LIMA-PERU - VIRTUAL 9-10 ZOOM STREAMING - Sociedad Peruana de Oncología Médica
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LIMA-PERU Foto: Pixabay INFORMATION Telephone: 997 930 727 JULY Mail: spom@spomedica.org ZOOM STREAMING 9-10 VIRTUAL VALIDACIÓN PARA RECERTIFICACIÓN MÉDICA
Estimados colegas: La Sociedad Peruana de Oncología La confianza depositada por ASCO Médica, como sociedad primaria (American Society of Clinical tiene por principio la educación Oncology) y el trabajo realizado por medica continua y la generación las gestiones previas, nos permiten de conocimiento. continuar con el desarrollo de la edición XII Best of ASCO, evento En este tiempo inédito hemos científico que engloba los principales aprendido que el conocimiento avances en prevención, diagnóstico, científico independiente de las tratamiento, salud pública, políticas diferentes modalidades, no se sanitarias, terapia de soporte entre detiene y es la base de nuestro otros. desarrollo como médicos y por lo tanto la posibilidad de continuar Estamos seguros que en estos laborando en beneficio de nuestros días nos enriqueceremos con la pacientes y de nuestra sociedad. participación y experiencia de ponentes y expertos nacionales e La edición 56ta. de la Reunión de internacionales, por este motivo y ASCO se ha caracterizado por a nombre de la Junta Directiva les integrar el conocimiento y sobre damos la bienvenida a este todo incentivar las relaciones prestigioso evento académico. institucionales desde la accesibilidad, desarrollo de nuevas drogas hasta los programas de pacientes Silvia Neciosup Delgado MD sobrevivientes. Spom President
BEST OF ASCO 2021 July 9 OPENNING 13:50-14:00 h SILVIA NECIOSUP DELGADO MD Presentador: Carlos Desposorio MD 14:00-14:35 h GENITOURINARY CANCER-KIDNEY AND BLADDER Final analysis of KEYNOTE-426: Pembrolizumab plus axitinib versus sunitinib as first-line therapy for advanced clear cell renal cell carcinoma (ccRCC). Health-related quality-of-life (HRQoL) analysis from the phase 3 CLEAR trial of lenvatinib (LEN) plus pembrolizumab (PEMBRO) or everolimus (EVE) versus su- nitinib (SUN) for patients (pts) with advanced renal cell carcinoma (aRCC). Avelumab first-line (1L) maintenance for advanced urothelial carcinoma (UC): Analysis of clinical and genomic subgroups from the JAVELIN Bladder 100 trial. Nivolumab plus cabozantinib in patients with non-clear cell renal cell carcinoma: Results of a phase 2 trial. Ray Manneh Kopp MD VIDEO MSD 14:35-15:10 h Presentadora: Zaida Morante MD GENITOURINARY CANCER-PROSTATE, TESTICULAR, AND PENILE A phase 3 trial with a 2x2 factorial design of abiraterone acetate plus predniso- ne and/or local radiotherapy in men with de novo metastatic castration-sensitive prostate cancer (mCSPC): First results of PEACE-1. Association of increased intensity of prostate-specific antigen screening in youn- ger African American men with improved prostate cancer outcomes. The CADMUS trial: A paired cohort, blinded study comparing multiparametric ultrasound targeted biopsies with multiparametric MRI targeted biopsies in the detection of clinically significant prostate cancer. Milagros Huaringa MD
BEST OF ASCO 2021 VIDEO TECNOFARMA Presentador: Miguel Ticona MD 15:10-15:35 h SARCOMA Treatment delays are associated with an unfavorable outcome in patients with localized Ewing sarcoma: A retrospective analysis of data from the GPOH Eu- ro-E.W.I.N.G.99 trial. Eribulin and gemcitabine in previously treated patients with advanced liposarco- ma or leiomyosarcoma: A multicenter, single-arm, phase 2-trial. High clinical activity of pembrolizumab in chordoma, alveolar soft part sarcoma (ASPS) and other rare sarcoma histotypes. Andrés Cardona MD VIDEO BAYER 15:35-16:00 h Presentador: Eduardo Nuñez MD CENTRAL NERVOUS SYSTEM TUMORS Alliance A071601: Phase II trial of BRAF/MEK inhibition in newly diagnosed papi- llary craniopharyngiomas. Efficacy and safety of larotrectinib in adult and pediatric patients with tropomyo- sin receptor kinase (TRK) fusion-positive primary central nervous system tumors Long-term results of the GEINO 140 TRIAL: randomizing patients to stop or to continue temozolomide until 12 cycles Andrés Cardona MD VIDEO ELI LILLY
JULY 9 Presentadora: Denisse Castro MD 16:00-16:35 h MELANOMA/SKIN CANCER Relatlimab (RELA) + nivolumab (NIVO) versus NIVO in first-line advanced mela- noma: Primary phase 3 results from RELATIVITY-047 (CA224-047). Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase 3 trial, pembrolizumab versus placebo after complete resection of high-risk stage III melanoma. CheckMate 067: 6.5-year outcomes in patients (pts) with advanced melanoma. Neoadjuvant and adjuvant nivolumab (nivo) with anti-LAG3 antibody relatlimab (rela) for patients (pts) with resectable clinical stage III melanoma. Teresa Puertolas MD VIDEO BRISTOL MYERS SQUIBB Presentadora: Denisse Castro MD 16:35-17:05 h Symposium BRISTOL MYERS SQUIBB LARGOS SUPERVIVIENTES CON LA INMUNOTERAPIA INCLUSO EN SITUACIONES DE MAL PRONÓSTICO Teresa Puertolas MD VIDEO PFIZER Presentadora: Mivael Olivera MD 17:05-17:40 h HEAD AND NECK CANCER Camrelizumab versus placebo combined with gemcitabine and cisplatin for re- current or metastatic nasopharyngeal carcinoma: A randomized, double-blind, phase III trial. Cabozantinib versus placebo in patients with radioiodine-refractory differentia- ted thyroid cancer who have progressed after prior VEGFR-targeted therapy: Re- sults from the phase 3 COSMIC-311 trial. Metronomic capecitabine as adjuvant therapy in locoregionally advanced naso- pharyngeal carcinoma: A phase 3, multicenter, randomized controlled trial. Ricard Mesia MD
BEST OF ASCO 2021 VIDEO NOVARTIS VIDEO EUROFARMA Presentadora: Natalia Valdivieso MD 17:40-18:15 h GYNECOLOGIC CANCER Optimal treatment duration of bevacizumab (BEV) combined with carboplatin and paclitaxel in patients (pts) with primary epithelial ovarian (EOC), fallopian tube (FTC) or peritoneal cancer (PPC): A multicenter open-label randomized 2-arm phase 3 ENGOT/GCIG trial of the AGO Study Group, GINECO, and NSGO (AGO-OVAR 17/BOOST, GINECO OV118, ENGOT Ov-15, NCT01462890). Intensive versus minimalist follow-up in patients treated for endometrial cancer: A multicentric randomized controlled trial (The TOTEM study—NCT00916708). Mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients (pts) with plati- num-agnostic ovarian cancer: Final analysis. Maintenance vigil immunotherapy in newly diagnosed advanced ovarian cancer: Efficacy assessment of homologous recombination proficient (HRP) patients in the phase IIb VITAL trial. René Muñoz MD VIDEO JANSSEN VIDEO ROCHE Presentadora: Luz Ventura MD 18:15-18:45 h Symposium ROCHE RELEVANCIA DEL MANEJO INTEGRAL DEL CÁNCER DE PULMÓN Y SU IMPLEMENTACIÓN A TRAVÉS DE LA MEDICINA DE PRECISIÓN Santiago Ponce Aix MD
JULY 9 VIDEO BIOTOSCANA Presentadora: Luz Ventura MD 18:45-19:20 h LUNG CANCER-NON-SMALL CELL METASTATIC Pooled analyses of immune-related adverse events (irAEs) and efficacy from the phase 3 trials IMpower130, IMpower132, and IMpower150. Racial disparities in biomarker testing and clinical trial enrollment in non-small cell lung cancer (NSCLC). First-line nivolumab (NIVO) plus ipilimumab (IPI) plus two cycles of chemothera- py (chemo) versus chemo alone (4 cycles) in patients with advanced non-small cell lung cancer (NSCLC): Two-year update from CheckMate 9LA. Amivantamab in combination with lazertinib for the treatment of osimertinib-re- lapsed, chemotherapy-naïve EGFR mutant (EGFRm) non-small cell lung cancer (NSCLC) and potential biomarkers for response. Carlos Carracedo MD
BEST OF ASCO 2021 July 10 Presentador: Hugo Fuentes MD 8:00-8:35 h BREAST CANCER-LOCAL/REGIONAL/ADJUVANT Outcome of patients with an ultralow risk 70-gene signature in the MINDACT trial. Breast Cancer Index (BCI) and Prediction of Benefit from Extended Aromatase Inhibitor (AI) Therapy (tx) in HR+ Breast Cancer: NRG Oncology/NSABP B-42. De-escalated neoadjuvant pertuzumab+trastuzumab with or without paclitaxel weekly in HR-/HER2+ early breast cancer: ADAPT-HR-/HER2+ biomarker and survival results. Miguel Martin MD VIDEO ROCHE Presentador: Hugo Fuentes MD 8:35-9:05 h Symposium ROCHE BLOQUEO DUAL EN CÁNCER DE MAMA HER2+: INNOVACIÓN EN LA APLICACIÓN DEL TRATAMIENTO Mauricio Burotto MD VIDEO PFIZER Presentador: Fernando Valencia MD 9:05-9:40 h BREAST CANCER-METASTATIC Trastuzumab plus endocrine therapy or chemotherapy as first-line treatment for metastatic breast cancer with hormone receptor-positive and HER2-positive: The sysucc-002 randomized clinical trial. Dalpiciclib versus placebo plus fulvestrant in HR+/HER2- advanced breast cancer that relapsed or progressed on previous endocrine therapy (DAWNA-1): A multi- center, randomized, phase 3 study. Treatment-related side effects and views about dosage assessment to sustain quality of life: Results of an advocate-led survey of patients with metastatic breast cancer (MBC). Paula Cabrera MD
JULY 10 VIDEO EUROFARMA VIDEO NOVARTIS Presentadores: Silvia Neciosup MD-Luis Schwarz MD 9:40-10:10 h Symposium NOVARTIS CÁNCER DE MAMA LUMINAL Cristian Villanueva MD VIDEO BAYER Presentador: Daniel Enriquez MD 10:10-10:45 h HEMATOLOGIC MALIGNANCIES-PLASMA CELL DYSCRASIA-LMC Daratumumab (DARA) maintenance or observation (OBS) after treatment with bortezomib, thalidomide and dexamethasone (VTd) with or without DARA and autologous stem cell transplant (ASCT) in patients (pts) with newly diagnosed multiple myeloma (NDMM): CASSIOPEIA Part 2. Upfront autologous stem cell transplantation (ASCT) versus carfilzomib-cyclo- phosphamide-dexamethasone (KCd) consolidation with K maintenance in trans- plant-eligible, newly diagnosed (NDTE) multiple myeloma (MM). OPTIC primary analysis: A dose-optimization study of 3 starting doses of ponati- nib (PON). Elisa Quiroz MD VIDEO JANSSEN
BEST OF ASCO 2021 Presentadora: Lourdes López MD 10:45-11:15 h Symposium JANSSEN ESTADO DEL ARTE ACTUAL EN EL MANEJO DEL MM: RELEVANCIA DE LA ENFERMEDAD MÍNIMA RESIDUAL Y ABORDAJE DE ENFERMEDAD DE ALTO RIESGO Angelo Maiolino MD VIDEO BIOTOSCANA Presentadora: Lourdes López MD 11:15-11:50 h HEMATOLOGIC MALIGNANCIES-LEUKEMIA, LYMPHOMA AND CLL Effect of olutasidenib (FT-2102) on complete remissions in patients with relap- sed/refractory (R/R) mIDH1 acute myeloid leukemia (AML): Results from a plan- ned interim analysis of a phase 2 clinical trial. First results of a head-to-head trial of acalabrutinib versus ibrutinib in previously treated chronic lymphocytic leukemia Myeloablative vs non-myeloablative consolidative chemotherapy for newly diag- nosed primary central nervous system lymphoma CALGB 51101 (Alliance) CALGB 50801 (Alliance): PET adapted therapy in bulky stage I/II classic Hodgkin lymphoma (cHL) Jacqueline Barrientos MD VIDEO ROCHE VIDEO TECNOFARMA
JULY 10 Presentador: Carlos Castañeda MD 11:50-12:15 h DEVELOPMENTAL THERAPEUTICS-IMMUNOTHERAPY Preliminary results of a phase II study of alrizomadlin (APG-115), a novel, sma- ll-molecule MDM2 inhibitor, in combination with pembrolizumab in patients (pts) with unresectable or metastatic melanoma or advanced solid tumors that have failed immuno-oncologic (I-O) drugs. Safety and efficacy of a novel anti-CD20/CD19 bi-specific CAR T-cell therapy (C-CAR039) in relapsed or refractory (r/r) B-cell non-Hodgkin lymphoma (B-NHL). Sergio Santillana MD VIDEO JANSSEN Presentador: Carlos Castañeda MD 12:15-12:40 h DEVELOPMENTAL THERAPEUTICS-MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY MyPathway HER2 basket study: Pertuzumab (P) + trastuzumab (H) treatment of a large, tissue-agnostic cohort of patients with HER2-positive advanced solid tu- mors. A phase Ib trial of belvarafenib in combination with cobimetinib in patients with advanced solid tumors: Interim results of dose-escalation and patients with NRAS-mutant melanoma of dose-expansion. Sergio Santillana MD VIDEO MSD Presentador: Carlos Aliaga MD 12:40-13:10 h Symposium MSD REDEFINIENDO LA SOBREVIDA DE PACIENTES CON NSCLC Carlos Barrios MD
BEST OF ASCO 2021 VIDEO BRISTOL MYERS SQUIBB Presentador: Carlos Aliaga MD 13:10-13:45 h LUNG CANCER-NON-SMALL CELL LOCAL-REGIONAL/SMALL CELL/OTHER IMpower010: Primary results of a phase III global study of atezolizumab vs. best supportive care after adjuvant chemotherapy in resected Stage IB-IIIA non-small cell lung cancer (NSCLC). Video-assisted thoracoscopic versus open lobectomy in patients with early-sta- ge lung cancer: One-year results from a randomized controlled trial (VIOLET). Phase 3 comparison of high-dose once-daily (QD) thoracic radiotherapy (TRT) with standard twice-daily (BID) TRT in limited stage small cell lung cancer (LS- CLC): CALGB 30610 (Alliance)/RTOG 0538. A randomized phase II trial of oral vinorelbine as second-line therapy for patients with malignant pleural mesothelioma. Oscar Arrieta MD VIDEO TECNOFARMA Presentador: Cristian Pacheco MD 13:45-14:15 h Symposium TECNOFARMA IMPACTO DEL USO DE ANTIEGFR´S EN PRIMERA LÍNEA DE TRATAMIENTO EN CÁNCER COLORRECTAL METASTÁSICO RASWT Alan Burguete Torres MD VIDEO ELI LILLY
JULY 10 Presentador: Cristian Pacheco MD 14:15-14:50 h GASTROINTESTINAL CANCER-COLORECTAL AND ANAL Final overall survival for the phase 3 KN177 study: Pembrolizumab versus che- motherapy in microsatellite instability-high/mismatch repair deficient metastatic colorectal cancer. Oral maintenance capecitabine versus active monitoring for patients with metas- tatic colorectal cancer (mCRC) who are stable or responding after 16 weeks of first-line treatment: Results from the randomized FOCUS4-N trial. Trastuzumab deruxtecan (T-DXd; DS-8201) in patients (pts) with HER2-expres- sing metastatic colorectal cancer (mCRC): Final results from a phase 2, multicen- ter, open-label study (DESTINY-CRC01). The TRUSTY study: A randomized phase 2/3 study of trifluridine/tipiracil plus be- vacizumab versus irinotecan and fluoropyrimidine plus bevacizumab as second-li- ne treatment in patients with metastatic colorectal cancer. Erika Ruiz MD VIDEO BRISTOL MYERS SQUIBB Presentador: Frank Ruiz MD 14:50-15:20 h Symposium BRISTOL MYERS SQUIBB EL ROL DE LA INMUNOTERAPIA EN EL MANEJO DEL CÁNCER GÁSTRICO AVANZADO Juan Manuel O’Connor MD VIDEO NOVARTIS
BEST OF ASCO 2021 | JULY 10 Presentador: Frank Ruiz MD 15:20-15:55 h GASTROINTESTINAL CANCER-GASTROESOPHAGEAL, PANCREATIC, AND HEPATOBILIARY Liposomal irinotecan (nal-IRI) in combination with fluorouracil (5-FU) and leuco- vorin (LV) for patients with metastatic biliary tract cancer (BTC) after progres- sion on gemcitabine plus cisplatin (GemCis): Multicenter comparative randomi- zed phase 2b study (NIFTY). Adjuvant nivolumab (NIVO) in resected esophageal or gastroesophageal junction cancer (EC/GEJC) following neoadjuvant chemoradiotherapy (CRT): expanded efficacy and safety analyses from CheckMate 577. Nivolumab (NIVO) plus ipilimumab (IPI) or NIVO plus chemotherapy (chemo) versus chemo as first-line (1L) treatment for advanced esophageal squamous cell carcinoma (ESCC): First results of the CheckMate 648 study. Hepatic arterial infusion chemotherapy of oxaliplatin plus fluorouracil versus so- rafenib in advanced hepatocellular carcinoma: A biomolecular exploratory, ran- domized, phase 3 trial (The FOHAIC-1 study). Paola Montenegro MD VIDEO BAYER Presentadora: Gladys Giraldo MD 15:55-16:25 h Symposium BAYER EL DESAFÍO EN HEPATOCARCINOMA. ¿CÓMO NAVEGAR HACIA UNA SECUENCIACIÓN ÓPTIMA DEL TRATAMIENTO? Leonardo Da Fonseca MD CLAUSURA 16:25-16:30 h SILVIA NECIOSUP DELGADO MD
Sociedad Peruana de Oncología Médica Dra. Silvia Patricia Neciosup Delgado Presidente Dr. Alejandro Figueroa Torrejón Vicepresidente Dr. Hugo Alejandro Fuentes Rivera Secretario general Dra. Paola Montenegro Beltrán Secretaria de acción científica Dr. Carlos Desposorio Lozano Secretario de finanzas Dr. Oscar Carnero Fuentes Secretario de filiales Dra. Essy Maradiegue Chirinos Vocal de actas Dr. Marco Gálvez Villanueva Vocal de ética, juicio y opinión
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