Research projects 2021 - Topics for Honours and MPH 24 point Dissertations - The University of Western Australia
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School of Population & Global Health Research projects 2021 Topics for Honours and MPH 24 point Dissertations
Research projects now available in the School of Population & Global Health (SPGH) As a world-class research university, UWA offers research opportunities of the highest calibre. You will work closely with an expert supervisor on a specific research topic to produce a manuscript of significant academic scholarship. Your initial research training can include completion of an Honours or a postgraduate coursework Master of Public Health (MPH) with a 24 point dissertation. This can lead to enrolment in a Master of Philosophy (MPhil) or Doctor of Philosophy (PhD). As an honours or 24 point dissertation research student with us, you will develop, under supervision, a paper for publication in a scientific journal - this is the first step in your research career! How does research training at SPGH work? You will work with an academic researcher Although some projects use linked data and to investigate an important and topical require a high degree of analytical aptitude, area of public health. Responsible, there are many other projects that require conscientious students, who meet the different skills. Given the scope of projects eligibility criteria, with well-developed available, a great project can be found to interpersonal and written communication match your own interests and skills. skills are sought for these projects. Want to know more? If you’re interested in an Honours or a MPH 24 point dissertation Contact our Honours & Dissertation Coordinator by email - karen.martin@uwa.edu.au uwa.edu.au 3
Research Areas & Centres at SPGH Our research strengths include a strong evidence-based approach to services and health program evaluation. We have a proven record of achievement in preventative, clinical and occupational epidemiology and have been instrumental in setting world standards in population health databases through record linkage. Cardiovascular Disease Epidemiology Aims to reduce the burden of cardiovascular disease through research into trends and determinants of acute events, treatment, management and outcomes. Centre for Health Services Research Is a leader in its field through its work with linked medical and health data and the evaluation of health services, patient safety, surgical care and pharmaco-epidemiology. Child & Adolescent Development and Health Early influences on child and adolescent health significantly impact on health and development outcomes throughout life. Our research draws on the skills and experience of our teams’ multi-disciplinary backgrounds to engage with stakeholders and deliver high quality research with real world policy and practice implications. Genetic Epidemiology Group Aims to identify the genetic and environmental determinants of common human diseases, and explore ways of using this information to improve human health. Global Environment and Health Investigates the relationships between ecosystems, environmental and occupational agents and health, at local and global scales, in order to determine ways that we can improve global human health. We research disease outcomes resulting from occupational and environmental exposures, such as mining hazards, asbestos, air pollution, heat, noise and water. We are also investigating the positive impact of green and blue spaces on health, and a developing area of interest is health promotion in relation to global and environmental health Health and Labour Economics To improve resource allocation and decision making in the health sector through systematic evaluation and assessment, with an economic perspective. The Raine Study - www.rainestudy.org.au/ The Western Australian Pregnancy Cohort (Raine) Study is one of the world’s largest successful prospective cohorts of pregnancy, childhood, adolescence and now early adulthood. These families have provided environmental, developmental and health information over the past 30 years offering a unique and valuable resource covering a wide range of health areas. Neuropsychiatric Epidemiology Research Unit (NERU) Focuses on psychiatric epidemiology, taking a cross-disciplinary approach to the study of psychotic disorders including schizophrenia and other severe mental illness. 4 The University of Western Australia
Vulnerable Groups Aims to improve health and social outcomes and reduce the disease burden among some of society’s most at-risk populations. Western Australian Centre for Road Safety Research (WACRSR) Has been established to conduct multi-disciplinary research, using a public health approach, into new and innovative approaches to road safety in Western Australia to reduce death and serious injury on Western Australian roads. Western Australian Centre for Rural Health (WACRH) - www.wacrh.uwa.edu.au/ Aims to improve rural, remote and Aboriginal health through research, education, student support and community service activities. WACRH operates with funding from the Commonwealth Department of Health and support from the University of Western Australia but also works closely with numerous health organisations, on a local and national level. Contact information for SPGH Coordinating Supervisors (listed under each project title): Professor Angus Cook A/Professor Monica Moran angus.cook@uwa.edu.au monica.moran@uwa.edu.au Professor Tom Briffa Professor Vera Morgan tom.briffa@uwa.edu.au vera.morgan@uwa.edu.au Dr Hayley Christian Dr Kevin Murray hayley.christian@uwa.edu.au kevin.murray@uwa.edu.au A/Professor Justin Denny Dr Lee Nedkoff justin.denny@uwa.edu.au lee.nedkoff@uwa.edu.au Professor Colleen Fisher Professor David Preen colleen.fisher@uwa.edu.au david.preen@uwa.edu.au Dr Peter Franklin A/Professor Rohan Rasiah peter.franklin@uwa.edu.au rohan.rasiah@uwa.edu.au Dr Michelle Fraser A/Professor Paul Roberts michelle.fraser@uwa.edu.au paul.roberts@uwa.edu.au Professor Jane Heyworth jane.heyworth@uwa.edu.au A/Professor Frank Sanfilippo frank.sanfilippo@uwa.edu.au Dr Siobhan Hickling siobhan.hickling@uwa.edu.au Dr Julie Saunders julie.saunders@uwa.edu.au A/Professor Judith Katzenellenbogen judith.katzenellenbogen@uwa.edu.au Professor Linda Slack-Smith linda.slack-smith@uwa.edu.au Dr Matthew Legge matthew.legge@uwa.edu.au A/Professor Jennifer Stone jennifer.stone@uwa.edu.au Dr Ian Li ian.li@uwa.edu.au Professor Sandra Thompson sandra.thompson@uwa.edu.au Dr Karen Martin karen.martin@uwa.edu.au uwa.edu.au 5
The Busselton Health Study The Busselton Health study is a series of disorders, gastrointestinal, kidney and liver internationally recognised cross-sectional diseases, cancer, obesity, sleep disorders, and longitudinal population health studies cognition and genetic epidemiology. carried out on the population of Busselton, Extensive information on demography, Western Australia which aims to provide a lifestyle and behaviour have also been better understanding and management of collected at each of the surveys along with disease and illness. blood samples for biochemical measures Research activities undertaken as part of and genetic studies. the Busselton Health Studies are diverse Epidemiological data analysis driven and encompass a wide range of health projects are available for Honours and conditions and measures. Masters students, and interested students These have included cardiovascular disease, should contact Dr Kevin Murray for details. respiratory disease, diabetes and endocrine Projects under the Cardiovascular Research Group State-of-the-Art Cardiovascular • Monitoring coronary artery disease Disease (CVD) Research • Management of CVD in the Indigenous Prof Tom Briffa population • Diabetes and CVD Background: CVD is costly and prevalent • Peripheral arterial disease worldwide. Monitoring and reporting trends • Risk Factor Prevalence Study is a national priority health area and is a • Coronary artery revascularisation driver of health policy aimed at improving • Chronic kidney disease and CVD healthcare delivery and outcomes Methodology: The Cardiovascular Outline: Various projects in specific areas Research Group uses clinical data collected are offered. These will involve examining from cohorts in Western Australia together the trends and models of care in CVD with person linked administrative data prevention, treatment and management and from hospitals and registers to examine may consider clinical epidemiology, health influences, trends and epidemiology of CVD outcomes, pharmacotherapy, prevention, health outcomes. cost-effectiveness and community engagement. A range of topic areas include: • Atherothrombotic disease across the vascular territories • Busselton Health Study 6 The University of Western Australia
Processing evaluation of the Developing contemporary Healing Right Way trial algorithms for monitoring A/Prof Judith Katzenellenbogen myocardial infarction in Australia Dr Lee Nedkoff Background: This project is part of a process evaluation of the NH&MRC-funded Background: Measuring population randomised control trial (RCT) entitled trends in myocardial infarction (MI) ‘Enhancing rehabilitation for Aboriginal incidence and hospitalisation rates has Australians after brain injury: Healing Right been an important historical indicator Way’ (HRW). This project is focused on of the effectiveness of coronary disease providing culturally secure rehabilitation services for Aboriginal patients with prevention. However, the use of new acquired brain injury. HRW uses a diagnostic biomarkers since the 2000s has randomised cluster step-wedge design impacted epidemiological monitoring of of a complex intervention (consisting temporal trends in MI. of culturally secure training (CST), and the introduction of an Aboriginal Brain Outline: The study will quantify the Injury Coordinator (ABIC) role) in four impact of changes in cardiac biomarkers metropolitan and four regional Western on trends in MI, and test the feasibility Australian hospitals. of linking cardiac biomarker data to We have designed and implemented a population-level hospitalisation data for mixed methods process evaluation which is ongoing monitoring of MI in Australia. being undertaken both prospectively and retrospectively, enhancing the conduct and Methodology: A linked dataset interpretation of the parent study. containing hospital, emergency department, mortality and pathology data Outline: To determine processes, barriers for all coronary heart disease presentations and facilitators that have influenced the in Western Australia since 2000 is available. implementation of the trial and ongoing Classification of MI and each coronary heart partnerships with stakeholders during the disease subtype will be made according to first two years of the RHW. ICD-coding and cardiac biomarkers, and Methodology: Qualitative study using rates and trends compared across each data collected prospectively as part of the classification group. process evaluation. Project Specific Requirements: Data collected includes minutes of Knowledge of evaluation frameworks, meetings, interviews with project staff, qualitative methods. surveys with participants of cultural security training in hospitals, review of communication with project partners. Project Specific Requirements: Knowledge of evaluation frameworks, qualitative methods. Project Length: 24 point MPH only uwa.edu.au 7
The epidemiology and experience Examples: of rheumatic heart disease • Analysis of concurrent ARF/RHD and (End RHD in Australia: Study of obstetric/pregnancy hospitalisations. Epidemiology – ERASE project) • Missed opportunities in the diagnosis of A/Prof Judith Katzenellengbogen ARF in hospital (review administrative records of ARF/RHD diagnosed patients Background: Acute rheumatic fever to identify whether ARF had not been (ARF) and rheumatic heart disease (RHD) diagnosed in previous emergency persist as significant sources of health department and hospital encounters. burden among Indigenous Australians. End • Collection and analysis of ARF/RHD RHD in Australia: Study of Epidemiology paediatric cardiology out-patient data (ERASE) Project aims determine the over 20 years. baseline burden of ARF/RHD in Australia • Descriptive study of PHC data of patients and to develop further insights into the diagnosed with ARF/RHD in NT. progression and outcomes of the disease • Development/evaluation of resources for as a basis for improved monitoring. Other dissemination of findings to Aboriginal areas of investigation include health communities (mixed methods). system costs, hospital service utilisation, • Qualitative studies of aspects of the medication adherence and factors affecting management and experiences of ARF/ the management of these conditions in RHD. primary care. • Development of a standardized set Outline: A number of potential projects of recommended data items that associated with the ERASE project facilitate comparability of RHD-related are available for students, including information in pregnant women from epidemiological analyses and analyses varied sources and for various purposes related to health systems. Translation of (Delphi method). findings will occur through the End RHD Coalition as well as dissemination of results Project Specific Requirements: to communities. • For linked data analysis, competence in SAS; R or SPSS or preparedness to learn Methodology: The project uses a quickly. multi-jurisdictional linked database from • For evaluation and mixed methods multiple sources (hospital, primary health research, preparedness to learn care, deaths, RHD register) as well as qualitative methods. qualitative data on primary care systems to support RHD management. Midwives data is currently being linked in as well. An appropriate methodology will be developed depending on the research question, available data and the level of skill/interest of the student. 8 The University of Western Australia
Pharmacoepidemiology studies Analysis will require identifying the using the 10% PBS sample specific drug groups of interest, applying A/Prof Frank Sanfilippo multivariable regression methods, estimating medication adherence using the Background: We have applied to proportion of days covered (PDC) method, obtain a 10% sample of data from the describing patient characteristics, and Pharmaceutical Benefits Scheme (PBS) with simple univariate and bivariate statistics. linkage to deaths. The dataset will provide a There is potential to publish the findings in a longitudinal source of records for medicines suitable journal. dispensed in Australian pharmacies from 2012 onwards. This will allow various Project Specific Requirements: analyses on use of medicines in Australia. Knowledge of medicines and therapeutics would be an advantage, although an Outline: To investigate the use of specific interest in this area would be sufficient, groups of medicines in a 10% random with additional training provided. Analysis sample of patients receiving medicines will require use of multivariable regression through the PBS in Australia. methods. The data are linked and some Methodology: The PBS data contains knowledge or understanding of how to information on medicines dispensed handle these data would be useful. from Australian pharmacies, including hospital pharmacies that are registered Project Length: 24 point MPH only with the PBS (ie. all private and some public hospitals). Variables include age, sex, name and strength of the drug, quantity dispensed, ATC code, PBS item code, date of supply, date prescribed, beneficiary status (concession card, general beneficiary) and date of death. The dataset will be supplied on approval by the Department of Human Services. It consists of linked data of PBS records and matching death record from a random 10% sample of people in Australia. Various analyses can be completed using these data, with specific examples including: (i) use of psycho-active medicines in the elderly; (ii) use of low dose vs high dose statins by patient characteristics; (iii) patterns of medication use before and during the COVID-19 period (eg. supply of hydroxycholoroquine); (iv) use of medicines in the very old; (v) adherence of specific drug groups (eg. anti-retroviral drugs, statins, beta blockers, antiplatelet agents). uwa.edu.au 9
Projects with the Centre for Health Services Research Linking for Life: Enhancing across government sectors; and pathways to well-being for all 3. Identify factors associated with Australians resilience in disadvantaged groups to Prof David Preen; Dr Rebecca Glauert improve intergenerational outcomes. Background: The Linking for Life Project Methodology: The sub-projects will identify pathways to wellbeing and developed under this program of work will better social outcomes across the life- utilise up to 40 years of whole-population, course for high-risk/vulnerable individuals genealogically linked data, across seven and their families to streamline service government departments including the provision, improve outcomes and identify WA Dept. of Communities, Dept. of Justice, cost-efficiencies across government WA Police, Dept. of Education, Dept. of agencies. The work will expand cross- Health, Mental Health Commission and the sectoral data linkage capability, enhancing Commonwealth Dept. of Education and research capacity to generate evidence- Training. based policy to improve integrated service Statistical analysis and multivariate delivery across government. modelling of these data will be undertaken The project involves the analysis using SPSS, Stata or SAS to address the of longitudinal, whole-population, above-mentioned research aims. genealogically linked data, across seven Project Specific Requirements: government departments in order • Knowledge of epidemiology and determine pathways (across individual, biostatistics. family, community and system levels) that • Completion of PUBH5785 Introductory reduce vulnerability to adverse outcomes Analysis of Linked Health Data or equivalent including social disadvantage, child prior experience. abuse and neglect, mental illness, poor • Experience with writing statistical syntax educational attainment, justice system to complete data analyses. involvement, and restricted access to public services. Project Length: 24 point MPH only Outline: Research questions in this project are categorised under three Exploring the Mental Health and intersecting domains: 1) Resilience and Emotional Wellbeing of Reception overcoming disadvantage; 2) Families and Prisoners Intergenerational Effects; and 3) Aboriginal Prof David Preen; Mr Craig Cumming Wellbeing, with the primary aims of the Background: People who go to prison current program being to: experience social disadvantage, mental 1. Determine pathways that reduce illness and trauma at far higher rates the vulnerability to adverse outcomes and general community. To investigate mental restricted access to public services; illness and emotional wellbeing in this 2. Identify critical transition points to target group further 719 adults were recruited prevention and intervention strategies 10 The University of Western Australia
and interviewed within one week of A main project aim is to provide high entering prison. They were asked a range of quality data that will assist in the planning questions on topics that included mental and provision of mental health services to health, life stressors, drug and alcohol use, mentally disordered offenders both within and unmet needs. the criminal justice system and in the community. Outline: The project aims to describe and quantify the nature and extent of Methodology: Cross sectional survey mental disorders including alcohol and data collected within one week of reception substance misuse disorders amongst WA into prison. reception prisoners, as well as their met Project Specific Requirements: and unmet needs. Reasonable knowledge of biostatistics Projects under Child and Adolescent Health Children’s Physical Activty, Health Project Specific Requirements: and Development • Ability to conduct quantitative research. Dr Hayley Christian • Excellent writing skills. • Statistical analysis (SPSS and/or SAS). Background: This research forms part • Ability to work as part of a team. of the PLAYCE program of research – Places • Good interpersonal communication Spaces & Environments for Children’s skills. Physical Activity. PLAYCE examines the longitudinal influence of the physical, Physical activity policy for early social and policy environment on young childhood education and care- children’s physical activity, sedentary parent engagement behaviour, eating behaviour, weight status, sun exposure and development: at home, Dr Hayley Christian around the neighbourhood and whilst Background: Daily physical activity is attending early childhood education and critical during the early years of life for care (ECEC) or school. This research will facilitating children’s health and provide information on how best to create development. Only one in three Australian healthy environments to support young children aged 2 to 5 achieve the children’s wellbeing and development. recommended level of three hours of daily physical activity. Early childhood education Outline: To determine the patterns of and care (ECEC) services are a key setting to movement behaviours (physical activity, intervene to increase physical activity. sedentary time and sleep) in young children across early childhood (2-7 years) Outline: The student will be part of a and the impact on weight status and multi-jurisdictional NHMRC funded project developmental outcomes. and have the opportunity to work with eight partner agencies. The project will provide Methodology: Quantitative analysis of n-depth knowledge about parents’ barriers existing PLAYCE cohort data. and enablers for improving parent-child, uwa.edu.au 11
and parent-educator engagement around Methodology: Literature review; children’s physical activity. Qualitative; Quantitative survey. This will involve exploring, identifying and Project Specific Requirements: better understanding the factors that • Ability to conduct quantitative/ strengthen the educator-parent qualitative research. engagement process to boost children’s • Excellent writing skills. physical activity in the home and ECEC • Statistical analysis (SPSS and/or SAS). environment. • Ability to work as part of a team. Methodology: Literature review; • Good interpersonal communication Qualitative. skills. Project Specific Requirements: • Ability to conduct quantitative/ qualitative research. Increasing children’s physical • Excellent writing skills. activity through family dog • Ability to work as part of a team. walking and play • Good interpersonal communication Dr Hayley Christian skills. Background: This research forms part of the PLAYCE program of research – Places Spaces & Environments for Health benefits of natural Children’s Physical Activity. The PLAYCE outdoor environments PAWS Study aims to trial different methods Dr Hayley Christian of encouraging more physical activity in Background: Natural outdoor children through playing and walking with environments including blue spaces help the family dog. reduce stress, promote physical activity Outline: The aim is to see whether and social connections, improve overall active play and walking with the family health and well-being, improve connection dog facilitates improved developmental to place and reduce urban heat effects. The outcomes in young children. health benefits associated with exposure to blue space (oceans, rivers, lakes etc) likely Methodology: Quantitative analysis of follow similar pathways and mechanisms to existing pilot study data. those identified for green space. Project Specific Requirements: • Ability to conduct quantitative research. Outline: This research will determine the • Excellent writing skills. health benefits of blue space. It will involve • Statistical analysis (SPSS and/or SAS). stakeholder interviews and or intercept • Ability to work as part of a team. surveys to investigate how Western • Good interpersonal communication Australians access and use different types skills. of blue spaces in their community and what the health and wellbeing benefits are (and potential negative effects)? 12 The University of Western Australia
Testing the capacity of an We now have a dataset from these pilot online tool to promote safe sun studies that needs to be analyzed. behaviours in teenagers Project Aim: To pilot test a prototype Dr Hayley Christian; Shelley Gorman app that aims to improve the knowledge (Telethon Kids Institute - shelley.gorman@ and behaviours that young adolescents telethonkids.org.au) have around safe sun protection and exposure practices for vitamin D. Background: In this project, we have developed and are testing a prototype app Methodology: In school- and that aims to improve the knowledge and community-based pilot studies, we behaviours that young adolescents have will test end-user responses (‘process’: around safe sun practices for vitamin D. Our engagement, functionality, aesthetics and rationale for developing this app, was that: information quality) to using the app, as - A fun, educational online tool, when well as its capacity to improve their safe sun developed with adolescent ‘co-researchers’ knowledge and behaviours. would be useful and relevant; - It would more likely be accepted by Specific methodological approaches: adolescents than currently available tools; 1. Assess responses to questionnaires on and, ‘process’ outcomes related to using the - It would help them make better decisions developed app; about their health needs for protection 2. Assess the knowledge gain related to sun from excessive sun exposure and for health outcomes in response to using the sufficient vitamin D. app, compared with placebo control; and 3. Measure skin type, sun sensitivity We first recruited young adolescent co- and normal sun exposure patterns of researchers for their input into the design participants and sun exposure behaviours. of the app, along with other stakeholders, including those from Cancer Council Project Specific Requirements: WA, academics and eHealth technology The student will help the research team to: developers. We then co-developed a digital construct databases of survey data; collate wireframe which was first tested in a series and clean datasets; perform statistical of workshops with young people. We used analyses; perform qualitative analyses feedback from these workshops, design of feedback; critically analyze findings; guidelines of the wireframe (including and, write a manuscript that describes basic information, format, strategy and language), and ongoing input from co- and critically discusses study findings researchers and the research team to for publication. Essential skills for this develop the prototype app. Finally, we project include excellent written and oral conducted pilot studies to obtain end-user communication, very good organisation, responses (engagement, functionality, motivation and dedication. If accepted aesthetics and information quality) on for the project, the student will need to the developed app, testing its capacity complete police and working with children to improve the sunhealth knowledge and checks, which will be funded by the study. behaviours in an independent cohort of young adolescents (aged 12-13) via blinded Project Length: 24 point MPH only placebo-controlled interventions. uwa.edu.au 13
Reducing and preventing energy Project Specific Requirements: drink intake in children • Excellent interpersonal, written and oral Dr Siobhan Hickling; Dr Gina Trapp communication skills. • Working with Children Check. Background: Energy drinks have • Police Clearance. catapulted to popularity among young people. Whilst they are marketed to improve the body’s performance, they pose a significant health risk due to the Influence of the food environment high levels of caffeine, sugar, sodium and near schools on children’s dietary herbal stimulants they contain. In Australia, intake energy drinks are required by law to carry Dr Siobhan Hickling; Dr Gina Trapp a warning statement that they are ‘not Background: Many WA schools, recommended for children’, however especially in socio-economically no restrictions are placed on who can disadvantaged areas, are surrounded by purchase these drinks and they are widely unhealthy food-outlets. Recent calls from available and accessible to children. More the WA community for a ban on fast-food than half of energy drink consumers aged outlets near schools, further highlight the 12-17 years have reported experiencing need for regulation addressing the location adverse health outcomes following of unhealthy food-outlets, yet little is known consumption, some serious enough to about how often school children patronise warrant seeking medical help. Despite food-outlets near schools, when and what growing community concern and evidence they purchase. This lack of evidence means of health risks, Australian governments policies to manage food-environments near have not enforced age-specific restrictions WA schools are currently non-existent and on these drinks. Thus, there is a critical difficult to advocate for. need to identify other ways to minimise harm to children. Outline: Several multidisciplinary and innovative research projects are available. Outline: The overall aim of this These are aimed at: research is to develop knowledge-based • Longitudinally mapping, measuring interventions that could be effective and monitoring the food environment in reducing and preventing children’s surrounding Perth schools. energy drink intake. Two student projects • Investigating students’ patronage of can be offered; (i) the development of food outlets near their school, including a child-focused intervention and (ii) which food outlets they use, how often, the development of a parent-based when and what they purchase. intervention. • Identifying differences in the dietary intake of students attending schools Methodology: Focus groups with located in ‘healthy’ versus ‘unhealthy’ parents/children and development of food environments. intervention resources. • Undertaking natural experiments (before and after studies) to investigate how new food outlets opening near a 14 The University of Western Australia
school impacts on the eating behaviours The Youth Mental Health team at Telethon of children attending that school. Kids Institute is working on improving • Investigating student, school staff, the the mental health and wellbeing of community and food business owners’ LGTBIQA+ young people. We have several attitudes towards (a) unhealthy food opportunities to conduct research and environments near schools; and (b) translation projects on the mental health potential policy and practice changes of LGBTIQA+ young people and suicide to improve food environments near prevention initiatives with LGBTIQA+ young schools. people and their families. • Co-developing a research translation tool for Local Governments to better Outline: The project can focus on a manage food provision near schools. specific subgroup of LGBTIQA+ young people (e.g. trans young people), or Methodology: Depending on the LGBTIQA+ young people broadly. Students project chosen, methodologies could are able to work on one of the projects include use of Geographical Information already underway in our team, or create System (GIS) technology, direct a new project, depending on the specific observation, survey development (including degree requirements. The specific project an in-built interactive mapping activity), will depend on the interest and skills of the focus groups and interviews. student and our projects are flexible based Project Specific Requirements: on the student’s time frame. • Excellent interpersonal, written and oral Potential new projects are: communication skills. • Creating an intervention or enhancing • Working with Children Check. understandings on how to decrease suicide • Police Clearance. risk in LGBTIQA+ young people • Data analysis and qualitative research • Translating research to the real world skills (depending on the project chosen) through advocacy and policy change: for example, creating and piloting translational resources enhancing understandings of Improving the mental health of LGBTIQA+ young people, e.g. resources LGBTIQA+ young people targeted towards peers, families or Prof Angus Cook (in partnership with clinicians, or creating co-designed Penelope Strauss and Ashleigh Lin from the resources with trans young people on Telethon Kids Institute) navigating health services • Projects with parents or families of Background: LGBTIQA+ young people LGBTIQA+ young people, or clinicians who experience poorer mental health outcomes work with LGBTIQA+ young people and higher rates of suicidality compared to • A project within a broader longitudinal their non-LGBTIQA+ peers. It is also known project underway that is looking at the that LGBTIQA+ young people experience mental health and wellbeing outcomes of barriers in accessing health services trans people undergoing top surgery inclusive of LGBTIQA+ identities. uwa.edu.au 15
Methodology: To be discussed based • Appreciation and acceptance of diversity on the specific student and their interests and equality of all people, regardless of and needs. Our team conducts quantitative, age, gender, sexuality, race or religion. qualitative and mixed methods research. • Excellent written and verbal communication skills. Project Specific Requirements: • Demonstrated ability to work both • Requires a Working with Children Check independently and as a member of a • Undergraduate degree in health team. sciences. • Ability to work with young people and passion for the mental health of young people. Projects under the Genetic Epidemiology Group The Genetic Epidemiology Group (GEG) Projects with a genetic focus will use is home to a highly-skilled team of statistical methods of genetic and genomic genetic epidemiologists, statisticians and analysis, utilizing bioinformatics and epidemiologists who are committed to high throughput ‘omics’ technologies to identifying the genetic, epigenetic and unravel the genetic and environmental environmental determinants of common contributions to human disease. human diseases, and exploring ways of using such information to improve human Other projects involve high-level statistical health. analysis of “big data” from large data linkage projects or population-based The GEG team undertake research into a databases that focus more on (non-genetic) wide spectrum of human trait and disease clinical outcomes, integral to primary areas, as well as methodological research prevention as well as early detection of into the techniques required to conduct chronic human disease. successful projects. We work closely with clinical and academic collaborators locally, Projects are available for both Honours nationally and internationally. and Masters level projects. Previous biostatistics training is preferred. Research topics include: Interested students should contact A/Prof • Breast cancer Jennifer Stone for details and to be put in • Melanoma touch with relevant GEG team members • Mesothelioma and project supervisors. • Cardiovascular disease • Sleep disorders • Burns and scarring • Autism • Lipidomics • Statistical research methods 16 The University of Western Australia
Projects under Global Health In addition to the projects listed there may also be opportunities to get involved with research projects in northern Thailand. One potential topic is a SinLek rice project which is a placebo-controlled cross-over trial of a heritage black rice vs a white rice in a primary school in Chiang Rai, Thailand. Any students interested in undertaking a project in this area please contact A/Prof Justin Denny. Chronic kidney disease in Sri Outline: Lanka • Is drinking harvest rainwater associated Prof Jane Heyworth in collaboration with with a reduced risk of CKD? Dr Tanuja Ariyananda (Lanka Rain Water • Are the symptoms of CKDu improved Havesting Forum) and Dr Gayan Bowatte among patients drinking rain water? (University of Peradeniya) • What factors in drinking water sources Background: might lead to differences in risk? There are approximately 70,000 estimated • What are other potential risk factors for CKD/CKDu patients in 6 of the 9 provinces in CKDu? Sri Lanka. Despite many studies conducted Methodology: in this area, the risk factors for this disease Establish/undertake a case control study of are still uncertain (thus “u” in CKDu). CKD in Sir Lanka. According to studies carried out to date, 1. Identify methods for selecting cases and CKDu maybe a result of drinking water control . contamination. 2. Develop survey instruments for In the Northern province, a preliminary assessing exposure to water and other risk survey conducted of CKDu patients in factors. households with rain water harvesting 3. Monitor water quality of different water system installed in the northern province sources ( RW, RO, well) indicated that the patients “feel healthier” Project Specific Requirements: after drinking rain water and that their Good performance in epidemiology and condition remain stable. However, further biostatistics units. research is needed to confirm these findings and to identify differences in the constituents of harvested rainwater and other drinking water. The Lanka Rain Water Harvesting Forum (LRWHF) has installed over 500 RWH systems in households Northern & Uva province. uwa.edu.au 17
Migration widows: The impact Methodology: of the international migration We have undertaken qualitative research of workers on those who stay with women whose partners have behind migrated for work and the current study Dr Julie Saunders; Prof Jane Heyworth will build upon those findings to develop a questionnaire. Background: Nepal has a long history of labour migration with an estimated A quantitative survey of 100 women 3.5 million Nepalese working abroad who have a child aged under 5 will be (Simkhada et al 2017). Labour migrants undertaken. The sample will be stratified from Nepal are predominantly males; 15% on the basis of whether a partner has of all economically active males (aged migrated for work in the past 12 months. A 15 years and older) compared with 2% of sub-sample of 50 women will participate in Nepali females (Maharajan, Bauer, Kner, a test-retest reliability study completing the 2012). The majority of these males are from questionnaire on two separate occasions, agricultural backgrounds. two to three weeks apart. Despite research into the health risks The student will be supported by a local for those who migrate for work, there research assistant to recruit the sample and is little research on the health and administer the questionnaire. The student wellbeing impacts for those who stay will analyse and interpret the data and write behind. However, an understanding the up these findings. The student will prepare contextualised impact on women and a report the findings to be provided to the families left behind is important. NGOs, prepare a video of the key messages of this research and a conference abstract. Outline: To estimate the extent of social, health and gender impacts of the The student will analyse the transcribed international migration of male workers interviews, undertake thematic analyses, from Nepal on the women and families left and interpret and write up these findings. behind. The student will prepare a report the findings to be provided to the NGOs, Specific objectives are to: prepare a video of the key messages of this • Develop a questionnaire based upon the research and a conference abstract. results of recent qualitative research. • Pilot the questionnaire with 100 women Project Specific Requirements: in the Central (Kathmandu) and Western UG: Completed PUBH2203 and PUBH3305 (Pokhara) Development Regions in (or their equivalent) with a Distinction or Nepal. High Distinction grade. • Undertake a reliability study with a sub- PG: Completed PUBH4401 and PUBH4403 sample of this population. (or their equivalent) with a Distinction or • Estimate and compare the prevalence High Distinction grade. of key impacts among those left behind with those whose partner has not migrated for work 18 The University of Western Australia
Developing an mHealth Methodology: intervention to promote The student will work with DPHO and antenatal health and Kanchan Nepal to determine the schedule immunisation for delivery of health messages and seek Dr Julie Saunders; Prof Jane Heyworth their input into the appropriate style of message. The project may include Background: mHealth initiatives are interviews with staff of the DPHO and becoming more prominent in low and community health posts as well as focus middle income countries as a means groups with rural community members. of engaging residents in public health The student will prepare a project plan for activities. The Kaski District Public Health the mHealth intervention that includes Office (DPHO), located in Pokhara, Nepal recruitment, access, messages and ongoing wish to develop more effective ways or longer-term evaluation. of delivering health reminders around antenatal care and vaccinations to persons Project Specific Requirements: living in rural Nepal. Mobile phones are UG: Completed PUBH2216 or PUBH3302 (or commonly used in Nepal, thus mHealth their equivalent) with a Distinction or High initiatives may be an efficient method Distinction grade. of reaching families living in rural areas. PG: Completed PUBH5754 or PUBH5805 (or DPHO and Kanchan Nepal, our partner their equivalent) with a Distinction or High organization, will provide advice on the Distinction grade. local context, including antenatal care and immunisation schedules. Outline: To develop a culturally relevant mHealth intervention to convey specific health messages to rural Nepalese women. Specific objectives are to: • Review the literature on the use of mHealth interventions for health messaging. • Determine the messages that might be most effectively conveyed by this approach. • Develop culturally appropriate and engaging messages with input from the local community. • Pilot and evaluate the health messages for the app among the local community. uwa.edu.au 19
Projects under Global Environment and Health Health risk assessment of 3. Investigate the changes in hazards and artisanal brick kilns in low-and exposure levels with the implementation of middle-income countries ‘improved’ kiln technologies; and Prof Jane Heyworth 4. Investigate the implementation of ‘improved’ kiln technologies in the Background: The artisanal brick kiln Kathmandu Valley since the Nepal industry is an important source of air earthquake of April 25, 2015. pollution in low to middle income countries. In addition brick workers are among the Methodology: most marginalized of unskilled workers The project will require you to: and the industry is in need of urgent • develop, prepare and submit a research environmental, occupational health and proposal; safety interventions. There are over • review the literature on artisanal brick 300,000 highly polluting brick kilns kilns in low-middle income countries; throughout low- and middle-income • conduct a qualitative health risk countries, emitting over 890 million tonnes assessments based on analysis of the of CO2 each year as well as high levels of PM available literature; 2.5, sulfur dioxide, carbon monoxide and • obtain and compile available black carbon. These emissions are information on brick kiln reconstruction responsible for serious impacts on human in the Kathmandu valley since April 2015; health in workers and residents of • prepare manuscripts for publication. surrounding areas. Project Specific Requirements: This project will involve describing the Well-developed literature searching and global artisanal brick industry and the reviewing skills. associated risks to human health, and estimating the potential reduction in health risks with the implementation of ‘improved’ kilns that have been developed to reduce adverse environmental emissions. A case study of post-earthquake brick kiln reconstruction in Kathmandu valley will be undertaken. Outline: 1. Describe the artisanal brick kiln industry from a global perspective; 2a. Identify the hazards associated with artisanal brick kilns and the associated health and environmental outcomes for particular levels of exposure; 2b. Identify the exposed population and the potential for prevention; 20 The University of Western Australia
Health effects of air pollution What is the impact of vegetation Prof Jane Heyworth on air quality? Prof Jane Heyworth; Ania Stasinska; Dr Background: Air pollution (AP) patterns Natasha Pauli (School of Agriculture and have changed as technological advances Environment UWA) and pollution controls have led to reductions in concentrations of pollutants Background: There is emerging such as lead and sulfur dioxide (SO2). evidence that green space is associated However, urbanisation with its associated with health and wellbeing. Some of the increase in motor vehicles, industrial mechanisms by which this might occur processes and energy requirements, are include: increased physical activity, overtaking the advances made in AP control reduced stress, improving air quality and over the past two decades. The AP health reducing urban heat effects. Vegetation burden is substantial; there is evidence may be both beneficial and harmful for air from Europe that ~50% of adult mortality quality as trees can filter out particulates resulting from AP is attributable to traffic in air, but some may also produce volatile emissions. Significant sources of AP in organic compounds or pollens. In order to the Perth metropolitan area are motor plan greening in urban areas to improve vehicles and domestic wood heaters (25% health more in-depth knowledge is needed of households have wood heaters). The aim regarding the specific settings and greening of this study is to investigate the long-term characteristics that will maximize benefits. effects of air pollution, specifically PM10, Outline: To understand the relationship PM2.5, NO2, CO and ozone, on cancer between green space and air pollution in outcomes in a cohort of older men in Perth. Australian urban environments. Outline: Does exposure to air pollution Methodology: Literature review. at the concentrations observed in Perth lead an increased risk of cancer. Project Specific Requirements: Good analytical and writing skills Methodology: Quantitative methods. AP exposure metrics have been developed and linked each participant in the Health in Men Study (HIMS), a cohort of 12,201 men aged 65 years and above. These men were recruited in 1996 and were followed up to 2016. Using cox proportional hazard regression models, the hazard ratios and 95% confidence intervals for the impact of different pollutants and cancer outcomes will be estimated. Project Length: 24 point MPH only uwa.edu.au 21
Health and well-being impacts Project Specific Requirements: of interactions with green space: Good analytical and writing skills. Ability Does perception of biodiversity and willingness to interact with members of influence outcomes? the public and/or key external stakeholders. Prof Jane Heyworth; Dr Natasha Pauli (School of Agriculture & Environment UWA) Modelling 20 years of noise in WA Background: Perth is within a global mines: have noise levels reduced? biodiversity hotspot, with a high proportion Dr Peter Franklin; Prof Jane Heyworth of endemic species coupled with a dramatic reduction in total area covered in native Background: Prolonged exposure to vegetation. There exists a broad body of high levels of noise can result in permanent literature detailing the links between green and irreversible damage to hearing (noise space and impacts on physical and mental induced hearing loss – NIHL). Noise health and wellbeing. However, there is exposure is prevalent in mining and is a a relative lack of information on how the generic hazard, to a greater or lesser extent, biodiversity of green spaces is a) perceived to all operations within mining. The mining by the general public and b) is linked with industry has long been known to have one health and well-being. of the highest rates of occupational NIHL. A 2004 SafeWork Australia report used Emerging research has shown some potential correlations between access to compensation claims (1998/99 to 2001/02 areas with higher biodiversity, respiratory data) for NIHL to determine incidence of health and allergic conditions. However, claims for different industries. Mining had the degree to which people’s perception the highest incidence of deafness claims of biodiversity influences their use and (343/100,000 employees in 2001/02). In opinion of green spaces with varying Western Australia (WA) there is a regulatory levels of native biodiversity has been little requirement for specific action to be taken explored in the Australian context. when people are exposed to either an average noise level of more than 85 dB(A) This research project will use a mixed for an eight-hour working day (LAeq,8h) or a methods approach to explore perceptions peak noise level in excess of 140 dB(lin). of a cross-section of the community to a spectrum of green spaces that could be The WA Department of Mines, Industry used for recreation, highlighting the likely Regulation and Safety (DMIRS) have a impacts on wellbeing and physical activity. guideline for the management of noise in WA mining operations. Outline: To understand variation in the perception of biodiversity; and to assess Despite this, noise measurements above whether people’s views on biodiversity are the exposure standard were recorded for linked with differential impacts on health 93% of underground production and well-being. employees, 73% of surface production employees, and 68% of ore treatment Methodology: Literature review, employees in mines between 1996 and questionnaires, focus groups, qualitative 2009. and/or quantitative data analysis. 22 The University of Western Australia
Outline: The aim of this study is to exposures. The cohort has been linked investigate noise levels in WA mines with administrative health records allowing between 1996 and 2016 to determine; 1) assessment of various health outcomes. the main contributing factors to elevated The overall aim of this study is to investigate level and 2) if there have been reductions in the short- and long-term health effects of noise over that 20 year period modern-day mining exposures, specifically silica and diesel. Methodology: Noise data has been collected by DMIRS since 1996. We will Outline: Are current mining emission regulations sufficient to preserve miners’ initially model the determinants of health? exceedance of the full-shift workplace noise exposure limit (LAeq,8h≥85 dBA) using This project offers potential students the logistic regression analyses. Models will opportunity to choose from a variety of include the type of mine, place of collection health outcomes (e.g. cancer, pulmonary, (eg surface or underground), and activities cardiovascular, renal, etc.). The scope conducted during collection. Trends over of a project will be tailored to suit the time will then be calculated candidate’s goals. Project Specific Requirements: Candidates will gain hands-on experience of applying core epidemiological concepts Statistical competency (ideally biostats II) and understand how epidemiological evidence is generated and used to inform policy and planning of occupational health Health effects of mining standards and guidelines. exposures? Methodology: Students will undertake Dr Peter Franklin a comprehensive literature review on their Background: Mining activities are chosen research question and develop a associated with exposure to harmful dusts research proposal, followed by quantitative and gases. Studies on mining cohorts have analyses of large linked datasets including advanced scientific knowledge on causal the cohort’s occupational and health relationships between these exposures histories. Analyses will include generation and chronic respiratory diseases (e.g. of disease frequencies, general population pneumoconiosis and lung cancer). This has comparisons, time trends, estimation of influenced regulatory changes over the past risks and dose-response relationships, etc. decades with improved respiratory health Scientific manuscripts for peer-reviewed outcomes. However, ongoing assessment is publication will be prepared. required to determine if these changes are Project Specific Requirements: sufficient in protecting miners’ health. Good literature reviewing skills and The WA miners’ cohort includes over statistical knowledge, e.g. Biostatistics II essential. 150,000 miners who worked and lived in WA between 1996 and 2012. Their occupational Project Length: 24 point MPH only histories have been decoded to assign quantitative exposure metrics for diesel and silica, two of the most common mining uwa.edu.au 23
Projects in Health and Labour Economics Building a robust Nursing 1. To examine the unemployment workforce and underemployment rate of nursing Dr Ian Li; Mr Rory Watts graduates, and the transition from unemployment to employment in the Background: The nursing workforce longer term is an important component of the health 2. To examine employment contract and workforce. However, research into the permanency for nursing graduates nursing workforce has been hampered by 3. To examine earnings of nursing a lack of rich, representative data. At the graduates in the short and long term, as same time, prior literature indicates that well as the distribution of earnings. Australia is likely to face a lack of nurses to 4. To examine whether employment meet demands for the future. More recently, outcomes differ for nursing graduates media reports suggest that newly qualified with an undergraduate qualification, as nurses are unable to secure appropriate opposed to a Masters entry-to-practice employment within Australia, and have type qualification had to pursue nursing careers overseas. Shortages in the nursing workforce and the Methodology: The analyses for this inability to secure appropriate employment, study will be primarily quantitative in has come to be known as the ‘nursing nature. The analyses will utilise a national workforce paradox’. survey of Australia graduates available from 2010-2017, which also includes longitudinal It is thus imperative that more research follow-up of the survey respondents. is conducted into the education-work transition of nurses, from universities into Project Specific Requirements: the workplace. Essential • Excellent report writing skills and Prior research looking at underemployment proficiency in English. of nursing graduates over 2008-2015 has • Biostatistics I or equivalent. tackled some of these issues, however, this research has only focussed on short-term Desirable outcomes post-university completion. The • Biostatistics II or equivalent . proposed program of study will examine • Competent in SPSS, Stata or equivalent. longer term outcomes. Outline: The aim of the study is to examine labour market outcomes for nursing graduates from Australian universities. A time-series of data is available, and hence trends in the following research objectives can also be explored. These outcomes include unemployment, earnings, underemployment, and contract type. 24 The University of Western Australia
How do unhealthy behaviours The undergraduate public health influence employment outcomes student: Where do they come Dr Ian Li from? Where will they go? Dr Ian Li; Mr Rory Watts Background: Unhealthy behaviours and lifestyle factors are areas of focus for health Background: Historically, the public policy. Thus far, most studies looking at health degree in Australia has been a these factors have focussed on their Master of Public Health (MPH). However, impacts on diseases and health outcomes. much of the public health education taught It has also been hypothesised that is now at an undergraduate level, either unhealthy lifestyles could also have through specific public health degrees, or further reaching impacts on employment through majors and units in other degrees outcomes. Consideration of the costs (e.g. health science). of adverse employment consequences would lend further policy weight in tackling Similarly, most research about public health unhealthy behaviours and lifestyles. students is focussed on the MPH, leaving an important research gap about the Outline: The aim of this study will be outcomes that undergraduate public health to look at several unhealthy behaviours students attain, and the value they add to derived from the literature and examine the workforce. the causal impact of these behaviours with several measure of employment outcomes Outline: The research project aims to answer the following questions about Methodology: This study will use undergraduates of public health: data from a nationally representative, 1. What are the employment rates in terms longitudinal dataset called the Household of underemployment, unemployment, part- Income and Labour Dynamics Australia time and full-time work, hours worked and (HILDA) study. The HILDA study commenced in 2001 and has an annual follow up, with contract type the 17th wave of data being made available 2. In which jobs and industries do public recently. Longitudinal analytical regression health graduates work and do they feel this techniques will be used for this study. is a good-fit? 3. If undergraduates go on to further study, Project Specific Requirements: what do they study? Essential 4. How have these changed over time? • Excellent report writing skills and proficiency in English. Methodology: The analyses for this • Biostatistics I or equivalent study will be primarily quantitative in nature. The analyses will utilise a national Desirable survey of Australia graduates available from • Biostatistics II or equivalent . 2007-2018, which also includes longitudinal • Competent in SPSS, Stata or equivalent. follow-up of the survey respondents. Linear and binary outcome regression techniques will be used in the analysis of the data. Project Specific Requirements: Essential • Excellent report writing skills and proficiency in English. uwa.edu.au 25
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