Cluster "Health" WP 2021-2022* - 10 giugno, 2021 Sapienza Università Roma - La Sapienza
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Cluster «Health» WP 2021-2022* cluster1@apre.it Caterina Buonocore 10 giugno, 2021 Sapienza Università Roma * La presentazione recupera ed elabora materiale della EC sul programma Horizon Europe. Link
VERSO IL TRAGUARDO… SIAMO QU Luglio 2018 Aprile 2019 Luglio 2019 Aprile 2020 Novembre 2020 Gennaio 2021 Marzo2021 Maggio 2021 EU Elections New European Commission 26/4 – Voto finale PE Horizon Europe negotiations - 1st phase Horizon Europe negotiations – 2nd phase Horizon Europe (Parliament + Council) (Parliament + Council) APPROVED Commission Proposal Partial Agreement Final Agreement Council approval (June 2018) Consolidated Text (April 2019) (Dec 2020) (16 Mar 2021) Strategic Planning + Missions + Partnerships (Strategic Programme Committee Shadow + others) Open Consultation Strategic Plan Specific missions (June - August 2019) adopted (15 March 2021) proposed 2021-22 W Work Programme Preparation (Thematic Programme Committees Shadow) ADOPTED Start of WP Preparation ERC WP EIC WP (Feb 2020) adopted adopted
Più fonti di finanziamento per le politiche sanitarie Altri programmi dell'UE forniranno ulteriori rescEU investimenti nel settore della salute, FESR Digital complementari a Europe Horizon Europe. FSE+ EU4Health Horizon Europe
Guida alla documentazione: dove trovare cosa Legal texts (Framework Programme & Specific Programme): objectives, structure, budget, R&I activities, rules… Strategic Plan 2021-24: strategic orientations for R&I, missions, partnerships… Work Programmes 2021-22: calls, topics… Proposal templates: RIA, IA, CSA, ERC… Model Grant Agreement Reference documents (European Commission): Funding and Tenders portal Tutti i documenti disponibili su Horizon Europe (APRE): https://horizoneurope.apre.it/documenti-di-riferimento/ NEW! Gli Infodays della CE dal 28 giugno all’8 luglio!: https://www.horizon-europe-infodays2021.eu/ https://www.horizon-europe-infodays2021.eu/event/cluster-1-health Brokerage event per il Cluster 1 : 5 luglio, 2021 https://healthbe2021.b2match.io/
SPECIFIC OBJECTIVES Areas of intervention Cluster Health Improving and protecting the health of Health throughout the life course citizens at all ages, by developing innovative solutions to prevent, diagnose, Non-communicable and rare diseases CLUSTER 1. Health monitor, treat and cure diseases; Tools, technologies and digital mitigating health risks, protecting solutions for health and care, including populations and promoting good health; personalised medicine making public health systems more cost- Environmental and social health effective, equitable and sustainable; and determinants supporting and enabling patients’ Infectious diseases, including poverty- participation and self-management. related and neglected disease Health care systems 6
Cluster Health IL NUOVO GLOSSARIO NEL QUADRO LOGICO • Salute lungo l'arco della vita • Malattie non trasmissibili e rare • Strumenti, tecnologie e soluzioni digitali per la salute e l'assistenza, compresa la medicina personalizzata Base Pillar/Cluster Aree di • Determinanti ambientali e sociali della salute intervento legale • Malattie infettive, comprese le malattie correlate alla povertà e trascurate • Sistemi sanitari Piano Priorità KSO – Orientamenti Impatti attesi politiche EU (impacts) Strategico strategici Piano di Destinazioni Topic Risultati attesi lavoro (outcomes) 7
WORK PROGRAMME “HEALTH” 2021-2022 Relazione con il Piano Strategico 2021-2024 ▪ 2 Key Strategic Orientations ▪ 4 impact areas (Piano Strategico): (Piano Strategico): ▪ Good health and high-quality accessible ▪ Promoting an open strategic healthcare autonomy by leading the ▪ A resilient EU prepared for emerging development of key digital, threats enabling and emerging ▪ High quality digital services for all technologies, sectors and ▪ Competitive and secure data-economy value chains ▪ Creating a more resilient, inclusive and democratic European society
WORK PROGRAMME “HEALTH” 2021-2022 6 Destinations 1. Staying Healthy in a rapid changing society 2. Living and working in a health-promoting environment 3. Tackling diseases and reducing disease burden 4. Ensuring access to innovative, sustainable and high-quality health care 5. Unlocking the full potential of new tools, technologies and digital solutions for a healthy society 6. Maintaining an innovative, sustainable and globally competitive health industry 14/06/2021 9
CLUSTER HEALTH | DESTINATION 1 Staying healthy in a rapidly changing society ▪ Affronta le principali sfide sociali come l'obesità, TOPICS 2021: l'invecchiamento e il cambiamento demografico, ✓ Towards a molecular and neurobiological understanding la salute mentale, l’empowerment nell’ambito of mental health and mental illness for the benefit of della digital health literacy, la prevenzione citizens and patients - RIA personalizzata e l'Intelligenza Artificiale applicata ✓ Healthy Citizens 2.0 - Supporting digital empowerment alle malattie croniche. and health literacy of citizens - CSA ▪ Progetti di ricerca e innovazione che ✓ A roadmap for personalised prevention - CSA forniscano nuove evidenze, metodologie e ✓ Mobilising a network of National Contact Points (NCPs) strumenti per comprendere la transizione for the Health Cluster - CSA dalla salute alla malattia. Scadenza : 21 Settembre 2021 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 1 Staying healthy in a rapidly changing society ▪ Affronta le principali sfide sociali come l'obesità, TOPICS 2022: l'invecchiamento e il cambiamento demografico, ✓ Boosting mental health in Europe in times of change – la salute mentale, l’empowerment nell’ambito RIA della digital health literacy, la prevenzione ✓ Trustworthy artificial intelligence (AI) tools to predict the personalizzata e l'Intelligenza Artificiale applicata risk of chronic non-communicable diseases and/or their alle malattie croniche. progression – RIA ▪ Progetti di ricerca e innovazione che ✓ Prevention of obesity throughout the life course – RIA forniscano nuove evidenze, metodologie e strumenti per comprendere la transizione Scadenza: 1 Febbraio/6 Settembre 2022 – TWO-STAGE dalla salute alla malattia. ✓ Personalised blueprint of chronic inflammation in health- to-disease transition – RIA Scadenza: 21 Aprile 2022 – SINGLE STAGE
DESTINATION 1 | HORIZON-HLTH-2021-STAYHLTH-01-02 ▪ Towards a molecular and ✓ Deeper understanding of (epi)genetics, environmental risks neurobiological understanding and resilience factors EXPECTED OUTCOMES & SCOPE of mental health and mental ✓ Biomarkers discovery illness for the benefit of citizens ✓ Comprehensive clinical trial data on and patients the effectiveness of different (non-) pharmacological prevention strategies Type of Action Research & Innovation Action (RIA) Expected EU About EUR 10.00 million ✓ Prediction of treatment response and risk of relapse contribution per project ✓ Multidisciplinary research, incl. 6 PROGETTI medical sciences, psychological Budget EUR 60.00 million sciences & social sciences and Deadline 21 Settembre 2021 – SINGLE STAGE humanities
CLUSTER HEALTH | DESTINATION 2 Living and working in a health-promoting environment* ▪ Comprendere gli impatti dell'inquinamento atmosferico TOPICS 2021: indoor/outdoor, delle sostanze chimiche, dei campi ✓ Exposure to electromagnetic fields (EMF) and health - RIA elettromagnetici, dell'urbanizzazione, del cambiamento ✓ Indoor air quality and health – RIA climatico e di altri cambiamenti ambientali, delle ✓ Health impacts of climate change costs and benefits of disuguaglianze socioeconomiche e del cambiamento degli action and inaction – RIA ambienti di lavoro. ✓ European partnership for the assessment of risks from ▪ Rafforzare la capacità di adattamento e la resilienza delle chemicals (PARC) - Programme Co-fund Action popolazioni e dei sistemi sanitari rispetto ai rischi per la salute legati ai cambiamenti climatici e ambientali. Scadenza : 21 Settembre 2021 – SINGLE STAGE * Forte connessione con European Green Deal
CLUSTER HEALTH | DESTINATION 2 Living and working in a health-promoting environment* ▪ Comprendere gli impatti dell'inquinamento atmosferico TOPICS 2022: indoor/outdoor, delle sostanze chimiche, dei campi ✓ Methods for assessing health-related costs of elettromagnetici, dell'urbanizzazione, del cambiamento environmental stressors – RIA climatico e di altri cambiamenti ambientali, delle disuguaglianze socioeconomiche e del cambiamento degli ambienti di lavoro. Scadenza : 21 Aprile 2022 – SINGLE STAGE ▪ Rafforzare la capacità di adattamento e la resilienza delle popolazioni e dei sistemi sanitari rispetto ai rischi per la salute legati ai cambiamenti climatici e ambientali. * Forte connessione con European Green Deal
DESTINATION 2 | HORIZON-HLTH-2021-ENVHLTH-02-02 ▪ Indoor air quality and health ✓ FAIR data on air pollutants determinants, sources and risk factors EXPECTED OUTCOMES & SCOPE ✓ User-friendly solutions to monitor indoor air quality ✓ Proposals for revised indoor air quality standards Type of Action Research & Innovation Action (RIA) ✓ Identification of sources and routes Expected EU About EUR 8 million of exposure and dispersion of chemical and biological indoor air contribution pollution per project 5 PROGETTI ✓ Development of scalable Budget EUR 40.00 million technologies to improve indoor air Deadline 21 Settembre 2021 – SINGLE STAGE quality and reduce disease burdens
CLUSTER HEALTH | DESTINATION 3 Tackling diseases TOPICS 2021: and reducing ✓ Improved supportive, palliative, survivorship and end-of- disease burden* life care of cancer patients - RIA ✓ Building a European innovation platform for the ▪ Si concentra sulle principali sfide sociali come il cancro, le repurposing of medicinal products – RIA malattie non trasmissibili, le malattie rare, la resistenza ✓ Innovative approaches to enhance poverty-related antimicrobica, la vaccinazione e la preparazione alle diseases research in sub-Saharan Africa - RIA epidemie. ✓ Clinical validation of AI solutions for treatment and care – ▪ Sviluppo di nuove misure di prevenzione, terapie e RIA tecnologie sanitarie innovative. ✓ Personalised medicine and infectious diseases: understanding the individual host response to viruses (e.g. SARS-CoV-2) – RIA ✓ A roadmap towards the creation of the European partnership on One Health antimicrobial resistance (OH * Complementare a Europe’s Beating Cancer AMR) – CSA Plan e EU4Health Programme ✓ Building a European partnership for pandemic preparedness - CSA Scadenza : 21 Settembre 2021 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 3 Tackling diseases TOPICS 2022: and reducing ✓ Pre-clinical development of the next generation of disease burden* immunotherapies for diseases or disorders with unmet medical needs - RIA ▪ Si concentra sulle principali sfide sociali come il cancro, le ✓ Vaccines 2.0 - developing the next generation of vaccines – malattie non trasmissibili, le malattie rare, la resistenza RIA ✓ Development of new effective therapies for rare diseases – antimicrobica, la vaccinazione e la preparazione alle RIA epidemie. ▪ Sviluppo di nuove misure di prevenzione, terapie e Scadenza: 1 Febbraio/6 Settembre 2022 – TWO-STAGE tecnologie sanitarie innovative. ✓ Pandemic preparedness - RIA ✓ Non-communicable diseases risk reduction in adolescence and youth (Global Alliance for Chronic Diseases - GACD) - RIA ✓ Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) * Complementare a Europe’s Beating Cancer – CSA Plan e EU4Health Programme ✓ European partnership fostering a European Research Area (ERA) for health research – Placeholder – Programme Co-fund Action Scadenza: 21 Aprile 2022 – SINGLE STAGE
DESTINATION 3 | HORIZON-HLTH-2021-DISEASE-04-04 ▪ Clinical validation of artificial ✓ Evidence-based clinical decision support for affordable treatment, intelligence solutions for including home-based care EXPECTED OUTCOMES & SCOPE treatment and care ✓ Clinical development, testing and validation of AI-driven treatment and care options ✓ Measure the (cost-)effectiveness of AI- driven development of therapeutic Type of Action Research & Innovation Action (RIA) concepts Expected EU About EUR 6 million ✓ Healthcare professionals better predict contribution patients’ response to personalised treatment per project 10 PROGETTI ✓ Focus on traceability, transparency and Budget EUR 60.00 million auditability of AI algorithms in health Deadline 21 Settembre 2021 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 4 Ensuring access to innovative, sustainable and high-quality care* ▪ Sviluppo e adozione di soluzioni sicure, convenienti e TOPICS 2021: incentrate sulle persone, con particolare attenzione alla ✓ Enhancing quality of care and patient safety - RIA salute della popolazione, alla resilienza dei sistemi sanitari ✓ Data-driven decision-support tools for better health care e alle politiche sanitarie basate sull'evidenza scientifica. delivery and policy-making with a focus on cancer – RIA ▪ R&I per supportare i sistemi sanitari nella loro ✓ Health care innovation procurement network - CSA trasformazione per garantire un accesso equo a Scadenza : 21 Settembre 2021 – SINGLE STAGE servizi sanitari sostenibili di alta qualità per tutti i cittadini. * Forte sinergia con EU4Health Programme
CLUSTER HEALTH | DESTINATION 4 Ensuring access to innovative, sustainable and high-quality care* TOPICS 2022: ✓ Pre-commercial research and innovation procurement ▪ Sviluppo e adozione di soluzioni sicure, convenienti e (PCP) for building the resilience of health care systems in incentrate sulle persone, con particolare attenzione alla the context of recovery - PCP salute della popolazione, alla resilienza dei sistemi sanitari ✓ Public procurement of innovative solutions (PPI) for e alle politiche sanitarie basate sull'evidenza scientifica. building the resilience of health care systems in the ▪ R&I per supportare i sistemi sanitari nella loro context of recovery – PPI trasformazione per garantire un accesso equo a ✓ Better financing models for health systems – RIA servizi sanitari sostenibili di alta qualità per tutti i ✓ European partnership on transforming health and care cittadini. systems – Programme Co-fund Action Scadenza : 21 Aprile 2022– SINGLE STAGE * Forte sinergia con EU4Health Programme
DESTINATION 4 | HORIZON-HLTH-2021-CARE-05-01 ▪ Enhancing quality of care and ✓ Develop and implement coherent quality improvement and patient patient safety safety strategies EXPECTED OUTCOMES & SCOPE ✓ Harmonisation and standardisation of health care processes ✓ Fill knowledge and practice gaps Type of Action Research & Innovation Action (RIA) in quality of care and patient Expected EU About EUR 5 million safety contribution ✓ Innovative approaches for per project 5 PROGETTI personalised treatment plans Budget EUR 25.00 million ✓ Empower and involve patients Deadline 21 Settembre 2021 – SINGLE STAGE and caregivers
CLUSTER HEALTH | DESTINATION 5 Unlocking the full potential of new tools, technologies and digital solutions for a healthy society* TOPICS 2021: ▪ Promuovere lo sviluppo di strumenti, tecnologie e ✓ Smart medical devices and their surgical implantation for soluzioni digitali per trattamenti, farmaci, dispositivi use in resource-constrained settings - IA medici, tenendo in considerazione sicurezza, efficacia, ✓ Next generation advanced therapies to treat highly adeguatezza, accessibilità e valore aggiunto. prevalent and high burden diseases with unmet medical ▪ I dati sanitari e gli strumenti analitici innovativi needs – RIA vengono utilizzati in modo sicuro ed etico. ✓ Innovative tools for use and re-use of health data (in particular of electronic health records and/or patient registries) - RIA * [!] European Health Data Space per promuovere lo Scadenza : 21 Settembre 2021 – SINGLE STAGE scambio di dati sanitari e la ricerca transfrontaliera.
CLUSTER HEALTH | DESTINATION 5 Unlocking the full potential of new tools, technologies and digital solutions for a healthy TOPICS 2022: ✓ Optimising effectiveness in patients of existing society* prescription drugs for major diseases (except cancer) ▪ Promuovere lo sviluppo di strumenti, tecnologie e with the use of biomarkers - RIA soluzioni digitali per trattamenti, farmaci, dispositivi ✓ New methods for the effective use of real-world data medici, tenendo in considerazione sicurezza, efficacia, and/or synthetic data in regulatory decision-making adeguatezza, accessibilità e valore aggiunto. and/or in health technology assessment – RIA ▪ I dati sanitari e gli strumenti analitici innovativi Scadenza : 21 Aprile 2022– SINGLE STAGE vengono utilizzati in modo sicuro ed etico. ✓ Computational models for new patient stratification strategies - RIA * [!] European Health Data Space per promuovere lo Scadenza: 1 Febbraio/6 Settembre 2022 – TWO-STAGE scambio di dati sanitari e la ricerca transfrontaliera.
DESTINATION 4 | HORIZON-HLTH-2021-TOOL-06-02 ▪ Next generation advanced ✓ Test new advanced therapies based on pluripotent stem cells, gene therapies to treat highly editing or RNA through clinical trials EXPECTED OUTCOMES & SCOPE prevalent and high burden meeting the appropriate regulatory requirements diseases with unmet medical ✓ Method development for needs production and differentiation of pluripotent stem cells Type of Action Research & Innovation Action (RIA) ✓ Development/validation of Expected EU About EUR 6 million ✓ Biological assays & methods that contribution demonstrate efficacy, delivery, per project specificity and safety of genome editing 10 PROGETTI products in targeted cells and tissues Budget EUR 60.00 million ✓ novel RNA-based therapies for non- communicable diseases Deadline 21 Settembre 2021 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 6 Maintaining an innovative, sustainable and globally competitive health industry* ▪ Adozione di tecnologie e innovazioni rivoluzionarie TOPICS 2021: in grado di integrare gli attori della catena del ✓ Green pharmaceuticals - RIA valore. ✓ Development, procurement and responsible management of new antimicrobials – CSA ▪ L'industria sanitaria dell'UE è più competitiva, ✓ Promoting a trusted mHealth label in Europe: uptake of sostenibile e strategicamente autonoma. technical specifications for quality and reliability of health and wellness apps - CSA Scadenza : 21 Settembre 2021 – SINGLE STAGE
CLUSTER HEALTH | DESTINATION 6 Maintaining an innovative, sustainable and globally competitive health industry* ▪ Adozione di tecnologie e innovazioni rivoluzionarie TOPICS 2022: in grado di integrare gli attori della catena del ✓ Enhancing cybersecurity of connected medical devices - valore. RIA ✓ Scaling up multi-party computation, data anonymisation ▪ L'industria sanitaria dell'UE è più competitiva, techniques, and synthetic data generation – RIA sostenibile e strategicamente autonoma. ✓ New pricing and payment models for cost-effective and affordable health innovations – RIA ✓ Setting up a European Smart Health Innovation Hub – CSA ✓ Setting up a European Electronic Health Record Exchange Format (EEHRxF) Ecosystem - CSA Scadenza : 21 Aprile 2022 – SINGLE STAGE
DESTINATION 4 | HORIZON-HLTH-2021-IND-07-03 ▪ Promoting a trusted mHealth ✓ European mHealth label allows more rapid integration of trusted solutions label in Europe: uptake of ✓ EXPECTED OUTCOMES & SCOPE Propose activities that bring together technical specifications for app developers, health and care system representatives, medical societies, quality and reliability of health patient organisations, certification and wellness apps bodies etc. ✓ Set up a structured dialogue on the Type of Action Research & Innovation Action (RIA) uptake of the Technical Specifications Expected EU About EUR 2 million ✓ Co-create, develop and implement an contribution action plan on the promotion of the mHealth label in the health and care per project 1 PROGETTO system Budget EUR 2 million ✓ Inclusive dissemination strategy Deadline 21 Settembre 2021 – SINGLE STAGE
✓ Centra lo Scope del topic TIPS & TRICKS ✓ Attenzione ai criteri di eleggibilità ✓ Excellence: novità e chiarezza degli obiettivi ✓ Impact: ✓ Affrontare tutti gli impatti previsti/richiesti in modo credibile e quantificabile ✓ Affrontare gli impatti di tipo economico e sociale con termini e numeri appropriati ✓ Prevedere misure per disseminare e sfruttare i risultati ✓ Implementation: la proposta è chiara, logica, di facile lettura, credibile e convincente ✓ Consorzio: il partenariato copre tutte le competenze richieste, ha l’esperienza e l’expertise necessarie.
OLTRE IL CLUSTER 1 «Health» Opportunità per il settore Salute nell’ambito degli altri Cluster del Pillar 2
CLUSTER 2. Culture, creativity and inclusive society Democrazia e governance ▪ obiettivo di creare sistemi di governance democratica sostenibili in un mondo post- pandemico Strengthening European democratic Trasformazioni sociali ed economiche values, including rule of law and ▪ La dimensione sanitaria gioca inevitabilmente fundamental rights, safeguarding un ruolo importante nei bandi che affrontano our cultural heritage, and le condizioni dei migranti e dei rifugiati in Europa promoting socio-economic Futuro sostenibile per l’Europa transformations that contribute to ▪ Inclusività del mercato del lavoro in termini di inclusion and growth, disabilità, salute, età e invecchiamento
CLUSTER 4. Digital, Industry and Space Tecnologie produttive Materiali avanzati Internet di prossima generazione Industrie circolari Reinforcing capacities and securing Spazio, compresa l'osservazione della terra Europe’s sovereignty in key enabling Tecnologie abilitanti emergenti Tecnologie digitali fondamentali, comprese le tecnologie technologies for digitization and quantistiche production, and in space technology, Intelligenza artificiale e robotica to build a competitive, digital, low- Calcolo avanzato e Big Data Industria a basse emissioni di CO2 e pulita carbon and circular industry; ensure Tecnologie abilitanti emergenti a sustainable supply of raw ▪ DESTINATION 2 – INCREASED AUTONOMY IN KEY STRATEGIC materials; and provide the basis for VALUE CHAINS FOR RESILIENT INDUSTRY > Biomaterials database for Health Applications advances and innovation in all global ▪ DESTINATION 4 – DIGITAL AND EMERGING TECHNOLOGIES societal challenges. FOR COMPETITIVENESS AND FIT FOR THE GREEN DEAL > Quantum sensing technologies for market uptake
CLUSTER 6. Food, bioeconomy, natural resources, agriculture and environment Osservazione ambientale Agricoltura, silvicoltura e zone rurali Protecting, restoring, sustainably Sistemi circolari managing and using natural and Sistemi alimentari biological resources from land and Biodiversità e risorse naturali sea to address food and nutrition Mari, oceani e acque interne security and the transition to a low Sistemi di innovazione biologici nell'UE carbon, resource efficient circular Bioeconomia economy.
CLUSTER 6 – Destination 2 – Fair, healthy and environmentally- friendly food systems from primary production to consumption ✓ Improved understanding of the factors influencing dietary ▪ From farming to food systems behaviour of different target groups EXPECTED OUTCOMES & SCOPE ▪ Expected topics for 2021: > Means to foster behavioural ▪ Vaccines and diagnostics for priority changes animal diseases ✓ A scientific basis to support policy ▪ Assessment of alternative proteins and makers and Member States for dietary shift notably in nutritional and dietary advice and communication allergy terms ▪ Microbes for healthy and sustainable strategies food and diets ✓ Ultimate objective to empower ▪ [RIA] Transition to healthy and citizens to make informed food sustainable dietary behaviour choices ▪ One health approach for Food Nutrition Security and Sustainable Agriculture ✓ Link with topics on prevention of (FNSSA) obesity
CLUSTER 6 – Destination 6 – Resilient, inclusive, healthy and green rural, coastal and urban communities ✓ Addressing the issue of poorly planned urban food environments ▪ Focus here on the communities rather that drive citizens, and children in EXPECTED OUTCOMES & SCOPE than on the value chain particular, towards unhealthy packaged food that is high in ▪ Drive community-led innovations with calories, sugar, salt and saturated through social and behavioural fat, which contributes to obesity and diet-related illnesses sciences dimension ✓ Driving people towards health food ▪ Inclusion and governance key choices and transforming urban food systems to be healthier ▪ Expected topics for 2021: ✓ Governance and multi-actors ▪ [IA] Integrated urban food system engagement including from higher policies – how cities and towns can education institutions and research transform food systems for co-benefits centres
PILLAR 2 | TIMELINE ALTRI CLUSTER Pubblicazione WP: giugno 2021 Scadenze call: settembre ottobre 2021 Call 2021: single stage Call 2022: single + two-stage
OLTRE IL PILLAR 2 Opportunità per il settore Salute nell’ambito degli altri Pillar
OLTRE IL PILLAR 2 | PILLAR 3 Stimolare innovazioni pionieristiche creatrici di mercato ed ecosistemi favorevoli all'innovazione Consiglio Ecosistemi Istituto europeo europeo per europei per di innovazione e l'innovazione l'innovazione tecnologia (EIT) ▪ Sostegno alle ▪ Instaurare un ▪ Riunire gli operatori innovazioni dal legame con gli fondamentali (ricerca, potenziale operatori istruzione e imprese) pionieristico e dell'innovazione a attorno a un obiettivo creatrici di mercato livello regionale e comune per favorire nazionale l'innovazione Proposta della Commissione: 10,5 miliardi Proposta della di EUR, compresi fino a 500 milioni di EUR Commissione: per gli ecosistemi 3 miliardi di EUR 37
OLTRE IL PILLAR 2 | PILLAR 3: EIC Supporto all'intero ciclo di innovazione, dalla ricerca e sviluppo allo scale up di tecnologie e imprese innovative (principalmente start-up e PMI) a livello internazionale. • Pathfinder(ex-FET):early-stage researchof breakthrough technologies by a multidisciplinaryconsortium • Transition:developmarket readinessof most potential researchfindings – openonly to Pathfinderor ERC Pathfinder PoCprojects • Accelerator(exSMEInstrument): finalizethe technology, commercialisationand scale-upby single innovativeSMEs Transition ▪ Prevalentemente BOTTOM UP Open Calls ▪ Tutti gli strumenti EIC in APRE: contribuiscono anche alle eic@apre.it priorità tematiche: Health & Accelerator Biotech, Digital,Energy,Climate & Environment: ChallengeCalls
OPPORTUNITA’ PER IL SETTORE SALUTE IN EIC PATHFINDER TRANSITION ACCELERATOR TRL 1-4 4 – 5/6 5/6 - 9 Single applicant Single Start-ups & SMEs (incl. spin-out), CHI PUÒ > 3 partner in > 3 Stati Membri Piccoli consorzi (< 5 partner) Individuals (intending to launch an SME) PARTECIPARE Single applicant (in alcuni casi) Small midcaps (equity-only) Solo basati su ERC PoC & Pathfinder BLENDED FINANCE < 2.5 €m grant for tech devpt. / valid. < 2.5 €m < € 3m 0.5 - 15 €m investment component for scaling up / other Validate & demonstrate tech in COSA Achieve proof of principle & validate application-relevant environment & activities. FINANZIA scientific basis of breakthrough tech Grant only/grant first is possible develop market readiness Investment only for small mid-caps or as follow up to grant only + 2 Challenge-based topics: + 1 Challenge-based topic: + 1 Challenge-based topics: ▪ Tools to measure and stimulate activity in ▪ Medical Technology and Devices: ▪ Strategic Digital and Health Technologies (AI-driven brain tissue from Lab to Patient tools for early diagnostics, point-of-care, bioprocessing 4.0, ▪ Emerging Technologies in Cell and Gene healthcare intelligence services, e-health solutions) therapy 2 cut-off dates: 19 May (open call) 22 September 9 June 27 October (challenge call) 6 October
EU MISSIONS Legate ad uno o più cluster del Pillar 2 40
EU MISSIONS Adaptation to climate change, including societal Cluster 5, Cluster 2 Legate ad uno o più transformation cluster del Pillar 2 Healthy oceans, Cluster 6 seas, Cluster 1 coastal Mission Cancer and inland waters areas Climate-neutral Soil health Cluster 5 and food Cluster 6 and smart cities 41
MISSIN CANCER | News Conquering Cancer: Mission Possible 13 recommendations Targets by 2030: more than 3 million lives saved, living longer and better: achieve a thorough understanding of cancer, prevent what is preventable, optimise diagnosis and treatment, support the quality of life of all people exposed to cancer, and ensure equitable access to the above across Europe. Aggiornato la pagina delle Mission sul sito della Commissione: https://ec.europa.eu/info/horizon-europe/missions-horizon- europe_en ▪ Nomine dei mission managers e dei vice: https://ec.europa.eu/info/horizon-europe/missions-horizon-europe_en ▪ Schede per la valutazione dei piani d’implementazione, che dovrebbero essere presentati a giugno: https://ec.europa.eu/info/horizon- europe/missions-horizon-europe/assessment-criteria_en
13 raccomandazioni Comprensione Prevenzione Diagnosi e trattamento Qualità di vita Accesso equo Azioni trasversali 1 Varare UNCAN.eu – un'iniziativa europea per comprendere il cancro 2 Sviluppare un programma di ricerca a livello dell'UE per individuare i punteggi di rischio (poli)genico 3 Sostenere lo sviluppo e l'attuazione di strategie e politiche efficaci per la prevenzione del cancro negli Stati membri e nell'UE 4 Ottimizzare i programmi di screening esistenti e sviluppare approcci innovativi per lo screening e la diagnosi precoce 5 Promuovere e attuare approcci di medicina personalizzata per tutti i pazienti oncologici in Europa 6 Sviluppare un programma di ricerca a livello dell'UE per tecnologie di diagnosi precoce e di trattamento mini invasivo Sviluppare un sostegno alle politiche e ai programmi di ricerca a livello dell'UE per migliorare la qualità della vita dei pazienti oncologici e dei 7 sopravviventi, dei familiari e dei prestatori di assistenza, nonché di tutte le persone che presentano una maggiore predisposizione al cancro Creare un centro digitale europeo per i pazienti oncologici in cui questi ultimi e i sopravviventi possano depositare e condividere i loro dati per 8 un'assistenza personalizzata 9 Conseguire l'equità della salute oncologica nell'UE lungo il decorso della malattia Istituire una rete completa di infrastrutture oncologiche all'interno degli Stati membri dell'UE e tra essi al fine di aumentare la qualità della ricerca e 10 dell'assistenza 11 Tumori infantili e tumori in adolescenti e giovani adulti: curare di più e curare meglio 12 Accelerare l'innovazione e l'attuazione di nuove tecnologie e creare laboratori viventi incentrati sull'oncologia per sconfiggere il cancro Trasformare la cultura, la comunicazione e lo sviluppo di capacità 13 in ambito oncologico
MISSI0N CANCER | News Europe-wide platform building on current researches & innovations Investing in new models and technologies interrogating the interactions of cancer and their host as a first approach Integration with longitudinal patient data, samples and biomarkers for identification and translation to patient benefits.
EU PARTNERSHIP | UN NUOVO APPROCCIO Una nuova generazione di partenariati più ambiziosi a sostegno degli obiettivi politici dell'UE ▪ Architettura semplificata Caratteristiche ▪ Approccio strutturato e trasparente all’intero principali ciclo di vita del partenariato ▪ Orientamento strategico Co-funded Co-programmed Institutionalised Sulla base di un Basati su protocolli programma Basati su una visione d'intesa / accordi congiunto concordato a lungo termine e sulla contrattuali; attuati in dai partner; impegno necessità di un'elevata modo indipendente dei partner con integrazione; dai partner e dalla contributi finanziari e partenariati basati su Commissione via in natura e contributo Art.185 /187 del TFUE Horizon Europe finanziario da e sul regolamento EIT Horizon Europe 4 5
EU PARTNERSHIP | A COSA SERVONO ▪ Strumento usato per delegare una parte dell’implementazione del Programma quadro. ✓ Contribuire al raggiungimento delle priorità politiche dell'UE ✓ Allineare priorità settoriali al livello Europeo RAFFORZARE LO ✓ Superare la frammentazione nel panorama della R&I ed SPAZIO EUROPEA evitare la duplicazione degli sforzi DELLA RICERCA ✓ Raggiungere una massa critica di investimenti (importante in HE) ✓ Creare dei network europei (autosufficienti sul lungo termine)
EU PARTNERSHIP | SALUTE ▪ Institutionalised Partnerships: ▪ Innovative Health Initiative (2021) (ex-IMI2) ▪ European Partnership for EU-Africa Global Health (2021) (ex- Draft proposals of the EDCTP2) candidates for ▪ Co-funded Partnerships: European Partnerships in Health: ▪ European Partnership for the Assessment of Risks from Chemicals (PARC) (2021) https://ec.europa.eu/in ▪ European Partnership Fostering an ERA for Health research fo/horizon- (2022) europe/european- ▪ European Partnership on Transforming Health and Care Systems partnerships-horizon- (2022) europe/candidates- ▪ European Partnership for Personalised Medicine (2023) european-partnerships- health_en ▪ European Partnership on Rare Diseases (2024) ▪ European Partnership for One Health/AMR Antimicrobial Resistance (AMR) (2024/25)
Email: cluster1@apre.it Tel. +39 06 48 93 9993 www.apre.it
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