limited in relation to operational efficiency (31/100) as well as legal security (34/100). The area of human capital achieves the lowest score as the reported policies and efforts to manage employee-related impacts (such as the respect and promotion of fundamental labour rights, health and safety, impact of reorganisations and the management of layoffs, and career development) generally lack substantial and consistent disclosure across the majority of companies. Although still limited, the highest score is achieved in the area of legal security. The industry is highly regulated and under significant stakeholder scrutiny, with related exposure to legal and regulatory risks, companies seem more invested and mobilized to monitor and enhance their internal controls and processes to compliance in response to heightened transparency expectations and potential controversies. While many controversies are observed within the Pharmaceuticals and Biotechnology sector, companies are generally considered to be reactive on them. However, proactive management and corrective measures are not demonstrated, leading to a limited overall score for the sector’s performance on legal security risk management. 10 35 69 Sector average performance Reputation 29 Universe average 7 29 56 performance Human Capital 26 Sector minimum 4 35 71 and maximum Operational Efficiency 31 12 35 73 Legal Security 34 0 100 Pharmaceutical & Biotechnology – January 2021 12
ESG Sector Report Materiality: weighing & performances assessment V.E Methodology for the Pharmaceuticals & Biotechnology sector has remained unchanged since its previous review. ADVANCED (60-100) STRENGTHS ROBUST (50-59) • Board of directors • Shareholders • Information to patients • Audit & internal controls LIMITED (30-49) • Corruption • Non-discrimination and diversity • Fundamental human rights • Environmental strategy • Product safety • Executive remuneration • Anti-competitive practices • Energy • Health and safety • Fundamental labour rights • Social standards in the supply chain • Sustainable healthcare systems • Environmental standards in the supply • Career management • WEAK (0-29) chain Accidental pollution WEAKNESSES • Water • Responsible lobbying • Animal testing and biodiversity protection • Access to medicines and societal impacts of • Reorganisation products • Use and disposal of products • Atmospheric emissions • Transportation 1 2 3 MATERIALITY OF THE RISK FACTORS Pharmaceutical & Biotechnology – January 2021 13
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