INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc

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INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
INVESTOR
PRESENTATION
Year ended 31 December 2018

© CELLO HEALTH PLC
INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
2018 HIGHLIGHTS

    £104.8m of net revenue (2017: £102.5m)
    £12.2m headline profit before tax (2017: £11.4m)
    c. 970 professionals
    4% constant currency like-for-like net revenue growth and 12% operating profit growth in Cello
     Health division
    Headline earnings per share growth of 13.7%
    Net funds £6.3m; strong cash flows, and low earn out obligations
    Growing dividend, up 10.0%, 13th year of uninterrupted growth
    Big Pharma client base, with growing biotech and devices exposure under the Cello Health brand
    Growing healthcare client base under the Signal brand
    MSAs with 24 of the top 25* pharmaceutical companies - good visibility
    Change of name in the period to Cello Health plc
    New Non-Executive Directors reflect deeper health focus and experience of professional services

*pharmexec.com Top 50 Jun. 01 2018

© CELLO HEALTH PLC                                                                                     2
INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
OUR POSITIONING

                                           Scientific
                                           commercial services
                                                                 Marketing services
                     Clinical/commercial    MedEd/comms
                                                                  Digital/comms
                     services               Market access
                                                                  Advertising
                      CROs                 Regulatory
                                                                  Brand consulting
                      Clinical trials      Data/research
                                                                  PR
                      CMOs                 Consulting
                                            Pharmacovigilence

© CELLO HEALTH PLC                                                                    3
INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
CELLO HEALTH DIVISION: WHAT WE DO

SUPPORTING CLIENTS
                                                                                                                       Brand
ACROSS THE PRODUCT                      Pre-clinical       Pre-launch             Launch         Post-launch        optimisation
LIFECYCLE, WITH A
FOCUS ON EARLY
DRUG DEVELOPMENT

                            2018 NR: 30%                                   2018 NR: 29%                              2018 NR: 41%
    Analysis and Assessment                     Franchise and Brand Strategy                Landscaping and unmet needs
    Strategic Communication Planning            Scenario and Competitor Planning            Patient Journey
    Data Dissemination                          Launch Excellence                           TPP Optimisation
    Stakeholder Engagement                      Forecasting and Valuation                   Customer and Market Segmentation
    Education and Outreach                      Asset and Indication Prioritisation         Positioning and Message Development
    Patient Engagement                          Commercialisation Strategy                  Asset Tracking
                                                 Business Development
© CELLO HEALTH PLC                                                                                                                   4
INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
SOURCES OF COMPETITIVE ADVANTAGE

                     A fusion of advisory and delivery capabilities under one global lead brand
                     across pharmaceuticals, biotech, devices, OTC, social health and charities
                                  One brand, one team         Global presence
                                  • Cello Health brand        • Hub offices in New York,
                                  • BD culture                  Pennsylvania, London and Farnham
                                  • Marketing out-reach       • USA 45% of Cello Health division
                                  • Events                      2018 net revenues
                                  • Uniform bonus scheme      • 24 out of 25 top pharmaceutical
                                                                companies as clients

                                  Service innovation          Collaborative culture
                                  • Biotech                   • Cello Academy
                                  • E-Village                 • Centres of excellence
                                  • IQ                        • Graduate recruitment
                                  • Cello Health Logic        • Global business development team
                                  • Pulsar Health
                                  • Signal digital capacity

© CELLO HEALTH PLC                                                                                 5
INVESTOR PRESENTATION - Year ended 31 December 2018 - Cello Health plc
INVESTING IN TALENT

   Wide and deep talent pool
        c. 970 staff
        >60 PhDs
        59/41 female/male
        Average tenure of top 200 people = 10 years
   Strong incentive performance
     c. 19% of pre bonus headline operating profit paid as cash         Stable professional base
     Growing LTIP component
   Active hiring programme
     Graduate recruitment
     Dedicated human resource professionals
   Investment in training
        Cello Academy
        In the top 100 “Sunday Times Best Companies to Work For 2019”

© CELLO HEALTH PLC                                                                                  6
CELLO HEALTH: CLIENTS

 Top 20 clients = 40.1% of Group net revenue (2017: 38.9%)
 Largest client 7.9% (2017: 8.4%) of Group net revenue
        Long-term client spread over multiple therapy areas and buying
         points
 24 of the top 25 global pharmaceutical companies are clients
 15 out of the top 25 pharmaceutical companies have been clients         Good visibility
  for over five years
 Majority big pharmaceutical; growing biotech franchise
 US/Europe balance
 Balanced pre and post launch capability

© CELLO HEALTH PLC                                                                     7
MACRO GROWTH DRIVERS

                                                 Outsourcing trend

                                       Pricing
                                      pressure

                                 RX       CX trend

                              Growth of orphan drugs
                             and customised medicines

                           Regulatory and market access
                                     changes

                            Strong R & D and pipelines

                       Improved diagnostics and unmet needs

                                  Demographics

© CELLO HEALTH PLC                                                   8
CLIENT SPECIFIC TRENDS

 Orphan propositions increasingly making it direct to market
 Surge in interest in non-standard therapeutic solutions
        Immunotherapy
   Growing role of ‘real world data’ in verifying efficacy
   Patient engagement requirements increasing
   Pricing pressure raises need for efficiency in commercial delivery, speed to
    market and market impact
   New entrants disrupt established models
         Biosimilars

© CELLO HEALTH PLC                                                                 9
THE COMPETITIVE LANDSCAPE

   CROs migrating towards ‘soup to nuts’ solutions
     Inventiv + Research Inc = Syneos Health
     Quintiles + IMS = IQVIA
   Private Equity highly active                      Accelerating consolidation
        Parexel                                             of providers
   Range of emerging consolidators
     UDG
     Eversana
     Navigant

© CELLO HEALTH PLC                                                                 10
THE EMERGING CONSUMER AGENDA

                           CONSUMER

© CELLO HEALTH PLC                    11
CELLO SIGNAL

 Digital marketing and social media research solutions for big corporates
 Blue chip global client base: Healthcare, Technology, Financial Services, Public
  Sector, Utilities and Charities
 Solid core contracted revenue stream and visibility
 Consolidated office network: Edinburgh, London, Cheltenham, Los Angeles and
  Singapore
 Strong technology and proprietary software licensing model

© CELLO HEALTH PLC                                                                   12
DEVELOPING CELLO SIGNAL

                                                                        Specialist
                          Digital and Creative
                                                       Research       Communication
                           Communications
                                                                        Services
                                 LBG
                                                          TFL             Merlin
                                 RBS
                                                         Tesco            Marriott
                              A G Barr
                                                         Sony              IHG
                             Network Rail
                                                          Sky               HP
                                 RBL
                                                        L’Oreal         Hammerson
                                IFAW
                                                        Disney             P&O
                                WWF
                                                       Vodafone
                               Nando’s
                                                          EA
                     BUPA                     BRC       Netflix       Stryker (Medical
                     The Scottish              IMI        HP              Devices)
                     Government              IPHA                     The Food Doctor
                     EFPIA                  EUDF        Novartis
                     BHF                Macmillan     AstraZeneca
                     Novo Nordisk      Marie Curie       Sanofi
                                                     Wellcome Trust
© CELLO HEALTH PLC                                                                       13
FINANCIAL REVIEW

© CELLO HEALTH PLC                  14
FINANCIAL HIGHLIGHTS

                                                            2018       2017      %

                Reported basic earnings per share           6.27p      4.09p   ↑53.3%
                Headline basic earnings per share           9.02p      7.93p   ↑13.7%
                Net funds                                  £6.3m      £1.6m
                Full year dividend*                         3.85p      3.50p   ↑10.0%
                Net revenue                              £104.8m    £102.5m     ↑2.3%
                Like-for-like constant currency growth                          ↑1.4%
                Group headline profit before tax          £12.2m     £11.4m     ↑6.4%
                Reported profit before tax                 £8.4m      £5.8m    ↑44.7%
                Headline Group operating margin            12.0%      11.6%

*2018 final dividend subject to shareholder approval

© CELLO HEALTH PLC                                                                      15
SEGMENTAL ANALYSIS
                                       2018                                                  2017
                      Headline        Headline                             Headline         Headline
                                                        Margin                                              Margin
                     Net Revenue   Operating Profit                       Net Revenue    Operating Profit
                                                          %                                                  %
                          £m            £m                                     £m             £m

 Cello Health           64.3            11.9            18.5%                60.2             10.6          17.7%
 Cello Signal           40.0             3.7            9.4%                 41.0              3.9          9.5%
 Sub total             104.3            15.6            14.9%               101.2             14.5          14.3%
 Central cost             -             (3.1)             -                    -              (2.7)           -
 Group                 104.3            12.5            12.0%               101.2             11.8          11.6%

   6.1% increase in headline operating profit (7.8% constant currency)
   11.8% headline operating profit growth in Cello Health (13.8% constant currency)
   3.4% headline operating profit decline in Cello Signal (3.4% constant currency)
   Like-for-like net revenue growth in Cello Health of 2.8% (4.3% constant currency)
   Like-for-like net revenue decline in Cello Signal of 3.1% (2.9% constant currency)
   Currency headline operating profit translation headwind of £0.2m

© CELLO HEALTH PLC                                                                                                   16
CELLO HEALTH
                                           2018                 2017
                                                                                       Constant
                                           £’000                £’000    % Change
                                                                                    Exchange Rates

           Headline net revenue            64,308               60,150     6.9%          8.7%

           Headline operating profit       11,890               10,639    11.8%         13.8%

           Headline operating margins      18.5%                17.7%       -             -

    Constant currency operating profit growth of 13.8%
    Constant currency like-for-like net revenue growth of 4.3%
    Operating margin stronger at 18.5% (2017: 17.7%)
    Overall client base growing, especially in USA
    Collaborative wins grow strongly behind the Cello Health brand
    Both 2017 acquisitions performing as expected
    Opening of Philadelphia office in 2018
    Berlin and Boston opening in 2019

© CELLO HEALTH PLC                                                                                   17
CELLO SIGNAL

                                                  2018               2017
                                                                                                     Constant
                                                  £’000             £’000              % Change
                                                                                                  Exchange Rates

                     Headline net revenue         39,971             40,961             (2.4%)        (2.9%)

                     Headline operating profit    3,739              3,872              (3.4%)        (3.4%)

                     Headline operating margins   9.4%               9.5%                 -             -

       Constant currency operating profit decline of 3.4%
       Constant currency like-for-like net revenue decline of 2.9%
       Operating margin 9.4% (2017: 9.5%)
       Tougher trading conditions in the UK, although good performance in Edinburgh
       Full year impact of reduction in US capacity in 2017
       Rapid net revenue growth from Signal Health
       Significant health wins from Pulsar, shared with Cello Health

© CELLO HEALTH PLC                                                                                                 18
INCOME STATEMENT

                                                  2018    2017
                                                   £m      £m                    COMMENT

               Headline operating profit          12.5    11.8
               Interest                           (0.3)   (0.4)
               Headline profit before tax         12.2    11.4
               Restructuring costs                (0.2)   (1.9)   Much lower than 2017
               Credit for VAT received              -     0.3
               Start-up investment/biotech team   (1.2)   (1.4)   Pulsar US
               Acquisition costs                    -     (0.2)
               Amortisation of intangibles        (0.3)   (0.5)   Deal related
               Acquisition-related remuneration   (1.5)   (1.4)   Spread of deferred payments
               Share options                      (0.5)   (0.4)
               Reported profit before tax         8.4     5.8

© CELLO HEALTH PLC                                                                              19
CASH FLOW AND NET FUNDS

                                             2018    2017
                                              £m      £m                           COMMENT
 Net cash inflow from operating activities   13.4    4.8     Excellent operating profit conversion
 Interest                                    (0.3)   (0.4)   Non utilisation fee plus sundry interest - dropping
 Tax                                         (2.2)   (2.1)   Headline tax rate dropping from 2017
 Capex                                       (2.0)   (1.8)   Office moves/Pulsar
 Acquisitions                                (0.3)   (5.3)   Defined Health/Advantage in prior year
 Fund raise                                    -     14.2    Cash raise in prior year
 Share option proceeds                         -     0.2
 Dividends                                   (3.7)   (3.6)   Rising in 2019
 Foreign exchange movement                   (0.2)   0.7     Less exposure now US$ debt removed
 Net cash inflows                            4.7     6.7

 Opening net funds/(debt)                    1.6     (5.1)
 Closing net funds                           6.3     1.6     Facilities of £24m; expire in March 2022

© CELLO HEALTH PLC                                                                                                 20
OPERATING CASH CONVERSION

                                                  2018      2017    2016                   COMMENT
                                                   £m        £m      £m
  Headline operating profit                       12.5      11.8    10.5   Note growth record
  Depreciation                                    1.3       1.3     1.3
  Amortisation                                    0.4       0.4     0.4
  Headline EBITDA                                 14.2      13.5    12.2
  Cash flow from operations                       13.4      4.8     6.5
  Cash impact of non-headline items                   1.4   3.6     3.3    Start-ups/restructuring
  VAT settlement/receipts                              -    (0.3)   4.9    2016 VAT settlement
  Deferred remuneration                                -    2.3     0.2    iS Health settlement
  Headline operating cash flow                    14.8      10.4    14.9

                                                                           2017 shows reversal of underlying 2016
  % conversion of headline EBITDA                 104%      77%     123%
                                                                           surplus. 2018 strong performance
    Good underlying operating cash characteristics

© CELLO HEALTH PLC                                                                                                  21
BALANCE SHEET

                                                                                        2018                          2017
                                                                                         £m                            £m
 Goodwill                                                                               73.6                          73.0
 Intangible assets                                                                       1.4                           1.2
 Fixed assets                                                                            2.9                           2.8
 Deferred tax assets                                                                     1.5                           1.1
 Non-current assets                                                                     79.4                          78.1
 Current non cash assets                                                                47.9                          51.9
 Cash                                                                                   10.4                          13.0
 Creditors 1 year                                                                      (5.5)                         (12.8)
 Net assets                                                                             86.8                          82.9

    Total maximum deferred acquisition obligation of $6.3m payable over 3 years from 2019-2021, payable largely in cash

© CELLO HEALTH PLC                                                                                                             22
TAXATION AND DIVIDEND

TAXATION
 US tax charges implemented
 Lower than expected headline rate in 2018 of 21.6% as a result of US changes
 Expected headline rate in 2019 of 23.5%

DIVIDEND
 Full year dividend increased 10.0% to 3.85p* (2017: 3.50p)
 13 year unbroken dividend growth record

*2018 final dividend subject to shareholder approval

© CELLO HEALTH PLC                                                               23
SUMMARY AND OUTLOOK FOR 2019

   Strong growth in like-for-like fee income in Cello Health
   Increasing exposure to US market, organically and via potential acquisitions
   Leverage of Cello Signal digital capabilities into healthcare
   New office openings in Berlin and Boston in H1 2019
   Good operating cash generation
   Strong balance sheet
   Dividend continues to grow
   Strong start to the year
   Positive 2019 outlook based on current overall pipeline

© CELLO HEALTH PLC                                                                 24
APPENDIX

© CELLO HEALTH PLC              25
IFRS 9

IFRS 9 Financial Instruments

IFRS 9 replaces the provisions of IAS 39 that relate to; the recognition, classification and measurement of financial assets
and liabilities; depreciation of financial instruments; impairment of financial assets and hedge accounting.
The adoption of IFRS 9 resulted in changes to the accounting policy for trade receivables.
The requirement of IFRS 9 to use the expected loss method of impairment of financial assets did not have a material
effect on the Group due to the short-term nature of trade receivables, which are mainly due from large UK and US
clients.

© CELLO HEALTH PLC                                                                                                             26
IFRS 15

IFRS 15 Revenue from Contracts with Customers

IFRS 15 establishes a single comprehensive five-step model to be applied to all contracts with customers and replaces
the separate models for goods and services included in IAS 18 Revenue and related interpretations.
The core principle of IFRS 15 is that an entity should recognise revenue to depict the transfer of goods and services to
customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those
goods or services. Revenue is recognised when (or as) performance obligations in contracts are satisfied by transferring
control of the relevant goods or services to the customer.
The adoption of IFRS 15 did not have a significant impact on the Group’s operating profits or on the Group’s equity.
However, for certain contracts, the adoption of IFRS 15 resulted in a change in the timing of recognition of certain third-
party costs where the Group acts as principal with respect to services provided and associated revenue. As a result there
was a increase in third party costs of £1.0m in the year ended 31 December 2017 with a corresponding decrease in
revenue. There was therefore no impact on net revenue or operating profit.
The impact on the balance sheet at 31 December 2017 was to reduce current assets by £2.6m with a corresponding
decrease in current liabilities.

© CELLO HEALTH PLC                                                                                                            27
IFRS 16

IFRS 16 Leases - effective 1 January 2019

IFRS 16 introduces a comprehensive model for the identification of lease arrangements and accounting treatments for
both lessors and lessees. IFRS 16 will supersede the current lease guidance including IAS 17 Leases and related
interpretations. IFRS 16 removes the distinction between operating leases and finance leases and is replaced by a model
where a right-of-use asset and a corresponding liability have to be recognised for all leases by lessees except for short-
term leases or low value assets.
The Group has made an initial assessment of the impact of adopting IFRS 16.
The Group intends to apply the simplified transition approach and will not restate comparative figures for the year prior
to first adoption. Operating leases with less than 12 months remaining and low value leases will continue to be
recognised on a straight line basis as expensed to profit and loss.
For the remaining leases, principally in relation to land and buildings, the Group expects to recognise a right-of-use asset
of approximately £11.2m and lease liabilities of £11.1m, after adjustment for prepaid and accrued lease payments
recognised at 31 December 2018.
The Group expects operating profit to increase by approximately £0.1m and profit before tax to decrease by
approximately £0.1m as a result of adopting the new rules.

© CELLO HEALTH PLC                                                                                                             28
CONTACT US:

  MARK SCOTT, Chief Executive
  mark.scott@cellogroup.com
  +44 (0)20 7812 8462

   MARK BENTLEY, Group Finance Director
   mark.bentley@cellogroup.com
   +44 (0)20 7812 8463

                                          Thank You.

Cello Health plc
Queens House
8-9 Queen Street
London
EC4N 1SP

© CELLO HEALTH PLC                         www.cellohealthplc.com
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