Pneumonia & Diarrhea Progress Report 2015 - Johns Hopkins Bloomberg School of Public ...
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Executive Summary 4 Global Burden of Pneumonia and Diarrhea in Children 5 Evaluating Progress in the 15 Highest Burden Countries 6 Key Progress Updates 7 Introduction 8 Contents Pneumonia and Diarrhea – Major Threats to Child Health and Survival 8 Measuring and Evaluating Country Progress 8 GAPPD Intervention Scoring 10 Key Findings: GAPPD Package Coverage 11 Key Findings: Prevention through Vaccination 17 DTP3 Coverage 18 Measles Coverage 18 Hib Vaccine Coverage 18 PCV Coverage 19 Rotavirus Vaccine Coverage 19 Striving to Achieve and Maintain High, Equitable Vaccine Coverage 20 Country Highlights 21 India 22 Indonesia 23 Nigeria 25 Key Findings: Protection 27 Exclusive Breastfeeding 28 Key Findings: Treatment 29 Pneumonia Treatment: Care by Appropriate Health Care Provider and Antibiotics 30 Diarrhea Treatment: Oral Rehydration Salts (ORS) and Zinc 31 Sustainable Progress in the Post-2015 Era 32 Vaccine Financing 34 Impact of Changing Levels of Gavi Support 35 Immunization Systems, Supply Chains, and Decision Making Capacity 36 Capacity to Scale Up Interventions and Sustain Progress 38
Acknowledgements This 2015 edition of the Pneumonia and Diarrhea Progress Report is the sixth annual progress report prepared and published by the International Vaccine Access Center (IVAC) www.jhsph.edu/ivac at the Johns Hopkins Bloomberg School of Public Health for World Pneumonia Day. 7th Annual World Pneumonia Day 2015 (November 12, 2015) Report Team Lead Author Thuy-Linh Nguyen Contributors (IVAC) Katherine L. O’Brien Lois Privor-Dumm Maria Knoll Elizabeth Chan Molly Sauer Margaret Miller Chizoba Wonodi Chisom Obi Expert Reviewers Mathuram Santosham Robert Black Li Liu Design and Layout John Welker, Pixels+Points Photos Adrian Brooks Oscar Seykens Suggested Citation International Vaccine Access Center (IVAC), Johns Hopkins Bloomberg School of Public Health. (2015). Pneumonia and Diarrhea Progress Report 2015: Sustainable Progress in the Post-2015 Era. Retrieved from www.jhsph. edu/research/centers-and-institutes/ivac/ resources/IVAC-2015-Pneumonia-Diarrhea- Progress-Report.pdf
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children Executive Summary IVAC at Johns Hopkins University
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children Executive Summary Global Burden of Pneumonia and Diarrhea in Children Every minute, six children die from pneumonia or diarrhea. Together, these diseases claimed the lives of nearly 1.5 million children under the age of five in 2015. This year, 2015, marks the end of the age of five in a single year. The lives of Millennium Development Goals (MDGs), six children are lost with each passing 5.9m and an opportunity to reflect on the minute. Although the number of child drastic improvements in child health deaths in 2015 decreased compared and survival that have been achieved to 2013 (6.4 million), the overall over the past decades along with the contribution of pneumonia and diarrhea need for sustained improvement. In to those deaths has remained rather 9% 2015, the mortality rate in children under steady (15-16% for pneumonia and 9% deaths the age of five years is less than half for diarrhea) over those two years.1 (43 deaths per 1,000 live births) of what diarrhea it was in 1990 (91 deaths per 1,000 live In addition, pneumonia and diarrhea 16% births). However, this still falls short of mortality in young children continues the MDG4 target of reducing under-five to be disproportionately concentrated mortality by two-thirds between 1990 in a few countries, year after year. pneumonia and 2015. This reality serves as a stark Seventy-two percent of the global reminder of the work that remains to be burden of pneumonia and diarrhea child done and the continued investments deaths occur in just 15 countries, even that are required to accelerate the pace though they are home to only 55% of the of progress in the post-2015 era. world’s under-five population. Of these 5.9 million In 2015, a projected 5.9 million children deaths, pneumonia around the world will die before reaching was responsible for their fifth birthday.1 Of these 5.9 million 16% and diarrhea was deaths, pneumonia was responsible responsible for 9%, for 16% and diarrhea was responsible for 9%, making them two of the leading making them two of killers of children worldwide. Together, the leading killers of these diseases claimed the lives of children worldwide. nearly 1.5 million children under the IVAC at Johns Hopkins University 5
Executive Summary | Evaluating Global Burden Progress of Pneumonia in the 15 and Highest Diarrhea Burden in Children Countries Evaluating Progress in the 15 Highest Burden Countries This 2015 Pneumonia and Diarrhea Progress Report evaluates the progress of the 15 countries with the greatest burden of under-five pneumonia and diarrhea deaths in implementing high-impact interventions outlined in the Global Action Plan for the Prevention and Control of Pneumonia and Diarrhea (GAPPD)3, where data are available, and evaluates the need to accelerate the implementation of select interventions Collectively, these ten interventions and assure sustainability of that progress. are evaluated and summarized into an overall GAPPD score, developed by the International Vaccine Access Center (IVAC) at the Johns Hopkins Bloomberg School of Public Health. These GAPPD scores are used to assess and compare The coverage targets for interventions included progress over time in the highest-burden in this report are: countries with the greatest number of pneumonia and diarrhea deaths in 90% for vaccinations children under the age of five years. Pertussis vaccine GAPPD scores are a calculated average Measles vaccine of countries’ coverage levels for the ten GAPPD indicators, using the most Haemophilus influenzae type b (Hib) vaccine recent data available. Pneumococcal conjugate vaccine Rotavirus vaccine 90% for pneumonia and diarrhea treatments Treatment of children with suspected pneumonia by a health care provider Antibiotic use in children with suspected pneumonia Oral rehydration salts (ORS) for children with diarrhea Zinc supplements for children with diarrhea 50% for exclusive breastfeeding Exclusive breastfeeding for the first 6 months of life Pneumonia & Diarrhea Progress Report 2015 6
Executive Summary | Key Progress Updates Key Progress Updates Between 2014 and 2015, 7 of the 15 countries with the greatest burden of child pneumonia and diarrhea deaths showed improvements in their GAPPD scores. However, gains were minimal in large countries, such as India and Nigeria. Between 2014 and 2015, the 15 countries with the greatest number of pneumonia and diarrhea child deaths have remained largely unchanged, with two exceptions. Uganda and Kenya dropped from the list in 2015, and were replaced by Somalia and Tanzania. For the remaining countries on the list in both 2014 and 2015, mixed progress was observed. GAPPD scores improved modestly for some countries (Democratic Republic of the Congo, Angola, Ethiopia, Afghanistan, and Sudan); remained unchanged for Indonesia, Niger, and China; and decreased for others (Pakistan, Chad, and Bangladesh). Furthermore, India and Nigeria, the two countries that consistently have the greatest number of pneumonia and diarrhea deaths under-five, improved their GAPPD scores by only two percentage points. GAPPD Score Change from 2014-2015 DRC Angola Indonesia Pakistan Ethiopia Niger Chad Afghanistan China Bangladesh Sudan Reflecting on the rate of progress over the past few years, it has become increasingly evident that without significant gains in countries with large birth cohorts, such as India, Nigeria, China, and Indonesia, reduction in global pneumonia and diarrhea mortality in children will continue to stall, as has been the case in recent years. The rate of uptake and scale-up of child mortality relative to its 1990 rate Low GAPPD scores in this report may be evidence-based interventions that and thus met the MDG4 target, they still due to a number of factors, including but protect against, prevent, and treat bear a significant burden of pneumonia not limited to a lack of implementation pneumonia and diarrhea have not kept and diarrhea child deaths worldwide. of GAPPD interventions (e.g., no up with the pace required for countries Particularly in large countries or introduction of the vaccines that to meet the MDG4 target of reducing countries that once had extremely can impact pneumonia and diarrhea under-five mortality by two-thirds by high child mortality rates, the absolute mortality), slow rollout of vaccines that 2015. In fact, more than half of the number of child deaths (all-cause or have been introduced (which is often countries evaluated in this report have pneumonia and diarrhea only) in 2015 the case for phased introductions in missed the target.1 Although Ethiopia, can still be high relative to those of large countries), and challenges in Indonesia, Niger, China, Bangladesh, other countries, despite a large relative changing health behaviors, specifically and Tanzania successfully achieved reduction in their mortality rates with regard to adopting protective and at least a two-thirds reduction in their over time. treatment measures. IVAC at Johns Hopkins University 7
Introduction | Introduction Pneumonia and Diarrhea – though these countries only account pneumonia and diarrhea interventions for 55% of the world’s under-five as recommended by the World Health Major Threats to Child Health Organization (WHO) and the United population.5 Of these 15 countries with and Survival the greatest number of pneumonia Nations Children’s Fund (UNICEF) in the and diarrhea child deaths, 6 (Angola, Global Action Plan for the Prevention Over the past 25 years, the rate of Chad, Somalia, Nigeria, Democratic and Control of Pneumonia and mortality in children under the age of Republic of Congo (DRC), and Niger) Diarrhea (GAPPD). Additionally, actual five years has been cut by more than are also among the 10 countries with coverage levels for each intervention half worldwide (from 91 deaths per 1,000 the highest under-five mortality rates are compared to coverage targets set live births in 1990 to 43 deaths per 1,000 and 9 (India, Nigeria, Pakistan, DRC, forth in GAPPD to assess how close or live births in 2015).1 Still, reaching a fifth Angola, Chad, Afghanistan, Sudan, and far countries are from meeting global birthday is a life milestone that many Somalia) have missed the MDG4 target standards for pneumonia and diarrhea children will never reach, especially in for the reduction of child mortality.1 prevention and treatment. the poorest areas of the world. In 2015, The remainder (Ethiopia, Indonesia, the number of childhood deaths is Niger, China, Bangladesh, and Tanzania) expected to reach 5.9 million. Despite have achieved their MDG4 targets, but significant gains in overall child health remain in the top 15 countries due to Protect. achieved across the globe, the world the high absolute burden of pneumonia has still fallen short of reaching its goal and diarrhea, and therefore should Prevent. of reducing 1990 under-five mortality continue to focus on further reductions by two-thirds by 2015. Pneumonia and of pneumonia and diarrhea mortality, Treat. diarrhea’s contribution to under-five particularly amongst their most child deaths, in particular, have remained vulnerable populations. stubbornly high.1,2 In 2015, these two diseases together were responsible Measuring and Evaluating GAPPD provides an integrated strategy for one in four deaths that occurred in Country Progress for ending preventable pneumonia children under five years of age.4 The majority of the total burden of pneumonia and diarrhea deaths through the use This report evaluates the progress of the and diarrhea child deaths globally (1.5 of proven measures that protect child 15 countries with the greatest number million) is also disproportionately borne health, prevent children from becoming of deaths from pneumonia and diarrhea by 15 countries. Of the children who lost ill with pneumonia and diarrhea, and in children under the age of five years, their lives to pneumonia and diarrhea treat affected children. using the most up-to-date information before the age of five, 72% are from on countries’ use of high-impact these 15 high-burden countries,4 even Pneumonia & Diarrhea Progress Report 2015 8
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children GAPPD sets forth the following coverage for each coverage of the following 90% vaccines: pertussis, targets for its measles, Haemophilus recommended influenzae type b (Hib), pneumococcal interventions, conjugate, and rotavirus vaccines which countries should strive treatment coverage to achieve: for children 90% with suspected pneumonia, including care by an appropriate health care provider and antibiotics treatment coverage for children with 90% diarrhea, including treatment with oral rehydration salts (ORS) and zinc supplements rate of exclusive 50% breastfeeding for the child’s first six months of life IVAC at Johns Hopkins University 9
Introduction | GAPPD Intervention Scoring GAPPD Intervention Scoring GAPPD scores are composite scores dose of measles-containing vaccine countries in terms of providing children that are calculated from countries’ (MCV1), third dose of Hib vaccine (Hib3), coverage of high-impact interventions most recent coverage, expressed as a third dose of pneumococcal conjugate that protect against, prevent, and treat proportion, for key GAPPD interventions, vaccine (PCV3), and the last dose pneumonia and diarrhea, integrating for which data are available. There of rotavirus vaccine (RV); exclusive strategies that impact either pneumonia are ten indicators that factor into the breastfeeding for the first six months or diarrhea, as well as those that impact GAPPD score, which represents a of a child’s life; care by an appropriate both. For a closer look at countries’ summary of coverage and is calculated health care provider and antibiotic progress with respect to pneumonia and as the average coverage across treatment for children with suspected diarrhea interventions separately, GAPPD- interventions based on available data. pneumonia; and treatment with ORS Pneumonia and GAPPD-Diarrhea scores, These intervention measures include and zinc for children with diarrhea. which respectively take into account only coverage rates for the third dose of The overall GAPPD scores provide pneumonia-specific and diarrhea-specific pertussis (as measured by DTP3), first an overview of the progress made in interventions, are also reported. The coverage indicators that are included in each score are outlined below: Pneumonia Treatments Diarrhea Treatments RV Exclusive Score DTP3 MCV1 Hib3 PCV3 (last Care by an breastfeeding dose) appropriate Zinc in first 6 Antibiotics ORS supplements health care months provider Overall GAPPD score GAPPD- Pneumonia score GAPPD- Diarrhea score GAPPD scores reflect countries’ progress on ten key GAPPD interventions for which coverage data are publicly available; they are not intended to represent the full portfolio of interventions that are effective in reducing pneumonia and diarrhea morbidity and mortality in children. Therefore, non-inclusion of interventions in the GAPPD score calculations does not imply their lack of importance in the prevention and treatment of childhood pneumonia and diarrhea. Considerations for Interpreting GAPPD Scores: Recent data (within the last 10 years) are not available for certain GAPPD indicators and are thus excluded from the calculation of GAPPD scores. As a result, countries with several missing values may have scores that either overestimate or underestimate the true progress being made in the country. Additionally, progress may appear stalled in countries where coverage estimates for GAPPD indicators are not updated annually, even if the country has made improvements in recent years. This underscores the importance of ongoing monitoring and availability of high quality data on key GAPPD interventions, which will not only enhance the quality of programs delivering these interventions, but also allow an accurate and up-to-date assessment of countries’ progress. In addition, immunization coverage rates calculated in the GAPPD scores are from the WHO/UNICEF Estimates of National Immunization Coverage (WUENIC), which are updated on an annual basis for the most recent year, as well as for all previous years, taking into account any new survey data that were made available since the last WUENIC data were released. Any changes in estimated coverage rates of previous years do not imply increases or decreases in actual coverage in that given year; rather, they reflect an adjustment of coverage estimates based on the latest available survey data. Therefore, changes between the 2013 vaccine coverage rates reported in the 2014 Pneumonia & Diarrhea Progress Report and the 2014 rates reported in this year’s Progress Report can be due to WHO/UNICEF’s adjustments of 2013 coverage rates in its latest (2015) release or a true increase or decrease in coverage levels from 2013 to 2014. In this 2015 Progress Report, when assessing trends across years, coverage rates from the latest WUENIC data are used, not the 2013 WUENIC coverage rates issued in 2014 and reported in the 2014 Progress Report. IVAC at Johns Hopkins University 10
Key Findings | GAPPD Package Coverage Key Findings GAPPD Package Coverage Overall GAPPD scores in 2015 varied widely from a low of 20% (Somalia) to a high of 72% (Tanzania), with all 15 focus countries falling below the 86% target for the overall GAPPD score. Large countries, such as India, Nigeria, Indonesia, and China had little to no improvement in their GAPPD scores since last year. These large countries with low coverage of lifesaving interventions that protect against, prevent, and treat pneumonia and diarrhea represent critical opportunities to bend the curve on child mortality. In 2015, the 15 countries that contributed (10) Niger, (11) China, (12) Sudan, (13) (Uganda, Kenya, Somalia, and Tanzania), most to the global burden of child Bangladesh, (14) Somalia, and (15) the combined burden of child mortality pneumonia and diarrhea deaths were United Republic of Tanzania (listed in from pneumonia and diarrhea did largely the same as those in 2014, with decreasing order of pneumonia and decrease between 2013 and 2015.4 two exceptions. Between 2014 and diarrhea child deaths).6 This shuffling 2015, Uganda and Kenya dropped from of countries on and off the list of the This year, overall GAPPD scores varied the list of the 15 countries with the top 15 highest burden countries is due widely from a low of 20% (Somalia) to greatest number of under-five deaths to several factors, including reductions a high of 72% (Tanzania), the highest from pneumonia and diarrhea, and were in the total number of child pneumonia GAPPD score reached by any of the replaced by Somalia and Tanzania. and diarrhea deaths and an adjustment 15 highest-burden countries since These 15 highest burden countries of 2013 pneumonia and diarrhea burden we began evaluating pneumonia and now consist of (1) India, (2) Nigeria, (3) estimates in the latest update of the diarrhea interventions together in 2013 Pakistan, (4) DRC, (5) Angola, (6) Ethiopia, global burden of disease estimates (See Fig. 1 and 2 and Table 1). The (7) Indonesia, (8) Chad, (9) Afghanistan, released in 2015.4 In all 4 cases median score among the 15 countries was 46%. This represents a slight Figure 1: Overall GAPPD scores for the 15 countries with the greatest absolute improvement from 2014 scores, which number of pneumonia and diarrhea deaths in children under 5 years of age, 2015 ranged from 23% (Chad) to 63% (Sudan), and with a median score of 44%.6 However, only 4 of the 15 countries had overall GAPPD scores of at least 50% in 2015 (Angola, Sudan, Bangladesh, and Overall GAPPD Scores, 2015 Tanzania), and all 15 fell short of the 20-35 86% target for the overall GAPPD score, 36-50 which would be achieved if a country 51-60 met the minimum coverage targets for 61-72 each of the ten GAPPD interventions evaluated in this report. Pneumonia & Diarrhea Progress Report 2015 11
Table 1: Current levels of coverage for pneumonia and diarrhea interventions in the 15 countries with the most absolute child pneumonia and diarrhea deaths % of Children Under 5 % of Children Under 5 Global rank Pneumonia Vaccine Coverage (%) with Suspected Pneumonia with Diarrhea order of total & Diarrhea % Exclusive 2015 2015 2015 Overall pneumonia Deaths in Breastfeeding GAPPD- GAPPD- GAPPD and diarrhea Country Children in first 6 Pneumonia Diarrhea Hib3 Taken to an Intervention deaths in Under 5 PCV3 months7 Intervention Intervention Pertussis 20142 appropriate Receiving Receiving Receiving zinc Score children Years Measles 20142& Rota 20142 (2005-2014) Score Score (DTP3) & Vaccine health care Antibiotics3 ORS 4 supplements5,6 under 5 20151 20142 Vaccine Use & Vaccine Use Status 20142 Use provider 3 (2005-2014) (2005-2014) (2005-2014) Status Status (2005-2014) 1 India 297,114 83 83 20 0 0 69 12.5 26 0.3 46 34 45 31 No decision Non-Gavi planning intro 0 0 2 Nigeria 210,557 66 51 66 (Dec 2014) Gavi plan to apply 34.5 34.9 34 2.3 17 31 39 21 3 Pakistan 103,760 73 63 73 68 0 64.4 41.5 38 1.5 38 46 60 28 Gavi plan to apply Democratic 0 4 Republic of 78,422 80 77 80 61 No decision 41.6 39.6 39 2.4 48 47 61 33 the Congo 5 Angola 54,548 80 85 80 61 18 - - - - - 65 77 52 6 Ethiopia 46,888 77 70 77 76 63 27 6.8 26 0.0 52 48 55 42 0 0 7 Indonesia 33,737 78 77 21 Non-Gavi Non-Gavi planning intro 75.3 38.9 39 1.1 42 37 47 32 planning intro 0 0 8 Chad 30,641 46 54 46 No decision No decision 26.1 31.4 13 0.2 3 22 30 14 0 9 Afghanistan 30,419 75 66 75 40 Gavi plan to apply 60.5 63.9 53 5.3 - 49 63 31 10 Niger 28,164 68 72 68 13 19 53.1 10.7 44 10.3 23 38 44 34 Private 0 0 11 China 27,114 99 99 Market No decision No decision - - - - 28 45 56 42 Coverage 12 Sudan 24,903 94 86 94 97 86 48.3 59 22 - 41 70 74 59 0 0 13 Bangladesh 24,571 95 89 95 Introduced Gavi plan to apply 42 34.2 77 11.8 60 50 59 48 Mar 2015 0 0 14 Somalia* 23,426 42 46 42 No decision No decision 13 32 13 0.9 9 20 26 14 Tanzania, 15 United 22,394 97 99 97 93 97 70.6 - 44 4.7 50 72 84 59 Republic of* *Not profiled in the 2014 Pneumonia & Diarrhea Progress Report; was not among the top 15 countries with the highest number of child pneumonia and diarrhea deaths in the previous year. Sources: 1 Liu, L., Oza, S., Hogan, D., Chu, Y., Perin, J., Zhu, J., Lawn, J., Cousens, S., Mathers, C., Black, R. E. (2015). National, regional and global causes of child mortality in 2000-2015 – reflecting on the MDG 4 and embarking on the SDG 3.2. Under preparation . 2 WHO/UNICEF. WHO/UNICEF National Immunization Coverage Estimates. Data as of 10 Jul 2015. Retrieved from http://www.who.int/immunization/monitoring_surveillance/data/en/ 3 UNICEF. Global databases 2015 based on MICS, DHS and, other national household surveys. Retrieved from http://data.unicef.org/child-health/pneumonia.html 4 UNICEF. Global databases 2015 based on MICS, DHS and, other national household surveys. Retrieved from http://data.unicef.org/child-health/diarrhoeal-disease.html 5 The DHS Program. (n.d.). Demographic and Health Surveys (DHS) Final Reports. Retrieved from http://dhsprogram.com/publications/publication-search.cfm?type=5 6 UNICEF. (2014). Multiple Indicator Cluster Surveys / MICS5. Retrieved from http://www.childinfo.org/mics5_surveys.html 7 UNICEF. Global databases, 2014, DHS, MICS, other national household surveys and UNICEF. Retrieved from http://data.unicef.org/nutrition/iycf.html.
Key Findings | GAPPD Package Coverage Compared to 2014 scores, 7 of the PCV, and rotavirus vaccines) and are 15 countries had improvements in achieving relatively high coverage their 2015 scores (Fig. 3), with the with each. By contrast, in countries largest increases seen in Angola with large populations of children (+15%), Ethiopia (+10%), and DRC (+8%). under the age of five years, such as Afghanistan and Sudan, respectively, India, Nigeria, China and Indonesia, also saw increases in their overall PCV and rotavirus vaccine have not GAPPD scores (+5 and +7, respectively) yet been introduced into the national and India and Nigeria raised their score immunization schedule, which slightly (+2%). It is quite notable that contributes to stagnation of their India has the lowest GAPPD score overall GAPPD scores. among the Asian countries evaluated in this report, despite its resources. Moving the needle in large countries Indonesia, Niger, and China had no where a large portion of the world’s improvements in their overall score. under-five population lives has Overall GAPPD scores decreased in proven difficult and slow. As evident three countries: Pakistan and Chad in Figure 4, India and Nigeria, which decreased only slightly (-1%), but bear the greatest burden of child Bangladesh’s score declined by 8%. deaths from pneumonia and diarrhea, Bangladesh’s lower GAPPD score was have overall GAPPD scores that largely attributable to its decreasing remain well below 50%, revealing rate of antibiotic treatment for children the substantial opportunities for with suspected pneumonia (from 71% to reduction of this burden of mortality. Without significant and 34%) and zinc coverage in children with This pattern is true for other countries accelerated progress in these diarrhea (from 41% to 12%). with large under-five populations as large countries, reduction Of the 15 countries profiled in this well, including China, Indonesia, and of preventable pneumonia report, the 3 countries with the highest Pakistan, who also have scores less and diarrhea deaths in young GAPPD scores (Tanzania, Sudan, than 50%. children globally will continue and Angola) are using all 5 vaccines to stall. protective against pneumonia and This progress will need to not only diarrhea (pertussis, measles, Hib, include introduction of the vaccines, but equitable rollout to ensure Figure 2: 2015 Overall GAPPD intervention scores for countries shown from top to maximum impact. In large countries, bottom in decreasing order of absolute child pneumonia and diarrhea deaths the phased approach for introduction of vaccines, often because of weaker Overall GAPPD Target Score systems can inadvertently result India 34% (86%) in lower than desired progress, Nigeria 31% Pakistan as subnational areas that tend to 46% Democratic Republic 47% introduce last are also areas where of the Congo Angola 65% disease burden is highest. A deliberate Ethiopia 48% effort to introduce interventions in Indonesia 37% highest burden areas in parallel with Chad 22% Afghanistan 49% system strengthening is needed to Niger 38% achieve the greatest impact. China 45% Sudan 70% Bangladesh 50% Somalia 20% No missing data values Tanzania, United 72% 1 missing data value Republic of 4+ missing data values 0% 10 20 30 40 50 60 70 80 90 100% Source: World Health Organization (WHO). (2015). WHO vaccine-preventable diseases: monitoring system. 2015 global summary. Last updated 8 Sep 2015. Retrieved from http://apps.who.int/immunization_monitoring/globalsummary/indicators IVAC at Johns Hopkins University 14
Key Findings | GAPPD Package Coverage When evaluating pneumonia and diarrhea interventions separately, Countries consistently scored higher on their GAPPD-Pneumonia GAPPD-Pneumonia scores scores than their GAPPD-Diarrhea scores. Tanzania was the only were consistently higher than country of the 15 highest burden countries to meet the GAPPD- GAPPD-Diarrhea scores across all 15 Pneumonia target score of 84%, while no country achieved the countries, ranging from 26-84% and target 82% GAPPD-Diarrhea score. 14-59%, respectively (Fig. 5). India, DRC, Ethiopia, Angola, and Sudan made improvements to both their GAPPD- Figure 3: Change in overall GAPPD scores between 2014 and 2015 shown from top Pneumonia and GAPPD-Diarrhea scores. to bottom in decreasing order of absolute child pneumonia and diarrhea mortality In other countries, there was mixed progress, with some countries making Overall GAPPD Intervention Scores, 2015 gains on pneumonia interventions, while India 2 losing ground on diarrhea interventions, Nigeria 2 Pakistan and vice versa. For example, Nigeria -1 Democratic Republic 8 increased its GAPPD-Pneumonia score of the Congo Angola 8 15 by two percentage points, but lost the Ethiopia equivalent in its GAPPD-Diarrhea score. Indonesia 0 10 Similarly, Afghanistan’s GAPPD- Chad -1 Afghanistan 5 Pneumonia score improved by Niger 0 six percentage points, while its China 0 GAPPD-Diarrhea score dropped by two Sudan 7 Bangladesh -8 percentage points. Niger, on the other Somalia* hand, gained five percentage points in Tanzania, United Republic of* its GAPPD-Diarrhea score and lost four -10 -5 0 5 10 15 in its GAPPD-Pneumonia score. Two countries (Bangladesh and Chad) had *Not profiled in the 2014 Pneumonia & Diarrhea Progress Report; was not among the top 15 countries with the highest number of child pneumonia and diarrhea deaths in the previous year. decreases in both their GAPPD-Pneumo- nia and -Diarrhea scores. Figure 4: Absolute number of pneumonia and diarrhea deaths in under-five children This shows that progress on the child and overall GAPPD scores in the 15 highest burden countries, relative to their pneumonia and diarrhea fronts could under-five population size differ by country and that barriers to each should be addressed on the individual country level. Some countries 90 could have strong champions or funding for pneumonia interventions, 80 Sudan Tanzania but lack them for diarrhea (or vice Overall GAPPD Scores (%), 2015 70 versa), and therefore perform better in 60 Angola certain areas than others. Even within Bangladesh 50 Ethiopia countries, improvements in pneumonia Afghanistan Pakistan India compared to diarrhea and the degree to 40 Niger DRC China which each were improved could vary Indonesia 30 Chad across states and districts, especially 20 Nigeria in large, heterogeneous countries with Somalia 10 a decentralized government and health system. To devise a more tailored 0 60 120 140 solution, it is important to recognize 20 40 80 100 these potential differences across Under-5 Child Population in Each Country, 2015 (in millions) geographic areas and between the various interventions. Note: The size of each bubble represents the absolute number of under-five child deaths from pneumonia and diarrhea in each country. Pneumonia & Diarrhea Progress Report 2015 15
Key Findings | GAPPD Package Coverage Figure 5: 2015 GAPPD-Pneumonia and GAPPD-Diarrhea intervention scores for countries shown from top to bottom in decreasing order of total child pneumonia and diarrhea deaths India 45% 31% Nigeria 21% 39% 60% Pakistan 28% Democratic Republic 61% of the Congo 33% 77% Angola 52% GAPPD-Pneumonia 55% Target Score Ethiopia 42% (84%) 47% GAPPD-Diarrhea Indonesia 32% Target Score (82%) Chad 30% 14% Afghanistan 63% 31% 44% Niger 34% 56% China 42% 74% Sudan 59% 59% Bangladesh 48% Somalia 26% 14% Tanzania, United 84% Republic of 59% 0% 10 20 30 40 50 60 70 80 90 100% GAPPD Scores (%) GAPPD-Pneumonia Intervention Score GAPPD-Diarrhea Intervention Score Although none of the 15 countries minimum score achieved if a country children who need them most. Only met the 86% target for their overall were to meet the minimum standards 5 of the 15 countries met one or GAPPD score, Tanzania did meet all the for all the diarrhea-specific GAPPD more GAPPD coverage targets, with minimum targets for the pneumonia- interventions). The sluggish pace of Tanzania hitting targets for the most (6) specific GAPPD interventions, thereby progress with diarrhea interventions indicators, followed by Sudan, who met achieving the 84% target for its GAPPD- highlights the urgent need to accelerate 4 coverage targets. In total, 10 of the 15 Pneumonia score. However, no country the rate of implementation and scale countries failed to reach even one of the was even close to reaching the 82% up of diarrhea and treatment measures 10 GAPPD coverage targets. target for its GAPPD-Diarrhea score (the so that these interventions can reach IVAC at Johns Hopkins University 16
Key Findings: Prevention through Vaccination Both accelerated vaccine introductions and scale ups are needed to promptly raise coverage levels and prevent child deaths from pneumonia and diarrhea. In countries with phased vaccine introductions, slow rollout of the vaccine to all areas of the country has contributed to persistently low coverage. 17
Key Findings | Prevention through Vaccination Vaccines have long been recognized as a cornerstone to child health and survival. However, the introduction of new vaccines in developing countries has generally lagged behind use in developed countries, even though poorer countries bear a disproportionate burden of disease. For pneumonia and diarrhea, there are several vaccines that are safe and effective in preventing these diseases, such as pertussis, measles, Hib, pneumococcal, and rotavirus vaccines. concern. As we see with recent measles which is indicative of what their Hib DTP3 Coverage outbreaks in the U.S., a country that coverage rates will likely be once they had previously eliminated measles complete the transition from DTP to According to the latest WHO/UNICEF over a decade ago,10 it is important Hib-containing pentavalent vaccine in all Estimates of National Immunization for countries to recognize that their states. Somalia and Chad, on the other Coverage (WUENIC) released in 2015, population will remain vulnerable to hand, have similarly low coverage rates DTP3 rates rose in 7 of the 15 countries, outbreaks if coverage levels are not for both DTP and Hib (42% for Somalia decreased in 3 of the countries, and were high and do not stay high. For measles and 46% for Chad), which suggests that unchanged in the remaining 5 countries particularly, declining coverage levels they still have very weak immunization between 2013 and 2014. In some pose a real and substantial threat to the systems and thus require strengthening countries, such as Chad and Somalia, sustainability of previous successes of their routine immunization programs. DTP3 coverage levels are unacceptably achieved in measles prevention. low (less than 50%), indicating serious issues with delivering routine immunizations in those countries. For Hib Vaccine Coverage Hib Vaccination Coverage Target many countries with remarkably low DTP3 coverage, including Somalia, Hib vaccine, another vital vaccine political conflict has played a major for the prevention of pneumonia, is role in disrupting basic immunization widely used across the globe in every Met or Sudan services. In these areas affected by country, except for China and Thailand. Exceeded Bangladesh conflict, enhanced efforts to strengthen Children in China have access to Hib 90% Target Tanzania immunization systems are especially vaccine in the private market, but its critical, as more and more children coverage levels in the private sector are become displaced and even harder to not well documented.7 Currently, 3 of reach for preventive services.9 the 15 countries (Sudan, Bangladesh, Pakistan and Tanzania) have met or exceeded DRC the 90% GAPPD coverage target for Close to Reaching Angola Measles Coverage Hib vaccination and several countries 90% GAPPD Target Ethiopia are relatively close to reaching the (70-89%) Afghanistan For measles vaccine, coverage rates target, including Pakistan (73%), DRC increased in 3 countries, decreased in (80%), Angola, (80%), Ethiopia (77%), 6, and were unchanged for the other and Afghanistan (75%). Still, many 6 countries.8 Ten of the 15 countries countries continue to have extremely India had measles vaccine coverage at or low coverage, such as India (20%), Extremely Indonesia above 70%, with 2 (China and Tanzania) Indonesia (21%), Somalia (42%), and Low Coverage Somalia reaching nearly universal coverage Chad (46%). For India and Indonesia, low (Less than 70%) Nigeria (99%). Nevertheless, the fact that coverage of Hib vaccine is a result of measles vaccine coverage is not where incomplete introduction of the vaccine it should be for 13 of the 15 countries, throughout all states and districts in and that only 3 countries are on an the country. India and Indonesia’s DTP3 upward trajectory, should be a cause for coverage rates are much higher though, Pneumonia & Diarrhea Progress Report 2015 18
Key Findings | Prevention through Vaccination are using the vaccine. On the global recommendation of LLR (for children PCV Coverage scale, uptake of rotavirus vaccine is 2-35 months of age) and its high price especially delayed in South Asia and (costing roughly 10% of the average Although the lag in use of PCV and Southeast Asia, falling substantially Chinese monthly salary for 2 doses), rotavirus vaccines in developing behind the pace of introductions in private market coverage of rotavirus countries compared with developed Africa. Compared to the 29 (55%) vaccine in Guangzhou was expectedly countries has been significantly less countries in Africa using rotavirus low.13 For the 5 countries profiled in this than that of Hib vaccine,7 the pace of vaccine in national immunization report that are using rotavirus vaccine, introduction of these vaccines in the programs, Asia pales in comparison, coverage ranged from 18% (in Angola) highest burden countries has been with only 11 countries (24%) routinely to 97% (in Tanzania). India, Nigeria, remarkably slow, especially in large using the vaccine.11 Furthermore, the Pakistan, Indonesia, Afghanistan, and countries that have the potential to make Asian countries that have not introduced Bangladesh are planning to introduce great impact. Fifteen years after PCV’s rotavirus vaccine are also countries rotavirus vaccine, but not until 2016 first introduction in 2000, five of the with large birth cohorts, such as India, or 2017.11 In India, the country with the highest pneumonia burden countries Indonesia, and China. highest absolute number of diarrheal (India, Indonesia, Chad, China, and deaths, the vaccine is planned for Somalia) are still not using the vaccine in Although rotavirus vaccine is introduction into 4 states, initially. DRC, their routine immunization programs.11 not included in China’s national Chad, China, and Somalia have not yet India, Chad, China, and Somalia have immunization schedule, there is a made decisions regarding rotavirus not made official decisions to introduce licensed monovalent rotavirus vaccine vaccine introduction.11 the vaccine, and Indonesia is expected (LLR) available on the private market in to introduce PCV no earlier than 2017, the country.12 However, based on a 2013 Despite an overall decline in diarrhea and only in a limited area.11 Among the study of rotavirus vaccine coverage in and pneumonia mortality over time, 8 countries that have introduced PCV, Guangzhou, one of the largest cities countries must resist becoming coverage varied widely from a low of 13% in China, only about 1 in 4 children complacent as long as preventable (in Niger) to a high of 97% (in Sudan). In between the ages of 2 and 59 months disease and mortality in children still all cases, the goal of vaccine introduction received 1 dose of LLR, and even remain, especially in hard-to-reach should be to scale up access to fewer (0.5%) received 2 or more doses. areas where disease burden is high and include all children, with policy makers Given the vague and broad schedule access to care is low. prioritizing accelerated rollouts to the highest burden populations that are most Global rotavirus vaccine introductions vulnerable and most in need. Rotavirus Vaccine Coverage Compared to PCV, rollout of rotavirus vaccine in these 15 countries has been even more limited. Nine years into rotavirus vaccine’s introduction in the global market, only 5 of the 15 highest mortality burden countries (Angola, Ethiopia, Niger, Sudan, and Tanzania) Introduced – Universal (76 countries) Introduced – Subnational (4 countries) IVAC at Johns Hopkins University 19
Key Findings | Prevention through Vaccination Striving to Achieve and began in August 2013.11 This again which translated to time savings for Maintain High, Equitable underscores the importance of health workers and increased overall Vaccine Coverage strengthening immunization programs efficiency of planning efforts.14 at the national, state, and district levels; Concurrent vaccine introductions building awareness and political will for also allowed for combined advocacy Beyond the political will needed to introduction; and assuring that systems and communications efforts, introduce these vaccines, achieving at all levels have the capacity to roll out including development of key high levels of coverage among children new vaccines at an accelerated pace, messages and materials.14 These remains a major challenge for many especially in high-burden states where lessons, gleaned from Tanzania’s of these countries. Of the 15 countries delivery might be particularly difficult. concurrent launch of PCV and evaluated in this report, only 2 (Sudan rotavirus vaccine, provide valuable and Tanzania) met the 90% GAPPD It is often the case that when countries insights into what is essential for a coverage target for PCV and only 1 have multiple new vaccine introductions successful dual launch. They also (Tanzania) met the same target for planned, they stagger the introductions bring to the forefront the benefits rotavirus vaccine coverage. While some so as not to overburden the system. of dual, as opposed to separate and countries improved vaccination coverage Even though it is wise to make sure that staggered, vaccine introductions. for all vaccines already introduced (of immunization programs and systems These lessons can also be taken up the five included in this report), such are well prepared to accommodate the by other countries contemplating as DRC, Ethiopia, Afghanistan, Sudan, new vaccines, delaying introduction the introduction of multiple vaccines and Tanzania; Chad’s vaccination rates means that children continue to be that target children within the same dropped for all the vaccines evaluated in at risk of infection and death each age group. this report. In Angola’s case, coverage day that the vaccines are not being rates declined for DTP, measles, and given. Meanwhile, other countries have Hib vaccine, but increased for PCV decided not to wait, opting for dual and rotavirus vaccine. India showed introductions. improvements in its DTP and measles vaccine coverage; however, in 2014, three This was the case for Tanzania, the years after Hib vaccine’s first rollout in country with the highest overall GAPPD Indian states, only 20% of children in intervention score and also one of the the country are receiving the vaccine.11 few countries among the 15 highest Likewise, Indonesia, opting to wait for burden countries that is using both an indigenously produced vaccine, was PCV and rotavirus vaccine. Tanzania slow to adopt Hib vaccine and only experienced success with their dual introduced the vaccine thirteen years PCV and rotavirus vaccine introduction after Gavi support became available for a number of reasons. First, they and over 10 years after a vaccine probe conducted cold chain assessments to study demonstrated the high burden of proactively identify and address any Hib disease. Additionally, Indonesia’s capacity or storage issues months in decentralized system has contributed to advance of the introduction. Second, a slow rollout of Hib vaccine, reaching because they were preparing two only 21% coverage, well below DTP3 vaccine introductions at once, they coverage rates after more than two were able to consolidate working years since its phased introduction groups and health worker trainings, Pneumonia & Diarrhea Progress Report 2015 20
Country Highlights: India 21
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children India PROGRESS: Strong political commitment to CHALLENGES: Slow rollout of pentavalent vaccine immunize all children in the next in high-burden states and low Hib Global rank in number of pneumonia five years vaccine coverage nationally & diarrhea child deaths: 1 Increased efforts to monitor data Lagged decision making on PCV and progress at the district levels introduction 2015 GAPPD score: 34 Launch of Mission Indradhanush, Low levels of access to appropriate aiming to expand immunization pneumonia and diarrhea treatments coverage in high-priority districts with large populations of unvaccinated and undervaccinated children In their addresses to the Global Call to zinc, antibiotics; human resources and the renewed commitment of India’s Action Summit in New Delhi in August vacancies; where the activists are; and leadership to improve child survival. 2015, Prime Minister Narendra Modi and more. This in-depth monitoring has While the introduction and rollout of Union Health Minister JP Nadda renewed contributed to some of the progress rotavirus and pentavalent vaccines are the government’s commitment to ending that India is making in implementing an in motion in India, further supported preventable maternal and child deaths integrated approach to fight pneumonia by the licensure of an indigenous in India and highlighted the strides and diarrhea. rotavirus vaccine, PCV is not yet used made to date. Heralding achievements in the UIP. In support of India’s push in neonatal health, including India’s In 2014, the Government of India toward full immunization and prevention successful elimination of maternal and announced the introduction of four new of diarrhea and pneumonia among neonatal tetanus, Prime Minister Modi vaccines, including rotavirus vaccines, children, a symposium (“Pneumococcal also called for accelerated immunization into the Universal Immunization Conjugate Vaccines in India: A Roadmap of all children in India, pledging to reach Programme (UIP) and as of November for Introduction”) will be hosted in full immunization in the next five years 2015, 20 states and Union Territories New Delhi in November 2015. The to ensure that no child in India dies of a have rolled out pentavalent vaccine, symposium will bring together experts vaccine-preventable disease. With one which includes DTP and Hib vaccines. and partners from across India and in every five global child deaths from the world to discuss the experience of diarrhea or pneumonia occurring in India, Working to ensure that the currently PCV introduction in other countries and the need for an equitable, comprehensive available vaccines are reached potential steps for introduction and approach to preventing and treating by the children who need them rollout of PCV in India. A country-led these diseases is critical, including most, the Ministry of Health and committee will discuss evidence-based expanding exclusive breastfeeding Family Welfare launched Mission policy options for state selection and and access to antibiotics, along with Indradhanush (“Rainbow” Mission). develop a proposed PCV rollout strategy increases in vaccine introduction Launched in December 2014, the for the Ministry’s consideration. and use. aim of Mission Indradhanush was to expand immunization coverage in 201 District Level Task Forces in India high-focus districts comprising 50% of monitor data regarding progress on a unvaccinated or partially vaccinated variety of indicators, including those on children in phase I, and add nearly 300 pneumonia and diarrhea. The District more districts to the program in phase Magistrates have shown detailed II. The efforts to strengthen political knowledge of various basic indicators of commitment and mobilize communities program strength, including stock levels to scale up efforts that target the of commodities, such as vaccines, ORS, hardest-to-reach communities signal The government of India’s continued commitment to child health is inspiring. Each great stride helps save more lives and prevent illness. It’s important to continue to demand the same level of momentum for the fight against vaccine-preventable diseases. IVAC at Johns Hopkins University 22
Country Highlights: Indonesia 23
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children Indonesia PROGRESS: The Ministry of Health has called CHALLENGES: Indonesia’s decentralized health for a phased introduction of PCV in system makes access to prevention Global rank in number of pneumonia 2017 and 2018 in Central Lombok. and treatment services for pneumonia and diarrhea difficult, & diarrhea child deaths: 7 A limited introduction of rotavirus especially for hard-to-reach vaccine is also planned within a populations. 2015 GAPPD score: 37 similar timeframe. Local preference for a Halal vaccine A new law which sets forth may complicate decision making if minimum healthcare standards an indigenous trypsin-free vaccine will help strengthen the healthcare does not become available soon. delivery system and improve accountability. To achieve universal vaccine coverage, plans for expanded rollout of PCV and rotavirus vaccine in all regions of Indonesia are needed. Indonesia has made impressive progress introduction of rotavirus vaccine is rollout, particularly on islands where in reducing childhood mortality and planned in a similar timeframe as the immunization system is not strong. reaching MDG4 goals. Despite this well, with an indigenous porcine-free Thus, raising awareness and advocating progress, the country ranks seventh rotavirus vaccine. On the treatment for vaccines must be a priority at both in absolute number of pneumonia and side, a new law in Indonesia calling national and local levels to ensure the diarrhea child deaths. The decentralized for minimum standards in healthcare needed changes are implemented. health system covering over 17,000 may facilitate the strengthening of Additionally, plans for timely and islands makes access to care a the healthcare system and improve widespread rollout of pneumococcal challenge and often leaves hard-to-reach accountability. and rotavirus vaccines introduction populations without adequate will need to be expanded to additional pneumonia and diarrhea prevention This news, while a positive signal provinces in order to achieve universal and care. The country is taking steps to for children in the country, is still access and coverage. address the burden of pneumonia and complicated by several factors. diarrhea, however. With Indonesia graduating from Beyond the logistical issues, there may Gavi support, it will be increasingly be other unique challenges that could Indonesia plans to introduce both important to advocate for dedicated hinder the introduction of vaccines pneumococcal conjugate and rotavirus funding to ensure that PCV rolls out in as planned at the national level. For vaccine in the next several years. a timely and equitable manner. Given example, demand for a Halal vaccine The Ministry of Health has called its decentralized system, buy-in from and perceptions about whether current for introduction of pneumococcal both districts and provinces will be vaccines are haram (prohibited) conjugate vaccine in 2017 in Central especially crucial; they will need to complicate decision making, should an Lombok, following a recommendation understand the value of the vaccine and indigenous porcine trypsin-free vaccine by The Komite Pensihat Ahli Imunisasi prioritize strengthening of systems to not be available within a reasonable Nasional or Indonesia Technical Advisory enable smooth and impactful vaccine time period. This challenge could be Group on Immunization (ITAGI) and the delivery. Declining DTP3 coverage reasonably managed with strengthened vaccine’s inclusion in the multi-year rates (currently at 78% for 2014), even advocacy, engagement of Muslim plan. This phased introduction will though the Indonesian government has community leaders, and contingency continue in additional provinces and if strengthened immunization activities planning efforts for other acceptable the indigenous whole-cell pneumococcal during the last five years, also strike alternatives to help ensure sustained vaccine (now in clinical trials) is licensed, a note of concern about the certainty progress against diarrhea as well as a switch will likely be made. A limited of achieving the goal of universal pneumonia is made. Indonesia has made significant investments in the immunization program over the past five years, but faces many challenges to ensure both equity and sustainability of their program as they transition out of Gavi support. Pneumonia & Diarrhea Progress Report 2015 24
Country Highlights: Nigeria 25
Executive Summary | Global Burden of Pneumonia and Diarrhea in Children Nigeria PROGRESS: CHALLENGES: Delisting from polio-endemic Funding gaps for immunization and countries by WHO other GAPDD interventions Global rank in number of pneumonia Weak central coordination across & diarrhea child deaths: 2 Successful roll out of pentavalent GAPPD strategies and interventions vaccine across the nation No central point of accountability for 2015 GAPPD score: 31 Phased introduction of PCV the rollout of comprehensive GAPPD interventions and continuing progress Plans to apply for Rotavirus in 2016 Inadequate access to effective and introduce by 2018 prevention and treatment of pneumonia and diarrheal cases Despite missing the MDG 4 target, strategy is to employ performance environmental conditions. Nigeria has Nigeria has reason for cautious management to drive accountability made good progress on immunization optimism; under-five mortality dropped and action to achieve targets on with three new vaccines (pentavalent, 49% between 1990 and 2015. But 750,000 coverage of interventions and number pneumococcal conjugate vaccine, Nigerian children still die every year of lives saved. In 2015, the World Bank and IPV) in four years, being delisted from largely preventable causes. Thus boosted the program with 500 million from WHO’s polio-endemic countries, the country is still far from fulfilling USD to “pay” state governments for and making modest increases in the “Promise Renewed” of ending results on targets. While the SOML immunization coverage. However, preventable child deaths. program is an opportunity to increase the rising vaccine program costs and access to the multi-pronged GAPPD looming transition out of Gavi support Pneumonia and diarrhea are top killers interventions that “protect, prevent, and are real challenges. of children in Nigeria. Unfortunately, treat”, national coordination along the progress on pneumonia control is slow. GAPDD strategies remains weak and The “treat” strategy also has gaps. From the year 2000 to 2013, the number implementation of the interventions There is limited access to diagnostic of under-five deaths from pneumonia variable. technologies, (X-ray machines and remains unchanged. In contrast, deaths pulse-oximeters) and to oxygen for from malaria and measles declined Under “protect”, there has been no high- treatment. Even low-tech strategies by 34% and 97% respectively. The visibility effort to promote breastfeeding such as integrated community case country’s low GAPPD intervention score since the Baby Friendly Initiative (BFI) of management and referrals have not of 31% reflects the poor coverage of key the 1990s. It is not surprising therefore been optimized. As a result, only interventions and explains the lack of that only 17% of Nigerian children are 35% of children with symptoms of progress. exclusively breastfed for the first six acute respiratory infections receive months of life, as against the GAPPD antibiotics for their illness. Nigeria has The Nigerian government has taken target of 50%.To move the breastfeeding begun local production of dispersible concrete steps to address the high child agenda forward, a partnership for amoxicillin tablets and the distribution mortality. In 2012, the then President, nutrition advocacy has begun working of ORS and zinc supplementation, while Goodluck Jonathan, launched the to raise awareness, including the Future enhancing integrated community case flagship Saving One Million Lives Assured Initiative of the Wife of the management to improve treatment Initiative (SOML). This Initiative aimed President of Nigeria, Mrs. Aisha Buhari. access. Ending preventable child deaths to rapidly increase access to proven by 2030 will require financing, advocacy, interventions across six maternal Programs to “prevent” pneumonia and and strong systems to scale up GAPPD newborn and child health program areas. diarrhea include vaccination; prevention interventions. The SOML focuses on health outcomes of vertical transmission of HIV; and rather than outputs or inputs. The core improving water, sanitation, and Nigeria’s success with polio eradication is a demonstration of her strong commitment to the health of her children. The same commitment should inspire the scale up of GAPPD interventions, to battle and defeat two of the biggest killers of Nigerian children. IVAC at Johns Hopkins University 26
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