Effectiveness of Diabetes Self - Management Education in Thais with Type 2 Diabetes
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Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes Porntip Tachanivate**, Runya Phraewphiphat**, Hataiporn Tanasanitkul,** Rungrudee Jinnawaso, ** Chatvara Areevut**, Rangsima Rattanasila,** Orawan Pichitchaipitak,** Khaemanee Jantawee,** Nampeth Saibuathong,** Sawitree Chanchat,** Araya Ha-upala,** Prapai Ariyaprayoon,** Patcharavee Tanlakit,** Piyanuch Maitreejorn,** Chanyaphat Pompantakron,** Jariya Boonpattararaksa,** Kanokporn Pabua, *** Oraluck Pattanaprateep, ** Sirimon Reutrakul, Ratanaporn Jerawatana* Abstract: Diabetes is a major health problem and economic burden around the world including Thailand. Patient self-management is an important key to help patients control their disease and prevent complications. This study aimed to evaluate a self-management education program in Thais with type 2 diabetes. A retrospective cohort study was performed in 488 people with type 2 diabetes attending the diabetes self-management education program by multidisciplinary team and 488 people who did not attend the program. Mean differences in hemoglobin A1c and diabetes medication utilization as dispensed from the hospital’s pharmacy (adjusted to define daily dose) between baseline and follow ups were computed using mixed-effect regression analyses. Cost-benefit was analyzed as a difference between the direct cost of conducting the program and the benefit. Satisfaction, diabetes knowledge and behavioral changes were collected in the intervention group. Results revealed that during the two-year follow up, mean differences in hemoglobin A1c reduction were similar between the two groups. However, the intervention group had a statistically significant reduction in diabetes medication utilization, compared to non-intervention group, especially during the second year. Cost-benefit analysis demonstrated that the diabetes self-management education program provided a cost saving. The intervention group increased their diabetes knowledge, changed diabetes self-care behaviors, and had high satisfaction with the program. Thus, this Diabetes Self-Management Education Program in Type 2 Diabetes is effective and associated with cost savings. Self-management program should be integrated as a routine nursing practice to improve outcomes in people with type 2 diabetes. Pacific Rim Int J Nurs Res 2019; 23(1) 74-86 Keywords: Cost, Cost-benefit, Effectiveness, Hemoglobin A1c, Medication utilization, Self-management education, Type 2 diabetes. Received 6 August 2017; Accepted 18 April 2018 Sirimon Reutrakul Pratuangtham, MD, CDE, Associate Professor, Division of Endocrinology, Diabetes and Metabolism University of Illinois at Chicago, USA. And Visiting Scholar Program, Department Introduction of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand. E-mail: sreutrak10800@gmail.com. Diabetes mellitus is one of the most common Correspondence to: Ratanaporn Jerawatana*, RN, MS, Dip. APAGN, non-communicable diseases affecting people around Division of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand. E-mail: ratanaporn.jer@gmail.com the world. The International Diabetes Federation **Faculty of Medicine Ramathibodi Hospital, Mahidol University, (IDF) estimated that 451 million people worldwide Thailand. 74 Pacific Rim Int J Nurs Res • January - March 2019
Porntip Tachanivate et al. had diabetes in 2017 and the number is expected to Review of Literature rise to 693 million by 20451. Unfortunately, most people with diabetes live in low- and middle-income DSME provides people with diabetes and countries. Uncontrolled diabetes can lead to macrovascular caregivers or family members with knowledge and and microvascular complications, including stroke, skills to perform self-care and lifestyle changes in heart disease, blindness, renal failure, and lower limb order to manage diabetes more effectively2. In a amputation2. In 2017 an estimated 5.0 million deaths systematic review, DSME was associated with a worldwide were directly caused by diabetes1. World significant reduction in hemoglobin A1c (Hb A1c) Health Organization (WHO) reported that 2.2 million levels, a marker of glycemic control, by 0.57%. 10 deaths were attributable to high blood glucose3. If maintained in the long term, this could translate to Diabetes also causes a significant economic burden. a significant decrease in complications since a 1% In 2012, an estimated 245 billion USD was spent on reduction in HbA1c was associated with 25% diabetes in the United States alone4. Thailand, an reduction in microvascular complications and 21% upper-middle income country, experiences a similar for death-related to diabetes8. In addition, a meta- burden from diabetes. The prevalence has risen from analysis of randomized controlled trials found that 7.5% in 2009 to 8.9% in 2014 5,6. The cost of diabetes the delivery of DSME program was cost-effective.11 care in 2010 was estimated at 906,374 USD in Hendrie and colleagues 12 studied the cost and Thailand or 11% of the total global health expenditure7. effectiveness of the diabetes management education The most recent survey in 2014 revealed that only program (DMEP) in person with type 2 diabetes. 23% of people with type 2 diabetes were considered The cost for the 6 month intervention period was 356 under good glucose control6. USD per person. They found that an individualized Strong evidence suggests that good glucose DMEP was effective in reducing the number of control can significantly reduce or delay microvascular hyperglycemia and hypoglycemia episodes with complications.8 While there are numerous available incremental cost effectiveness ratio (ICER) of 39 diabetes medications, lifestyle modification consisting USD per glycemic-symptoms day avoided, compared of diet and exercise remains a cornerstone in achieving with usual care. The study by Prezio and colleagues good glycemic control.2 The person’s knowledge and 13 explored the long term effects of DSME intervention ability to self-manage their disease is a vital part of program led by community health worker in uninsured diabetes care. Therefore, it is recommended that people Mexican Americans on health outcomes and cost with diabetes receive Diabetes Self-Management effectiveness. The results revealed a significant Education (DSME), usually delivered by diabetes reduction in HbA1c levels and development of foot educators or a multidisciplinary team, to enhance ulcers, compared to usual care. There was an average essential skills and knowledge in managing their of 0.056 quality-adjusted life year (QALYs) gained diabetes2. As medication cost contributes to a significant per person over 20 years with an ICER of 355 USD expense in diabetes care, patients who are empowered per QALY, compared with usual care. 13 in their self-care and adopt a healthy lifestyle could Despite the growing burden of diabetes care lead to reduced medication utilization2. This, along and evidence supporting the effectiveness of DSME, with potential reduction in complications as a result such programs in Thailand are not uniform and the of improved glycemic control, can lead to cost savings. national standard has not been established.14 A few Therefore, cost benefit analysis and medication utilization studies have explored the efficacy of DSME programs should be a part of DSME program’s evaluation9. in Thailand, up to 6-month follow up. There were Vol. 23 No. 1 75
Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes three studies that found a significant reduction in Study Aim: HbA1c levels, between 0.14-0.59%. 15-17 But, the The aim of this study was to evaluate the other studies did not find improvements.18-19 Self- effectiveness of the structured DSME program on efficacy, self-management, knowledge and quality cost-benefit, medication utilization, glycemic control, of life increased.18,19 Wattana and colleagues 16 studied diabetes knowledge, behavioral changes and satisfaction the effects of a DSME program on glycemic control, in Thais with type 2 diabetes in a tertiary medical coronary heart disease risk, and quality of life in 147 center in Thailand. persons with type 2 diabetes. The findings indicated that the intervention group, who received DSME Methods program, had a significant reduction in HbA1c level and coronary heart disease risk, and an increase in Design: Economic evaluation research design quality of life compared to the non-intervention group. by a retrospective cohort study was used. Another DSME program study in Thais with type 2 Sample and Setting: Participants in this study diabetes by Jaipakdee and colleagues15 found that the had type 2 diabetes and were being followed up at DSME program was associated with a significant one university hospital in Bangkok, Thailand from reduction in HbA1c level (-0.14%), fasting plasma January 2014- December 2015. The inclusion criteria glucose (-6.37 mg/dl), along with an increase in including having HbA1c values at follow up by health behavior scores and quality of life. attending physicians at least once during this period. When evaluating for health economic aspects, Exclusion criteria were people with non-type 2 four approaches are available20, cost-minimization, diabetes (i.e. gestational diabetes, type 1 diabetes, or cost-benefit, cost-effectiveness, and cost-utility analysis. other types of diabetes) and those without HbA1c Each of these methods has the same input and cost. values. The intervention group was composed of The four techniques are different in output or outcome; same outcome for cost-minimization, benefits in those who met the inclusion criteria and attended monetary term for cost-benefit analysis, efficacy or the DSME program in addition to routine care. The effectiveness in natural units (e.g. life years gained or non- intervention group was composed of those who clinical values) for cost-effectiveness analysis, and met the same inclusion criteria but received only natural units adjusted by utility (e.g. quality-adjusted routine care without DSME program. life years (QALYs) or disability- adjusted life years During this period, there were 613 people (DALYs) for cost-utility analysis. However, there has with type 2 diabetes who received the DSME program. not been a study evaluating cost-benefit of such programs Of these, 448 met all the inclusion criteria and were in Thailand, or a study with a longer follow up period. allocated to the intervention group. The non-intervention This is an essential component of the program’s evaluation, group was retrieved by electronic medical records. especially at the current study site which is a tertiary For this, electronic medical records from January care hospital in a university setting, providing care 2014- December 2015 were searched for persons for over 10,000 people with diabetes each year. with diagnosis code ICD-10 E1. This yielded 11, Research Question: 134 persons. They were matched with each individual Is structured DSME program in Thailand in the intervention group at a 1:1 ratio by age (± 5 years), associated with cost savings, reduced medication gender and the same time of follow up at the clinic. utilization, improved glycemic control, increased In addition, further matching of HbA1c levels was diabetes knowledge, behavioral changes and satisfaction attempted to minimize the differences between the in people with type 2 diabetes? two groups. The sample and setting are shown in Figure 1. 76 Pacific Rim Int J Nurs Res • January - March 2019
Porntip Tachanivate et al. Figure 1 Flow of the study Ethical considerations: The study protocol diabetes knowledge scores (before and after the was approved by the Institutional Review Board Committee, class), satisfaction scores, and whether they met their Faculty of Medicine Ramathibodi Hospital, Mahidol behavioral goals upon follow ups. Ramathibodi’s University. (The approval number COA no. 04-59-60, Diabetes Self-Management Education record form date May 13, 2016). developed by two advanced practice nurses (APNs) Instruments and outcomes Measure: and one physician who specialized in diabetes for use Medical records of the intervention groups in routine practice in DSME program, consist of 4 were retrospectively reviewed regarding their parts: Vol. 23 No. 1 77
Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes 1) Personal information sheet, used to amount of drug per item) / World Health Organization obtain data on the demographic characteristic such as (WHO) DDD; where WHO DDD is the assumed age, sex, education background, duration of disease, average daily maintenance dose for a medication complications, comorbidities including the diagnoses utilization for its main indication in adults, of hypertension, dyslipidemia, diabetes retinopathy independently of price and dosage form.21 and ischemic heart disease/ stroke. Cost of daily diabetes medications per patient 2) DSME/S sheets, used to obtain data on was calculated at 8 time points. The direct cost of any prior diabetes education, outline the DSME conducting the DSME program was calculated as contents along with behavior goal setting/ evaluation. cost per patient per program and consisted of the 3) Satisfactory evaluation sheet, a one-item following: facility cost, teaching supplies, office survey asking the participants to rate their overall equipment, telephone follow-up cost, staff’s salaries satisfaction of the program with a score ranging from and data management cost. Other potential costs 0 to 5, with 5 being most satisfied. including pre and post admission costs were not 4) Diabetes knowledge assessment (pre/ included in this analysis. posttest), simple 10 multiple choices/ true-false Intervention: The DSME program activities questions (total 10 points) to assess the participants’ are shown in Table 1. The program was delivered by diabetes knowledge before and after the session. a multidisciplinary team including endocrinologists, Higher scores indicate higher knowledge. The reliability two APNs, staff nurses, and dieticians. The content measured using Kuder-Richardson (KR-20) formula was based on the 7 skills of self-management, in 30 persons with type 2 diabetes was 0.80. The including healthy eating, being active, monitoring, content of Ramathibodi’s DSME record form was taking medications, problem solving, reducing risks, validated by a endocrinologist, two advanced practice and healthy coping, as defined by the American nurses and a nursing faculty who specialized in Association of Diabetes Educators9. Delivery techniques diabetes care were a combination of lecture-based strategy and HbA1c levels were obtained from laboratory individual assessments. The content took approximately database of the same university hospital. HbA1c half a day to deliver, after which the participants were assays were performed using the Turbidimetric given 1-2 behavior goals according to their medical inhibition immunoassay (TINIA) method, which has and personal needs. The participants were then asked been certified by where there have a standardization to follow up within 2-3 months, usually with their and quality control from the National Glycohemoglobin next physician appointments. During the follow up Standardization Program (NGSP). The unit of visits, they met with an APN to discuss the individual measurement was reported in percent (%). goal achievements and assess any barriers. The APN Diabetes medications used (i.e., drugs under continued to empower and motivate any further the Anatomical Therapeutic Chemical group A10A behavioral changes as needed, or encourage the or A10B), both oral and injectable forms, were participants to maintain their self-care behaviors. obtained from the electronic medical records. This Lastly, additional information and resources, and was derived from the actual filled medications at the plan for the future self-care goal were offered as hospital’s pharmacy. It was a normal practice for needed. The patients continued to receive their usual most, but not all patients at our hospital. The diabetes care from their physicians during this period medication utilization was adjusted to defined daily (Table 1). dose (DDD). DDD was calculated as (items issued x 78 Pacific Rim Int J Nurs Res • January - March 2019
Porntip Tachanivate et al. Table 1: Content and activities of the DSME program Session/time Content/Activity Multidisciplinary (7skill of self-management) FIRST VISIT Session1 (30 min) Activity: Lecture with PowerPoint presentation. Question and Endocrinologist answer session at the end, using two way communication APN -What is diabetes? Content: The pathophysiology of diabetes , complications, treatments, -Reducing risks self-management, sick day care, Immunization, reducing risk and monitoring Session 2 (30min) Activity: watching VDO on foot care Nurse -Foot care Content: Diabetic foot complication and foot care Foot care VDO Session 3 (30min) Activity: Exercise practice led by APN, along with supplemental APN exercise VDO Exercise VDO -Being active/Exercise Content: The benefits of exercise and physical activity, type of exercise, discussing barriers, exercise cautions, encourage participants to choose an appropriate exercise/physical activity, and practice exercising Session4 (70 min) Activity: Skill training / practice Multidisciplinary (15 min/station) Content: participants were divided into 4 groups for skill training -APN and practice. Each station contains behavior assessments, barriers -Nurses 4 training stations and facilitator evaluation, educating and skill training based on -Dieticians -Healthy eating individualized needs. -Taking medication Healthy eating: Food 24 hr recall, food exchange, healthy plate, -SMBG/hypoglycemia and individualized meal plan. (Monitoring) Taking medication: Action of oral medications and insulin as -Foot screening used by the participants, food and drug relationship, proper (Monitoring) medication taking and compliance, insulin injection techniques. SMBG/hypoglycemia: SMBG skill and technique, interpret and record SMBG data, hypoglycemia recognition and treatment: 15 -15 rule, preventing and monitoring hypo/hyperglycemia. Foot screening: risk assessment of diabetic foot ulcer, self-monitoring skill. Those deemed at high risk of diabetic foot complication were referred to surgical clinic specializing in diabetic foot at the same hospital Session 5 (10 min) Goal setting: two behavioral goals were set in mutual agreement Multidisciplinary with each participants. These goals were based on individual -APN -Problem solving problems as evaluated from the sessions. One goal is typically -Nurses -Healthy coping related to dietary intake, and the other was based on individual -Dieticians -Reducing risks needs. The participant received a short note containing these goals as a reminder. Participants completed knowledge assessment test and satisfaction survey before leaving. SECOND VISIT (FOLLOW UP VISIT: in 2-3 months) Session 6 (30 min) Follow up: discuss the individual goal achievements and assess APN any barriers. APN continued to empower and motivate any further -All skill evaluation behavioral changes as needed, or encourage the participants to maintain their self-care behaviors. Additional information and resources, and plan for the future self-care goal were offered as needed. Vol. 23 No. 1 79
Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes Data collection the DSME program as input or incremental cost, and difference of diabetes medication cost in monetary Since this study was a retrospective cohort study term as outcome or incremental benefit. The direct cost all information was extracted from medical records. included the staff’s salaries, calculated in proportion Data related to personal information was extracted to the time they devoted to the program, facility cost, once at the beginning of the first visit (session 1-4 and any miscellaneous cost of conducting the program. of the program). The diagnoses of hypertension, The difference between the incremental benefit and dyslipidemia, diabetes retinopathy and ischemic heart the incremental cost was then calculated per person and disease/ stroke were obtained from ICD10. Diabetic compared. In detail, the incremental benefit was the knowledge was obtained before and after the first difference in diabetes medication cost between baseline visit of the program, whereas satisfaction with the and 24 months in the intervention and non-intervention program was obtained at the end of the program. HbA1c groups, as follows: [(average daily medication cost in levels, diabetes medication utilizations were extracted the intervention group at 24 month - baseline) - (average from medication records every 2-3 months at the time daily medication cost in the non-intervention group at of follow up till 24 months for eight times. Estimated 24 month- baseline)] x 730. Costs are expressed in Thai glomerular filtration rates (eGFR) were extracted from Baht (THB) and converted to USD using 35 Baht/US$22. laboratory database. In addition, one-way sensitivity analysis was Statistical analyses: performed by varying the cost of diabetes medications Data are presented as mean ± SD or frequency (generic vs. original formula), staff salaries (±10%), (%). Independent t-tests or Chi square were used to facility cost (±10%), and the number of patients (±10%). compare differences in characteristics between groups, as appropriate. Results Mixed-effect regression analyses were performed, adjusting for hypertension and dyslipidemia, to evaluate The study flow chart is shown in Figure 1 and the mean differences (MD) between intervention and the characteristics of the participants in the intervention non-intervention groups in their changes in HbA1c and non-intervention group are shown in Table 2. levels and DDD between baseline and each time point. There were no statistically significant differences between The analyses were performed using Stata, version 14.2. groups with the exception that more participants in Cost-benefit analysis was performed from the the intervention group had retinopathy than those in hospital perspective to compare direct cost of conducting the non-intervention group (p
Porntip Tachanivate et al. For the intervention group, diabetes knowledge up period, while the non-intervention group had an increased significantly after the education session increase. The intervention group had a significant reduction (8.9 ± 2.0 vs. 9.9 ± 1.4, p
Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes 0.1 0.05 0 Changes in DDD 0 3 12 15 18 21 24 month -0.05 6 9 -0.1 -0.15 -0.2 Non-intervention Intervention * p
Porntip Tachanivate et al. generic vs. original formula, saving 202.84 THB increase in diabetes medication utilization, especially (approximately 6 USD) vs. 16.516.62 THB (approximately during the second year. This is consistent with a known 472 USD). The savings did not vary greatly when progressive nature of type 2 diabetes mellitus. While considering staff’s salaries, facility cost and the number the actual reasons for a lesser increase in medication of the patients (±10%). utilization in the intervention group were not explored in this study, this was likely due to behavioral changes Discussion and a better understanding of their diabetes, as reflected by increased diabetes knowledge and reportedly meeting In this retrospective cohort study of 976 people the behavioral goals among the participants (although with type 2 diabetes in a tertiary care setting in Thailand, the details of how each participant monitored their diabetes we found that those receiving structured DSME had were not available). Previous research demonstrated improved glycemic control, which was sustained that that DSME led to better self-care including diet, during a 2-year follow up, similarly to those who did exercise and improved medication adherence26. Reduction not receive DSME but were receiving care at the in medication utilization could be possibly associated same facility during the same period. However, the with less adverse effects including hypoglycemia, DSME program was associated with a reduction in which should be explored in future studies. daily diabetes medication utilization, and cost savings Given the reported average cost of diabetes of 3,135.08 THB/person/program (approximately care in Thailand between 1,328- 6,331 THB per patient 90 USD) over the 2-year period. Additionally, satisfaction per year (37.94-180.89 USD)7,27, this cost-saving with the program was high, diabetes knowledge increased, could be quite significant, especially if confirmed in and behavioral goals were met in a majority of the a larger study involving other health care facilities in participants. This result supported the feasibility, the country. This saving varies depending upon the effectiveness and cost-benefit of a structured DSME formula of the medications, which in this study was program in Thailand, an upper-middle income calculated as the actual medication cost, and to a lesser country with growing burden of diabetes care. degree the administrative cost of the program delivery. In the current study, the degree of glycemic This finding was consistent with those previously improvement associated with DSME, 0.6-0.7% reduction reported in Mexican Americans that diabetes education in HbA1c, was similar to those previously reported in delivered by community health workers was associated Western countries10, as well as in Thailand.16 This effect with an incremental cost-effectiveness ratio of USD size could translate into a significant reduction in 355 per quality-adjusted life year gained13, attributed microvascular complications if maintained in the by better glycemic control, lower foot ulcerations and long term8, and is equivalent to the potency of some amputations. In our study, only medication utilization of diabetes medications.2 The efficacy was maintained was considered, therefore, the potential savings could during the 2-year follow up, which consistent with include further reduction in complications and some previous studies23,24, although not all demonstrated hospitalization cost, especially if the glycemic control such long-lasting effects.25 However, the glycemic is maintained. This should be further explored. improvement seen in the intervention group was not Strengths and Limitation: different from those not attending DSME but who Our study has strengths of being the first to were receiving care at the same hospital. The improvement explore the cost-saving of DSME program in Thailand, in glycemic control in the non-intervention group, including a relatively large number of participants, however, was achieved at the expense of a continuous and a follow up period of 2 years. However, there are Vol. 23 No. 1 83
Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes limitations. This was not a randomized controlled trial Implications for Nursing Practice: as we did not feel that not delivering DSME in research The diabetes self-management education participants was appropriate. Despite the attempt to match program should be a part of diabetes care in hospitals the participants, the intervention groups appeared to at all levels in Thailand, and should be adopted as a have more severe disease, as they had more medication policy at the national level. Currently, some hospitals utilization at baseline despite having similar HbA1c have diabetes nurses or advance practiced nurses but levels to the non-intervention group. Nevertheless, some do not. However, to provide effective DSME, the study revealed that they had a smaller increase in all hospitals should be staffed with a diabetes nurse, their medication utilization over the two-year period, along with a multidisciplinary team, who are trained compared to the non-intervention group. Data on in diabetes self-management education and support. diabetes medication utilization were not available in This will allow individualized support for people all participants, which could be due to the fact that with diabetes as they have different characteristics, they were diet-controlled or received their medications problems and need different nursing interventions. outside our hospital. However, the numbers of participants The current program could also serve as a model of without medication utilization information were similar care for other chronic diseases. between the two groups. Nonetheless, the study demonstrated effectiveness of the DSME program in Acknowledgements our patient group. In addition, the current structured DSME program was established in late 2013. Prior The authors acknowledge the contributions of to that, DSME was delivered but not in a systematic the experts and health care providers who were fashion. We could not exclude the possibility that the involved in this study. We also thank the participants non-intervention participants had received DSME in this study. prior, or from other sources outside the program. The expense of the program also did not include indirect Reference costs from the patients and their families. The study was 1. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes conducted in only one tertiary medical center and the JD, Ohlrogge AW, et al. IDF Diabetes Atlas: Global estimates findings may not be generalized to other patient groups. of diabetes prevalence for 2017 and projections for 2045. Lastly, other outcomes such as quality of life or other Diabetes research and clinical practice. 2018. complications were not explored in the current study. 2. American Diabetes Association. Standards of medical care in diabetes-2017. Diabetes Care. 2017;40:S1-S142. Conclusion 3. World health organization. Global report on diabetes 2016. [cited 2017 March13]. Available form http://apps.who. A structured DSME program in Thailand was int/iris/bitstream/10665/204871/1/9789241565257 associated with a slower increment in diabetes medication 4. Centers for disease control and prevention. diabetes 2014 utilization and cost-savings, along with increased patients’ report card. .[cited 2017 April 4]. Available form http:// www.cdc.gov/diabetes/pdfs/library/diabetesreport diabetes knowledge and satisfaction. This could serve card2014.pdf as a model for developing countries where diabetes 5. Aekplakorn W, Chariyalertsak S, Kessomboon P, continues to be a significant health and economic burden. Sangthong R, Inthawong R, Putwatana P, et al. Prevalence Further research should explore the benefit of such and management of diabetes and metabolic risk factors in program in other parts of Thailand, along with other Thai adults: the Thai National Health Examination Survey outcomes such as complications and quality of life. IV, 2009. Diabetes Care. 2011;34(9):1980-5. 84 Pacific Rim Int J Nurs Res • January - March 2019
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Effectiveness of Diabetes Self – Management Education in Thais with Type 2 Diabetes ประสิทธิผลของโปรแกรมการสร้างความรูแ้ ละทักษะการดูแลตนเองในผูเ้ ป็น เบาหวานชนิดที่ 2 ของไทย พรทิพย์ เตชะนิเวศน์** รัญญา แพรวพิพัฒน์** หทัยพร ธนาสนิทกุล** รุง่ ฤดี จิณณวาโส** ฉัตรวรา อารีวฒ ุ *ิ * รังสิมา รัตนศิลา** อรวรรณ พิชติ ไชยพิทกั ษ์** แขมณี จันทร์เทวี** น�ำ้ เพชร สายบัวทอง** สาวิตรี ชาญชาติ** อารยา หาอุปละ** ประไพ อริยประยูร** พัชรวีร์ ทันละกิจ** ปิยานุช ไมตรีจร ** ชัญญาพัชร์ พรหมพันธกรณ์** จริยา บุญภัทรรักษา** กนกพร พาบัว** อรลักษณ์ พัฒนาประทีป** สิริมนต์ ริ้วตระกูล ประเทืองธรรม รัตนาภรณ์ จีระวัฒนะ* บทคัดย่อ: โรคเบาหวานเป็นปัญหาสุขภาพ และภาระเศรษฐกิจทั่วโลกและประเทศไทย การดูแล จัดการตนเองของผู้เป็นเบาหวานเป็นกุญแจส�ำคัญในการควบคุมโรค และป้องกันภาวะแทรกซ้อน การ วิจัยนี้เพื่อศึกษาประสิทธิผลของโปรแกรมการสร้างความรู้และทักษะการดูแลตนเองในผู้เป็นเบาหวาน ชนิดที่ 2 เป็นการศึกษาวิเคราะห์ยอ้ นหลังในผูเ้ ป็นเบาหวานชนิดที่ 2 จ�ำนวน 488 รายทีเ่ ข้ารับโปรแกรม โดยทีมสหสาขาวิชาชีพ และผู้ที่ไม่ได้รับโปรแกรม เพื่อเปรียบเทียบค่าน�้ำตาลเฉลี่ยสะสม และการใช้ยา ของผูป้ ว่ ย (แปลงเป็นหน่วยขนาดยามาตรฐานต่อวัน) ระหว่างก่อน และหลังเข้าโปรแกรม ความคุม้ ค่าของ การบริการ และเก็บข้อมูลความพึงพอใจ ความรู้ และการปรับเปลีย่ นพฤติกรรม วิเคราะห์ขอ้ มูลโดยสถิติ ถดถอยการเปรียบเทียบตัวแปรแบบผสม ผลการศึกษาพบว่าหลังได้รับโปรแกรม 2 ปี ค่าน�้ำตาลเฉลี่ยสะสมลดลงใกล้เคียงกันทั้ง 2 กลุ่ม กลุ่มที่ได้รับโปรแกรมมีการใช้ยาเบาหวานลดลงอย่างมีนัยส�ำคัญเมื่อเทียบกับกลุ่มที่ไม่ได้รับโปรแกรม โดยเฉพาะในปีที่ 2 โปรแกรมนี้ประหยัดค่าใช้จ่ายเมื่อเทียบต้นทุนและประโยชน์ที่ได้รับ กลุ่มที่ได้รับ โปรแกรม มีความรู้เพิ่มขึ้น มีการปรับเปลี่ยนพฤติกรรมการดูแลตนเอง และมีความพึงพอใจสูงขึ้น ดังนั้น โปรแกรมการสร้างความรู้และทักษะการดูแลตนเองในผู้เป็นเบาหวานมีประสิทธิภาพและลดค่าใช้จ่าย จึงควรบูรณาการโปรแกรมนี้สู่การปฏิบัติการพยาบาล เพื่อพัฒนาผลลัพธ์ในการดูแลผู้เป็นเบาหวาน ชนิดที่ 2 Pacific Rim Int J Nurs Res 2019; 23(1) 74-86 ค�ำส�ำคัญ: ค่าใช้จ่าย, ความคุ้มค่าของการบริการ, ประสิทธิผล, ค่าน�้ำตาลเฉลี่ยสะสม, การใช้ยา, สร้างความรู้และทักษะการดูแลตนเอง, เบาหวานชนิดที่ 2 สิรมิ นต์ ริว้ ตระกูล ประเทืองธรรม MD, CDE, Associate Professor, Division of Endocrinology, Diabetes and Metabolism University of Illinois at Chicago, USA. และ อาจารย์ คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล ประเทศไทย Email: sreutrak10800@gmail.com. ติดต่อที่ : รัตนาภรณ์ จีระวัฒนะ* RN, MS, Dip. APAGN, คณะแพทยศาสตร์ โรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล ประเทศไทย E-mail: ratanaporn.jer@gmail.com **คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล ประเทศไทย 86 Pacific Rim Int J Nurs Res • January - March 2019
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