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LIFE
SCIENCES
2022
AVA I L A B L E I N P R I N T A N D D I G I TA L
M O R E D I G I TA L P R O D U C T S O N W O R L D S C I N E T
Highlights Life Sciences Catalogue 2022
page 4 page 4 page 4 page 6
by Don Kulasiri (Lincoln edited by Thomas Ming Swi edited by Kurt Wüthrich by Zheng Rong Yang
University, New Zealand) Chang (McGill University, (ETH Zürich, Switzerland (University of Exeter, UK)
& Jingyi Liang Canada & Shenzhen & The Scripps Research
(UiT The Arctic University of University, China & Shantou Institute, USA)
Norway, Norway) University, China), et. al.
page 7 page 7 page 9 page 11
by Mark I M Noble by Benoit Roux edited by Stephen S Hecht by Dianliang Wang
(University of Aberdeen, UK) (The University of (University of Minnesota, (China Association for Science
Chicago, USA) Twin Cities, USA) & Dorothy and Technology, China) &
K Hatsukami (University of Haijia Chen (Guangzhou
Minnesota, Twin Cities, USA) Saliai Stem Cell Science and
Technology Co., Ltd., China)
page 11 page 14 page 14 page 15
by Charles DeLisi by Dunne Fong edited by Adrien A Eshraghi by Thomas R Platt
(Boston University, USA) (Rutgers, The State (University of Miami, USA) (Saint Mary’s College,
University of New Jersey, Notre Dame, USA)
USA) & Marion M Chan
(Temple University, USA)
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Life Sciences Catalogue 2022
BIOCHEMISTRY
ALZHEIMER’S DISEASE WATER AND LIFE
Biology, Biophysics and Computational Life in Water and Water in Life
Models by Arieh Ben-Naim (The Hebrew University
by Don Kulasiri (Lincoln University, of Jerusalem, Israel), Zvi Kirson (The Hebrew
New Zealand) & Jingyi Liang (UiT University of Jerusalem, Israel) &
The Arctic University of Norway, Norway) Jose Angel Sordo (University of Oveido,
Spain)
Alzheimer’s Disease: Biology, Biophysics
and Computational Models help the reader This book is unique in presenting all aspects
to understand AD from mechanistic and of water. It includes discussion of the theory
biochemical perspectives at intra- and inter- of a water molecule, its properties, both in
cellular levels. It focuses on biochemical the pure state and as a solvent. In particular,
pathways and modeling associated with AD. Some of the recent research it emphasizes the relevance of water to life.
on biophysics and computational models related to AD are explained using Water is the most important liquid. It is also a vital component of all living
context-driven computational and mathematical modeling and essential systems. It has very unusual properties which makes it the most interesting
biology is discussed to understand the modeling research. for research and study.
480pp Aug 2021 284pp Mar 2021
978-1-80061-011-8 US$158 £140 978-981-122-550-5 US$88 £75
Regenerative Medicine, Artificial Cells and
Nanomedicine – Volume 6 UNTANGLING
NANOBIOTHERAPEUTIC MOLECULAR DIVERSITY
Explaining Unity and Diversity Principles
BASED BLOOD of Organization with Molecular Structure
SUBSTITUES and Evolutionary Genomics
edited by Thomas Ming Swi Chang (McGill edited by Gustavo Caetano-Anolles
University, Canada & Shenzhen University, (University of Illinois at Urbana-Champaign,
China & Shantou University, China), et. al. USA)
This definitive volume will provide the reader Untangling Molecular Biodiversity presents a
with up to date information and the most recent unique global framework to explain molecular
science of the fast-evolving area of nanobiotherapeutic-based blood and organismal biodiversity that is grounded in
substitutes. Long studied, there are recent updates that make their use in evolutionary genomics. This book will tackle important questions such as
patients more promising, and with one product approved for human use, the origin of life, the emergence of biochemistry, the origin of viruses, the
many more in the pipeline. These include 2nd generations and even third nature of the last universal common ancestor responsible for diversified
generation ones, the later with enhancement of red blood cell functions. In life, the role of information and thermodynamics in evolution, the reason for
addition, there are carefully written and referenced updates on the recent having three cellular domains in life, and the centrality of modules in biology.
history and products in the field, complete with pathophysiologic and
672pp Nov 2020
pharmacologic studies to validate and verify the efficacy and safety of many
978-981-4656-61-0 US$188 £165
of these new products.
650pp Aug 2021
978-981-122-868-1 US$178 £155 Series in Structural Biology – Volume 12
STRUCTURAL INSIGHTS
INTO GENE EXPRESSION
NMR WITH BIOLOGICAL
AND PROTEIN SYNTHESIS
MACROMOLECULES IN by Thomas A Steitz (Yale University, USA)
4
SOLUTION Thomas Steitz is best known for the work he and
A Selection of Papers Published from
his coworkers did to elucidate the biochemical
1996 to 2020 by Kurt Wüthrich
basis of gene expression. The structures of a
edited by Kurt Wüthrich (ETH Zürich,
Switzerland & The Scripps Research large number of the macromolecules involved in
Institute, USA) transcription and translation emerged from his
laboratory over the course of his career. This book includes reprints of the
The book provides insights into the research of most important papers he had published, grouped according to the structures
the Kurt Wüthrich laboratories from 1996–2020. they relate to, and commentaries written by the scientists who collaborated
During this time period, the technique of with him to solve each of them. It thus summarizes the achievements of one
nuclear magnetic resonance (NMR) spectroscopy in solution went through of the most distinguished biochemists of the second half of the 20th century.
several breakthroughs, while maturing into a standard method of structural
biology. With the introduction of TROSY (transverse relaxation-optimized 640pp Aug 2020
spectroscopy), the range of accessible molecular sizes was extended about 978-981-121-585-8 US$198 £175
thirty-fold, and efficient protein structure determination resulted from the
demands of the structural genomics initiative.
264pp Jul 2021
978-981-123-578-8 US$128 £115
978-981-123-913-7(pbk) US$58 £50
For more information, visit: www.worldscientific.com WORLD SCIENTIFIC
BIOENGINEERING BIOSTATISTICS
ARTIFICIAL INTELLIGENCE MEDICAL STATISTICS
PLATFORM FOR A Practical Approach
by Tze-San Lee (Western Illinois University,
MOLECULAR TARGETED USA)
THEORY This book is more modern than the current
A Translational Science Appraoch textbook in medical statistics. In this book,
by Ariel Fernandez (Former Hassleman biostatistics and epidemiologic concepts are
Professor of Bioengineering, Rice University, nicely blended. In contrast to the fallacy of
USA & CONICET, National Research the p-value, it introduces the Bayes factor
Council, Argentina) as a measure of the evidence hidden in the
“This is an excellent book. AI is taking the sample data. It illustrates the application of
world by storm, and this book will help to pave the way for serious the regression to the mean in medicine. Many epidemiologic concepts
applications of AI in drug design. Fernandez has extensive experience such as sensitivity and specificity of the diagnostic test, classification and
in the field including multiple patents based on his work on wrapping discrimination, types of bias, etc. are discussed in the book.
technology. He proposes to integrate this experience with leading AI In addition, advanced techniques in comparing two survival curves are
platforms to show how they can be used in drug design. I think the included in the book such as Armitage’s preference method, Armitage’s
book will be very popular with anyone involved in drug design and in restricted sequential test and Wald’s sequential sign test. Also, inference on
biochemistry more broadly.” contingency tables are treated in more detail than other books.
Ridgway Scott, The University of Chicago, USA
428pp Jan 2021
468pp Mar 2021 978-981-121-751-7 US$118 £105
978-981-123-230-5 US$148 £130 978-981-121-842-2(pbk) US$58 £50
GENES, GERMS AND
MEDICINE STATISTICAL METHODS
The Life of Joshua Lederberg FOR BIOMEDICAL
by Jan Sapp (York University, Canada) RESEARCH
Joshua Lederberg was a scientific renaissance by Jiqian Fang (Sun Yat-sen University, China)
man. He and his collaborators founded the This book consists of four parts with 32 chapters
field of bacterial genetics, and he was awarded adapted for four short courses, from the basic
the Nobel Prize at the age of 33 (the second to the advanced levels of medical statistics
youngest in history). He helped to lay the (biostatistics), ideal for biomedical students.
foundations for genetic engineering, made Part 1 is a compulsory course of Basic Statistics
fundamental revisions to immunological and with descriptive statistics, parameter estimation
evolutionary theory, and developed medical genetics. He initiated the and hypothesis test, simple correlation and
search for extraterrestrial microbial life, developed artificial intelligence, and regression. Part 2 is a selective course on Study Design and Implementation
was a visionary of the Digital Age. Lederberg coined some of the central with sampling survey, interventional study, observational study, diagnosis
terms of modern biology: plasmid, transduction, exobiology, euphenics study, data sorting and article writing. Part 3 is a specially curated course
and microbiome. of Multivariate Analyses with complex analyses of variance, variety of
regressions and classical multivariate analyses. Part 4 is a seminar course
424pp Feb 2021
on Introduction to Advanced Statistical Methods with meta-analysis, time
978-981-122-547-5 US$98 £85
series, item response theory, structure equation model, multi-level model,
978-981-123-598-6(pbk) US$38 £35 bio-informatics, genetic statistics and data mining.
1160pp Mar 2021
Submit your paper to this journal. 978-981-122-886-5 US$238 £210
Recommend this journal to your librarian!
For a free institutional trial or subscribe to this journal,
please contact us at sales@wspc.com CROP SCIENCE 5
JOURNAL OF MECHANICS IN
MEDICINE AND BIOLOGY (JMMB) THE NINTH REVOLUTION
The first Journal to Publish Original Research Articles Transforming Food Systems for Good
by Sayed Nader Azam-Ali (Crops for the
in ALL Fields of Mechanics in Medicine and Biology
Future, UK)
https://www.worldscientific.com/jmmb
We are at a critical point in human history and
Impact Factor: 0.897 that of the planet. In this book, a world leader
This journal has as its objective the publication in agricultural research, the author proposes a
and dissemination of original research (even radical transformation of our agrifood system.
for “revolutionary concepts that contrast with He argues that agriculture must be understood
existing theories” & “hypothesis”) in all fields
of engineering-mechanics that includes as part of global biodiversity and that food
mechanisms, processes, bio-sensors and bio- systems have cultural, nutritional, and social
devices in medicine, biology and healthcare. values beyond market price alone. The book concludes with a call to
The journal publishes original papers in action in which diversification of species, systems, knowledge, cultures,
English which contribute to an understanding and products all contribute to The Ninth Revolution that will transform food
of biomedical engineering and science at systems for good.
a nano- to macro-scale or an improvement
of the methods and techniques of medical, 400pp Jun 2021
biological and clinical treatment by the 978-981-123-644-0 US$128 £115
application of advanced high technology.
978-981-125-010-1(pbk) US$34.95 £30Life Sciences Catalogue 2022
BIOINFORMATICS FROM FRACTCAL AND
CELLULAR AUTOMATA
TO BIOLOGY
BIOLOGICAL PATTERN Information as Order Hidden with Chance
DISCOVERY WITH R by Alberto Strumia (Isituto Nazionale di
Machine Learning Approaches Alta Matematica “Francesco Severi”, Italy)
by Zheng Rong Yang (University of Exeter, UK)
The didactical level of exposition, together
This book provides the research directions for with many astonishing images and animations,
new or junior researchers who are going to use accompanied by the related simple computer
machine learning approaches for biological programming codes (in Python and POV-Ray
pattern discovery. The book was written based languages) make this book an extremely and unique useful tool to test the
on the research experience of the author’s power of algorithmic information in generating ordered structure models (2D
several research projects in collaboration with and 3D) like regular geometric shapes, complex shapes like fractals and
biologists worldwide. The chapters are organised cellular automata, and biological systems as the organs of a living body.
to address individual biological pattern discovery problems. For each subject,
the research methodologies and the machine learning algorithms which 328pp Jul 2020
can be employed are introduced and compared. Importantly, each chapter 978-981-121-715-9 US$138 £120
was written with the aim to help the readers to transfer their knowledge in
theory to practical implementation smoothly.
PROTEIN INTERACTIONS
400pp Nov 2021 Computational Methods, Analysis and
978-981-124-011-9 US$118 £105 Applications
edited by M Michael Gromiha
(Indian Institute of Technology Madras, India)
ARTIFICIAL INTELLIGENCE
“This book provides a wide coverage of the
APPLICATIONS IN HUMAN recent advances in the protein interactions
PATHOLOGY analysis and their applications. It brings
edited by Ralf Huss (University Hospital together the descriptions of the state-of-the-
Augsburg, Germany) & Michael Grunkin art computational tools available to solve
(Visiopharm, Denmark) biological research problems. It is a valuable
Advances in machine learning and AI in general resource for the researchers, postgraduate students and others
have propelled computational and general working in the field of Bioinformatics.”
pathology research. Today, computer systems Professor K Ramanathan
approach the diagnostic levels achieved SBST, VIT University, India
by humans for certain well-defined tasks in 424pp Mar 2020
pathology. The book deals with the latest topics in biomedical research and 978-981-121-186-7 US$148 £130
clinical cancer diagnostics. With chapters provided by true international
experts in the field, this book gives real examples of the implementation of
AI and machine learning in human pathology. Submit your paper to this journal.
Recommend this journal to your librarian!
216pp Dec 2021
978-1-80061-138-2 US$78 £70 For a free institutional trial or subscribe to this journal,
please contact us at sales@wspc.com
A TEXTBOOK OF JOURNAL OF BIOINFORMATICS AND
BIOINFORMATICS COMPUTATIONAL BIOLOGY (JBCB)
Information-theoretic Perspectives of https://www.worldscientific.com/jbcb
Bioengineering and Biological Complexes
by Perambur S Neelakanta
Impact Factor: 1.122
6 (Florida Atlantic University, USA) This journal aims to publish high quality,
original research articles, expository tutorial
This book on bioinformatics is designed as
papers and review papers as well as short,
an introduction to the conventional details of critical comments on technical issues
genomics and proteomics as well as a practical associated with the analysis of cellular
comprehension text with an extended scope on information. Check out the
the state-of-the-art bioinformatic details pertinent FREE articles
to next-generation sequencing, translational/clinical bioinformatics and The research papers will be technical
online!
vaccine-design related viral informatics. The book is aimed at students, presentations of new assertions, discoveries
and tools, intended for a narrower specialist
faculty and researchers in biology, health/medical sciences, veterinary/
community. The tutorials, reviews and critical
agricultural sciences, bioengineering, biotechnology and genetic
commentary will be targeted at a broader
engineering. It will be a useful companion for managerial personnel in the
readership of biologists who are interested in
biotechnology and bioengineering industries as well as in health/medical
using computers but are not knowledgeable about scientific computing,
science. and equally, computer scientists who have an interest in biology but
684pp Aug 2020 are not familiar with current thrusts nor the language of biology. Such
978-981-121-288-8 US$168 £150 carefully chosen tutorials and articles should greatly accelerate the rate
of entry of these new creative scientists into the field.
From June 2021, the Journal of Bioinformatics and Computational
Textbook: Request Inspection Biology also considers in silico studies of exceptional merits.
Copy at sales@wspc.com *Please log in to your existing account or register for a
or scan the QR code FREE account to enjoy FREE access to the selected articles.For more information, visit: www.worldscientific.com WORLD SCIENTIFIC
BIOMEDICAL SCIENCES BIOPHYSICS
CELL-FREE CIRCULATING DNA CHAOTIC DNA DYNAMICS
Purification and Analysis Techniques by Amujuri Mary Selvam (Indian Institute
by Daniel Branton (Harvard University, USA) & of Tropical Meterology, India)
David Deamer (University of California Santa Cruz, USA)
A general systems theory model predicts
Cell-free circulating DNA is found in blood plasma, and is not associated with quasiperiodic Penrose tiling pattern for the
any cell fraction. While the origin and biological function of cell-free DNA is nested coiled structure of the DNA molecule
poorly understood, it has many potential clinical applications. In pregnant in the chromosome resulting in maximum
women, a fraction of the cell-free DNA is of fetal origin and forms the basis of packing efficiency and unified whole fuzzy logic
Non-Invasive Pre-natal Testing (NIPT). NIPT has been a tremendous clinical network architecture with ordered two-way
and commercial success, replacing previously established diagnostic tests signal transmission between the coding and
and decreasing the number of unnecessary invasive procedures. non-coding (junk DNA) regions.
The aims of the book are to bring together expertise in working with Junk DNA are not redundant. Modification of the DNA base sequence
circulating DNA from blood, and systematically address technical aspects structure at any location may have significant noticeable effects on the
of each step from blood collection through DNA purification and analysis, as function of the DNA molecule as a whole. This book helps us understand the
well as commercial considerations for circulating DNA-based diagnostics. cooperative existence of individual components for optimum performance
Since circulating DNA offers non-invasive ‘liquid biopsy’ access to the cancer of the system.
genome, there has been a great deal of excitement in both academic and
commercial spheres about its use it for diagnostic applications in cancer. 200pp Dec 2021
978-981-124-285-4 US$88 £75
300pp Jan 2022
978-981-124-467-4 US$118 £105
ELECTROMAGNETISM,
QUANTA, AND
EMERGING TECHNOLOGIES ELECTRON FLOW IN THE
IN BIOPHYSICAL SCIENCES: ELECTROPHYSIOLOGY
A WORLD SCIENTIFIC OF LIVING CELLS
REFERENCE by Mark I M Noble (University of Aberdeen, UK)
(In 3 Volumes) “Mark Noble has had a long and distinguished
Volume 1: Emerging Technologies for career in academic and cardiac medicine
Biofabrication and Biomanufacturing ... much of which has focussed on
Volume 2: Emerging Technologies electrophysiological mechanisms controlling
for Fertility Volume 3: Emerging rate, rhythm and contractile behaviour in the heart. This book, which
Technologies for Diagnostics draws on reflections in his retirement, is a fascinating and iconoclastic
Volume editors: Utkan Demirci (Stanford University, USA), survey of electrophysiological processes in both cardiac and many other
Rami El Assal (Stanford University, USA), Pu Chen (Wuhan excitable tissues in the animal kingdom which will interest and alter the
University, China) & Waseem Asghar understanding of both clinicians and basic scientists in many disciplines.”
Editor-in-chief: Utkan Demirci (Stanford University, USA) Anthony Seed
Emeritus Professor, Imperial College London, UK
Biofabrication aims to produce artificially manufactured tissues and organs,
potentially revolutionizing conventional paradigm of clinical practice in 200pp Nov 2021
treating diseases and extending the life span and quality of human beings. 978-981-123-494-1 US$88 £75
In this volume, we invite notable experts in the field of biofabrication and
biomanufacturing to summarize recent rapid progress in this field from
multifaceted aspects covering biofabrication techniques and building COMPUTATIONAL
materials such as scaffold and living cells. MODELING AND 7
1050pp Nov 2021 SIMULATIONS OF
978-981-122-565-9 (SET) US$1200 £1055 BIOMOLECULAR SYSTEMS
Introductory Offer till US$880 £775 Simulations of Biomolecular Systems
Mar 31, 2022 by Benoit Roux (The University of
Chicago, USA)
This textbook originated from the course
“Simulation, Modeling, and Computations in
Biophysics” that I have taught at the University
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of backgrounds, including biology, physics, chemistry, biochemistry,
and mathematics, and the course was intentionally adapted for senior
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to represent the function of large biological macromolecular machines.
Sign up now @
www.worldscientific.com/page/newsletter/subscribe 200pp Aug 2021
978-981-123-275-6 US$88 £75Life Sciences Catalogue 2022
THE PHYSICS OF CANCER MACROALGAL
Research Advances BIOREFINERIES FOR THE
edited by Bernard S Gerstman
(Florida International Univeristy, USA) BLUE ECONOMY
by Alexander Golberg (Tel Aviv University,
In the case of cancer, controlling the system’s Israel), Arthur Nils Robin (Tel Aviv University,
behavior will mean the ability to treat and cure Israel), Meiron Zollmann (Tel Aviv University,
the disease. Physicists have been studying Israel), Hadar Traugott (Tel Aviv University,
various complex, nonlinear systems for many Israel), Ruslana Rachel Palatnik (University
years using a variety of techniques. These of Haifa, Israel) & Alvaro Israel (Israel
Oceanographic & Limnological Research
investigations have provided insights that
Institute, Israel)
allow physicists to make unique contributions
towards the treatment of cancer. This interdisciplinary book presents recent This unique compendium provides an insight into the role of emerging
advancements in physicists’ research on cancer. The work presented in this marine biorefineries based on macroalgae (seaweeds) in the development
volume uses a variety of physical, biochemical, mathematical, theoretical, of a sustainable use of ocean resources for economic growth-blue economy.
and computational techniques to gain a deeper molecular and cellular
The useful reference text shows a complete picture on the motivation
understanding of the horrific disease that is cancer.
to develop seaweed technologies, and how the combination of biology,
280pp Dec 2020 cultivation technologies and downstream processing with economics can
978-981-122-348-8 US$88 £75 address the social challenges through the blue growth.
304pp Nov 2020
978-981-122-428-7 US$108 £95
MOLECULAR IMAGING
Basic Principles and Applications in
Biomedical Research
(3rd Edition) Submit your paper to this journal.
by Markus Rudin (University of Zurich,
Switzerland & ETH Zurich, Switzerland)
Recommend this journal to your librarian!
This volume familiarizes the reader with the For a free institutional trial or subscribe to this journal,
concepts of imaging and molecular imaging please contact us at sales@wspc.com
in particular. Basic principles of imaging
technologies, reporter moieties for the various JOURNAL OF COMPUTATIONAL
imaging modalities, and the design of targeted BIOPHYSICS AND CHEMISTRY (JCBC)
probes are described in the first part. The second part illustrates how Formerly known as Journal of Theoretical and
these tools can be used to visualize relevant molecular events in the living Computational Chemistry
organism. Topics covered include the studies of the biodistribution of reporter
probes and drugs, visualization of the expression of biomolecules such https://www.worldscientific.com/jbcb
as receptors and enzymes, and how imaging can be used for analyzing
consequences of the interaction of a ligand or a drug with its molecular target Impact Factor: increased 11% to 0.939
by visualizing signal transduction, or assessing the metabolic, physiological,
The journal publishes original contributions
or structural response of the organism studied.
on broad aspects: from both the develop-
800pp Apr 2020 ment of fundamental theoretical methodolo-
978-1-78634-684-1 US$178 £155 gy and computational algorithm to extensive
numerical applications to specific scientific
problems ranging from gas-phase to con-
densed phase, and to biological systems.
BIOTECHNOLOGY It covers general research areas broadly
defined as quantum chemistry, chemical
dynamics, statistical mechanics, and chemi-
8
ORCHID BIOTEHCNOLOGY IV cal biology.
edited by Wen-Huei Chen (National Cheng
Kung University, Taiwan) & Hong-Hwa Chen *Please log in to your existing account or register for a
(National Cheng Kung University, Taiwan) FREE account to enjoy FREE access to the selected articles.
Orchid Biotechnology IV presents a series
of recent work on both basic and applied
researches in biotechnology progress for
Phalaenopsis, Oncidium and Erycina pusila
orchids. These include breeding of Phalaenopsis
orchids of black flower, big-white flower and
small and floriferous flowers, physiology for
shipping and photosynthesis, SSR markers and mitochondrial DNA markers,
virus detection and antiviral immunity, embyogenesis and relationship with
mycorrhiza symbiosis, transposon and retrotransposon, orchid genome
and evolution, regulation of orchid floral scent, floral color modification, and
abiotic stress tolerance.
452pp Mar 2021
978-981-121-776-0 US$168 £150For more information, visit: www.worldscientific.com WORLD SCIENTIFIC
CANCER RESEARCH TRIPLE-NEGATIVE BREAST
CANCER
edited by Xiyun Deng (Hunan Normal
CIRCULATING TUMOR CELLS University School of Medicine, China),
by Gary A Clawson (Pennsylvania State University, USA) Faqing Tang (Hunan Cancer Hospital, China),
Thomas J Rosol (Ohio University Heritage
This book is designed to give a comprehensive overview of the field of College of Osteopathic Medicine, USA)
Circulating Tumor Cells (CTCs), which are found in blood of patients with
cancer. It includes descriptions of basic techniques used to capture and Triple-negative breast cancer (TNBC) represents
quantify CTCs, and methods employed to propagate them after capture for a challenge clinically due to the lack of actionable
downstream study. An overview of various molecular approaches for CTC targets coupled with an aggressive disease
analysis and characterizations is provided, including their applicability as a course and a worse prognosis compared to other
“liquid biopsy” and their potential utility for predicting therapeutic response to breast cancer subtypes. This book covers aspects of TNBC ranging from
treatments. A number of aspects involved in the metastatic spread of cancer epidemiology, biology, molecular classification, to currently available and
are also discussed, as well as how quantitation and characteristics of CTCs potentially new therapeutic options for TNBC. This book contains a range of
relate to what is known about the metastatic cascade. recommended resources, including recent reviews, schematic illustrations,
and information for patients with TNBC. Individuals including researchers
300pp Dec 2022 and educators, practitioners, pharmaceutical professionals, patients as well
978-981-120-665-8 US$118 £105 as their family members will find this book useful.
248pp Oct 2020
TOBACCO AND CANCER 978-981-3277-75-5 US$88 £75
The Science and the Story
edited by Stephen S Hecht (University of
Minnesota, Twin Cities, USA) & Dorothy K Submit your paper to these journals.
Hatsukami (University of Minnesota,
Twin Cities, USA)
Recommend them to your librarian!
For a free institutional trial or subscribe to these journals,
This book tells the fascinating story of the
please contact us at sales@wspc.com
relationship of tobacco products to cancer,
from the first discoveries to the present day
cancer pandemic and regulatory activities.
BIOMEDICAL ENGINEERING:
Although there are already excellent books and APPLICATIONS, BASIS AND
monographs on this topic, both in the popular press and as government COMMUNICATIONS (BME)
summaries, none relate the scientific story at the level of non-specialist https://www.worldscientific.com/bme
graduate and medical students, researchers, or educated popular science
readers. In this book, with a primary focus on the United States, the editors Biomedical Engineering: Applications,
— Stephen S Hecht and Dorothy K Hatsukami — bring together 24 renowned Basis and Communications is an inter-
national, interdisciplinary journal aiming
experts on the subject of tobacco and cancer to summarize specific aspects
at publishing up-to-date contributions
of this critical topic in relatively non-technical terms while also incorporating
on original clinical and basic research in
some personal insights related to the story of the discovery process. This Check out the
the biomedical engineering. Research of
highly authoritative book is also expected to be an excellent teaching tool and FREE articles
biomedical engineering has grown tremen-
basis for a course for graduate and medical students on this important topic. online!
dously in the past few decades. Meanwhile,
400pp Oct 2021 several outstanding journals in the field
978-981-123-952-6 US$118 £105 have emerged, with different emphases
and objectives. We hope this journal will
serve as a new forum for both scientists
and clinicians to share their ideas and the results of their studies.
CELL MECHANICS AND
TUMOR DEVELOPMENT
by Ronald L Huston INNOVATION
(University of Cincinnati, USA) AND EMERGING 9
The focus of this book is on centrioles — small TECHNOLOGIES
organelles adjacent to the nucleus in all human An International Journal on Innovative
and animal (eucaryotic) cells. It provides the Applied Sciences, Engineering and
findings and critical analyses of over 750 articles Biomedical Research
written in this century. Formerly known as TECHNOLOGY
In addition to centrioles, the topics include: https://www.worldscientific.com/iet
centrosomes, chromosomes, microtubules and kinetochores, cell division
Fashioned as a high-impact, high-visibility,
and duplication, and tumor development. The book also includes discussions
top-echelon publication, this new ground-breaking journal - Innovation
on centriole dynamics and electromagnetics effects. It concludes with a and Emerging Technologies - will feature the development of cutting-
chapter on centriole errors — particularly cells with supernumerary centrioles. edge new technologies in a broad array of emerging fields of science
The book is intended for students, scholars, and researchers studying and and engineering. The content will have an applied science and
working in the field of nuclear mechanics. In addition to the book content, it technological slant with a focus on both innovation and application
provides a guide for literature investigation. to daily lives. It will cover diverse disciplines such as health and life
science, energy and environment, advanced materials, technology-
460pp Feb 2020 based manufacturing, information science and technology, and marine
978-981-120-894-2 US$148 £130 and transportations technologies.
*Please log in to your existing account or register for a
FREE account to enjoy FREE access to the selected articles.Life Sciences Catalogue 2022
CELL / MOLECULAR BIOLOGY
NON-COVALENT WALTER GILBERT
INTERACTIONS IN Selected Works
by Walter Gilbert (Harvard university, USA)
PROTEINS edited by Manyuan Long (The University of
(2nd Edition) Chicago, USA)
by Andrey Karshikoff (Bulgarian Academy
of Sciences, Bulgaria) This book commemorates the eclectic
intellectual life of scientist and artist Walter
This second edition includes new chapters on
intrinsically disordered proteins, microcalorimetry Gilbert. It presents all of his most influential
of proteins, cold denaturation, thermodynamic works throughout his scientific career. His
stability and thermal adaptability of proteins. The scientific explorations covered a broad spectrum
ideal aid for students of physics or chemistry, with interests in biology and of fields: theoretical physics; molecular biology,
biophysics, the book can also be useful for students of biology, biochemistry, from finding messenger RNA to elucidating the regulation of the lac operon
or biomedicine who want to extend their knowledge of how protein properties to understanding DNA replication; gene evolution and origin of life; genomics;
are described at the molecular level. bioinformatics; and beyond. He created widely used concepts such as
“Exon”, “Intron” and “RNA World”. Eleven reflective essays by Gilbert are
400pp Aug 2021
included for the first time, discussing both his scientific studies and anecdotes
978-981-122-808-7 US$148 £130
from his own life.
616pp Feb 2020
REPLICATING AND 978-981-120-329-9 US$198 £175
REPAIRING THE GENOME
From Basic Mechanisms to Modern
Genetic Technologies CAUGHT BY VIRUSES
by Kenneth N Kreuzer (Duke Univ., USA) by Michael G Rossmann
Replicating and Repairing the Genome provides The current book attempts to give a glimpse
a concise overview of the fields of DNA of the scientific life of Michael Rossmann. The
replication and repair. The book is particularly book begins with his very interesting and moving
appropriate for graduate students and advanced autobiography.
undergraduates, and scientists entering the With an interest in symmetry, viruses became
field or working in related fields. The breadth of obvious objects to study. Rossmann attacked
information regarding DNA replication and repair is vast and often difficult to these monstrously large molecular assemblies
absorb, with terminology that differs between experimental systems and with with his unfailing energy and his appetite for
complex interconnections of these processes with other cellular pathways. real challenges. The amazing variation of molecular arrangements with
This book provides simple conceptual descriptions of replication and repair icosahedral symmetry is truly amazing. This book includes a selection
pathways using mostly generic protein names, laying out the logic for how of reports of the structures of some giant viruses. As always, knowing
the pathways function and highlighting fascinating aspects of the underlying the structure enhances the understanding of function greatly, in the case
biochemical mechanisms and biology. of viruses the mechanism of infection is a key problem. Rossmann has
400pp Mar 2020 contributed many central insights in this area.
978-981-121-569-8 US$118 £105 275pp Oct 2021
978-981-124-619-7 US$88 £75
HEME BIOLOGY
Heme Acts as a Versatile Signaling
Molecule Regulating Diverse Biological COGNITIVE SCIENCE
Processes (2nd Edition)
10 edited by Li Zhang (The University of
Texas at Dallas, USA)
FINDING PLACES
The Search for the Brain’s GPS
This invaluable book provides the first description by Unni Eikeseth (Norwegian University of
of the diverse and fascinating functions of heme Science and Technology, Norway)
in life processes for a broad audience. It begins translated by Lucy Moffatt
with an introduction of the intricate chemical
properties of heme and the history of early Finding Places tells the story of the ground-
observations of human diseases associated with heme. It then proceeds breaking discovery of the cells that constitute the
to describe the versatile roles of heme in controlling diverse molecular and brain’s positioning system — its GPS. The book
cellular processes germane to human life and disease processes. takes you into the lab of neuroscientists May-
Britt and Edvard Moser and lets you experience
Heme Biology is unified and logical in presentation. It is well suited for the work of the many researchers who revealed
students and professionals in life sciences who wish to know about the how certain incredible cells help rats and humans find their way. It details
fascinating biology of heme and its usefulness in health and diseases. It may the discovery of the mind-boggling “grid cells”, which generate a hexagonal
also be used as a reference book for advanced readers and researchers who coordinate system and enable precise positioning and pathfinding.
are interested in heme biology. The explanations in the book are detailed
enough to capture the interest of the curious reader, and complete enough 136pp Mar 2020
to provide the necessary information for researchers to have an in-depth 978-981-121-691-6 US$28 £25
molecular understanding of heme biology and further their studies in this
fascinating realm.
280pp Feb 2020
facebook.com/worldscientific
978-981-121-128-7 US$108 £95For more information, visit: www.worldscientific.com WORLD SCIENTIFIC
EVOLUTION BIOLOGY CORRUPT CULTURES
“Fake News” and Cheating in Science
by Roy Y Calne (University of Cambridge, UK)
HUMAN CONSCIOUSNESS This book is concerned with cheating in Science
The Evolution of Our Sensor of Society and the harm that it does, concentrating on
by Irving C Statler (NASA Ames Research Centre, USA)
three disasters in cell culture, which caused
The book provides a consistent rationale for the evolutionary progression international concern and personal tragedy
from the simple, primitive, isolated organism to the complex, intelligent, for the perpetrators. There is an overview of
and social primates. A coherent explanation of why and how human plant, animal and human cheating, providing
consciousness evolved from elaboration of primary consciousness is a background to the focus on Science. This
given. The question, “What does human consciousness do and why does demands a special form of truth in that claims
it do it?” is answered. The book also offers a solution to the dilemma, “How need to be substantiated by repetition in independent laboratories to confirm
can anything material be conscious?” from my evolutionary approach to that the claims work. The nature of originality is examined in art and Science.
understanding human consciousness.
140pp Aug 2021
260pp Oct 2021 978-1-78634-560-8 US$48 £40
978-981-121-832-3 US$88 £75
THE MYSTERIOUS
DAWRIN: A COMPANION COMMONPLACE
With Iconographies by John van Wyhe
by Paul van Helvert (Wageningen A Life in Science
University & Research in Wageningen, by Charles DeLisi (Boston University, USA)
The Netherlands) & John van Wyhe “Charles DeLisi’s description of his life’s
(National University of Singapore) meanderings within science makes for
“This ‘Companion’ is magnificent, there is fascinating reading. Here is a true intellectual
no other word for it.” describing incidents within his life that
Gordon Chancellor many of us lesser mortals can immediately
Editor of Darwin’s Beagle appreciate. Life’s path is rarely smooth and
Notebooks from the Voyage of whether dealing with mundane teachers or
the Beagle individuals of the highest intellect one can both learn and be humbled
by the experience. ... I would recommend this to anyone looking for
This is the ultimate guide to the life and work of Charles Darwin. The result
of decades of research through a vast and daunting literature which is inspiration in their career choice and wondering when or if they should
hard for beginners and experts alike to navigate, it brings together widely change direction.”
scattered facts including very many unknown to even the most ardent Sir Richard J Roberts, PhD FRS
Darwin aficionados. It includes hundreds of new discoveries and corrections Nobel Laureate in Physiology or Medicine, 1993
to the existing literature. It provides the most complete summaries of his Chief Scientific Officer
publications, manuscripts, lifetime itinerary, finances, personal library, friends New England Biolabs
and colleagues, opponents, visitors to his home, anniversaries, hundreds Massachusetts, USA
of flora, fauna, monuments and places named after him and a host of other
180pp Aug 2021
topics. Also included are the most complete lists (iconographies) ever created
978-981-123-845-1 US$58 £50
of illustrations of the Beagle, over 1000 portraits of Darwin, his wife and
home as well as all known Darwin photographs, stamps and caricatures. 978-981-123-933-5(pbk) US$28 £25
The book is richly illustrated with 350 images, most previously unknown.
484pp Jan 2021 BRAIN FEVER
978-981-120-820-1 US$78 £70 How Vaccines Prevent Meningitis and
978-981-122-927-5(pbk) US$38 £35 Other Killer Diseases
by Richard Moxon (University of Oxford, UK)
GENERAL LIFE SCIENCES In Brain Fever, the internationally renowned
medical scientist, Richard Moxon FRS, shares 11
his experiences of bacterial meningitis, a fearful
CELLS AND STEM CELLS and devastating infection of the brain. In a clear,
The Myth of Life Sciences non-technical style, he explains what meningitis
by Dianliang Wang (China Association for is, what causes it, who gets it and how research
Science and Technology, China) & Haijia has come up with vaccines that can prevent it.
Chen (Guangzhou Saliai Stem Cell Science
In this must-read book, Brain Fever provides expert insight into what it takes
and Technology Co., Ltd., China)
to develop a vaccine. As we are learning from the COVID-19 pandemic, it
This popular science book systematically is vaccines that we rely on to fight and overcome the devastation caused
introduces major scientific and technological by virulent pathogens. His message is clear and challenging: no other
achievements in the field of cells and stem cells, intervention in the history of medicine confers a greater public health benefit
and the conveniences they bring to human life. than immunisation.
It covers plant cloning, animal cloning, human
264pp Jun 2021
cloning, biological missiles, biological drugs, immunocytotherapy, stem cell
978-1-78634-987-3 US$58 £50
therapy, stem cell bank, 4D printing, 5D printing, CAR-T technology, and
other frontier fields, which reflect the latest progresses and development 978-1-80061-001-9(pbk) US$28 £19.99
trends of life sciences. The book is both interesting and rich in information,
revealing the magic and mystery of life sciences.
230pp Oct 2021
978-981-123-877-2 US$58 £50
978-981-123-978-6(pbk) US$28 £25Life Sciences Catalogue 2022
MATHEMATICAL THE ABCS OF CANCER
MODELING OF VIRUS Separating the Facts from the Myths
by Meshach Asare-Werehene
INFECTION (The University of Ottawa, Canada)
ODE/PDE Analysis in R
by William E Schiesser (Lehigh University, This exciting reader-friendly book addresses the
USA) general perspectives of cancer in diverse ways
— everyday lifestyle, nutrition, environmental
Two models for the spread and control of
factors as well as genetics. The author, an
a virus are detailed in this book: The Lung/
expert in Immuno-Oncology, makes conscious
Respiratory System Model (LSM) and the SVIR
efforts to break down the complexities of cancer
(Susceptible-Vaccinated-Infected-Recovered)
development through the use of scientific
Model.
evidences and everyday activities. There are so many myths about cancer
Principal outputs from the ODE/PDE models are the levels of vaccinations out there. This book employs scientific basis to separate the facts from the
and infections. For the latter, the efficacy of the vaccine is a parameter that myths while making it comprehensible to all readers irrespective of their
can be varied in a computer-based analysis of a vaccine therapy. scientific background. Readers are also introduced to the modern trends
in cancer therapeutics.
The coding of the models is in R, a quality, open-source scientific computing
system, and can be executed on modest computers. The R routines are 200pp Jun 2020
available from a download link so that the example models can be executed 978-981-121-225-3 US$58 £50
without having to first study numerical methods and computer coding. The
routines can then be applied to variations and extensions of the ODE/PDE
models, such as changes in the parameters and the form of the model REVOLUTIONARY
equations. THERAPIES
How the California Stem Cell Program
180pp Mar 2021
Saved Lives, Eased Suffering — and
978-981-123-663-1 US$78 £70
Changed the Face of Medicine Forever
by Don C Reed (Americans for Cures
Foundation, USA)
WHAT MAKES YOU
UNIQUE? “Even for those of us who are familiar with
The Secrets of Genes and Heredity the science and progress of the clinical
by Lin He (Chinese Academy of Sciences, research, reading Don’s account provides
China), Bo Hai (Shanghai Media Group, such rich perspective and reminds us that all
China) & Chang Qin (Shanghai Media the datasets, graphs and lingo sometimes get in the way of conveying
Group, China) information in a way that addresses what matters most to the public
and patients ... With humility and respect, he discusses policy and
Why do twins look alike? How are we similar controversial issues such as the importance of fetal research and he
to our parents? What is the genetic code? does so in such a lucid and understandable way. The world has recently
Professor Lin He, an Academician of the changed because of stem cell research and Don’s book captures this
Chinese Academy of Sciences, shares his transformational time in history.”
childhood stories and knowledge of genetics in this vividly illustrated Maria T Millan,
popular science book. M D, President and CEO of CIRM
104pp Feb 2021 368pp Mar 2020
978-981-123-248-0 US$19.95 £20 978-981-121-328-1 US$98 £85
COMPUTATIONAL ALZHEIMER’S DISEASE
MODELING OF THE DECODED
COVID-19 DISEASE The History, Present, and Future of
Numerical ODE Analysis with R Alzheimer’s Disease and Dementia
12 Programming (2nd Edition)
by William E Schiesser (Lehigh University, by Ronald Sahyouni (University of
USA) California, San Diego, USA)
The book is intended for readers who are This book aims to present, educate and inform
interested in learning about the use of computer- individuals about Alzheimer’s disease in a
based modelling of the COVID-19 disease. It comprehensive manner. Its scope ranges from
provides a basic introduction to a five-ordinary the discovery of the disease, epidemiology and
differential equation (ODE) model by providing a complete statement of the basic biological principles underlying it, to advanced stem cell therapies
model, including a detailed discussion of the ODEs, initial conditions and used in the treatment of Alzheimer’s. It adopts a “global” perspective on
parameters, followed by a line-by-line explanation of a set of R routines (R is Alzheimer’s disease, and include epidemiological data and science from
a quality, scientific programming system readily available from the Internet). countries around the world.
The reader can access and execute these routines without having to first
280pp Oct 2021
study numerical algorithms and computer coding (programming) and can
978-981-123-510-8 US$58 £50
perform numerical experimentation with the model on modest computers.
108pp Jun 2020
978-981-122-287-0 US$48 £40
For more information,
visit: www.worldscientific.comFor more information, visit: www.worldscientific.com WORLD SCIENTIFIC
MEMORY MAKES THE ANDROCENTRISM
BRAIN The Ascendancy of Man
by Charles Pasternack (Oxford
The Biological Machinery that Uses
International Biomedical Centre, UK)
Experiences to Shape Individual Brains
by Christian Hansel (The University of Since time immemorial, men have assumed
Chicago, USA) superior innate qualities which have justified
The development of the young brain after birth them in exerting power over the other sex right
and the emergence of cognitive capacities, up to the twentieth century. The last few years
mind, and individuality rest on the maturation have seen the emergence of a new literary
of a dense net of synaptic connections between genre: to show that despite this, women have
neurons. Memory Makes the Brain describes managed to become outstanding writers, artists,
the dramatic, competitive elimination of surplus synapses that occur in scientists, explorers, rulers and politicians. Of such books, none discusses
the young, maturing brain — in a process called synaptic pruning that was a fundamental question: is the supposed male superiority biological, or has
discovered by pediatric neurologist Peter Huttenlocher in the 1970’s at it arisen for some other reason over the course of time?
the University of Chicago. Explaining similarities between developmental 200pp Oct 2021
pruning and learning processes in the adult brain, neurobiologist Christian 978-981-124-083-6 US$58 £50
Hansel offers a unique perspective on brain adaptation and plasticity 978-981-124-184-0(pbk)\ US$28 £25
throughout lifetime, at times weaving in personal accounts and memories.
192pp Jan 2021
978-981-122-880-3 US$78 £70 GENETICS AND GENOMICS
STRATEGIC LEARNING INTRODUCTION TO COMPUTATIONAL
A Holistic Approach to Studying METAGENOMICS
by Robert K Kamei (National University of by Zhong Wang (DOE Joint Genome Institute, USA &
Singapore, Singapore & Duke University, USA) Lawrence Berkeley National Lab, USA)
“Learning scientists have done a good job Breakthroughs in high-throughput genome sequencing and high-performance
of getting their findings to instructors to help computing technologies have enabled scientists to decode many genomes
them improve their teaching. But so much of including our own. Now there is a bigger ambition: to get a holistic view
learning is under the student’s — and only the of microbial communities within us and around us, gaining insights that
student’s — control. Strategic Learning fills a could revolutionize the view about our health and our environment. In
critical need to educate students on what the metagenomics, the DNAs of a microbial community are sequenced directly
field knows about how to learn productively. from the habitats without lab cultivation. This creates an enormous data
We should be getting it into the hands of every university student.” challenge, as metagenomics projects can generate tens of tera bases of
Lori Breslow sequences, equivalent to tens of thousands of human genomes.
Senior Lecturer, MIT Sloan School of Management This interdisciplinary book is essential reading for those who are interested
Founding Director, MIT Teaching & Learning Laboratory in beginning their own journey in metagenomics data science. It is a prism
to look through various intricate computational metagenomics problems and
200pp Jul 2021
understand their three distinctive aspects: metagenomics, data engineering,
978-981-122-663-2 US$58 £50
and algorithms. It is specially tailored for graduate students and advanced
978-981-122-777-6(pbk) US$28 £25
undergraduates from genomics science or computer science fields, but
beginner researchers from similar disciplines may also find it very useful.
STEM CELLS 300pp Apr 2022
From Hype to Hope 978-981-124-246-5 US$108 £95
edited by Khawaja Husnain Haider
(Sulaiman AlRajhi University, Saudi Arabia)
HOW TO CONSTRUCT
During the last two decades, stem cells have
progressed from merely a concept to a vibrant YOUR INTELLECTUAL 13
field of regenerative medicine which is aimed at PEDIGREE
addressing the root cause of the problem rather A History of Mentoring in Science
than conventional methods of intervention that by Elof Axel Carlson (Stony Brook
mostly provide symptomatic relief. University, New York, USA)
Given the significance of the field, the proposed book will be a compilation This is a handbook that shows the reader how
of the bench experience of experts from various research labs involved in to construct an intellectual pedigree. It is also
the cutting edge area of stem cell research. a history of science monograph because the
completed intellectual pedigrees can be used
280pp Mar 2020 individually or collectively to trace the influences of mentoring in the life
978-981-120-552-1 US$98 £85 sciences. The author uses Hermann Joseph Muller (1890–1967) (which
includes his own intellectual pedigree) to show how knowledge was shifted
from Italy to Germany and England, to France, and then to the American
Colonies. Through Muller, the author goes in two directions, one leading to
eTextbooks Available! Huxley, Darwin, and Newton. The second leads to Agassiz, Malpighi, Borelli,
and Galileo. The author also shows, from comparing 60 additional intellectual
Digital resources made convenient pedigrees, that about one third go to Newton, one third to Galileo and the
for your students at a lower cost. rest to other icons of the past.
348pp Aug 2020
978-981-121-582-7 US$98 £85You can also read
