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PROCEEDINGS OF SPIE
SPIEDigitalLibrary.org/conference-proceedings-of-spie
Front Matter: Volume 7182
, "Front Matter: Volume 7182," Proc. SPIE 7182, Imaging, Manipulation, and
Analysis of Biomolecules, Cells, and Tissues VII, 718201 (16 March 2009);
doi: 10.1117/12.824923
Event: SPIE BiOS, 2009, San Jose, California, United States
Downloaded From: https://www.spiedigitallibrary.org/conference-proceedings-of-spie on 10 Apr 2021 Terms of Use: https://www.spiedigitallibrary.org/terms-of-usePROGRESS IN BIOMEDICAL OPTICS AND IMAGING
Vol. 10, No. 22
Imaging, Manipulation, and
Analysis of Biomolecules, Cells,
and Tissues VII
Daniel L. Farkas
Dan V. Nicolau
Robert C. Leif
Editors
26–28 January 2009
San Jose, California, United States
Sponsored and Published by
SPIE
Volume 7182
Proceedings of SPIE, 1605-7422, v. 7182
SPIE is an international society advancing an interdisciplinary approach to the science and application of light.
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-useThe papers included in this volume were part of the technical conference cited on the cover and
title page. Papers were selected and subject to review by the editors and conference program
committee. Some conference presentations may not be available for publication. The papers
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(SPIE, Bellingham, WA, 2009) Article CID Number.
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-useContents
ix Conference Committee
SESSION 1 TISSUE IMAGING
7182 02 In vivo optical analysis of pancreatic cancer tissue in living model mice using fluorescence
and Raman spectroscopic techniques [7182-01]
T. Suzuki, Y. Hattori, T. Katagiri, H. Mitsuoka, The Institute of Physical and Chemical
Research-RIKEN (Japan); K. Sato, Tohoku Univ. (Japan); T. Asakura, Tohoku Univ. (Japan)
and Miyagi Gakuin Women’s Univ. (Japan); T. Shimosegawa, Tohoku Univ. (Japan); H. Sato,
The Institute of Physical and Chemical Research-RIKEN (Japan)
7182 04 Label-free imaging of arterial tissues using photonic crystal fiber (PCF) based nonlinear
optical microscopic system [7182-03]
A. C. T. Ko, A. Ridsdale, A. F. Pegoraro, M. S. D. Smith, L. B. Mostaço-Guidolin, M. D. Hewko,
E. M. Kohlenberg, B. J. Schattka, National Research Council Canada (Canada); M. Shiomi,
Kobe Univ School of Medicine (Japan); A. Stolow, M. G. Sowa, National Research Council
Canada (Canada)
7182 05 Raman microspectroscopy of retinal pigment epithelium cells: real-time imaging the effects
of photooxidative stress [7182-04]
A. Saha, R. Arora, V. V. Yakovlev, Univ. of Wisconsin, Milwaukee (United States); M. L. Denton,
G. D. Noojin, Northrop Grumman Mission Systems (United States); R. J. Thomas, Air Force
Research Lab. (United States); J. M. Burke, Medical College of Wisconsin (United States)
7182 06 Spectral histology of breast tissue using mid-infrared spectroscopic imaging [7182-05]
F. N. Pounder, R. Bhargava, Univ. of Illinois at Urbana-Champaign (United States)
7182 07 Full pupil line-scanning confocal microscope for imaging weakly scattering tissues:
comparison to divided pupil [7182-06]
D. S. Gareau, S. Abeytunge, M. Rajadhyaksha, Memorial Sloan-Kettering Cancer Ctr.
(United States)
SESSION 2 CELL IMAGING I
7182 08 Fluorescence intensity, lifetime, and anisotropy screening of living cells based on total
internal reflection techniques (Invited Paper) [7182-07]
T. Bruns, Hochschule Aalen (Germany); B. Angres, H. Steuer, Univ. Tübingen (Germany);
W. S. L. Strauss, Univ. Ulm (Germany); H. Schneckenburger, Hochschule Aalen (Germany)
and Univ. Ulm (Germany)
iii
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-use7182 09 Imaging living hair cells within the cochlear epithelium of mice using two-photon
microscopy [7182-08]
T. Yuan, Baylor College of Medicine (United States); S. S. Gao, Rice Univ. (United States);
P. Saggau, Rice Univ. (United States) and Baylor College of Medicine (United States);
J. S. Oghalai, Baylor College of Medicine (United States) and Rice Univ. (United States)
7182 0A Cellular imagery with total internal reflection holographic microscopy [7182-09]
W. M. Ash III, M. K. Kim, Univ. of South Florida (United States)
SESSION 3 CELL IMAGING II
7182 0D Spectral imaging of microvascular function in a renal cell carcinoma after treatment with a
vascular disrupting agent [7182-12]
M. Wankhede, C. deDeugd, D. W. Siemann, B. S. Sorg, Univ. of Florida (United States)
7182 0E Structural characterization of colored human iridal melanosomes by photo emission
electron microscopy [7182-13]
D. N. Peles, L. Hong, J. D. Simon, Duke Univ. (United States); D.-N. Hu, The New York Eye and
Ear Infirmary, New York Medical College (United States)
7182 0F Direct Raman imaging spectroscopy of lung cancer cells and apoptotic cells [7182-14]
Y. Oshima, Aoyama Gakuin Univ. (Japan) and The Institute of Physical and Chemical
Research-RIKEN (Japan); C. Furihata, Aoyama Gakuin Univ. (Japan); H. Sato, The Institute of
Physical and Chemical Research-RIKEN (Japan)
7182 0G Functional imaging of a single cell: far-field infrared super-resolution microscopy using
autofluorescence detection [7182-15]
T. Ohmori, National Defense Medical College (Japan); K. Inoue, M. Sakai, M. Fujii, Tokyo
Institute of Technology (Japan); M. Ishihara, M. Kikuchi, National Defense Medical College
(Japan)
SESSION 4 BIOMOLECULAR IMAGING
7182 0I Dynamic molecular imaging of living cells by using Raman scattering [7182-17]
K. Fujita, K. Hamada, N. I. Smith, Y. Inouye, Osaka Univ. (Japan); S. Kawata, Osaka Univ.
(Japan) and The Institute of Physical and Chemical Research-RIKEN (Japan)
7182 0J Serum protein profile study of clinical samples using high performance liquid
chromatography-laser induced fluorescence: case of cervical and oral cancers [7182-18]
G. Karemore, Univ. of Copenhagen (Denmark) and Nordic Bioscience (Denmark);
Sujatha, L. Rai, K. M. Pai, V. B. Kartha, Santhosh C, Manipal Univ. (India)
7182 0K Physical mechanism of delayed luminescence from human serum [7182-19]
H. Bai, P. Chen, L. Lin, S. Chang, G. Tang, G. Mu, Nankai Univ. (China)
7182 0L Evaluation of optimal DNA staining for triggering by scanning fluorescence microscopy
(SFM) [7182-20]
A. Mittag, M. Marecka, A. Pierzchalski, Univ. Leipzig (Germany); W. Malkusch, Carl Zeiss
Imaging Solutions GmbH (Germany); J. Bocsi, A. Tárnok, Univ. Leipzig (Germany)
iv
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-use7182 0M High-performance dispersive Raman and absorption spectroscopy as tools for drug
identification [7182-21]
O. Pawluczyk, S. Andrey, P. Nogas, A. Roy, R. Pawluczyk, P&P Optica Inc. (Canada)
SESSION 5 MICROANALYSIS AND MICROARRAYS I
7182 0P Label-free optical detection of small-molecule compound microarrays immobilized on
solid support using macromolecular scaffolds and subsequent protein binding reactions
[7182-24]
Y. S. Sun, J. P. Landry, Y. Y. Fei, X. D. Zhu, J. T. Luo, X. B. Wang, K. S. Lam, Univ. of California,
Davis (United States)
7182 0Q Label-free screening small-molecule compound libraries for protein-ligands using a
high-throughput optical scanning microscope [7182-25]
Y. Y. Fei, J. P. Landry, Y. S. Sun, X. D. Zhu, X. B. Wang, J. T. Luo, C. Y. Wu, K. S. Lam, Univ. of
California, Davis (United States)
SESSION 6 MICROANALYSIS AND MICROARRAYS II
7182 0V Hollow fiber: a biophotonic implant for live cells [7182-30]
O. F. Silvestre, Cardiff Univ. (United Kingdom); M. D. Holton, H. D. Summers, Swansea Univ.
(United Kingdom); P. J. Smith, R. J. Errington, Cardiff Univ. (United Kingdom)
SESSION 7 OPTICAL MANIPULATION AND PROBING
7182 0Y Probing the mechanical properties of Drosophila embryo ephitelial cells in vivo by laser
nanodissection [7182-33]
M. Rauzi, Institut de Biologie du Développement de Marseille Luminy, CNRS (France) and
Institut Fresnel, CNRS, Univ. Aix Marseille (France); E. P. Mottay, Amplitude Systemes (France);
T. Lecuit, Institut de Biologie du Développement de Marseille Luminy, CNRS (France);
P.-F. Lenne, Institut de Biologie du Développement de Marseille Luminy, CNRS (France) and
Institut Fresnel, CNRS, Univ. Aix Marseille (France)
7182 0Z Photoablative dilution with pre-enrichment for the clonal isolation of rare cancer cells
[7182-35]
M. D. Zordan, J. F. Leary, Purdue Univ. (United States)
7182 10 Quantitative phase evaluation of dynamic changes on the cell membrane during laser
microsurgery [7182-36]
L. Yu, S. Mohanty, G. Liu, S. Genc, Univ. of California, Irvine (United States); M. K. Kim, Univ. of
South Florida (United States); Z. Chen, M. W. Berns, Univ. of California, Irvine (United States)
7182 11 Cell palpation system for local mechanical properties of a cell with an optically
manipulated particle [7182-37]
H. Miyoshi, T. Sugiura, K. Minato, Nara Institute of Science and Technology (Japan)
7182 13 Dynamic behaviour of fungi in microfluidics: a comparative study [7182-83]
M. Held, M. Binz, C. Edwards, D. V. Nicolau, The Univ. of Liverpool (United Kingdom)
v
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-use7182 14 Ventricular defibrillation combining DC electrical field and electrical pacing: an optical
mapping study [7182-39]
S. S. Musunuri, L. Tang, B. Joung, E. J. Berbari, S.-F. Lin, Indiana Univ. School of Medicine
(United States)
SESSION 8 NEW IMAGING TECHNIQUES
7182 17 Effect of time gating and polarization discrimination of propagating light in turbid media
during angular domain imaging (ADI) [7182-42]
F. Vasefi, Simon Fraser Univ. (Canada) and Lawson Health Research Institute (Canada);
E. Ng, Lawson Health Research Institute (Canada) and Univ. of Western Ontario (Canada);
B. Kaminska, G. H. Chapman, Simon Fraser Univ. (Canada); J. J. L. Carson, Lawson Health
Research Institute (Canada) and Univ. of Western Ontario (Canada)
7182 18 Solid state photomultipliers for biomedical imaging applications [7182-43]
G.-C. Wang, J. Gordon, General Electric Global Research (United States)
7182 19 High-speed fluorescence lifetime measurement for investigation of dynamic phenomena
[7182-44]
Y. Won, S. Moon, D. Lee, D. Y. Kim, Gwangju Institute of Science and Technology (Korea,
Republic of)
SESSION 9 IMAGE ANALYSIS
7182 1A Red blood cell structure and dynamics explored with digital holographic microscopy
[7182-45]
P. Marquet, Univ. of Lausanne (Switzerland) and Ecole Polytechnique Fédérale de Lausanne
(Switzerland); B. Rappaz, Ecole Polytechnique Fédérale de Lausanne (Switzerland);
A. Barbul, R. Korenstein, Tel Aviv Univ. (Israel); C. Depeursinge, Ecole Polytechnique Fédérale
de Lausanne (Switzerland); P. Magistretti, Univ. of Lausanne (Switzerland) and Ecole
Polytechnique Fédérale de Lausanne (Switzerland)
7182 1C Image contrast enhancement during time-angular domain imaging through turbid media
by estimation of background scattered light [7182-47]
E. Ng, Lawson Health Research Institute (Canada) and The Univ. of Western Ontario
(Canada); F. Vasefi, Lawson Health Research Institute (Canada) and Simon Fraser Univ.
(Canada); B. Kaminska, G. H. Chapman, Simon Fraser Univ. (Canada); J. J. L. Carson,
Lawson Health Research Institute (Canada) and Univ. of Western Ontario (Canada)
7182 1D Dynamic reconfigurable spectral imaging microscopy [7182-48]
B. Chen, Univ. of Miami (United States); J. J. Yang, New Span Opto-Technology Inc. (United
States); M. R. Wang, Univ. of Miami (United States)
7182 1F Hyperspectral microscopy imaging to analyze pathology samples with multicolors reduces
time and cost [7182-50]
M. L. Huebschman, Univ. of Texas Southwestern Medical Ctr. (United States);
K. P. Rosenblatt, Univ. of Texas Medical Branch (United States); H. R. Garner, Univ. of Texas
Southwestern Medical Ctr. (United States)
vi
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-use7182 1G Microscopy with spatial filtering for sorting particles and monitoring subcellular morphology
[7182-51]
J.-Y. Zheng, Z. Qian, R. M. Pasternack, N. N. Boustany, Rutgers Univ. (United States)
7182 1H Molecular analysis of arterial remodeling: a novel application of infrared imaging [7182-52]
B. C. Herman, R. Kundi, Weill Cornell Medical College (United States); D. Yamanouchi,
K. C. Kent, Univ. of Wisconsin (United States); B. Liu, Weill Cornell Medical College (United
States) and Univ. of Wisconsin (United States); N. Pleshko, Exponent (United States)
SESSION 10 OPTICAL QUANTIFICATION I
7182 1K Measurements and analysis in imaging for biomedical applications [7182-55]
T. L. Hoeller, DQR Testing Services (United States)
SESSION 11 OPTICAL QUANTIFICATION II
7182 1L Determination of glucose concentration using Fourier domain optical coherence tomogram
[7182-56]
Y. H. El-Sharkawy, Egyptian Armed Forces (Egypt)
7182 1M A two-stage morphological classifier of foci occurring in cell transformation assays [7182-57]
G. F. Crosta, C. Urani, L. Bussinelli, Univ. degli Studi di Milano-Bicocca (Italy)
7182 1O Dynamic fluorescence imaging for multiparametric measurement of tumor vasculature
[7182-61]
M. Choi, T. Chung, K. Choi, C. Choi, Korea Advanced Institute of Science and Technology
(Korea, Republic of)
7182 1P The measurement of red blood cell volume induced by Ca2+ based on full field quantitative
phase microscopy [7182-62]
S. Lee, J. Y. Lee, W. Yang, D. Y. Kim, Gwangju Institute of Science and Technology (Korea,
Republic of)
SESSION 12 CYTOMICS
7182 1Q A container for the advanced cytometry standard (ACS) [7182-63]
R. C. Leif, Newport Instruments (United States); J. Spidlen, R. R. Brinkman, BC Cancer
Research Ctr. (Canada)
7182 1R Evaluation of slide based cytometry (SBC) for concentration measurements of fluorescent
dyes in solution [7182-64]
A. Pierzchalski, M. Marecka, Univ. Leipzig (Germany); H.-W. Müller, Sensovation AG
(Germany); J. Bocsi, A. Tárnok, Univ. Leipzig (Germany)
7182 1S Triggering of leukocytes by phase contrast in imaging cytometry with scanning
fluorescence microscope (SFM) [7182-65]
J. Bocsi, A. Pierzchalski, M. Marecka, Univ. Leipzig (Germany); W. Malkusch, Carl Zeiss
Imaging Solutions GmbH (Germany); A. Tárnok, Univ. Leipzig (Germany)
7182 1T Laser rastering flow cytometry: fast cell counting and identification [7182-81]
vii
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-useG. Vacca, M. R. Junnarkar, N. R. Goldblatt, M. W. Yee, Abbott Hematology (United States);
B. M. Van Slyke, T. C. Briese, Plexus Technology Group (United States)
POSTER SESSION
7182 1U Angiogram, fundus, and oxygen saturation optic nerve head image fusion [7182-60]
H. Cao, B. Khoobehi, Louisiana State Univ. (United States)
7182 1V High-resolution imaging of biological cell with fiber-based composite interferometer
[7182-66]
H.-I. Hsu, C.-W. Chang, Chung Yuan Christian Univ. (Taiwan); M. T.-K. Hou, National United
Univ. (Taiwan); I.-J. Hsu, Chung Yuan Christian Univ. (Taiwan)
7182 1W Atmospheric pressure femtosecond laser imaging mass spectrometry [7182-68]
Y. Coello, T. C. Gunaratne, M. Dantus, Michigan State Univ. (United States)
7182 1X Optical property of red blood cell with a phase microscopy interferometer [7182-69]
J. Y. Lee, S. Lee, W. Yang, D. Y. Kim, Gwangju Institute of Science and Technology (Korea,
Republic of)
7182 1Y Polarization microscope by single polarization modulation method: novel instrument for
visualizing cytoskeleton [7182-70]
I. H. Shin, S.-M. Shin, N. Ahn, D. Y. Kim, Gwangju Institute of Science and Technology (Korea,
Republic of)
Author Index
viii
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-useConference Committee
Symposium Chairs
James G. Fujimoto, Massachusetts Institute of Technology (United
States)
R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts
General Hospital (United States) and Harvard School of Medicine
(United States)
Program Track Chairs
Ammasi Periasamy, University of Virginia (United States)
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
Conference Chairs
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
Dan V. Nicolau, The University of Liverpool (United Kingdom)
Robert C. Leif, Newport Instruments (United States)
Cochairs
J. Paul Robinson, Purdue University (United States)
Attila Tarnok, Universität Leipzig (Germany)
Ramesh Raghavachari, U.S. Food and Drug Administration (United
States)
James F. Leary, Purdue University (United States)
Program Committee
Christopher H. Contag, Stanford University School of Medicine (United
States)
Paul Dan A. Cristea, Universitatea Politehnica Bucharest (Romania)
Alberto Diaspro, Università degli Studi di Genova (Italy)
Erik G. Fällman, Umeå Universitet (Sweden)
Jesper Glückstad, Danmarks Tekniske Universitet (Denmark)
Ewa M. Goldys, Macquarie University (Australia)
Charles P. Lin, Massachusetts General Hospital (United States)
Andreas G. Nowatzyk, Cedars-Sinai Medical Center (United States)
Markus Sauer, Universität Bielefeld (Germany)
ix
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Terms of Use: https://www.spiedigitallibrary.org/terms-of-useSession Chairs
1 Tissue Imaging
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
2 Cell Imaging I
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
3 Cell Imaging II
James F. Leary, Purdue University (United States)
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
4 Biomolecular Imaging
Attila Tarnok, Universität Leipzig (Germany)
5 Microanalysis and Microarrays I
Robert C. Leif, Newport Instruments (United States)
6 Microanalysis and Microarrays II
James F. Leary, Purdue University (United States)
7 Optical Manipulation and Probing
Daniel L. Farkas, Cedars-Sinai Medical Center (United States)
8 New Imaging Techniques
Dan V. Nicolau, The University of Liverpool (United Kingdom)
9 Image Analysis
Dan V. Nicolau, The University of Liverpool (United Kingdom)
10 Optical Quantification I
Robert C. Leif, Newport Instruments (United States)
11 Optical Quantification II
Robert C. Leif, Newport Instruments (United States)
12 Cytomics
Attila Tarnok, Universität Leipzig (Germany)
x
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