2021 Queensland Clinical Sciences Symposium - Building Bridges and Breaking Boundaries
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2021 Queensland Clinical Sciences Symposium
Building Bridges and Breaking Boundaries
Saturday 20 March 2021
Translational Research Institute, Brisbane
About the Academy
The Australian Academy of Health and Medical Sciences is the impartial, authoritative, cross-sector
voice of health and medical science in Australia. We are an independent, interdisciplinary body of 426
Fellows – elected by their peers for their distinguished achievements and exceptional contributions to
health and medical science in Australia. Collectively, they are a representative and independent voice,
through which we engage with the community, industry and governments.
The Academy is uniquely positioned to convene cross-sector stakeholders from across Australia to
address the most pressing health challenges facing society.
We focus on the development of future generations of health and medical researchers, on providing
independent advice to government and others on issues relating to evidence based medical practice
and medical researchers, and on providing a forum for discussion on progress in medical research with
an emphasis on translation of research into practice.
The Academy is registered with the Australian Charities and Not-for-profits Commission (ACNC) and is
endorsed as a deductible gift recipient.
www.aahms.org
@MedSciAcademy @AAHMS_Health
2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
WELCOME
Welcome
to Life as a Clinician Scientist
Why consider life as a clinician scientist?
Clinician scientists possess an invaluable skillset that allows them to solve clinical questions and provide
deep scientific insights into human biology. Today we showcase the many pathways that can lead you to
this exciting and rewarding career, which leads to a lifetime of challenge and discovery. Clinical work and
science are a unique combination that allow you to work with patients and take your insights from the
bedside to answer fundamental scientific questions.
In 2021, you cannot go it alone. Collaborating with scientists from many disciplines is both fun and
inspiring. Health and medical research can take you down surprising paths towards areas you would
never have expected. A career in research can be tough, but the often lengthy journey is rich, varied and
fulfilling.
The Australian Academy of Health and Medical Sciences exists to advance health and medical research in
Australia and its translation into benefits for all, by fostering leadership within our sector, providing expert
advice to decision makers, and engaging patients and the public. One of our key objectives is to grow and
mentor Australia’s future generations of health and medical researchers, and today’s symposium is aiming
to do just that.
We are honoured that nationally and internationally recognised clinician scientists from Queensland and
beyond have kindly agreed to share their wisdom and expertise today.
We are grateful for the generous support of our sponsors. Our platinum sponsors are The University
of Queensland's Faculty of Medicine, Griffith University Menzies Health Institute and the Translational
Research Institute. Our gold sponsor is QIMR Berghofer and our silver sponsor is the Queensland Brain
Institute-The University of Queensland. This event would not be possible without their support.
Funding for this event has been provided by the Australian Government. The views expressed at the event
do not necessarily reflect the views of the Australian Government.
We encourage you to join the twitter conversation using #LACS2021 and @AAHMS_Health and we hope
you enjoy the symposium!
Symposium Convenors
Professor Isaac Maisah Catherine Chloe
David Whiteman Carmichael Joarder Lawton Yap
Chair Co-Chair
We need your feedback to continue providing these type of events.
Please complete a short survey at bit.ly/QCSS-2021-survey
2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
“You have three careers in a day –
a doctor, a scientist and a teacher”
Laureate Professor Ingrid Scheffer AO FRS FAA PresAHMS
President, Australian Academy of Health and Medical Sciences
Chair of Paediatric Neurology Research, The University of Melbourne and
Florey Institute of Neuroscience and Mental Health
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2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
PROGRAM
SATURDAY 20 MARCH 2021
8.15 am Registration
SESSION 1 Building Bridges
9.00 am Professor David Whiteman Welcome to the 2021 Queensland
AM FAHMS and Isaac Carmichael Clinical Sciences Symposium
9.15 am Professor Claire Wainwright From genetics to the pharmaceutical market for
AM FAHMS cystic fibrosis therapies
9.40 am Distinguished Professor Dietmar Interdisciplinary collaboration in surgery -
W. Hutmacher FAHMS and engineering the world's first 3D bone implant
Dr Michael Wagels
10.20 am Morning tea
10.50 am Professor Bala Venkatesh FAHMS Building capacity and culture in translational
intensive care research
11.15 am Professor Tammy Hoffmann The ‘other’ type of translational research
OAM FAHMS
11.40 am Panel Discussion Building a career in translational research
Chair: Professor David Whiteman
AM FAHMS
12.20 pm Lunch
SESSION 2 Breaking Boundaries
1.20 pm Emeritus Professor Stem cells as models for brain diseases and drug
Alan Mackay-Sim discovery
1.50 pm A/Prof Clair Sullivan Digital health to improve health outcomes
2.15 pm Dr Eamonn Eeles Ageing. Challenges, opportunities and innovations
2.40 pm Afternoon tea
3.10 pm Panel Discussion Building a career in translational research –
Chair: Professor David Whiteman perspectives across career stages
AM FAHMS
A/Prof David Cavallucci Dr Cameron Snell
(hepato-pancreatico-biliary surgery) (pathology)
Dr Michelle Roets Dr Monica Ng
(anaesthetics) (renal medicine)
4.00 pm Event close
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2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
SPEAKERS
Professor David Whiteman AM FAHMS
Medical Epidemiologist and Deputy Director,
QIMR Berghofer
Professor David Whiteman is a medical epidemiologist with a special interest in the causes, control
and prevention of cancer. He received his medical degree from the University of Queensland in 1991,
and his PhD in cancer epidemiology in 1997. Professor Whiteman has an international reputation for
research into melanoma and skin cancer, and the public health aspects of cancer control. He has more
than 350 peer-reviewed research publications, an H-index of 72 and has been awarded more than $50
million in competitive research grants as Chief Investigator. In addition to his research activities, he is
Deputy Director of QIMR Berghofer, a Fellow of the Australian Academy of Health and Medical Sciences,
a Fellow of the Australasian Faculty of Public Health Medicine, and Honorary Fellow of the Skin Cancer
College of Australasia. In 2019, he was made a Member of the Order of Australia for his services to cancer
epidemiology.
Professor Claire Wainwright AM FAHMS
SMO Respiratory & Sleep Medicine,
Co-Lead Cystic Fibrosis Services,
Children's Health Queensland
Professor Claire Wainwright is a paediatric respiratory physician and Co-Lead for cystic fibrosis (CF) services
at the Queensland Children’s Hospital in Brisbane which manages around 450 children with CF across
Queensland and northern NSW. She is a Professor of Paediatrics and Child Health at the University of
Queensland and her research interests include clinical trials, development of lung disease in CF, airway
microbiology, and patient reported outcomes in CF.
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2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
SPEAKERS
Distinguished Professor Dietmar W. Hutmacher
FAHMS
Director, ARC ITTC in Additive Biomanufacturing;Director,
Centre in Transformative Biomimetics in Bioengineering,
Queensland University of Technology
Distinguished Professor Hutmacher is a biomedical engineer, an educator, an inventor, and a creator of new
intellectual property opportunities. He is committed to fostering transformative research and pedagogical
innovation as well as programs that create an entrepreneurial mindset amongst faculty and students. He
directs the Centre for Regenerative Medicine and the ARC Training Centre in Additive Biomanufacturing
at QUT, an interdisciplinary team of researchers including engineers, cell biologists, polymer chemists,
clinicians, and veterinary surgeons.
Professor Hutmacher is an internationally recognized leader in the fields of biomaterials, tissue engineering
and regenerative medicine with expertise in commercialization. He has translated a bone tissue
engineering concept from the laboratory through to clinical application involving in vitro experiments,
preclinical studies and ultimately clinical trials. His recent research efforts have resulted in traditional
scientific/academic outputs as well as pivotal commercialisation outcomes. His pre-eminent international
standing and impact on cross-disciplinary fields are illustrated by his ranking as an highly cited researcher.
Dr Michael Wagels
Deputy Director, Department of Plastic and Reconstructive
Surgery, Princess Alexandra Hospital; Senior Lecturer,
The University of Queensland
Michael Wagels is Deputy Director of the Department of Plastic and Reconstructive Surgery at the Princess
Alexandra Hospital with a conjoined academic appointment as Senior Lecturer at the University of
Queensland. He completed a BMedSci undergraduate research degree in 1999 and an MBBS undergraduate
medical degree in the same year. He completed his FRACS in Plastic and Reconstructive Surgery in 2012 and
was awarded a PhD by the University of Queensland in 2014. His theses evaluated amputation in severe
lower limb trauma and the behaviour of auto-transplanted muscle for traumatic lower limb injuries.
Michael has a special interest in complex lower limb reconstruction, hand and wrist surgery, reanimation of
the upper limb and head and neck reconstructive surgery. He is also interested in the translational aspects of
tissue engineering for complex reconstructive defects. In 2019 he was appointed Director of the Australian
Centre for Complex Integrated Surgical Solutions. This organisation is based at the Translational Research
Institute and is dedicated to making clinically applied digital innovations accessible to clinicians and the
patients that they treat.
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SPEAKERS
Professor Bala Venkatesh FAHMS
Director of Intensive Care, Wesley Hospital; Professor of
Intensive Care Medicine, The University of Queensland and
the University of New South Wales; Professorial Fellow at
the George Institute for Global Health, Sydney Australia
Professor Bala Venkatesh is Director of Intensive Care at the Wesley Hospital, Pre-Eminent specialist in
Intensive Care Medicine at the Princess Alexandra Hospital, Brisbane, Professor of Intensive Care Medicine
at the University of Queensland, and at the University of New South Wales, and Professorial Fellow at the
George Institute for Global Health, Sydney Australia. He is currently the Chair of the QLD Statewide Sepsis
Steering Committee.
He has completed Fellowship training in Internal Medicine, Anaesthesia and Intensive Care Medicine. He
then undertook a research degree from the University of Birmingham, UK which led to the award of an
MD. He pioneered the development of a continuous blood gas monitoring system which reached clinical
application.
He served as the President for the College of Intensive Care Medicine of Australia and New Zealand
between 2014-2016.
He is the Principal Investigator of the NHMRC funded multi-center international ADRENAL trial which
is largest septic shock trial to date. This was published in the New England Journal of Medicine. He is
currently supervising 4 PhD students.
He has been involved in 4 major RCTs of sepsis. His research interests include glucocorticoid physiology in
critical illness including the development of the idea of the "sick euadrenal state", sepsis and vitamin D in
critical illness. He has published more than 200 papers, and 40 book chapters. He is currently running 4
COVID-19 trials in India.
Professor Tammy Hoffmann OAM FAHMS
Professor of Clinical Epidemiology & NHMRC Senior
Research Fellow, Institute for Evidence-Based Health Care,
Bond University
Tammy is Professor of Clinical Epidemiology and NHMRC Senior Research Fellow at the Institute for Evidence-
Based Health Care, Bond University, and a Fellow of the Australian Academy of Health and Medical Sciences.
Tammy’s research spans many aspects of shared decision making, evidence-based practice, and maximising
the translation of evidence to assist clinicians, patients, and the public to make informed health decisions.
She is also Co-Director of the Australasian Equator Centre, which is an international initiative that seeks
to improve the reliability and value of published health research literature by promoting transparent and
accurate reporting and wider use of robust reporting guidelines. Tammy has over 250 publications, including
many articles in leading journals such as JAMA, BMJ, JAMA Internal Medicine, PLOS Medicine, and BMC
Medicine. Tammy has been involved in the development of a number of reporting guidelines including the
2020 PRISMA statement and led the development of the TIDieR (Template for Intervention Description and
Replication) checklist and guide.
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2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
SPEAKERS
Emeritus Professor Alan Mackay-Sim
Neuroscientist and Stem Cell Scientist, Griffith University;
2017 Australian of the Year
2017 Australian of the Year, Professor Alan Mackay-Sim is a neuroscientist and stem cell scientist. A
global authority on the human sense of smell, Alan uses his knowledge of regeneration of olfactory
sensory neurons to move from the lab to the clinic. In preclinical work Alan and his team showed that
transplantation of nasal cells (“olfactory ensheathing cells”) could restore motor function after spinal
cord injury. He then led the world’s first Phase I clinical trial demonstrating the safety of this procedure
in human paraplegia. This research is continuing at Griffith University’s Spinal Injury Project, with a Phase
II trial planned in the near future. Professor Mackay-Sim has developed a unique “NeuroBank”, neural
stem cells from the nose from 300 patients and controls used to understand the biological bases of brain
diseases and for drug discovery. In Hereditary Spastic Paraplegia, a rare neurodegenerative condition,
patient stem cells have led to a potential new therapy being taken to Phase I/II trial.
Associate Professor Clair Sullivan
Head, UQ Digital Health Network;
Consultant Endocrinologist and Medical Informatician
Associate Professor Clair Sullivan graduated with Honours in Medicine from UQ and a Research Doctorate
in Medicine from the University of Leeds. She is a fellow of both the Royal Australasian College of
Physicians and the Australian College of Health Informatics. She has been appointed Associate Professor
of Medicine in Clinical Informatics at the University of QLD and is Adjunct Professor, Faculty of Health,
Queensland University of Technology. She is widely published in clinical informatics and serves on several
national advisory boards for digital health. Clair is currently the Head of The University of Queensland's
Digital Health Network.
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2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
SPEAKERS
Dr Eamonn Eeles
Consultant Physician and Geriatrician,
The Prince Charles Hospital
Dr Eeles is a consultant physician and geriatrician and a keen researcher in the field of dementia
and delirium. Dr Eeles is research council chair at TPCH, Head of research IMS, Statewide advisor to
the Queensland Brain Institute, member of Statewide Dementia Network and Australasian Delirium
Association committees.
Associate Professor David Cavallucci
Hepato-Pancreatico-Biliary Surgical Oncologist;
Senior Lecturer, The University of Queensland
Associate Professor David Cavallucci is an Hepato-pancreatico-biliary surgical oncologist. He is a graduate
of the two-year ANZHPBA post-fellowship program in HPB surgery as well as the surgical oncology and
abdominal transplantation Fellowship at the University of Toronto.
He has a special interest in minimally invasive pancreatic and liver surgery with a broad experience of
laparoscopic surgery and developing robotic surgery. Outside of oncology, he manages benign biliary
disease including the laparoscopic management of bile duct stones and the surgical management of acute
and chronic pancreatitis.
Having completed a Masters degree in Biostatistics, he has published on the use of Propensity Scores and
novel weighting techniques in observational surgical research. He is active in teaching and maintains a
strong interest in clinical and translational research. A/Prof Cavallucci is President of the ANZHPBA, and
active on the Education and Training committee of the IHPBA and the HPB Journal Editorial board.2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
SPEAKERS
Dr Michelle Roets
Consultant Anaesthetist & Lead, Intraoperative
Cell Salvage Service, Royal Brisbane and Women’s Hospital
Dr Michelle Roets is a consultant anaesthetist, lead of the intraoperative cell salvage (ICS) service at
the Royal Brisbane and Women’s Hospital (RBWH) and is currently a PhD student with the University of
Queensland (UQ), studying the cost and immunological benefits of ICS.
She did her undergraduate medical training at the University of Pretoria (South Africa), completed a
fellowship in Anaesthesia, Intensive care and Pain Medicine at the Royal College of Anaesthetists of Ireland,
a Master’s degree in Clinical Research Administration with the Walden University (Baltimore, Maryland,
USA) and a fellowship with the Australian and New Zealand College of Anaesthetists (Australia).
She was involved in the first implementation of ICS in Obstetric Anaesthesia in Ireland, co-author of the
“Guidance for the Provision of ICS” documents with the National Blood Authority in Australia (2014), ICS
chapters in the Australasian Anaesthesia textbook (2017 & 2019) and invited presenter (21 national and
two international conferences).
Dr Cameron Snell
Medical Director, Mater Pathology;
Anatomical Pathologist and Honorary Senior Lecturer,
The University of Queensland
Dr. Cameron Snell is the Medical Director at Mater Pathology in Brisbane. He has a strong interest in
translational cancer research and completed his DPhil “Mitochondrial Modulators of hypoxia related
pathways in tumours” in 2014 at the Nuffield Department of Clinical Laboratory Sciences, University of
Oxford. He leads the Breast and Lung tumour streams at the Mater Hospital Brisbane and has established
the Mater-IHBI Breast Cancer Biobank.
Dr. Snell holds academic appointments at the Mater Research Institute, University of Queensland and is an
Adjunct Associate Professor at the Queensland University of Technology.
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SPEAKERS
Dr Monica Ng
Renal Advanced Trainee, Princess Alexandra Hospital;
Post-doctoral Researcher,
Conjoint Kidney Research Laboratory;
Adjunct Research Fellow, Institute of Molecular Biosciences
Dr Monica Ng is a renal advanced trainee at Princess Alexandra Hospital, Postdoctoral researcher at the
Conjoint Kidney Research Laboratory and Adjunct Research Fellow at Institute of Molecular Biosciences.
She completed medical school with first class honours at the University Queensland in 2014 and
completed her PhD in blood transfusion and vascular modelling in 2019. Her postdoctoral research
involves using molecular methods such as flow cytometry and spatial transcriptomics; as well as large data
analyses to improve the diagnosis and treatment of glomerulonephritides.
Monica has presented her research in various international journals and conferences; and acts as an
invited peer reviewer for journals such as Medicine, BMJ Open, BMJ Case Reports and BMC Nephrology.
Monica also participates in teaching activities and is a Lecturer at Faculty of Medicine, University of
Queensland. In her spare time, Monica enjoys hiking and kayaking.
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PLATINUM SPONSORS
For more than a century, The University of Queensland (UQ) has maintained a
global reputation for delivering knowledge leadership for a better world.
The most prestigious and widely recognised rankings of world universities
consistently place UQ among the world’s top universities.
UQ has also won more national teaching awards than any other Australian
university. This commitment to quality teaching empowers our 53,600 current
students, who study across UQ’s three campuses, to create positive change for
society.
Our research has global impact, delivered by an interdisciplinary research
community of more than 1500 researchers at our six faculties, eight research
institutes and more than 100 research centres.
The Faculty of Medicine
The University of Queensland’s Faculty of Medicine is an internationally
recognised provider of world-class education and research. The Faculty of
Medicine offers Australia’s largest medical degree program for graduates and
school-leavers. Undergraduate and postgraduate programs are available in the
disciplines of Medicine, Health Sciences, E-Health, Mental Health, Biomedical
Sciences and Public Health. The Faculty possesses enormous strengths spanning
research, teaching, industry engagement and clinical practice in disciplines
ranging from the basic sciences, biomedical research and development, to clinical
trials and public health.
The Menzies Health Institute Queensland (MHIQ) undertakes research across
the lifecycle to identify key factors that influence health. From this, we develop
and test strategies to improve health and wellbeing for individuals, families and
communities.
With more than 580 of the world’s leading biomedical scientists, clinical
researchers and research candidates, Griffith’s MHIQ continues to achieve
remarkable outcomes.
Four overarching programs—Disability and Rehabilitation, the Economic, Policy
and Innovation Centre for Health Systems (EPIC Health Systems), Healthcare
Practice and Survivorship, and Infectious Diseases and Immunology—encapsulate
our research strengths and align with local and national health priorities.
Underpinning the work of these programs is a focus on innovation, data science,
research translation and meaningful clinical and community partnerships.
The Translational Research Institute (TRI) is an Australian-first initiative of
‘bench to bedside’ medical research. TRI’s unique model combines clinical
and translational research to advance progress from laboratory discovery to
application in the community. The work is driven by the needs of patients
with research focused on cancer, dermatology, gastroenterology, immunology,
genomics and trauma.
Located in Brisbane, Queensland at the Princess Alexandra Hospital, TRI is one of
few institutes worldwide where new biopharmaceuticals and biotech treatments
can be researched, discovered, manufactured, and clinically tested in one location.
Created by its founding partners: The University of Queensland, Queensland
University of Technology, Mater Research and Queensland Health, TRI is now
the base for a powerhouse of over 1,000 clinicians, researchers and support
staff working together with patients to solve health challenges faster and more
efficiently.
Australian Academy of Health and Medical Sciences 132021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
GOLD SPONSOR
QIMR Berghofer Medical Research Institute is a world-leading translational
research institute where research develops from the laboratory bench through to
the patient’s bedside. With almost 900 scientists, students and support staff, and
more than 50 state-of-the-art laboratories, QIMR Berghofer is one of Australia’s
largest and most successful institutes. For over 70 years, QIMR Berghofer has
led advances in the understanding, prevention, control, diagnosis and treatment
of disease. Today, in collaboration with research institutions, governments and
industry throughout the world, QIMR Berghofer focuses on cancer, infectious
diseases, chronic disorders and mental health, and has developed impressive
capability in genomics across these programs.
14 Australian Academy of Health and Medical Sciences2021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
Notes
Australian Academy of Health and Medical Sciences 152021 QUEENSLAND CLINICAL SCIENCES SYMPOSIUM
Australian Academy of Health and Medical Sciences
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Woolloongabba, QLD 4102 Woolloongabba, QLD 4102
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www.aahms.org | info@aahms.org | T: +61 (0) 7 3102 7220
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Meeting 0672019
| October
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