The Double Standards of Cannabis and Nicotine - By Michelle Minton September 2020
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The Double Standards of Cannabis and Nicotine By Michelle Minton September 2020 ISSUE ANALYSIS 2020 NO. 7
The Double Standards of Cannabis and Nicotine By Michelle Minton Executive Summary Though different in nature and purpose, the scientific The principal benefit of recreational cannabis, as the evidence on cannabis and nicotine is remarkably name implies, is recreation. Many who enjoy using similar, in terms of the risks they might pose. Decades the substance do so solely because of the pleasure they of research and popular use confirm that the harms derive from it. Nicotine vapor products or “e-cigarettes” associated with regular cannabis use are, for most are not only a source of pleasure, but also a critical people, relatively minimal, even if some questions tool that has helped millions of adults kick their remain, such as, for example, on how it interacts with deadly smoking habit. Yet, at the same time that certain medications and psychiatric conditions or how public and political support for legalizing recreational it might impact adolescent development. cannabis has soared, so also have calls to virtually More importantly, history provides compelling evidence eliminate or prohibit legal access to potentially that whatever hazards might be associated with life-saving nicotine vapor products. cannabis, they are preferable to those created by its Since e-cigarettes first entered the U.S. market around prohibition. The federal ban on cannabis did little to 2007, anti-smoking advocates have voiced concern stop its widespread use. As with alcohol before it, about their possible hazards and demanded that prohibiting cannabis spawned a sophisticated government restrict their availability. That stance might illicit market, incited contempt for the law, cost the have seemed reasonable in the beginning, since, as economy billions of dollars, fomented distrust of law opponents argued, research on the products and their enforcement, and ruined countless lives. Thus, with potential health effects was limited. It also implied research unable to identify any meaningful harms that detractors would withdraw, or at least temper, caused by cannabis use and witnessing the damage their opposition to the sale of e-cigarettes should caused by its prohibition, the general consensus is that sufficient evidence reasonably establish their relative our society would be healthier, freer, and more just by safety. restoring adults’ ability to use cannabis legally. The evidence has emerged that e-cigarettes are vastly Like cannabis, many unknowns remain about the safer than smoking, even if not risk-free, and have the effects of nicotine and nicotine vaping, but there is potential to save or improve millions of lives. Yet, enough to know its risks are minimal and are anti-vaping advocates’ hostility toward e-cigarettes has substantially lower than for combustible tobacco. We only intensified and governments around the world have also know that nicotine vapor products help adult begun banning the products. The reason, as this paper smokers quit smoking, providing an immediate public demonstrates, is that regulation of certain controversial health benefit by diverting smokers to less harmful substances often has little to do with evidence. As the alternatives. Banning e-cigarettes will not stop people comparison of the evidence on and debate over nicotine from using them, but like every prohibition before it, and cannabis reveal, the way some activists and policy push many toward more hazardous behaviors, such as makers treat controversal substances depends less on buying from the illicit market or continuing to smoke. science and evidence than on the prevailing narrative Yet, restrictions and bans on e-cigarettes continue to they choose to believe and promote. sweep across the nation. Minton: The Double Standards of Cannabis and Nicotine 1
This different treatment of two relatively analogous Decades of promoting hostility toward “Big Tobacco” substances cannot be explained by the scientific proved helpful for this effort. Like tobacco companies evidence. It arises from what the public and, in that once sought to deceive the public about the risks particular, those in power choose to accept as evidence of smoking, anti-vaping activists waged a campaign to and the popular narrative this creates. Popular culture, sow doubt about the safety of e-cigarettes. With billions the media, reform advocates, and individual users in public funding, an army of affiliated academics, coalesced around a consensus that many adults enjoy allies in government and media, and the support of cannabis and will continue to do so regardless of its industries threatened by new competition, activists legality. The general public now overwhelmingly generated a steady stream of negative headlines about believes that cannabis use is inevitable, prohibition is “vaping.” futile, and adults should have the right to use it simply They knew from their fight with Big Tobacco that they because they enjoy it. But the same does not apply for could persuade the public of the need for government nicotine. intervention if they believed that a choice posed risks, For a long time, the narrative surrounding nicotine not just to the individual making it, but to those vapor has been one of fear and suspicion. It has around him. So, as with secondhand smoke and youth increasingly focused on unknown risks and the threat smoking, anti-vaping advocacy focused on the threat e-cigarettes might pose to adolescents, even as the e-cigarettes supposedly posed to adolescents and to scientific evidence consistently shows these fears are public health. overstated, and demonstrates the products’ safety and The strategy has been wildly successful. While the benefits for adults. This was no accident. evidence continues to mount in favor of e-cigarettes’ Prior to the advent of e-cigarettes, declining smoking effectiveness for smoking cessation, public opinion is rates posed an existential threat to anti-tobacco increasingly in favor of banning the products. Even as activists and groups. As smoking declined in America embraces an approach aimed at reducing the popularity, those who had built careers and harms of risky behavior with policies like clean needle organizations in the well-funded battle against exchanges, sexual education, and cannabis legalization, smoking found themselves victims of their own we are turning more toward a zero-tolerance approach success. E-cigarettes provided the perfect bogeyman when it comes to nicotine. Unfortunately, that is to stoke public anxiety and revive fundraising. Thus, because evidence is not the driving factor in the anti-tobacco activists redirected their efforts toward political debate over substance use. turning public opinion against these novel products. 2 Minton: The Double Standards of Cannabis and Nicotine
Introduction American adults said they currently A large proportion of nicotine vapor used marijuana, with 35 percent using users credit the products with saving it regularly.1 In contrast, nicotine use their lives, a claim rarely—if ever— in the U.S. is at a historic low, with made by those who use cannabis purely under 14 percent of adults categorized The case for for recreation. Yet, while legalizing as current smokers and only 8 percent recreational cannabis is now a cause of adults saying they vaped within the legalizing célèbre among liberal and some past week as of 2019.2 cannabis conservative politicians, a prohibition on nicotine vapor products—sometimes Public opinion, among users and is strong. non-users alike, has evolved alongside referred to as electronic cigarettes— these consumption patterns. A Gallup has become an equally fashionable poll in 2019 found that 66 percent of position, often among the same the American public supported individuals. legalizing marijuana.3 The same year, a Advocates of greater restrictions or poll by the Kaiser Family Foundation bans on nicotine vaping cite a lack of found that a majority (52 percent) of evidence on the effects of vaping. That Americans favored banning all but seems to imply that their position might tobacco-flavored e-cigarettes, while change if the products’ safety and nearly half (49 percent) favored a total efficacy were ever proved by research, ban on nicotine vaping products.4 But but it has become clear that such a this evolution in opinion, among both prospect is just a political smokescreen. the public and politicians, is not based As the divergent treatment of cannabis on conclusive scientific evidence. and nicotine demonstrates, when it After decades of research, there is comes to the regulation of substances, enough evidence to assume that the neither evidence, principles, nor even health effects of cannabis use are justice actually matter. All that matters unlikely to be life-threatening. For at is the popularity of the given narrative least 20 years of study and public about a substance. debate, the case for legalizing Cannabis and nicotine are both cannabis—in terms of public safety, as pleasurable substances that have well as social, economic, and personal enjoyed widespread popularity for well-being—is strong. This evidence, hundreds of years. Both have a large along with efforts by activists and body of scientific research, as well as health professionals to destigmatize many unanswered questions, about the drug and its users, largely explain their effects on human health. Yet, in why the public and subsequently recent years cannabis has become far lawmakers have begun to look more more popular. In 2017, 55 percent of favorably on legalizing cannabis. Minton: The Double Standards of Cannabis and Nicotine 3
However, the scientific evidence on the law. And, of course, the rise of the the health effects of cannabis has illicit market, with its outsized profits, remained largely inconclusive.5 draws many people into risky or Hampered by regulatory barriers, criminal behavior, with often terrible The costs of researchers have been able to shed consequences both for the individuals light on some aspects of the drug’s engaging in illicit activities and their prohibition on impact on health, but major questions communities. individuals, remain unanswered.6 For example, By weighing what we do know about there is very limited data on how society, and tetrahydrocannabinol (THC) affects the health effects of cannabis against the known consequences of prohibition, the economy heart health.7 We are just beginning America has come to the reasonable to understand how different patterns have proven of use may interact—either positively conclusion that whatever risks might ultimately be associated with cannabis catastrophic. or negatively—with other physical use, they are lesser than, or preferable and psychological conditions, to, the harms created by its prohibition. predispositions, and treatments.8 Furthermore, little is known about how cannabis alters brain function in adults Regulation in the Face and brain development in adolescents.9 of Uncertainty On the other hand, the costs of In the absence of complete and perfect prohibition on individuals, society, and scientific information—something the economy have proven catastrophic. almost no topic enjoys—regulators For the last half century, Americans must carefully weigh the strength of have observed the utter failure of the evidence we do have about the banning cannabis to stop its widespread potential harms and benefits of giving use; how it spawned sophisticated, consumers legal access to substances international drug-trafficking networks; against the likely harms and benefits cost our economy billions; fomented of prohibiting that substance. With distrust between the citizenry and law regard to cannabis, regulators, enforcement; and ruined untold researchers, and the general public, for numbers of lives.10 Outlawing the drug the most part, have rightly come to the did not stop demand. Instead, it drove conclusion that the costs of prohibition millions into the illicit market, where, far outweigh the potential risks in addition to any risks inherent to the associated with legal access to the drug. drug, they are exposed to the additional Were regulators and lawmakers to hazards of interacting with criminals, objectively perform this sort of potentially consuming adulterated or calculation for nicotine, they would tainted products, and running afoul of 4 Minton: The Double Standards of Cannabis and Nicotine
conclude the same for that substance. As with recreational cannabis, the While it is true that, as with clinical evidence indicates that the recreational cannabis, we may not health effects of nicotine vaping are fully understand all of the effects of minimal—at least minimal enough nicotine vaping, there is enough that researchers have been unable to As with evidence to conclude that the effects consistently demonstrate any negative on health are limited to the degree that effects at all. This is why nicotine recreational a regulatory scheme that maintains replacement therapy, for example, is cannabis, legal access to these products will be not associated with increased risk of less detrimental to individual and cancer, cardiovascular disease, stroke, the clinical public health than a prohibition on or other diseases commonly linked evidence such products. with smoking.12 Furthermore, the benefits to society of providing access indicates that Nicotine vaping devices are a relatively new category of products, to smokeless nicotine has been the health validated by studying the experiences but tobacco and nicotine use, in of countries that have embraced lower effects of various forms, is not. Though public health professionals have historically risk tobacco alternatives, like Sweden. nicotine conflated the effects of smoking and Snus, a moist tobacco chew, has been vaping are nicotine, the advent of nicotine vaping, in use in Sweden since the 17 century, th which separates the effects of nicotine but it gained in popularity beginning minimal. from combustion, has become the in the 1980s as the dangers of smoking subject of intense scientific study over became clearer and more well known. the last 15 years. Because of public By 2016, approximately 21 percent of interest and the lack of regulatory Swedish men were classified as current barriers on its study, current clinical snus users, while just 7 percent of the data on nicotine is as robust as that for population continued to smoke, and recreational cannabis, if not more so. just 5 percent smoked daily.13 As a We have more than 400 years of result of replacing a combustible observation about non-combustible tobacco with a non-combustible tobacco use, such as tobacco chew, product, Sweden has not only the snuff, and snus (moist snuff).11 There lowest smoking rate in Europe, but is also plenty of information available also the lowest rate of lung cancer— on the social and economic effects by far—and among the lowest rates of various regulatory schemes for of mouth cancer.14 In the rest of the nicotine products, based on experiences European Union, where snus is in the U.S. and around the world. banned, 24 percent of the population, on average, smoked as of 2016.15 Minton: The Double Standards of Cannabis and Nicotine 5
Similar effects have been observed in their stoner comedy films, beginning Japan, where the rate of decline in with the 1978 cult classic Up in Smoke. cigarette sales has quintupled since And beginning in the 1970s, hip hop the introduction of Philip Morris and rap artists used marijuana in their Government International’s heated tobacco product, lyrics (and lives) as a form of rebellion IQOS.16 Great Britain and the United against and rejection of a mainstream policies that States, where the government embraces society they believe marginalizes seek to restrict or tolerates e-cigarettes, respectively, individuals and communities of color.20 have seen similar accelerations in the By the 1990s rap and the stoner legal access decline of smoking.17 comedy had been incorporated, at to nicotine do More importantly, perhaps, evidence least in some forms, into popular mass media. It was this “mainstreaming” of not prevent from around the world demonstrates art forms with positive and often that government policies that seek to nicotine use. restrict legal access to nicotine, celebratory representations of cannabis use, more than any scientific break- whether through regulatory barriers, through, that acted to destigmatize the bans, or price controls, do not prevent drug, change popular opinion, and nicotine use. Instead, illicit markets, pave the way for legalization.21 and all of the harms that accompany them, rise to meet the demand.18 Though different in their chemical makeup, biological effects, and The ability and willingness of the purpose, the scientific literature on public to flout restrictive drug laws recreational cannabis and nicotine are has been on display in the United remarkably analogous. Current clinical States and elsewhere with regard to data suggests both substances are cannabis. Not only did Americans relatively safe, emerging evidence continue to use the substance after its even points to potential health benefits ban, but some made ostentatious for both, and plenty of research displays out of flouting the prohibition. demonstrates the harms associated Cannabis was popular among jazz with the prohibition of either. Nicotine musicians during the first half of the vapor products have the additional 20th century, a fact not lost on benefit of typically being used, prohibitionists of that era, who not just for enjoyment, but as a pursued famous musicians, like Louie replacement for deadly combustible Armstrong and Billie Holiday.19 tobacco products, like cigarettes. Yet, And long before the first U.S. state one of these drugs—cannabis—enjoys legalized its use, the comedy duo increasing popular and political Cheech and Chong arguably support and decreased stigmatization, established a new genre of cinema with 6 Minton: The Double Standards of Cannabis and Nicotine
while the other—nicotine—is of vaping, this evidence is available. progressively maligned, stigmatized, Toxicology studies show that even the and the target of bans and restrictions. earliest e-cigarette devices on the market contained only a fraction of the This asymmetry in the treatment of the two substances cannot be explained by harmful and potentially harmful As with constituents found in traditional the amount or strength of the scientific cigarettes.24 Studies also show that cannabis, evidence for their relative benefits or harms. Instead, it stems from what exhaled vapor contains 99 percent evidence has fewer carcinogens than secondhand those in power are willing to accept as smoke.25 Epidemiological studies have disproved evidence.22 The notion that people enjoy using cannabis and will continue to do repeatedly found that the vast majority the claim of those using nicotine vapor products so regardless of its legal status is now are former smokers.26 that nicotine widely accepted. The inevitability of widespread cannabis use and the As with cannabis, evidence has also vaping is a futility and harm of its continued disproved the claim that nicotine “gateway” to prohibition are sufficient justification vaping is a “gateway” to more harmful to advocate for an end of the federal substances, in this case smoking more harmful cannabis ban. That logic, though combustible tobacco.27 Perhaps the substances, demonstrably true for both cannabis most convincing evidence against the and nicotine, has proved insufficient idea that vaping leads to smoking is in this case to convince advocates, regulators, that, even as youth experimentation smoking and even some researchers. Unlike with vaping has risen significantly over recreational cannabis, for nicotine the 13 years since its introduction, combustible vapor they demand “proof” of the youth and adult smoking have tobacco. products’ value before they are continued to decrease. Studies, allowed onto the market.23 Yet, it including one randomized clinical trial remains unclear what type of—and (considered by some to be the gold how much—evidence it would take to standard in health research), have even meet their threshold of proof. demonstrated that nicotine vapor products are two to three times more effective at helping smokers quit than Drug Double Standard other nicotine replacement therapies It is reasonable for public health (NRT).28 professionals, lawmakers, and the Each of the aforementioned studies, public to want evidence about products along with any before or since showing prior to making decisions about how similar findings, were, without they ought to be regulated. In the case exception, rejected by the individuals Minton: The Double Standards of Cannabis and Nicotine 7
and groups demanding proof of the and questions the researchers did not value of nicotine vapor products. As seek to answer. Clive Bates, the former director of the Dozens of observational studies are British tobacco control group Action often dismissed as being merely based on Smoking and Health, wrote in on anecdotes. Those dismissals are 2018, the justifications provided by often accompanied by calls for anti-vaping advocates for spurning randomized controlled trials, which these studies follow an almost could really prove whether nicotine comically predictable pattern. vapor products are effective as Harm is the essential currency of cessation tools.30 When researchers tobacco control campaigning. For performed a randomized controlled these activists, cancer and other trial and found that e-cigarettes were harms have acquired valuable twice as effective as other nicotine utility: it is the “killer” arguments replacement therapies for smoking to justify the forceful action of the cessation, anti-vaping interests state. If there is no cancer or other dismissed it as being too clinical and harms, they have lost an argument “not a study of e-cigarettes as most to support the real goal. Hence, people use them.”31 we see desperate, often risible, The most consistently employed efforts to turn nugatory risks into argument against studies showing few full-blown moral panics. If or no negative health effects related to concerned about health, why nicotine vapor is that they are not do they never talk about how conducted over a long enough period e-cigarette vapour has few of the of time to reveal the harms from harmful agents present in chronic use of the products over cigarette smoke and those that are decades. When supplied with research present at far lower concentrations? that follows participants for years— Because disease risk creates the which would be able to identify bio- currency of fear and righteous logical changes related to long-term indignation, and fear and health—anti-tobacco activists simply indignation is the gateway to return to the other tactical arguments. regulation.29 [Emphases in original] For example, in 2017 researchers published the results of a study Typically, critics of nicotine vaping comparing circulating levels of respond to studies with results they smoking-related toxins linked to dislike by quibbling over flaws in the cancer, heart disease, and lung disease methodology, the length of the study, among long-term smokers, e-cigarette 8 Minton: The Double Standards of Cannabis and Nicotine
users, users of nicotine replacement smoking.” The study did not, and therapies, and “dual” users—those could not by design, determine the who both smoke and use NRT or prevalence of dual use in the population e-cigarettes. While dual users in any because the researchers recruited combination had similar levels of equal numbers of participants for each Even if it were harmful toxins to that of smokers, group studied. More importantly, even individuals using e-cigarettes if it were true that many e-cigarette true that many exclusively for six months or more users continue to smoke, that, along e-cigarette users had similarly low or significantly with the results of this study, in no way lower levels of circulating toxins than supports the claim that e-cigarettes continue to exclusive NRT users.32 Rather than have “no health benefits” for smokers. smoke, that in celebrate this as evidence that long-term In the real world, the study’s ground- e-cigarette use is, at the very least, no breaking finding, that the harms of no way supports more harmful than long-term NRT long-term e-cigarette use are as low the claim that use—a practice widely encouraged by and possibly lower than long-term anti-tobacco advocates— vaping NRT use, is compelling evidence that e-cigarettes have opponents focused on the finding that researchers and activists, like Glantz, “no health e-cigarette users who also smoked had should figure out how to encourage toxin levels similar to smokers, an smokers to switch to e-cigarettes benefits” for unsurprising result that is largely, if not exclusively. Indeed, this was smokers. entirely, explained by their smoking. suggested by the study’s authors, who wrote that their finding of similar “Everyone—including me—agrees nicotine intake levels among smokers, that switching entirely from cigarettes exclusive NRT users, and exclusive to e-cigarettes (assuming no effects on e-cigarette users “supports the view cessation) would be a good thing,” that users seek a particular level of wrote Stanton Glantz, a longtime nicotine intake, regardless of the anti-tobacco activist and professor at delivery system.” Thus, they the University of California, San concluded that “dual users should Francisco.33 “The problem is, as this be encouraged to cease using paper notes, that almost all e-cigarette combustible products to reduce users keep smoking cigarettes … for long-term health risks.”35 the great majority of e-cigarette users as they are actually used in the real The argument made by Glantz provides world, there is no health benefit of a good example of the double standard e-cigarettes” he continued.34 of proof applied to nicotine vapor [Emphasis in original] products. Based solely on the unsupported idea that most e-cigarette Glantz is incorrect that the study found users continue to smoke, Glantz is “almost all e-cigarette users keep Minton: The Double Standards of Cannabis and Nicotine 9
willing to dismiss the possibility that amount of time to understand the nicotine vapor products have any effects of nicotine vaping. That is a benefit and to advocate for their total disingenuous argument, given that prohibition.36 Interestingly, Glantz research on smoking began in the For almost every omits from this conversation the 1940s when science on the topic evidence that continued smoking by was nascent. other aspect users of nicotine replacement therapies It certainly would be nice to have of human life, is also extremely common. According multidecade studies on every possible to some estimates, as little as 1 or 2 we recognize percent of NRT users even attempt to consequence of a product prior to its introduction on the market. But that the reality that achieve abstinence from smoking, criterion is as impractical as it is while a higher percentage intend proof of total merely to reduce their cigarette unnecessary. Virtually nothing in life is free of risk entirely. As Fred Smith, safety is consumption.37 However, studies have the founder of the Competitive found that smokers who use NRTs unrealistic. actually smoke more cigarettes than Enterprise Institute, once remarked, if “society demands unattainable levels smokers not using such products.38 of safety—a risk-free world—public This real world experience with NRTs policy becomes divorced from has not led anti-tobacco activists to reality.”42 For almost every other aspect call for banning the products.39 In fact, of human life, we recognize the reality some of the most vociferously that proof of total safety is unrealistic. anti-vaping entities, like the Campaign Moreover, we inherently grasp that for Tobacco-Free Kids, not only applying such a standard would support over-the-counter sales of NRT produce economic, technological, and products, but advocate for governments personal paralysis. But, when it comes to subsidize their provision to adult to lower-risk means of nicotine smokers.40 consumption, that is the standard that Criticisms of the evidence that activists demand, despite the potential nicotine vaping is relatively harmless of such products to save and improve or even beneficial are often joined millions of lives around the world. with statements about the lack of There are already hundreds, if not long-term evidence and how many thousands, of studies on nicotine decades it took researchers to vaping, including on animals and demonstrate the devastating harms humans, observational and clinical, associated with smoking.41 This and short- and long-term.43 These implies that it would take modern studies, while not answering every researchers, despite all the advances in possible question that might arise science and technology, a similar surrounding nicotine vapor, are enough 10 Minton: The Double Standards of Cannabis and Nicotine
for researchers to measure biological even less study, such as the ultra-low- changes that would indicate long-term nicotine cigarettes approved by the risk. Thus far, the research does not FDA in December 2019, for which the indicate any significant long-term longest studies were a mere 20 weeks, harms, particularly for those who are with many questions remaining about The standard using nicotine vaping to replace the whether smokers using low nicotine far more harmful habit of smoking. cigarettes will actually smoke more.48 of evidence that The standard of evidence that anti- As for cannabis, only a single product anti-tobacco has been approved by the FDA. In this tobacco activists demand for nicotine case, studies of the CBD medication activists demand vaping is not applied to any other category of consumer good. For intended to treat seizure disorders for nicotine lasted less than a year.49 No other instance, a lack of decades-long cannabis products sold in the U.S., with vaping is not studies that might definitively and comprehensively reveal all possible or without THC, have undergone such applied to a review. Yet, the lack of certainty about risks has not stopped the introduction how cannabis affects adolescent brain any other of new pharmaceutical drugs.44 Although the entire approval process development, an issue on which category of anti-vaping advocates seem singularly is arduous and lengthy, lasting focused when it comes to nicotine, consumer upwards of a decade or longer, the duration of individual trials, which has not stopped the growing—and good. justified—push for cannabis form the evidence for a new drug’s legalization.50 safety and efficacy, can last for just one year.45 Even for many drugs intended The American Lung Association to be taken regularly over a period of (ALA), for example, has been vocally many years, like antidepressants and opposed to nicotine vapor products cholesterol-lowering statins, long-term and has lobbied state and federal studies are not required prior to their governments to institute bans and introduction to the market, so long restrictions against their sale and as there are at least two positive advertising.51 With regard to cannabis, short-term (eight- to 12-week) trials.46 the ALA once was a vocal opponent of the drug’s use, claimed that “marijuana For example, in March 2019, the U.S. deposits four times more tar in the lungs Food and Drug Administration (FDA) than tobacco,” and ran a campaign in approved Spravato, a nasal spray the 1980s titled, “Don’t Let Your antidepressant chemically related to the Lungs Go to Pot.”52 Today, however, drug ketamine. This approval occurred apart from advocating that cannabis be even though the longest trial of the included in indoor smoking bans, the drug was no more than 60 weeks.47 ALA is conspicuously silent on the Non-pharmaceutical products require Minton: The Double Standards of Cannabis and Nicotine 11
issue of cannabis legalization and Moral Entrepreneurs regulation.53 At the heart of the modern tobacco control movement are what sociologist As with cannabis, a lack of definitive Howard S. Becker calls “moral evidence has neither stopped the A lack of government from approving, nor entrepreneurs.”54 These professional arbiters of morality or rule makers definitive society from accepting, a range of typically begin as passionate amateurs, other products, medications, and evidence has devices. That is as it should be. often with humanitarian motives. They do not simply want to impose their neither stopped Long-term studies that unequivocally moral views on others, but operate tell us, for example, how cannabis the government would affect every aspect of individual from the belief that doing so will improve the well-being of society. from approving, and social welfare are not only This ostensibly pure intention impossible for each facet of the drug’s nor society from development and deployment, they are provides justification for moral crusaders to pursue their goals by any accepting, a also unnecessary. We now have enough means necessary, including working information to know that whatever range of other harms may be associated with cannabis with those with dubious motives, exaggeration, defamation of the products, use, they are minimal in comparison to opposition, disregarding others’ the harms created by prohibition. The medications, same is true of nicotine and nicotine autonomy, and persecuting those who disobey—for their own good, of course. and devices. vapor products. Yet, when it comes to nicotine vaping, the evidence doesn’t The crusader who manages to That is as it seem to matter. The constant appeals convince the public of the validity of should be. for proof and the way substances are his cause may be able to build large treated by lawmakers, regulators, organizational structures around it and the media, and the public are not turn his passion into a vocation. But determined by scientific evidence, but this presents a conundrum for the are based on how people feel about the crusader: If successful, he would substance. In the current moment, at essentially be putting himself out of a least, the majority of the public now job. Such was the case for the accepts cannabis use as a relatively enterprise of anti-smoking activism. harmless activity, akin to drinking After decades of raising awareness alcohol. Unfortunately, the way about its risks and convincing the most people feel about nicotine is public and government officials of the inextricably linked to their feelings need to control smoking, the habit was about “Big Tobacco.” headed toward extinction. By the 21st century, smoking had become a socially stigmatized, deviant behavior 12 Minton: The Double Standards of Cannabis and Nicotine
in many developed nations. Many clove cigarettes, and nicotine-free countries, particularly the U.S., had cigarettes fell flat.56 But then came also banned smoking in public spaces, electronic cigarettes. With a similar- imposed taxes on the products, and sounding name, look, and even adopted strict tobacco control policies. smoke-like plumes of vapor emitted The rise in from the devices, electronic cigarettes By the mid-2000s, precipitous declines popularity of proved the perfect new target for in smoking had diminished public moral entrepreneurs to continue their nicotine vaping concern over the habit’s health effects, crusade against Big Tobacco—even which in turn lessened interest in occurred at the if Big Tobacco, particularly in the funding cessation efforts. This waning beginning, had nothing to do with the same time as the attention threatened what had become novel products. a multi-billion-dollar anti-smoking anti-smoking industry and the thousands of agencies, activism industry departments, charities, and careers The “Big Tobacco” Bogeyman built around it. Rather than kill the was desperately With good reason, people maintain a anti-smoking cash cow, activists sought deep distrust of big tobacco companies, searching for to expand their crusade to new which historically had long denied the targets—not only smoking, but any a new target. deadly effects of combustible tobacco use of tobacco and, more recently, any of which they were aware, putting use of non-pharmaceutical nicotine. significant resources into casting doubt As Becker wrote, a moral crusader on and undermining evidence of those who manages to achieve his original harms as it emerged. However, this goal “may generalize his interest and understandable mistrust has been discover something new to view with extended, often intentionally, by alarm, a new evil about which anti-tobacco advocates, to any person, something ought to be done. He group, or industry that appears to be, becomes a professional discoverer or is accused of being, linked to big of wrongs to be righted, of situations tobacco companies. requiring new rules.”55 This near-universal contempt for Big The rise in popularity of nicotine Tobacco and the effectiveness of guilt vaping occurred, not coincidentally, by association with it is well-known at the same time as the anti-smoking among activists of all stripes. This activism industry was desperately explains the proliferation of accusations searching for a new target. Their of “stealing a page out of the Big attempts to foment renewed moral Tobacco playbook” hurled at various panic over products like flavored businesses and industries— including nicotine lozenges, bidis (mini cigars), food marketers, soda companies, the Minton: The Double Standards of Cannabis and Nicotine 13
alcohol industry, the tech industry, relative harmlessness or possible social media platforms, climate change benefits of the substance. skeptics, lawmakers, and even the Anti-tobacco groups have used this National Football League. 57 tactic to paint the nicotine vapor Those who oppose the use of nicotine industry as no different from Big on moral grounds have made little Tobacco. But this simplistic view attempt to hide their use of this tactic ignores the fact that while large as a way to discredit any person or tobacco companies have now entered study unsupportive of their abstinence- the nicotine vapor market, the industry only approach. In a 1986 handbook on was initially established and remains anti-tobacco activism, the authors— primarily populated by small, including the aforementioned Stanton independent vapor companies that Glantz—advised that inconvenient were never involved in the tobacco studies could be easily explained business. away by pointing to “the self-interest More importantly, it also fails to of the authors, defective methodology, acknowledge that the central reason or sheer weight of numbers of these independent vapor companies contradictory studies” and that and shops exist is to displace activists should “suggest that the combustible tobacco. Still, the mere person is simply a shill for the tobacco fact that the initial generations of industry.”58 A few years later, Glantz, nicotine vapor products looked similar in a speech, noted that a similar to cigarettes, were sometimes called approach could be used to convince electronic cigarettes, and contained reluctant lawmakers to support their nicotine despite not having any anti-tobacco policies, noting that a tobacco, was enough for activists to good way to change their minds is to convince the federal government to convince them that “if they oppose deem the products “tobacco” in 2016.60 you they would be perceived as dupes This bureaucratic categorization of of the cigarette companies.”59 nicotine vapor as tobacco product, As blatant and opportunistic as that plus the superficial similarities with is, the strategy continues to work traditional cigarettes, made it easy for effectively in convincing many that any activists to convince those unfamiliar nicotine product, not produced by “Big with the novel products that they were Pharma,” is merely an extension of the same as combustible tobacco, made “Big Tobacco.” That leaves them free by the same companies, with the same to disregard any evidence about the purpose and risks. (This is a little like 14 Minton: The Double Standards of Cannabis and Nicotine
viewing distilled spirits and rubbing In the case of nicotine vaping, alcohol in the same light.) evidence continues to mount that it is relatively harmless for adults. Even the assertion that nicotine is “highly Merchants of Doubt and Fear addictive,” something most people In the case Ironically, both the impossibly high believe is irrefutably true, is double standard for scientific evidence contradicted by evidence and logic. of nicotine and attempts to create a mental link People rarely become addicted to vaping, between nicotine vaping and Big nicotine patches, gums, or lozenges. Tobacco are exactly the same strategies Animal and human studies have found evidence used by Big Tobacco since the 1950s that nicotine alone is not sufficient to continues to to suppress growing evidence of the prompt self-administration or nicotine- harms associated with smoking.61 This seeking behavior—for instance, lab mount that awareness of Big Tobacco’s past bad mice do not press the lever delivering it is relatively behavior and the public’s distrust of nicotine over the lever that delivers the industry significantly increase the food. That suggests that is some other harmless potency of anti-tobacco activists’ chemical, combination of chemicals, for adults. primary argument against nicotine or feature of cigarettes that makes vaping: the safety of children. products containing nicotine habit- forming.63 “Won’t somebody think of the children” was the oft-repeated catchphrase of Unable to justify their opposition to Helen Lovejoy, wife of Reverend nicotine use based on demonstrable Lovejoy on the television comedy harms to adults, anti-tobacco activists The Simpsons. This parody of the instead have focused on the imaginary overwrought and myopic focus on risks nicotine vapor products pose to child welfare, which often pervades children. Among the most frequently real-world political debates, was so cited concerns are claims that nicotine deft that Toronto Star reporter Edward vaping harms the adolescent brain and Keenan coined the term “Lovejoy’s leads to future smoking—claims for Law.” In Keenan’s words, if one side which the evidence is weak, non- of a debate uses “the children” to existent, or invalidating. justify their position, one can assume The idea that nicotine damages it is an attempt to manipulate and that, adolescent brains or impairs their “they’re probably either lying, trying development are based primarily on to screw you over or hoping to distract rat and mouse studies that report you from the worthlessness of their relatively minor effects, like changes position.”62 Minton: The Double Standards of Cannabis and Nicotine 15
in learning, attention, and memory.64 increasing public acceptance of Interestingly, as a topic of debate, the cannabis use has made the continuation effects of substances on youth brain of prohibition on the drug unfeasible health seem exclusive to public for politicians and a bad target for discourse on nicotine and tobacco. As moral entrepreneurs. But these researchers Lynn Kozlowski of the circumstances may be tenuous and University of Buffalo and Kenneth temporary. As a recent article in The Warner of the University of Michigan Atlantic pointed out, 2020 democratic pointed out in 2017, there has been presidential candidate Joe Biden has little public interest in the impact on not fully endorsed the idea of cannabis brain health of other substances legalization despite broad public commonly used by youth, like support, particularly among democratic alcohol, cannabis, caffeine, and voters. One explanation provided for psychotropic medications. “If his reticence is the divergent treatment anything, the concern should be of nicotine vaping and cannabis. greater regarding kids’ cigarette Liberal lawmakers have argued for smoking but it was rarely brought into restrictions on vaping because of a discussions of youth smoking,” they lack of clarity on its health effects, but wrote.65 Given the fact that there are these same lawmakers have not many decades of studies on smokers, applied that standard to marijuana, most of whom began smoking as young which they mostly favor legalizing.66 adults, the evidence that nicotine Yet, should moral entrepreneurs causes brain damage or significant decide to make pot smoking their next cognitive impairment should be strong target, they could easily rely on all of and abundant. Until relatively recently, the same dubious arguments and in fact, a significant portion of youth evidence that have been used against reported daily smoking. If nicotine nicotine vaping, including the claim caused significant harms on the that cannabis may “harm” adolescent developing brain, it would be apparent brain development.67 in the scientific literature, but it is not. Another pseudoscientific argument Yet, the adolescent brain issue has regularly employed in public policy become one of the central arguments debates over drugs is the “gateway” used by anti-vaping activists. theory: the idea that the use of It is worth noting that while the relatively benign drugs, like cannabis adolescent brain issue has not yet been or nicotine, will lead to harder drugs a major factor in the public discourse and subsequent harms. The idea seems about cannabis, this could quickly to make logical sense, since individuals change. As this paper argues, who go on to use drugs like heroin 16 Minton: The Double Standards of Cannabis and Nicotine
typically begin experimenting with little to slow down activists, lawmakers, “softer” drugs. But the correlation and regulators from trying to implement does not necessarily prove that the increasingly restrictive rules and cannabis use, for example, caused a outright bans on the products. For these person to later use heroin, as many interests, there is little downside to As with other factors better explain individuals’ pursuing an anti-vaping agenda, as long likelihood to use either drug, such as a as it is perceived as being anti-Big cannabis proclivity for risk taking.68 Tobacco—even if achieving that the evidence agenda would have no benefit for, or Similarly, some have claimed that even harm, public health. indicates that vaping among youth, even experimental, will lead to future there is no smoking. But, as with cannabis, the Lower-Risk Nicotine: “gateway” evidence indicates that there is no “gateway” effect from using nicotine The Low-Hanging Fruit effect from When it comes to persuading vapor products. Research on the lawmakers to support their cause, using nicotine gateway effect finds that teens who are likely to smoke are also likely to anti-tobacco activists have discovered vapor products. that even more effective than the old try nicotine vaping, due to shared tactic of guilt by association is what characteristics, such as a greater could be called “hero by association”— propensity for risk taking, not because going after an easily identifiable vaping somehow causes them to villain to make yourself look heroic. progress to smoking.69 The clearest For ambitious politicians looking to piece of evidence against the vaping generate positive public attention, gateway theory is the fact that despite targeting “Big Tobacco” is among the nearly a decade of popular use, youth surefire ways to achieve that. smoking has not increased. In fact, the number of adolescents who smoke is The only potential pitfall to that now lower than it has ever been.70 approach is that Big Tobacco—real Moreover, most youth don’t vape, Big Tobacco—is an established, large, fewer vape regularly, and almost of all well-funded, and well-connected those who do vape regularly are or international industry. Attacking the were smokers, a behavior that would makers of cigarettes, farmers who grow cause at least as much damage tobacco, and smokers is not without as vaping. political risk. The vapor market, on the other hand, is nascent, smaller, and Yet, lack of evidence that nicotine has less consumer popularity and vaping harms or even poses a risk to political influence. Incurring the wrath the nation’s young people has done of the vapor industry and its customers Minton: The Double Standards of Cannabis and Nicotine 17
is a comparatively small risk for entire vapor industry, was part of politicians—but also politically less Big Tobacco all along.71 But the profitable if there is a widespread circumstances and regulatory pressure belief that vapor products are less created by anti-vaping advocacy made For anti-vaping harmful alternatives to smoking. such a merger a practical necessity for Juul to survive as a company. The advocates, the For anti-vaping advocates, the best main benefit Juul reaps from the environment for them to operate is the best environment current one, in which the majority of merger with Altria is expertise and money to contend with increasingly for them to the public believe that going after intense regulatory challenges and “vaping” is the same as taking on Big operate is the Tobacco. This situation allows lawsuits the company now faces as a result of anti-tobacco activism.72 current one, lawmakers who attack “vaping” to appear as if they are defenders of Notwithstanding that reality, anti- in which the public health against a powerful tobacco activists have successfully majority of the opponent like Big Tobacco, with little used the bugbear of Big Tobacco, guilt risk of political blowback—even by association, and exaggerated public believe when the outcome of their proposed concerns about adolescents’ health to that going after legislative solutions would help Big advance their policy agenda with Tobacco by crippling or outright considerable success. At no time in “vaping” is the eliminating its primary competitors. the past has their approach been more same as taking The main culprit anti-vaping activists brazenly on display than over the past year. on Big Tobacco. point to as evidence of Big Tobacco’s control of the nicotine vaping industry COVID-19 Gives Activists is the company Juul. Founded by a New Front Pax Labs, Juul began as a San Around July 2019, news stories began Francisco-based startup technology circulating about a sudden rash of firm with no connections to the people, mostly teenagers, being tobacco industry. However, as activists hospitalized with a mysterious and fomented panic over youth vaping and severe lung ailment linked to regulators put increasing pressure on “vaping.”73 As the number of cases the company, threatening its existence, began rising and details trickled out in 2018 Juul—then independent from through local news reporting, it Pax Labs—sold a 35 percent stake in became clear that the behavior shared the company to Altria Group— in common among most—if not all— formerly known as Philip Morris of the patients was not “vaping,” but Companies, Inc. The deal was the use of cannabis vaporizers misleadingly portrayed by activists of purchased illegally on the street.74 proof that Juul, and by extension the For example, when New York state 18 Minton: The Double Standards of Cannabis and Nicotine
authorities tested the vaping products contrary. And members of Congress used by those hospitalized with the have considered legislation to restrict lung ailment, they found that every the devices at the federal level.79 single one had been using at least one It wasn’t until January 19, 2020 that THC vaping product purchased the CDC acknowledged that illegal illicitly. They also found very high cannabis vaporizers tainted with levels of vitamin E acetate—an oil vitamin E acetate—not nicotine vaping that cannot be present in nicotine products—were behind the outbreak.80 e-liquid—in many.75 Soon other states But anti-vaping interests would not reported similar findings with all or have to wait long for a new opportunity nearly all patients admitting to using to spread unwarranted fears over illicit THC products, even in states nicotine vaping. where cannabis is not legal.76 Despite all this, the Centers for Disease At the beginning of the global Control and Prevention (CDC) outbreak of the novel coronavirus, downplayed the role of illicit THC SARS-CoV-2, it was assumed that products, urging consumers instead smoking was a risk factor for to avoid “all e-cigarette, or vaping contracting COVID-19 or for severe products.”77 progression of the disease. While there was no specific data on this novel Anti-tobacco activists across the virus, the assumption seemed country capitalized on the confusion reasonable, based on the fact that created by the CDC’s misleading smokers are at greater risk for certain messaging to spread fears about respiratory infections, like colds, flu, nicotine vapor products and advance pneumonia, and tuberculosis.81 their regulatory and legislative agenda. Governors in states like Michigan, However, anti-tobacco activists, in New York, and Massachusetts, and outside government, ignored the encouraged by anti-tobacco groups, emerging data indicating that smokers imposed emergency bans on nicotine did not appear to be more at risk of vaping products, despite all the COVID-19 than non-smokers, as well evidence indicating their having as the absence of any data on how nothing to do with the outbreak.78 vaping might affect progression of the Congress held two hearings on the disease. Instead, interest groups, health issue of nicotine vaping, at which organizations, and politicians around activists invited to testify gleefully the world seized on the opportunity blamed nicotine vaping products for to promote the idea that vaping is the outbreak of lung injuries, despite dangerous, and especially so during the demonstrable evidence to the the outbreak. Minton: The Double Standards of Cannabis and Nicotine 19
New York Mayor Bill de Blasio told academics, like Stanton Glantz, journalists that a 22-year old who was argued that vaping makes it harder for hospitalized with COVID-19 in early lungs to resist infection, even going so March had no known risk factors, far as to give the unsupported medical except his use of vaping products. advice that quitting vaping would lower “Why is a 22-year-old man stable but the risks associated with the disease.86 hospitalized at this point? The one This narrative has become increasingly factor we know of is he is a vaper,” difficult to sustain the more researchers de Blasio said. “So, we don’t know of look into the disease, and it now any preexisting conditions, but we do appears that nicotine—not smoking think the fact that he is a vaper is per se—may actually have a affecting this situation.”82 The protective effect. resulting speculation led to news articles and opinion pieces warning Early data on the outbreak from China that smokers and vapers could be at did not suggest that smokers were greater risk during the outbreak.83 more likely to contract COVID-19. In fact, they appeared less likely to be Health agencies added fuel to the fire. hospitalized with the disease. That data The National Institute on Drug Abuse contradicted assertions that smoking (part of the National Institutes of might explain why Chinese men— Health) issued a warning that over half of whom smoke—were dying “because it attacks the lungs, the at much higher rates than women, of coronavirus that causes COVID-19 whom only 3 percent smoke.87 But, could be an especially serious threat to when researchers looked into the those who smoke tobacco … or who smoking habits of patients in that vape.”84 The mere suggestion that country, they found just 1.4 to 12.6 nicotine vaping might have any impact percent of those hospitalized with the on the outbreak was proof enough for disease were classified as current activists and lawmakers to push for smokers, making smokers significantly temporary bans on the products at the underrepresented in hospitalized cases state and federal level. compared to the general public.88 Groups like the New York State This underrepresentation of smokers Academy of Family Physicians among COVID-19 patients has been appealed to the governor to institute a found by numerous studies in statewide ban on all tobacco products, populations around the world.89 These while members of the House Oversight counterintuitive results led some Committee appealed to the FDA to do researchers to question which the same across the nation.85 Activist ingredient or factor linked to smoking 20 Minton: The Double Standards of Cannabis and Nicotine
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