Center for Global Health Equity Inaugural Impact Report 2022 - Interdisciplinary Solutions to Advance Global Health
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Center for Global Health Equity Inaugural Impact Report 2022 Interdisciplinary Solutions to Advance Global Health
Inaugural Impact Report | 2022 University of Michigan Center for Global Health Equity staff Director Joseph C. Kolars Senior Advisor John Z. Ayanian Managing Director Amy Conger Administrative Specialist Kelly Espinoza Finance Lead Parina Kamdar 5 44 39 Communications Manager Josh Messner Administrative Advisor Tania Piotrowski Project Manager Kristina Rice Contents Education & Outreach Alana Rodriguez Program Manager Center History 2 Project Manager Christabel Sefa Investing for Impact faculty leadership team The Impact Scholars Program 4 Omolade Adunbi, Stomach Bugs, Diarrhea, and Other Paths 6 College of Literature, Science, and the Arts to Global Health Work Sue Anne Bell, School of Nursing To Be a Good Steward: Strengthening Systems 9 Matthew L. Boulton, for Healthier Women and Communities School of Public Health Learning the Many Languages of Global Public Health 12 Paul Clyde, William Davidson Institute Data Science and Emerging Tech for Earlier Interventions 15 Joseph Eisenberg, School of Public Health Advancing Healthy Aging in Africa 17 Mary Gallagher, College of Literature, Science, and the Arts Contextualized Engineering Design for Better Health 20 Gary Harper, School of Public Health Advancing Governance and Citizenship 26 Cheryl Moyer, Michigan Medicine in the Ugandan Health Sector Amy Pienta, Institute for Social Research Innovative Approaches to Global Vaccine Equity 30 Lee Schroeder, Michigan Medicine Building Community Akbar Waljee, Michigan Medicine Events that Build Community 33 © 2023 Regents of the University of Michigan Engaging Students 37 The Regents of the University of Michigan Jordan B. Acker, Michael J. Behm, Mark J. Bernstein, Journeys in Global Health Equity 37 Paul W. Brown, Sarah Hubbard, Denise Ilitch, Ron Weiser, Katherine E. White, Mary Sue Coleman (ex officio). Equitable Partnerships Nondiscrimination Policy Statement The University of Michigan, as an equal opportunity/affir- On Campus with Lukoye Atwoli 38 mative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative Top Tweets 41 action. The University of Michigan is committed to a policy of equal opportunity for all persons and does not discrimi- How We Approach Impact 42 nate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender Committed to Changing the World: 44 expression, disability, religion, height, weight, or veteran The Global Legacy of Tachi Yamada status in employment, educational programs and activities, and admissions. Inquiries or complaints may be addressed to the Senior Director for Institutional Equity, and Title IX/Section 504/ADA Coordinator, Office for Institutional Equity, 2072 Administrative Services Building, Ann Arbor, Michigan 48109-1432, 734-763-0235, TTY 734-647-1388, Cover: Center member Jody Lori—professor of Health Behavior and Biological institutional.equity@umich.edu. For other University of Sciences in the U-M School of Nursing—learns about community health visits Michigan information call 734-764-1817 for expectant mothers in Butaro, Rwanda.
A Global Movement to Advance Equity in Health Can you imagine a world where health is not an obstacle to education, employment, and the pursuit of a fulfilling life? At the Center for Global Health Equity, we can envision such a world. And with our many partners around the globe, we are pursuing novel, interdisciplinary solutions to some of our most daunting health equity challenges. What’s different about Michigan’s approach to global health? Our founding donor, the late Tachi Yamada, was so passionate about health equity that our Center is one of the few to include equity in its name. We are motivated by a conviction that, while our health is greatly influenced by the circumstances into which we were born, these barriers can be overcome. While the Center opened its doors during the pandemic, and we mourn the loss of Tachi, we are now operating at full speed to fulfill our charge. As you read about our early successes in this inaugural Impact Report, we hope you will appreciate some unique elements of the Center. We partner differently. Our partners in low- and middle-income countries define our partnerships and projects. They identify the most critical needs in health equity for their communities and develop the research questions that guide our shared work. We are committed to sharing resources and ensuring that our partners benefit from Center funding and enabling structures. We have members around the world, and they confirm with us that our approach to global health collaboration is different. We support a movement. We prioritize and invest in projects that advance the global health equity movement in every way possible. Our work strengthens systems to improve health and health equity, informs public policy, creates new technical solutions for community health, and empowers women as health leaders in their communities. We know there are ways to solve the seemingly intractable Joseph C. Kolars, MD, MACP problems that plague global health, and we are committed to finding them. Director, Center for Global We maximize our resources. We are doing all of this while based at the University Health Equity of Michigan, the leading public research university in the US. By leveraging Senior Associate Dean and Professor of Medicine the unique strengths of this excellent institution, we reach across disciplines to create solutions. In addition to supporting innovative research, we have launched Josiah Macy Jr. Professor of Health Professions Education educational opportunities for our students and extended training and capacity University of Michigan sharing pathways for global partners. These efforts are changing the way we do global health work. This is a big part of the movement—changing the model itself. We are dreaming big. Because this is our inaugural impact report, we have included an overview of the Center’s history (see page 2). We are proud of the foundation we have built and are preparing to take some big next steps. We engage more faculty and global partners every month. Our research models are constantly evaluated and improved so that our partnerships set the standard for collaboration and co-design. We have already deployed a series of seed grants that have led to much larger national and international grants, many of which include global research partners as lead investigators. And we are developing new models for student engagement to prepare future generations of researchers to be leaders in the global health equity movement. Amy Conger, PhD When we are successful, people in the communities we engage will live longer, Managing Director, Center healthier lives. for Global Health Equity Faculty Associate, Center Thank you for supporting the movement. for the Study of Higher and Postsecondary Education University of Michigan
Collaborating across campus and 2016 Exploratory conversations begin between Tachi Yamada and Joe Kolars about a new U-M Center for Global Health Equity. 2017 Tachi Yamada meets with U-M leadership to discuss a catalytic gift to initiate a Tachi Yamada in India. Center for Global Health Equity. 2019 June. Joseph Kolars and John Ayanian convene meetings with diverse stakeholders across three U-M campuses exploring the idea of a new Center for Global Health Equity. October. University of Michigan publicly announces $10 million gift from Tachi and Leslie Yamada in support of global health equity. John Ayanian, Tachi Yamada, Leslie Yamada, and Joseph Kolars in 2019. 2020 September. Center opens with offices on U-M North Campus. Interdisciplinary Challenge Groups convene with emphasis on four thematic areas. Provost Carl Amrhein of Aga Khan University and Center director Joseph Kolars holding signed copies of October. Partnership launched with Aga a memorandum of understanding. Khan University. December. Center reaches 150 members. 2 Global Health Equity at the University of Michigan
around the world to improve health 2021 March. Center launches pilot funding program for Challenge Group Grants to advance high-impact projects. August. Passing of Tachi Yamada, the Center’s founding donor. September. Impact Scholars program launched. Ryan Rego, Victor Rateng, Leon Espira, and Purity Muthoni with Lukoye Atwoli—dean of the Aga Khan University October. $6.5M NIH grant for the Medical College, East Africa—on U-M campus. UZIMA-DS (data science) project with partners at Aga Khan University in Kenya. $6.5M NIH grant for the Heat and Health African Transdisciplinary Center (HE2AT) 2022 project with partners at Aga Khan University in Kenya, IBM Research Africa, February. Global Vaccine Equity Ideas Lab the University of Cape Town, and the convened on Ann Arbor campus. Center University Peleforo Gon Coulibalu. delegation visits partner sites in Uganda and Kenya. March. $338K NIH grant for Longitudinal Study of Health and Aging in Kenya (LOSHAK) with partners at Aga Khan University in Kenya. April. Center reaches 250 members. CGHE Community Gathering, the Center’s first in-person event. May. $440K NSF grant for Characterizing the Use of Contextual Factors during Engineering Design project. The Empowering Women and Communities Challenge September. Seed Grant and Impact Group meets on north campus to discuss recent project work and new collaborations. Accelerator Grant programs launched. November. Center delegation visits partner sites in Rwanda. Collaboration launched with Rwandan Ministry of Health. Center co-hosts Ghana-UM Conference for Global Health Collaboration in Accra. Impact Report 2022 3
Investing for Impact Our version of a postdoc program is different. “Being an Impact Scholar with the Center allows me to dream about “My time with the Center has turned everything on its head, creative interventions and have the helping me understand more support to turn those possibilities fully how my research can into realities that improve the change human lives. ” health of communities. ” —Leon Espira, PhD —HaEun Lee, PhD Espira in Kakamega, Kenya, with his father, Abraham Lee with community research leaders Angella Tushabe Espira, founder and director of Kakamega’s Nala and Christian Atuhaire preparing to facilitate focus group Community Hospital, a key provider of obstetric and discussions in the Bushenyi region of Uganda. gynecological services in Kakamega County. 4 Global Health Equity at the University of Michigan
The Impact Scholars Program The Impact Scholars program prepares exceptional in academia, government, civil society, early-career scholars for work in global health or advocacy as effective, influential leaders. research and program development, with a focus on Working with University of Michigan faculty measurable impact in low-resource settings. mentors, scholars engage in projects that involve Impact Scholars build coherent bodies of their own interdisciplinary collaboration across two or more work and prepare for successful global health careers themes that have been prioritized by the Center. “What makes this program truly unique is how it encourages us to conduct research that pursues impact and to focus on independent scholarship rather than following traditional approaches to research and scholarly publishing. —Ryan Rego, PhD ” Rego at Leda, Camp 24, Cox’s Bazar Refugee camp in Bangladesh with research partners—Sirajul Islam, Ashok Barman, and Kabir Ahmed—conducting meetings with community leaders to refine their survey on vaccination decision making. Impact Report 2022 5
Rego at the Diarrhea Treatment Centre in the Leda refugee camp in the Cox’s Bazar camp complex, Bangladesh. Stomach Bugs, Diarrhea, and Other Paths to Global Health Work When Ryan Rego visited family in Pakistan as a child, As an undergraduate at Case Western Reserve University, I majored in economics and became very he wondered why he had to be so careful about interested in development economics. I also wanted what he ate and drank. This unpleasant but effective to attend medical school to become an emergency introduction to health inequity led Rego to study room physician—the fast pace and broad knowledge gastric conditions and diseases. required resonated with me like nothing else. While at Case Western, I shadowed Justin Yax, an emergency medicine physician who As a child, I could never understand why in Pakistan was also director of the Emergency Medicine I had to be so careful to eat only hot food and drink department’s fellowship in humanitarian aid. Yax only bottled water. Back home in London, everything was an experienced responder to humanitarian was safe to eat. emergencies, and we found ourselves discussing the field of humanitarian aid more often than emergency Disease Matters medicine. He recommended I consider studying Growing up, my family made frequent visits to public health, and I fell in love with the field while Pakistan to visit my grandparents. Without fail, on earning an MPH. each trip, I would eat or drink something I’d been warned not to and would get a stomach bug. (We’ll Research Matters come back to the possible outcomes of stomach Public health combines nearly any discipline—for me, bugs later.) medicine and economics—in such effective, problem- This confusion—and later frustration—with the solving ways that I set aside the path of becoming a inequity stuck with me, and it still bothers me today. physician for a career as an epidemiologist. 6 Global Health Equity at the University of Michigan
Investing for Impact “I sought a path that would ensure my research could continue having a positive impact on human communities and also on how we do research.” MPH in hand, I moved to Johannesburg, dollar trials claiming that the provision of safe South Africa, to work for Population Services water and proper hygiene facilities—such as International, a large global health NGO with pit latrines—did not impact the rate of diarrhea a focus on reproductive health. I would learn a among children under five. lot about international health research. The main critiques of these studies focused Research can be used to inform public health on the quality of the interventions. We thought programs directly, which in turn can improve that something else was at play, namely, how people’s lives. the outcome itself—diarrhea—was defined and measured. Research can also have a dark side, if we’re not careful. When researchers from high-income As was the norm, these study teams had asked countries conduct studies without true local parents, very simply, if their child had had engagement—using my colleagues in South diarrhea at any time in the past three weeks. Africa as little more than a mailbox for IRB But parents might applications and HR for field workers, despite 1. not understand what diarrhea is these colleagues being internationally esteemed 2. forget whether their child had diarrhea and respected researchers—it is little more than 3. not want to answer honestly. a mechanism through which colonial legacies of power and exploitation continue to play out. All three were indeed the case, as my colleagues and I were able to show. In South Africa, I saw papers get published where local experts had conducted most or all But another, more important, factor was at of the work while foreign researchers took the play in assessing the two 2018 studies: the desired positions of principal investigator, lead interventions used in the trials were not directly author, and so on. related to diarrhea but instead to enteric infections generally. That is, these studies had Coming to the end of my contract in South used diarrhea as a proxy for enteric infection Africa, I desperately wanted to work in the and from there to evaluate the interventions. humanitarian aid space but had difficulty finding jobs. I decided that further schooling But is diarrhea a good proxy of enteric would be an effective way to contribute to the infection? As we see with COVID, the field and moved back to the UK to pursue a relationship between a disease and its PhD in epidemiology. symptoms is complex. • Having a cough does not mean somebody On my first day as a PhD student, my supervisor definitely has COVID let me know he was most interested in either pre-hospital care or diarrheal disease. Thinking • Feeling 100% in good health does not back to my childhood experiences visiting mean someone is COVID free Pakistan, the choice was obvious: diarrhea. We demonstrated the same for diarrhea— it does not make a good proxy of enteric Diarrheal Matters infections because evaluating symptoms and As I began my PhD in 2018, the world of water, interventions is too complicated. sanitation, and hygiene (WASH) was rocked The impact of our work on how other research by the results of two large-scale, multi-million teams might approach future studies of Impact Report 2022 7
Investing for Impact diarrheal diseases—which affect millions many publications we postdocs can produce of families every year and kill around 1.5M in a year nor in how much work we can do on children each year—helped see the importance various topics regardless of our level of interest. of research that accounted for human Instead, we are asked to conduct high-quality experience, including how study participants research that has a clear line of sight to experience an intervention and might report impact—to clearly defined outcomes that can information about their family’s health. improve lives. Anyone doing a postdoc in As my PhD work came to an end, I sought a the health sciences knows what an incredible path that would ensure my research could opportunity this is. I have the privilege in this continue having a positive impact on human program of working among and alongside communities and also—whenever possible— displaced populations in low- and middle- on how we do research. income countries, with excellent support and mentorship from University of Michigan I was delighted to discover the Center for faculty and staff and, most importantly, from Global Health Equity’s Impact Scholars faculty and staff in the countries where we are program, which is interested not only in how privileged to co-design and co-lead research. n Rego (second from right) in an urban informal settlement in the Mirpur neighborhood of Dhaka, Bangladesh, with research colleagues, including faculty from the International Centre for Diarrhoeal Disease Research, Bangladesh. 8 Global Health Equity at the University of Michigan
To Be a Good Steward Strengthening Systems for Healthier Women and Communities HaEun Lee spent years observing how she was perceived and treated, especially as a woman, in the various settings where she has lived. Her research aims to empower women and change social contexts so that we value women and their health more in all the decisions we make. Lee with Sister Dr. Priscilla Busingye—obstetrician and gynecologist and fistula surgeon at Saint Francis Hospital in Nsambya, Uganda—on a site visit to a camp that provides free postpartum surgical procedures. Impact Report 2022 9
After my first year of college, I traveled This poignant encounter in South Africa has to South Africa with a group of friends to stayed with me not only because of the details volunteer in the townships of Johannesburg. of human suffering but because such stories are On our way from one settlement to another, all too common, especially for those who are I met a young woman about my age sitting made vulnerable by the contexts of subjugation on the side of the road. We had a brief that pervade our communities. The story conversation in which she shared with me reminds me how difficult life is for so many of some of the harrowing details of why she was us, and that awareness motivates me to remain there and not able to be safely at home with focused on the community health engagement her family. work I conduct as a researcher. While I struggled at the time to find something A Bedside Steward Moves to say, I was feeling many things. I felt powerless because I didn’t know what to say into Research to her and because I knew larger systems I was born in South Korea and, due to my of oppression were behind her health crises parents’ jobs, had moved more than twenty times and those of many other women and girls. before graduating high school—between seven I felt shame from the stark contrast of our countries, attending twelve different schools, circumstances, knowing they had little to do and using three different languages in class. with our own merit or worth and everything to Throughout this time, I was observing how I was do with larger social circumstances over which perceived and treated, especially as a woman. neither of us have control. My experiences in South Africa were part of a More than anything, I felt a sense of larger process of career discernment for me. I had responsibility—that I needed somehow to already committed to nursing and art majors, two become a better steward of the privileges I had fields that can tangibly, practically touch people’s been given. lives. During senior-year clinical rotations—with Lee on a tour of the simulation lab at the Virika School of Nursing and Midwifery in Fort Portal, Uganda. 10 Global Health Equity at the University of Michigan
Investing for Impact “Women are painfully aware of the privileges we do and do not have. With the privileges I have, I am choosing to move through my research career with a sense of stewardship and responsibility.” my experiences from South Africa and many have the medication, equipment, and trained other contexts in my heart and on my mind—I staff whenever and wherever men, women, began to study in more depth the systemic, and children need them. And we believe that, structural, and policy-level issues that contribute by empowering local community members in every way to human illness and health. and politicians to work together in constructive ways, this project can help improve the overall As much as I had loved working closely with quality of Uganda’s rural healthcare. patients, I realized that working as a bedside nurse would no longer be my path. I became involved with nursing research, focusing on Research with Hope women’s health in minority populations. I joined When asked about my passion for research, a research team working with local, low-income I share how hopeful I remain that good women on basic menstrual, contraceptive, and research and evidence-based policy can help other reproductive education. And I worked on women around the world better protect and a pilot project educating women in underserved promote their own health and the health of the communities about coping mechanisms for systems and cultures around them, including depression and anxiety. their own family. In valuing women and their health, all people and communities have a As a doctoral student at the University of better chance at living up to their potential. Michigan School of Nursing, I worked on improving access to reproductive health Women are painfully aware of the privileges services. In my focus region—rural areas of the we do and do not have. With the privileges central African country of Zambia—I learned I have, I am choosing to move through my that many pregnant women there do not have research career with a sense of stewardship basic financial means, not even enough to and responsibility. secure transportation to a clinic, pay for basic medications, and purchase baby clothes. Even It has been almost a decade since I sat down in financially stable families, husbands control with the young woman in South Africa. She family resources and often will not prioritize was kind and generous to share her story with expenses related to pregnancy and childbirth. a stranger. Sadly, her story is far too common. As an Impact Scholar with the Center for Global But I live in hope. I do not yet know, fully, Health Equity, I work on an interdisciplinary what kind of life I must live to say I was a research team pursuing novel health good steward of all I’ve been given. I do governance approaches in Uganda. We know that, compared to ten years ago, today facilitate regular meetings between community I feel more empowered, less ashamed, and members and politicians where community extremely motivated to help women and their members express health care needs and communities be their fullest, healthiest selves. politicians share policy plans and progress. My research will continue to address the larger We train politicians on how to monitor and schemes of empowering women and changing supervise the implementation of research and our social contexts so that we value women and community information. The primary goal of their health more in all the decisions we make. n the project is ensuring clinics in rural areas Impact Report 2022 11
Espira (center) with a Center delegation in Nairobi, Kenya, learning about diagnostic radiology capabilities on a tour of Aga Khan University’s Cancer Center. Learning the Many Languages of Global Public Health Human health is more than what we can define using I was born in Kenya of mixed parentage. My mother studies and metrics, says Leon Espira. Our health is a is Russian, while my father is Kenyan. I was afforded reflection of our interactions with others as we seek the luxury of growing up in an atmosphere that enabled me to define myself not by cultural norms better lives for ourselves and our loved ones. but as the sum of all the cultures I straddle. Russian was my first language, Swahili my second, and Though I am a scientist by training—with a passion English I only learned in school. for discovery, analysis and understanding—I realize that the things that make us human are often not In as much as language defines our perspectives, tangible or quantifiable. I continue to see the world through my mixed heritage as well as these commonalities that are Human health is more than what we can define inherent in all of us. using studies and metrics but rather is a reflection of our interactions with others as we seek better lives In my late teens I moved to Winnipeg, Canada, to a for ourselves and our loved ones. world much removed from my childhood contexts. But with the common threads and common It is this recognition that has steered me in the languages that bind all humans together, I found direction of public health. Knowing that human making friends to be relatively easy. Soon enough, I health is about more than data helps me approach felt comfortable defining myself as Canadian. my work with a certain humility, one that recognizes a key truth in life—all the people I work with, in many After completing a masters degree in cardiac ways, seek the same things I do. physiology, I worked as an outreach coordinator in 12 Global Health Equity at the University of Michigan
Investing for Impact “Epidemiologists, like many researchers in public health, speak several languages.” underprivileged communities in Canada. I then research as such can only enhance our mission took a job in the Netherlands and, while there, of advancing the health of people in communities volunteered as a language coach. In these around the world. roles, my own privilege became clear to me, Because I know that research can only partly as did the bidirectional nature of outreach and describe the human experience, I am glad volunteer work. to be an epidemiologist. Epidemiologists, I have encountered many people during this like many researchers in public health, speak journey and recognize that the difference several languages. I’ve learned the languages between many of them and myself is tiny—yet of infectious disease, public policy, economics, I was afforded privileges that many do not medicine, and ecology. And these help me have. Kenya, however, remains my defining converse as a bidirectional researcher—trying experience. Being Kenyan grounds how I see to help communities understand disease and myself and the world—despite all the distance I prevent it, while at the same time learning have traveled from my childhood. from the communities to become a better epidemiologist. As I look to a career in global health, I continue to reach back to and draw upon these experiences. It is this versatility in public health that attracts They give me a sense of perspective. Research, me most—all the languages I get to speak and too, is inherently bidirectional, and embracing all the perspectives those languages offer. n Espira (right) with John Luseno (far left) and Hardley Malema (center) from Eco2librium visiting a household in Kakamega County, Kenya, to learn about water and sanitation access in rural areas. Impact Report 2022 13
Leveraging Expertise for Larger Funding Opportunities We take individual projects with big potential and connect them with others, adjusting the approach to amplify impact. The University of Michigan knows how to go after major external grants that help our researchers and our partners advance global health equity. Securing external revenue from funding sources like the National Institutes of Health and the National Science Foundation allows our global partners to address these wicked problems. Felix Agoi (right), AKU’s field coordinator, with Josh Ehrlich, research assistant professor with the U-M Institute for Social Research in Kilifi, Kenya, on a site where pilot testing for LOSHAK is being conducted. Agoi and Ehrlich were part of a team that received an NIH grant with seed funding from the Center.
Aga Khan University, Nairobi. Data Science and Emerging Tech for Earlier Interventions Psychology + Medicine + Data Science + Public Health In partnership with the Center, Aga Khan University and newborn health and mental health. It will also received a $6.5 million NIH grant to establish a leverage machine learning, an application of artificial intelligence, to identify creative solutions to aid cutting-edge data science hub, which has broad health service providers and policymakers within implications for implementing new technologies resource constrained environments. across the continent. “Early identification and intervention are critical Aga Khan University (AKU) is the recipient of a to a good prognosis for all health conditions,” $6.5 million grant to establish a cutting-edge data said Amina Abubakar, professor of psychiatry and science hub which will use artificial intelligence, director of the Institute for Human Development machine learning, and other emerging technologies at AKU and co-principal investigator. “However, in to improve health and care delivery in local many low- and middle-income countries (LMICs) communities. there is a dearth of tools that can be used for early identification of women, children, and young adults Utilizing Health Information for Meaningful impact at risk of poor physical and mental health.” in East Africa though Data Science (UZIMA-DS) will be the first initiative of its kind in the region. Funded The UZIMA-DS project will be a game changer in by a grant from the US National Institutes of Health two ways, Abubakar says, “First, we will leverage (NIH), the program will be led by AKU with partners existing data to develop tools and models that can in Kenya, the US and Canada. aid early identification of at-risk populations. Second, we will build the capacity of young Kenyan scientists UZIMA-DS looks to leverage data science to through post-doctoral and PhD fellowships to use proactively avoid adverse outcomes in maternal large data to inform health policies and practice.” Impact Report 2022 15
Investing for Impact “There is a dearth of tools that can be used for early identification of women, children, and young adults at risk of poor physical and mental health.” –Amina Abubakar, Aga Khan University UZIMA-DS will leverage machine learning to volume. The University of Michigan Center for identify creative solutions to aid health service Global Health Equity provided seed funding providers and policymakers within resource to support the initial partnership, which has constrained environment. potentially far-reaching implications for a technology previously associated primarily with Collaborating institutions include the high-resource settings. University of Michigan, the Kenya Medical Research Institute/Wellcome Trust Research “New technologies and innovative partnerships Programme, and the University of Ottawa. can help us address health data and service gaps in Kenya,” said Carl Amrhein, Provost and Vice “I am honored to be working with Professor President (Academic) at AKU. “Since the inception Abubakar and her colleagues at AKU who share of the UZIMA-DS, it has promised a unique and my passion for leveraging AI and machine powerful approach to improving health and learning to impact health equity and improve health equity in East Africa, which aligns well with people’s lives,” said Akbar Waljee, co-principal AKU’s commitment to global health.” investigator and professor of Internal Medicine at the University of Michigan, the top-ranked The grant is part of NIH’s Harnessing Data public research university in the US by research Science for Health Discovery and Innovation in Africa (DSI Africa) program, which aims to leverage data science technologies to develop solutions to the continent’s most pressing public health problems through a robust ecosystem of new partners from academia, government, and the private sector. AKU will implement the project through the Institute for Human Development and the Medical College. The Research Hubs formed out of this initiative will serve as a core component within the larger program, which will also consist of data science and innovation training programs, research on the ethical, legal, and social implications central to data science health research and innovation in Africa, and an open data science platform Akbar Waljee (left) and Amina Abubakar and coordinating center. n at Aga Khan University in Nairobi. 16 Global Health Equity at the University of Michigan
Felix Agoi (right), AKU’s field coordinator, with Josh Ehrlich in Kilifi, Kenya, on a site where pilot testing for the Longitudinal Study of Health and Aging in Kenya (LOSHAK) is being conducted. Advancing Healthy Aging in Africa Demography + Psychology + Medicine + Public Health + Economics An international team of researchers received an of Health (NIH) to address major gaps in population- NIH grant to address major gaps in population-level level data on aging in Kenya, one of Africa’s most populous nations. data on aging in Kenya, one of Africa’s most populous nations and one that expects its elderly population to “Kenya expects its elderly population to quadruple quadruple by 2050. by 2050,” says Anthony Ngugi, interim chair of Population Health at Aga Khan University (AKU) and co-principal investigator of the NIH grant.2 Africa is getting older. It is vital, says Ngugi, to begin studying “both The continent home to humanity’s origins and count- population-level trends and individual aging less ancient civilizations also has the world’s youngest trajectories to understand risk factors for health, population. But that is changing, and rapidly. disability, and well-being in the Kenyan context.” While today people over the age of 60 make up 5.6% Over the next thirty years, as Kenya becomes a place of Africa’s population, by 2050 that is expected to where people live longer and need different kinds of increase to over 15%.1 care, social structures will need to change. “Kenyan researchers and our partners can provide data that With enabling support from Center for Global Health informs the social and policy adjustments we need Equity, an international team of researchers has in Kenya to address the growing needs of an aging received a $338K grant from the National Institutes population,” Ngugi said. Impact Report 2022 17
“When the idea for the LOSHAK study was presented, I jumped on it, because I saw that the need was there.” –Anthony Ngugi, Aga Khan University The NIH grant supports pilot work to lay relationships—the trust and understanding groundwork for future NIH grant applications they’ve built—make all the difference in the aimed at launching the full-scale Longitudinal quality of the research.” Study of Health and Aging in Kenya (LOSHAK), Ngugi and Ehrlich will use preliminary data a cohort study of Kenyan adults aged 45 and findings collected during this initial phase and older. The study will eventually enroll to improve the study’s infrastructure and, thousands of participants and will follow them eventually, to propose a larger rollout in Kenya over the course of years. to field a nationally representative sample. In “Such an approach requires commitment from addition to continuing to build relationships participants and patience to see how results in communities that are new to working unfold over years,” explained Ngugi. “But data with researchers, the LOSHAK team faces from such a study is so valuable.” logistical challenges. “Kenya is a large country with many rural areas that can be difficult to Key focus areas include Alzheimer’s disease access. But it’s vital that rural as well as urban and related dementias, mental health, the populations be represented,” said Ehrlich. health and economic impacts of climate change and air pollution, and factors During his time with the Kaloleni/Rabai influencing late-life economic well-being. With platform, Ngugi has also established the rapid demographic changes and lack of relationships with leaders in local health corresponding research to understand them, systems, including local clinics and staff, the project seemed rather timely to Ngugi. and has ongoing collaborations with Kenya’s “When the idea for the LOSHAK study was National Ministry of Health. “Regional and presented, I jumped on it, because I saw that national health leaders are excited about the need was there,” he said. the project, because they understand the importance of studying aging,” Ngugi said. Connecting in Coastal Kenya The LOSHAK study utilizes an existing study Models Are Important platform, the Kaloleni/Rabai Community LOSHAK is also part of the Health and Health and Demographic Surveillance System, Retirement Study (HRS) network, a family a population-based research platform that of studies on aging in 45 countries modeled includes more than 14,000 individuals over the on the US HRS that began in the 1990s. “The age of 45 living in coastal Kenya.3 HRS provides extensive data to understand how health, economic, and family networks The Kaloleni/Rabai study is run by AKU, interact over time to affect aging, economic whose expertise and leadership “is central well-being, and social relations,” said Kenneth to the success of LOSHAK,” said Josh Langa, associate director of the HRS and Ehrlich—research assistant professor with co-investigator on the grant.5 the U-M Institute for Social Research, assistant professor of Ophthalmology and Currently, the only HRS network study in Africa Visual Sciences at Michigan Medicine, and is in South Africa, making LOSHAK only the co-principal investigator of the NIH grant.4 second such project in the region. Langa says “Our partners at AKU have strong relationships the Kenyan study has also provided a variety of with communities in this region, and these innovations. “LOSHAK is a poster child for how 18 Global Health Equity at the University of Michigan
Investing for Impact to get smart, talented folks in both countries together. Anthony and Josh, with support from “LOSHAK is a poster child for the Center for Global Health Equity, have put how to get smart, talented together a remarkable team.” folks in both countries together.” “And the way the LOSHAK study will apply population-level data to issues like climate –Kenneth Langa change will be pioneering work. Africa is Health and Retirement Study already experiencing many risks related to climate, and this study will help us see in great detail the connections among climate, aging, (UM), Alden Gross (JHU), Carlos Mendes and health,” Langa added. de Leon (Georgetown University), Edward Another key feature of HRS projects is that Miguel (UC-Berkeley), Muthoni Mwangi (AKU), all data collected are made publicly available. Roselyter Rianga (Moi University), Shaheen “The National Institute on Aging funds the HRS Sayed (AKU), and Akbar Waljee (UM). and ensures that all HRS network studies make LOSHAK is funded by the National Institute on their data public for researchers all over the Aging and the University of Michigan Center world,” said Langa. for Global Health Equity. The project has also Along with the population-based insights received additional funding from the Michigan on aging and health in Kenya and the cross- Center on the Demography of Aging and the national comparisons LOSHAK will provide, Harmonized Cognitive Assessment Protocol the study also advances the Center for Global (HCAP) Network. n Health Equity’s model of collaboration. “The Notes Center is committed to fostering sustainable relationships as we pursue collaborations 1. Wan He, Isabella Aboderin, and Dzifa Adjaye- with international partners, such as Aga Gbewonyo. US Census Bureau. Africa Aging: 2020 Khan University,” said Center director Joseph International Population Reports P95/20-1. US Government Printing Office, Washington, DC, 2020. Kolars. “Such relationships go hand-in-hand with projects that are truly co-designed, and 2. Anthony Ngugi, Interim Chair of Population LOSHAK is a remarkable example of bringing Health and Associate Professor of Epidemiology together two existing studies in a creative way.” and Population Health–Aga Khan University. Ngugi shares the commitment to this 3. Ngugi, Anthony, et al. “Cohort Profile: partnership model. “It is rare to come across The Kaloleni/Rabai Community Health and Demographic Surveillance System.” International a partner as developed and resourced as the Journal of Epidemiology 49/3 (June 2020):758–759e. University of Michigan who is truly willing to listen, truly willing to partner on an equal 4. Josh Ehrlich, Research Assistant Professor– basis, and is even willing to learn from us,” Institute for Social Research, Assistant Professor he said. “It is encouraging to work so closely of Ophthalmology and Visual Sciences–Michigan with our Michigan partners and to share Medicine. our capacities so together we can do this 5. Kenneth Langa, Associate Director–Health and important work in Kenya.” Retirement Study, Research Professor–Institute for Social Research, Cyrus Sturgis Professor Other members of the grant team include Felix of Medicine–Michigan Medicine, Professor of Agoi (AKU), Jessica Faul (UM), Muthoni Gichu Health Management and Policy–School of Public (Global Brain Health Institute), Jean Ikanga Health, Research Scientist–VA Center for Clinical (Emory), Pamela Jagger (UM), Elisa Maffioli Management Research. Impact Report 2022 19
Photo. Marcin Szczepanski, College of Engineering, University of Michigan Nurses Noelia Calel (center) and Virginia Xicay Garcia (right) joke with M-HEAL students during a meeting at a public health clinic in Santa Cruz, Guatemala. Calel and Garcia are demonstrating a new stethoscope that electronically records heart-sounds of patients in rural parts of Guatemala and sends them to a Guatemala City hospital. The stethoscope could eventually prevent major complications for infants born with congenital heart defects. Contextualized Engineering Design for Better Health Engineering + Information Science + Medicine Too little is known about how and when experienced environments of the technology’s anticipated use,” says engineering designers incorporate contextual factors Kathleen Sienko, professor of Mechanical Engineering in the University of Michigan College of Engineering. into their designs. A team of U-M researchers has been studying how context informs design decisions But little is known about how and when experienced throughout engineering design processes. engineering designers incorporate contextual factors into their designs. Does it matter if an engineer understands the context To help engineers—especially novices in in which a design solution will be employed? the profession—better incorporate the lived The answer might be an obvious yes. But with environments of local communities into their more and more processes and products being designs, a team of University of Michigan shared globally, implementing new technologies— researchers has been studying how contextual from healthcare to clean water to energy and information informs design decisions throughout communications—in local contexts is becoming engineering design processes. increasingly challenging. Through extensive interviews with experienced “The successful design of engineered technology engineering designers, Sienko and Kentaro Toyama, depends on a designer’s appropriate consideration professor of Information in the University of Michigan of context—the physical, social, and economic School of Information, are exploring exactly how 20 Global Health Equity at the University of Michigan
Investing for Impact “Designs that better address user needs are always prized but can be more difficult to actually procure.” –Kathleen Sienko, U-M College of Engineering engineers can more fully apply all of the inputs for local temperature, humidity, and other available to them in a design process. environmental realities, like high amounts of dust in the air or annual expectations of Findings from this work will be compared to drought and flooding. previous research with novice engineering designers to develop recommendations for Novice engineering designers, however, best practices in engineering design generally. rarely consider how politics can affect their design processes. It is important that The research involves semi-structured designers consider not only what utilities are interviews, observations, and document reviews available locally and how the reliability of local across three engineering design domains— transportation impacts supply and delivery of medical devices, consumer products, and products. Contextualized engineering design information and communication technologies. must also consider socio-cultural factors “Our results will help us understand which of consequence, including language and behaviors are transferable across engineering education access, local symbols and stigmas, design specialities, levels of experience, and and local aesthetics. use settings,” said Sienko. “We hope this “Whenever possible, we recommend using will lead to better design solutions for local context-appropriate graphics and adjusting populations in need of solutions to critical for language differences, selecting colors health concerns.” and symbols with meanings appropriate in Sienko, Toyama, and Grace Burleson, a PhD local contexts, and generally aligning design student in the College of Engineering, received decisions down to the last detail with local a pilot grant from the Center for Global Health preferences,” said Toyama. Equity to collect data on novice engineers. Finally, say Toyama and Sienko, designers “Context matters, especially in global health,” said should consider all facets of local and regional Burleson. “It’s well documented that when we fail politics. “We need to be asking what local to incorporate context it leads to design failure.” initiatives and policies could impact the Building on this enabling support, Sienko regulatory processes around the projects and Toyama recently received a $440K grant we hope to implement. Who are the local from the National Science Foundation (NSF) stakeholders and how can they be engaged to describe and better understand the use of positively as supporters of your project?” contextual factors in engineering design. Sienko said. They will focus on multiple categories of Sienko and Toyama hope their research will contextual factors that can affect design and lead to a range of innovations in processes and design implementation—environmental and products designed with local environments and infrastructure factors, socio-cultural factors, local stakeholders front and center. and local political factors. “Anyone working in global health knows that Based on Burleson’s preliminary results, novice new challenges are constantly emerging,” engineering designers readily consider local said Sienko. “Designs that better address climates when designing devices. For example, user needs are always prized but can be more they aim to select materials that account difficult to actually procure.” n Impact Report 2022 21
CGHE Funded Projects 1 Mexico Liberia 2 4 Ghana Ecuador 2 Peru 1 $787,000 Research Investments # Total number of Center-funded projects in the country Some impact projects operate in more than one country. 22
2 Nepal 2 Bangladesh Thailand 1 2 Nigeria 2 Uganda 5 Kenya Indonesia 1 1 Rwanda 2 Zimbabwe Thematic Priorities Based on potential for impact, institutional strengths, and perceived needs, Center leaders and stakeholders 2 identified four primary themes to guide initial collaborations and efforts. South Africa • Strengthening systems to improve health and health equity, including creative approaches with the private sector—human resource development, collaborative care models, supply chain and access • Informing policy and programming related to social and environmental determinants of health—climate change, food security, education, health economics, and economic development • Developing technical solutions for health equity—artificial intelligence and data science approaches, telehealth tools, and systems • Empowering women as effectors of health for themselves, their families, and their communities 23
Health and Maternal Challenge Socioeconomic Impacts Depression in Rural Family Planning Group of Water Intermittency Uptake in Ghana and Urban Ecuador in Mexico Grants Collective Solutions for Complex Problems Challenge Groups comprise faculty from across the University of Michigan who share Anthropology + Anthropology + Public complementary expertise Nursing + Medicine Public Health + Health + Psychiatry + and interests. + Public Health Engineering Environment These interdisciplinary Sergio Bautista Fu Yu Chang Sarah Compton communities explore National Institute of University of Cuenca-Kaleidos U-M Medical School potential partnerships and Public Health-Mexico Center for Interdisciplinary Veronica Dzomeku projects that align with their Ethnography José Luis Figueroa-Oropeza Kwame Nkrumah University of respective interests, with an National Institute of Mayra Flores Science and Technology-Nursing eye toward collaborations Public Health-Mexico University of Cuenca-Kaleidos Jody Lori that carry the greatest Center for Interdisciplinary Jaclyn Goodrich U-M School of Nursing Ethnography potential for impact. U-M School of Public Health Cheryl Moyer Rebecca Hardin Branko Kerkez U-M Medical School Challenge Groups meet U-M College of Engineering U-M School for Environment and Sustainability Emmanuel Nakua regularly and provide Elizabeth Roberts Kwame Nkrumah University of opportunities for research- U-M College of Literature, Gwenyth Lee Science and Technology-Public ers to share ideas and Rutgers University-Epidemiology Science, and the Arts Health receive feedback on current Brisa Sánchez Maria Muzik Easmon Otupiri projects. Many members U-M Medical School Drexel University, Public Health Kwame Nkrumah University of value this time together Mara Téllez Rojo Jorge Núñez Science and Technology-Population, with colleagues in other University of Cuenca-Kaleidos Family, and Reproductive Health National Institute of Center for Interdisciplinary units who nevertheless Public Health-Mexico Ethnography Emily Treleaven understand their goals, U-M Institute for Social Research James Wagner Maka Suarez approaches, and passion U-M Institute for Social Research University of Cuenca-Kaleidos for global health. Krista Wigginton Center for Interdisciplinary Challenge Group U-M College of Engineering Ethnography Empowering As experts from around Women and the university convene to Challenge Group Challenge Group Communities discuss wicked problems Climate Empowering in global health, they Vulnerability Women and The project explores build communities of and Health Communities the know-do gap among practice that advance postpartum Ghanaian collective solutions. The project seeks to women to identify potential The project documents the interventions that enable understand the effects of The Center has funded a multiple facets of maternal them to realize fertility goals. intermittent water supply mental health in Ecuador number of high-impact on chronic disease and and explores how health projects—shown here—that economic and gender professionals understand, inequality globally, and to arose from these respective diagnose, and treat develop evidence-based Challenge Groups. maternal depression. approaches to address them. 24
Investing for Impact Gender-Based Empowerment Empowerment Dementia Violence on among LBQ Women among Indigenous Biometrics in the University Campuses in Western Kenya Women in Thailand Chitwan Valley in Sub-Saharan Africa of Nepal Social Work + Anthropology + Public Health + Nursing + Medicine Psychology + Medicine Public Health + Medicine + + Social Work + Public Health Medicine Social Sciences Michelle Munro-Kramer Gary Harper Tawatchai Apidechkul Dirgha Ghimire U-M School of Nursing U-M School of Public Health Mae Fa Luang University U-M Institute for Social Research Sarah Compton Laura Jadwin-Cakmak Amanda Flaim Kenneth Langa U-M Medical School U-M School of Public Health Michigan State University, U-M Medical School Sociology Lisa Fedina Ashley Lacombe-Duncan Carlos Mendes de Leon U-M School of Social Work U-M School of Social Work Chutimav Morlaeku Georgetown University, Indigenous Mountain Peoples Public Health University of Cape Coast, Ghana Anita Mbanda Education and Cultural Association Kwame Nkrumah University of Western Kenya LBQT Janak Rai of Thailand Science and Technology, Ghana Feminist Forum Tribhuvan University Cheryl Moyer Takoradi Technical University, Sara McClelland Meeta Sainju Pradhan U-M Medical School Ghana U-M Women’s and Gender Studies Institute for Social and Malee Sitthi Kriengkrai Environmental Research, Nepal University of Liberia, Liberia Wilson Odero Chiang Mai University Obafemi Awolowo University, Maseno University Uttam Sharma Nigeria Laura Rozek Institute for Social and Becky Odhiambo Georgetown University, Environmental Research, Nepal Sefako Makgatho Health Sciences Western Kenya LBQT Public Health University, South Africa Feminist Forum Emily Treleaven University of KwaZulu-Natal, Caroline Rucah U-M Institute for Challenge Group South Africa Western Kenya LBQT National University of Science Feminist Forum Social Research Data Science and Technology, Zimbabwe Challenge Group Challenge Group The project addresses health Empowering Empowering inequities in the older adult Challenge Group Women and Women and population of Nepal. As Empowering Communities Communities the size of the older adult population grows, increasingly Women and larger numbers of adults Communities Kenya is home to an are affected by Alzheimer’s increasingly visible sexual and Working with local partners, disease and related gender minority community. the project develops dementias (ADRD). The The project will conduct Through a mix of qualitative ethnographic and related project designs and conducts a cross-country campus individual in-depth interviews qualitative instruments to a pilot test of the procedures climate survey to inform and focus group discussions, explore how indigenous and logistics of collecting development of culturally, the project takes first steps women in Thailand con- blood samples in the context contextually appropriate toward developing policies, ceptualize empowerment of a new large survey study of interventions for universities programs, and services that and its relationship to their ADRD in Nepal. in sub-Saharan Africa. promote health equity among health and the health of their LBQ women in Kenya. children. 25
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