Seasonal flu guidance for 2018 to 2019 for healthcare staff and residential staff in the Children and Young People's Secure Estate Preventing and ...
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Seasonal flu guidance for 2018 to 2019 for healthcare staff and residential staff in the Children and Young People’s Secure Estate Preventing and responding to seasonal flu cases or outbreaks
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate About Public Health England Public Health England exists to protect and improve the nation’s health and wellbeing, and reduce health inequalities. We do this through world-leading science, knowledge and intelligence, advocacy, partnerships and the delivery of specialist public health services. We are an executive agency of the Department of Health and Social Care, and a distinct delivery organisation with operational autonomy. We provide government, local government, the NHS, Parliament, industry and the public with evidence-based professional, scientific and delivery expertise and support. Public Health England Wellington House 133-155 Waterloo Road London SE1 8UG Tel: 020 7654 8000 www.gov.uk/phe Twitter: @PHE_uk Facebook: www.facebook.com/PublicHealthEngland For queries relating to this document, please contact: health&justice@phe.gov.uk © Crown copyright 2018 You may re-use this information (excluding logos) free of charge in any format or medium, under the terms of the Open Government Licence v3.0. To view this licence, visit OGL. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. Published October 2018 PHE publications PHE supports the UN gateway number: 2018577 Sustainable Development Goals 2
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Title Guidance for 2018 to 2019 on preventing and responding to cases or outbreaks of seasonal flu in the Children and Young People Estate. Type Operational guidance Author/s Public Health England: National Health & Justice Team Respiratory Diseases Department, National Infections Service Prepared by Éamonn O’Moore National Lead for Health & Justice, Public Health England and Director of the UK Collaborating Centre for WHO Health in Prisons (European Region); Rachel Campbell, Magdalene Mbanefo-Obi & Susanne Howes (PHE Health & Justice Public Health Specialists & Co-Chairs, Health & Justice Health Protection Network); Maciej Czachorowski, Epidemiological Scientist, and Jo Peden, Consultant in Public Health, National Health & Justice Team, Health Improvement Directorate, PHE Other Gavin Dabrera, Consultant in Public Health , Department of Contributors Respiratory Surveillance, National Infection Service, PHE, Caroline Twitchett, Children’s Quality Lead, Health and Justice at NHS England PHE: Anita Turley, Julie Mann, Laura Pomeroy, Lipi Begum, Richard Pebody NHS England: Mark Gillyon-Powell, Denise Farmer, Christine Kelly, Christine Cook, Emily Nicol HM Prison & Probation Service: Rupert Baillie, Priscilla Wong HM Prison & Probation Service Youth Custody Service: Leah Goodrham, Lauren Brothwood and Stacie Dean Date of Issue October 2018 Revised Audience YOI Governors Secure Training Centre Directors Secure Children’s Home Managers Directors of Children’s Social Services Local Authorities Secure Accommodation Network Primary Healthcare Service Providers in the Children and Young People Secure Estate Occupational Health Services NHS England Health & Justice Commissioners and Children’s Commissioners PHE Health Protection Teams and Screening & Immunisation Leads (SILS) Directors of Public Health Secure Welfare Coordination Unit HMPPS YCS Placement Team Department for Education Review Date August 2019 3
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Contents About Public Health England 2 Glossary 5 1. Introduction 7 1.1 Background 8 2. Recommendations for action 12 2.1 Preparation 12 2.1.1 Seasonal flu vaccination for children 13 2.1.2 Seasonal flu vaccination for staff 15 2.1.3 Vaccination targets, coverage and recording in the Children and Young People’s Estate 16 2.2 Diagnosis & recognition of a case 18 2.3 Treatment and care 20 2.3.1 Accessing supplies of antivirals 21 2.3.2 Stock access of flu vaccine and antivirals 23 2.4 Prevention of transmission of infection 24 2.5 Outbreaks within the Children and Young People’s Secure Estate 25 Appendix 1 29 Appendix 2 31 Appendix 3 33 Appendix 4 38 Appendix 5 41 Appendix 6 43 4
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Glossary AV-PEP Anti-viral post-exposure prophylaxis COPD Chronic Obstructive Pulmonary Disease CYPSE Children and Young People Secure Estate (CYPSE) DfE Department for Education FES Field Epidemiology Service HAART Highly Active Antiretroviral Therapy HCWs Healthcare Workers HMPPS HM Prisons and Probation Service HPT Health Protection Team ILI Influenza-like Illness IRC Immigration Removal Centre JCVI Joint Committee on Vaccination and Immunisation MoJ Ministry of Justice NICE National Institute for Health and Care Excellence NIS National Infection Service OCT Outbreak Control Team PGD Patient Group Direction PHE Public Health England PPD Place of Prescribed Detention PPE Personal Protective Equipment PPO Prison and Probation Ombudsman PSD Patient Specific Direction SCH Secure Children’s Home 5
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate STC Secure Training Centre SOP Standard Operating Procedure YCS Youth Custody Service YCS Placement Team Youth Custody Service Placement Team YOI Young Offender Institution 6
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate 1. Introduction This guidance is for healthcare and residential/care staff in the Children and Young People Secure Estate (CYPSE) in England. It has been developed by Public Health England’s (PHE) National Health & Justice Team in collaboration with the Respiratory Diseases Department, National Infections Service Centre for Disease Surveillance and Control, NHS England Health & Justice Commissioners, Her Majesty’s Prisons and Probation Service (HMPPS) and Youth Custody Service (YCS) for their expertise and support in developing the guidance. This guidance considers children and young people in the secure estate. Specific guidance for the adult detained and secure estate has been previously published at: www.gov.uk/government/publications/seasonal-flu-in- prisons-and-detention-centres-in-england-guidance-for-prison-staff-and-healthcare- professionals The Children and Young Peoples’ Secure Estate The Secure Estate for Children and Young People (under 18s) currently includes: 4 Young Offender Institutions (YOIs) 3 Secure Training Centres (STCs) (one of which, Oakhill, is not currently within NHS England regulations) 14 Secure Children’s Homes (7 SCHs are welfare only). Commissioning of health services in the CYPSE Responsibility for commissioning health services in these secure settings sits with NHS England. This includes responsibility for commissioning health services in YOIs (under 18s), STCs and SCHs. Commissioning health services is carried out by local health and justice commissioning teams, of which there are 10 across England. All NHS England health and justice commissioners work closely with individual establishments within the CYPSE, to commission and procure healthcare providers who provide a range of high quality services which fully meet the needs of the cohort of children and young people identified. Commissioning is done on the basis of Health and Wellbeing Needs Assessments which are completed on a regular basis. NHS England Health and Justice teams commission to the ‘principle of equivalence’ which means that the health needs of a population constrained by their circumstances are not compromised and that they receive an equal level of service as that offered to the rest of the population. 7
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Influenza Influenza (often referred to as flu) is an acute viral infection of the respiratory tract (nose, mouth, throat, bronchial tubes and lungs) characterised by a fever, chills, headache, muscle and joint pain, and fatigue1. For otherwise healthy individuals, flu is an unpleasant but usually self-limiting disease with recovery within 2 to 7 days. Flu is easily transmitted and even people with mild or no symptoms can still infect others. The risk of serious illness from influenza is higher among children under 6 months of age, older people and those with underlying health conditions such as respiratory disease, diabetes, cardiac disease or immunosuppression, as well as pregnant women. Prescribed Places of Detention (PPDs) are at risk of outbreaks of seasonal flu due to large numbers of vulnerable individuals gathered together in an enclosed setting, some of whom will be in clinical risk groups, living in close quarters. Previous experience has demonstrated the importance of high vaccine coverage among vulnerable children and staff in the CYPSE in preventing and/or controlling such outbreaks. Further, early recognition and management of outbreaks can minimise both clinical and operational impacts. Maintaining the operational effectiveness of the CYPSE is essential to preserve a fully functional youth justice and welfare estate, and this makes it desirable to minimise the impact of seasonal flu within these settings. 1.1 Background The CYPSE runs the risk of significant and potentially more serious outbreaks, with large numbers of cases and potentially a higher rate of complications including mortality because: children live in close proximity in relatively crowded conditions, often with high degrees of social missing during activities there is considerable movement of children within the estate, with a high ‘churn rate’ within some establishments access to and capacity to healthcare could be limited if demand is high and transfer out to hospitals for assessment or care is complicated with demands on residential/care staff for bedwatch/escort services children in the secure estate may have a higher prevalence of respiratory illness (including asthma) immunosuppression and other chronic illnesses such as diabetes, than their peers in the community 1 PHE, Annual flu programme webpage (updated September 2018) https://www.gov.uk/government/collections/annual-flu- programme 8
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate A key principle in managing cases or outbreaks of seasonal flu is that children in the CYPSE should receive healthcare equivalent to people in the wider community including access to antiviral treatment, although the means of delivering such healthcare may differ from community models. An essential element of reducing the impact of influenza in the CYPSE is a whole- setting approach to the prevention, early identification and notification of illness, and prompt access to treatment including anti-virals. Vaccination of those in high clinical risk groups is an essential component of preparation for seasonal flu prevention. Therefore, high flu vaccine uptake, especially among individuals in clinical risk groups (sub-groups at high risk of complications from flu) is recommended2 (also see Appendix 1). All staff, (including residential/care staff), should play a key role in the early recognition of potential cases3 and report the information quickly to healthcare who must then ensure they report this to their local PHE Health Protection Team (HPT)4 promptly. Another key element of reducing the impact of influenza in CYPSE is by social distancing measures – reducing the contact between exposed and non-exposed children and staff. This will require isolation of those with symptoms where possible, or cohorting groups of people with symptoms if cases exceed isolation capacity. The role of the National Health & Justice Team Flu is an unpredictable disease, and the impact on the CYPSE is hard to predict. PHE’s National Health & Justice Team provides expert advice and support to responding Health Protection Teams (HPTs), and outbreak control teams (OCTs) conduct surveillance at national level, share intelligence with key partners and develop national guidance for use in preventing and managing outbreaks. Surveillance data on the number of outbreaks and their impact is collected centrally by the National Health & Justice Team, and this helps to inform real-time operational response as well as support planning and preparation. The enclosed nature of the CYPSE and the fact that children are living in close proximity to each other also means that flu can spread quickly. 2 DH, PHE and NHS England,National flu immunisation programme plan 2018-2019 (March 2018) https://www.gov.uk/government/publications/national-flu-immunisation-programme-plan 3 Diseases that healthcare teams in prisons and other secure settings should report to PHE (April 2015) https://www.gov.uk/government/publications/diseases-that-healthcare-teams-in-prisons-and-other-secure-settings-should- report-to-phe 4 Contact details of local health protection teams can be found at https://www.gov.uk/guidance/contacts-phe-regions-and-local- centres#region 9
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Learning from last winter The 2017 to 2018 flu season saw a large number of confirmed outbreaks of seasonal flu in the secure and detained estate in England and Wales; both Flu A and Flu B viruses. In total, 21 confirmed outbreaks were reported to the National Health and Justice team, 2 of which occurred in prisons in Wales and 3 in immigration removal centres (IRCs) in England. Many of these outbreaks occurred concurrently with some regions (North West, South East) particularly impacted. For all the outbreaks nationally, more than 250 prisoners and detainees reported influenza-like illness (ILI) and over 100 more were confirmed as having either influenza A or B, with about a dozen prisoners hospitalised following complications from flu. More than 80 members of staff were also affected (Figure 1). Fortunately, despite the significant impact on the secure and detained estate, there were no deaths directly attributable to influenza infection. Two outbreaks were also re-opened following reactivation of infection in prisoners and/or staff shortly after they were declared closed highlighting some of the challenges in prisons and similar institutions due to incomplete information and surveillance of staff and/or prisoners/detainees. There were no reported outbreaks in the CYPSE. 10
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Figure 1: Notified influenza outbreaks in the secure and detained estate (England and Wales; 2017 to 2018 flu season) by date reported, facility type, region, notification and closure dates. HMP = Her Majesty’s Prison; IRC = immigration removal centre. Source: National Health and Justice Team, PHE . 11
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate 2. Recommendations for action 2.1 Preparation The public health principles guiding action within the CYPSE are the same as those in the wider community, that is: vaccination of clinical risk groups (children in the CYPSE and staff – operational as well as healthcare staff) (see Appendix 1) vaccination of healthcare staff working in the CYPSE according to national guidance5 vaccination of residential and care staff who provide equivalent of a social care function to children with ill with flu in their rooms5. Carers working in Secure Children’s Homes can access the flu vaccine free of charge via community pharmacies as they are working in a registered care home. prompt diagnosis (either clinical or laboratory depending on circumstances including whether an outbreak situation) ensuring effective and appropriate care including access to antivirals for individuals who are ill or to prevent infection in those at risk of complications good infection control practice and resources to prevent transmission. PHE recommend that healthcare teams appoint a Flu Lead to oversee implementation of the preparations including the seasonal flu vaccine campaign. It is strongly advised that this includes holding a register of children in the defined clinical risk groups, (see Appendix 1), those offered vaccine, and those vaccinated, allowing an estimate of vaccine coverage to be calculated for the whole season or for points in time when there is an active outbreak. These data need to be regularly updated throughout the flu season The CYPSE should agree clear arrangements with their PHE HPT and NHS England Health & Justice Commissioners to ensure the secure settings know how to: order vaccine supplies in good time prior to the annual vaccination period plan and co-ordinate vaccination of eligible individuals recognise possible outbreaks and report them quickly (see Multi-agency contingency plan for disease outbreaks in prisons)6 5 PHE, Influenza: the green book, chapter 19 (updated 15 August 2018) https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/456568/2904394_Green_Book_Chapter_19_v10 _0.pdf 6 Multi-agency contingency plan for disease outbreaks in prisons, January 2017 https://www.gov.uk/government/publications/multi-agency-contingency-plan-for-disease-outbreaks-in-prisons 12
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate access public health advice and support, both in and out of office hours4 rapidly access viral testing (and processing of swabs) to support the need for timely diagnosis and “low threshold to treat” policy for at clinical risk groups access antiviral medication ensure adequate personal protective equipment is in stock Each outbreak should be risk-assessed and managed on a case-by-case basis. 2.1.1 Seasonal flu vaccination for children Influenza vaccine should be offered, ideally before influenza viruses start to circulate (in late September/ early October) to those in defined clinical risk groups as outlined in the annual flu letter2. All children aged 2 to 9 years old (but not 10 years or older) on 31 August 2018 should be given the flu vaccination. It is worth noting that there are a large number of children within secure settings who may not have been in mainstream education and so may have missed the opportunity to receive routine childhood vaccinations which they are eligible. Children between 2 years and under 18 years of age who are in a risk group should be offered a single dose of live attenuated influenza vaccine (Fluenz Tetra). Those children in a risk group who have never received influenza vaccine before and are aged between 2 and less than 9 years should be offered a second dose of Fluenz Tetra at least 4 weeks later. If Fluenz Tetra is unavailable for this second dose an inactivated influenza vaccine can be given. The full outline of high clinical risk groups are set out in Appendix 1. Clinical risk groups particularly relevant for the CYPSE are outlined below: people aged from 6 months to less than 65 years of age with a serious medical condition such as: chronic (long-term) respiratory disease, such as severe asthma, chronic obstructive pulmonary disease (COPD) or bronchitis chronic heart disease, such as heart failure chronic kidney disease at stage 3, 4 or 5 chronic liver disease chronic neurological disease, or motor neurone disease, or learning disability diabetes splenic dysfunction a weakened immune system due to disease (such as HIV/AIDS) or treatment (such as cancer treatment) morbidly obese (defined as BMI of 40 and above) 13
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate all pregnant girls (including those girls who become pregnant during the flu season) all children aged 2 to 9 (but not 10 years or older) on 31 August 2018 all primary school-aged children in former primary school pilot areas carers others involved directly in delivering health and social care The list above is not exhaustive, and the healthcare practitioner should apply clinical judgement to take into account the risk of flu exacerbating any underlying disease that a patient may have, as well as the risk of serious illness from flu itself. Flu vaccine should be offered in such cases even if the individual is not in the clinical risk groups specified above. For both healthy and at risk children under 18 years of age where Fluenz Tetra is medically contra-indicated, for example those who: have had severe anaphylactic reaction to a previous dose of the vaccine or component of the vaccine are severely immune-deficient due to conditions or immunosuppressive therapy such as: acute and chronic leukaemias; lymphoma have HIV infection and are not on highly active antiretroviral therapy (HAART) have cellular immune deficiencies are on high dose corticosteroids …an inactivated quadrivalent vaccine (Sanofi Pasteur MSD Split Virion BP) or Fluarix™ Tetra will be supplied. These vaccines should be ordered as per the usual mechanisms for the routine childhood immunisation programme via Immform (https://www.immform.dh.gov.uk/) as part of the national immunisation programme. The objectives of the influenza immunisation programme are to protect those who are most at risk of serious illness or death should they develop influenza and to reduce transmission of the infection, thereby contributing to the protection of vulnerable patients who may have a suboptimal response to their own immunisations. To facilitate this, healthcare teams are required to proactively identify all those for whom influenza immunisations are indicated and to compile a register of those children for whom influenza immunisation is recommended. Sufficient vaccine can then be ordered in advance and patients can be invited to planned immunisation sessions or appointments. Influenza vaccine should be offered, ideally before influenza viruses start to circulate, to: all those aged 65 years or older (for definition please see the annual flu letter for the coming/current season)2 all those aged 6 months or older in the clinical risk groups shown in Appendix 1. 14
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Mother and baby units There will be girls within the CYPSE who are pregnant and they should be encouraged to have the flu vaccination. Consideration should also be given to babies in the Mother and Baby unit who fall into a risk group and are eligible for the vaccine. 2.1.2 Seasonal flu vaccination for staff Different settings across the CYPSE will have various occupational health arrangements for residential/care and healthcare staff and it is important to include staff vaccination as part of preparation. Healthcare and social care staff and custodial staff (or those undertaking equivalent roles5) should be offered the seasonal flu vaccine in order to protect vulnerable patients in their care and avoid operational impact due to staff sickness absence. It is strongly recommended that as part of any secure setting’s flu strategy there is clear information on vaccine coverage in all appropriate staff groups. All Healthcare staff with direct contact with children in the CYPSE should be offered flu vaccination by their employer similar to healthcare staff in the community. This should form part of the organisation’s policy for the prevention of transmission of flu to help protect patients, and service users as well as staff and wider groups and should link directly to the organisation’s Occupational Health Policy. The national target for coverage among HCWs is 100%. Non-healthcare staff working with children in the CYPSE that have close contact with children in order to provide health and/or social care for them should be offered seasonal flu vaccine this year as per last season. Flu vaccines will be delivered for HMPPS employees by the Occupational Health provider. Other non-HMPPS employees with direct contact with children in the CYPSE should be offered flu vaccination by their employer. This should form part of the organisations’ policy for the prevention of transmission of flu to help protect patients, and service users as well as staff and wider groups and should link directly to the organisations Occupational Health Policy. Residential/care staff in the CYPSE will need to make a local risk assessment of which directly employed residential/care staff undertake a role analogous to a health and social care worker i.e. does their role require close contact with children affected by seasonal influenza e.g. those checking children in rooms, providing food and drinks, and medication or undertaking searches or providing bedwatch/escort duties or providing close personal care. Residential/care staff who are themselves in high clinical risk groups should seek vaccine from HMPPS Occupational Health provider or their GPs as locally directed. Occupational Health providers should provide information to CYPSE senior leaders on the number of staff in high clinical risk groups and their vaccine status (without providing patient identifiable information). 15
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Residential/care staff who are eligible for the seasonal influenza vaccine due to being in a clinical risk group (see Appendix 1) can access this from their GP practice or various pharmacies participating in the NHS seasonal influenza vaccination programme, free of charge. 2.2.3 Vaccination targets, coverage and recording in the Children and Young People’s Estate Relevant vaccination uptake targets established by the Department of Health and Social Care for the 2018/197 season are: vaccination of at least 75% of those aged 65 years and over vaccination of at least 55% of those in all clinical risk groups and maintain higher rates where those have already been achieved – ultimately, the aim is to achieve at least a 75% uptake in these groups given their increased risk of morbidity and mortality from flu vaccination of at least 100 % of HCWs and those custodial staff in analogous roles vaccination of at least 48% of preschool children aged 2 and 3 years old vaccination at least 65% of School aged children (in reception class & years 1 to 5) For children both the offer and uptake of the seasonal flu vaccine should be recorded in the CYPSE. Healthcare providers are encouraged to hold a register so that they can identify all children eligible for the flu vaccine. They are also encouraged to update the eligibility register throughout the flu season as this will help with coordination of the local flu vaccination programme. Risk group status should also be recorded on SystmOne and there should be a paper copy if SystmOne is not accessible. For staff groups, HCWs should be included in their employers’ seasonal flu vaccination programme as per national guidance for healthcare staff, with target uptake of at least 100%. Given the additional concern about flu outbreaks in closed secure settings, HCWs in the CYPSE are particularly encouraged to be vaccinated to protect vulnerable patients in their care and to prevent outbreaks. 2.14 Accessing vaccine supplies Healthcare providers access influenza vaccines in the same way as GP practices as detailed in Chapter 19 Green Book5. 7 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/694779/Annual_national_flu _programme_2018-2019.pdf 16
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Live attenuated influenza vaccine (Fluenz Tetra®) has been purchased centrally for children aged 2 to less than 17 years and for children aged 2 years to less than 18 years in clinical risk groups. For children under 18 years of age where Fluenz is medically contraindicated a quadrivalent vaccine or Fluarix™ Tetra will be supplied. Vaccine supplies Healthcare providers, or providers who provide childhood vaccination programmes to the CYPSE, should order flu vaccine supplies directly from Immform. They should ensure that they can estimate the number of vaccines needed that are sufficient for the size of the population at risk. This should be based on past and planned performance and expected demographic increase to ensure that everyone at risk is offered flu vaccine. In England, vaccines for routine immunisation programmes are ordered and delivered from a specialist pharmaceutical distribution company via the Department of Health and Social Care’s ImmForm website https://portal.immform.dh.gov.uk/ (see Chapter 11 and ImmForm helpsheet 13: immunisation.dh.gov.uk/immform-helpsheets). To register for an ImmForm account, please register online at https://portal.immform.dh.gov.uk/. In order to receive an allocation of the flu vaccine for children, the provider will need to e-mail Immform describing the number of at risk population in the site so that an allocation of the vaccine can be made. This may not be for 100% of the expected need. For further information and helpsheets on how to use ImmForm, please see immunisation.dh.gov.uk/immform-helpsheets. In the event of an outbreak of seasonal flu, during the flu season and if vaccination forms part of the actions being taken to manage the outbreak, influenza vaccine stock can be sourced from the following in priority order: Immform- providers will need to explain the basis of the increased need to Immform as this will exceed estimates for the current season or the outbreak may happen outside the season. pharmacy service providers contracted to provide pharmaceutical services to the CYPSE vaccine manufacturers If an outbreak of flu occurs outside the flu season, the outbreak control team (OCT) convened to manage the outbreak (see section 2.5) will agree whether flu vaccination forms part of the actions needed and where the vaccine should be sourced. 17
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Administration of influenza vaccines Influenza vaccines can be administered via a prescription for the vaccine. Alternatively to support vaccination of several people as part of nurse or pharmacist-led vaccination clinics a Patient Group Direction (PGD) can be used in line with legislation and NICE Guidance8. NHS England clinical and PHE leads within individual NHS England regions or localities usually authorise a flu vaccine PGD that can be shared and used by GP practices and health and justice providers within that locality/region. In the event that providers cannot access a local NHS England authorised PGD, the PHE template PGD for the vaccine (available here9) can be used by providers to either authorise within their organisation (i.e. in NHS Trusts) or to gain NHS England authorisation for its use in the health and justice sites (i.e. private healthcare providers). N.B.: Please note that sites which have healthcare commissioned by HMPPS must have the PGD authorised by the director/governor and not NHS England. 2.2 Diagnosis & recognition of a case It is important that all staff (residential/care staff as well as healthcare) are aware of the symptoms of influenza-like illness (ILI) and of the need to report possible cases promptly during the winter flu season to healthcare. Residential/care staff often have the most contact with children and are therefore well-placed to recognise increasing number of cases. Employees with signs and symptoms of ILI should seek advice from their GP and inform their line manager and OH. During the winter flu season, the majority of single cases will be diagnosed by healthcare staff on clinical grounds only based on the following clinical signs & symptoms and recognition of a case10. Testing may be considered, especially if an outbreak is suspected. Prompt action is necessary if ILI is suspected. A useful case definition for flu cases is provided in Table 1 below - this case definition may be modified once an OCT is called: 8 NICE. Good practice guidance Patient Group Directions August 2013 http://www.nice.org.uk/guidance/mpg2 9 PHE template for PGD (flu vaccine) https://www.gov.uk/government/publications/intramuscular-inactivated-influenza-vaccine- patient-group-direction-pgd-template 10 European Centre for Disease Prevention and Control, EU case definitions http://eur-lex.europa.eu/legal- content/EN/TXT/PDF/?uri=CELEX:32012D0506&qid=1428573336660&from=EN#page=16 18
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Table 1: Influenza (Influenza virus), clinical criteria for case definitions. Source: European Centre for Disease Prevention and Control, EU case definitions11, WHO12 ILI case definition An acute respiratory infection with: measured fever of ≥ 38 C° and cough; with onset within the last 10 days Swabbing to confirm infection During suspected outbreaks of flu in CYPSE testing of the first few cases to confirm the presence of the influenza virus should be given high priority. CYPSE healthcare teams should swab the first few presenting cases (up to 5) as soon as possible. Once flu is confirmed, all other cases meeting the clinical case definition are regarded as probable flu and no further testing is advised.13 However, the OCT may consider further testing towards the end of the outbreak to confirm that any new cases presenting with ILI can be discounted or in more complex situations eg. multiple wings/units with ILI or in more complex situations eg. multiple wings/units with ILI . Isolation and cohorting of cases: Children presenting with ILI should be isolated in single room accommodation and clinically assessed as soon as possible by the healthcare team. They should remain isolated until assessment. If a possible/probable case, they should continue to be isolated until resolution of their symptoms (usually 5 days from onset but may be longer in people with underlying medical conditions). Cohorting of cases: Ideally, children with possible/probable/confirmed cases of flu should be isolated in single accommodation. Where demand exceeds capacity, cases 11 European Centre for Disease Prevention and Control, EU case definitions: http://eur-lex.europa.eu/legal- content/EN/TXT/PDF/?uri=CELEX:32012D0506&qid=1428573336660&from=EN#page=16 12 http://www.who.int/influenza/surveillance_monitoring/ili_sari_surveillance_case_definition/en/ 13 You may consider swabbing children in clinical risk groups 19
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate may be cohorted together (doubling up). Where cases are concentrated in a particular unit or part of the secure setting, the OCT may consider cohorting all other cases in the same place but this requires both operational and security assessment and may not be practicable. Asymptomatic room sharer contacts of cases: where there are 2 or more people in a room and 1 becomes a confirmed/probable case, those room sharers’ contacts may be incubating infection or have sub-clinical or mild infection. However, because they pose an infection control risk, they should also be isolated from the general population. Practical operational considerations will need to inform any decision whether that means they stay where they are or can be moved to another location away from the ill roommate. 2.3 Treatment and care Symptomatic care should be offered including bed rest and oral fluids with paracetamol and/or ibuprofen provided as clinically indicated. The use of antivirals for prophylaxis and treatment of influenza according to NICE guidance14,15 remains an integral part of influenza control measures for closed secure settings where children are placed on youth justice and welfare grounds. Public Health England has published additional guidance on the use of antivirals16. Children with confirmed/probable flu that are in high clinical risk groups for complications of infection (see Appendix 1) should be considered for treatment with antivirals (usually oseltamivir or ‘Tamiflu). PHE recommends the consideration of treatment even in vaccinated children. Antiviral post-exposure prophylaxis of close contacts Children sharing a room with a confirmed case (or clinically confirmed in an outbreak) of seasonal flu, who are themselves in high clinical risk groups (see Appendix 1) and who have not been previously vaccinated with current seasonal influenza vaccine, should be offered antiviral prophylaxis provided this can be started within 48 hours from last exposure with oseltamivir or 36 hours for zanamivirvi. This advice applies even if the outbreak happens outside the period when flu is circulating in the community when antiviral use in the community is permitted by the NHS under NICE Guidance. Consideration should be made for those high risk contacts for whom vaccination is 14 Guidance on the use of antiviral drugs for the prevention of influenza (Technology Appraisal Guidance No.158) https://www.nice.org.uk/guidance/ta158 15 NICE. Guidance on the use of antiviral drugs for treatment of influenza (Technology Appraisal Guidance No. 168) https://www.nice.org.uk/guidance/ta168 16 Guidance on antiviral agents for the treatment and prophylaxis of Influenza (October 2018) https://www.gov.uk/government/publications/influenza-treatment-and-prophylaxis-using-anti-viral-agents 20
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate contraindicated, or in whom it has yet to take effect and those who have been vaccinated with a vaccine that is not well matched to the circulating strain of influenza virus, according to information from PHE (although this may differ to NICE guidance). During outbreak control team (OCT) meetings there may be consideration of other factors such as severity of illness/hospitalisations or case fatality rate to inform discussion about wider offer of antiviral prophylaxis. This discussion should include consultation with experts within the National Infection Service as well as the National Health & Justice Team, (see Section 0 on convening OCT). 2.3.1 Accessing supplies of antivirals The CYPSE flu plans should include details of the ordering process and supply of antivirals. These plans need to take into account the need for patients to commence antivirals within 24-48 hours of symptom onset. All supplies of antivirals to children should be recorded in their clinical records. There are 2 routes for children to access antivirals following a clinical assessment and diagnosis: Individual prescriptions or patient specific direction (PSD): The antiviral can be accessed by sending the prescription to the pharmacy for dispensing (ie. the pharmacy contracted to provide medicines to the CYPSE or PDD or an out of hours pharmacy) OR by using over-labelled stock supplies17 that allow the prescriber or registered healthcare professional to add the patient name and date to enable a prompt supply to the patient. This should be completed using standard operating procedures (SOPs) developed and ratified by the healthcare provider. A Patient Group Direction (PGD) authorised and handled as per NICE Guidance: Ideally PGDs need to be in place all the time and reviewed in advance of the flu season so they are ready for use for flu vaccination clinics and when the Chief Medical Officer advises the NHS that antivirals can be used when flu is circulating. PHE has produced 2 PGD templates18 for use in care homes only based on the guidance for antivirals but these can be adapted by health and justice providers for residential secure settings. These PGDs are for: Tamiflu for the treatment of people with flu-like symptoms Tamiflu for the prophylaxis of people at risk of getting the flu and who meet specific criteria - 10 days treatment 17 Over-labelled supplies must be procured from a licenced provider. The label usually has the dose pre-printed on it and allows the healthcare professional to add the patient name and date at the point of supply 18 Influenza post exposure prophylaxis and treatment: PGD templates https://www.gov.uk/government/publications/influenza- post-exposure-prophylaxis-and-treatment-pgd-templates 21
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate NB: Health and justice outbreaks may need a longer duration option of prophylaxis for high risk people. Up to 42 days of prophylaxis can be given within the product licence of Tamiflu. Alternative antivirals19,20 are available for patients who are unable to take Tamiflu. PHE provides a PGD template for flu vaccine which can be used for local authorisation and use as for other antimicrobials, Tamiflu can be supplied in-possession unless the patient is unable to manage their medicines where the Tamiflu is supplied in-possession of the young person, the antiviral must be handed to the patient by the healthcare professional who assesses the patient and makes the PGD supply: the antiviral must be from over-labelled stock and the name of the patient and the date added to the label by the healthcare professional N.B.: There is no national PHE PGD template for the supply of antivirals that can be used directly for H&J providers. PHE do publish template PGDs for antiviral treatment and prophylaxis for use in Care Homes which could be adapted locally for H&J patients. Providers will need to adapt the PHE Care Home template examples or develop and authorise antiviral PGDs in line with the legislation and NICE guidelines. If a PGD is not in place when an outbreak becomes likely or begins, here is what commissioners and providers can do: until a PGD is in place providers will have to write prescriptions for antivirals or flu vaccinations that need to be given NHS trust healthcare providers can authorise their own PGDs and so should be able to use their own mechanism to fast track the development and authorisation of PGDs for flu vaccine and Tamiflu private providers are not legally allowed to authorise their own PGDs; the provider will have mechanisms to write the PGD which MUST be authorised by the NHS England local commissioner − NHS England local teams will have processes for PGD authorisation usually led by a medical lead (H&J commissioners need to identify who the PGD authoriser is for their local team and facilitate the rapid PGD authorisation through this local process) 19 NICE Clinical Knowledge Summaries. Influenza – seasonal: prescribing information https://cks.nice.org.uk/influenza- seasonal#!prescribinginfo 20 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/648758/PHE_guidance_an tivirals_influenza_201718_FINAL.pdf 22
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate 2.3.2 Stock access of flu vaccine and antivirals Flu vaccine is supplied from Immform for people under 18 years old. Antivirals supplied under a PGD are usually sourced already over-labelled from the provider’s usual supplier of pre-packs/over-labelled medicines. For urgent supply during an outbreak it is acceptable for the antiviral to be supplied by adding the patient name, date and site name to the manufacturer’s pack and giving verbal instructions to the person about the dose, advising them to read the patient leaflet in the pack and to contact healthcare staff if they have any queries whilst taking it. See also PGD Q&A.21 Antiviral stock access should be checked and confirmed by commissioners in an outbreak and support to access urgent stock may be needed (e.g. supported by PHE colleagues). Potential stock from regional stockpiles is a last resort AND will only be activated if this can be accommodated by the pharmacy holding this supply and only if all costs for replacement of antivirals and pharmacy charges are directly reimbursed by the commissioner to the pharmacy. Where stock supplies of over-labelled antivirals are used plans should include: agreement of minimum stock levels based on previous year’s use with plans to have a small stick available at the start of the flu season access further stock promptly at the start of an outbreak amend the stock ordered this during an outbreak based on infection rates processes to check the antiviral stock regularly to ensure appropriate storage and expiry dates, audit the supplies made and re-order stock should this fall below minimum levels Where difficulties in accessing stock supplies is experienced, or a delay in access is anticipated then stocks may be accessible through the local Health Protection Team, although this should be a last resort. Where difficulties in accessing stock supplies are experienced, or a delay in access is anticipated then stocks may be accessible through the local Health Protection Team4, although this should be a last resort. 21 https://www.sps.nhs.uk/articles/what-are-the-legal-requirements-for-labelling-a-prescription-only-medicine-pom-issued-via-a- pgd-before-supply-to-the-patient/ 23
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate 2.4 Prevention of transmission of infection Detailed information on Infection control precautions to minimise transmission of acute respiratory tract infections in healthcare settings22 have been published by PHE and can also guide action in the CYPSE, advising that: during the winter flu season, children in the CYPSE with ILI should be diagnosed early and isolated to prevent further spread children in the CYPSE with ILI should be promptly assessed and isolated on their own or cohorted with other cases as soon as possible where demand for isolation exceeds capacity, consideration should be given to cohorting, with appropriate risk assessment of suitable cohortees, and the need for the movement of children in, out and around the secure setting should be reconsidered with a view to reducing these movements hand and respiratory hygiene measures should be re-emphasised to help minimise the spread of the infection (for both children and staff working there) if a symptomatic child needs to pass through areas where other people are waiting then they should wear a fluid repellent surgical mask identify close contacts of cases in clinical risk groups and, if not previously vaccinated with current seasonal influenza vaccine, offer antiviral prophylaxis as indicated above in suspected outbreaks, testing of the first 5 clinical cases should be carried out promptly to establish whether seasonal influenza is the cause of symptoms report cases to the local HPT so that advice on the public health aspects of more complex situations can be given residential/care staff and healthcare staff who are assessing children with suspected ILI and coming into close contact (less than 1 metre) to provide care should wear appropriate personal protective equipment, as per national guidance22 during the winter flu season, residential/care staff and healthcare staff with ILI should be excluded to stay away from work and be managed by their GP if they are in specific clinical risk groups; if staff become ill at work, they should be sent home immediately or isolated until they can be sent home residential/care staff with flu-like illnesses at home should seek medical care in the community using the usual mechanisms (i.e. via their GP if they belong to specific clinical risk groups) during an outbreak of influenza in the CYPSE, cases among staff should be reported to the HPT as well as cases among children 22 Public Health England. Infection control precautions to minimise transmission of acute respiratory tract infections in healthcare settings- October 2016 https://www.gov.uk/government/publications/respiratory-tract-infections-infection- control#history 24
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Visitation Symptomatic visitors should be excluded until no longer symptomatic and visitors with underlying health conditions and at risk of more severe infection (see Appendix 1) should be discouraged from visiting during an outbreak. Consistent with patient welfare, visitor access to symptomatic children should be kept to a minimum. Any visitors should be provided with hygiene advice. Non-urgent visits should be rescheduled until after the outbreak is over. 2.5 Outbreaks within the Children and Young People’s Secure Estate An influenza outbreak can be defined as: Two or more cases which meet the clinical case definition of ILI (or alternatively 2 or more cases of laboratory confirmed Influenza) arising within the same 48-hour period with an epidemiological link to the secure children’s home or secure training centre or young offender institution. If a seasonal flu outbreak is suspected or confirmed, it is strongly recommended that PHE Health Protection Teams convene an outbreak control team (OCT) meeting (for detailed guidance on the role of OCTs in prison or other detention settings see the Multi-agency contingency plan for disease outbreaks in prisons and other PPDs). The OCT will: collectively review information with partners on the extent and severity of infection (including information on patients requiring transfer out to hospital) collect and collate epidemiological data on clinical attack rates including wing specific attack rates to guide management of effective control measures review and advise on infection control practice consider vaccine coverage among children and staff groups and consider role of anti-viral treatment or prophylaxis for cases or contacts including staff The National Health & Justice Team23 should be invited to provide expert support, and experts from Field Services (FS) and/or the National Infection Service (NIS) should also be considered as contributors to the OCT. During an OCT, the following issues need to be considered: if not already done, ensuring that testing for seasonal influenza is carried out (See section on swabbing above); 23 Reached via health&justice@phe.gov.uk 25
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate consideration of the need to offer vaccination whether antiviral prophylaxis is required, who should receive it and how to include confirmation that a current in-date PGD is in place. operational status of the secure setting re: transfers in and out/regime restrictions etc. isolation and/or cohorting children as part of wider infection control practice ensuring that within the practicable constraints of the service, staff either deal with children who are symptomatic or asymptomatic but not both managing hospital admission if required communication and media issues risk assessment – a form on current risk assessment should be completed by the Senior Manager of the institution and the CCDC/CHP chairing the OCT (See Appendix 6) Specific infection control considerations: hand and respiratory hygiene measures should be re-emphasised to help minimise the spread of the infection (for both Children in the CYPSE and staff working there) chlorine based/bleach products are recommended by PHE for use in disinfecting and deep cleaning contaminated areas for infection control purposes; new guidance was published by PHE and HMPPS in 2017 on the use of Titan-Chlor tablets for cleaning purposes on recommendation of the OCT (see Appendix 3) if a symptomatic case needs to pass through areas where other people are waiting then they should wear a fluid repellent surgical mask residential/care staff and healthcare staff who are assessing children with suspected ILI and coming into close contact (less than 1 metre) to provide care should wear appropriate personal protective equipment (PPE), as per national guidance22 during any outbreak, custodial staff and healthcare staff with ILI should be excluded from work and be managed by their GP if they are in specific clinical risk groups: if staff become ill at work, they should be sent home immediately or isolated until they can be sent home custodial staff with flu-like illnesses at home should seek medical care in the community using the usual mechanisms (i.e. via their GP if they belong to specific clinical risk groups) During an outbreak of influenza in the CYPSE, cases among staff should be reported to the HPT as well as cases among children Specific considerations about communications during an outbreak: information for staff on the use of anti-viral medication for treatment and prevention purposes should be made available (see Appendix 4) 26
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate during an outbreak an advise and inform letter (see Appendix 5) can be issued to staff to inform them of the outbreak and provide relevant advice Specific considerations for the CYPSE around population management during an outbreak Where an outbreak has been declared, a dynamic risk assessment form should be completed by the Director and the PHE Consultant in Health Protection leading the OCT (see Appendix 6). Appendix 2 includes information on the process for limiting movement and transfers and should be discussed as part of the OCT. The OCT may consider recommending: restricting transfers out to other secure settings − this is to avoid ‘seeding’ an outbreak in other establishments; where required for security reasons, the receiving secure setting should be notified of outbreak. Avoid transferring symptomatic children as a priority − all infection control advice should be followed if transfers required restricting new receptions − this is to avoid ‘feeding’ an outbreak by introducing new vulnerable cases to the establishment; if it is not possible to restrict completely, new receptions should be: assessed to determine if in a risk group and if in a risk group considered for AV PEP and vaccine assessed for signs & symptoms of flu and symptomatic children who have just arrived at the secure setting should be isolated/cohorted immediately symptomatic children in clinical risk groups coming in from community may be swabbed and considered for treatment dose of antivirals if clinically appropriate Transfers to court In an outbreak situation, symptomatic children may not be suitable for court due to consideration both of clinical needs and infection control. Courts should be advised that a child is ill with flu and therefore may not be suitable for court appearance: Where it is necessary to have a symptomatic child attend court, a video link to the court should be considered as an alternative to personal appearance. If personal appearance is required, appropriate infection control measures should be implemented as per appropriate guidance. Asymptomatic children can attend court. If they are remanded in custody in a different secure setting, the receiving establishment should be advised that an outbreak is in play in the original secure setting and to be alert to signs/symptoms of flu emerging, a note 27
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate should be placed on SystmOne, or paper form if SystmOne is not available, for healthcare teams. New allocations from court Consideration should be given to redirecting new children allocated to an infected site. It should be noted, however, that in some circumstances and based on a secure setting’s function, that this may be sustainable for no more than a few days at most. 28
Seasonal flu guidance for healthcare and residential staff in the Children and Young People Secure Estate Appendix 1 Influenza vaccination should be offered to people in the clinical risk categories below: Clinical risk Examples (this list is not exhaustive and decisions should be category based on clinical judgement) Chronic respiratory Asthma that requires continuous or repeated use of inhaled or disease systemic steroids or with previous exacerbations requiring hospital admission. Chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema; bronchiectasis, cystic fibrosis, interstitial lung fibrosis, pneumoconiosis and bronchopulmonary dysplasia (BPD). Children who have previously been admitted to hospital for lower respiratory tract disease. see precautions section on live attenuated influenza vaccine Chronic heart Congenital heart disease, hypertension with cardiac disease complications, chronic heart failure, individuals requiring regular medication and/or follow-up for ischaemic heart disease. Chronic kidney Chronic kidney disease at stage 3, 4 or 5, chronic kidney failure, disease nephrotic syndrome, kidney transplantation. Chronic liver Cirrhosis, biliary atresia, chronic hepatitis disease Chronic Stroke, transient ischaemic attack (TIA). Conditions in which neurological respiratory function may be compromised due to neurological disease (included in disease (e.g. polio syndrome sufferers). Clinicians should offer the DES directions immunisation, based on individual assessment, to clinically for Wales) vulnerable individuals including those with cerebral palsy, learning disabilities, multiple sclerosis and related or similar conditions; or hereditary and degenerative disease of the nervous system or muscles; or severe neurological disability. Diabetes Type 1 diabetes, type 2 diabetes requiring insulin or oral hypoglycaemic drugs, diet controlled diabetes. 29
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