IHP news 659 : A perfect storm - International Health Policies
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IHP news 659 : A perfect storm ( 4 March 2022) The weekly International Health Policies (IHP) newsletter is an initiative of the Health Policy unit at the Institute of Tropical Medicine in Antwerp, Belgium. Dear Colleagues, Unlike “Grand Convergence in Global Health” dreamers, I used to think the world was heading for a ‘Perfect Storm’ by 2030 or so. Turns out that was still overly optimistic. As if climate breakdown, massive global inequality and the pandemic weren’t bad enough, we now also entered a new geopolitical era - with a horrific bang. What’s going on in the Ukraine feels like a bizarre mix of the 19th, 20th and 21st century, with some of the ‘worst practices’ from earlier centuries (back) on our tv screens coupled with some not exactly enticing ‘innovations’ from this one (though I do like some of the global financial system wizardry). Anyway, it’s incredibly tragic and sad to watch. Perhaps even more tragic is that Nesrine Malik’s take in the Guardian - “Let the horror in Ukraine open our eyes to the suffering of war around the world” is – in the year 2022 – still so needed. Earlier this week, in an address to the Human Rights Council in Geneva, UN SG Guterres, while again referring to the “5-alarm global fire” threatening the international community, urged countries to mobilize to address the COVID-19 pandemic, global finance, climate action, lawlessness in cyber space, and peace and security. “The solutions to these crises are all rooted in human rights,” he told the Council. He’s absolutely right. Unfortunately, mankind currently faces a rather uphill battle to put out all these global fires in time, not unlike the (ill-fated) League of Nations in the 30s. As for human rights, I doubt they ever were much of a concern in the global corridors of power… Zooming in on just one of these ‘global alarms’, the climate emergency, the latest (ultra-bleak) IPCC report pointed out that the dangers of climate change are now mounting so rapidly that they could soon overwhelm our ability to adapt, with predicted impacts worst for ecosystems and humanity's most vulnerable. Or as Johan Rockström said, earlier this week, at a Club of Rome “anniversary webinar”, “Limits to Growth +50: Global equity for a healthy planet”: “for the first time IPCC talks about billions of people, not millions… “. One of the IPCC’s new messages is also that climate risks are ‘compounding’, i.e. climate change poses cascading risks to economies, social systems and business models. Along the same lines, the global chief of the Red Cross warned “ Governments must start treating the climate crisis as a national security concern on a par with war as climate breakdown threatens countries’ stability and safety”. Against this dark backdrop, the theme of this year’s World Health Day, “Our Planet, our Health ' might seem a bit naïve but is more urgent than ever. “In the midst of a pandemic, a polluted planet, increasing diseases …. on World Health Day 2022, WHO will focus global attention on urgent actions needed to keep humans and the planet healthy and foster a movement to create societies focused on well-being.” Add to that Owen Jones’ call for a global anti-war movement, in a nuclear era more needed than ever, and perhaps we can still leave this planet as a better place for our children and future generations. Indeed, now that all the intersections between crises are becoming increasingly clear for everybody (such as “fossil fuels funding war”, in the words of a fierce young climate activist 1
(Luisa Neubauer) at the abovementioned webinar from Wednesday), we better also heed her “take home message”: “… don’t be afraid in this era of shocks, this is in fact exactly the time to go out in the streets and ask for systems change to tackle all these massive but intersected crises.” Meanwhile, if you want it in the words of my generation ( and thinking of an old Sting song ), let’s hope Putin loves his daughters too. Though reading on his army’s shelling of a nuclear reactor this morning, you gotta wonder. Enjoy your reading. Kristof Decoster Featured Article ‘One Health’ should be the New Nexus of Global Health in the Middle East and North Africa Region Hoda K. Hassan (public health professional with an MPH from the School of Health and Related Research (ScHARR), The University of Sheffield, UK; pharmacist. On Twitter: @Hoda3011) COVID-19 was a watershed moment for all countries in the Middle East and North Africa (MENA) region, especially after decades of geopolitical and economic shocks. But even before the pandemic struck, sustainable development was already jeopardized by an unstable economic environment and scarce resources, among other challenges. See for example this 2014 Lancet report: “The dynamics of population change, ecological degradation, and resource scarcity, and development policies and practices, all occurring in complex and highly unstable geopolitical and economic environments, are fostering …. poor prospects [for health].” The MENA region is a global climate (crisis) hotspot and there’s also a constant threat of food and water insecurity. Over the past years, the region witnessed increased demographic pressure, rapid urbanization and increased cross boarder movement due to armed conflict and displacement. The MENA region is also a hotspot for zoonotic diseases, among others due to its geographic location under migratory birds' flight paths, mass gatherings (such as the Islamic pilgrimage, Hajj), political conflicts, and refugee crises. The region has a wide variety of wildlife interacting with the environment and allowing for zoonotic disease emergence and (re)-emergence. All this results in (potentially) devasting consequences: high morbidity and mortality, disruption of regional trade, extra stress on scarce public health resources. Unfortunately, in the region there is still a disconnect between population, environmental policies and health starkly putting its citizens at risk. Against this backdrop, rethinking health security in the region has become a matter of survival. In this piece we argue that a One Health approach should be a vital element of a global health approach “fit for the 21st century” in the region. As mentioned, the MENA region is characterized by a unique vulnerability to zoonotic threats. In recent years, infectious outbreaks were detected in a number of countries in the region, among others yellow fever, cholera, the spread of avian influenza A (H5N1) and the emergence of MERS- 2
CoV (2012). Antimicrobial resistance is also a serious threat in the region. An expert from the region put it in a Lancet World Report from 2019 like this: “….Middle Eastern conflict zones, such as Syria, Yemen, Iraq, and Gaza, face a “perfect storm” of circumstances to foster AMR, including destroyed or collapsed health-care systems amid ongoing conflict, unchecked and unregulated use of antibiotics, and lack of laboratories and other diagnostic tools.” In countries ravaged by conflict, the risk of developing a drug resistant infection due to treatment interruption is thus common and exposure to sewage and wastewater may lead to drug-resistant outbreaks, for example in refugee camps. Humanitarian crises can exacerbate infectious diseases. For example, Yemen was recently hit by one of the worst cholera epidemics in history. Amid the lack of basic amenities, chronic malnutrition, and unfavourable weather conditions, aerial transfer infection occurred by cholera-infected chironomid insects. Moreover, cultural habits, such as the consumption of unpasteurized dairy products, can trigger diseases that can spread between humans and animals. All these factors threaten regional health security. It’s quite a list, sadly. Against this backdrop, it is clearly time for the region to dedicate more attention to the animal kingdom and the environment, and how they directly affect health. The One Health approach connects disciplines across the human–animal–environment interface to address health through a coordinated, effective, efficient, and sustainable approach. Just a few months before the pandemic, a commentary titled “A chance to implement ‘One Health’ in the Middle East and North Africa” was published in The Lancet Planetary Health. It sparked a thought in my mind that ‘One Health’ could break the health security conundrum in the MENA region and strengthen health systems. It wouldn’t solve everything, but it’s a vital part of ‘Health for All’ in the region, I believe. While arguably, the introduction of a ‘One Health’ approach is not new in the region, practitioners have started to be more proactive lately in terms of adopting the approach. Egypt and Jordan are two countries that are paving the path towards (more) ‘One Health’ in the region. As the old saying goes, you must ‘make the most of what you have’, and so Egypt is now strengthening its existing ‘One Health’ capacities by capitalizing on a multisectoral coordination mechanism, the 4-Way Linking (4WL) Task Force which supports regular information sharing across four functional streams: epidemiology, laboratories, animal and human health. Recently, a ‘One Health Technical Advisory Group’ (OHTAG) has been established which presents a real opportunity to strengthen health systems resilience. This group calls on relevant sectors and disciplines to collaborate, communicate and coordinate key actions, and comes up with recommendations to address Priority Zoonotic Diseases (PZDs), including COVID-19 and antimicrobial resistance. In Jordan, Priority Zoonotic Diseases were identified using a ‘One Health’ approach and a systematized Center of Diseases Control (CDC) tool – One Health Zoonotic Disease Prioritization (OHZDP). Input from representatives of human, animal (livestock and wildlife), and environmental health sectors was collected during an OHZDP workshop. This was a great stride toward strengthening surveillance of emerging infectious diseases in the region. It is a steppingstone in the arena of strengthening health informatics and paves the way for countries in the region to leverage “Big data” to enhance the effectiveness of “One Health”. This is a wakeup call to integrate animal and environmental health into our response to future pandemics. As a chain is as strong as its weakest link, it is no longer plausible to work in silos. Consequently, ‘One Health’ should be the new nexus of global health in the region. MENA countries need to transition from traditional health strengthening approaches to approaches which also consider human societies and natural ecosystems. 3
On the bright side, the region supports the global calls for establishing a pandemic treaty. Indeed, it is crystal clear ‘One Health’ is not only a multidisciplinary collaboration but also a global health governance issue. As today’s crisis, the COVID-19 pandemic, should not go to waste, the International Centre for Comparative Environmental Law (CIDCE) recently developed a draft convention on pandemics. ‘One Health’ is still not integrated in international treaties, and so, determined to avoid the next pandemic, the draft convention calls for operationalizing ‘One Health’ through a pandemic treaty. In fact, the international NGO in special consultative status with the United Nations calls for the rapid conclusion of the pandemic treaty in the outcome documents of both UNEP@50 and Stockholm+50, in 2022 already, as this would help to promote progress in health law and environmental law globally, in harmony with nature, through a specific convention to combat pandemics. That might be a bit ambitious. But in a world with so many threats, it’s perhaps good to be ambitious. Highlights of the week UHC & PHC Cause we refuse to start with ‘Vlad’. WHO - Launch of the Primary health care monitoring framework and indicators https://www.who.int/news-room/events/detail/2022/02/28/default-calendar/launch-of-the- framework-and-indicators-for-monitoring-primary-health-care On Monday, “WHO and UNICEF jointly [released] a landmark Primary health care monitoring framework and indicators, the first-ever globally normative and endorsed primary health care measurement and monitoring framework, and the official measurement framework in support of the Declaration of Astana and Operational Framework for PHC. As countries strive to reorient their health systems around the principles of primary health care, this Framework responds to Member States’ request to monitor primary health care performance to accelerate progress towards universal health coverage and the other health-related Sustainable Development Goals.” For the new framework, see WHO: Primary health care measurement framework and indicators: monitoring health systems through a primary health care lens The new measurement framework supports all three components of PHC: 1) integrated health services w/emphasis on primary care & essential public health functions 2) multisectoral policy and action 3) empowered people and communities. WB “Investing in Health” blog - Don’t let the budget fool you https://blogs.worldbank.org/health/dont-let-budget-fool-you 4
“Despite being widely recognized as critical, evidence on how well the health budgets are being implemented in developing countries is not systematically collected. Further, the literature is scarce on how budget execution practices relate to health financing functions and service delivery. A new World Bank and WHO publication addresses this issue head on. The report identifies multiple ways in which budget execution practices can affect UHC goals…..” See the new WB/WHO report: Budget Execution in Health : Concepts, Trends and Policy Issues “…. there is no systematic evidence on how well the health budget is implemented and literature remains thin on how budget execution practices relate to health financing functions and service delivery. This report is the first in a series of publications on the topic following an active World Health Organization and World Bank collaboration. It aims to define concepts, characteristics and trends in health sector budget execution. The report first calls for clarity in use of terminology. It helps to differentiate between ‘budget execution rates’ and ‘budget execution practices’. The former refers to the share of the budget being executed. The latter to processes on how well the budget is executed. Both aspects are equally important. Not implementing the budget in full is a lost opportunity, efficiency and accountability concern and undermines the health sector’s ability to deliver services. It also undermines prospects for increased fiscal space going forward. To identify trends and patterns in over and underspending, the report draws on previously unexplored PEFA annex and World Bank BOOST data. This reveals the following: Health budget execution rates are inversely related to levels of income and maturity of PFM systems. Health budget under-execution is particularly pervasive in LMICs where the budget is executed at around 85-90 percent. Some countries have chronic budget execution problems where the budget is executed at a rate below 85 percent across consecutive years. In LMICs, the health budget is systematically implemented at a lower rate than the general government budget. This means, that governments are effectively deprioritizing health during budget implementation. For Sub-Saharan Africa countries in the sample, the average health budget was 6.7 percent of the general government budget. Health spending as a share of general government spending was half a percentage point less at 6.2 percent. In some countries this is much more pronounced, where health is deprioritized by 2-3 percentage points of general government spending during implementation. ….” International Women’s Day (8 March) Lancet World Report - International Women's Day: dismay at alcohol and arms ties https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00415-9/fulltext “Health advocates are concerned at the corporate capture of International Women's Day, with the alcohol industry and arms manufacturers backing a popular website. Sophie Cousins reports.” “Held on March 8, International Women's Day (IWD) is an annual event, recognised by the UN, that celebrates women while raising awareness of continued gender inequality, with events held around the world. The UN's theme for 2022 is “Gender equality today for a sustainable tomorrow”. However, women's health activists have expressed concern at how the day is being captured by corporate influences. The website internationalwomensday.com promises to celebrate women, provide guidance and resources to support IWD events, and provides a means to donate to female- focused charities. The website's hashtag, #BreakTheBias, has gained immense popularity on social 5
media channels and has been adopted by various organisations, companies, institutions, and celebrities. It is unclear who runs the website, and it does not appear to have any direct links to the UN. But the website lists several partners, including DHL, Nottingham Trent University, and several medical technology and pharmaceutical companies. The website is also supported by Northrop Grumman, one of the world's largest weapons manufacturers and military technology providers, and Lockheed Martin, a US aerospace, arms, defence, information security, and technology corporation with worldwide interests. It is also being supported by Diageo, one of the world's largest producers of alcohol, and Beam Suntory, another major alcohol producer….” Planetary health Guardian - IPCC issues ‘bleakest warning yet’ on impacts of climate breakdown https://www.theguardian.com/environment/2022/feb/28/ipcc-issues-bleakest-warning-yet- impacts-climate-breakdown “Report says human actions are causing dangerous disruption, and window to secure a liveable future is closing.” For the report, see IPCC: Climate Change 2022: Impacts, Adaptation and Vulnerability. “The Working Group II contribution to the IPCC Sixth Assessment Report assesses the impacts of climate change, looking at ecosystems, biodiversity, and human communities at global and regional levels. It also reviews vulnerabilities and the capacities and limits of the natural world and human societies to adapt to climate change.” Among others, “….The report says: Everywhere is affected, with no inhabited region escaping dire impacts from rising temperatures and increasingly extreme weather. About half the global population – between 3.3 billion and 3.6 billion people – live in areas “highly vulnerable” to climate change. Millions of people face food and water shortages owing to climate change, even at current levels of heating. Mass die-offs of species, from trees to corals, are already under way. 1.5C above pre-industrial levels constitutes a “critical level” beyond which the impacts of the climate crisis accelerate strongly and some become irreversible. Coastal areas around the globe, and small, low-lying islands, face inundation at temperature rises of more than 1.5C. Key ecosystems are losing their ability to absorb carbon dioxide, turning them from carbon sinks to carbon sources. Some countries have agreed to conserve 30% of the Earth’s land, but conserving half may be necessary to restore the ability of natural ecosystems to cope with the damage wreaked on them…..” PS: “…. … Monday’s IPCC publication is the second of four parts of the “sixth assessment report”, the latest in a series of comprehensive summaries of the world’s knowledge of the climate, stretching back to 1988. ….” • Related link: Science - U.N. panel warns of global warming's toll on humans and nature “Impacts will be worst for ecosystems and humanity's most vulnerable.” “….With temperatures already 1.2℃ warmer than in preindustrial times, some ecosystems are nearing a hard limit on their ability to adapt, including warm water coral reefs, coastal wetlands and rainforests, and the frigid mountain and polar realms, the report warns. And although humanity can 6
adapt to warming more easily than the natural world, it needs to move faster, says Michael Oppenheimer, a climate scientist at Princeton University and one of 270 report co-authors. “We’re not keeping up. The rate of climate change is faster than our ability to figure out how to deal with climate change.”” “….Most projects to adapt to this future are small, fragmented, and focused on near-term risks, the report finds. “There’s an adaptation gap,” Oppenheimer says. “Governments are paying much more lip service than actually doing a lot.” So far the adaptations mostly focus on water: levees and flood warning systems; coastal wetland restoration; soil moisture conservation for farming; and armoring of coastlines. Bolstering access to health care or establishing heat emergency plans would also make societies more resilient. And the report calls for adaptations to preserve the natural world: restoring the diversity of forests, aiding the migration of species, and protecting more lands and waters to give species space to adapt….” • And via Politico’s Global Pulse – New climate report suggests health systems are at risk “…. The newest report from the U.N.’s Intergovernmental Panel on Climate Change warns that health care is still at serious risk of being affected by climate change. The threats of increased disease, malnutrition, heat exposure, displacement and even mental health risks were mentioned in the new report, with negative impacts forecast across continents. The impact: The models of climate change impacts are often adding health care challenges to countries around the world — mosquitos will carry diseases like malaria farther in warmer conditions, for example. In turn, organizations that address these challenges are amending their plans; Malaria No More, among others, is working to develop improved capacity to meet the new needs. Aaron Bernstein, interim director of the Center for Climate, Health, and the Global Environment at Harvard’s school of public health, said two areas caught his eye in the new report: climate-resilient health systems and a more integrated approach to health care…..” “A rethinking: He told Global Pulse that climate financing should more often include the health sector, especially in low- and middle-income countries, to keep it up and running through climate shocks. That might require rethinking the mandate of climate-oriented organizations, he said. Bernstein also said that the health of humans, animals and ecosystems need to be seen as interconnected to tackle these problems in more effective ways….” Guardian - Climate emergency a ‘national security’ concern, says Red Cross https://www.theguardian.com/environment/2022/feb/27/climate-emergency-a-national-security- concern-says-red-cross “Governments must start treating the climate crisis as a national security concern on a par with war as climate breakdown threatens countries’ stability and safety, the global chief of the Red Cross has warned. Jagan Chapagain, secretary general of the International Federation of Red Cross and Red Crescent Societies, said: “People should be seeing the climate as a national security issue, as it is having an impact on national security. We need to see that the climate crisis is not only having an environmental impact, but a very significant security impact.”…” 7
Guardian - African countries spending billions to cope with climate crisis https://www.theguardian.com/environment/2022/feb/26/african-countries-spending-billions-to- cope-with-climate-crisis “Report says average 4% of GDP will be spent on adapting to climate breakdown, risking deeper poverty.” “African countries are being forced to spend billions of dollars a year coping with the effects of the climate crisis, which is diverting potential investment from schools and hospitals and threatens to drive countries into ever deeper poverty. Dealing with extreme weather is costing close to 6% of GDP in Ethiopia alone, equating to a spend of more than $1 repairing climate damage for every $20 of national income, according to research by the thinktank Power Shift Africa….” Guardian - World leaders agree to draw up ‘historic’ treaty on plastic waste https://www.theguardian.com/environment/2022/mar/02/world-leaders-agree-draw-up-historic- treaty-plastic-waste “UN environment assembly resolution is being hailed as biggest climate deal since 2015 Paris accord.” “World leaders, environment ministers and other representatives from 173 countries have agreed to develop a legally binding treaty on plastics, in what many described a truly historic moment. The resolution, agreed at the UN environment assembly in Nairobi, Kenya, calls for a treaty covering the “full lifecycle” of plastics from production to disposal, to be negotiated over the next two years. It has been described by the head of the UN Environment Programme (UNEP) as the most important multilateral environmental deal since the Paris climate accord in 2015….” 50 million Euros to seed new Nature for Health Trust Fund for Pandemic Prevention https://www.unep.org/news-and-stories/press-release/50-million-euros-seed-new-nature-health- trust-fund-pandemic “The German Federal Ministry for the Environment, Nature Conservation, Nuclear Safety and Consumer Protection (BMUV), the UN Environment Programme (UNEP), and the Secretariat of the Convention on Biological Diversity (SCBD) today jointly announced the establishment of a Multi- Partner Trust Fund (MPTF) on Nature for Health. Announced on World Wildlife Day, the Fund – through an initial contribution of 50 million Euros from Germany’s International Climate Initiative (IKI), brings together leading UN agencies, intergovernmental organizations and civil society groups in the field of environment and health… …. The new Fund will help countries achieve more holistic policymaking by creating further evidence of the links between biodiversity, climate and health, and will support decision makers and relevant actors to take measures to prevent future pandemics. Through application of enhanced One Health approaches, the Fund aims to achieve improved policies and cross-sector collaboration. “Above all, the Multi-Partner Trust Fund will focus on implementation…..” 8
FP2P blog - What has global military spending and emissions got to do with development? Rather a lot. D Burton; https://oxfamapps.org/fp2p/what-has-global-military-spending-and-emissions-got-to-do- with-development-rather-a-lot/ “Global military spending is currently $2 trillion per year, twice as much as at the height of the Cold War. Although the emissions data available is far from comprehensive, it’s obvious that military spending literally fuels military GHG emissions…..” Nature (Comment) - G20’s US$14-trillion economic stimulus reneges on emissions pledges J Nahm et al; https://www.nature.com/articles/d41586-022-00540-6 “Analysis of pandemic economic recovery packages from the 20 largest economies reveals that governments are not spending on emissions cuts despite promises to ‘build back better’.” Covax & ACT-A Reuters - Factbox: Vaccines delivered under COVAX sharing scheme for poorer countries Factbox: Vaccines delivered under COVAX sharing scheme for poorer countries | Reuters As of earlier this week, the COVAX facility had delivered 1.33 billion Covid-19 vaccine doses to 144 countries, so far. COVAX — A broken promise for vaccine equity Jessica Malter & and Kate Elder (MSF Access Campaign) https://msf-access.medium.com/covax-a- broken-promise-for-vaccine-equity-fb8b398b56f0 Blog on why COVAX has not been the great equaliser we were promised, and what needs to happen to improve vaccine equity around the world. 9th ACT-Accelerator Facilitation Council meeting (29 Feb) https://www.who.int/news-room/events/detail/2022/02/28/default-calendar/9th-act-accelerator- facilitation-council-meeting Check out the presentations, with among others: Update on ACT-A advocacy campaign Chair: (John- Arne Røttingen, Ambassador for Global Health, Norway); Where are we in relation to global targets (Scott Pendergast, Health Systems & Response Connector); and two country spotlights (Rwanda & Kenya). 9
UN News - COVID-19: Germany first to contribute ‘fair share’ for vaccine equity push https://news.un.org/en/story/2022/03/1113072 “Germany has become the first country to answer a call for wealthy nations to contribute their “fair share” towards ending the COVID-19 pandemic, the World Health Organization (WHO) reported on Tuesday. The country has committed to provide $1.22 billion to support the ACT- Accelerator, the global partnership for equitable access to tests, treatments, vaccines, and personal protective equipment (PPE). The mechanism requires $16.8 billion to meet urgent needs. … …. German Finance Minister Christian Lindner, announced the pledge at the G7 Finance Ministers’ Meeting, which was held virtually. ….” TRIPS waiver discussions / tech transfer… Some news & analysis from this week: TWN - Russia-Ukraine conflict casts a pall at WTO, raising doubts over MC12 R Kanth; https://wp.twnnews.net/sendpress/email/?sid=NjQ4ODA&eid=NDUyOQ “The sudden flare-up of Russia’s military conflict with Ukraine seems to have cast a pall over the World Trade Organization on 24 February, raising doubts as to whether the WTO’s 12th ministerial conference (MC12) could be held if current developments continue to worsen in the coming days, said people who asked not to be quoted. Even though there are more than three months to go before MC12 reconvenes in the week of 13 June, the continued precipitation of the tensions, including the magnitude of economic and other sanctions being imposed on Russia, could throw “a spanner in the works” in the run-up to the ministerial conference, said several members, who asked not to be quoted…..” HPW - WHO Director General Calls On WTO To Take ‘Practical’ Action On IP Waiver For COVID Vaccines & Medicines https://healthpolicy-watch.news/who-welcomes-un-security-council-resolution/ From late last week. “WHO Director General Dr Tedros Adhanom Gheyebresus on Friday issued his strongest call to date for a waiver on intellectual property related to COVID vaccines, medicines and other health products – which is due to be considered next week by the World Trade Organization’s General Council….” “While welcoming a new UN Security Council resolution also approved on Friday, which calls for broader access to COVID vaccines in conflict zones and poor countries, Dr Tedros stressed that the UN resolution needed to be accompanied by concrete global actions of the kind that the WTO was positioned to take – by relaxing rules that restrict the generic manufacture and trade in patented COVID vaccines and health products. …. ….. …. The UN Security Council resolution, which was 10
passed unanimously, calls for “the strengthening of national and multilateral approaches and international cooperation.. to facilitate equitable and affordable access to Covid-19 vaccines in armed conflict situations, post-conflict situations and complex humanitarian emergencies.” It also calls on developed economies to donate vaccines to low- and middle-income countries and other countries in need…..” Politico - WTO Director-General Ngozi Okonjo-Iweala calls for more 'political will' on Covid, future pandemics https://www.politico.com/news/2022/02/25/wheres-the-political-will-wto-director-calls-for-more- collaboration-for-covid-future-pandemics-00011860 From last weekend. “Ngozi Okonjo-Iweala, the director-general of the World Trade Organization, told POLITICO that member states are still in “difficult” conversations about a potential agreement on an intellectual property waiver that would allow countries to more easily manufacture the Covid-19 vaccine.” Some excerpts: “For more than a year, WTO members have discussed a possible agreement on a Trade-Related Aspects of Intellectual Property Rights waiver. In recent weeks, Okonjo-Iweala and a small group of representatives, including those from the U.S., European Union, South Africa and India, have held targeted talks about a potential agreement. Okonjo-Iweala met with the organization’s general council this week in Geneva to discuss what she described in an interview as a “landing zone.” Striking a deal on the waiver will not be easy, said Okonjo-Iweala, who added that smaller, closed- door conversations would continue ahead of the WTO ministerial meeting the week of June 13….” “…Over five years, the world should spend $75 billion, $15 billion a year of which $10 billion goes into a financial intermediary fund that could be managed by the World Bank to prepare for the next pandemic. And the point is that there’s reluctance to come up with this money. We’ve spent $26 trillion in fighting the pandemic. But we are not ready to spend $75 billion for starting prevention now. That is wrong. That is plain, absolutely wrong…. “…Is an agreement for an IP waiver on diagnostic materials and therapeutics achievable? A: It would be jumping too fast. People need to wait and see what we come up with respect to vaccines before we move on to therapeutics…..” Geneva Health Files - Efforts to Narrow the TRIPS Waiver Continue: "Eligibility Requirements" Still on The Table Geneva Health Files Must-read analysis from last week on Friday. “…a comprehensive analyses on the state of play in the TRIPS Waiver discussions and the factors outside of it, that are shaping these negotiations. Surely and slowly they are now entering a crucial phase. ….” “….The TRIPS waiver discussions at the WTO continue to teeter on the brink of a possible outcome that risks becoming too complicated to use. More importantly, the discussions continue to be mired in narrow eligibility requirements that could potentially set conditions on the circumstances under which a waiver will be applicable. This essentially aims to achieve the lowest possible 11
“impact” of a potential waiver, sources suggest. As we reported earlier, it is understood that these proposals continue to be pushed by the US and the EU…..” “….Eligibility requirements are understood as conditions under which a potential waiver will be applicable. It is learned that language could be crafted in a way that will effectively exclude countries such as India and China, without explicitly stating so. …. ….Africa continues to be a priority for the EU, and some suggest that the efforts to limit implementation of a waiver to the continent may be a part of this broader diplomatic goal. …. ….Apart from restricting the implementation of a potential waiver to specific geographies, the EU and the US have suggested other limitations. ….….While the EU is unwilling to relent on IP scope, the US continues its stance on restricting the waiver to vaccines, effectively reducing the product scope of the waiver…..” “…As mentioned earlier, Africa has become a key strategic priority for the EU during the pandemic. The emphasis on EU’s support to the South Africa mRNA hub is a case in point. ….while investing in mRNA hubs in Africa might be a useful diplomatic goal for the EU, it is also an effective policy to deflect potential commitments in the TRIPS Waiver discussions that seek to decentralize and boost manufacturing capacities everywhere and not just in Africa….” “Assuming that a narrow waiver proposal does get approved at the WTO, what will be the implications? Supporters of the waiver believe that it could still be helpful to developing countries. They also suggest that when COVID-19 does become endemic, there will continue to be a need for a waiver in order to access medical products easily…..” Developers of a key mRNA delivery tech, seeking a piece of Moderna's Covid riches, sue for patent infringement https://endpts.com/developers-of-a-key-mrna-delivery-tech-seeking-a-piece-of-modernas-covid- riches-sue-for-patent-infringement/ “The lawsuit that Moderna has been dreading finally got to it. Arbutus and Genevant have sued the big biotech for infringing on their patent on a lipid nanoparticle platform that they say was crucial to the delivery of Moderna’s widely-used Covid-19 vaccine…..” See also the Washington Post - Moderna faces new lawsuit over lucrative coronavirus vaccine “The suit is the second patent fight over the development of the messenger RNA shot.” “Moderna faces yet another patent challenge over its coronavirus vaccine after Arbutus Biopharma and Genevant Sciences, both small biotechnology companies, filed a lawsuit on Monday alleging Moderna hijacked its technology to develop the multibillion-dollar vaccine. Arbutus and Genevant said in their lawsuit that Moderna infringed on their patent for so-called lipid nanoparticle technology, which they say was key in the development of Moderna’s mRNA vaccine and took scientists from Arbutus and Genevant “years of painstaking work to develop and refine.” The Conversation - A South African company addresses vaccine supply inequity, despite Canada’s lack of support M Herder et al ; https://theconversation.com/a-south-african-company-addresses-vaccine-supply- inequity-despite-canadas-lack-of-support-177416 12
“…. Afrigen Biologics, a South African based company, produced its own version of Moderna’s mRNA COVID-19 vaccine. This was achieved with no support from Moderna or Pfizer-BioNTech, the manufacturer of the other mRNA vaccine. What many don’t realize is that two Canadian companies control a key component of the mRNA vaccines. Busy fighting over their lucrative patent rights, there is no sign they shared their technology with Afrigen either. The two companies in question — Acuitas Therapeutics and Arbutus Biopharma — are based in Vancouver, B.C., and have strong ties to the University of British Columbia. They have been lauded for their positive “global impact” in combating the pandemic. But that impact seems to stop short of sharing their technology with Afrigen and other would-be suppliers of COVID-19 vaccines in the Global South…..” And a link: South Centre - Direct Monetary Costs of Intellectual Property for Developing Countries: a changing balance for TRIPS ? C-TAP WP - U.S. to share some coronavirus technologies with World Health Organization U.S. to share some coronavirus technologies with World Health Organization - The Washington Post “Plan would allow other countries to replicate American scientific breakthroughs, intended to boost supplies to fight pandemic.” “The Biden administration will share U.S. government-devised coronavirus technologies with the World Health Organization, a policy shift intended to allow other countries to replicate some American scientific breakthroughs and better fight the pandemic abroad, according to three people with knowledge of the announcement who were not authorized to discuss it. Under the plan, some technologies now being developed by the National Institutes of Health will be licensed to WHO’s COVID-19 Technology Access Pool, the people said. The technologies will also be sub-licensed to the United Nations-backed Medicines Patent Pool…..” “….The policy is not intended to apply to the vaccines and therapeutics that have been developed by private companies and are currently in the U.S. market, the people said. The United States is not expected to share NIH-developed technology that was used by Moderna….” “….Sharing the technologies behind NIH-devised coronavirus diagnostics, treatments and vaccines is intended to allow other nations and developers to replicate the manufacturing process. As a result, officials expect the decision to more quickly build a global stockpile of supplies to combat the pandemic….. U.S. participation in the WHO pool could jump-start global donations of such technologies, officials and advocates said…..” Link: WHO - WHO and MPP welcome NIH’s offer of COVID-19 health technologies 13
Other news/analysis/reports on Global Health Governance, financing & security Geneva Health Files - Game on at WHO: International Health Regulations Vs The Pandemic Treaty GHF “…. the first edition of Treaty Talks, a new series that will track negotiations around a potential pandemic treaty in the coming months (and years). This edition is a comprehensive analysis of the first meeting of the Intergovernmental Negotiating Body that took place last week (Feb 24)…..” In-depth analysis. Starting with: “….The bombing of Ukraine by Russia has likely changed the delicate discussions on a pandemic treaty. After all, Russia was one of the key voices countering the proponents of the treaty, raking up the centrality of International Health Regulations and arguing against the rush for a treaty…..” PS: Priti Patnaik concludes: “….In the coming months, a slew of simultaneous proposals will progress on parallel tracks to collectively transform the ways to govern health emergencies. At the world health assembly in May, the following proposals will be considered: a formal decision on the US proposal to amend the IHRs may be considered; the Austrian proposal for a Standing Committee on Health Emergency; a UK sponsored resolution on clinical trials; an action plan formulated by the WGPR; recommendations by the Sustainable Financing Working Group. In addition, the DG will also present a set of proposals for strengthening the global health architecture for emergency preparedness, response and resilience…..” HPW - 13 African Nations Have Expressed Interest in Hosting the New African Medicines Agency https://healthpolicy-watch.news/13-african-nations-bids-new-ama/ “Some thirteen African nations have expressed interest in hosting the new African Medicines Agency, with an AU decision on where to establish the AMA’s headquarters set for July 2022, senior African Union officials say. A decision on a headquarters would also pave the way for the recruitment of a director general for the new AMA agency. And if the DG selection is completed by the third or fourth quarter of 2022, as expected: “from there the AMA will be ready for takeoff.”….” Development Today - Unsolved dispute over counting COVID vaccine donations as aid leaves loopholes Development Today; “After seven months of wrangling about how to report COVID-19 vaccines donated to developing countries as aid, the OECD issued last-minute guidance for donors. One expert says it could lead to a “free for all” and civil society actors warn of a “massive diversion” of aid. …. OECD Development Assistance Committee recommends donors report $6.72 per donated dose. If they use this rate for all vaccine donations, it could inflate global aid by >USD 6 billion in 2021…..” 14
Report - Global Public Investment for Pandemic Preparedness and Response https://secureservercdn.net/160.153.137.14/qjz.3c1.myftpupload.com/wp- content/uploads/2022/02/GPI-for-Pandemic-Preparedness-and-Response.pdf?time=1645692427 “The report offers details on how a functioning system of Global Public Investment (GPI) could actually operate for a particular sector of global cooperation - all contribute, all decide, all benefit. With snowballing agreement on the principles underpinning GPI, the challenge is now putting it into practice. … The paper demonstrates how GPI would meet substantial PPR financing needs in five basic ways: 1. fair share financing for ongoing investments; 2. inclusive governance and decision- making; 3. public investments for equity; 4. reduced volatility through statutory financing; 5. countering nationalism with incentives for a common framework.” The report is also available on the GPI website: https://globalpublicinvestment.org/resources/ FT - Billions required to prevent next pandemic, warns epidemic expert https://www.ft.com/content/dc0d8407-446d-4fb5-86a5-a628bed4d786 “Governments must invest billions of dollars to prevent the next pandemic and begin constructing a library of vaccines for every single family of viruses, says the organisation charged with preparing the world for emerging infectious diseases. Richard Hatchett, chief executive of the Coalition for Epidemic Preparedness Innovations, said it could take as little as five years to create the vaccine bank that could be adapted when a threat was detected, to ensure the world could start vaccinating within 100 days. Vaccine makers were able to deliver Covid-19 vaccines in record time partly because they were already developing jabs for Mers, another coronavirus. But Hatchett said that unless shots were prepared for other virus families, the world might not be as lucky next time…..” “….Cepi has so far raised $300mn from Japan and about $213mn from the UK, as well as funds from Germany and Norway. The Wellcome Trust and Gates Foundation kicked off its campaign with $300mn. But it is still far short of its goal to raise $3.5bn. The donations also tend to come from budgets earmarked for health or international aid rather than those aimed at security threats….” NEJM (Perspective) - Delivering Pandemic Vaccines in 100 Days — What Will It Take? M Saville, R Hatchett et al ; https://www.nejm.org/doi/full/10.1056/NEJMp2202669?query=featured_home « ….. We interviewed 46 representatives from vaccine-development firms, international organizations, regulatory agencies, academia, and the media to identify innovations that could shorten the development process and challenges that would need to be overcome to meet the 100- day goal, focusing on the first SARS-CoV-2 vaccines to be approved by a stringent regulatory authority (the Pfizer–BioNTech, Moderna, and AstraZeneca products). We reviewed reported development timelines and lessons learned to come to a consensus about the most condensed timeline under which vaccines could be developed if these lessons were applied…..” 15
Conclusion: « …. Stopping the next pandemic, let alone in 100 days, isn’t something that a single country or organization can do alone. Success will require advances in the organization, governance, and financing of global-preparedness systems and the development of multiple interconnected, scientifically guided collaborative efforts. We believe the “moonshot” goal of making a vaccine against a new pandemic pathogen available in 100 days is ambitious but is within reach. » Science - Spurred by pandemic, U.S. government will revisit federal policies on risky virus research https://www.science.org/content/article/spurred-pandemic-u-s-government-will-revisit-federal- policies-risky-virus-research “Advisory panel asked to examine whether definition of certain gain-of-function studies should be expanded.” “In the wake of the coronavirus pandemic, the U.S. government is revisiting its oversight of experiments that involve modifying pathogens in ways that might make them more harmful to people. Yesterday, White House officials and the National Institutes of Health (NIH) asked an expert advisory board to undertake a swift, broad review of the agency’s policies that aim to make sure federally funded studies of viruses and other microbes that could cause a pandemic are undertaken safely, and to bar funding for experiments deemed too risky. The review—to be conducted over 10 months by the National Science Advisory Board for Biosecurity (NSABB)—could include consideration of whether controversial coronavirus experiments funded by the United States in China should have received stricter scrutiny. The panel might also explore whether the United States should fund any such pathogen research conducted abroad, where NIH may have less ability to enforce its rules…..” South Centre - Can Negotiations at the World Health Organization Lead to a Just Framework for the Prevention, Preparedness and Response to Pandemics as Global Public Goods? V M Tellez; https://www.southcentre.int/research-paper-147-28-february-2022/ “This paper advances that WHO Member States, having agreed to the objectives of advancing equity and solidarity for future pandemic prevention, preparedness and response, now must operationalize these. The paper offers suggestions for the ongoing WHO processes of: 1) review of recommendations under examination by the Working Group on Strengthening WHO Preparedness and Response to Health Emergencies, 2) consideration of potential amendments to the International Health Regulations (IHR) 2005, and 3) elaboration of a draft text for an international instrument on pandemic preparedness and response.” TWN - WHO: Africa Region calls for amendment of IHR to address equity https://www.twn.my/title2/health.info/2022/hi220301.htm “Member States from the WHO Africa Region called for the inclusion of equity provisions within the potential amendments to the International Health Regulations (IHR) 2005 during the 7th meeting of the Member States Working Group on Strengthening WHO Preparedness and Response to 16
Health Emergencies (WGPR). The 7th Meeting of the WGPR took place on 21-23 February at the WHO Geneva Headquarters in a hybrid mode….” “…. The Africa Group recommended “that Equity should be addressed both within the potential IHR (2005) amendments as well as the new international instrument…. “…. the Africa Region submitted an indicative list of proposals on improving equity under IHR as follows:….” CGD Notes - The IMF and Health Taxes: Progress Falters during COVID-19 Emergency C Lane; https://www.cgdev.org/publication/imf-and-health-taxes-progress-falters-during-covid-19- emergency “Corrective taxes on harmful products—health taxes—are a cost-effective way to save lives and generate additional tax revenue. Our previous work shows that corrective tax revenue from alcohol, tobacco, and sugar-sweetened beverages remains well below the health-related costs from consumption (externalities and internalities). We survey measures taken in IMF lending to 93 countries during 2017–2021. We show that health tax measures during COVID-19 have diminished in number and strength because the international community has mobilized additional, largely unconditional financing to fill budgetary gaps and because countries sought to cushion consumers’ reduced spending power by delaying new or increased taxes. But, as policymakers look to medium- term budget consolidation, international financial organizations (IFIs), especially the IMF, have an important role to play in ensuring health taxes move forward more rapidly. We reiterate an action agenda on health taxes for the IMF in coordination with other international agencies….” Guardian - Melinda French Gates says she is ‘friendly’ but not friends with Bill Gates https://www.theguardian.com/us-news/2022/mar/03/melinda-french-gates-friendly-bill-gates “Melinda French Gates has addressed her divorce from Bill Gates publicly, saying that although she and the Microsoft co-founder are “friendly at this point”, she is not ready to label her relationship with Gates as “friends”. In a recent interview with CBS’s Gayle King, French Gates said multiple factors resulted in the couple’s high-profile divorce last May after 27 years of marriage….” Ukraine HPW - WHO Appeals for Humanitarian Corridor in Ukraine to Enable Delivery of Medical Supplies https://healthpolicy-watch.news/who-ukraine/ 17
“The World Health Organization (WHO) has appealed for a “humanitarian corridor” to enable it to deliver emergency medical supplies to sick and injured Ukrainians – particularly oxygen, insulin and supplies to treat battle wounds…..” And a link: CNBC - ‘We are not politicians’: WHO avoids naming Russia as it condemns attacks on civilians and hospitals in Ukraine Reuters – WHO sees little impact on COVID-19 vaccine supplies to Africa over war in Ukraine https://www.reuters.com/world/africa/who-sees-little-impact-covid-19-vaccine-supplies-africa- over-war-ukraine-2022-03-03/ “The World Health Organization said on Thursday it does not expect immediate impact on vaccine supply to Africa due to the fighting in Ukraine, and that Russia's Sputnik COVID-19 vaccines were a minimal component of imports to the continent.” Links: • Lancet Offline – Offline: Ukraine and the lessons of Alexander Herzen (R Horton) “….What connects this European war to a global pandemic? One word: security. This concept is not fashionable in global health. We prefer to talk about sustainability. Securitisation is seen as anathema to the values of global health—the progressive expansion of rights, equity, and social justice. Serious efforts have been made to redefine the notion of security to accommodate these concerns. The most definitive statement came from the 2003 Commission on Human Security, Human Security Now. … ….. As western nations debate how to address the ongoing conflict in Ukraine, human security must be put on the security agenda—by the UN Security Council and WHO. So far, these multilateral actors have been weak in both words and deeds. ….” • Devex - China-based AIIB and NDB halt work in Russia as sanctions hit COVID-19 Global Research and Innovation Forum HPW - Expanding Global Research Capabilities to Prepare for Future Pandemics https://healthpolicy-watch.news/global-research-future-pandemics/ Coverage of the Covid-19 Global Research and Innovation forum from last week. “From increasing disease surveillance and developing a pan-coronavirus vaccine to ‘eco-health’ and public trust, participants in the COVID-19 Global Research and Innovation Forum considered ways to globally prepare for future pandemics and end the current one. The third such forum, hosted by the World Health Organization, brought together over 100 research scientists, experts, policy 18
makers, and donors worldwide to discuss and strategize about the future of COVID-19 research 24- 25 February. ….” Covid key news PS: The (official) death toll from COVID-19 is expected to reach 6 million this week. The real toll is probably around 20 million by now. Not to mention all the long Covid sufferers. AP - COVID cases, deaths continue to fall globally, WHO reports https://apnews.com/article/coronavirus-pandemic-business-health-pandemics-united-nations- 269660a4236ad73527d057fd6b74d816 “The number of new coronavirus cases reported globally dropped by 16% last week, marking a month-long decline in COVID-19 infections, according to figures from the World Health Organization. In its weekly report on the pandemic issued late Tuesday, the U.N. health agency also said that deaths fell by 10%, continuing a drop in fatalities first seen last week. WHO said there were more than 10 million new cases and about 60,000 deaths globally. The Western Pacific was the only region where COVID-19 increased, with about a third more infections than the previous week. Deaths rose by 22% in the Western Pacific and about 4% in the Middle East, while declining everywhere else. WHO said the omicron variant remains overwhelmingly dominant worldwide; among virus sequences shared with the world’s largest publicly accessible database, more than 99.5% were omicron while only 0.3% were delta. In the last month, none of the other worrying variants — including beta, gamma, lambda or mu — have been reported, although WHO said there were surveillance challenges in many countries…..” See also Cidrap News - Global COVID cases, deaths drop, except in key hot spots Reuters - Analysis: Is WHO's aim to vaccinate 70% of world by June still realistic? Reuters; “Vaccinating 70% of the population in every country in the world against COVID-19 by mid-2022 has been the World Health Organization's (WHO) rallying cry to end the pandemic. But recently, public health experts say that while boosting immunity globally remains essential, the figure is neither achievable nor meaningful.” Some excerpts: “…. WHO head of immunization Kate O'Brien said 70% remained more than just a "rallying cry", even though some well-equipped countries with plenty of vaccines have also struggled to reach it. "We are calling for countries to be serious about their actions towards achieving that target, while acknowledging that - on a country-by-country basis - there may be a rationale why that target is not specifically suited to that country," she told Reuters…. “…. Gavi, the Vaccine Alliance - WHO's partner in the COVAX initiative aimed at getting shots to the world's poorest – has pulled back from the "one-size-fits-all" 70% focus. At a virtual briefing last week with WHO Africa, Aurelia Nguyen, managing director of COVAX within Gavi, said it was 19
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