Schizophrenia, Delusional Symptoms, and Violence: The Threat/Control-Override Concept Reexamined
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Schizophrenia, Delusional Symptoms, and Violence: The Threat/Control-Override Concept Reexamined by Thomas Stompe, Qerhard Ortwein'Swoboda, and Hans Schanda and Link 1997; Tiihonen et al. 1997; RasSnen et al. 1998; Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Abstract Brennan et al. 2000a, 2000fc; Mullen et al. 2000jTAn In 1994 Link and Stueve identified a number of symp- overrepresentation of schizophrenia patients is repeatedly toms—called threat/control-override (TCO) symp- reported mainly among the most severe forms of violence toms—that were significantly more than others related (Petursson and Gudjonsson 1981; Lindqvist 1986; to violence. This was confirmed by some, but not all, Gottlieb et al. 1987; Eronen et al. 1996a, 1996*, 1996c, following studies. The contradictory results could be 1997; Wallace et al. 1998), confirming the prejudices of due to remarkable differences in sample compositions, the general population against these patients. The search sources used, and definitions and periods of recorded for reliable predictive factors for future violence is a mat- violence, but they are mainly due to problems defining ter of special interest (Steadman et al. 1993; Monahan and the TCO symptoms. To reexamine the validity of the Steadman 1994; Monahan and Appelbaum 2000; TCO concept from an exclusively psychopathological Steadman and Silver 2000). position, we compared in a retrospective design a sam- Clinical diagnoses as more or less stable (actuarial) ple of male offenders with schizophrenia not guilty by predictors can in fact provide (at least partly) statistically reason of insanity (n = 119) with a matched sample of significant results, yet they suffer from a lack of speci- nonoffending schizophrenia patients (n = 105). We ficity. Dynamic psychopathological factors such as delu- could find no significant differences regarding the sional/psychotic symptoms seem to have a higher predic- prevalence of TCO symptoms hi the two groups dur- tive value and have always been associated with violent ing the course of illness. The only statistically signifi- behavior (B6ker and Hafner 1973; Taylor 1985; cant discriminating factors were social origin and sub- Krakowski et al. 1986; Link et al. 1992). Some years ago, stance abuse. Yet, taking into account the severity of Link and Stueve identified among the range of delusional offenses, TCO symptoms emerged as being associated symptoms a few that were significantly more frequently with severe violence. This effect is primarily attribut- than others related to violence. As these symptoms able to the comparatively unspecific threat symptoms. describe a patient's feeling of being "gravely threatened Control-override, to be seen as more or less typical for by someone who intends to cause harm" (p. 143) and of schizophrenia, showed no significant association with an override of self-control through external forces, they the severity of violent behavior. were called threat/control-override (TCO) symptoms Keywords: Schizophrenia, violence, threat/con- (Link and Stueve 1994). These findings were corroborated trol-override symptoms. in general by several other studies (Swanson et al. 1996, Schizophrenia Bulletin, 30(l):31^44, 2004. 1997; Link et al. 1998), and meanwhile the TCO concept has found its way into the literature dealing with risk assessment and risk management (e.g., Bjtfrkly 2000; Regardless of the much more important influence of gen- Cooke 2000). eral criminogenic factors such as (antisocial) personality However, scepticism was expressed by Mullen disorders and substance abuse, newer studies with differ- (1997) regarding the rates of thought insertion and feel- ent designs are confirming a modest but significant link ings of external control in the nonpsychotic Link and between mental illness and criminal/violent behavior (Lindqvist and Allebeck 1990; Swanson et al. 1990; Hodgins 1992; Link et al. 1992; Wessely et al. 1994; Send reprint requests to Dr. T. Stompe, Justizanstalt GSllersdorf, Hodgins et al. 1996; Modestin and Ammann 1996; Stueve Gflllersdorf 17, 2013 Austria; e-mail: thomas.stompe@chello.at. 31
Schizophrenia Bulletin, Vol. 30, No. 1, 2004 T. Stompe et al. Stueve community sample (1994). He pointed out that Stueve (1994) definition for the Triangle Mental Health "whatever is being measured it is unlikely to be the rela- Survey (TMHS) subsample using the corresponding items tively uncommon passivity phenomena, at least not in the from the PERI, and the Swanson et al. (1996) definition form traditionally recognised" (Mullen 1997, p. 7). for the Epidemiologic Catchment Area (ECA) subsample. And, in fact, the first prospective investigation based Probably the most precise definition of psychopathology on data from five face-to-face interviews within 1 year in was that of Appelbaum et al. (2000), who used the more than 1,000 patients (MacArthur Violence Risk MacArthur-Maudsley Delusions Assessment Schedule, an Assessment Study) (Appelbaum et al. 2000) was not able adaptation of the Maudsley Assessment of Delusions to confirm the earlier positive results. Moreover, Schedule as an expert rating (Appelbaum et al. 1999) and, Appelbaum et al. found that "body/mind control delusions additionally, patients' self-reports. . . . displayed a negative relationship to the incidence of Given that (in concordance with DSM definitions) violence" (2000, p. 568), at least during the first two fol- especially "transitivistic" passivity phenomena are pri- lowup assessments in their sample. Their effort to dupli- marily found in patients with schizophrenia and related cate the designs of the earlier studies (retrospective self- disorders, we tried to reexamine the validity of the TCO reports) as closely as possible initially led to significant concept from an exclusively clinical/psychopathological Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 results, but these were eliminated after controlling for standpoint, comparing a sample of offenders with schizo- anger and impulsivity measures. phrenia found to be not guilty by reason of insanity These contradictory results may be caused not least by (NGRI) with a matched sample of nonoffending schizo- methodological problems. Table 1 shows that—apart from phrenia patients regarding the frequency of TCO symp- the differences in the sample compositions—the instru- toms and their possible association with violent behavior. ments used, the definitions of violence and TCO symptoms, and the periods and procedures of recording were remark- ably divergent: the lay-administered Psychiatric Methods Epidemiology Research Interview (PERI) and the Diagnostic Interview Schedule (Link and Stueve 1994; According to Austrian law, persons who have committed a Swanson et al. 1996, 1997; Link et al. 1998), DSM-1II-R severe offense (i.e., under threat of a penalty of more than diagnoses based on hospital charts and mental health center 1 year of imprisonment) in causal connection with a men- records (Swanson et al. 1997) or face-to-face interviews by tal disorder and who are found NGRI by the courts are clinically trained research staff (Appelbaum et al. 2000), exculpated and have to be treated under restriction order the psychiatrist-administered Schedule for Affective for an indefinite period of time, most of them in the Disorders and Schizophrenia (SADS) (Link et al. 1998), Justizanstalt Gollersdorf, Austria's central high-security and expert-administered special instruments such as the institution for male mentally ill offenders (Schanda et al. MacArthur-Maudsley Delusions Assessment Schedule, the 2000). Novaco Anger Scale, and the Barratt Impulsiveness Scale Patients of the Justizanstalt Gollersdorf with a clini- (Appelbaum et al. 2000). The periods of several compo- cal diagnosis of schizophrenia who had been delusional at nents of recorded violence were past month, past year, and any time during their illness were interviewed by means past 5 years (Link and Stueve 1994); past year and whole of the SADS: Lifetime Version (SADS-L) (Spitzer and adult life period (Swanson et al. 1996) and—additionally— Endicott 1977). Those who met DSM-IV criteria for past 5 years and following 18 months (Swanson et al. schizophrenia (American Psychiatric Association 1994) (n 1997); past 5 years (Link et al. 1998); and—in the only = 119) were included in the study and further checked prospective study—during several followup intervals (10 with the SADS-L as to substance abuse. Additionally, the weeks each) (Appelbaum et al. 2000). All but Appelbaum delusional symptomatology was documented by means of et al. (and partly Swanson et al. 1997) were dealing with a semistructured questionnaire (Fragebogen zur Erfassung self-reported aggression. psychotischer Symptome [FPS]), developed for transcul- The periods of recorded TCO symptoms were past tural studies on the psychotic symptomatology of schizo- month/past year (Link and Stueve 1994), past year and phrenia patients (Stompe and Ortwein-Swoboda, unpub- adult life period (Swanson et al. 1996), past year (Link et lished manuscript, 1999). al. 1998), and every 10 weeks (Appelbaum et al. 2000). As the earlier studies on TCO symptoms primarily From the position of a clinical psychiatrist, the sev- investigated violent behavior in general without reference eral definitions of the TCO symptoms are of special inter- to legal categories, we decided to use for reason of better est. In Link and Stueve (1994), thought withdrawal and comparability the classification according to Taylor movement control were not counted as TCO symptoms— (1985) targeting primarily the severity of the violent acts unlike in Swanson et al. (1996). In Swanson et al. (1997), (in our case, the index offenses leading to detention in the two different formulations were applied—the Link and high-security institution). 32
Table 1. Sample characteristics, study designs, diagnostic instruments, definitions, and periods of recorded violence and TCO symptoms In previous studies on TCO symptoms o Link and Stueve Swanson et al. Swanson et al. Link et al. Appelbaum et al. (1994) (1996) (1997) (1998) (2000) Sample 232 patients (various 10,066 community residents TMHS (n= 169) plus ECA Community sample (n •= 2,678) 1,136 discharged hospital in- £ E. characteristics, diagnoses), 521 community (ECAdata) (n = 129) pooled sample of patients, various diagnoses, 5 P study design residents persons with psychiatric followup evaluations during 1 yr disorders (various diagnoses) o a Retrospective Retrospective Retrospective (TMHS Retrospective Prospective E. partly prospective) •a Relevant PERI (lay administered) DIS (lay administered) TMHS: DSM-llt-R PERI (lay administered) DSM-ill-R checklist, o diagnostic (hospital charts, mental SADS (psychiatrist MacArthur-Maudsley Delusions instruments health center records) administered) Assessment Schedule, Novaco PERI Anger Scale, Barratt I ECA: DIS Impulsiveness Scale (research s; interviewers, consultant o_ psychiatrists) Aggression Self-reported Self-reported Self-reported (TMHS also Self-reported Self-reported, collaterals, (sources, hospital charts, court arrest records period of records) recording) Hitting (past mo, past yr) Hitting, injuring partner or TMHS: any violent acts Physical fight, weapon use Batteries resulting in physical Fighting (past 5 yrs) child, physical fight weapon toward others (following 18 injury or involving use of a Weapon use (past 5 yrs) use, physical fight while mos, past 5 yrs) weapon, sexual assaults, threats drinking ECA: see Swanson et al. made with a weapon in hand (1996) Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Past yr, adult life period Past 5 yrs During each followup period (10 wkseach) TCO 1. Thought/mind control 1. Thought/movement control TMHS: see Link and 1. Thought/mind control 1. Belief of being under external symptoms 2. Thought insertion 2. Thought Stueve (1994) (period of 2. Thought insertion control (actions, thoughts) (definition, 3. Feeling that other people insertion/withdrawal recording unknown) 3. Feeling that others wish to 2. Thought insertion period of wish to do harm 3. Belief that others are ECA: see Swanson et al. do harm 3. Thought withdrawal recording) plotting, trying to hurt (1996) 4. Persecutory delusions 4. Belief of being hypnotized, or poison 5. Delusions of control being under magic perform- 4. Belief that others are ance, or being hit by X-rays following or laser beams 5. Belief that people are spying 6. Belief that people are following 7. Belief of being secretly tested, experimented on 8. Belief that someone is plot- ing, trying to hurt, poison Past mo, past yr (50% Past yr, adult life period Past yr During each followup period of sample each) Note.—OIS •» Diagnostic Interview Schedule; ECA = Epidemiologic Catchment Area; PERI = Psychiatric Epidemiology Research Interview; SADS = Schedule for Affective Disorders and Schizophrenia; TCO >= threat/control-override; TMHS - Triangle Mental Health Survey.
Schizophrenia Bulletin, Vol. 30, No. 1, 2004 T. Stompe et al. Taylor defines "minimal" (la—verbally aggressive, groups, arranged in three major classes (upper, middle, lb—carrying a weapon which was not used, lc—minimal lower). The scale has often been used in epidemiologic damage to property when this was accidental) and "mod- and clinical investigations (e.g., Schepank 1990; Stompe erate" violence (2a—actual bodily harm, 2b—sexual et al. 2000). offense under force, 2c—using an offensive weapon but The control sample was drawn from the consecutive without causing injury, 2d—damage to property when this admissions to the Psychiatric University Clinic of Vienna was the main intent) as "low violence"; "moderately seri- and an affiliated rehabilitation center for chronic schizo- ous" (3a—grievous bodily harm, 3b>—damage to property phrenia patients. Patients with previous convictions were when this was extensive and could have threatened life) excluded. The files of all (also former) inpatient treat- and "serious" violence (4a—victim died, 4b—life actually ments were checked for every clue of violence not offi- endangered and victim detained in hospital more than 24 cially prosecuted. Moreover, the patients were asked for hours) as "high violence." former violent behavior, although not as systematically as As a certain degree of dangerousness is the legal pre- in the investigations cited in table 1. If there was a clear requisite for the detention of a mentally ill offender (see indication of (usually minor) forms of violence in the Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 above), Taylor's categories lb, lc, and 2a did not apply to descriptions of the admission procedures or in the collat- our sample. So we equated our legal categories severe eral reports documented in the files, the patient was threat and compulsion with Taylor's item "verbally excluded from the study. Finally, our control sample con- aggressive" (la), sexual offenses without physical injury sisted of 105 male schizophrenia patients matched within of the victim with "sexual offense under force" (2b), rob- certain ranges for age, duration of illness, and schizophre- bery and severe compulsion using a weapon with "using nia subtypes. The diagnostic assessment of the control an offensive weapon but without causing injury" (2c), and group was identical with that of the offender group. severe damage to property (including a part of the cases The SADS-L and FPS ratings were carried out by of arson) with "damage to property when this was the two experienced psychiatrists (T.S. and G.O.-S.) and were main intent" (2d) and classified them as "low violence." based on face-to-face interviews and the files from previ- Severe bodily injury was equated with "grievous bodily ous hospitalizations. This allowed the documentation of harm" (3a), arson under certain (especially dangerous) TCO symptoms present at any time during the illness. The circumstances with "damage to property when this was period of recruitment for both groups was 1994 to 1998. extensive and could have threatened life" (3b), and mur- Following the psychopathologically oriented German der and attempted murder with Taylor's categories serious tradition (Kraepelin 1909-1915; Jaspers 1913; Schneider violence with (4a) and without (4b) death of the victim, 1939), the FPS is subdivided into three sections (delu- all classified as "high violence." sions, Schneiderian first rank symptoms, hallucinations). Without a doubt, objections could be raised to clas- So our definition of TCO symptoms is—in contrast to the sify sexual offenses under force as equal to, for example, definitions used by Link and Stueve (1994), Link et al. severe verbal aggressiveness or actual bodily harm. But (1998), and Swanson et al. (1996, 1997)—reduced to the ranking of Taylor is committed not to legal or moral clear persecutory delusions and to the typical (schizo- standards as criteria for severity but only to the amount of phrenic) "passivity phenomena" (Jaspers 1913) addressed violence. Even so, if a sexual assault included the bodily by Mullen (1997). injury of the victim, it had to be rated as high violence. As Appendix 1 shows the translation of those FPS items our sample included only four cases of sexual assault, corresponding with the TCO symptoms. By threat we none of them with severe bodily injury, we decided to fol- understand the delusional belief of imminent danger low the Taylor classification (1985). caused by others. In concordance with Swanson et al. Forty-seven offenders had committed low-severity (1997) we discriminate between the delusional idea of offenses, and 68 high-severity offenses; in four cases a being vitally threatened by physical aggression or poison- definite classification was not possible because of the ing and the delusion of being followed by one or more incompatibility with our legal definitions. persons. By control-override we understand the loss of The social levels of origin were documented by control over one's own thoughts, feelings, movements, means of the Soziale Selbsteinstufung, a scale measuring and actions in connection with the belief that an external the prestige of the patients' fathers' professions (Kleining power has taken control over these functions. We fol- and Moore 1968). This scale is based on a survey in a rep- lowed Kurt Schneider's definition insofar as the psychotic resentative sample of 48,312 persons in Germany who influence on volition has to be experienced directly by the were asked to choose one of 36 options to identify their patient Under "made volition," Schneider (1939) summa- professions and their fathers' professions. The ratings rized the first rank symptoms of made motion, made were validated by sociologists and placed in nine sub- action, made thoughts, and made emotions. He described 34
Schizophrenia, Delusional Symptoms, and Violence Schizophrenia Bulletin, Vol. 30, No. 1, 2004 thought insertion and thought withdrawal as belonging to stance-related disorders, and models 3 and 4 TCO symp- the experiences of being influenced. We ascertained them toms, controlling for the prior variables, thus leading from separately and then united both under the term "thought the general to the particular. The results are presented as shifting." So, control-override consists of the two symp- odds ratios. All data analyses were carried out with the tom clusters "made volition" and "thought shifting." To SPSS version 6.1 for Windows (Buhl and Zofel 1995). scrutinize the interrater reliability for the TCO symptoms, the interviews of 48 patients were rated independently by the two psychiatrists (T.S. and G.O.-S.). In these cases Results Cohen's kappa for the single items was 0.75 to 0.98 with Table 2 shows the sociodemographic and basic clinical the exception of made emotions. For the diagnosis of data of both offender and nonoffender groups. There are schizophrenia according to the SADS-L, Cohen's kappa no significant differences regarding age, age at onset, was 0.96. duration of illness, and schizophrenia subtypes (DSM-IV). In a first step we assessed the possible association of However, the overrepresentation of schizophrenia patients substance abuse, social origin, and TCO symptoms with with substance-related disorders (with the exception of Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 violence by means of univariate statistics (2-tailed chi- nonalcohol substance abuse, dependence) is highly signif- square test). Subsequently, stepwise forward logistic icant in the offender group, which also originates more regression was used to examine the risk of violence with often from lower social levels. and without TCO symptoms and the generally accepted Table 3 displays the prevalence of TCO symptoms in criminogenic variables social level of origin and sub- the two groups. One can see that TCO symptoms could be stance-related disorders. Model 1 is based on the single registered very frequently in a 7-year course. Threat (feel- independent variable social origin, model 2 adds sub- ing of being poisoned, hurt, or followed) was rated far Table 2. Age, age at onset, duration of Illness, schizophrenia subtypes, substance-related disorders (DSM-tV), and social class of origin In offending and nonoffending male schizophrenia patients Offenders Nonoffenders (n = 119) (n=105) Significance Mean ± SD Mean ± SD Age 29.9 ± 9.2 29.318.7 ns1 Age at onset 22.5 ± 6.5 22.2 1 6.2 ns1 Duration of illness 7.416.8 7.2 1 6.2 ns1 n(%) n(%) Chi-square Schizophrenia subtypes Disorganized 6 (5.0) 6 (5.7) 0.05 Catatonic 11 (9.2) 8 (7.6) 0.19 Paranoid 88 (73.9) 82(78.1) 0.52 Residual 11 (9.2) 7 (6.7) 0.50 Undifferentiated 3 (2.5) 2(1.9) 0.09 Additional substance-related disorders 64 (53.8) 29 (27.6) 15.72"* Alcohol abuse, dependence 21 (17.6) 8 (7.6) 4.98* Nonalcohol abuse, dependence 21 (17.6) 20(19.0) 0.07 Polysubstance-related disorder 22(18.5) 1 (1.0) 18.62*** Social class of origin2 Upper 3 (2.5) 13(12.4) 8.18" Middle 56(47.1) 54(51.4) 0.43 Lower 60 (50.4) 38 (36.2) 4.59* Note.—ns " nonsignificant; SD =• standard deviation. 1 ftest. 2 Prestige of the profession of patients1 fathers according to Kieining and Moore (1968). * p < 0.05; " p < 0.01; *** p < 0.001 35
Schizophrenia Bulletin, Vol. 30, No. 1, 2004 T. Stompe et al. more often than was control-override. Within the control- A completely different situation emerges when high- override cluster, those symptoms summarized under and low-violence offenders are compared. Table 5 shows thought shifting occurred more often than experiences of that the general criminogenic factors (substance-related external influence on volition. Neither on the level of sin- disorders and social class of origin) have no impact on the gle symptoms nor on that of symptom clusters could we discrimination between high and low violence. But, in find any differences between offenders and nonoffenders. contrast, residual and disorganized schizophrenia sub- These results were confirmed by a multivariate proce- types are overrepresented in low, paranoid subtype in dure (table 4): A stepwise forward logistic regression high-violence offenders, although the statistical signifi- model based on only the social class of origin (model 1) cances are not as pronounced as in the differences regard- led to a statistically significant result. Adding substance- ing substance abuse in the comparison of offenders and related disorders (model 2) improved the statistical signif- nonoffenders (table 2). icance, while the inclusion of TCO symptoms (model 3) Also, regarding TCO symptoms there were differ- was not able to ameliorate the statistical significance of ences between the two offender groups (table 6). Again, the model chi-square. threat was the symptom cluster registered most frequently. Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Table 3. Prevalence of TCO symptoms during entire course of illness in offending and nonoffending male schizophrenia patients Offenders Nonoffenders (n = 119) (n = 105) n(%) n(%) Chl-square Threat 100(84.0) 81 (77.1) 1.71 Being poisoned, hurt 59 (49.6) 48 (45.7) 0.33 Being followed 70 (58.8) 62 (59.0) 0.00 Control override 50 (42.0) 51 (48.6) 0.97 Made volition 28 (23.5) 27 (25.7) 0.14 Made motions 17(14.3) 17(16.2) 0.16 Made actions 19(16.0) 15(14.3) 0.12 Made thoughts 7 (5.9) 9 (8.6) 0.61 Made emotions 9 (7.6) 4 (3.8) 1.44 Thought shifting 42 (35.3) 40(38.1) 0.20 Thought insertion 40 (33.6) 37 (35.2) 0.07 Thought withdrawal 9 (7.6) 14(13.3) 0.16 Threat and/or control-override symptoms 105(88.2) 95 (90.5) 0.29 Table 4. Stepwise forward logistic regression models for risk of violence In male schizophrenia patients Model 1 Model 2 Model 3 Social origin + Substance-related + TCO symptoms disorders Risk factors OR (95% Cl) OR (95% Cl) OR (95% Cl) Offenders (n= 119) vs. Social origin 1.93" (1.24-3.02) 1.83*(1.15-2.89) 1.83* (1.15-2.89) nonoffenders (n = 105) Substance-related 2.94"* (1.65-5.25) 2.94*** (1.65-5.25) disorders TCO Symptoms Model chi-square 8.74" 22.66"" 22.66**** Note.—Cl - confidence interval; OR •= odds ratio; TCO = threat/control-override. Parameter significance tests based on WakJ chi-square testwfthc#= 1. * p < 0.05; " p < 0.01; *** p < 0.001; *"* p < 0.0001 36
Schizophrenia, Delusional Symptoms, and Violence Schizophrenia Bulletin, Vol. 30, No. 1,2004 Table 5. Age, age at onset, duration of Illness, schizophrenia subtypes, substance-related disorders (DSM-iV), and social class of origin In high- and low-violence male schizophrenia offenders1 High violence Low violence (n = 68) (n = 47) Significance II Mean ± SD Mean ± SD Age 30.2 ±8.1 29.4 ± 7.8 m? Age at onset 23.1 ±6.3 21.7 ±6.8 m? Duration of illness 7.1 ±7.1 7.3 ± 7.0 ns> n(%) n(%) Chl-square Schizophrenia subtypes Disorganized 1 (1.5) 5(10.6) 4.72* Catatonic 9(13.2) 2 (4.3) 2.59 Paranoid 55 (80.9) 30 (63.8) 4.19* Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Residual 3 (4.4) 8(17.0) 5.11* Undifferentiated 2 (4.3) 2.94 Additional substance-related disorders 34 (50.0) 27 (57.4) 0.62 Alcohol abuse, dependence 10(14.7) 10(21.3) 0.84 Nonalcohol abuse, dependence 14(20.6) 7 (14.9) 0.60 Polysubstance-related disorder 10(14.7) 10(21.3) 0.84 Social class of origin 3 Upper 1(1.5) 2 (4.3) 0.85 Middle 33 (48.5) 23 (48.9) 0.00 Lower 34 50.0 22 (46.8) 0.11 Note.—ns = nonsignificant. 1 Severity of offense rated according to Taylor (1985), total n = 115, In 4 cases definite classifications not possible because of incompati- bility wtth legal definitions. 2 nest 3 Prestige of the profession of patients' fathers according to Kieining and Moore (1968). * p < 0.05 Table 6. Prevalence of TCO symptoms during entire course of illness in high- and low-violence male schizophrenia offenders1 High violence Low violence (n = 68),n(%) (n = 47),n(%) Chl-square Threat 64(94.1) 33 (70.2) 12.03*" Being poisoned, hurt 39 (57.4) 19(40.4) 3.19 Being followed 42(61.8) 25 (53.2) 0.84 Control override 30(44.1) 19(40.4) 0.16 Made volition 17(25.0) 10(21.3) 0.21 Made motions 9(13.2) 7 (14.9) 0.06 Made actions 11 (16.2) 7 (14.9) 0.04 Made thoughts 4 (5.9) 3 (6.4) 0.01 Made emotions 9(13.2) 4 (8.5) 1.44 Thought shifting 27 (39.7) 14(29.8) 1.19 Thought insertion 26 (38.2) 13(27.7) 1.39 Thought withdrawal 6 (8.8) 3 (6.4) 0.23 Threat and/or control- 66(97.1) 36 (76.6) 11.61"* override symptoms Note.—TCO = threat/control-override. 1 Severity of offense rated according to Taylor (1985), total n = 115, in 4 cases definite classification not possible because of incompatibil- ity wtth legal definitions. *"p< 0.001 37
Schizophrenia Bulletin, Vol. 30, No. 1, 2004 T. Stompe ct al. But despite the fact that also 70.2 percent of the low-vio- Apart from general criminogenic factors, delusional lence offenders exhibited threat symptoms during their ill- symptomatology has always been considered a major trig- ness, the differences between the low- and the high-vio- ger of violent behavior (B5ker and Hafner 1973; Rofrnan lence groups reached statistical significance (p < 0.001). et al. 1980; Taylor 1985). So the TCO concept introduced In contrast, control-override symptoms, taken separately by Link and Stueve (1994) appeared to be plausible at or as a group, showed no association with the severity of first glance in concordance with common clinical knowl- the offense. edge and was seen as an important step forward in the In a stepwise forward logistic regression analysis, improvement of risk assessment in mental patients. The neither social origin (model 1) nor substance-related dis- results of Link and Stueve (1994) were confirmed by a orders (model 2) were able to separate the high- from the number of studies (Swanson et al. 1996, 1997; Link et al. low-violence group (table 7). Only the inclusion of TCO 1998), with the exception of the only prospective one symptoms in the logistic regression (model 3) led to a sta- (Appelbaum et al. 2000) in which Mullen's (1997) princi- tistically significant result. TCO symptoms were signifi- pal objections regarding the definitions of TCO symptoms cantly related to high violence. most likely have been taken into account (table 1). Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 In another series of stepwise forward logistic regres- Therefore, it seemed necessary to reinvestigate the sion procedures, the influence of threat and control-over- position of the TCO symptoms (in a strict and narrow ride symptoms was analyzed separately (table 8). As the psychopathological definition; appendix 1) in schizophre- models 1 and 2 are identical with those in table 7, only the nia patients who committed a violent act leading to long- new models 3 (+ control-override symptoms) and 4 (+ term treatment in a forensic institution by comparison threat symptoms) are presented. One can see that the asso- with a control group of schizophrenia patients without a ciation between TCO symptoms and high violence in history of aggressive behavior. table 7 has to be ascribed primarily to the threat compo- The offender and the nonoffender groups did not dif- nent, while control-override has no statistically significant fer in age, age at onset, duration of illness, and schizo- effect. phrenia subtypes (table 2). Yet, as was to be expected, general criminogenic factors such as lower social class of Discussion origin (see Edwards et al. 1988; Farrington 1990; Wessely and Taylor 1991; Farrington and West 1993; Heads and The search for reliable predictor variables for future vio- Taylor 1997; Hiday 1997; Stueve and Link 1997; Swartz lence of mentally ill subjects is one of the most important et al. 1998; Kennedy et al. 1999) and substance-related topics of forensic psychiatry, not only because of the spe- disorders (see Eronen et al. 1996a; Monahan 1997; cial public interest, and the prejudices against and the RasSnen et al. 1998; Scott et al. 1998; Swartz et al. 1998; stigmatization of psychiatric patients, but also because of Wallace et al. 1998; Citrome and Volavka 1999; George the consequences on general mental health care (e.g., civil and Krystal 2000; Mullen et al. 2000) could be found commitment laws) (Miller 1993; Beck 1996; Beck and more frequently in the offender group, confirming the Wencel 1998; Schanda 1999, 2001). knowledge of an association between low social class of Table 7. Stepwise forward logistic regression models for risk of high-violence offending In male schizophrenia offenders Model 1 Model 2 Model 3 Social origin + Substance-related + TCO symptoms disorders Risk factors OR (95% Cl) OR (95% Cl) OR (95% Cl) High- (n = 68) vs. low- Social origin violence (n » 47) Substance-related offenders1 disorders TCO symptoms 10.08" (2.18-48.00) Model chi-square 0.33 1.07 11.96*" Note.—Cl = confidence interval; OR = odds ratio; TCO = threat/corttroJ-override. Parameter significance tests based on WakJ chi-square testwtth
Schizophrenia, Delusional Symptoms, and Violence Schizophrenia Bulletin, Vol. 30, No. 1, 2004 Table 8. Step wise forward logistic regression models for risk of high-violence offending In male schizophrenia offenders with separate Inclusion of threat and control-override symptoms Model 3 1 Social origin + Substance-related disorders + control-override Model 4 1 symptoms + Threat symptoms Risk factors OR (95% Cl) OR (95% Cl) High- (n = 68) vs. low- Social origin violence (n = 47) Substance-related offenders2 disorders Control-override symptoms Threat symptoms 6.78" (2.07-22.27) Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Model chi-square 1.37 12.11*" Atore.—Cl = confidence Interval; OR - odds ratio. Parameter significance tests based on WakJ chi-square test with df= 1. 1 Models 1 and 2 are Identical to those in table 7. 2 Seventy of offense rated according to Taylor (1985), total n - 115, In 4 cases definite classification not possible because of incompatibility with legal definitions. ** p < 0.01 ;*" p < 0.001 origin and violent/criminal behavior—the latter in concor- Hodgins et al. 1996 vs. Gottlieb et al. 1987; Eronen et al. dance with sociological theories regarding the suppression 1996a, 1996*, 1996c; see also Wallace et al. 1998), we of aggressive behavior by education in higher social subdivided our offender sample into those with high- and classes (Elias 1976; Bourdieu 1988). low-severity offenses according to Taylor (1985). And, in In table 3, one can see that TCO symptoms could be fact, the paranoid subtype is moderately but significantly registered in both groups very frequently during a 7-year overrepresented in the high-violence group, confirming course. Link and Stueve (1994), Link et al. (1998), and the aforementioned general knowledge (Bdker and Hafner Swanson et al. (1996, 1997) do not offer any information 1973; Eronen et al. 1996c), while the disorganized and the about the occurrence of TCO symptoms within the several residual subtypes showed an association with low vio- diagnostic subgroups. This is also the case in Appelbaum et lence (table 5). Sociodemographic factors and substance al. (2000). But, after combining the original sample descrip- abuse were not able to differentiate between the high- and tion (Steadman et al. 1998) with the number of TCO symp- the low-violence groups. toms at the time of index hospitalization (Appelbaum et al. In contrast to the lack of significance regarding the 1999), one can draw the conclusion that in the MacArthur differentiation of offenders and nonoffenders, TCO symp- sample 84.1 percent of the schizophrenia patients with sus- toms showed a statistically significant association with pected delusions (or 51.1% of all schizophrenia patients) high violence (table 6). While control-override symptoms had persecutory delusions in the weeks before index admis- were not able to discriminate between the high-and the sion; the rates for body/mind control were 75.4 percent and low-violence groups, threat symptoms were registered 45.8 percent, respectively. So, the frequency of TCO symp- significantly more often in the severely violent group. toms is comparable to that in our sample despite the differ- This was confirmed by multivariate statistics (table ent periods of registration (mean more than 7 years vs. 10 7). Only the inclusion of TCO symptoms (model 3) was weeks). However, there were no significant differences in able to ameliorate the model chi-square and to define the the occurrence of TCO symptoms in the offender and the high-violence group. Nevertheless, it must be kept in nonoffender groups (88.2% vs. 90.5%). mind that TCO symptoms were present also in 76.6 per- This is confirmed by a multivariate procedure that cent of the low-violence offenders (table 6), thus indicat- showed the importance of sociodemographic factors and ing a high false-positive rate. substance abuse for the discrimination between offenders The remarkably different frequencies of threat and and nonoffenders (table 4). control-override symptoms and the fact that only threat As it is known from the literature that the severity of symptoms but not control-override symptoms were signif- a violent act is positively correlated with the increasing icantly overrepresented in the high-violence offender influence of illness-related factors (see Lindqvist and group (table 6) suggest that there should be a separate Allebeck 1990; Swanson et al. 1990; Link et al. 1992; investigation of the influence of threat and control-over- 39
Schizophrenia Bulletin, Vol. 30, No. 1, 2004 T. Stompe et al. ride (table 8)—by all means in concordance with Link et patients), which points to the principal problem of data al. (1998). But, while Link et al. (1998) found both threat collection. Appelbaum et al. (2000) concluded that the and control-override to be independently associated with "reliance on subject self-reports of delusional symptoms violent behavior, our data confirmed such an effect for may result in mislabelling as delusions other phenomena only the threat component. that can contribute to violence" (p. 566), but it is an inves- However, the significance of our data is limited tigator's job to make the best possible attribution of a phe- because of a number of methodological limitations, which nomenon. The "unbiased" registration of a "symptom" also apply to the studies presented in table 1, with the suggests an increase in reliability but introduces a new exception of Appelbaum et al. (2000). First, the study bias that leads to a decrease in validity by neglecting the design is retrospective, which in general means a reduc- central problem: whether the patient and the investigator tion of validity. But one has to take into account that understand the question the same way (see also the results prospective studies on violent behavior over longer peri- of Klosterkotter et al. 1994). In the case of lay interviews, ods of time with repeated patient interviews suffer from the problem may be increased by deficits in the interview- the unavoidable bias that the investigation of the problem ers' knowledge of subtle psychopathological phenomena Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 per se is changing the outcome (Schanda and Taylor such as feelings of external control. So, especially for the 2001). assessment of CO symptoms, it is necessary to assess Second, the longer the periods of registration of vio- their presence more precisely by asking additional ques- lence and TCO symptoms, the more questionable the tions (appendix 1). causal connection between symptoms and violence (see This problem is illustrated by Link et al. (1998). From Taylor and Hodgins 1994). their data one can calculate that comparable items were Third, as proven by Steadman et al. (1998), agency registered in the same sample with remarkably different records represent only part of the total amount of violent frequencies depending on whether the SADS or the PERI behavior. Like all other studies on TCO symptoms, with was used: SADS "persecutory delusions" 0.4 percent vs. the exception of Appelbaum et al. (2000) and partly PERI "people wished to do harm very/fairly often" 7.3 Swanson et al. (1997), our study did not include a per- percent (plus "sometimes/almost never" 53.8%); SADS sonal interview of collaterals. Despite the fact that our "delusions of control" 1.4 percent vs. PERI "mind domi- control patients were asked about violent behavior in a nated by external forces very/fairly often" 2.2 percent nonstandardized way and all hospital files were checked (plus "sometimes/almost never" 16.8%), adding to the lat- for any indication of violence not officially prosecuted, ter the PERI item "thoughts put in head that were not the we cannot be certain that our "nonviolent" controls have patient's own" 4 percent ("very/fairly often") and 35.3 per- not been violent in the past. But one has to remember that cent ("sometimes/almost never"). Obviously, the lay- Europe's crime rates, cases solved, and nonalcohol sub- administered PERI is documenting—in contrast to the psy- stance abuse are quite different from those of the United chiatrist-administered SADS—the perception of a hostile States—especially regarding more severe forms of vio- environment in general without the obligatory presence of lence. The U.S. homicide rate, for instance, is four times severe psychopathology. This confirms the statement of that of the United Kingdom (Eronen et al. 19966)- The Appelbaum et al. (2000), who were able to replicate earlier same holds true for the number of cases solved (Eronen et findings "only by including a large number of presump- al. 1996*, 1997) and the extent of illicit substance abuse tively nondelusional symptoms under the threat/control- (Eronen et al. 1996c). So the possibility of a major bias override rubric" (p. 571). Taking all this into account, one seems rather low in our sample. has to doubt whether the meanings of the TCO symptom Fourth, the role of impulsivity was not sufficiently definitions in the Link and Swanson papers are really com- considerea1—quite apart from the fact that impulsivity in parable with those in the Appelbaum paper (table 1) or connection with acute psychotic symptomatology cannot with our own. In any case, it seems necessary to question a be automatically equalized with personality-based impul- positive as well as a negative answer of a patient, to ask sivity (Stompe and Ortwein-Swoboda 2000). for examples, and to insist on precise descriptions (appen- Fifth, the varying influence of the level of social dix 1). functioning of a patient on symptom-caused violence Regarding the insinuated "exceptional dangerous- (Swanson et al. 1998) and the role of social networks ness" of schizophrenia patients, we have concluded that (Estroff et al. 1994) have not been taken into account. control-override symptoms—if seen in concordance But, apart from all the methodological problems, the with the definitions for schizophrenia disorders and crucial question for the assessment of the validity of the affective disorders with mood-incongruent features in TCO symptoms for the prediction of violent behavior DSM-IV (APA 1994, pp. 275, 378, 381)—are not an seems to be their different meanings (for investigators and outstanding source of violence. Moreover, from the 40
Schizophrenia, Delusional Symptoms, and Violence Schizophrenia Bulletin, Vol. 30, No. 1, 2004 position of a clinical psychiatrist, one has to consider tion of violence on psychiatric wards. In: Hodgins, S., ed. that these symptoms are often rather volatile and brief Violence Among the Mentally III. Dordrecht, The and can be experienced by the patient also as neutral or Netherlands: Kluwer, 2000. pp. 237-250. positive (Stompe and Ortwein-Swoboda 2000). In con- Boker, W., and Hafher, H. Gewalttaten Geistesgestdrter. trast, delusional threat is for a patient an exclusively New York, NY: Springer, 1973. negative (ominous, dangerous) phenomenon. But threat Bourdieu, P. Die feinen Unterschiede. Kritik der is, compared to control-override, relatively unspecific gesellschaftlichen Urteilskraft. 2nd ed. Frankfurt/Main, and occurs—not only as "a generally suspicious attitude Germany: Suhrkamp, 1988. toward others" (Appelbaum et al. 2000, p. 571) but also as a clear delusional symptom—in schizophrenia as Brennan, P.; Grekin, E.; and Vanman, E. Major mental well as in affective, organic, substance-related, and per- disorders and crime in the community. A focus on patient sonality disorders. populations and cohort investigations. In: Hodgins, S., ed. Violence Among the Mentally 111. Dordrecht, The Netherlands: Kluwer, 2000a. pp. 3-18. Conclusion Downloaded from http://schizophreniabulletin.oxfordjournals.org/ by guest on May 13, 2015 Brennan, P.A.; Mednick, S.A.; and Hodgins, S. Major Our results confirm the importance of general factors such mental disorders and criminal violence in a Danish birth as substance abuse and social origin for the violent behav- cohort. Archives of General Psychiatry, 57:494-500, ior of schizophrenia patients. The TCO symptoms in a narrow, clinical definition were not associated with vio- BOhl, A. and Zofel, P. SPSSfUr Windows. Version 6.1. 2nd lence in general, yet they turned out to be an indicator of ed. Bonn, Germany: Addison-Wesley, 1995. pp. 328-335. the severity of an offense. This effect is primarily due to Citrome, L., and Volavka, J. Schizophrenia: Violence and the comparatively unspecific threat symptoms, whereas comorbidity. Current Opinion in Psychiatry, 12:47-51, control-override symptoms—at least in our definition typ- 1999. ical for schizophrenia—showed no significant association Cooke, D.J. Major mental disorder and violence in correc- with severe violence. Future research is needed to investi- tional settings. Size, specificity, and implications for prac- gate the complex interactions between psychotic symp- tice. In: Hodgins, S., ed. Violence Among the Mentally III. toms, underlying affect, impulsivity, social level of func- Dordrecht, The Netherlands: Kluwer, 2000. pp. 291-311. tioning, social networks, and violence. Edwards, J.G.; Jones, D.; Reid, W.H.; and Chu, Ch.-Ch. Physical assaults in a psychiatric unit of a general hospital. References American Journal of Psychiatry, 145:1568-1571, 1988. American Psychiatric Association. DSM-FV: Diagnostic Elias, N. Ober den Prozess der Zivilisation: and Statistical Manual of Mental Disorders. 4th ed. Soziogenetische und psychogenetische Unterschiede. Washington, DC: APA, 1994. Frankfurt/Main, Germany: Suhrkamp, 1976. Appelbaum, P.S.; Clark Robbins, P.; and Monahan, J. Eronen, M.; Hakola, P.; and Tiihonen, J. Factors associ- Violence and delusion: Data from the MacArthur ated with homicide recidivism in a 13-year sample of Violence Risk Assessment Study. American Journal of homicide offenders in Finland. Psychiatric Services, Psychiatry, 157:566-572, 2000. 47:403-406, 1996a. Appelbaum, P.S.; Clark Robbins, P.; and Roth, L.H. Eronen, M.; Hakola, P.; and Tiihonen, J. Mental disorders Dimensional approach to delusions: Comparison across and homicidal behavior in Finland. Archives of General types and diagnoses. American Journal of Psychiatry, Psychiatry, 53:497-501,1996fc. 156:1938-1943, 1999. Eronen, M.; Tiihonen, J.; and Hakola, P. Schizophrenia Beck, J.C. Forensic psychiatry in the USA and U.K.: A and homicidal behavior. Schizophrenia Bulletin, clinician's review. Criminal Behaviour and Mental 22(l):83-89, 1996c. Health, 6:11-27, 1996. Eronen, M.; Tiihonen, J.; and Hakola, P. Psychiatric disor- Beck, J.C, and Wencel, H. Violent crime and axis I psy- ders and violent behavior. International Journal of chopathology. In: Skodol, A., ed. Psychopathology and Psychiatry in Clinical Practice, 1:179-188, 1997. Violent Crime. Washington, DC: American Psychiatric Estroff, S.E.; Zimmer, C ; Lachicotte, W.S.; and Benoit, J. Press, 1998. pp. 1-27. The influence of social networks and social support on Bjorkly, S. High-risk factors for violence. Emerging evi- violence by persons with serious mental illness. Hospital dence and its relevance to effective treatment and preven- and Community Psychiatry, 45:669-679, 1994. 41
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