DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH

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DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
DIAGNOSTIC SERVICE PORTFOLIO

                           POULTRY
                              CONSULTING
       Dr. Swaantje Rönchen                         Dr. Diana Petzoldt
    Phone: +49 44 73 / 94 38 - 52              Phone: +49 4473 / 94 38 - 786
        roenchen@anicon.eu                          petzoldt@anicon.eu

         AniCon Labor GmbH | Muehlenstr. 13 | 49685 Hoeltinghausen | Germany
              Phone +49 44 73 94 38 30 | info@anicon.eu | www.anicon.eu
DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No       Pathology
         19230         Sampling "basic"
         19300         Sampling "extended"
         19240         Pathological-anatomical reporting
         12690         Parasitologic investigation (mucosal scraping; microscopic examination)
         12690         Parasitologic investigation (flotation/sedimentation; microscopic examination)
         10318         Parasitologic investigation (feces: coccidia oocyst counting acc. to McMaster)
         10358         Patho-histological examination (per tissue sample)

         Item-No       Material for sampling
         27960         AniCard with 10 spots (FTA®-card technology) (per card)
         28560         Reaction tube 1.5 ml (per 500 tubes)
         28520         Tube 13 ml and plug (per 500 tubes)
         28580         Salmonella-sampling swab (with neutralizer solution; per 50 swabs)
         28590         Boot/Sock swab (per 100 swabs)
         23250         MALDI-TOF MS target (single use)
         28550         Sampling beaker sterile (per 5 beaker)
         29650         Sampling beaker with formalin for pathohistology (per beaker)
         28570         Swab for anaerobic bacteria (per 50 swabs)
         15160         Fine swab (aluminium) with transport medium (per 100 swabs)
         12810         Fine swab (aluminium) without transport medium (per 100 swabs)
         19910         Swab (wooden) without transport medium (per 100 swabs)
         26780         Swab with preservative agent (Mycoplasma or virus culture) (per 50 swabs)
         27460         Swab with preservative agent (Brachyspira culture) (per 50 swabs)
         19930         Paper strips (ELISA) (per 100 strips)

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                           Diagnostic Service Portfolio Poultry                                                  Page 2 of 9
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DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No           ELISA
            20520             Avian Encephalomyelitis Virus (AEV)
            11310             Avian Metapneumovirus A & B (aMPV / ART / TRT / SHS)
            11680             Bordetella avium (turkey)
            20530             Chicken Anemia Virus (CAV)
            19830             Chicken Astrovirus (CAstV; cave: group B only)
            10231             Egg Drop Syndrome-76 Virus (EDS-76 / DuAdV)
            19110             Fowl Adenovirus (FAdV)
            12860             Hemorrhagic Enteritis Virus of Turkeys (HEV)
            12930             Infectious Bursitis Virus (IBDV / Gumboro)#
            20490             Infectious Bursitis Virus (IBD plus; in case of vaccination with Vaxxitek ® IBD)
            13280             Infectious Bronchitis Virus (IBV)
            17390             Infectious Laryngotracheitis Virus (ILTV)
            12830             Influenza Virus Type A (multispecies / blocking)
            14470             Influenza Virus - H5 specific (multispecies / blocking)
            14480             Influenza Virus - H7 specific (multispecies / blocking)
            10730             Mycoplasma gallisepticum (Mg)
            10740             Mycoplasma synoviae (Ms)
            12660             Mycoplasma meleagridis (Mm)
            16470             Newcastle Disease Virus (aPMV-1)
            10840             Ornithobacterium rhinotracheale (ORT)
            16580             Pasteurella multocida (chicken, turkey)
            15800             Reovirus (ARV)
            10750             Riemerella anatipestifer (turkey & duck only, please indicate species)
            15680             Salmonella Group B & D (incl. SE & ST; chicken)
                    # vaccination   date prediction is provided upon request (at no extra charge)

            Item-No       HI – Hemagglutination Inhibition Testing
            14520         Egg Drop Syndrome-76 Virus (EDS-76 / DuAdV)
            17380         Influenza H-Type (H1, H5, H6, H7, H9, further upon request)
            15950         Avian Paramyxovirus-1 (Newcastle Disease Virus, NDV, aPMV-1)
            15970         Avian Paramyxovirus-3 (aPMV-3)

            Item-No       SSA – Serum Slide Agglutination
            10780         Mycoplasma gallisepticum (Mg)
            10790         Mycoplasma meleagridis (Mm)
            10860         Mycoplasma synoviae (Ms)
            10800         Salmonella Gallinarum Pullorum (SGP)

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                 Diagnostic Service Portfolio Poultry                                            Page 3 of 9
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DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No       Microbiology
            10580         Bacteriological examination (per swab / animal)
            13920         Bacteriological examination package$ 1-5 chicks / poults
            13790         Bacteriological examination package$ 6-14 chicks / poults
            12750         Biochemical differentiation - API
            18400         MALDI-TOF MS (species determination by mass spectrometry bacteria)
            24300         MALDI-TOF MS (species determination by mass spectrometry mould)
            10590         Resistance testing (ADT)
            10064         Resistance testing (MIC)
            14030         Archival storage (bacterial & viral strains)
            23860         Cultural enrichment – Brachyspira spp.
            23000         Cultural enrichment - Campylobacter spp.
            16350         Cultural enrichment - Clostridium spp.
            19690         Cultural enrichment - Mycoplasma spp.
            18480         Selective cultivation of fungi (without species differentiation)
            12190         Cultivation Salmonella spp. (acc. ISO 6579)
            12720         Cultivation Salmonella spp. 5-fold passaging (in-house method)
            23010         Salmonella spp. - serovar-typing according to Kauffmann-White scheme
            18270
                          Salmonella Enteritidis Vaccine/Field strain-differentiation (Erythromycin/Rifampicin-
                          Sensitivity testing (LAH) and IDT Salmonella Diagnostics)
            18270
                          Salmonella Typhimurium Vaccine/Field strain-differentiation (Erythromycin/Rifampicin-
                          Sensitivity testing (LAH) and IDT Salmonella Diagnostics)
            13040         Serotyping (slide agglutination) E. coli
            13020         Serotyping (agarose gel precipitation) ORT
            10096         Serotyping (acc. to Heddleston) Pasteurella multocida
            13030         Serotyping (slide agglutination) Riemerella anatipestifer
                    $includes cultural examination for Salmonella spp. and basic bacteriological examination (price excl. further examinations,
                    such as resistance testing etc.)

                              1,2,3,4:   For explanation and comments see page 9

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                      Diagnostic Service Portfolio Poultry                                       Page 4 of 9
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DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No       Viral PCR1 & Sequencing
            17720         Avian Encephalomyelitis Virus (AEV)
            12300         Avian Influenzavirus Type A (“Matrix-PCR”, AIV)
            16690         Influenza H3
            13780         Influenza H5 & N1 combination
            14650         AIV, H5N1 + H7 combination
            16690         Influenza H6
            13880         Influenza H7
            16690         Influenza H9
            10149         Influenza-N-type determination N1 to N9 (price per each additional N-antigen)
            16690         Influenza-H-type determination H1 to H16 (price per each additional H-antigen)
            24740         Influenza H5/H7 sequencing for HPAI/LPAI differentiation
            19570         Avian Hepevirus (aHEV/ Avian Hepatitis E virus/ BLSD virus)
            12650         Avian Metapneumovirus A & B (serotype-specific, aMPV-A & -B / ART / TRT / SHS)
            14670         Avian Metapneumovirus C & D (serotype-specific, aMPV -C & -D)
            14660         Avian Metapneumovirus A to D (serotype-specific, combination)
            20770         Avian Nephritis Virus 1 & 2 (ANV-1 & -2)
            20720         Avian Nephritis Virus 3 (ANV-3)
            17740         Avian Ortho-Reovirus (ARV)2
            24700         Avian Ortho-Reovirus sequencing & phylogenetic analysis (C- and/or NS-gene)
            17740         Avian Ortho-Reovirus S1133 DIVA3-PCR
            22310         Avian Polyomavirus (GHPV / Hemorrhagic Nephritis and Enteritis Virus of Geese / HNEG)
            17800         Avian Rotavirus A & D (serotype-specific, combination)
            19850         Pheasant Rotavirus
            10356         Pigeon Rotavirus
            20290         Chicken Anemia Virus (CAV)
            20510         Chicken Astrovirus (CAstV, group A & B)
            10124         Chicken Astrovirus sequencing for differentiation of group A & B
            28500         Chicken Proventricular Necrosis Virus (Transmissible Viral Proventriculitis / CPNV / TVP)
            19770         Duck / Goose Reovirus (DRV / GRV)
            17820         Duck / Goose Circovirus (DuCV / GoCV; species-specific)
            16790         Duck Egg Drop Flavivirus (BYDV / Baiyangdian)
            16510         Duck Enteritis Virus (Duck plague, DEV)
            16500         Duck Hepatitis A Virus Type 1 (DHAV-1 / DHV-1)

                      1,2,3,4:   For explanation and comments see page 9

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                 Diagnostic Service Portfolio Poultry                                            Page 5 of 9
G.2.01, 2021.01.06 | Rev007
DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No       Viral PCR1 & Sequencing (continuing)
            20010         Muscovy Duck Parvovirus & Goose Parvovirus (MDPV, GPV) Screening-PCR
            22290         MDPV/GPV Typing-PCR for differentiation of Goose Parvovirus/Muscovy Duck Parvovirus
            10182         Duck & Goose Parvovirus DIVA³-PCR (Hoekstra)
            17770         Egg Drop Syndrome-76-Virus (EDS-76 / DuAdV)
            17780         Fowl Adenovirus (FAdV)2
            24720         Fowl Adenovirus sequencing for species and serotype determination
            23900         Fowlpox Virus (FPV)
            13960         Infectious Bronchitis Virus (IBV) / Avian Coronavirus (ACoV) screening (incl. IBV & TuCV)
            18700         IBV-variant-specific determination (package of all available variants)4
            24680         IBV sequencing & phylogenetic analysis (S1)
            16250         Infectious Laryngotracheitis Virus (ILTV)
            15760         IBDV screening incl. patho-typing (Gumboro, differentiation between vvIBDV and non-vvIBDV)
            24690         IBDV sequencing & phylogenetic analysis (VP1 & 2)
            27500               IBDV conceptual translation (12 amino acids)
            27510               IBDV conceptual translation (28 amino acids)
            28640         Innovax®-ND-IBD DIVA3-PCR
            19650         Herpes Virus of Turkeys (GaHV-3, HVT)
            19180         Marek's Disease Virus (MDV, GaHV-1)
            23820         Marek & Rispens DIVA3-PCR (separate detection of non-Rispens and Rispens strain)
            10119         Marek's Disease Virus sequencing
            20500         Newcastle Disease Virus (Avian Paramyxovirus-1, aPMV-1)
            24710         Newcastle Disease Virus / aPMV-1 patho-typing-PCR (lentogenic vs. meso- & velogenic)
            24710
                          Newcastle Disease Virus / aPMV-1 sequencing & patho-typing (assortment to lento-, meso- or
                          velogenic)
            19670         Reticuloendotheliosis Virus (REV)
            20000         Turkey Astrovirus 1 / 2 (serotype-specific, TAstV-1/-2)
            19630         Turkey Coronavirus (TuCV)
            18730         Turkey Hemorrhagic Enteritis (TuHEV)
            16970         Turkey Viral Hepatitis (TVH)
            29390         Vaxxitek® HVT+IBD DIVA3-PCR
            10101         Vectormune® ND DIVA3-PCR

                      1,2,3,4:   For explanation and comments see page 9

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                 Diagnostic Service Portfolio Poultry                                            Page 6 of 9
G.2.01, 2021.01.06 | Rev007
DIAGNOSTIC SERVICE PORTFOLIO - ANICON LABOR GMBH
Item-No       PCR1 and Sequencing - Mycoplasma
            14640         Mollicutes spp.
            12450         Mycoplasma gallisepticum (Mg)
            14710         Mg DIVA3-PCR vaccine strain 6/85-like and F-like-strain
            23740         Mg DIVA3-PCR vaccine strain ts-11
            19190         Mycoplasma iowae (Mi)
            19130         Mycoplasma meleagridis (Mm)
            13050         Mycoplasma synoviae (Ms)
            19290         Ms-H DIVA3-PCR (incl. Ms field strain detection)
            22430         Ms-1 DIVA3-PCR
            12440         Mg & Ms (species-specific, combination)

            Item-No       PCR1 and Sequencing - Chlamydia
            19840         Chlamydia spp. screening, C. abortus & C. psittaci (species-specific, combination)
            14020         Chlamydia spp. screening
            19680         Chlamydia abortus
            19780         Chlamydia avium (doves, psittacidae)
            19790         Chlamydia gallinacea
            10088         Chlamydia gallinacea

            Item-No       PCR1 and Sequencing - Diverse
            14540         Avibacterium paragallinarum (Infectious Coryza)
            18870         Bordetella avium
            21530         Brachyspira spp.-screening
            10311         Brachyspira hyodysenteriae, B. pilosicoli (species-specific, combination)
            10333         Brachyspira intermedia
            27520         Cryptosporidium parvum
            14610
                          Thermophilic Campylobacter spp. (incl. C. coli, C. jejuni, C. lari, C. upsaliensis;
                          excl. C. hepaticus)
            10086         Campylobacter coli, C. jejuni, C. lari (species-specific, combination)
            10087         Campylobacter hepaticus
            14550         Clostridium perfringens major & minor toxin genes#
            14630         Erysipelothrix rhusiopathiae (Erysipelas)
                    #   The following toxin genes are analysed: major toxin genes alpha, beta, epsilon & iota and minor toxin genes beta2, enterotoxin
                        & netB

                        1,2,3,4:   For explanation and comments see page 9

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                   Diagnostic Service Portfolio Poultry                                          Page 7 of 9
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Item-No         PCR1 and Sequencing – Diverse (continuing)
              10355           Escherichia coli
              14700           E. coli 8 x APEC (virulence genes factors; incl. F11-antigen)
              10282           E. coli 15-fach APEC (virulence genes factors; incl. F11-antigen)
              15680           Histomonas meleagridis
              10228           Lawsonia intracellularis
              13800           Ornithobacterium rhinotracheale (ORT)
              17590           Pasteurella multocida
              24370           Pasteurella multocida subsp. septica
              14680           Pasteurella multocida capsule typing
              13430           Riemerella anatipestifer
              22460           Salmonella spp.
              24110
                              SGP DIVA3-PCR (serovar-specific differentiation of Salmonella Gallinarum and Pullorum
                              and vaccine strain 9R specific)
              19370
                              SE DIVA3-PCR (Salmonella Enteritidis serovar-specific & vaccine strains IDT/CEVA and
                              LAH/ELANCO specific) combined with ST (Salmonella Typhimurium serovar-specific)
              22540           Staphylococcus aureus
                    #   The following toxin genes are analysed: major toxin genes alpha, beta, epsilon & iota and minor toxin genes beta2, enterotoxin
                        & netB.

              Item-No         Respiratory Pathogens - Scaffold Pricing of Packages*
              20810           PCR-package of 2 respiratory pathogens (bact. / viral)*
              20820           PCR-package of 3 respiratory pathogens (bact. / viral)*
              20830           PCR-package of 4 respiratory pathogens (bact. / viral)*
              20840           PCR-package of 5 respiratory pathogens (bact. / viral)*
              20850           PCR-package of 6 respiratory pathogens (bact. / viral)*
              22370           PCR-package of 7 respiratory pathogens (bact. / viral)*
              22380           PCR-package of 8 respiratory pathogens (bact. / viral)*
              22390           PCR-package of 9 respiratory pathogens (bact. / viral)*
                    * does not apply for DIVA 3-PCRs, typing-PCRs or other PCR-packages and sequencing

                        1,2,3,4:   For explanation and comments see page 9

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                                   Diagnostic Service Portfolio Poultry                                          Page 8 of 9
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Item-No       Cultural Virus Isolation
            17700         Virus cultivation in cell culture / in embryonated egg (excl. PCR for confirmation)
            14030         Archival storage (bacterial & viral strains)
            19980         Combination FAdV & ARV: culture & PCR

             Explanation and comments:
             1   Samples of up to five individuals can be pooled. It is crucial to indicate when sending several swabs whether these are already
                 pooled or need to be pooled. Please find respective submission forms on www.anicon.eu → downloads.

             2   Direct diagnostics of Fowl Adenovirus (FAdV) and/ or Avian Ortho-Reovirus (ARV) from raw samples by PCR methods
                 may lead to false negative results; we run at least three passages of virus cultivation before confirmation by PCR methods in
                 harvested cultural material, if not explicitly ordered for PCR only. Please see also article „combination FAdV & ARV:
                 culture and PCR“ in chapter virology.

             3   DIVA - Differentiating Infected from Vaccinated Animals - method for differentiation of field strains from named vaccine strains.

             4   793B (4/91, CR88); QX (D388); D1466; Massachusetts; D274; Italy 02; Arkansas; Variant 2 (Israel 02/IS1494); Q1; IB80; D181

All prices are exclusive value-added tax. – Our general terms and conditions apply, available on www.anicon.eu. Hoeltinghausen, 01.06.2021
                                              Diagnostic Service Portfolio Poultry                                               Page 9 of 9
G.2.01, 2021.01.06 | Rev007
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