Lung Cancer Conference 2020: A Time of Hope in Lung Cancer 19 - 21 February, 2020 Melbourne Convention and Exhibition Centre
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
8 Australian th Lung Cancer Conference 2020: A Time of Hope in Lung Cancer 19 - 21 February, 2020 Melbourne Convention and Exhibition Centre In collaboration with: Endorsed by: Proudly sponsored by: Platinum Gold Silver
Welcome from Lung Foundation Australia Welcome delegates of the 8th Biennial Australian mental health issues faced by Australians living with Lung Cancer Conference (ALCC). lung cancer. In 2020, the ALCC features multiple plenary sessions and offers delegates the opportunity In 2020, Lung Foundation Australia celebrates 30 to shape a unique learning experience through diverse years of service and support to Australians living concurrent sessions, ALTG member meetings, sponsor with and impacted by lung disease and lung cancer. symposiums, and an exciting combination of evolutions We acknowledge all those that have contributed to in lung cancer treatment, technology, research and making the last 30 years a tremendous success, and models of care. In another first, the program has been most importantly we look forward with optimism to a endorsed by the International Association for the brighter future, particularly for families whose lives have Study of Lung Cancer (IASLC). been forever changed by a lung cancer diagnosis. On behalf of Lung Foundation Australia, I would like to As Chairperson of Lung Foundation Australia, I warmly acknowledge and thank our event partners for their welcome you to Melbourne, Australia and thank you for generous sponsorship; without such support ALCC participating in the ALCC 2020. For the first time, the could not take place. Thank you also to the Conference conference has joined with the Australasian Lung Cancer Convenors Prof Kwun Fong and A/Prof Thomas John, the Trials Group Annual Scientific Meeting (ALTG-ASM) Conference Organising Committee and Lung Foundation and will deliver a comprehensive three-day program Australia staff for their efforts in shaping what will be to uniquely engage and unite lung cancer health an excellent event. professionals, consumer advocates and researchers from across Australia. We hope you enjoy the ALCC 2020 and take the time to share with us your expertise and experience so we The ALCC program represents the shared strategic may continue to improve the lives of patients and objectives of Lung Foundation Australia, the Australia families impacted by lung cancer and generate the & New Zealand Lung Cancer Nurses Forum (ANZ-LCNF) translational evidence required for improvements in and the ALTG. Together with ALTG, Lung Foundation everyday clinical practice. Australia seeks to design and conduct clinical trials which contribute meaningfully to the evidence base for high quality lung cancer diagnosis, treatment and long- Yours sincerely, term monitoring. As outlined in our lung cancer report, ‘Making Lung Cancer A Fair Fight: A Blueprint for Reform’, our current key advocacy priorities include: • Improving the quality of care for patients by increasing the number of lung cancer nurses. Prof Christine Jenkins AM Chairperson • Implementing a targeted national lung cancer Lung Foundation Australia screening program. • Increasing research funding for lung cancer commensurate to the burden of disease. These initiatives have inspired the conference theme 2020: A Time of Hope in Lung Cancer. The scientific program seeks to highlight the social, economic and 2 Australian Lung Cancer Conference 2020 Handbook
Contents Welcome from Lung Foundation Australia 2 Code of Conduct 4 Welcome from the Conference Co-Convenors 5 Meet the ALCC 2020 Local Organising Committee 6 International and Sponsored Speakers 7 Delegate and Speaker Information 11 Program Wednesday 19 February 13 Thursday 20 February 14 Friday 21 February 16 Welcome from the Australia and New Zealand Lung Cancer Nurses Forum (ANZ-LCNF) Chair 18 ANZ-LCNF Workshop Program 19 Faculty of Radiation Oncology Lung Interest Cooperative (FROLIC) Workshop Program 22 Abstracts: Poster Listing 24 Abstracts: Oral Presentations 26 How you can support us? 27 3 Australian Lung Cancer Conference 2020 Handbook
Acknowledgement of Country Lung Foundation Australia respectfully acknowledges the Boon Wurrung and Woiwurrung (Wurundjeri) peoples of the Kulin Nation as the Traditional Owners of the land upon which the Australian Lung Cancer Conference 2020 is being held. The Melbourne Convention and Exhibition Centre is built on their ancestral lands and we pay our respects to them, and to their elders, past, present and emerging. Code of Conduct The Local Organising Committee of ALCC 2020 welcomes all delegates to the conference, including consumer advocates. Whilst we are all united in the vision to improve outcomes for those affected by lung cancer, it is important to note that we come from varied backgrounds with unique experiences. To ensure that all delegates can make the most of the learning opportunities provided, in a safe and respectful environment, we ask you to please read and observe the following throughout your conference experience. • We support and encourage consumer advocates to participate in the conference program and their right to be heard and respected. Consumer advocates are permitted to ask questions in allocated question times and enter the exhibition area when wearing their conference lanyard. • A dedicated Consumer Advocates Lounge will be open (Room 101) throughout the course of the conference. This area will be a quite space where refreshments will be available for consumer delegates and approved users only. • The program is designed to increase understanding of the advances in lung cancer research, treatment and care. When considering your questions to speakers, please note some of the tests and/or treatments presented may not yet be available in Australia. • Health professionals, researchers and pharmaceutical representatives are unable to provide consumer advocates with individualised advice on medical conditions or any aspect of treatment. • We are committed to providing a conference environment in accordance with the Medicines Australia Code of Conduct and specifically ask that all delegates and exhibitors are aware that individual promotion of products to the general public is in breach of the Code. 4 Australian Lung Cancer Conference 2020 Handbook
Welcome from the Conference Co-Convenors On behalf of Lung Foundation Australia, it gives us Forum (ANZ-LCNF) Nursing and Allied Health enormous pleasure to welcome you to Melbourne Workshop and the Faculty of Radiation Oncology and to thank you for participating in the 8th Lung Interest Cooperative (FROLIC) workshop. We Biennual Australian Lung Cancer Conference (ALCC). are delighted to welcome delegates from across Australia, New Zealand and the international For the first time the ALCC and the Australasian representatives, who collectively provide valuable Lung Cancer Trials Group Annual Scientific insight into local and international advances in Meeting (ALTG-ASM) have joined forces to deliver lung cancer. We thank you for attending and for a comprehensive program which will no doubt the significant support provided by sponsors uniquely engage and unite lung cancer health and exhibitors. Please take the time to visit our professionals, consumers and researchers. We are exhibitors during the designated breaks. We hope delighted that the event has been endorsed by the you enjoy the meeting and share with us your International Association for the Study of Lung expertise and experience so we can continue to Cancer (IASLC). improve outcomes for lung cancer and generate The ALCC 2020 conference program represents the evidence required for improvements in clinical the strategic objectives of both Lung Foundation practice. Australia and ALTG. Lung Foundation Australia’s current key advocacy efforts include improving Yours sincerely, access to treatment and lung cancer nurses, implementing a national lung cancer screening program and funding of lung cancer research commensurate with the burden of disease. These initiatives, as outlined in ‘Making Lung Cancer A Fair Fight: A Blueprint for Reform’, inspire the theme of ALCC 2020. The report addresses the social, economic and mental health issues of Australians living with lung cancer. Together, with initiatives by ALTG to design and conduct trials which contribute to evidence for high quality diagnosis, treatment and monitoring of lung cancer, we strive to effect change in the health and wellbeing outcomes of Professor Kwun Fong Associate Professor lung cancer patients. Co-Chair, Local Thomas John The ALCC 2020 program is an exciting combination Organising Committee Co-Chair, Local of evolutions in treatment, technology, research Organising Committee and supportive care. The conference will feature oral and poster sessions, sponsored symposiums and ALTG member meetings. The pre-conference events include Australia New Zealand Lung Cancer 5 Australian Lung Cancer Conference 2020 Handbook
Meet the Local Organising Committee Professor Kwun Fong Dr Ashanya Malalasekera Thoracic and Sleep Physician at The Prince Charles Medical Oncologist and Senior Lecturer at the Hospital and Professor with the University of University of Sydney. Queensland School of Medicine. Associate Professor Rob Stirling Associate Professor Thomas John Respiratory Specialist at The Alfred Hospital, Medical Oncologist at the Peter MacCallum Melbourne and Chairman of the Lung Cancer Hospital in Melbourne. Multidisciplinary Team. Professor Fraser Brims Dr Jaclyn Yoong Consultant Respiratory Physician and Head of Palliative Care Physician and Medical Oncologist at Department Sir Charles Gairdner Hospital. Northern Health and Monash Health. Dr Vanessa Brunelli Dr Lisa Briggs Research Fellow at Queensland University of - Consumer Advocate and 5-year Stage IV lung Technology and Nurse Researcher at Princess cancer survivor Alexandra Hospital. - Passionate about improving the visibility of lung cancer in Australia Mary Duffy, RGN/RSCN, RSM Graduate Diploma of Advanced Nursing in - Wife and Mum Oncology and Palliative care. Master of Philosophy - Victorian Finalist - 2020 Australian of the Year by Nursing Research. ‘Local Hero’ category - Member, Lung Cancer Patient Advisory Dr Lara Edbrooke Committee, Lung Foundation Australia Grade 4 Allied Health Researcher and Physiotherapist at Peter MacCallum Hospital. Tom Wood - Consumer Advocate Dr Kerry Hancock - Passionate about equity, technology and news General Practitioner and Principal, Chandlers Hill Surgery, Happy Valley SA. - Son, Brother and Carer - Member, Lung Cancer Patient Advisory Associate Professor Gerry Hanna Committee, Lung Foundation Australia Director of Radiation Oncology at the Peter MacCallum Cancer Centre, Melbourne. Associate Professor Marie-Liesse Asselin-Labat Joint-Head of the Personalised Oncology Division at the Walter and Eliza Hall Institute of Medical Research in Melbourne. 6 Australian Lung Cancer Conference 2020 Handbook
International and Sponsored Speakers Professor Michael Boyer AM Professor Michael Boyer is a Medical Oncologist and the Chief Clinical Officer at Chris O’Brien Lifehouse. He is a Conjoint Professor of Medical Oncology (Thoracic Oncology) at the University of Sydney and Director of the Sydney Catalyst Translational Cancer Research Centre. Professor Boyer has over 25 years of experience in the management of thoracic malignancies and head and neck cancers. His main research interest is in clinical trials of new agents in the management of lung cancer, mesothelioma and head and neck cancers. He is the author of over 170 publications, has given numerous national and international presentations, both invited and selected from abstract submission, and is actively involved in the lung cancer community. Dr Federico Cappuzzo MD Dr Federico Cappuzzo has been the Director of Medical Oncology at AUSL della Romagna-Ravenna since April 2016 and in January 2017 he became the Director on Hematology and Oncology Department. Dr Cappuzzo is a member of the Italian Association in Medical Oncology, European Society for Medical Oncology, American Society Clinical Oncology and International Association for the Study of Lung Cancer (IASLC) and since 2006 as a Member of the editorial board of Lung Cancer. In January of 2016, he became the Chairman of the Educational Committee of IASLC. In 2006, 2009 and 2012 he received research grants from the Italian Association for Cancer Research on targeted therapies in lung cancer and is the author of more than 200 papers in peer-review journals, mainly in translational research in lung cancer. Dr Marina Chiara Garassino Dr Marina Chiara Garassino is the Chief of the Thoracic Oncology Unit at the prestigious Istituto Nazionale dei Tumori cancer institute in Milan, Italy. She leads the strategy for clinical and translational research in advanced and locally advanced non-small cell lung cancer, small-cell lung cancer, mesothelioma and thymic malignancies. Dr Garassino's main research interests include; the development of new drugs, therapeutic strategies and biomarkers. Dr Garassino has contributed to over 120 peer-reviewed publications, including credits as first or last author in the New England Journal of Medicine, Lancet Oncology, Journal of Clinical Oncology and Annals of Oncology. Dr Garassino has delivered many presentations at international conferences including American Association of Cancer Research (AACR), American Society of Clinical Oncology (ASCO), European CanCer Organisation, European Society of Medical Oncology (ESMO), World Conference on Lung Cancer (WCLC). Dr Garassino is currently serving as ESMO Council Chair of the National Societies Committee and serves on several ESMO Committees (Public Policy extended Committee, Press Committee, Women for Oncology Committee, Lung Cancer faculty, Membership Committee). Dr Garassino is working on both ESMO, WCLC and ASCO annual congress Lung Cancer Track (2019). Dr Garassino is the founder and president of Women for Oncology Italy. 7 Australian Lung Cancer Conference 2020 Handbook
Professor Nir Peled MD PhD Professor Nir Peled is Head of the Oncology Division at the Legacy Heritage Oncology Center and Dr Larry Norton Institute at Soroka Medical Center, Ben- Gurion University, Beer Sheva, Israel. He is board certified in internal medicine, pulmonology, and medical oncology. An expert in thoracic oncology, Professor Peled is a Board Member at the International Association for the Study of Lung Cancer (IASLC) and the past Chair of the Thoracic Cancer Assembly of the European Thoracic Society and the past Chair of the Screening Committee of the International Association of Lung Cancer. Professor Peled’s research focuses on the wide translational and clinical perspectives of lung cancer, including personalised targeted therapy, immunotherapy, cancer evolution, biomarker development, and early detection of this disease. He has published nearly 200 peer-reviewed articles, including guidelines on the early diagnosis of lung cancer, biomarker development, and treatment of advanced disease. Professor Peled is on the editorial board of numerous journals, including the Journal of Thoracic Oncology and other lung-cancer related publications. In October 2019 he became a board member of the IASLC and member of its financial committee. Professor Angela Mary Tod Professor of Older People and Care, Division of Nursing and Midwifery at the University of Sheffield. For the last 20 years Professor Tod has worked in research with a particular focus in lung cancer and mesothelioma patient experience studies. Professor Todd established and chaired the Lung Cancer Nursing UK Research Interest Group with a portfolio of research projects in collaboration with Mesothelioma UK. Professor Tod is also a Joint Principle Investigator on a National Strategic Research Alliance between the University of Sheffield and the Royal College of Nursing in the UK. This alliance incorporates a programme of work on new and emerging nursing roles including advanced and specialist nursing. A/Prof Nick Pavlakis A/Prof Nick Pavlakis is a senior staff specialist in the Department of Medical Oncology at Royal North Shore Hospital and conjoint Associate Professor in the Faculty of Medicine University of Sydney. He is currently Clinical Services and Trials Director of the Northern Cancer Institute at St Leonards, President of the Australasian Lung Cancer Trials Group (ALTG) and President of the Clinical Oncologic Society of Australia (COSA). His background includes a PhD in anti-angiogenic cancer drug development and a Masters of Clinical Epidemiology, University of Sydney. He has extensive experience in clinical research as clinical lead or site Primary Investigator in national and international clinical trials in lung cancer, mesothelioma and gastrointestinal cancers, as well as translating evidence into practice with lung cancer systematic reviews and guideline development. 8 Australian Lung Cancer Conference 2020 Handbook
A/Prof Trishe Leong A/Prof Trishe Leong is the Medical Director of Pathology and Director of Anatomical Pathology at Austin Health, Melbourne, where she has been involved in the supervision and reporting of diagnostic molecular testing for solid tumours since 2015. She received her undergraduate medical degree from the University of Adelaide and trained in Anatomical Pathology in Melbourne, being admitted to Fellowship in 2006. Following this she worked at Monash Medical Centre and the Victorian Cytology Service, where she was Deputy Managing Pathologist, before joining Austin Health in 2010. She previously served from 2015- 2018 as the Honorary Treasurer of the Australasian Division of the International Academy of Pathologists, followed by a term as Divisional Vice President, and is the current Secretary/Treasurer of the Royal College of Pathologists Australasia. 9 Australian Lung Cancer Conference 2020 Handbook
Please take time to Thank you to our generous event sponsors visit the exhibition Platinum and engage with our event sponsors. Download the myINTERACT app to collect points and win prizes! Trade Displays Gold • Becton Dickinson • Roche Foundation Medicine • Takeda • Maurice Blackburn Lawyers Silver • Healthinc • Cancer Council Victoria • Victorian Tumour Summits See you at the ALCC 2020 Dinner! Thursday 20 February 2020 Join us for dinner and live entertainment as we announce and celebrate the recipients of the Lung Foundation Australia Lung Cancer Research Awards for 2020. Welcome drinks from 7:00pm for 7:30pm commencement. Places are limited and registration is required to attend. Visit events.ozaccom.com.au to register. 10 Australian Lung Cancer Conference 2020 Handbook
Delegate and Speaker Information Registration desk hours MCEC Free Wifi Registration desk is located on Level 1, open from: Free WIFI is available at the conference. To connect to WIFI, select the MCEC Free Wednesday 19 February: 7:30am – 4:30pm WIFI Network, no password is required. Thursday 20 February: 6:30am – 4:30pm Friday 21 February: 6:30am – 2:00pm Conference Catering All conference catering will be served in the exhibition Speaker Preparation Room area. Delegates who have advised special dietary requirements will have access to a separate buffet The speaker preparation room is located on Level 1, which will be supervised by an events staff member Room 107 and is open: for your convenience. If you are attending a catered sponsor symposium, please arrive early to collect Thursday 20 February: 6:30am – 5:00pm your meal. Friday 21 February: 6:30am – 4:00pm Evaluation Social Media Your opinion is important to us! A post-event survey The official conference social media channels are: will be available from morning tea on Friday 21 February via the conference app. Please take the time Twitter: @Lungfoundation to complete the evaluation to help us improve future Facebook: @Lungfoundation ALCC events. After completing the evaluation, you Instagram: @Lungfoundation will have access to the speaker presentations. LinkedIn: Lung Foundation Australia Consumer Advocates Lounge Hashtag #ALCC2020 and tag us social media. The dedicated consumer advocates lounge is located in Room 101 and is accessible throughout the Event Coordinator conference by consumer advocate delegates only. Lisa Cunningham, Senior Event Manager, Medical Meetings Conference App Contact number: 0435 569 096 Download the myINTERACT app to: Email: lisa@medicalmeetings.com.au - View the ALCC program, abstracts and exhibitor Should you require assistance or have questions details throughout the event please speak with a member - Complete session evaluations of the Medical Meetings team. - Engage with exhibitors and win great prizes - Snap and upload the best conference photo to win movie passes. Poster Display myINTERACT Posters will be on display throughout the duration is available on of ALCC 2020 in Room 104 and oral presentations iPhone, Android, will take place during morning tea and lunch breaks. Please take time to view the posters over a Tablet and Desktop. complimentary coffee, kindly provided by MSD. 11 Australian Lung Cancer Conference 2020 Handbook
Together. Today and Tomorrow Lung cancer patients in mind People, products and services working together to support you and your patients with lung cancer atezolizumab atezolizumab bevacizumab bevacizumab alectinib 150 alectinib 150 mg mg capsules capsules erlotinib erlotinib Please review the Product Information for TECENTRIQ (www.roche-australia.com/productinfo/tecentriq), AVASTIN (www.roche-australia.com/productinfo/avastin), ALECENSA (www.roche-australia.com/ productinfo/alecensa) and TARCEVA (www.roche-australia.com/productinfo/tarceva) before prescribing, available on request from Roche Products Pty Limited. Roche Roche Products Products Pty Pty Limited, Limited, ABN ABN 70 70 000 000 132 132 865, 865, Level Level 8, 8, 30–34 30–34 Hickson Hickson Road, Road, Sydney Sydney NSW NSW 2000. 2000. Medical Medical Information: Information: 1800 1800 233 233 950. 950. ®Registered ® Registered Trademark Trademark EMVTEC462 EMVTEC462 EC-AU-9128 EC-AU-9128 PreparedJan20 PreparedJan20
Wednesday 19 February Time Session Speaker Room 8:00am - 5:00pm Australia and New Zealand Lung For full workshop details please see Cancer Nurses Forum (ANZ-LCNF) page 19 Nursing and Allied Health Workshop 9:00am - 4:00pm Faculty of Radiation Oncology For full workshop details please see Lung Interest Cooperative (FROLIC) page 22 Workshop 9:30am - 5:00pm Australasian Lung Cancer Trials Room 101/102 Group (ALTG) Clinical Development Workshop and Open SAC Meeting 10:00am - 4:00pm Lung Cancer Community Forum Room 103 NOW PBS LISTED First-line treatment of Stage IV mNSCLC, no EGFR/ALK/ROS1 genomic tumour aberrations; WHO PS 0-1; further eligibility criteria apply1 In PD-L1 Expressors and Non-Expressors 2 HELPING TO REDEFINE SURVIVAL EXPECTATIONS FOR PATIENTS WITH mNSCLC*†2 *Non-Squamous: without EGFR/ALK genomic tumour aberrations, KEYTRUDA + pemetrexed + platinum chemotherapy vs pemetrexed and platinum chemotherapy (HR=0.49; 95% CI, 0.38-0.64; P
Thursday 20 February Time Session Speaker Room 7:00am - 8:00am Australasian Lung Cancer Trials Room 102 Group MAC Meeting (ALTG members only) 8:00am - 9:00am Opening ceremony Prof Kwun Fong Room 105/106 Prof Tom John 9:00am - 10:00am Keynote presentations: Dr Marina Garassino Room 105/106 Prof Bin Jalaludin Future directions for research in Lung Cancer Air quality and lung health 10:00am - 10:30am Morning tea (exhibition area) Poster presentations (Room 104) 10:00am - 12:30pm Palliative care symposium Dr Jaclyn Yoong Room 103 Dr Michael Chapman Dr Eswaran Waran Prof David Currow Prof Jane Phillips 10:00am - 12:30pm Plenary: Quality in Diagnostics and A/Prof Marie-Liesse Labat Room 105/106 Care: Dr Stephen Fox ‘Leaps & bounds’ in lung cancer in Dr Federico Cappuzzo 2020 A/Prof Gerry Hanna A/Prof Gavin Wright Dr Lara Edbrooke Ms Mary Duffy 11:30am - 12:30pm Pfizer Symposium: Lung pathology in A/Prof Nick Pavlakis Room 109 the era of targeted therapies: ROS1 A/Prof Trishe Leong testing in patients with advanced non-small cell lung cancer 12:30pm - 1:30pm Lunch (exhibition area) Poster presentations (Room 104) 12:30pm - 2:00pm Roche Symposium: Non-squamous Dr Federico Cuppuzzo Room 110 NSCLC: Selecting the right treatment regimen for each patient 1:30pm - 3:00pm Symposium: Basic Science Dr Melvin Chin Room 102 Novel insights into the biology of Dr Clare Weeden thoracic cancers Dr Jason Cain Dr Mark Adams Dr Sarah Best Dr Marian Burr 14 Australian Lung Cancer Conference 2020 Handbook
Thursday program continued Time Session Speaker Room 1:30pm - 3:30pm Plenary: Hope & Equity Prof Ben Solomon Room 105/106 Reinventing clinical trials A/Prof Nick Pavlakis A/Prof Rob Stirling A/Prof Gavin Wright A/Prof Tom John Renae Grundy Lisa Briggs Tom Wood Melanie Lane Lillian Leigh 1:30pm - 3:30pm Living with Thoracic Cancer and Prof Linda Denehy Room 109 Beyond: Dr Vin Calvaheri Exercise in lung cancer Ms Jane Turner Prof Rob Newton Dr Jin-Soo Kim Ms Nasreen Kadaan 1:30pm - 3:30pm Oral abstract presentations: Room 103 Screening and early detection 3:30pm - 4:00pm Afternoon Tea 4:00pm - 5:00pm Oral abstract presentations: Room 103 Epidemiology 4:00pm - 5:30pm Plenary: Living with Thoracic Cancer Ms Olivia Wong Room 105/106 and Beyond: Dr Catherine Holiday Holistic long-term care A/Prof Joel Rhee Dr Maria Ftanou Dr Jaclyn Yoong Ms Jacqueline Lesage Dr Melissa Yang 4:00pm - 6:00pm ALTG clinical trial concepts Room 102 6:00pm - 7:30pm MSD Symposium: Redefining Prof Nir Peled Room 103 survival expectations for lung cancer patients 7:00pm - 11:00pm ALCC 2020 Conference dinner & Lung Foundation Australia lung Room 109/110 cancer awards 15 Australian Lung Cancer Conference 2020 Handbook
Friday 21 February Time Session Speaker Room 7:00am - 9:00am ALTG Strategic planning meeting Room 102 (ALTG members only) 7:30am - 9:00am BMS: What is the future of Prof Michael Boyer Room 101 immunotherapy in NSCLC? 9:00am - 10:00am Keynote presentation: Prof Angela Tod Room 105/106 Prof Martin Phillips Working Together: The power of a multi-disciplinary approach in lung cancer treatment & care E-cigarettes: Good intentions gone awry? The harmful consequences 10:00am - 10:30am Morning tea (exhibition area) Poster presentations (Room 104) 10:30am - 12:30pm Oral abstract presentations: Room 102 Medical oncology 10:30am - 12:30pm Oral abstract presentations: Are we Room 103 delivering best practice treatment? 10:30am - 12:30pm Plenary: Quality in Diagnostics and Dr Vivienne Milch Room 105/106 Care: (Cancer Australia) Lung cancer screening in Australia Dr Henry Marshall A/Prof Paul Mitchell Dr Brendan Adler Dr Niranjan Karanth Prof Nir Peled 10:30am - 12:30pm Symposium: Borderline inoperable Mr Julian Gooi Room 109 disease Dr Susan Harden A/Prof Siven Seevanayagam Dr Fiona Hegi-Johnson 12:30pm - 1:30pm Lunch (exhibition area) Poster presentations (Room 104) 16 Australian Lung Cancer Conference 2020 Handbook
Friday program continued Time Session Speaker Room 12:30pm - 2:00pm AstraZeneca Symposium: Putting Dr Marina Garassino Room 110 evidence into practice in locally advanced and metastatic NSCLC 1:30pm - 3:00pm Oral abstract presentations: Room 102 Basic science 1:30pm - 3:30pm Oral abstract presentations: Room 103 Data-driven quality 1:30pm - 3:30pm Hope & Equity: Toward 2030 in lung Ms Lisa Briggs Room 105/106 cancer Mr Tom Wood Prof David Ball Prof Danielle Mazza A/Prof Rob Stirling A/Prof Angela Tod 1:30pm - 3:30pm Symposium: Mesothelioma Ms Dimitra Dubrow Room 109 (proudly sponsored by Maurice Prof Fraser Brims Blackburn Lawyers) Dr Nicola Waddell Prof Ken O'Byrne A/Prof Gavin Wright Prof Anna Nowak A/Prof Gerry Hanna 3:30pm - 4:30pm Abstract Awards followed by Prof Kwun Fong Room 105/106 Closing Ceremony A/Prof Tom John 4:30pm - 4:45pm Afternoon tea Thank you for joining us at ALCC 2020! 17 Australian Lung Cancer Conference 2020 Handbook
Welcome from the ANZ-LCNF Chair As Chair of the Australia and New Zealand Lung Cancer Nurses Forum (ANZ-LCNF) I am very pleased to extend my warmest welcome to everyone attending the Australian Lung Cancer Conference 2020 in Melbourne. The care provided by Lung Cancer Nurse Specialists improves clinical outcomes for patients with lung cancer. As 2020 is the International Year of the Nurse, I am particularly excited we are hosting the ANZ-LCNF workshop for nurses and allied health. This provides us with a great opportunity for networking and collaborating with clinicians, research experts, and many health professional members. It also gives us a unique occasion to shape how we can contribute to Lung Foundation Australia’s current key advocacy efforts as outlined in the strategic document ‘Making Lung Cancer A Fair Fight: A Blueprint for Reform’. It is my great pleasure to welcome Professor Angela Mary Tod as the international nurse keynote speaker at this years’ workshop and conference. I encourage all nurse an allied health attendees to enjoy all sessions provided in the ALCC 2020 program. Finally, I would like to echo the words of thanks extended by our conference convenors, Prof Kwun Fong and A/Prof Tom John to the sponsors and exhibitors. Mary Duffy, APN, Lung Cancer Nurse Coordinator 18 Australian Lung Cancer Conference 2020 Handbook
ANZ-LCNF: This event is proudly sponsored by Nursing and Allied Health Workshop Program Wednesday 19 February Session 1: Diagnostics and Quality of Care Chair: Ms Mary Duffy, APN Time Session Speaker 7:45am for 8:00am Registration start 8:00am - 8:10am Welcome Ms Mary Duffy APN, ANZ-LCNF Chair 8:10am - 8:50am The impact of the specialist lung cancer Prof Angela Tod nurse model on the health & wellbeing outcomes of patients and families 8:50am - 9:20am Lung cancer optimal care pathways Prof Robert Thomas 9:20am - 9:50am 2020: A year in review of lung cancer Dr Surein Arulananda 9:50am - 10:30am Roche sponsored session: Holistic care Ms Helen Westman of the patient on Tecentriq and Avastin Mr Michael Cooney combination therapy 10:30am - 10:50am Morning tea Session 2: Hope & Equity Chair: Dr Vanessa Brunelli 10:50am - 11:15am The lived experience of lung cancer Mr Kane Morris 11:15am - 11:35am Telehealth to improve access and equity to Dr Vanessa Brunelli cancer survivorship care 11:35am - 11:55am Equitable access to treatment in minority Mrs Carolyn Riordan populations 11:55am - 12:15am Radiotherapeutic advances in the context of Dr Nikki Plumridge cerebral metastases 12:15pm - 12:35pm Respiratory health and air quality Dr Alistair Miller 12:35pm - 1:05pm Lunch 19 Australian Lung Cancer Conference 2020 Handbook
ANZ-LCNF: program continued Session 3: Living with Thoracic Cancer and Beyond Chair: Dr Lara Edbrooke Time Session Speaker 1:10pm - 1:30pm Symptom management – challenges faced Ms Helen Westman with new immune-oncology therapies 1:30pm - 1:50pm Cancer-related fatigue management Dr Elizabeth Pearson 1:50pm - 2:10pm Sarcopenia and cancer-related malnutrition Dr Nicole Kiss 2:10pm - 2:30pm Swallowing and voice outcomes after Dr Jacqui Frowen radiotherapy for SCLC 2:30pm - 2:45pm Exercise across the lung cancer continuum Dr Lara Edbrooke 2:45pm - 3:05pm Afternoon tea Session 4. Improving Nurse and Patient Outcomes in Lung Cancer Chair: Dr Vanessa Brunelli Time Session Speaker 3:10pm - 3:30pm Smoking cessation in Australia: Practical Ms Kelly Burton strategies 3:30pm - 3:50pm Clinical debrief and good self mental health Ms Tessa Moriarty 3:50pm - 4:10pm ANZ-LCNF research and education update Dr Vanessa Brunelli Ms Renae Grundy – PhD research 4:10pm Close Ms Mary Duffy APN, ANZ-LCNF Chair 4:20pm - 5:00pm Drinks and networking 20 Australian Lung Cancer Conference 2020 Handbook
THE STANDARD OF CARE FOR STAGE III UNRESECTABLE NSCLC that has not progressed post platinum-based CRT1–5 UNPRECEDENTED 3-YEAR OVERALL SURVIVAL BENEFIT in patients with Stage III unresectable NSCLC whose disease has not progressed post platinum-based CRT (vs placebo; HR 0.69, 95% CI, 0.55-0.86).4-6 PLEASE CLICK HERE TO REVIEW FULL PRODUCT INFORMATION BEFORE PRESCRIBING. FURTHER INFORMATION AVAILABLE ON REQUEST FROM ASTRAZENECA. PBS Information: This product is not listed on the PBS. CI: confidence interval; CRT: chemoradiation therapy; HR: hazard ratio; NSCLC: non-small cell lung cancer. References: 1. NCCN Guidelines. Non-small cell lung cancer v4.2019 (April 29 2019). Available at: www.nccn.org. 2. EviQ. Non small cell lung cancer durvalumab. ID: 3512 v.1. Available at: https://www.eviq.org.au. 3. Antonia SJ, et al. N Engl J Med 2018; 379:2342-50. 4. IMFINZI Approved Product Information. 5. McCall NS, et al. Clin Cancer Res 2018;24:1271-6. 6. Gray JE, et al. ASCO 2019. Poster 8526. IMFINZI® is a trademark of the AstraZeneca group of companies. Registered user AstraZeneca Pty. Ltd. ABN 54 009 682 311. 66 Talavera Road, Macquarie Park, NSW 2113. www.astrazeneca.com.au. For Medical Information enquiries: 1800 805 342 or medinfo.australia@astrazeneca.com. To report an adverse event: 1800 805 342 or via https://aereporting.astrazeneca.com. AU-7238. WL303014. Date of preparation: January 2020. 21 Australian Lung Cancer Conference 2020 Handbook
Faculty of Radiation This event is proudly sponsored by Oncology Lung Interest Cooperative (FROLIC) Workshop Program Wednesday 19 February Co-Chairs: Dr Louis Lao and A/Prof Gerry Hanna Wednesday 19 February Time Presentation Speaker 9:00am - 9:15am Welcome A/Prof Gerry Hanna Dr Louis Lao 9:15am - 10:15am Lung Cancer Radiotherapy: Where have we come Prof David Ball from, where are we now and where are we going to? 10:15am - 10:45am Morning tea 10:45am - 11:30am Radiotherapy in small cell lung cancer Dr Eric Hau 11:30am - 12:00pm What is the optimal systemic therapy regimen to Dr Marina Garassino used in combination chemoradiation in NSCLC? 12:00pm - 12:30pm AstraZeneca Sponsored Session: Dr Marina Garassino Considerations for CRT administration in stage III Prof David Ball to limit post treatment complications? 12:30pm - 1:30pm Lunch 1:30pm - 1:45pm Motion management in NSCLC radiotherapy Dr Louise Nardone 1:45pm - 2:05pm Optimal dose and fractionation in the treatment Dr Louis Lao of NSCLC with radiotherapy? 2:05pm - 2:20pm Proton therapy – Where did we get to? Dr Fiona Hegi-Johnson 2:20pm - 2:40pm Radiotherapy in thymoma and mesothelioma A/Prof Gerry Hanna 2:40pm - 3:10pm Afternoon Tea 3:10pm - 3:55pm Management of oligometastatic disease in NSCLC: A/Prof Shankar Siva Who, what, where, why and when? 3:55pm - 4:00pm Session close A/Prof Gerry Hanna Dr Louis Lao 22 Australian Lung Cancer Conference 2020 Handbook
Australasian Lung Cancer Trials Group (ALTG) The Australasian Lung Cancer Trials Group (ALTG) is a member-based organisation representing respiratory physicians, medical oncologists, radiation oncologists, palliative care specialists, cardiothoracic surgeons, scientists, nurses, clinical trial professionals and consumer representatives. ALTG objectives are: Benefits of ALTG membership include: • To facilitate participation in the • A network of multidisciplinary professionals development, conduct, evaluation, across Australia and New Zealand who are reporting of clinical trials in lung cancer and passionate about research for lung and thoracic mesothelioma. cancers, such as clinicians, nursing, allied health, • To promote the use of clinical trials consumer and industry representatives. in evaluating new treatments and • Support for developing your research ideas management approaches for lung cancer for investigator-initiated studies from and mesothelioma. concept to protocol and study conduct. • To contribute to the translation of clinical • Regular member meetings to develop trial findings into clinical practice. research ideas and hear speakers on cutting- edge research topics. Join ALTG today • Educational opportunities including the ALTG Preceptorship in Lung Cancer and the ALTG Visit altg.com.au Annual Scientific Meeting. • Financial support to attend ALTG meetings in the form of travel grants.
Abstracts: Poster Listing Dr Ayman Alidina - Immunotherapy in mesothelioma: A/Prof Chee Lee - A phase 2 trial of Durvalumab (MEDI4736) Case studies from a regional cancer centre and Tremelimumab with chemotherapy in metastatic EGFR mutant non-squamous non-small cell lung cancer following Dr Prachi Bhave - Optimising pathways to maximal progression on EGFR Tyrosine Kinase Inhibitors (ILLUMINATE) pathological diagnosis of metastatic non-small cell lung cancer Dr Jennifer Lim - Predictive biomarkers for platinum sensitivity in advanced non-small cell lung cancer – Dr Charlotte Chen - Surgical treatment of non-small study schema cell lung cancer in octogenarians: A single centre retrospective study Prof Linda Mileshkin - A randomised phase 3 trial of early referral to palliative care for patients with Mrs Kirsten J Duggan - Lung cancer extent of disease, advanced thoracic malignancies (PEARL) treatment patterns and survival - The effect of culturally and linguistically diverse status in south Dr Cienne Morton - Survival outcomes and prognostic western Sydney factors in unresectable Stage III NSCLC treated with concurrent chemoradiotherapy. A single institution audit Dr James Farag - Surgical management of pulmonary from the Princess Alexandra Hospital, Brisbane artery angiomatoid fibrous histiosarcoma Dr Sara Pacella - Prognostic value of restaging 18F- FDG Ms Tracey Guan - Lung cancer in patients aged 65+ PET/CT in patients with small cell lung cancer years: Who do we treat and how do we treat them? Ms Brielle Parris - Molecular testing of small Dr Harshan Jeyakumar - Improving regional lung cancer bronchoscopy specimens using NanoString technology optimal care pathway compliance through a rapid-access respiratory clinic Miss Sobasha Perera - Surveillance, patterns of recurrence and survivorship in early stage non-small cell lung cancer patients For more information, visit us at Booth 10 © 2020 Bristol-Myers Squibb. OPDIVO® is a registered trademark of Bristol-Myers Squibb Company. BMS Medical Information: 1800 067 567. Bristol-Myers Squibb Australia Pty Ltd, ABN 33 004 333 322, 4 Nexus Court, Mulgrave, VIC 3170. 1506AU2000940-01. Date of preparation: February 2020. BRMSCH1514. 24 Australian Lung Cancer Conference 2020 Handbook
Abstracts: Poster Listing continued Miss Sophie Pickles - Investigating the role of Dr Simon Slader - The concordance between clinical mitochondria-targeted H2S donors for the treatment of and pathological TNM stage in non-small cell lung NSCLC cancer, a retrospective audit Dr Kuan Pin Lim - Differences in lung cancer stage Ms Catherine Smith - Demographics of patients with distribution in private and public hospital settings lung cancer diagnosed in the upper South Island of New Zealand: A ten-year audit Miss Aleksandra Rajapakse, Dr Connor O’Leary & Mr Ken O’Byrne - Autoimmune inner ear disease in an Dr Ashley Tan - Nobody expected the Spanish advanced lung cancer patient treated with nivolumab Inquisition! Lung cancers found in unexpected ways Dr Nicole Rankin - Implementation of lung cancer Dr Ashley Tan - Early stage lung cancers detected in multidisciplinary care: A rapid review of evidence- asymptomatic patients in an Australian private hospital practice gaps setting Ms Korinna Selga - Patient reported outcome Dr Harshil Trivedi - Multidisciplinary team patterns measures in a Western Australian pilot group of lung of care for Stage III NSCLC and evaluation of guideline cancer patients: Implementation of the continuous adherence – single-centre analysis improvement in care - Cancer (CIC Cancer) Project Dr Hannah Wade - Surgical rates in Stage I NSCLC: Audit Dr Clare Senko - Cancer-testis antigens (CTAs), PD- of multidisciplinary team practice L1 and overall survival in surgical non-small cell lung Dr Veronica Wong & Dr Ashley Heyworth - FDG cancer: Potential immune mechanisms PET/CT for the staging of mediastinal lymph node Dr Prajwol Shrestha - A rare case of bullous pemphigoid involvement in lung cancer associated with squamous cell carcinoma of lung showing remarkable response to carboplatin based chemotherapy in elderly: Case report and literature review In the era of molecular targeted therapies1 Unlock the potential of the only TKI approved for ROS1-positive NSCLC2-5 At diagnosis, request… EGFR ALK ROS 1 …testing Recommended by ASCO, ESMO and NCCN6-9 PBS information: Authority required for the treatment of ALK+ & ROS1+ advanced NSCLC. Refer to the PBS Schedule for full authority information. PLEASE REVIEW PRODUCT INFORMATION BEFORE PRESCRIBING. PRODUCT INFORMATION IS AVAILABLE FROM THE TRADE DISPLAY. References: 1. Nicholson AG et al. Sample Acquisition, Processing, and General Diagnostic Procedures. In Tsao MS, et al. IASLC Atlas Of ALK and ROS1 Testing in Lung Cancer. Second Edition. 2016. International Association for the Study of Lung Cancer, Aurora, CO, USA. 2. XALKORI Approved Product Information. 3. ALECENSA® (alectinib) Approved Product Information. 4. ZYKADIA® (ceritinib) Approved Product Information. 5. Shaw AT, et al. N Engl J Med. 2014; 371:1963-71. 6. National Comprehensive Cancer Network (NCCN). Non-small ® Registered trademark. Cell Lung Cancer. Version 3. 2019 January 18, 2019. Available at www.nccn.org. Accessed February 2019. 7. Kalemkerian GP, et al. J Clin Pfizer Australia Pty Limited, Sydney, Australia. Oncol. 2018; 36 (9): 911-919. 8. Planchard D, et al. on behalf of the ESMO Guidelines Committee. Ann Oncol. 2018; 29 (Supplement_4): Pfizer Medical Information: 1800 675 229. iv192-iv237. 9. Pavlakis, N et al . Pathology. 2019; 51(7):673-680 PFE1247. PP-XLK-AUS-0264. February 2020. 25 Australian Lung Cancer Conference 2020 Handbook PFE1247_Xalkori_186x153.5mm_Ad_R3.indd 1 12/2/20 3:43 pm
Abstracts Oral Presentations Standard Oral Rapid Fire New Investigator Dr Afaf Abed - Genomic HLA as a predictive marker for overall survival Prof Michael Macmanus - What proportion of patients commence in non-small cell lung cancer patients post immunotherapy but fail to complete curative-intent chemoradiotherapy for non-small Dr Surein Arulananda - BCL-XL inhibition in combination with cisplatin cell lung cancer? is effective in malignant pleural mesothelioma due to its dependency Dr Lin Mo - The international lung screen trial: Results from three on the BCL-XL pro-survival protein Australian sites Prof Fraser Brims - Targeted lung cancer screening in Australia: is there Ms Kirsten Mooney - Harnessing innovation to improve outcomes a need to account for asbestos exposure? for lung cancer patients: Proof of concept for prehabilitation within a Dr Kim-lin Chiew - A future role for quality indicators in lung cancer tertiary hospital. multidisciplinary teams Mr Preston Ngo - Real-world treatment patterns for lung cancer: Miss Vrushali Chimankar - Can genomic sequencing on mouse model Systemic therapy utilisation and factors relating to treatment in of lung cancer help us to understand the genetics of human lung Australia cancer? Prof Nir Peled - Pembrolizumab plus Chemotherapy for advanced Dr Venessa Chin - Single-cell transcriptomics and proteomics to assess NSCLC without tumor PD-L1 expression: Pooled analysis of KEYNOTE- response to immunotherapy in real-time 021G, KEYNOTE-189 and KEYNOTE-407 Ms Vivienne Chipman - Building health literacy among culturally and Dr Jonathan Pham - Excess mortality in elderly patients diagnosed linguistically diverse Australians affected by lung cancer with advanced lung cancer is related to under-prescribing of active treatments, after controlling for confounders Dr Laura Croft - A first in class DNA repair inhibitor for the treatment of lung cancer Dr Hema Ramarmuty - Convex probe EBUS bronchoscopy guided placement of fiducial marker in oligo-metastatic mediastinal lymph Dr Paul Dawkins - Development of national quality performance nodes for cyberKnife stereotactic body radiotherapy – Safety and indicators for lung cancer in New Zealand feasibility Tracey Guan - QOOL-Dash: converting data to accessible information Dr Nicole Rankin - The potential for implementation of LDCT lung for real-time monitoring of lung cancer outcomes for patients reviewed cancer screening in the Australian setting: outcomes of an evidence at MDT in Queensland check review Dr Pei Ding - Plasma ctDNA T790M mutation load predicts response Miss Katherine Bahar Sahin - Evaluation of AURKA inhibition as a to second line Osimertinib in patients with advanced epidermal growth novel strategy to improve EGFR-mutant tumour response to tyrosine factor receptor mutant non-small cell lung cancer: An Australian kinase inhibitors multicentre retrospective study Miss Priyanka Sahu - Novel mouse model for investigating the Dr Lara Edbrooke - Physical activity levels are low in people with pathogenesis of early stage squamous cell lung carcinoma inoperable lung cancer A/Prof Jasotha Sanmugarajah - 30-day mortality following Dr Samantha Ennis - Extent of emphysema in low dose CT scans intravenous systemic therapy for non-small cell lung cancer patients performed for lung cancer screening in an Australian cohort in Queensland Dr Fanny Franchini - Patterns of care in never-smokers versus smokers Dr Matthew Soeberg - Lung cancer and its association with asbestosis in the treatment of lung cancer mortality: What can we find out from Australia’s cause of death data Dr Marina Chiara Garassino - PD-L1 expression, patterns of progression Dr Emily Stone - ILST Australia: Impact of recruitment strategy and patient-reported outcomes with Durvalumab plus Platinum- on eligibility rates for LDCT lung cancer screening at baseline in an Etoposide in extensive-stage small-cell lung cancer: Results from the Australian centre randomised, controlled, open label phase 3 CASPIAN trial Dr Emily Stone - ILST (International Lung Screen Trial) Australia: Dr Daryn Goodwin - The use of next generation sequencing in the Baseline results at an Australian trial centre for low dose CT screening characterisation of multiple primary lung cancers for lung cancer Dr Daniel Gough - STAT3 deletion increases metastatic small cell lung Dr Amila Suraweera - Defining a novel DNA repair protein as an anti- cancer cancer therapeutic target in non-small cell lung cancer Dr Susan Harden - Utilising a national clinical quality registry to drive Dr Kate Sutherland - Harnessing natural killer immunity in metastatic improvement in lung cancer outcomes: Radiation oncology examples small cell lung cancer from the UK National Lung Cancer Audit Ms Louise Underhill - “Hanging on the telephone” – measuring the Prof Rina Hui - KEYNOTE-024 3-year survival update: Pembrolizumab impact of a telephone-based specialist lung cancer nursing service vs Platinum-Based Chemotherapy for advanced non-small cell lung cancer Dr Stephen Wade - Estimated smoking rates over the next 50 years in Australia Ms Elena Jensen-Marini - Exploring patient reported quality of life in lung cancer patients: A qualitative study Dr Marianne Weber - Estimated risk for lung cancer incidence and mortality related to tobacco smoking among 229,028 Australians A/Prof Tom John - Osimertinib vs comparator EGFR-TKI as first-line treatment for EGFRm advanced non-small cell lung cancer (FLAURA): Tracey Guan - Lung cancer clinical practice indicators for Queensland: Final overall survival analysis A work in progress Dr Kuan Pin Lim - Comparing recruitment strategies in lung cancer A/Prof Jasotha Sanmugarajah - Timely lung cancer care is influenced screening: GP-based mail-outs or population-based mail-outs? by stage at diagnosis, a population-wide study from Queensland Dr Patrick MaClean - Influence of the time interval from diagnosis to Mrs Hui You - Patterns of treatment and survival for people with small treatment on survival for early-stage non-small cell lung cancer cell lung cancer in NSW 26 Australian Lung Cancer Conference 2020 Handbook
How can you support us? Invest in the Future Scientific breakthroughs can take years to accomplish. Invest in a future free from lung disease by leaving a bequest or gift as part of your Will. Leaving a bequest is a way of ensuring you can continue to support the causes that are special to you, even after you’re gone. Equally, talking with your family about a Gift in Memoriam celebrates your life and gives hope to others. Help Find a Cure Your donation can help us understand the causes and future treatments of lung disease. Regular giving is our most precious source of revenue. It gives us certainty and continuity in an unpredictable funding environment and provides an independent source of funding. A donation of $5.00 per week goes a long way. Put simply regular donations allow great science to flourish. Get Involved More than ever, Australians are aware of the need to increase research funding to fight lung disease and give hope to their fellow Australians. Share your story, become a Lung Foundation Australia Ambassador or join workplace giving. There are many ways you can support Lung Foundation Australia and make a difference. Philanthropy and Partnerships Lung Foundation Australia is proud to partner with philanthropists, companies, trusts and foundations to raise vital funds for lung disease research. We focus on forming personalised connections with donors and supporters to achieve our mission. We are outcomes focused and ensure your investment is tracked against measurable goals. As with all our support, we keep you up-to-date on progress. This is our promise. Community Fundraising Celebrate hope and support your loved one, friend or work colleague by doing something you love. Join our team, take part in a fun run, cycle or hold an event.
You can also read