DAILY SLEEP, WEEKLY WORKING HOURS, AND RISK OF WORK-RELATED INJURY: US NATIONAL HEALTH INTERVIEW SURVEY (2004-2008)
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Chronobiology International, 27(5): 1013–1030, (2010) Copyright © Informa UK Ltd. ISSN 0742-0528 print/1525-6073 online DOI: 10.3109/07420528.2010.489466 DAILY SLEEP, WEEKLY WORKING HOURS, AND RISK OF WORK-RELATED INJURY: US NATIONAL HEALTH INTERVIEW SURVEY (2004–2008) David A. Lombardi,1 Simon Folkard,2,3 Joanna L. Willetts,1 and Gordon S. Smith4 Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 1 Center for Injury Epidemiology, Liberty Mutual Research Institute for Safety, Hopkinton, Massachusetts, USA 2 Laboratoire d’Anthropolgie Appliquée, Université Paris Descartes, Faculté de Médecine, Paris, France 3 Body Rhythms and Shiftwork Centre, University of Wales Swansea, Swansea, UK 4 National Study Center Trauma and EMS, University of Maryland, Baltimore, Maryland, USA For personal use only. The impact on health and safety of the combination of chronic sleep deficits and extended working hours has received worldwide attention. Using the National Health Interview Survey (NHIS), an in-person household survey using a multistage, stratified, clustered sample design representing the US civilian, non-institutionalized population, the authors estimated the effect of total daily self-reported sleep time and weekly working hours on the risk of a work-related injury. During the survey period 2004–2008, 177,576 persons (ages 18–74) sampled within households reported that they worked at a paid job the previous week and reported their total weekly work hours. A randomly selected adult in each household (n = 75,718) was asked to report his/her usual (average) total daily sleep hours the prior week; complete responses were obtained for 74,415 (98.3%) workers. Weighted annualized work-related injury rates were then estimated across a priori defined categories of both average total daily sleep hours and weekly working hours. To account for the complex sampling design, weighted multiple logistic regression was used to independently estimate the risk of a work-related injury for categories of usual daily sleep duration and weekly working hours, controlling for important covariates and potential confounders of age, sex, race/ethnicity, education, type of pay, industry, occupation (proxy for job risk), body mass index, and the interaction between sleep duration and work hours. Based on the inclusion criteria, there were an estimated 129,950,376 workers annually at risk and 3,634,446 work-related medically treated injury episodes (overall injury rate 2.80/100 workers). Unadjusted annualized injury rates/100 workers across weekly work hours were 2.03 (≤20 h), 3.01 (20–30 h), 2.45 (31–40 h), 3.45 (40–50 h), 3.71 This paper was presented at the 19th International Symposium on Shiftwork and Working Time, August 2–6, 2009, Venice, Italy. Address correspondence to David A. Lombardi, PhD, Senior Research Scientist, Center for Injury Epidemiology, Liberty Mutual Research Institute for Safety, 71 Frankland Road, Hopkinton, MA 01748, USA. Tel.: (508) 497-0210; Fax: (508) 435-3456; E-mail: david.lombardi@libertymutual.com 1013
1014 D. A. Lombardi et al. (50–60 h), and 4.34 (>60 h). With regards to self-reported daily sleep time, the esti- mated annualized injury rates/100 workers were 7.89 (10 h). After controlling for weekly work hours, and aforementioned covariates, significant increases in risk/1 h decrease were observed for several sleep categories. Using 7–7.9 h sleep as reference, the adjusted injury risk (odds ratio [OR] for a worker sleeping a total of 10 h of usual daily sleep, the OR was marginally significantly elevated, 1.82 (95% CI: 0.96–3.47). These results suggest significant increases in work-related injury risk with decreasing usual daily self-reported sleep hours and increasing weekly work hours, independent of industry, occupation, type of pay, sex, age, education, and body mass Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 (Author correspondence: david.lombardi@libertymutual.com) Keywords Epidemiology; Fatigue; Injury; Sleep; Work hours INTRODUCTION The impact on health, safety, and well-being of sleep deficits and extended working hours has received increasing worldwide attention For personal use only. (Caruso et al., 2006). With respect to sleep, the evidence is growing that short sleep duration is associated with several chronic disease outcomes, such as diabetes (Gottleib et al., 2005), hypertension (Gangwisch et al., 2006), cardiovascular disease (Ayas et al., 2003), obesity (Di Milia & Mummery, 2009; Marshall et al., 2008; Singh et al., 2005), and sickness absences from work (Westerlund et al., 2008). In contrast, long sleep dur- ations have been associated with adverse mental health conditions, such as depression (Patel et al., 2006). With respect to safety, lack of sleep has been associated with traffic crashes (Connor et al., 2001; Teran-Santos et al., 1999), and work-related injuries (Dembe et al., 2005; Folkard & Lombardi, 2005). Likewise, long working hours and demanding work schedules are associated with various adverse impacts on worker safety and health (Biggi et al., 2008; Dembe et al., 2005; Esquirol et al., 2009; Hanecke et al., 1998; Lin et al., 2009; Suwazono et al., 2009). One study of a large representative sample of US workers found that working >60 h/wk increased injury hazard rates by 23% (Dembe et al., 2005), and another large German study reported an exponential increase in work “accident” risk observed beyond the 9th h of work (Hanecke et al., 1998). Injury risks associated with long work hour schedules and overtime have been shown to vary widely across a range of occupations in the USA (Dembe et al., 2008). This effect has been demonstrated across multiple industries; among manufacturing workers, for example, those who worked >64 h the week before the shift in which they were injured had an 88% excess risk compared to those who worked
Sleep, Working Hours and Risk of Injury 1015 workers, long work hours and irregular work schedules were significantly associated with a higher work-related injury rate after controlling for potential confounders (Dong, 2005). With respect to health outcomes, long working hours has also been associated with hypertension, cardiovascular disease, diabetes, and sleep disorders (Härmä, 2003, 2006). However, only a limited number of published studies that have examined the association among long work hours, sleep duration, and injury risk have controlled for important potential confounders, e.g., occupation, industry, and body mass index (BMI). Many have examined only small study populations making them vulnerable to the healthy worker effect and limited external validity (Folkard & Lombardi, 2004). Despite these limitations, there appears to be a Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 clear relationship between work hours and sleep duration, with an increase in work hours being associated with both a reduction in the opportunity to sleep and sleep quality. In one study involving 5720 Stockholm workers, high work demands and physical effort at work were found to be risk indi- cators for disturbed sleep (Åkerstedt et al., 2002), and another study of 367 forestry workers reported that long working hours led to reduced sleep, compromised recovery time, and potentially reduced work safety (Lilley et al., 2002). More recently, a study by Virtanen et al. (2009) reported that working >55 h as compared to 35–40 h/wk significantly increased by 2-fold For personal use only. the risk of shortened sleeping hours (odds ratio [OR] = 1.98, 95% confi- dence interval [CI] = 1.04, 3.77), after adjusting for demographic factors. With respect to other potential confounders in the relationship between work hours, sleep duration, and injury risk, a study of the US population using the National Health Interview Survey (NHIS) data showed a descriptive association between usual sleep duration and obesity among adults (Schoenborn & Adams, 2008). The findings of this study suggested that those sleeping 40 h/wk rose from 26% to 31%. At the same time, data from the US Centers for Disease Control and Prevention (CDC) indicates that the percent of males and females reporting an average of
1016 D. A. Lombardi et al. Sweden (Westerlund et al., 2008). We used the National Health Interview Survey (NHIS) and pooled across a large population of workers from the 5 most recent years of available data (2004–2008) to estimate the independent effect of usual daily sleep duration and weekly working hours on the risk of a work-related injury in the USA, controlling for important factors such as age, sex, race/ethnicity, education, type of pay, industry, occupation (as a proxy for job risk), body mass index (BMI), and the interaction among usual sleep duration and work hours. MATERIALS AND METHODS Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 Study Population The data analyzed in this study are from the NHIS, which is an in- person household survey with a multistage, stratified, clustered sample design that provides estimates on health indicators, health care utilization and access, and health-related behaviors of the civilian, non-institutiona- lized population residing in the 50 states and the District of Columbia in the USA. The NHIS has been a continuous nationwide sample survey since 1957 conducted by the National Center for Health Statistics For personal use only. (NCHS) to monitor the health of the population of the USA on a broad range of health topics (NCHS-NHIS, 2008). The current study was approved by the Liberty Mutual Research Institute for Safety’s Institutional Review Board and complies with the ethical requirements of the journal (Portaluppi et al., 2008). Pooling The data for this study were pooled across the 5 most recent years of the NHIS survey (2004–2008). In general, the survey questions and sampling design for these years is nearly identical. However, starting in 2006, the size of NHIS was reduced by about 13% due to budget con- straints (Chen et al., 2009), and a further cut of another 13% was made in 2008 (NCHS-NHIS, 2008). NHIS data are obtained through a complex sample design that allows for valid population estimates, assuming appro- priate adjustments are made to the statistical analysis that take into con- sideration the stratification, clustering, and weighting in the study design (NCHS-NHIS, 2008). Pooling NHIS data across years for estimation is con- sidered reliable when the proper adjustments to sampling weights are made. Sample weights were assigned by the NCHS for each respondent on the basis of the number and composition of households and included adjustment for non-response (Chen et al., 2009; NCHS-NHIS, 2008). Figure 1 describes the selection criteria and sample sizes for the pooled data used in the current study. In summary, for the years 2004–2008, the
Sleep, Working Hours and Risk of Injury 1017 Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 For personal use only. FIGURE 1 National Health Interview Survey (2004–2008). NHIS data includes 417,390 persons with complete sampling design infor- mation reported in the family survey by an adult in the household. This family survey includes injury information on 281,451 adults aged 18–74 yrs, of which 177,576 (63%) were reported to be working the previous week and average weekly working hours was available. Within each sampled household, one adult was then randomly chosen for a more detailed interview. Among these adults, 75,718 (93%) provided complete data on their usual sleep duration, and 74,415 provided complete data on both sleep and work-hour information. The primary analysis of the current study includes 69,248 subjects (91.5% of the subsample) who reported working the previous week, their weekly work hours, usual daily sleep duration, and complete covariate information.
1018 D. A. Lombardi et al. Injury Data As with the sleep duration and work hours data, injury data are ascer- tained each year (2004–2008) in the administration of the Family Questionnaire, which captures any injury or poisoning episode that a member of the household may have experienced in the 3 months prior to the interview that required medical attention (Chen et al., 2009; Smith et. al., 2006; Warner et al., 2000). This includes a phone call or visit to a doctor or a visit to a hospital, clinic, or the emergency room (outpatient). Multiple injury reports are captured in that each family member is allowed to report more than one injury or poisoning episode. Verbatim text information on each injury includes the body part and how the Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 injury happened, which are recorded for further coding at NCHS. Only injury descriptions which can be coded to the International Classification of Diseases, Clinical Modification (ICD)-9CM nature of injury codes 800–999 are included in the injury file (includes acute musculoskeletal conditions but not gradual onset conditions such as tendonitis) (NCHS, 1997; Smith et al., 2006). Although each person is allowed up to 10 sep- arate injury episodes, for the purposes of the current analysis, a person was considered injured if they had at least one injury episode reported. For personal use only. An injury was further classified as work-related based upon the response to the question, “What were you doing when the injury happened?” in which the response was “Working at a paid job.” Work Hours An employed person was defined as a subject who responded that they were “employed in a job or business during the week” before the interview. This includes those who were engaged in unpaid work in the family business or farm, excluding personal work in home. Work hours were estimated as average weekly working hours for each “employed person” reported by the randomly selected adult respondent of each household. A priori categories of weekly working hours were defined as: ≤20, 21–30, 31–40, 41–50, 51–60, and >60 h. Sleep Duration Sleep duration was introduced into the NHIS in the Sample Adult Core in 2004 using the question “On average, how many hours of sleep do you get in a 24-hour period?” The large sample size in this study allowed us to examine the effects of sleep in workers across a range of seven a priori categories defined as: ≤4.99, 5–5.99, 6–6.99, 7–7.99, 8–8.99, 9–9.99, and >10 h.
Sleep, Working Hours and Risk of Injury 1019 Covariates and Potential Confounders Our analyses controlled for sociodemographic, physical, and job factors (Dembe et al., 2008; Schoenborn & Adams, 2008; Vgontzas et al., 2008). Sociodemographic factors included age, sex, education, and race/ ethnicity (Bohle et al., 2008; Di Milia et al., in press; Folkard et al., 2008; Gander & Signal, 2008). Education was defined as the highest level of education achieved. Race/ethnicity was categorized as Non-Hispanic White, Hispanic, Non-Hispanic Black, and Non-Hispanic Other. For physical factors, BMI was obtained from the Sample Adult Core and calculated from self-reported height and weight. Job-related factors, obtained from the Sample Adult Core, included industry, occupation, Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 and type of pay (in response to the question “Were you paid hourly?”). Industry and occupation were coded by the NHIS using the North American Industrial Classification System (NAICS) and Standard Occupation Classification (SOC), respectively, based on a verbatim description of the person’s industry and occupation. We also controlled for the interaction between a priori work-hour and sleep-hour categories. For personal use only. Data Analysis To analyze the complex survey design data in the NHIS, SAS version 9.1 (SAS Inc., Cary, NC), procedures for survey data were used to incor- porate the sampling design attributes and weighting into the analyses. For descriptive analyses, SurveyMeans and SurveyFreq with corrected standard errors for mean estimation, 95% confidence intervals, weighted frequency, and percents were calculated. Weighted annualized work-related injury rates were estimated across a priori defined categories of total daily sleep hours and weekly working hours also using SAS Proc SurveyFreq. Multiple logistic regression using the SAS procedure Proc Survey Logistic was used to estimate the risk of a work-related injury (as a binomial variable) as a function of daily sleep time, controlling for weekly working hours, age, sex, race/ethnicity, education, type of pay, industry and occu- pation, BMI, and interactions. Parameter and odds ratio (OR) estimates were computed after adjustment for stratification, clustering, and unequal weighting using the method of maximum likelihood. Taylor series approxi- mations were used to compute the corrected standard errors and confidence intervals of the OR (Binder, 1983). An alpha level of .05 was use for statistical significance for parameter based on the Wald chi-square; however, sociode- mographic variables were kept in the model for adjustment, regardless of their statistical significance. To examine the interaction between total daily sleep hours and weekly working hours, a hierarchically well-formulated (HWF) logistic regression model (Kleinbaum, 1992) approach, including both lower order terms of the two-way higher order interaction, was used.
1020 D. A. Lombardi et al. RESULTS Subject Characteristics Among subjects interviewed over the 5-yr period who reported both working the previous week and average weekly work hours (n = 177,576), 54% were male and the mean (±SEM) age of the subjects was 40.6 (±0.03) yrs (Table 1). The majority of subjects were White, non-Hispanic (69.5%), followed by Hispanic (14.0%), and Black, non-Hispanic (11.2%). Table 2 presents the top 10 industries and occupational categories. Industry employment was primarily distributed among Health Care and Social Assistance (13.1%), Manufacturing (11.1%), Retail Trade (10.5%), Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 TABLE 1 Characteristics of National Health Interview Survey (NHIS): all subjects (2004–2008) Number of subjects Weighted frequency Weighted Characteristic interviewed (000s) percent Total 177,576 649,752 100.0 Sex Male 94,472 350,902 54.0 For personal use only. Female 83,104 298,850 46.0 Age (yrs) 18–24 22,321 84,669 13.0 25–34 39,944 145,705 22.4 35–44 44,850 158,742 24.4 45–54 42,809 156,371 24.1 55–64 22,952 86,396 13.3 65 + 4,700 17,869 2.8 Mean ± SEM 40.6 ± 0.03 Combined Ethnicity Non-Hispanic White 103,623 451,322 69.5 Hispanic 39,571 91,245 14.0 Non-Hispanic Black 23,620 72,946 11.2 Non-Hispanic Other 10,762 34,239 5.3 Education Did not complete High School 24,874 71,854 11.2 High School Graduate 49,687 180,545 28.2 Some College 51,151 192,979 30.2 Bachelor’s Degree 32,489 129,438 20.2 Master’s Degree 11,682 46,634 7.3 Professional Degree 4,463 17,959 2.8 Missing 3,230 Body Mass Index (BMI)a Underweight (30) 18,527 67,843 24.9 Mean ± SEM 27.3 ± 0.02 a BMI was asked only on the Sample Adult Core questionnaire.
Sleep, Working Hours and Risk of Injury 1021 TABLE 2 Top 10 occupations and industries of study subjectsa Number of subjects Weighted Weighted Characteristic interviewed frequency (000s) percent Total 74,415 278,650 100.0 Industry Health Care and Social Assistance 9,641 35,458 13.1 Manufacturing 8,037 29,957 11.1 Retail Trade 7,441 28,255 10.5 Education Services 6,608 25,374 9.4 Construction 5,404 19,914 7.4 Accommodation and Food Services 4,487 16,065 6.0 Professional, Scientific, and Tech Services 4,443 18,177 6.7 Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 Public Administration 3,746 14,214 5.3 Other Services (except Public Administration) 3,662 13,239 4.9 Finance and Insurance 3,496 13,733 5.1 Otherb 14,885 55,366 20.5 Occupation Office and Administrative Support 10,238 38,294 14.2 Sales and Related 7,459 29,004 10.8 Management 6,328 25,286 9.4 Production 5,162 18,180 6.7 Construction and Extraction 4,376 15,572 5.8 For personal use only. Education, Training, and Library 4,303 16,832 6.2 Transportation and Material Moving 4,148 14,987 5.6 Healthcare Practitioners and Technical 3,734 14,606 5.4 Food Preparation and Serving Related 3,685 13,230 4.9 Building and Grounds Cleaning and Maintenance 3,234 10,341 3.8 Otherc 19,192 73,439 27.2 Paid Hourly No 30,595 119,341 42.5 Yes 44,349 161,428 57.5 Missing 552 a Persons aged 18–24 yrs reporting working the previous week, weekly work hours, usual daily and sleep duration. b Other industries include Administrative and Support and Waste Management/Remediation Services; Transportation and Warehousing; Wholesale Trade; Information; Real Estate and Rental/ Leasing; Arts, Entertainment, and Recreation; Agriculture, Forestry, Fishing, and Hunting; Utilities; Mining; Armed Forces; Management of Companies/Enterprises. c Other occupations include Business and Financial Operations; Installation, Maintenance, and Repair; Personal Care and Service; Computer and Mathematical; Healthcare Support; Protective Service; Arts, Design, Entertainment, Sports, and Media; Architecture and Engineering; Community and Social Services; Legal; Life, Physical, and Social Science; Farming, Fishing, and Forestry; Military Specific. Education Services (9.4%), and Construction (7.4%); however, most indus- tries were represented in the NHIS data. The most frequent occupations were Office and Administrative Support (14.2%), Sales and Related (10.8%), Management (9.4%), Production (6.7%), and Construction and Extraction (5.8%). Most injuries were due to overexertion or strenuous movements (24.5%), falls (23.3%), being cut or pierced (15.5%), and being struck by
1022 D. A. Lombardi et al. Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 For personal use only. FIGURE 2 Percent of subjects injured by cause (ICD-9-CM E-codes). object or person (13.0%) (Figure 2). Machinery and transportation injuries accounted for 3.4% and 2.3% of the injuries, respectively. Weekly Working Hours and Injuries Over the 5-yr study period, there were an estimated 3,634,446 work- related injury episodes, among the approximately 130 million estimated workers at risk annually (incidence = 2.80/100 workers) (Table 3a). Unadjusted annualized injury rates generally increased across the seven categories of weekly work hours: 2.03 (≤20 h/wk), 3.01 (20–30 h), 2.45 (31–40 h), 3.45 (40–50 h), 3.71 (50–60 h), and 4.34 (>60 h). Usual Sleep Duration and Injuries The unadjusted estimated annualized injury rates/100 workers gener- ally increased with decreased duration of usual daily sleep (Table 3b): 7.89 (10 h). Thus, the crude (or unadjusted)
Sleep, Working Hours and Risk of Injury 1023 TABLE 3a Estimated annual injury incidence/100 workers by weekly work hours Average Number of Est. number of Hours number workers work-related Est. number Est. annual worked/ of hours interviewed injuries of workers incidence/ week worked 2004–08a annuallyb annually 100 workers Total 40.3 177,576 3,634,446 129,950,376 2.80 ≤20 h 14.9 14,785 229,343 11,286,527 2.03 21–30 h 27.2 13,333 298,900 9,929,180 3.01 31–40 h 39.3 101,442 1,746,467 71,388,048 2.45 41–50 h 47.4 28,396 761,163 22,042,456 3.45 51–60 h 57.9 13,448 387,346 10,433,206 3.71 >60 h 72.1 6,172 211,227 4,870,959 4.34 Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 a Includes individuals reporting employment at a job or business and who had reported weekly work hours. b A work-related injury was reported by 1,178 (0.70%) workers interviewed. TABLE 3b Estimated annual injury incidence/100 workers by usual daily sleep duration Average Number of Est. number of number of workers with work-related Est. number Est. annual Usual hours hours slept sleep hours injuries of workers at incidence/ For personal use only. slept/day (± SE) 2004–2008a annuallyb risk annually 100 workers Total 7.00 ± 0.004 75,271 1,669,142 56,349,239 2.96 ≤4.99 h 3.80 ± 0.010 1,431 83,730 1,061,759 7.89 5–5.99 h 5.00 4,407 172,462 3,310,950 5.21 6–6.99 h 6.00 17,251 469,756 12,988,074 3.62 7–7.99 h 7.00 25,950 448,458 19,774,245 2.27 8–8.99 h 8.00 22,604 413,942 16,571,317 2.50 9–9.99 h 9.00 2,361 39,101 1,759,342 2.22 >10 h 10.50 ± 0.030 1,267 41,694 883,551 4.72 a Includes individuals reporting employment at a job or business and who had been asked and reported usual sleep hours. b A work-related injury was reported by 544 (0.74%) workers interviewed. rate-ratio comparing those sleeping a total of 10 h of usual daily sleep had a marginally elevated OR. The adjusted injury risk OR for a worker
1024 D. A. Lombardi et al. TABLE 4 Multivariate logistic regression model, adjusted∗ odds ratio estimates Standard Est. odds Parameter Estimate error p value ratio Intercept −5.3859 0.4737
Sleep, Working Hours and Risk of Injury 1025 Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 FIGURE 3 Multivariate logistic regression adjusted odds ratio estimates for usual sleep duration. For personal use only. FIGURE 4 Multivariate logistic regression adjusted odds ratio estimates for weekly work hours. further examination (Figure 4) suggests that there is generally a 2-fold risk across work hour categories in comparison to working ≤20 h/wk, except for the 30–40 h/wk category, where the OR = 1.54 or a 54% increase in work-related injury risk is observed. These can also be seen in
1026 D. A. Lombardi et al. Table 3a, in examining the unadjusted annualized injury rates/100 workers across categories of weekly work hours: 2.03 (≤20 h/wk), 3.01 (20–30 h), 2.45 (31–40 h), 3.45 (40–50 h), 3.71 (50–60 h), and 4.34 (>60 h). DISCUSSION This study of the adult population of the USA pooled data across the 5 most recent years of the NHIS survey (2004–2008) and found that both sleep duration and weekly working hours are significantly and independently (i.e., there was no significant interaction between these Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 factors) associated with the risk of a work-related injury. Decreases in usual sleep duration and increases in weekly working hours both increased injury risk, even after controlling for several important socio- demographic, job-related, and physical factors. Thus, reduced sleep increased injury risk, regardless of the number of hours worked/week and, conversely, hours/week worked increased injury risk, regardless of usual daily sleep duration. If the potential impact of these risk factors is considered simultaneously, the independent additive risk of a work- For personal use only. related injury could be substantial. For example, comparing a person working >60 h/wk and a usual daily sleep duration of
Sleep, Working Hours and Risk of Injury 1027 response speed typically being reduced and the frequency of errors and omissions increased when individuals are fatigued (Williamson et al., in press). Strengths and Limitations An important strength of the current study is its strong external val- idity due to the use of pooled NHIS data, which are representative of the adult population of the USA. Pooling of 5 yrs of NHIS data also provided a large sample size, providing strong statistical power to both evaluate our primary hypotheses and to effectively control for several important Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 potential confounders. The use of NHIS data, and the ability to identify each injury for work-relatedness, overcomes many of the shortcomings inherent in other large national data sources (Smith et al., 2006). Our study used a 3-month recall period for self-reported medically treated injuries, which may underreport some injuries (Warner et al., 2005). However, although injury recall improves with increasing severity, it is unlikely to result in differential underestimation of injuries (Harel et al., 1994; Smith et al., 2006). Self-reported sleep duration has been reported For personal use only. in some studies to systematically overestimate more objectively measured sleep time (Lauderdale et al., 2008; Lockley et al., 1999), and daily varia- bility in sleep time makes it difficult to integrate over long periods. In addition, usual sleep patterns may not be representative of the sleep dur- ation or sleep quality at the time of a reported injury; however, we have no information in the current study on the timing of the sleep episode(s), which might be important with respect to injury risk. With respect to weekly work hours, a weekly average may not reflect the highest risk periods for an injury, e.g., time on task, and in the current cross-sectional study, we have no estimate of exposed and nonexposed person’s time to other potential work hazards. Another potentially important limitation of this study is that the NHIS does not include information on the particu- lar work shift of each individual, e.g., permanent night versus rotating shiftworkers; thus, we cannot evaluate whether shiftwork mediates the relationship between sleep duration and injury risk. However, the Sample Adult Core of the NHIS collects individual-level data on industry, occupation, and type of pay, which were controlled for in the logistic regression model. Although imperfect, these work-related variables may provide limited control for shiftwork as a variable, as they are likely correlated with typical worker exposure to shiftwork (e.g., construction workers), however not for the type of work shift. Also, BMI was calculated from self-reported height and weight, there may be some inaccuracy in our measure of body mass. However, it is unlikely that height and weight would be differentially reported by injured and uninjured persons (Breslow & Smothers, 2005).
1028 D. A. Lombardi et al. Conclusions Workplace health and safety can be improved by reducing worker fatigue and risk. In the current study both sleep duration and weekly working hours were independently associated with the risk of a work- related injury. However, when considering the impact of various work schedules on injury risk, it is important to take into account the com- ponents of weekly work hours, such as the length of the individual shifts, the type of shift, breaks, and number of successive shifts worked (Folkard & Lombardi, 2005), and importantly, the opportunity for sufficient sleep duration needed for the adequate rest and recovery of the worker. Chronobiol Int Downloaded from informahealthcare.com by 143.115.159.53 on 07/19/10 ACKNOWLEDGMENTS This work was supported by the Liberty Mutual Research Institute for Safety. The authors are grateful to Dr. Mary F. Lesch and Dr. Yueng- hsiang (Emily) Huang for their thoughtful comments on this manuscript. Declaration of Interest: The authors report no conflicts of interest. For personal use only. The authors alone are responsible for the content and writing of the paper. REFERENCES Åkerstedt T, Knutsson A, Westerholm P, Theorell T, Alfredsson L, Kecklund G. (2002). Sleep disturb- ances, work stress and work hours: a cross-sectional study. J. Psychosom. Res. 53:741–748. Ayas NT, White DP, Manson JE, Stampfer MJ, Speizer FE, Malhotra A, Hu FB. (2003). A prospective study of sleep duration and coronary heart disease in women. Arch. Intern. Med. 163:205–209. Biggi N, Consonni D, Galluzzo V, Sogliani M, Cosat G. (2008). Metabolic syndrome in permanent night workers. Chronobiol. Int. 25:443–454. Binder D. (1983). On the variance of asymptotically normal estimators from complex surveys. Int. Stat. Rev. 51:279–292. Bohle P, Di Milia L, Fletcher A, Rajaratnam S. (2008). Introduction: aging and the multifaceted influ- ences on adaptation to working time. Chronobiol. Int. 25:155–164. Botman SL, Moore TF, Moriarity CL, Parsons VL. (2000). Design and estimation for the National Health Interview Survey, 1995–2004. National Center for Health Statistics. Vital Health Stat. 2. 130:1–31. Breslow RA, Smothers BA. (2005). Drinking patterns and body mass index in never smokers: National Health Interview Survey, 1997–2001. Am. J. Epidemiol. 161:368–376. Caruso CC, Bushnell T, Eggerth D, Heitmann A, Kojola B, Newman K, Rosa R, Sauter SL, Vila B. (2006). Long working hours, safety, and health: toward a National Research Agenda. Am. J. Ind. Med. 49:930–942. Center for Disease Control. (2008). QuickStats: percentage of adults aged >18 years who reported an average of
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