Diarrhoea and Constipation
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Diarrhoea and Constipation Edition 4 – June 2015 Improving life for people affected Crohn's and Colitis UK Information Sheet by inflammatory bowel diseases Diarrhoea and Constipation Introduction When we eat, food passes down the Diarrhoea is one of the main symptoms of oesophagus (gullet) and then into the Inflammatory Bowel Disease (IBD), which stomach, where it is broken down by includes Crohn’s Disease and Ulcerative gastric (stomach) juices to a porridge-like Colitis (UC). Microscopic Colitis, another consistency. form of IBD, can also cause diarrhoea. IBD treatment aims to control the symptoms and keep you in remission. Yet some people with IBD continue to have diarrhoea. This leaflet looks at why this might happen and includes some suggestions about ways to help reduce and manage diarrhoea. Some people with IBD may experience constipation. This leaflet looks at the causes of constipation, and how you may be able to alleviate it. What is diarrhoea? Diarrhoea is generally defined as passing loose watery stools (faeces, poo) at least 3 times a day. There is often a feeling of ‘urgency’, a need to rush to the toilet. Sometimes the diarrhoea can be explosive. It may also lead to bowel The partly digested food then moves into incontinence with a leakage of faeces. the small intestine where most of the nutrients are absorbed. If the diarrhoea lasts less than four weeks, it is usually referred to as ‘acute The waste, now a watery slurry, passes diarrhoea’. If it lasts for four weeks or into the colon. It is here that most of the more, it is generally thought of as ‘chronic’ water is normally absorbed so the waste (ongoing) diarrhoea. can form solid stools (faeces). These collect in the last part of the colon and the Diarrhoea happens when the colon (large rectum and are passed out of the body in intestine or large bowel) cannot absorb all a bowel movement. the fluid produced during the digestive process. Diarrhoea is a common symptom of IBD affecting the large bowel. During a flare- As shown in the diagram, the up, the cells in the lining of the colon gastrointestinal (digestive) tract is a long become inflamed and do not work tube that starts at the mouth and ends at properly. The colon cannot absorb all the the anus. fluid and the stools remain loose and watery, or even entirely liquid – and this is experienced as diarrhoea. Crohn’s and Colitis UK, 4 Beaumont House, Sutton Road, St Albans, Hertfordshire AL1 5HH Information Service: 0845 130 2233 Email: enquiries@crohnsandcolitis.org.uk Website: www.crohnsandcolitis.org.uk Charity registered in England and Wales Number 1117148 and in Scotland Number SC038632 A company limited by guarantee in England: Company number 5973370
Diarrhoea and Constipation Edition 4 – June 2015 The looser faeces can also move more However, if part of the ileum is lost, rapidly through the colon, causing more much higher levels of bile salts can frequent bowel movements. drain into the colon. This can irritate the colon causing watery diarrhoea. What causes diarrhoea? Inflammation of the end of the ileum If you have IBD, your diarrhoea may be can also lead to bile salt diarrhoea as due to a flare-up of your disease - well as to poor fat absorption (see although there are also some other factors below). which may be causing the diarrhoea or making it worse. Malabsorption of fats - If you have Crohn’s in the ileum (the lower part of Side effects of drugs for IBD - One of the small intestine) you may have the rare side effects of 5-ASAs such as difficulty absorbing fats. This can lead mesalazine and sulphasalazine, is to urgency and to pale and bad watery diarrhoea. You may be able to smelling, poorly formed faeces that are reduce this side effect by taking the difficult to flush away. tablets with or after food. Some of the immunosuppressants, such as Iron Supplements - You may be azathioprine and methotrexate, can prescribed iron supplements for also cause diarrhoea especially during anaemia caused by your IBD. A the early weeks of treatment. Talk to change in bowel habit is a common your doctor or IBD team about ways to side effect of iron supplements and manage this, or see our Drug while some people get constipation, Treatment leaflets, Azathioprine and others get diarrhoea. Methotrexate, for further information. Irritable Bowel Syndrome (IBS) - IBS Side effects of other drugs - You may is sometimes confused with also find it helpful to check whether Inflammatory Bowel Disease, but is a diarrhoea is a side effect of any other separate and different condition. Some medications you are taking. Antibiotics of the typical symptoms of IBS, such as and acid-lowering treatments, such as diarrhoea and colicky pain, can be very omeprazole and lansoprazole, can also similar to those of IBD, but IBS does cause diarrhoea. not cause inflammation or bleeding. However, it is possible that some Colectomy and ileo-rectal people with Ulcerative Colitis or Crohn’s anastomosis - In this operation the Disease may have irritable bowel colon is removed and the ileum (the symptoms as well as IBD – probably lower part of the small intestine) is because the inflammation has joined directly to the rectum. After this temporarily affected the nerve endings procedure, your faeces will tend to be in the bowel. So they may, for much more liquid because you no example, continue to experience longer have a colon to absorb the diarrhoea following an IBD flare-up, water. even when the inflammation has died down. Small bowel surgery for Crohn’s Disease - If you have had the end of the ileum (the lower part of the small intestine) removed, you may have bile salt diarrhoea. Bile salts are produced in the liver and are usually reabsorbed in the ileum, so that only very small amounts enter the colon. 2
Diarrhoea and Constipation Edition 4 – June 2015 Diet and food sensitivities - Some Antidiarrhoeal drugs - Antidiarrhoeals people are sensitive to particular foods, work by slowing down the contractions such as milk and wheat. Too much (muscle movements) of the gut, so that fibre, spicy food, chocolate, caffeine (in the food takes longer to pass through coffee, tea and cola drinks), alcohol, your system. This allows more time for fructose (a sugar in fruit) and artificial the water to be reabsorbed and for the sweeteners (sorbitol) can all have a stools to become firmer and less laxative effect, stimulating and urgent, but should generally loosening the bowels. Intolerance to be avoided if your large bowel is lactose, a natural sugar found in milk, affected by your IBD (see below). can cause diarrhoea. If you are Loperamide (Imodium, Arret) is a concerned about diet and food commonly used and effective sensitivities, ask your IBD team to refer antidiarrhoeal drug. It is long-acting you to a dietitian. and usually only needs to be taken once or twice a day, although it can be Infections - In people without IBD, taken more often if needed. Other diarrhoea can often be a sign of: antidiarrhoeals such as diphenoxylate (Lomotil) and codeine may need to be gastroenteritis – an infection of the taken three or four times a day. large bowel, commonly caused by The patient information leaflets that a virus or bacteria or, come with all antidiarrhoeals advise against taking them if you have IBD, Clostridium difficile (also known as particularly if you are having a flare-up C. diff) – a type of bacterial of UC. This is because there are risks infection that can affect the of side effects, including toxic digestive system. megacolon (when digestive gases get trapped in the colon, making it swell These infections can also affect people up) associated with taking these drugs. with IBD and your doctor or IBD team So, whichever condition you have, if may carry out tests to make sure your you are having an acute or severe diarrhoea is not at least partly due to flare-up, do not take any antidiarrhoeal such infections. medicines without first checking with your doctor or IBD team. What treatment can I take? Drugs used to treat active IBD – A range of drugs are used to treat IBD Antispasmodic drugs - These work by relaxing the intestinal muscles to and then to help maintain remission slow down bowel movements in a way once it is under control. If you are on that not only helps to relieve diarrhoea, such medication, you should find your but also the cramping pain often diarrhoea lessens as the drugs accompanying diarrhoea. Brands prescribed for your IBD take effect. include Buscopan and Colofac. They Some drugs, such as 5-ASAs and are usually safe to take, but check with steroids, tend to act quickly while your doctor first. others, such as azathioprine and methotrexate, take much longer to work. As mentioned earlier, some Bile salt drugs - These include people may get diarrhoea as a side colestyramine (Questran) and effect of these medications. If you do colestipol (Colestid) which come in continue to have a flare-up or to powder or granule form, and a newer experience serious diarrhoea, you may drug, colesevelam, which comes as need to change your medication. Talk tablets. to your specialist about this. 3
Diarrhoea and Constipation Edition 4 – June 2015 These bile salt drugs absorb the Eating overflow bile salts, preventing them Eat small, frequent meals. reaching the colon and causing Keep a food diary and note down any diarrhoea. They can affect the foods that seem to upset you, so you absorption of other drugs that you may can avoid them. However, it is not be taking for your IBD. If you are advisable to cut out too many food taking other drugs, it is worth checking groups, and if you find you are with your IBD team whether they will avoiding many different types of food, be affected by the bile salt drugs, and it may be helpful to consult a dietitian if so, how you can manage taking both. to help you balance your diet. There is also an alternative ‘lite’ Some sensitivities might be only version of colestyramine available, but temporary and you may be able to re- this can cause these side effects too. introduce that food at a later date. If If you are taking colestyramine and your diarrhoea is worse after you have have experienced side effects, it may eaten foods containing gluten (a be worth asking if you can try the lite protein found in wheat, barley and rye) version as in some people this causes it may be due to an intolerance to fewer side effects. gluten. But it could also be a sign of coeliac disease. This is a condition in Bulking agents - Bulking agents or which the immune system mistakes ‘bulk formers’ are made from a type of substances found inside gluten as a plant fibre (usually ispaghula or threat to the body and attacks them. sterculia). Popular brands include This damages the surface of the small Fybogel and Isogel. These come as bowel (intestines) disrupting the body's granules which, when taken with plenty ability to absorb nutrients from food. of water, swell up inside the bowel, There are tests to diagnose coeliac thickening liquid stools or softening disease. If you are concerned that hard stools and so providing the bulk foods containing gluten are affecting needed for the bowel to work more you, speak to your IBD team to see if normally. Bulking agents can be they can refer you to a dietitian. useful for both diarrhoea and For many people, foods rich in fibre constipation. They are generally safe tend to make diarrhoea worse. Don’t for people with IBD, although they may give up all fruit and vegetables, but try cause bloating and wind, but should be cutting down on high fibre foods such avoided if you have a stricture as bran cereal, pulses (peas and (narrowing) of the bowel, as beans) and the type of fruits or sometimes happens with Crohn’s vegetables usually eaten with the Disease. skins, pips and seeds. Onions can be particularly troublesome. You can find further information on all Avoid hot or spicy foods, if they don’t these types of drugs in our booklet Drugs agree with you. used in IBD and our individual drug If milk makes your diarrhoea worse, try treatment information sheets. using a lactose free milk and avoiding foods made with milk such as custards Can changing what I eat and drink and sauces. Some medicines also help? contain lactose, but do not stop taking You may find that you have diarrhoea any prescribed medication without whatever you eat or drink, but some checking with your IBD team. people find altering their diet helps to Chicken and rice soup is a traditional reduce diarrhoea. Everyone is different remedy for diarrhoea, which some and what works for others may not work people have found useful. for you. However, the following suggestions may be of some assistance. 4
Diarrhoea and Constipation Edition 4 – June 2015 Carrot soup is also said to be soothing Use moist toilet paper, damp cotton for the gut, and is rich in beta-carotene wool, or moist toilet wipes. Many baby which may promote healing. wipes contain alcohol and are best The BRAT diet, (bananas, rice, avoided, although there are now some applesauce and toast – or tea) is also ‘alcohol-free’ brands. traditionally recommended as a way of reducing acute diarrhoea. But this Whenever possible wash around the does not contain enough nutrients to anus after a bowel movement. A bidet be a healthy long term option. is ideal, but you could also use a shower attachment while sitting with Other ‘special diets’ may also reduce your bottom over the edge of the bath. diarrhoea. However, in order to make Or use a soft disposable cloth with sure that you are still getting a balanced warm water. Avoid flannels and and nutritious intake, these are best used sponges as they can be rough and are only with the advice of a qualified dietitian. difficult to keep clean. Drinking Use non-scented soap or a special Many people are sensitive to caffeine, washing solution. There are products so try opting for decaffeinated coffee, specifically developed for people with tea, and cola drinks. bowel problems. Ask your nurse about Reduce your consumption of alcohol, these or contact the Bladder and particularly beer and lager, as this is Bowel Foundation for more known to have a laxative effect. information. Avoid using antiseptics or Drinks made with artificial sweeteners disinfectants in washing water, as can also cause diarrhoea. these can sting. For more information on healthy eating Dry the area very gently, patting with with IBD see our booklet, Food and IBD. soft toilet paper or soft towel. Do not rub. If you are very sore you could use What should I do about the other a hairdryer on a low setting. symptoms which may come with diarrhoea? Use a barrier cream or ointment a little If you have diarrhoea, you will lose more at a time and rub it in gently. Large water than usual with your stools. It is amounts stop the skin from breathing therefore especially important if you have and can make the area sweaty and IBD that you drink plenty of fluids. You uncomfortable. Make sure the old may also need to replace the salts and layer of cream is washed off before sugars lost with the diarrhoea. One way applying more. Choose a simple to do this is to drink a commercial product such as zinc and castor oil. It rehydration solution such as Dioralyte, is better to avoid creams containing Electrolade or Rehydrit. lanolin, as some people are allergic to this. Other products you could try For more serious dehydration your doctor include Sudocrem, Cavilon, and may recommend drinking an Oral Metanium. Rehydration Solution (ORS) with a higher sodium (salt) level. For more details on Some people have found alternative this and how to avoid and manage products helpful, including aloe vera dehydration, see our information sheet, gel, Kamillosan Baby Cream and Dehydration. Germoline. How can I treat sore skin? Try to allow the air to get to the anal Frequent diarrhoea and wiping can irritate area for at least part of every day. the skin around the anus, making it sore. The following tips may help. 5
Diarrhoea and Constipation Edition 4 – June 2015 Try not to scratch the anal area, as this occur in Crohn’s Disease (see How will make things worse. If you find you can I treat constipation?) are scratching in your sleep, you could wear cotton gloves in bed (available Not enough fluids - If you are not from your chemist). drinking enough, this can lead to constipation as the stools become If you use a pad for incontinence, hard, dry and difficult to pass. make sure that the pad has a soft surface and that no plastic comes into Drugs - As mentioned before, contact with your skin. constipation can be a side effect of drugs, for example, anti-diarrhoeals Wear cotton underwear to allow the or codeine, which is found in some skin to breathe. Avoid tight jeans and pain killers. other clothes that might rub the area. If you wear tights, think about changing Damage to the anal muscles - A to stockings or crotchless tights. common cause of constipation in women following vaginal childbirth If you continue to feel sore, or if your skin or pelvic surgery. A special test is broken, talk to your doctor, nurse, or may be used to diagnose this. IBD team. They may be able to prescribe more effective medications. If the How can I treat constipation? soreness persists you may have a fungal You may find that drinking plenty of fluids infection (such as thrush), which will might help form softer stools which are require different treatment. easier to pass. It may also help to increase the amount of fibre in your diet, What is constipation? although this might not work for all people, Constipation can be defined as passing for example, those with strictures. Some stools fewer than 3 times per week, people may find that bulking agents, such needing to strain, or passing hard stools as Fybogel or Isogel, can soften hard which are unusually large or small. You stools, but also may not be suitable if you may find that a stool passing through an have a stricture. If you can, increase the area of inflammation in the colon can be amount of exercise you do to help with particularly painful. constipation and to speed the passage of stools through your colon. What causes constipation? Proctitis - You may be more likely Laxatives can help to relieve constipation. to have constipation if you have Osmotic laxatives, such as Movicol, are proctitis (inflammation of the usually considered the best type of rectum). laxative for people with IBD. These increase the amount of water in the large IBS - Some people with IBD bowel so that stools can be passed more experience IBS symptoms, which easily. However, laxatives can also cause can be constipation and/or wind and stomach cramps, especially at diarrhoea. the start of treatment. Low fibre diet - Fibre helps stools If you are worried about constipation and pass through the gut, so if you have how to treat it, speak to your IBD team or reduced your intake of fibre, you doctor. may find that you become constipated. Although excess fibre should be avoided if you have a stricture of your intestine, as can 6
Diarrhoea and Constipation Edition 4 – June 2015 What other symptoms may come with Help and support from Crohn's and constipation? Colitis UK Some people with constipation may All our information sheets and booklets develop associated conditions such as are available to download from our haemorrhoids (also known as ‘piles’). website: www.crohnsandcolitis.org.uk. If Haemorrhoids are swellings that contain you would like a printed copy, please enlarged blood vessels that are found contact our information line – details inside or around the rectum and anus. below. Symptoms can include: Crohn’s and Colitis UK Information bleeding after passing a stool Line: 0845 130 2233: Open Monday to itchiness around the anus Friday, 9am to 5pm, excluding English a lump hanging down outside of the bank holidays. An answer phone and anus, which may need to be call back service operates outside these pushed back in after passing a hours. You can also contact the service stool. by email info@crohnsandcolitis.org.uk or letter (addressed to our St Albans office). Initial treatments for haemorrhoids, if Trained Information Officers provide caused by constipation, are drinking callers with clear and balanced plenty of fluids, and increasing the fibre in information on a wide range of issues your diet. Although these may not be relating to IBD. suitable for everyone, particularly those with strictures (see earlier How can I treat Crohn’s and Colitis Support: 0845 130 constipation?) If these steps don’t work, 3344: Open Monday to Friday, 1 pm to you may need to be referred to a 3.30 pm and 6.30 pm to 9 pm, excluding specialist for further treatment. If you are English bank holidays. This is a concerned that you may have confidential, supportive listening service, haemorrhoids, speak to your IBD team which is provided by trained volunteers about it. and available to anyone affected by IBD. These volunteers are skilled in providing Impact of having diarrhoea and emotional support to anyone who needs a constipation on everyday life safe place to talk about living with IBD. Many people with IBD can feel embarrassed and upset about having Other support from Crohn’s and Colitis diarrhoea and constipation. But if your UK symptoms are making you feel this way, Crohn’s and Colitis UK Forum you might find that talking about it helps. This closed-group community on You may wish to talk to a professional Facebook is for everyone affected by IBD. counsellor (see our information sheet You can share your experiences and Counselling and IBD). Or you may want receive support from others at: to speak to someone who understands www.facebook.com/groups/CCUKforum what it’s like to have IBD. Our confidential listening service, Crohn’s and Colitis Other Organisations Support, is run by volunteers who have Disability Rights UK experience of IBD and are trained in 12 City Forum, 250 City Road, London, giving emotional support (see Help and EC1V 8AF Support from Crohn’s and Colitis UK). Website: www.disabilityrightsuk.org From this organisation, you can purchase You might also find it reassuring to speak RADAR keys which allow access to to other people with IBD and share specially adapted toilets. experiences through the Crohn’s and Colitis UK Facebook Forum. See Other Support from Crohn’s and Colitis UK for more details on the Forum. 7
Diarrhoea and Constipation Edition 4 – June 2015 Irritable Bowel Syndrome Network (The IBS Network) Unit 1.12 SOAR Works, 14 Knutton Road, Sheffield, S5 9NU 0114 272 3253 Email: info@theibsnetwork.org Website: www.theibsnetwork.org The IBS Network is an independent, self help organisation for people with Irritable Bowel Syndrome. The helpline is staffed by specialist IBS nurses. Crohn’s and Colitis UK 2015 Diarrhoea and Constipation – Edition 4 Last review: June 2015 Next planned review: 2017 Crohn's and Colitis UK publications are research based and produced in consultation with patients, medical advisers and other health or associated professionals. They are prepared as general information on a subject and are not intended to replace specific advice from your own doctor or any other professional. Crohn's and Colitis UK does not endorse or recommend any products mentioned. Crohn's and Colitis UK is an accredited member of the Information Standard scheme for Health and Social care information producers. We hope that you have found this leaflet helpful and relevant. If you would like more information about the sources of evidence on which it is based, or details of any conflicts of interest, or if you have any comments or suggestions for improvements, please email the Publications Team at publications@crohnsandcolitis.org.uk. You can also write to us at Crohn's and Colitis UK, 4 Beaumont House, Sutton Road, St Albans, Herts. AL1 5HH or contact us through the Information Line: 0845 130 2233. 8
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