Measles and rubella monthly update- WHO European Region - Vaccine-preventable Diseases and Immunization Division of Country Health Programmes

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Measles and rubella monthly update- WHO European Region - Vaccine-preventable Diseases and Immunization Division of Country Health Programmes
Measles and rubella monthly update—
WHO European Region

Vaccine-preventable Diseases and Immunization
Division of Country Health Programmes
Data as of 02 March 2023
Measles and rubella monthly update- WHO European Region - Vaccine-preventable Diseases and Immunization Division of Country Health Programmes
Measles
Updates including 2023

                         2
Measles and rubella monthly update- WHO European Region - Vaccine-preventable Diseases and Immunization Division of Country Health Programmes
Measles cases—WHO European Region,
February 2022–January 2023

                                                                                                                                                                                                       Top 10 countries
                                                                                                                                                                                               Country                             Cases
                                                                                                                                                                                                      Tajikistan                               513
                                                                                                                                                                                                         Türkiye                               286
                                                                                                                                                                                     Russian Federation                                        233
                                                                                                                                                                                           United Kingdom                                        56
                                                                                                                                                                                                         Poland                                  25
                                                                                                                                                                                                   Kyrgyzstan                                    24
                                                                                                                                                                                                          Serbia                                 24
                                                                                                                                                                                                         France                                  22
                                                                                                                                                                                                              Italy                              18
                                                                                                                                                                                                       Belgium                                   17
                                                                                                                                                                                   30 (57%) countries reported measles cases in the rolling 12-months.

Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there November not yet be full agreement. © WHO 2023. All rights reserved.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                         3
Measles and rubella monthly update- WHO European Region - Vaccine-preventable Diseases and Immunization Division of Country Health Programmes
Measles incidence per million population—
WHO European Region, February 2022–January 2023

                                                                                                                                                                                               Top 10 countries
                                                                                                                                                                                 Country                          Cases             Incidence
                                                                                                                                                                                            Tajikistan                  513                 51.54
                                                                                                                                                                                         Kyrgyzstan                       24                  3.62
                                                                                                                                                                                              Georgia                     13                  3.47
                                                                                                                                                                                               Türkiye                  286                   3.35
                                                                                                                                                                                                 Serbia                   24                  3.32
                                                                                                                                                                    Bosnia and Herzegovina                                  6                 1.86
                                                                                                                                                                            Russian Federation                          233                   1.61
                                                                                                                                                                                              Belgium                     17                  1.46
                                                                                                                                                                                 United Kingdom                           56                  0.83
                                                                                                                                                                                                Poland                    25                  0.63

Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there November not yet be full agreement. © WHO 2023. All rights reserved.

Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2022 revision.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                         4
Ten countries with the highest numbers of measles cases—
WHO European Region, February 2022–January 2023

                      Tajikistan                                                                                                                              513

                         Türkiye                                                                                         286

       Russian Federation                                                                                 233

            United Kingdom                               56

                         Poland                25

                   Kyrgyzstan                  24
                                                                                                Out of 1309 measles cases reported for February 2022 to
                          Serbia               24
                                                                                                January 2023, 1218 (93%) cases were reported by these 10
                         France                22                                               countries.
                              Italy          18

                        Belgium              17

                                      0                               100                   200                          300                      400   500         600
                                                                                                               Number of cases

30 (57%) countries reported measles cases in the rolling 12-months.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                           5
Measles cases by month—WHO European Region,
2021–January 2023

                            450

                            400

                            350
          Number of cases

                            300

                            250

                            200

                            150

                            100

                            50

                             0

                                                                                                           Oct

                                                                                                                 Nov

                                                                                                                       Dec

                                                                                                                                                                                      Oct

                                                                                                                                                                                            Nov

                                                                                                                                                                                                  Dec
                                          Feb

                                                                                                                                    Feb
                                  Jan

                                                                                                                                                              Jun
                                                                   May

                                                                            Jun

                                                                                                                             Jan

                                                                                                                                                        May

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                                                  Mar

                                                                                    Jul

                                                                                                     Sep

                                                                                                                                            Mar

                                                                                                                                                                          Aug

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                                                           Apr

                                                                                             Aug

                                                                                                                                                  Apr

                                                                                                                                                                    Jul
                                                                             2021                                                                               2022                                  2023
                                                                                                                                                                                                      2023
                                                                           (n=159)                                                                            (n=937)                               (n=405)
                                                                                                                                                                                                    (n=405)
                                                                                                                              Month
                                                                                          Lab confirmed                      Epi linked                 Clinically compatible

Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                               6
Number of sequences reported

                                                                                                                                                        10
                                                                                                                                                              20
                                                                                                                                                                    30
                                                                                                                                                                          40
                                                                                                                                                                                50
                                                                                                                                                                                       60

                                                                                                                                                   0
                                                                                                                                                    5
                                                                                                                                                    6
                                                                                                                                                    7
                                                                                                                                                    8
                                                                                                                                                    9
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                                                                                                                                                   11
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                                                                                                                                                   26
                                                                                                                                                   27
                                                                                                                                                   28

                                                                                                                                            2020
                                                                                                                                                   29
                                                                                                                                                   30

                                                                                                                                     2020
                                                                                                                                                   31
                                                                                                                                                   32
                                                                                                                                                   33
                                                                                                                                                   34
                                                                                                                                                   35
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                                                                                                                                                   52
                                                                                                                                                    1
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                                                                                                                                                   10

Data source: WHO measles nucleotide surveillance online database (MeaNS) data as of 02 March 2023
                                                                                                                                                   11
                                                                                                                                                   12
                                                                                                                                                   13

                                                                                                    B3
                                                                                                                                                   14
                                                                                                                                                   15
                                                                                                                                                   16
                                                                                                                                                   17
                                                                                                                                                   18
                                                                                                                                                   19
                                                                                                                                                   20
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                                                                                                                                                   25
                                                                                                                                                   26
                                                                                                                                            2021

                                                                                                                                                   27
                                                                                                                                                   28
                                                                                                                                     2021

                                                                                                                                                   29
                                                                                                                                                   30
                                                                                                                                                   31
                                                                                                                                                   32
                                                                                                                                                   33
                                                                                                                                                   34
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                                                                                                                                                   44
                                                                                                                                                   45
                                                                                                    D8

                                                                                                                                                   46
                                                                                                                                                   47
                                                                                                                                                   48
                                                                                                                                                   49
                                                                                                         Week of sample collection

                                                                                                                                                   50
                                                                                                                                                   51
                                                                                                                                                                                            Measles genotypes by week of sample collection—

                                                                                                                                                   52
                                                                                                                                                    1
                                                                                                                                                    2
                                                                                                                                                    3
                                                                                                                                                                                            WHO European Region, week 5, 2020 to week 4, 2023

                                                                                                                                                    4
                                                                                                                                                    5
                                                                                                                                                    6
                                                                                                                                                    7
                                                                                                                                                    8
                                                                                                                                                    9
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                                                                                                                                                   23
                                                                                                                                                   24
                                                                                                                                                   25
                                                                                                                                                   26
                                                                                                                                            2022

                                                                                                                                                   27
                                                                                                                                                   28
                                                                                                                                                   29
                                                                                                                                     2022

                                                                                                                                                   30
                                                                                                                                                   31
                                                                                                                                                   32
                                                                                                                                                   33
                                                                                                                                                   34
                                                                                                                                                   35
                                                                                                                                                   36
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                                                                                                                                                   50
                                                                                                                                                   51
                                                                                                                                                   52
                                                                                                                                                    1
                                                                                                                                                    2
                                                                                                                                            2023

                                                                                                                                                    3
                                                                                                                                     2023

                                                                                                                                                    4
                                             7
Measles
Latest update for 2022

                         8
Measles cases—WHO European Region, 2022

                                                                                                                                                                                                        Top 10 countries
                                                                                                                                                                                                    Country                             Cases
                                                                                                                                                                                                                 Tajikistan                     455
                                                                                                                                                                                                                    Türkiye                     126
                                                                                                                                                                                                Russian Federation                              114
                                                                                                                                                                                                      United Kingdom                              52
                                                                                                                                                                                                                    Poland                        27
                                                                                                                                                                                                              Kyrgyzstan                          23
                                                                                                                                                                                                                    France                        19
                                                                                                                                                                                                                         Italy                    18
                                                                                                                                                                                                                   Belgium                        17
                                                                                                                                                                                                                 Germany                          15
                                                                                                                                                                                      28 (53%) countries reported measles cases for 2022.

Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there November not yet be full agreement. © WHO 2023. All rights reserved.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                         9
Measles incidence per million population—
WHO European Region, 2022

                                                                                                                                                                                            Top 10 countries
                                                                                                                                                                               Country                            Cases             Incidence
                                                                                                                                                                                            Tajikistan                  455                 45.72
                                                                                                                                                                                         Kyrgyzstan                       23                  3.47
                                                                                                                                                                                              Georgia                     12                  3.20
                                                                                                                                                                    Bosnia and Herzegovina                                  6                 1.86
                                                                                                                                                                                               Türkiye                  126                   1.48
                                                                                                                                                                                              Belgium                     17                  1.46
                                                                                                                                                                            Russian Federation                          114                   0.79
                                                                                                                                                                                 United Kingdom                           52                  0.77
                                                                                                                                                                                                Poland                    27                  0.68
                                                                                                                                                                                             Romania                        9                 0.46

Disclaimer: The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city
or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there November not yet be full agreement. © WHO 2023. All rights reserved.

Population source: United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2022 revision.
Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                         10
Ten countries with the highest numbers of measles cases—
WHO European Region, 2022

                    Tajikistan                                                                                                                                  455

                       Türkiye                                                   126

      Russian Federation                                                     114

           United Kingdom                              52

                        Poland                  27
                                                                                                              Out of 937 measles cases reported for 2022, 866 (92%)
                  Kyrgyzstan                  23                                                              cases were reported by these 10 countries.
                        France               19

                            Italy           18

                      Belgium               17

                    Germany                15

                                    0                 50            100               150               200               250               300   350   400   450     500
                                                                                                               Number of cases

28 (53%) countries reported measles cases for 2022.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                             11
Measles cases by month—WHO European Region,
2020–2022

                            4500

                            4000

                            3500
          Number of cases

                            3000

                            2500

                            2000

                            1500

                            1000

                             500

                               0
                                                                                               Nov
                                                                                                     Dec

                                                                                                                                                                  Oct
                                                                                                                                                                        Nov
                                                                                                                                                                              Dec

                                                                                                                                                                                                                                           Oct
                                                                                                                                                                                                                                                 Nov
                                                                                         Oct

                                                                                                                                                                                                                                                       Dec
                                         Feb

                                                                                                                 Feb

                                                                                                                                                                                          Feb
                                   Jan

                                                                                                           Jan

                                                                                                                                                                                    Jan
                                                           May

                                                                                                                                   May

                                                                                                                                                                                                            May
                                               Mar

                                                                 Jun

                                                                                                                                          Jun

                                                                                                                                                                                                                   Jun
                                                     Apr

                                                                       Jul

                                                                                                                       Mar

                                                                                                                                                Jul

                                                                                                                                                            Sep

                                                                                                                                                                                                Mar

                                                                                                                                                                                                                         Jul
                                                                                                                                                                                                                               Aug
                                                                                                                                                                                                                                     Sep
                                                                             Aug
                                                                                   Sep

                                                                                                                             Apr

                                                                                                                                                      Aug

                                                                                                                                                                                                      Apr
                                                               2020                                                                        2021                                                                     2022
                                                            (n=12204)                                                                    (n=159)                                                                  (n=937)
                                                                                                                                                Month
                                                                                               Lab confirmed                               Epi linked                          Clinically compatible

Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                        12
Measles cases and incidence by age group* and vaccination
status—WHO European Region, 2022

                            350                                                                                                                                                    20.00

                                                                                                                                                                                           Incidence per million population
                                    18.12
                                                                                                                                                                                   18.00
                            300
                                                                                                                                                                                   16.00
          Number of cases

                            250                                                                                                                                                    14.00
                                                                                                                                                                                   12.00
                            200
                                                                                                                                                                                   10.00
                            150                                7.85
                                                                                                                                                                                   8.00

                            100                                                                                                                                                    6.00
                                                                                                                                                                                   4.00
                            50                                                           1.82                                               1.65
                                                                                                                  1.21                                                             2.00
                                                                                                                                                              0.54         0.11
                             0                                                                                                                                                     0.00
Measles cases, MCV1 and MCV2 coverage by year—
WHO European Region, 2010–2022

                           120000                                                                                                                                                            100
                                                              95           95                                                     95           95            96
                                     94           94                                     94            94           93                                                 94       94
                                                                                                                                  91           91            92        91       91
                                                                           89            89            89           88
                           100000

                                                                                                                                                             104442
                                                  83          83
                                     80                                                                                                                                                      80
         Number of cases

                                                                                                                                                88693
                           80000

                                                                                                                                                                                                   % Coverage
                                                                                                                                                                                             60

                           60000
                                                                                                                                                                                             40
                           40000
                                                  33254

                                                                            32857

                                                                                                                                                                       12204
                                     30604

                                                                                                       28413
                                                                                                                                                                                             20
                                                              26788

                           20000

                                                                                                                    5273

                                                                                                                                  25872
                                                                                         18869

                                                                                                                                                                                159

                                                                                                                                                                                       937
                               0                                                                                                                                                             0
                                    2010     2011          2012          2013         2014          2015          2016         2017          2018           2019      2020     2021   2022

                                                                                                                    Year
                                                               Measles cases                            MCV1 coverage                                   MCV2 coverage
MCV1: first dose of measles-containing vaccine
MCV2: second dose of measles-containing vaccine

Data source: 1) Measles cases – monthly aggregated and case-based data reported by Member States to WHO/Europe or via ECDC/TESSy as of 02 March 2023.
             2) MCV1 and MCV2 coverage - WHO/UNICEF Estimates of National Immunization Coverage (WUENIC) as of 15 July 2022.                                                                                    14
Rubella
Updates including 2023

                         15
Five countries with the highest numbers of rubella cases—
WHO European Region, February 2022–January 2023

                        Poland                                                                                                                                      144

                        Türkiye                                                          44

                             Italy                    9
                                                                                                         Out of 221 rubella cases reported for February 2022 to January
                                                                                                         2023, 210 (95%) cases were reported by these 5 countries.
                    Germany                       7

                       Ukraine                   6

                                       0                       20                40                      60                     80                100   120   140         160

                                                                                                                   Number of cases

10 (20%) countries reported rubella cases in the rolling 12-months.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                 16
Rubella cases by month—WHO European Region,
2021–January 2023

                            35

                            30

                            25
          Number of cases

                            20

                            15

                            10

                             5

                             0

                                                                                                                     Nov

                                                                                                                           Dec

                                                                                                                                                                                                        Dec
                                                                                                               Oct

                                                                                                                                                                                            Oct

                                                                                                                                                                                                  Nov
                                           Feb

                                                                                                                                          Feb
                                                                      May

                                                                               Jun

                                                                                                                                  Jan

                                                                                                                                                                    Jun

                                                                                                                                                                                                               Jan
                                   Jan

                                                                                                                                                              May
                                                    Mar

                                                             Apr

                                                                                                                                                  Mar

                                                                                                                                                        Apr
                                                                                        Jul

                                                                                                                                                                          Jul

                                                                                                                                                                                Aug
                                                                                                 Aug

                                                                                                         Sep

                                                                                                                                                                                      Sep
                                                                                2021                                                                                  2022                                    2023
                                                                              (n=100)                                                                               (n=226)                                   (n=8)
                                                                                                                                                                                                              (n=8)
                                                                                                                                  Month
                                                                                              Lab confirmed                      Epi linked                   Clinically compatible

Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                17
Rubella
Latest update for 2022

                         18
Five countries with the highest numbers of rubella cases—
WHO European Region, 2022

                        Poland                                                                                                                                      152

                        Türkiye                                                      40

                    Germany                           9
                                                                                                         Out of 226 rubella cases reported for 2022, 217 (96%) cases
                                                                                                         were reported by these 5 countries.
                       Ukraine                        9

                             Italy                7

                                       0                  20                     40                      60                     80                100   120   140      160

                                                                                                                   Number of cases

10 (20%) countries reported rubella cases for 2022.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                              19
Rubella cases by month—WHO European Region,
2020–2022

                            60

                            50
          Number of cases

                            40

                            30

                            20

                            10

                             0                                                          Oct

                                                                                                                                                                 Oct

                                                                                                                                                                                                                                          Oct
                                                                                                    Dec
                                                                                              Nov

                                                                                                                                                                       Nov
                                                                                                                                                                             Dec

                                                                                                                                                                                                                                                Nov
                                                                                                                                                                                                                                                      Dec
                                                                                                                                                                                         Feb
                                       Feb

                                                                                                                Feb
                                             Mar

                                                                                                                                                                                               Mar
                                                                Jun
                                                                      Jul

                                                                                                          Jan

                                                                                                                      Mar

                                                                                                                                         Jun
                                                                                                                                               Jul

                                                                                                                                                                                   Jan
                                 Jan

                                                   Apr
                                                         May

                                                                            Aug
                                                                                  Sep

                                                                                                                            Apr

                                                                                                                                                     Aug
                                                                                                                                  May

                                                                                                                                                           Sep

                                                                                                                                                                                                                        Jul
                                                                                                                                                                                                     Apr

                                                                                                                                                                                                                              Aug
                                                                                                                                                                                                                                    Sep
                                                                                                                                                                                                           May
                                                                                                                                                                                                                  Jun
                                                                 2020                                                                     2021                                                                     2022
                                                               (n=190)                                                                  (n=100)                                                                  (n=226)
                                                                                                                                               Month
                                                                                              Lab confirmed                               Epi linked                          Clinically compatible

Criteria for date of case inclusion may differ in accordance with Member States’ surveillance systems.

Data source: Monthly aggregated and case-based data reported by Member States to WHO/Europe directly or via ECDC/TESSy data as of 02 March 2023                                                                                                       20
Links to measles and rubella information

•   WHO EpiData
    https://www.who.int/europe/teams/vaccine-preventable-diseases-immunization/who-epidata

•   Country slides for measles and rubella
    https://www.who.int/teams/immunization-vaccines-and-biologicals/immunization-analysis-and-insights/surveillance/monitoring/provisional-
    monthly-measles-and-rubella-data

•   WHO EpiBrief
    https://www.who.int/europe/teams/vaccine-preventable-diseases-immunization/who-epibrief

                                                                                                                                              21
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